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Panama City

$145+ Cheap flights from Cali (CLO) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/29. Fares are subject to change and may not be available on all flights or dates of travel.
CLO — PTY
ago. 19 — ago. 261
mar. 8/19
mar. 8/26
1 adult, Economy
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Cheapflights Tip: The best prices from Cali Alfonso B. Aragon Intl to Panama City Tocumen Intl are usually found in March or May, booked 65 days in advance, depart on a Thursday or Saturday and return on a Monday

Cheap flight deals from Cali to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Cali (CLO) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated agosto 14, 2025.

Round-trip from

$231
(Copa Airlines)

One-way from

$145
(Avianca)

Popular in

January

Cheapest in

March

Average price

$194

Good round-trip deal

$189 or less

Good one-way deal

$240 or less
From Cali Alfonso B. Aragon Intl to Panama City Tocumen Intl
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One-way flight from Cali Alfonso B. Aragon Intl to Panama City Tocumen Intl
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Highest demand for flights based on searches. 10% potential increase in price ($24 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($4 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Price to beat on a round-trip flight from Cali Alfonso B. Aragon Intl to Panama City Tocumen Intl.
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Price to beat on a one-way flight from Cali Alfonso B. Aragon Intl to Panama City Tocumen Intl.
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Find flight deals from Cali to Panama City

Cheapest flights from Cali to Panama City
Explore the most affordable flight options available from Cali to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on agosto 14, 2025.

This Copa Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/158:47 amCLO - PTY
Nonstop1h 33mCopa Airlines
mié. 11/2612:29 pmPTY - CLO
Nonstop1h 42mCopa Airlines
Deal found 8/14$231
This Copa Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/18:48 amCLO - PTY
Nonstop1h 32mCopa Airlines
vie. 12/59:20 amPTY - CLO
Nonstop1h 41mCopa Airlines
Deal found 8/14$242
This Copa Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/63:23 pmCLO - PTY
Nonstop1h 31mCopa Airlines
sáb. 9/2012:43 pmPTY - CLO
Nonstop1h 38mCopa Airlines
Deal found 8/13$244
This Copa Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/3112:04 pmCLO - PTY
Nonstop1h 32mCopa Airlines
lun. 11/39:20 amPTY - CLO
Nonstop1h 41mCopa Airlines
Deal found 8/14$256
This Avianca deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/2011:23 amCLO - PTY
1 stop5h 07mAvianca
mar. 8/263:20 amPTY - CLO
1 stop4h 58mAvianca
Deal found 8/12$257
This Avianca deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/227:24 pmCLO - PTY
1 stop5h 21mAvianca
vie. 11/145:55 pmPTY - CLO
1 stop4h 40mAvianca
Deal found 8/13$258
This Avianca deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/116:50 pmCLO - PTY
1 stop5h 20mAvianca
dom. 9/1411:00 amPTY - CLO
1 stop4h 00mAvianca
Deal found 8/14$259
This Avianca deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/266:50 pmCLO - PTY
1 stop5h 20mAvianca
lun. 9/15:25 pmPTY - CLO
1 stop5h 53mAvianca
Deal found 8/14$260
This Avianca deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/37:57 pmCLO - PTY
1 stop4h 48mAvianca
sáb. 9/69:55 amPTY - CLO
1 stop4h 25mAvianca
Deal found 8/13$261
This Avianca deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/207:57 pmCLO - PTY
1 stop4h 48mAvianca
vie. 10/315:55 pmPTY - CLO
1 stop4h 40mAvianca
Deal found 8/14$272
This Avianca deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/3111:50 amCLO - PTY
1 stop5h 05mAvianca
lun. 11/35:55 pmPTY - CLO
1 stop4h 40mAvianca
Deal found 8/14$273

Cheapflights Fare Finder

 
Customize your flight search to find flights from Cali to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 14, 2025.
Use the filters below to find and compare flights from Cali to Panama City that are best for you.

Fly from

Cali

Fly to

Panama City

Route

Depart

Return

Price

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

jue. 9/18

3:23 pm-4:54 pm

Nonstop1h 31m

Panama City Tocumen Intl

dom. 9/21

12:43 pm-2:21 pm

Nonstop1h 38m

$231

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

vie. 9/26

3:23 pm-4:54 pm

Nonstop1h 31m

Panama City Tocumen Intl

lun. 9/29

12:43 pm-2:21 pm

Nonstop1h 38m

$231

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

lun. 11/3

12:04 pm-1:36 pm

Nonstop1h 32m

Panama City Tocumen Intl

mié. 11/5

9:20 am-11:01 am

Nonstop1h 41m

$231

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

mié. 9/3

12:01 pm-1:32 pm

Nonstop1h 31m

Panama City Tocumen Intl

dom. 9/7

9:21 am-10:58 am

Nonstop1h 37m

$231

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

sáb. 10/11

8:47 am-10:20 am

Nonstop1h 33m

Panama City Tocumen Intl

mié. 10/15

12:43 pm-2:25 pm

Nonstop1h 42m

$231

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

mar. 9/16

12:01 pm-1:32 pm

Nonstop1h 31m

Panama City Tocumen Intl

sáb. 9/20

9:21 am-10:58 am

Nonstop1h 37m

$231

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

vie. 10/17

12:01 pm-1:32 pm

Nonstop1h 31m

Panama City Tocumen Intl

lun. 10/20

12:43 pm-2:25 pm

Nonstop1h 42m

$231

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

mié. 10/8

3:23 pm-4:55 pm

Nonstop1h 32m

Panama City Tocumen Intl

vie. 10/24

12:43 pm-2:25 pm

Nonstop1h 42m

$231

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

sáb. 9/20

12:01 pm-1:32 pm

Nonstop1h 31m

Panama City Tocumen Intl

mié. 9/24

12:43 pm-2:21 pm

Nonstop1h 38m

$231

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

jue. 9/11

3:23 pm-4:54 pm

Nonstop1h 31m

Panama City Tocumen Intl

sáb. 9/13

12:43 pm-2:21 pm

Nonstop1h 38m

$231

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/13

Showing 1-10 of 18 results
1
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Best time to book a flight from Cali to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Cali with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cali to Panama City

How far ahead should I book a flight from Cali to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Cali to Panama City. Price data was last updated on August 8, 2025.

Booking 65 days in advance of your planned departure date is, on average, the best time to get cheap flights from Cali to Panama City. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Cali to Panama City?

Currently, October is the cheapest month in which you can book a flight from Cali to Panama City (average of $478). Flying from Cali to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CLO to PTY?

Find hourly flight availability from Cali to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated agosto 14, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 43% on flights from Cali to Panama City by exploring options for tickets at noon.

Weekly flight availability from Cali to Panama City

Explore weekly flight availability from Cali to Panama City. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated agosto 14, 2025.

The most flights from CLO to PTY are scheduled on a Wednesday (9 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (7 on average).

How much does it cost to fly round-trip from Cali to Panama City?

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated agosto 14, 2025.
Read through reviews of airlines operating flights from Cali to Panama City, such as Copa Airlines and Avianca. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,507 reviews

Boarding

7.8

Entertainment

6.8

Comfort

7.4

Overall

7.5

Crew

8.1

Food

6.8

Reviews

1 / 20
2.0
Mediocre

Anonymous,May 2025

LIM - PTY

This was my first tome flying with this airline and needless to say, I was not impressed! The seats were not comfortable at all. You could feel the metal digging into your skin. Also, there was a kid behind me that kept putting his knees up on the seat and usually this doesn’t bother me, but I was able to feel his knees dig into my back every single time. The food was mediocore at best. There were no phone chargers on an almost 5 hour flight! Horrible experience. Will never fly with Copa airlines again!
Copa Airlines
7.5
Good
1,507 reviews
Copa Airlines
7.5
Good
1,507 reviews

Boarding

7.8

Entertainment

6.8

Comfort

7.4

Overall

7.5

Crew

8.1

Food

6.8

Reviews

1 / 20
2.0
Mediocre

Anonymous,May 2025

LIM - PTY

This was my first tome flying with this airline and needless to say, I was not impressed! The seats were not comfortable at all. You could feel the metal digging into your skin. Also, there was a kid behind me that kept putting his knees up on the seat and usually this doesn’t bother me, but I was able to feel his knees dig into my back every single time. The food was mediocore at best. There were no phone chargers on an almost 5 hour flight! Horrible experience. Will never fly with Copa airlines again!
Avianca
6.7
Okay
2,399 reviews
Copa Airlines
7.5
Good
1,507 reviews

Boarding

7.8

Entertainment

6.8

Comfort

7.4

Overall

7.5

Crew

8.1

Food

6.8

Reviews

1 / 20
2.0
Mediocre

Anonymous,May 2025

LIM - PTY

This was my first tome flying with this airline and needless to say, I was not impressed! The seats were not comfortable at all. You could feel the metal digging into your skin. Also, there was a kid behind me that kept putting his knees up on the seat and usually this doesn’t bother me, but I was able to feel his knees dig into my back every single time. The food was mediocore at best. There were no phone chargers on an almost 5 hour flight! Horrible experience. Will never fly with Copa airlines again!

Related info for your journey

Find useful and relevant information for your journey from Cali to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Cali to Panama City?

    You will need to book a flight from Cali Alfonso B. Aragon Intl to Panama City Tocumen Intl if you want to fly from Cali to Panama City. At least 3 different airlines have flights from Alfonso B. Aragon Intl (CLO) to Tocumen Intl (PTY) on a regular basis. There are 7 flights to Panama City from the Cali airport per day. If you manage to book one that is nonstop, then you can expect the flight time from CLO to PTY to be around 1h 22m.

  • How popular is this Cali to Panama City flight route?

    This flight path from Cali Alfonso B. Aragon Intl to Panama City Tocumen Intl was viewed by 14 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines flying from Cali to Panama City round-trip?

    Flying on Wingo is currently your cheapest option to Panama City, with prices starting at $97. Additional round-trip tickets that might be worth considering are offered by Avianca and Copa Airlines, with the lowest prices starting at $146 and $159, respectively. Wingo is currently priced 50% below the average price you’ll pay for this route.

  • What are the most reliable airlines from Cali to Panama City?

    Consider United Airlines (100%), KLM (97%) or Turkish Airlines (97%) when booking your flight. These represent the most reliable airlines when flying from Cali to Panama City.

  • What are the cheapest flights from Cali to Panama City?

    On average you can expect to pay $356 for a flight from Cali to Panama City. The cheapest flight overall is $167 while the most popular route, (Cali Alfonso B. Aragon Intl - Panama City Tocumen Intl) is currently priced at $161.

  • Can I find deals for flights from Cali to Panama City that include hotel bookings?

    Yes. In addition to deals on Cali to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cali to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cali to Panama City.

  • Can I find deals for business class flights from Cali to Panama City?

    Yes. Cheapflights offers flight deals from Cali to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cali to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Cali to Panama City (average of $478). Flying from Cali to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Cali to Panama City

Discover the top 3 airlines that operate flights from Cali to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
WingoCheapest$97Average$167FlexibilityNo cancel feeOn-time83%
AviancaCheapest$146Average$237FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$159Average$286FlexibilityNo cancel feeOn-time70%

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