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Panama City

$134+ Cheap flights from Cali (CLO) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/20. Fares are subject to change and may not be available on all flights or dates of travel.
CLO — PTY
Dec 12 — Dec 191
Fri 12/12
Fri 12/19
1 adult, Economy
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Cheapflights Tip: The best prices from Cali Alfonso B. Aragon Intl to Panama City Tocumen Intl are usually found in March or May, booked 65 days in advance, depart on a Thursday or Wednesday and return on a Monday

Find flight deals from Cali to Panama City

Cheapest flights from Cali to Panama City
Explore the most affordable flight options available from Cali to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 12, 2025.

This Copa Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/178:48 amCLO - PTY
Nonstop1h 32mCopa Airlines
Mon 11/249:20 amPTY - CLO
Nonstop1h 41mCopa Airlines
Deal found 11/9$232
This Copa Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/113:12 pmCLO - PTY
Nonstop1h 32mCopa Airlines
Fri 11/149:20 amPTY - CLO
Nonstop1h 41mCopa Airlines
Deal found 11/10$233
This Avianca deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/248:40 amCLO - PTY
1 stop5h 20mAvianca
Tue 1/62:55 amPTY - CLO
1 stop4h 40mAvianca
Deal found 11/10$235
This Avianca deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1411:50 amCLO - PTY
1 stop5h 05mAvianca
Fri 11/212:55 amPTY - CLO
1 stop4h 15mAvianca
Deal found 11/10$237
This Avianca deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2611:50 amCLO - PTY
1 stop5h 05mAvianca
Tue 12/22:55 amPTY - CLO
1 stop4h 40mAvianca
Deal found 11/10$238
This Priceline deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1411:50 amCLO - PTY
1 stop5h 05mAvianca
Sun 11/162:55 amPTY - CLO
1 stop4h 40mAvianca
Deal found 11/10$239
This Copa Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/248:48 amCLO - PTY
Nonstop1h 32mCopa Airlines
Fri 1/29:20 amPTY - CLO
Nonstop1h 40mCopa Airlines
Deal found 11/12$248
This Copa Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1012:04 pmCLO - PTY
Nonstop1h 32mCopa Airlines
Wed 12/173:47 pmPTY - CLO
Nonstop1h 42mCopa Airlines
Deal found 11/10$254
This Copa Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/258:48 amCLO - PTY
Nonstop1h 32mCopa Airlines
Thu 1/19:20 amPTY - CLO
Nonstop1h 40mCopa Airlines
Deal found 11/10$276
This Copa Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2212:04 pmCLO - PTY
Nonstop1h 32mCopa Airlines
Fri 1/29:20 amPTY - CLO
Nonstop1h 40mCopa Airlines
Deal found 11/12$277
This Copa Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1512:04 pmCLO - PTY
Nonstop1h 32mCopa Airlines
Tue 11/189:20 amPTY - CLO
Nonstop1h 41mCopa Airlines
Deal found 11/10$278

Cheap flight deals from Cali to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Cali (CLO) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 12, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
1 star

Round-trip from

$232
(Copa Airlines)

One-way from

$134
(Copa Airlines)

Popular in

January

Cheapest in

March

Average price

$207

Good round-trip deal

$149 or less

Good one-way deal

$239 or less
Provider with most accurate pricing for Cali Alfonso B. Aragon Intl-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Cali Alfonso B. Aragon Intl-Panama City Tocumen Intl flights.
Search Deals
From Cali Alfonso B. Aragon Intl to Panama City Tocumen Intl
Search Deals
One-way flight from Cali Alfonso B. Aragon Intl to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($16 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($4 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals
Price to beat on a round-trip flight from Cali Alfonso B. Aragon Intl to Panama City Tocumen Intl.
Search Deals
Price to beat on a one-way flight from Cali Alfonso B. Aragon Intl to Panama City Tocumen Intl.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Cali to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 12, 2025.
Use the filters below to find and compare flights from Cali to Panama City that are best for you.

Fly from

Cali

Fly to

Panama City

Route

Depart

Return

Price

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

Mon 2/2

8:48 am-10:20 am

Nonstop1h 32m

Panama City Tocumen Intl

Fri 2/13

12:29 pm-2:10 pm

Nonstop1h 41m

$232

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

Thu 1/15

8:48 am-10:20 am

Nonstop1h 32m

Panama City Tocumen Intl

Wed 1/21

9:20 am-11:00 am

Nonstop1h 40m

$232

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

Tue 3/3

3:11 pm-4:44 pm

Nonstop1h 33m

Panama City Tocumen Intl

Tue 3/10

4:00 pm-5:49 pm

Nonstop1h 49m

$233

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

Sun 2/22

5:03 am-6:34 am

Nonstop1h 31m

Panama City Tocumen Intl

Wed 2/25

12:29 pm-2:10 pm

Nonstop1h 41m

$233

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

Sun 2/8

5:03 am-6:34 am

Nonstop1h 31m

Panama City Tocumen Intl

Wed 2/11

4:00 pm-5:50 pm

Nonstop1h 50m

$233

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

Thu 2/26

12:03 pm-1:35 pm

Nonstop1h 32m

Panama City Tocumen Intl

Mon 3/2

12:29 pm-2:09 pm

Nonstop1h 40m

$233

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

Sun 2/1

12:03 pm-1:35 pm

Nonstop1h 32m

Panama City Tocumen Intl

Wed 2/4

9:25 am-11:05 am

Nonstop1h 40m

$233

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

Fri 2/27

3:11 pm-4:44 pm

Nonstop1h 33m

Panama City Tocumen Intl

Tue 3/3

12:29 pm-2:09 pm

Nonstop1h 40m

$233

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

Fri 2/6

5:03 am-6:34 am

Nonstop1h 31m

Panama City Tocumen Intl

Wed 2/11

9:25 am-11:05 am

Nonstop1h 40m

$233

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

Mon 3/16

5:03 am-6:34 am

Nonstop1h 31m

Panama City Tocumen Intl

Fri 3/20

9:25 am-11:04 am

Nonstop1h 39m

$233

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/10

Showing 1-10 of 21 results
1
2
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  • Most accurate provider: When it comes to deals on Cali-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Cali-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Cali-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Cali-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Cali-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Cali to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Cali with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cali to Panama City

How far ahead should I book a flight from Cali to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Cali to Panama City. Price data was last updated on November 7, 2025.

Booking 65 days in advance of your planned departure date is, on average, the best time to get cheap flights from Cali to Panama City. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Cali to Panama City?

Currently, March is the cheapest month in which you can book a flight from Cali to Panama City (average of $82). Flying from Cali to Panama City in July is currently the most expensive (average of $110). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CLO to PTY?

Find hourly flight availability from Cali to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 12, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 42% on flights from Cali to Panama City by exploring options for tickets at noon.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated November 12, 2025.
Read through reviews of airlines operating flights from Cali to Panama City, such as Copa Airlines and Avianca. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,563 reviews

Comfort

7.4

Food

6.9

Overall

7.6

Entertainment

6.8

Boarding

7.8

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
Copa Airlines
7.6
Good
1,563 reviews
Copa Airlines
7.6
Good
1,563 reviews

Comfort

7.4

Food

6.9

Overall

7.6

Entertainment

6.8

Boarding

7.8

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
Avianca
6.6
Okay
2,473 reviews
Copa Airlines
7.6
Good
1,563 reviews

Comfort

7.4

Food

6.9

Overall

7.6

Entertainment

6.8

Boarding

7.8

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring

Related info for your journey

Find useful and relevant information for your journey from Cali to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Cali to Panama City?

    You will need to book a flight from Cali Alfonso B. Aragon Intl to Panama City Tocumen Intl if you want to fly from Cali to Panama City. At least 3 different airlines have flights from Alfonso B. Aragon Intl (CLO) to Tocumen Intl (PTY) on a regular basis. There are 10 flights to Panama City from the Cali airport per day. If you manage to book one that is nonstop, then you can expect the flight time from CLO to PTY to be around 1h 22m.

  • How popular is this Cali to Panama City flight route?

    This flight path from Cali Alfonso B. Aragon Intl to Panama City Tocumen Intl was viewed by 19 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Cali to Panama City?

    For as low as $232, Copa Airlines can have you in Panama City from Cali in 1h 32m. Airlines will cover a distance of 434 mi. Generally, flights for this route are nonstop.

  • What are the cheapest airlines flying from Cali to Panama City round-trip?

    Flying on Wingo is currently your cheapest option to Panama City, with prices starting at $63. Additional round-trip tickets that might be worth considering are offered by Avianca and Copa Airlines, with the lowest prices starting at $146 and $161, respectively. Wingo is currently priced 69% below the average price you’ll pay for this route.

  • What are the most reliable airlines from Cali to Panama City?

    Consider Copa Airlines (95%), Turkish Airlines (95%) or KLM (94%) when booking your flight. These represent the most reliable airlines when flying from Cali to Panama City.

  • What are the cheapest flights from Cali to Panama City?

    On average you can expect to pay $665 for a flight from Cali to Panama City. The cheapest flight overall is $176 while the most popular route, (Cali Alfonso B. Aragon Intl - Panama City Tocumen Intl) is currently priced at $202.

  • Can I find deals for flights from Cali to Panama City that include hotel bookings?

    Yes. In addition to deals on Cali to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cali to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cali to Panama City.

  • Can I find deals for business class flights from Cali to Panama City?

    Yes. Cheapflights offers flight deals from Cali to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cali to Panama City?

    Currently, March is the cheapest month in which you can book a flight from Cali to Panama City (average of $82). Flying from Cali to Panama City in July is currently the most expensive (average of $110). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Cali to Panama City

Discover the top 3 airlines that operate flights from Cali to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
WingoCheapest$63Average$176FlexibilityNo cancel feeOn-time83%
AviancaCheapest$146Average$237FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$161Average$286FlexibilityNo cancel feeOn-time70%

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