What are the cheapest airlines flying from Columbus to Panama City round-trip?

Currently priced at $413, Delta will fly you from Columbus to Panama City and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from United Airlines and American Airlines - these airlines can fly you to your destination from $418 and $435, respectively. Delta is 31% cheaper than the average price of flights available within the next 90 days to this destination.

What is the cheapest day to fly from Columbus to Panama City?

Travelers seeking maximum savings on their Columbus to Panama City flight should consider departing on Wednesday mornings when fares are most often at their lowest. Thursday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Panama City ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama City when rainfall is around 0.4 in.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

What are the most popular airlines that fly from Columbus to Panama City?

When booking a flight from Columbus to Panama City, you may want to consider flying on American Airlines, Delta or United Airlines as they are the most popular for this route.

What is the cheapest day to fly round-trip from Columbus to Panama City?

Flights from Columbus to Panama City are found to be more expensive on Wednesday. This shouldn't discourage you from searching as you can still find great deals by being flexible with your options. Use our search form to find deals on tickets to Panama City.

How far in advance should I book a flight from Columbus to Panama City?

Travelers have found it’s best to book a flight 13 days in advance to save up to 120% compared to booking the same week of travel. As your travel date approaches, the cost of this flight route may potentially increase. While opting to book 13 days out may not be an option for all, there are still additional ways to secure a deal in the near future. You might find a flight from Columbus to Panama City 1-2 weeks in advance for as low as $263, or $580 for flights within the next 24 hours.

What is the cheapest month to fly from Columbus to Panama City?

The best pricing can be found in the month of October. Prices to Panama City from Columbus average $600. You can even find prices in October for less than $600, as users have found deals to Panama City from as low as $436. The month of December appears to be one of the more expensive times to travel to Panama City from Columbus. Flying in the targeted month can save you up to 69%.

What airport do you fly into for flights to Panama City from Columbus?

Panama City Tocumen Intl (PTY) is the airport you will fly into if you book a flight from Columbus to Panama City. You should not have trouble finding flights to Tocumen Intl from Columbus; the airport handles an average of 0 inbound flights from Columbus per day. You should also have plenty of airline options to choose from since 3 airlines have flights to the Panama City airport from Columbus. It is only a 11.4 mi journey from Tocumen Intl (PTY) to Panama City’s city center.

Can I find deals for flights from Columbus to Panama City that include hotel bookings?

Yes. In addition to deals on Columbus to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Columbus to Panama City?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Panama City.

Can I find deals for business class flights from Columbus to Panama City?

Yes. Cheapflights offers flight deals from Columbus to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$273+ Flights from Columbus to Panama City

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Cheapflights Tip: The best prices from Columbus to Panama City Tocumen Intl are usually found in October or August, booked 12 days in advance, depart on a Wednesday or Monday and return on a Monday

Cheap flight deals from Columbus to Panama City

Round-trip from	$413 (Delta)
One-way from	$273 (United Airlines)
Popular in	December
Cheapest in	October
Average price	$514

From Columbus to Panama City Tocumen Intl

Search Deals

One-way flight from Columbus to Panama City Tocumen Intl

Search Deals

Highest demand for flights based on searches. 21% potential increase in price ($166 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 6% potential price decrease ($38 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in July 2025

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Find flight deals from Columbus to Panama City

Cheapest flights from Columbus to Panama City
Explore the most affordable flight options available from Columbus to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.

Wed 10/86:05 amCMH - PTY

1 stop7h 42mDelta

Mon 10/202:12 pmPTY - CMH

1 stop7h 04mDelta

Deal found 7/1

$413

Wed 10/86:30 amCMH - PTY

1 stop8h 44mUnited Airlines

Mon 10/203:30 pmPTY - CMH

2 stops20h 47mUnited Airlines

Deal found 7/1

$418

Wed 10/86:50 pmCMH - PTY

2 stops20h 10mAmerican Airlines

Mon 10/203:19 pmPTY - CMH

2 stops19h 09mAmerican Airlines

Deal found 7/1

$435

Thu 9/115:15 amCMH - PTY

2 stops19h 55mMultiple Airlines

Sun 9/143:20 amPTY - CMH

2 stops13h 36mMultiple Airlines

Deal found 7/1

$520

Thu 9/117:56 pmCMH - PTY

3 stops17h 39mAvianca

Mon 9/151:30 pmPTY - CMH

3 stops19h 03mAvianca

Deal found 7/1

$687

Best flights from Columbus to Panama City
Discover carefully curated flight deals from Columbus to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 2, 2025.

Wed 10/86:05 amCMH - PTY

1 stop7h 42mDelta

Mon 10/202:12 pmPTY - CMH

1 stop7h 04mDelta

Deal found 7/2

$413

Wed 10/86:30 amCMH - PTY

1 stop13h 07mUnited Airlines

Mon 10/203:30 pmPTY - CMH

2 stops17h 28mUnited Airlines

Deal found 7/2

$418

Wed 10/86:50 pmCMH - PTY

2 stops20h 10mAmerican Airlines

Mon 10/203:19 pmPTY - CMH

2 stops19h 09mAmerican Airlines

Deal found 7/1

$435

Thu 9/115:15 amCMH - PTY

2 stops19h 55mMultiple Airlines

Sun 9/143:20 amPTY - CMH

2 stops13h 36mMultiple Airlines

Deal found 7/1

$520

Thu 9/117:56 pmCMH - PTY

3 stops17h 39mAvianca

Mon 9/151:30 pmPTY - CMH

3 stops19h 03mAvianca

Deal found 7/1

$687

Last-minute flights from Columbus to Panama City
Discover last-minute flight deals from Columbus to Panama City. Data last updated July 2, 2025 and is based on user searches.

Sat 7/512:34 pmCMH - PTY

1 stop7h 28mDelta

Fri 7/182:28 pmPTY - CMH

1 stop9h 12mDelta

Deal found 7/1

$630

Tue 7/86:30 amCMH - PTY

1 stop13h 07mUnited Airlines

Thu 7/177:55 amPTY - CMH

1 stop15h 04mUnited Airlines

Deal found 7/2

$590

Tue 7/87:45 pmCMH - PTY

3 stops17h 50mAvianca

Thu 7/178:10 pmPTY - CMH

2 stops12h 43mAvianca

Deal found 7/1

$1,199

Sun 7/276:54 pmCMH - PTY

2 stops20h 21mAmerican Airlines

Fri 8/11:55 pmPTY - CMH

2 stops20h 50mAmerican Airlines

Deal found 7/1

$516

Mon 7/285:05 amCMH - PTY

2 stops20h 40mMultiple Airlines

Wed 7/303:20 amPTY - CMH

2 stops19h 58mMultiple Airlines

Deal found 7/2

$569

Sat 8/166:30 amCMH - PTY

1 stop13h 07mUnited Airlines

Sat 8/233:30 pmPTY - CMH

2 stops20h 40mUnited Airlines

Deal found 7/2

$452

One-way flights from Columbus to Panama City
Search for one-way flight options from Columbus to Panama City. Find affordable one-way fares based on user searches. Data last updated July 2, 2025.

Mon 7/711:42 amCMH - PTY

1 stop7h 55mUnited Airlines

Deal found 7/1

$273

Mon 7/76:13 amCMH - PTY

2 stops9h 02mAmerican Airlines

Deal found 7/1

$293

Mon 7/78:53 pmCMH - PTY

3 stops40h 42mMultiple Airlines

Deal found 7/1

$409

Cheapflights Fare Finder

Use the filters below to find and compare flights from Columbus to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 10/8

6:05 am-12:47 pm

1 stop7h 42m

Panama City Tocumen Intl

Mon 10/20

2:12 pm-10:16 pm

1 stop7h 04m

$413

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 10/8

6:30 am-6:37 pm

1 stop13h 07m

Panama City Tocumen Intl

Mon 10/20

3:30 pm-9:58 am

2 stops17h 28m

$418

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 10/8

6:50 pm-2:00 pm

2 stops20h 10m

Panama City Tocumen Intl

Mon 10/20

3:19 pm-11:28 am

2 stops19h 09m

$435

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Thu 9/11

5:15 am-12:10 am

2 stops19h 55m

Panama City Tocumen Intl

Sun 9/14

3:20 am-5:56 pm

2 stops13h 36m

$520

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Thu 9/11

7:56 pm-12:35 pm

3 stops17h 39m

Panama City Tocumen Intl

Mon 9/15

1:30 pm-9:33 am

3 stops19h 03m

$687

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Mon 7/7

11:42 am-6:37 pm

1 stop7h 55m

$273

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Mon 7/7

6:13 am-2:15 pm

2 stops9h 02m

$293

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Mon 7/7

8:53 pm-12:35 pm

3 stops40h 42m

$409

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Best time to book a flight from Columbus to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Columbus with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus to Panama City

How far ahead should I book a flight from Columbus to Panama City?

The price you pay for your flight from Columbus to Panama City may vary depending on when you book. For the best chance of a lower fare, look to book 12 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Columbus to Panama City?

Currently, October is the cheapest month in which you can book a flight from Columbus to Panama City (average of $478). Flying from Columbus to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CMH to PTY?

It’s typically best to fly out from Columbus to Panama City in the afternoon. Doing so could potentially save you 20% on the flight price compared to flying in the morning, which is usually more expensive.

How much does it cost to fly round-trip from Columbus to Panama City?

Reviews of airlines servicing Panama City

Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Columbus to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,975 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,975 reviews

Delta

8.0

Very good

7,975 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

United Airlines

7.4

Good

8,861 reviews

Delta

8.0

Very good

7,975 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,975 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Avianca

6.7

Okay

2,363 reviews

Delta

8.0

Very good

7,975 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What airport do you fly into for flights to Panama City from Columbus?
Panama City Tocumen Intl (PTY) is the airport you will fly into if you book a flight from Columbus to Panama City. You should not have trouble finding flights to Tocumen Intl from Columbus; the airport handles an average of 0 inbound flights from Columbus per day. You should also have plenty of airline options to choose from since 3 airlines have flights to the Panama City airport from Columbus. It is only a 11.4 mi journey from Tocumen Intl (PTY) to Panama City’s city center.
What are the cheapest airlines flying from Columbus to Panama City round-trip?
Currently priced at $413, Delta will fly you from Columbus to Panama City and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from United Airlines and American Airlines - these airlines can fly you to your destination from $418 and $435, respectively. Delta is 31% cheaper than the average price of flights available within the next 90 days to this destination.
Can I find deals for flights from Columbus to Panama City that include hotel bookings?
Yes. In addition to deals on Columbus to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Columbus to Panama City?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Panama City.
Can I find deals for business class flights from Columbus to Panama City?
Yes. Cheapflights offers flight deals from Columbus to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Columbus to Panama City?
Currently, October is the cheapest month in which you can book a flight from Columbus to Panama City (average of $478). Flying from Columbus to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 3 airlines flying from Columbus to Panama City

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$407	Average$566	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$455	Average$548	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$468	Average$608	FlexibilityNo cancel fee	On-time71%

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$273+ Cheap flights from Columbus to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/7. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Columbus to Panama City with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Columbus to Panama City Tocumen Intl are usually found in October or August, booked 12 days in advance, depart on a Wednesday or Monday and return on a Monday

Cheap flight deals from Columbus to Panama City

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Columbus to Panama City

Cheapest flights from Columbus to Panama CityExplore the most affordable flight options available from Columbus to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.

Explore the most affordable flight options available from Columbus to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Columbus to Panama City that are best for you.

Best time to book a flight from Columbus to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Columbus with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Columbus to Panama City

How far ahead should I book a flight from Columbus to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Columbus to Panama City. Price data was last updated on June 27, 2025.

What is the cheapest month to book a flight from Columbus to Panama City?

What is the cheapest time of day to fly from CMH to PTY?

Find hourly flight availability from Columbus to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 2, 2025.

How much does it cost to fly round-trip from Columbus to Panama City?

Reviews of airlines servicing Panama City

Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Columbus to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Columbus to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Panama City from Columbus?

What are the cheapest airlines flying from Columbus to Panama City round-trip?

Can I find deals for flights from Columbus to Panama City that include hotel bookings?

How can I find direct flights from Columbus to Panama City?

Can I find deals for business class flights from Columbus to Panama City?

What is the cheapest month to book a flight from Columbus to Panama City?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Columbus to Panama City

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Columbus to Panama City

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Cheapest flights from Columbus to Panama City
Explore the most affordable flight options available from Columbus to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.