$303+ Cheap flights from Buffalo (BUF) to Panama City (PTY)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/28. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — PTY
Oct 14 — Oct 211
Round-trip
1 adult, Economy
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Find cheap flights from Buffalo to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Buffalo to Panama City
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Cheapest flights from Buffalo to Panama CityExplore the most affordable flight options available from Buffalo to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2026.
Explore the most affordable flight options available from Buffalo to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2026.
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:00 am -
1 stop14h 02m
Wed 11/1810:00 am -
1 stop12h 59m
Deal found 9/12![United Airlines logo]()
$607
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2610:51 am -
1 stop9h 11m
Mon 11/210:00 am -
1 stop12h 59m
Deal found 9/11![United Airlines logo]()
$672
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:00 am -
1 stop13h 02m
Tue 12/810:00 am -
1 stop8h 10m
Deal found 9/12![United Airlines logo]()
$673
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:30 am -
1 stop14h 01m
Wed 11/410:00 am -
1 stop12h 59m
Deal found 9/11![United Airlines logo]()
$679
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/286:00 am -
1 stop14h 02m
Sat 12/510:00 am -
1 stop10h 34m
Deal found 9/14![United Airlines logo]()
$705
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:30 am -
1 stop14h 01m
Sat 10/313:41 pm -
2 stops25h 21m
Deal found 9/9![United Airlines logo]()
$724
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/284:41 pm -
2 stops21h 53m
Sat 12/53:13 pm -
1 stop8h 16m
Deal found 9/14![American Airlines logo]()
$730
Best flights from Buffalo to Panama CityDiscover carefully curated flight deals from Buffalo to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 14, 2026.
Discover carefully curated flight deals from Buffalo to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 14, 2026.
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/208:42 pm -
2 stops22h 56m
Wed 2/38:55 am -
2 stops24h 25m
Deal found 9/9![United Airlines logo]()
$611
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/205:05 am -
1 stop10h 50m
Wed 2/32:36 pm -
1 stop8h 36m
Deal found 9/9![American Airlines logo]()
$612
This Expedia deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/811:38 am -
2 stops23h 52m
Wed 11/411:30 am -
3 stops20h 38m
Deal found 9/11![Multiple Airlines logo]()
$825
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:00 am -
1 stop7h 59m
Sat 10/312:24 pm -
1 stop8h 35m
Deal found 9/9![Delta logo]()
$830
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:00 am -
1 stop13h 02m
Tue 12/810:00 am -
1 stop8h 10m
Deal found 9/12![United Airlines logo]()
$673
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/134:04 pm -
2 stops20h 36m
Sun 3/213:13 pm -
2 stops18h 45m
Deal found 9/10![American Airlines logo]()
$794
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/2311:40 am -
1 stop8h 22m
Sat 1/3010:00 am -
1 stop11h 17m
Deal found 9/13![United Airlines logo]()
$726
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/316:30 am -
2 stops22h 40m
Thu 1/74:41 pm -
2 stops16h 39m
Deal found 9/13![United Airlines logo]()
$731
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1811:40 am -
1 stop8h 22m
Sun 2/2110:00 am -
1 stop12h 37m
Deal found 9/12![United Airlines logo]()
$866
Last-minute flights from Buffalo to Panama CityDiscover last-minute flight deals from Buffalo to Panama City. Data last updated September 14, 2026 and is based on user searches.
Discover last-minute flight deals from Buffalo to Panama City. Data last updated September 14, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:30 am -
1 stop14h 01m
Wed 11/410:00 am -
1 stop12h 59m
Deal found 9/11![United Airlines logo]()
$679
This Expedia deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/811:38 am -
2 stops23h 52m
Wed 11/411:30 am -
3 stops20h 38m
Deal found 9/11![Multiple Airlines logo]()
$825
This Expedia deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:53 pm -
2 stops31h 02m
Sat 10/173:50 pm -
2 stops22h 51m
Deal found 9/12![Multiple Airlines logo]()
$785
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:30 am -
1 stop14h 01m
Sat 10/313:41 pm -
2 stops25h 21m
Deal found 9/9![United Airlines logo]()
$724
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:00 am -
1 stop7h 59m
Sat 10/312:24 pm -
1 stop8h 35m
Deal found 9/9![Delta logo]()
$830
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2610:51 am -
1 stop9h 11m
Mon 11/210:00 am -
1 stop12h 59m
Deal found 9/11![United Airlines logo]()
$672
This oojo deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/267:52 pm -
3 stops20h 08m
Mon 11/25:30 am -
2 stops13h 35m
Deal found 9/11![Avianca logo]()
$881
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:00 am -
1 stop14h 02m
Fri 10/309:30 am -
1 stop12h 29m
Deal found 9/9![United Airlines logo]()
$895
One-way flights from Buffalo to Panama CitySearch for one-way flight options from Buffalo to Panama City. Find affordable one-way fares based on user searches. Data last updated September 14, 2026.
Search for one-way flight options from Buffalo to Panama City. Find affordable one-way fares based on user searches. Data last updated September 14, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/282:00 pm -
1 stop31h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Multiple Airlines logo]()
$303
This Travelocity deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/63:33 pm -
2 stops19h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Multiple Airlines logo]()
$361
This Avianca deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/297:59 pm -
2 stops15h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Avianca logo]()
$441
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2912:54 pm -
3 stops37h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Multiple Airlines logo]()
$443
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:00 am -
1 stop14h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![United Airlines logo]()
$458
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2910:30 am -
1 stop10h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![United Airlines logo]()
$465
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:42 pm -
2 stops23h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![United Airlines logo]()
$470
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:05 am -
1 stop7h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Delta logo]()
$475
Find flight deals from Buffalo to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 14, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $607 (United Airlines) |
One-way from | $303 (Kiwi.com) |
Popular in | August |
Cheapest in | June |
Average price | $707 |
Cheapflights Fare Finder
Customize your flight search to find flights from Buffalo to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 14, 2026.
Use the filters below to find and compare flights from Buffalo to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
BuffaloPanama City
BUF Buffalo - PTY Panama City Tocumen Intl
BUFPTY
Buffalo
Wed 10/28
12:08 pm-2:10 am
2 stops15h 02m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$360
BuffaloPanama City
BUF Buffalo - PTY Panama City Tocumen Intl
BUFPTY
Buffalo
Tue 9/29
7:59 pm-10:30 am
2 stops15h 31m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$441
Quickest round-trip
BuffaloPanama City
BUF Buffalo - PTY Panama City Tocumen Intl
BUFPTY
Buffalo
Tue 9/29
10:30 am-7:31 pm
1 stop10h 01m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$465
BuffaloPanama City
BUF Buffalo - PTY Panama City Tocumen Intl
BUFPTY
Buffalo
Tue 10/6
10:30 am-7:31 pm
1 stop10h 01m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$465
BuffaloPanama City
BUF Buffalo - PTY Panama City Tocumen Intl
BUFPTY
Buffalo
Wed 1/20
8:42 pm-7:38 pm
2 stops22h 56m
Panama City Tocumen Intl
Wed 2/3
8:55 am-9:20 am
2 stops24h 25m
$611
BuffaloPanama City
BUF Buffalo - PTY Panama City Tocumen Intl
BUFPTY
Buffalo
Wed 1/20
5:05 am-3:55 pm
1 stop10h 50m
Panama City Tocumen Intl
Wed 2/3
2:36 pm-11:12 pm
1 stop8h 36m
$612
BuffaloPanama City
BUF Buffalo - PTY Panama City Tocumen Intl
BUFPTY
Buffalo
Tue 12/1
7:00 am-8:02 pm
1 stop13h 02m
Panama City Tocumen Intl
Tue 12/8
10:00 am-6:10 pm
1 stop8h 10m
$673
BuffaloPanama City
BUF Buffalo - PTY Panama City Tocumen Intl
BUFPTY
Buffalo
Sat 1/23
11:40 am-8:02 pm
1 stop8h 22m
Panama City Tocumen Intl
Sat 1/30
10:00 am-9:17 pm
1 stop11h 17m
$726
BuffaloPanama City
BUF Buffalo - PTY Panama City Tocumen Intl
BUFPTY
Buffalo
Thu 12/31
6:30 am-5:10 am
2 stops22h 40m
Panama City Tocumen Intl
Thu 1/7
4:41 pm-9:20 am
2 stops16h 39m
$731
BuffaloPanama City
BUF Buffalo - PTY Panama City Tocumen Intl
BUFPTY
Buffalo
Sat 3/13
4:04 pm-12:40 pm
2 stops20h 36m
Panama City Tocumen Intl
Sun 3/21
3:13 pm-10:58 am
2 stops18h 45m
$794
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from Buffalo to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to Panama City in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Buffalo-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Buffalo-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Buffalo-Panama City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Buffalo-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Buffalo to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Buffalo with our price prediction graph.
BUF-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 14, 2026.
Read through reviews of airlines operating flights from Buffalo to Panama City, such as Delta. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Crew
8.5
Comfort
7.8
Boarding
8.1
Overall
7.8
Entertainment
7.8
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Food
7.2
Crew
8.5
Comfort
7.8
Boarding
8.1
Overall
7.8
Entertainment
7.8
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Related info for your journey
Find useful and relevant information for your journey from Buffalo to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Buffalo and Panama City flights
Browse other Buffalo and Panama City flight options. Last updated on September 14, 2026.
Other flights from Buffalo
Browse through other flights departing from Buffalo. Flights are based on user searches made on Cheapflights and were last updated on September 14, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 14, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Buffalo to Panama City
Discover the top airline that operate flights from Buffalo to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$606 | Average$753 | FlexibilityNo cancel fee | On-timeN/A |