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Odessa

$196+ Cheap flights from St. Louis (STL) to Odessa, TX

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/11. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MAF
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from St. Louis to Odessa

Keep the following information in mind while searching for St. Louis to Odessa flight deals. Data was last updated September 15, 2025.

Round-trip from

$221
(United Airlines)

Popular in

January

Cheapest in

December
From Lambert-St Louis to Odessa
Search Deals
High demand for flights, 5% potential price rise
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($13 potential savings vs. average RT price).
Search Deals

Find flight deals from St. Louis to Odessa

Cheapest flights from St. Louis to Odessa
Explore the most affordable flight options available from St. Louis to Odessa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/111:45 pmSTL - MAF
2 stops8h 00mSouthwest
Sat 10/185:45 amMAF - STL
2 stops9h 05mSouthwest
Deal found 9/13$196
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/115:20 amSTL - MAF
1 stop4h 23mAmerican Airlines
Sat 10/182:25 pmMAF - STL
1 stop6h 28mAmerican Airlines
Deal found 9/13$197
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/95:15 amSTL - MAF
1 stop7h 42mUnited Airlines
Mon 10/133:30 pmMAF - STL
1 stop6h 30mUnited Airlines
Deal found 9/14$221
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/205:17 amSTL - MAF
1 stop4h 28mAmerican Airlines
Sun 11/236:05 amMAF - STL
1 stop4h 34mAmerican Airlines
Deal found 9/14$249
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/97:05 amSTL - MAF
2 stops9h 26mDelta
Mon 10/1312:33 pmMAF - STL
2 stops8h 55mDelta
Deal found 9/14$258
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/105:30 amSTL - MAF
1 stop4h 40mSouthwest
Fri 10/175:45 amMAF - STL
1 stop9h 10mSouthwest
Deal found 9/13$268
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/35:15 amSTL - MAF
1 stop7h 42mUnited Airlines
Mon 10/63:30 pmMAF - STL
1 stop6h 30mUnited Airlines
Deal found 9/13$315
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/37:10 amSTL - MAF
2 stops9h 30mDelta
Sun 10/512:33 pmMAF - STL
2 stops10h 51mDelta
Deal found 9/13$325

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Odessa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from St. Louis to Odessa that are best for you.

Fly from

St. Louis

Fly to

Odessa

Route

Depart

Return

Price

St. LouisMidland

STL - MAF

STLMAF

Lambert-St Louis

Sat 10/11

1:45 pm-9:45 pm

2 stops8h 00m

Midland Intl

Sat 10/18

5:45 am-2:50 pm

2 stops9h 05m

$196

St. LouisMidland

STL - MAF

STLMAF

Lambert-St Louis

Sat 10/11

5:20 am-9:43 am

1 stop4h 23m

Midland Intl

Sat 10/18

2:25 pm-8:53 pm

1 stop6h 28m

$197

St. LouisMidland

STL - MAF

STLMAF

Lambert-St Louis

Thu 10/9

5:15 am-12:57 pm

1 stop7h 42m

Midland Intl

Mon 10/13

3:30 pm-10:00 pm

1 stop6h 30m

$221

St. LouisMidland

STL - MAF

STLMAF

Lambert-St Louis

Thu 11/20

5:17 am-11:53 am

1 stop6h 36m

Midland Intl

Sun 11/23

7:55 am-12:37 pm

1 stop4h 42m

$249

St. LouisMidland

STL - MAF

STLMAF

Lambert-St Louis

Thu 10/9

7:05 am-4:31 pm

2 stops9h 26m

Midland Intl

Mon 10/13

12:33 pm-9:28 pm

2 stops8h 55m

$258

St. LouisMidland

STL - MAF

STLMAF

Lambert-St Louis

Fri 10/10

5:30 am-10:10 am

1 stop4h 40m

Midland Intl

Fri 10/17

5:45 am-2:55 pm

1 stop9h 10m

$268

St. LouisMidland

STL - MAF

STLMAF

Lambert-St Louis

Fri 10/3

12:25 pm-9:58 pm

2 stops9h 33m

Midland Intl

Mon 10/6

5:17 pm-11:58 pm

1 stop6h 41m

$320

St. LouisMidland

STL - MAF

STLMAF

Lambert-St Louis

Fri 10/3

7:10 am-4:40 pm

2 stops9h 30m

Midland Intl

Sun 10/5

12:33 pm-11:24 pm

2 stops10h 51m

$325

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Best time to book a flight from St. Louis to Odessa

Have a flexible travel schedule? Discover the best time to fly to Odessa from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Odessa

What is the cheapest time of day to fly from STL to OD3?

Find hourly flight availability from St. Louis to Odessa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from St. Louis to Odessa as you normally would.

Reviews of airlines servicing Odessa

Get insights into the airlines that provide service to Odessa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Odessa. Reviews last updated September 15, 2025.
Read reviews from past customers who have flown Southwest and American Airlines from St. Louis to Odessa. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Overall

8.0

Entertainment

7.5

Comfort

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Overall

8.0

Entertainment

7.5

Comfort

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,242 reviews

Overall

8.0

Entertainment

7.5

Comfort

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Odessa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Odessa?

    Located just 12.7 mi from the city center, Lambert-St Louis is the airport most travelers will use when flying to Odessa from St. Louis. Booking flights from Lambert-St Louis (STL) to Odessa should be relatively easy as there are 0 daily outbound flights to Odessa from 2 different airlines.

  • How long is the flight from St. Louis to Odessa?

    A quick flight from St. Louis to Odessa can take about 4h 23m. Southwest provides one of the quickest options available for as low as $197. St. Louis and Odessa are separated by a distance of 814 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from St. Louis to Odessa that include hotel bookings?

    Yes. In addition to deals on St. Louis to Odessa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Odessa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Odessa.

  • Can I find deals for business class flights from St. Louis to Odessa?

    Yes. Cheapflights offers flight deals from St. Louis to Odessa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Odessa?

    Currently, April is the cheapest month in which you can book a flight from St. Louis to Odessa (average of $336). Flying from St. Louis to Odessa in March is currently the most expensive (average of $389). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for St. Louis to Odessa

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Top 2 airlines flying from St. Louis to Odessa

Discover the top 2 airlines that operate flights from St. Louis to Odessa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$196Average$443FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$290Average$367FlexibilityNo cancel feeOn-time63%

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