$311+ Cheap flights from Buffalo (BUF) to Panama City (PTY)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/25. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — PTY
Dec 9 — Dec 161
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Buffalo to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Buffalo to Panama City
Cheapest
Best
Last-minute
One-way
Cheapest flights from Buffalo to Panama CityExplore the most affordable flight options available from Buffalo to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 9, 2026.
Explore the most affordable flight options available from Buffalo to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 9, 2026.
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:00 am -
1 stop14h 02m
Mon 12/1410:00 am -
1 stop8h 10m
Deal found 11/6![United Airlines logo]()
$777
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:00 am -
2 stops13h 38m
Tue 12/158:55 am -
2 stops12h 01m
Deal found 11/6![United Airlines logo]()
$782
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:00 am -
1 stop14h 02m
Thu 12/1711:55 pm -
1 stop23h 14m
Deal found 11/6![United Airlines logo]()
$785
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/156:00 am -
2 stops13h 38m
Tue 12/2911:55 pm -
2 stops20h 52m
Deal found 11/7![United Airlines logo]()
$810
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:00 am -
1 stop14h 02m
Sun 12/1310:00 am -
1 stop10h 24m
Deal found 11/6![United Airlines logo]()
$811
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:00 am -
2 stops13h 38m
Thu 12/1711:55 pm -
2 stops14h 20m
Deal found 11/6![United Airlines logo]()
$816
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/305:58 pm -
2 stops20h 47m
Tue 12/158:55 am -
2 stops12h 01m
Deal found 11/6![United Airlines logo]()
$836
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:52 pm -
2 stops19h 21m
Wed 12/163:13 pm -
2 stops19h 27m
Deal found 11/6![American Airlines logo]()
$841
Best flights from Buffalo to Panama CityDiscover carefully curated flight deals from Buffalo to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 9, 2026.
Discover carefully curated flight deals from Buffalo to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 9, 2026.
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/2011:15 am -
1 stop8h 47m
Wed 2/38:55 am -
2 stops14h 04m
Deal found 11/8![United Airlines logo]()
$692
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/56:05 am -
1 stop7h 59m
Tue 1/123:29 pm -
1 stop8h 30m
Deal found 11/5![Delta logo]()
$697
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/611:15 am -
1 stop8h 47m
Wed 1/134:41 pm -
2 stops26h 51m
Deal found 11/4![United Airlines logo]()
$692
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/66:05 am -
1 stop7h 59m
Wed 1/133:29 pm -
1 stop8h 30m
Deal found 11/4![Delta logo]()
$697
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/195:50 am -
1 stop14h 12m
Tue 1/264:41 pm -
2 stops24h 00m
Deal found 11/5![United Airlines logo]()
$692
This Delta deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/86:05 am -
1 stop7h 59m
Wed 1/133:29 pm -
1 stop8h 30m
Deal found 11/8![Delta logo]()
$731
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/155:45 am -
1 stop14h 17m
Fri 1/2210:00 am -
1 stop9h 32m
Deal found 11/5![United Airlines logo]()
$755
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/135:30 pm -
1 stop11h 40m
Sun 3/2110:55 pm -
2 stops23h 52m
Deal found 11/5![United Airlines logo]()
$760
Last-minute flights from Buffalo to Panama CityDiscover last-minute flight deals from Buffalo to Panama City. Data last updated November 9, 2026 and is based on user searches.
Discover last-minute flight deals from Buffalo to Panama City. Data last updated November 9, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:00 am -
1 stop14h 02m
Mon 12/1410:00 am -
1 stop8h 10m
Deal found 11/6![United Airlines logo]()
$777
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:00 am -
1 stop14h 02m
Thu 12/1711:55 pm -
1 stop23h 14m
Deal found 11/6![United Airlines logo]()
$785
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:00 am -
1 stop14h 02m
Sun 12/1310:00 am -
1 stop10h 24m
Deal found 11/6![United Airlines logo]()
$811
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/305:58 pm -
2 stops20h 47m
Tue 12/158:55 am -
2 stops12h 01m
Deal found 11/6![United Airlines logo]()
$836
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:00 am -
2 stops13h 38m
Tue 12/158:55 am -
2 stops12h 01m
Deal found 11/6![United Airlines logo]()
$782
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:52 pm -
2 stops19h 21m
Wed 12/163:13 pm -
2 stops19h 27m
Deal found 11/6![American Airlines logo]()
$841
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:00 am -
2 stops13h 38m
Thu 12/1711:55 pm -
2 stops14h 20m
Deal found 11/6![United Airlines logo]()
$816
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/156:00 am -
2 stops13h 38m
Tue 12/2911:55 pm -
2 stops20h 52m
Deal found 11/7![United Airlines logo]()
$810
One-way flights from Buffalo to Panama CitySearch for one-way flight options from Buffalo to Panama City. Find affordable one-way fares based on user searches. Data last updated November 9, 2026.
Search for one-way flight options from Buffalo to Panama City. Find affordable one-way fares based on user searches. Data last updated November 9, 2026.
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/256:30 am -
2 stops13h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![United Airlines logo]()
$311
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/135:50 pm -
2 stops20h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![United Airlines logo]()
$345
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/259:38 pm -
3 stops22h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Multiple Airlines logo]()
$485
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/249:38 pm -
3 stops22h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Multiple Airlines logo]()
$525
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1311:23 am -
1 stop8h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![United Airlines logo]()
$533
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/139:38 pm -
3 stops35h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Multiple Airlines logo]()
$575
This KAYAK deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/136:30 am -
2 stops13h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Copa Airlines logo]()
$602
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/137:36 pm -
3 stops18h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![American Airlines logo]()
$2,336
Find flight deals from Buffalo to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $687 (United Airlines) |
One-way from | $311 (United Airlines) |
Popular in | August |
Cheapest in | June |
Cheapflights Fare Finder
Customize your flight search to find flights from Buffalo to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 9, 2026.
Use the filters below to find and compare flights from Buffalo to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
BuffaloPanama City
BUF Buffalo - PTY Panama City Tocumen Intl
BUFPTY
Buffalo
Thu 2/25
10:45 am-8:02 pm
1 stop9h 17m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$311
BuffaloPanama City
BUF Buffalo - PTY Panama City Tocumen Intl
BUFPTY
Buffalo
Wed 2/24
10:45 am-8:02 pm
1 stop9h 17m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$311
BuffaloPanama City
BUF Buffalo - PTY Panama City Tocumen Intl
BUFPTY
Buffalo
Sat 2/13
5:50 pm-2:45 pm
2 stops20h 55m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$345
BuffaloPanama City
BUF Buffalo - PTY Panama City Tocumen Intl
BUFPTY
Buffalo
Thu 2/25
9:38 pm-8:29 pm
3 stops22h 51m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$485
BuffaloPanama City
BUF Buffalo - PTY Panama City Tocumen Intl
BUFPTY
Buffalo
Wed 2/24
9:38 pm-7:45 pm
3 stops22h 07m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$525
Quickest round-trip
BuffaloPanama City
BUF Buffalo - PTY Panama City Tocumen Intl
BUFPTY
Buffalo
Sun 12/13
11:23 am-8:02 pm
1 stop8h 39m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$533
BuffaloPanama City
BUF Buffalo - PTY Panama City Tocumen Intl
BUFPTY
Buffalo
Wed 1/20
11:15 am-8:02 pm
1 stop8h 47m
Panama City Tocumen Intl
Wed 2/3
8:55 am-10:59 pm
2 stops14h 04m
$692
BuffaloPanama City
BUF Buffalo - PTY Panama City Tocumen Intl
BUFPTY
Buffalo
Wed 1/6
11:15 am-8:02 pm
1 stop8h 47m
Panama City Tocumen Intl
Wed 1/13
4:41 pm-7:32 pm
2 stops26h 51m
$692
BuffaloPanama City
BUF Buffalo - PTY Panama City Tocumen Intl
BUFPTY
Buffalo
Tue 1/19
5:50 am-8:02 pm
1 stop14h 12m
Panama City Tocumen Intl
Tue 1/26
4:41 pm-4:41 pm
2 stops24h 00m
$692
BuffaloPanama City
BUF Buffalo - PTY Panama City Tocumen Intl
BUFPTY
Buffalo
Tue 1/5
6:05 am-2:04 pm
1 stop7h 59m
Panama City Tocumen Intl
Tue 1/12
3:29 pm-11:59 pm
1 stop8h 30m
$697
Showing 1-10 of 14 resultsSorted by cheapest first
Compare providers for flights from Buffalo to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to Panama City in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Buffalo-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Buffalo-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Buffalo-Panama City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Buffalo-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Buffalo to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Buffalo with our price prediction graph.
BUF-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated November 9, 2026.
Read through reviews of airlines operating flights from Buffalo to Panama City, such as Delta. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Overall
7.8
Boarding
8.1
Food
7.2
Crew
8.5
Comfort
7.8
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Entertainment
7.8
Overall
7.8
Boarding
8.1
Food
7.2
Crew
8.5
Comfort
7.8
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Related info for your journey
Find useful and relevant information for your journey from Buffalo to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Buffalo
Panama City flight routes
Popular flights
Alternative routes for Buffalo to Panama City
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama City by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Buffalo to Panama City by cabin class
Find flights from Buffalo to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Buffalo and Panama City flights
Browse other Buffalo and Panama City flight options. Last updated on November 9, 2026.
Other flights from Buffalo
Browse through other flights departing from Buffalo. Flights are based on user searches made on Cheapflights and were last updated on November 9, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on November 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Buffalo to Panama City
Discover the top airline that operate flights from Buffalo to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$628 | Average$844 | FlexibilityNo cancel fee | On-timeN/A |