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Panama City

$157+ Cheap flights from Cali (CLO) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/29. Fares are subject to change and may not be available on all flights or dates of travel.
CLO — PTY
Oct 25 — Nov 11
Sat 10/25
Sat 11/1
1 adult, Economy
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Cheapflights Tip: The best prices from Cali Alfonso B. Aragon Intl to Panama City Tocumen Intl are usually found in March or May, booked 65 days in advance, depart on a Thursday or Wednesday and return on a Monday

Cheap flight deals from Cali to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Cali (CLO) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 25, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$276
(Copa Airlines)

One-way from

$156
(Avianca)

Popular in

January

Cheapest in

March

Average price

$209

Good round-trip deal

$154 or less

Good one-way deal

$220 or less
Provider with most accurate pricing for Cali Alfonso B. Aragon Intl-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Cali Alfonso B. Aragon Intl-Panama City Tocumen Intl flights.
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From Cali Alfonso B. Aragon Intl to Panama City Tocumen Intl
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One-way flight from Cali Alfonso B. Aragon Intl to Panama City Tocumen Intl
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Highest demand for flights based on searches. 9% potential increase in price ($19 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($4 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Cali Alfonso B. Aragon Intl to Panama City Tocumen Intl.
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Price to beat on a one-way flight from Cali Alfonso B. Aragon Intl to Panama City Tocumen Intl.
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Find flight deals from Cali to Panama City

Cheapest flights from Cali to Panama City
Explore the most affordable flight options available from Cali to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 25, 2025.

This Copa Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/33:23 pmCLO - PTY
Nonstop1h 32mCopa Airlines
Wed 10/89:20 amPTY - CLO
Nonstop1h 38mCopa Airlines
Deal found 9/24$276
This Avianca deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/224:56 pmCLO - PTY
1 stop4h 14mAvianca
Sun 10/262:55 amPTY - CLO
1 stop4h 40mAvianca
Deal found 9/24$280
This Avianca deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/319:50 amCLO - PTY
1 stop4h 10mAvianca
Sun 11/22:55 amPTY - CLO
1 stop4h 15mAvianca
Deal found 9/24$281
This Priceline deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/257:24 pmCLO - PTY
1 stop4h 46mAvianca
Thu 10/239:55 amPTY - CLO
1 stop5h 06mAvianca
Deal found 9/25$282
This Copa Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/58:48 amCLO - PTY
Nonstop1h 32mCopa Airlines
Tue 12/912:29 pmPTY - CLO
Nonstop1h 42mCopa Airlines
Deal found 9/25$287
This Avianca deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/257:09 pmCLO - PTY
1 stop5h 01mAvianca
Sun 9/2811:00 amPTY - CLO
1 stop4h 00mAvianca
Deal found 9/25$288
This Avianca deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/18:40 pmCLO - PTY
1 stop4h 20mAvianca
Mon 11/32:55 amPTY - CLO
1 stop4h 15mAvianca
Deal found 9/24$289
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/24:56 pmCLO - PTY
1 stop4h 14mAvianca
Mon 10/611:00 amPTY - CLO
1 stop4h 00mAvianca
Deal found 9/24$292
This Copa Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1012:04 pmCLO - PTY
Nonstop1h 32mCopa Airlines
Fri 2/69:55 pmPTY - CLO
Nonstop1h 41mCopa Airlines
Deal found 9/25$293
This Copa Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/288:48 amCLO - PTY
Nonstop1h 32mCopa Airlines
Thu 1/159:20 amPTY - CLO
Nonstop1h 40mCopa Airlines
Deal found 9/25$294
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/14:56 pmCLO - PTY
1 stop4h 14mAvianca
Mon 10/65:25 pmPTY - CLO
1 stop3h 53mAvianca
Deal found 9/24$295

Cheapflights Fare Finder

 
Customize your flight search to find flights from Cali to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 25, 2025.
Use the filters below to find and compare flights from Cali to Panama City that are best for you.

Fly from

Cali

Fly to

Panama City

Route

Depart

Return

Price

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

Tue 10/14

12:01 pm-1:32 pm

Nonstop1h 31m

Panama City Tocumen Intl

Fri 10/17

12:43 pm-2:25 pm

Nonstop1h 42m

$276

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

Sat 11/22

3:12 pm-4:44 pm

Nonstop1h 32m

Panama City Tocumen Intl

Mon 11/24

12:29 pm-2:11 pm

Nonstop1h 42m

$276

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

Fri 11/21

12:04 pm-1:36 pm

Nonstop1h 32m

Panama City Tocumen Intl

Mon 11/24

12:29 pm-2:11 pm

Nonstop1h 42m

$276

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

Fri 10/31

5:01 am-6:34 am

Nonstop1h 33m

Panama City Tocumen Intl

Mon 11/3

12:29 pm-2:11 pm

Nonstop1h 42m

$276

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

Fri 10/10

12:01 pm-1:32 pm

Nonstop1h 31m

Panama City Tocumen Intl

Sun 10/19

9:16 am-10:54 am

Nonstop1h 38m

$276

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

Sat 10/18

8:47 am-10:20 am

Nonstop1h 33m

Panama City Tocumen Intl

Mon 10/20

12:43 pm-2:25 pm

Nonstop1h 42m

$276

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

Fri 11/14

12:04 pm-1:36 pm

Nonstop1h 32m

Panama City Tocumen Intl

Mon 11/17

9:20 am-11:01 am

Nonstop1h 41m

$276

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

Mon 11/3

8:48 am-10:20 am

Nonstop1h 32m

Panama City Tocumen Intl

Fri 11/7

12:29 pm-2:11 pm

Nonstop1h 42m

$276

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

Thu 10/23

8:47 am-10:20 am

Nonstop1h 33m

Panama City Tocumen Intl

Thu 10/30

9:20 am-11:01 am

Nonstop1h 41m

$276

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

Tue 11/11

8:48 am-10:20 am

Nonstop1h 32m

Panama City Tocumen Intl

Fri 11/14

9:20 am-11:01 am

Nonstop1h 41m

$276

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/24

Showing 1-10 of 20 results
1
2

Compare providers for flights from Cali to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Cali to Panama City in September.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
Kiwi.comPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Cali-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Cali-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Cali-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Cali-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Cali-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Cali to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Cali with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cali to Panama City

How far ahead should I book a flight from Cali to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Cali to Panama City. Price data was last updated on September 19, 2025.

Booking 65 days in advance of your planned departure date is, on average, the best time to get cheap flights from Cali to Panama City. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Cali to Panama City?

Currently, October is the cheapest month in which you can book a flight from Cali to Panama City (average of $478). Flying from Cali to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CLO to PTY?

Find hourly flight availability from Cali to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 25, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 43% on flights from Cali to Panama City by exploring options for tickets at noon.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 25, 2025.
Read through reviews of airlines operating flights from Cali to Panama City, such as Copa Airlines and Avianca. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,539 reviews

Boarding

7.8

Comfort

7.4

Food

6.8

Crew

8.1

Entertainment

6.8

Overall

7.6

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
Copa Airlines
7.6
Good
1,539 reviews
Copa Airlines
7.6
Good
1,539 reviews

Boarding

7.8

Comfort

7.4

Food

6.8

Crew

8.1

Entertainment

6.8

Overall

7.6

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
Avianca
6.7
Okay
2,442 reviews
Copa Airlines
7.6
Good
1,539 reviews

Boarding

7.8

Comfort

7.4

Food

6.8

Crew

8.1

Entertainment

6.8

Overall

7.6

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring

Related info for your journey

Find useful and relevant information for your journey from Cali to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Cali to Panama City?

    You will need to book a flight from Cali Alfonso B. Aragon Intl to Panama City Tocumen Intl if you want to fly from Cali to Panama City. At least 3 different airlines have flights from Alfonso B. Aragon Intl (CLO) to Tocumen Intl (PTY) on a regular basis. There are 8 flights to Panama City from the Cali airport per day. If you manage to book one that is nonstop, then you can expect the flight time from CLO to PTY to be around 1h 22m.

  • How popular is this Cali to Panama City flight route?

    This flight path from Cali Alfonso B. Aragon Intl to Panama City Tocumen Intl was viewed by 12 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Cali to Panama City?

    For as low as $276, Copa Airlines can have you in Panama City from Cali in 1h 31m. Airlines will cover a distance of 434 mi. Generally, flights for this route are nonstop.

  • What are the cheapest airlines flying from Cali to Panama City round-trip?

    Flying on Wingo is currently your cheapest option to Panama City, with prices starting at $85. Additional round-trip tickets that might be worth considering are offered by Avianca and Copa Airlines, with the lowest prices starting at $146 and $156, respectively. Wingo is currently priced 57% below the average price you’ll pay for this route.

  • What are the most reliable airlines from Cali to Panama City?

    Consider United Airlines (98%), Copa Airlines (97%) or Turkish Airlines (97%) when booking your flight. These represent the most reliable airlines when flying from Cali to Panama City.

  • What are the cheapest flights from Cali to Panama City?

    On average you can expect to pay $724 for a flight from Cali to Panama City. The cheapest flight overall is $180 while the most popular route, (Cali Alfonso B. Aragon Intl - Panama City Tocumen Intl) is currently priced at $192.

  • Can I find deals for flights from Cali to Panama City that include hotel bookings?

    Yes. In addition to deals on Cali to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cali to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cali to Panama City.

  • Can I find deals for business class flights from Cali to Panama City?

    Yes. Cheapflights offers flight deals from Cali to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cali to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Cali to Panama City (average of $478). Flying from Cali to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Cali to Panama City

Discover the top 3 airlines that operate flights from Cali to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 25, 2025.
AirlineCheapestAverageFlexibilityOn-time
WingoCheapest$85Average$167FlexibilityNo cancel feeOn-time83%
AviancaCheapest$146Average$237FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$156Average$286FlexibilityNo cancel feeOn-time70%

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