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Odessa

$359+ Cheap flights from St. Louis (STL) to Odessa, TX

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/19. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MAF
Mar 16 — Mar 231
Mon 3/16
Mon 3/23
1 adult, Economy
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Cheap flight deals from St. Louis to Odessa

Cheapest flights from St. Louis to Odessa
Explore the most affordable flight options available from St. Louis to Odessa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 14, 2026.

This Southwest deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/192:25 pm
STL
-
MAF
1 stop3h 45m
Southwest
Mon 3/236:40 pm
MAF
-
STL
1 stop5h 25m
Southwest
Deal found 2/12$359
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/265:30 am
STL
-
MAF
1 stop4h 35m
Southwest
Sun 3/16:20 am
MAF
-
STL
1 stop7h 55m
Southwest
Deal found 2/10$462
This Southwest deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/136:30 am
STL
-
MAF
1 stop8h 25m
Southwest
Fri 3/206:40 pm
MAF
-
STL
1 stop5h 25m
Southwest
Deal found 2/11$464
This United Airlines deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/38:41 am
STL
-
MAF
1 stop7h 38m
United Airlines
Wed 3/45:31 pm
MAF
-
STL
1 stop4h 43m
United Airlines
Deal found 2/12$537

Find flight deals from St. Louis to Odessa

Keep the following information in mind while searching for St. Louis to Odessa flight deals. Data was last updated February 14, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$359
(Southwest)
Provider with most accurate pricing for Lambert-St Louis-Midland Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Midland Intl flights.
Search Deals
From Lambert-St Louis to Odessa
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Odessa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 14, 2026.
Use the filters below to find and compare flights from St. Louis to Odessa that are best for you.

Fly from

St. Louis

Fly to

Odessa

Route

Depart

Return

Price

St. LouisMidland

STL - MAF

STLMAF

Lambert-St Louis

Thu 3/19

2:25 pm-6:10 pm

1 stop3h 45m

Midland Intl

Mon 3/23

6:40 pm-12:05 am

1 stop5h 25m

$359

St. LouisMidland

STL - MAF

STLMAF

Lambert-St Louis

Thu 2/26

5:30 am-10:05 am

1 stop4h 35m

Midland Intl

Sun 3/1

6:20 am-2:15 pm

1 stop7h 55m

$462

St. LouisMidland

STL - MAF

STLMAF

Lambert-St Louis

Fri 3/13

6:30 am-2:55 pm

1 stop8h 25m

Midland Intl

Fri 3/20

6:40 pm-12:05 am

1 stop5h 25m

$464

St. LouisMidland

STL - MAF

STLMAF

Lambert-St Louis

Tue 3/3

8:41 am-4:19 pm

1 stop7h 38m

Midland Intl

Wed 3/4

5:31 pm-10:14 pm

1 stop4h 43m

$537

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/12

Best time to book a flight from St. Louis to Odessa

Have a flexible travel schedule? Discover the best time to fly to Odessa from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Odessa
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Odessa

Get insights into the airlines that provide service to Odessa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Odessa. Reviews last updated February 14, 2026.
Read reviews from past customers who have flown Southwest and American Airlines from St. Louis to Odessa. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,286 reviews

Crew

8.6

Entertainment

7.5

Food

7.0

Boarding

8.1

Overall

8.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,286 reviews
Southwest
8.0
Very good
4,286 reviews

Crew

8.6

Entertainment

7.5

Food

7.0

Boarding

8.1

Overall

8.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,297 reviews
Southwest
8.0
Very good
4,286 reviews

Crew

8.6

Entertainment

7.5

Food

7.0

Boarding

8.1

Overall

8.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Odessa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Odessa?

    Located just 12.7 mi from the city center, Lambert-St Louis is the airport most travelers will use when flying to Odessa from St. Louis. Booking flights from Lambert-St Louis (STL) to Odessa should be relatively easy as there are 0 daily outbound flights to Odessa from 3 different airlines.

  • How long is the flight from St. Louis to Odessa?

    A quick flight from St. Louis to Odessa can take about 3h 45m. Southwest provides one of the quickest options available for as low as $359. St. Louis and Odessa are separated by a distance of 814 mi.

  • Can I find deals for flights from St. Louis to Odessa that include hotel bookings?

    Yes. In addition to deals on St. Louis to Odessa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Odessa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Odessa.

  • Can I find deals for business class flights from St. Louis to Odessa?

    Yes. Cheapflights offers flight deals from St. Louis to Odessa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top 3 airlines flying from St. Louis to Odessa

Discover the top 3 airlines that operate flights from St. Louis to Odessa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 14, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$196Average$312FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$233Average$333FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$290Average$367FlexibilityNo cancel feeOn-time63%

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