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Odessa

$111+ Cheap flights from St. Louis (STL) to Odessa, TX

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/30. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MAF
Aug 23 — Aug 301
Sat 8/23
Sat 8/30
1 adult, Economy
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Cheap flight deals from St. Louis to Odessa

Keep the following information in mind while searching for St. Louis to Odessa flight deals. Data was last updated August 18, 2025.

Round-trip from

$239
(Southwest)

One-way from

$111
(American Airlines)

Popular in

January

Cheapest in

December
From Lambert-St Louis to Odessa
Search Deals
One-way flight from Lambert-St Louis to Odessa
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High demand for flights, 7% potential price rise
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Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
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Find flight deals from St. Louis to Odessa

Cheapest flights from St. Louis to Odessa
Explore the most affordable flight options available from St. Louis to Odessa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2025.

This Southwest deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/287:10 pmSTL - MAF
1 stop4h 55mSouthwest
Sun 11/27:40 pmMAF - STL
1 stop4h 40mSouthwest
Deal found 8/18$239
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/286:00 amSTL - MAF
2 stops7h 55mAmerican Airlines
Sun 11/25:00 amMAF - STL
1 stop5h 37mAmerican Airlines
Deal found 8/18$249
This Southwest deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2910:25 amSTL - MAF
2 stops5h 05mSouthwest
Sun 11/27:40 pmMAF - STL
1 stop4h 40mSouthwest
Deal found 8/15$264
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/281:30 pmSTL - MAF
2 stops10h 26mDelta
Sun 11/25:30 amMAF - STL
2 stops7h 05mDelta
Deal found 8/18$268
This Delta deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/296:00 amSTL - MAF
2 stops10h 31mDelta
Sun 11/25:30 amMAF - STL
2 stops7h 05mDelta
Deal found 8/15$298
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/298:49 amSTL - MAF
1 stop5h 06mAmerican Airlines
Sun 11/25:08 amMAF - STL
1 stop4h 29mAmerican Airlines
Deal found 8/18$314
This American Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/227:01 amSTL - MAF
1 stop7h 01mAmerican Airlines
Sun 8/242:30 pmMAF - STL
1 stop3h 59mAmerican Airlines
Deal found 8/15$409
This United Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/225:15 amSTL - MAF
1 stop7h 48mUnited Airlines
Sun 8/245:00 amMAF - STL
2 stops10h 44mUnited Airlines
Deal found 8/15$484

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Odessa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
Use the filters below to find and compare flights from St. Louis to Odessa that are best for you.

Fly from

St. Louis

Fly to

Odessa

Route

Depart

Return

Price

St. LouisMidland

STL - MAF

STLMAF

Lambert-St Louis

Tue 10/28

7:10 pm-12:05 am

1 stop4h 55m

Midland Intl

Sun 11/2

7:40 pm-12:20 am

1 stop4h 40m

$239

St. LouisMidland

STL - MAF

STLMAF

Lambert-St Louis

Wed 10/29

11:50 am-4:50 pm

1 stop5h 00m

Midland Intl

Sun 11/2

7:40 pm-12:20 am

1 stop4h 40m

$239

St. LouisMidland

STL - MAF

STLMAF

Lambert-St Louis

Tue 10/28

6:00 am-1:55 pm

2 stops7h 55m

Midland Intl

Sun 11/2

5:00 am-10:37 am

1 stop5h 37m

$249

St. LouisMidland

STL - MAF

STLMAF

Lambert-St Louis

Tue 10/28

1:30 pm-11:56 pm

2 stops10h 26m

Midland Intl

Sun 11/2

5:30 am-12:35 pm

2 stops7h 05m

$268

St. LouisMidland

STL - MAF

STLMAF

Lambert-St Louis

Wed 10/29

6:00 am-4:31 pm

2 stops10h 31m

Midland Intl

Sun 11/2

5:30 am-12:35 pm

2 stops7h 05m

$298

St. LouisMidland

STL - MAF

STLMAF

Lambert-St Louis

Wed 10/29

8:49 am-1:55 pm

1 stop5h 06m

Midland Intl

Sun 11/2

5:08 am-9:37 am

1 stop4h 29m

$314

St. LouisMidland

STL - MAF

STLMAF

Lambert-St Louis

Sat 8/30

5:15 am-9:39 am

1 stop4h 24m

$111

St. LouisMidland

STL - MAF

STLMAF

Lambert-St Louis

Sat 8/30

7:00 am-5:08 pm

2 stops10h 08m

$124

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/16

Best time to book a flight from St. Louis to Odessa

Have a flexible travel schedule? Discover the best time to fly to Odessa from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Odessa

What is the cheapest time of day to fly from STL to OD3?

Find hourly flight availability from St. Louis to Odessa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 18, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from St. Louis to Odessa as you normally would.

Reviews of airlines servicing Odessa

Get insights into the airlines that provide service to Odessa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Odessa. Reviews last updated August 18, 2025.
Read reviews from past customers who have flown Southwest and American Airlines from St. Louis to Odessa. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,246 reviews

Entertainment

7.5

Food

7.0

Boarding

8.1

Overall

8.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Southwest
8.0
Very good
4,246 reviews
Southwest
8.0
Very good
4,246 reviews

Entertainment

7.5

Food

7.0

Boarding

8.1

Overall

8.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,246 reviews

Entertainment

7.5

Food

7.0

Boarding

8.1

Overall

8.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Odessa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Odessa?

    Located just 12.7 mi from the city center, Lambert-St Louis is the airport most travelers will use when flying to Odessa from St. Louis. Booking flights from Lambert-St Louis (STL) to Odessa should be relatively easy as there are 0 daily outbound flights to Odessa from 2 different airlines.

  • How long is the flight from St. Louis to Odessa?

    A quick flight from St. Louis to Odessa can take about 4h 55m. Southwest provides one of the quickest options available for as low as $239. St. Louis and Odessa are separated by a distance of 814 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from St. Louis to Odessa that include hotel bookings?

    Yes. In addition to deals on St. Louis to Odessa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Odessa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Odessa.

  • Can I find deals for business class flights from St. Louis to Odessa?

    Yes. Cheapflights offers flight deals from St. Louis to Odessa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Odessa?

    Currently, April is the cheapest month in which you can book a flight from St. Louis to Odessa (average of $336). Flying from St. Louis to Odessa in March is currently the most expensive (average of $389). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from St. Louis to Odessa

Discover the top 2 airlines that operate flights from St. Louis to Odessa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$196Average$456FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$290Average$367FlexibilityNo cancel feeOn-time63%

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