How long is the flight from St. Louis to Odessa?

A quick flight from St. Louis to Odessa can take about 5h 14m. Southwest provides one of the quickest options available for as low as $392. St. Louis and Odessa are separated by a distance of 814 mi. This flight may include one or multiple stops.

In terms of precipitation, rainfall in Odessa ranges from 0.6 - 2.2 inches per month. September is typically the wettest month, when rainfall can reach 2.2 in. January is typically the driest time to visit Odessa when rainfall is around 0.6 in.

If weather is an important factor for your trip to Odessa, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 82.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

What airport do you fly from for flights from St. Louis to Odessa?

Located just 12.7 mi from the city center, Lambert-St Louis is the airport most travelers will use when flying to Odessa from St. Louis. Booking flights from Lambert-St Louis (STL) to Odessa should be relatively easy as there are 0 daily outbound flights to Odessa from 3 different airlines.

Can I find deals for flights from St. Louis to Odessa that include hotel bookings?

Yes. In addition to deals on St. Louis to Odessa flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from St. Louis to Odessa?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Odessa.

Can I find deals for business class flights from St. Louis to Odessa?

Yes. Cheapflights offers flight deals from St. Louis to Odessa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$239+ Flights from St. Louis to Odessa

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Find flight deals from St. Louis to Odessa

Cheapest flights from St. Louis to Odessa
Explore the most affordable flight options available from St. Louis to Odessa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 29, 2025.

Wed 12/242:30 pmSTL - MAF

1 stop7h 25mSouthwest

Mon 12/296:15 pmMAF - STL

1 stop5h 20mSouthwest

Deal found 11/27

$358

Sat 12/134:45 pmSTL - MAF

1 stop5h 14mUnited Airlines

Wed 12/171:55 pmMAF - STL

1 stop7h 02mUnited Airlines

Deal found 11/28

$392

Fri 12/197:00 amSTL - MAF

1 stop4h 43mAmerican Airlines

Mon 12/226:04 pmMAF - STL

1 stop4h 52mAmerican Airlines

Deal found 11/28

$407

Fri 12/199:50 amSTL - MAF

2 stops5h 15mSouthwest

Mon 12/223:45 pmMAF - STL

1 stop5h 10mSouthwest

Deal found 11/28

$430

Best flights from St. Louis to Odessa
Discover carefully curated flight deals from St. Louis to Odessa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 29, 2025.

Wed 12/242:30 pmSTL - MAF

1 stop7h 25mSouthwest

Mon 12/296:15 pmMAF - STL

1 stop5h 20mSouthwest

Deal found 11/27

$358

Sat 12/134:45 pmSTL - MAF

1 stop5h 14mUnited Airlines

Wed 12/171:55 pmMAF - STL

1 stop7h 02mUnited Airlines

Deal found 11/28

$392

Fri 12/197:00 amSTL - MAF

1 stop4h 43mAmerican Airlines

Mon 12/226:04 pmMAF - STL

1 stop4h 52mAmerican Airlines

Deal found 11/28

$407

Sat 12/137:35 amSTL - MAF

1 stop4h 50mSouthwest

Thu 12/187:15 amMAF - STL

1 stop6h 45mSouthwest

Deal found 11/29

$403

Fri 12/199:50 amSTL - MAF

2 stops5h 15mSouthwest

Mon 12/223:45 pmMAF - STL

1 stop5h 10mSouthwest

Deal found 11/28

$430

Last-minute flights from St. Louis to Odessa
Discover last-minute flight deals from St. Louis to Odessa. Data last updated November 29, 2025 and is based on user searches.

Sat 12/134:45 pmSTL - MAF

1 stop5h 14mUnited Airlines

Wed 12/171:55 pmMAF - STL

1 stop7h 02mUnited Airlines

Deal found 11/28

$392

Fri 12/197:00 amSTL - MAF

1 stop4h 43mAmerican Airlines

Mon 12/226:04 pmMAF - STL

1 stop4h 52mAmerican Airlines

Deal found 11/28

$407

Fri 12/199:50 amSTL - MAF

2 stops5h 15mSouthwest

Mon 12/223:45 pmMAF - STL

1 stop5h 10mSouthwest

Deal found 11/28

$430

Wed 12/242:30 pmSTL - MAF

1 stop7h 25mSouthwest

Mon 12/296:15 pmMAF - STL

1 stop5h 20mSouthwest

Deal found 11/27

$358

One-way flights from St. Louis to Odessa
Search for one-way flight options from St. Louis to Odessa. Find affordable one-way fares based on user searches. Data last updated November 29, 2025.

Tue 12/232:45 pmSTL - MAF

1 stop7h 14mUnited Airlines

Deal found 11/28

$239

Tue 12/235:16 amSTL - MAF

1 stop4h 33mAmerican Airlines

Deal found 11/27

$259

Cheap flight deals from St. Louis to Odessa

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$358 (Southwest)
One-way from	$239 (United Airlines)

Provider with most accurate pricing for Lambert-St Louis-Midland Intl flight deals.

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From Lambert-St Louis to Odessa

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One-way flight from Lambert-St Louis to Odessa

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Fly from

Fly to

Route

Depart

Return

Price

St. LouisMidland

STL - MAF

STLMAF

Lambert-St Louis

Wed 12/24

2:30 pm-9:55 pm

1 stop7h 25m

Midland Intl

Mon 12/29

6:15 pm-11:35 pm

1 stop5h 20m

$358

St. LouisMidland

STL - MAF

STLMAF

Lambert-St Louis

Sat 12/13

4:45 pm-9:59 pm

1 stop5h 14m

Midland Intl

Wed 12/17

1:55 pm-8:57 pm

1 stop7h 02m

$392

St. LouisMidland

STL - MAF

STLMAF

Lambert-St Louis

Sat 12/13

7:35 am-12:25 pm

1 stop4h 50m

Midland Intl

Thu 12/18

7:15 am-2:00 pm

1 stop6h 45m

$403

St. LouisMidland

STL - MAF

STLMAF

Lambert-St Louis

Fri 12/19

7:00 am-11:43 am

1 stop4h 43m

Midland Intl

Mon 12/22

6:04 pm-10:56 pm

1 stop4h 52m

$407

St. LouisMidland

STL - MAF

STLMAF

Lambert-St Louis

Fri 12/19

9:50 am-3:05 pm

2 stops5h 15m

Midland Intl

Mon 12/22

3:45 pm-8:55 pm

1 stop5h 10m

$430

St. LouisMidland

STL - MAF

STLMAF

Lambert-St Louis

Tue 12/23

2:45 pm-9:59 pm

1 stop7h 14m

$239

St. LouisMidland

STL - MAF

STLMAF

Lambert-St Louis

Tue 12/23

5:16 am-9:49 am

1 stop4h 33m

$259

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/28

Best time to book a flight from St. Louis to Odessa

Have a flexible travel schedule? Discover the best time to fly to Odessa from St. Louis with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Odessa

What is the cheapest time of day to fly from STL to OD3?

When flying from St. Louis to Odessa, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 36% versus a flight in the afternoon.

Reviews of airlines servicing Odessa

Read reviews from past customers who have flown Southwest and American Airlines from St. Louis to Odessa. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,255 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Southwest

8.0

Very good

4,255 reviews

Southwest

8.0

Very good

4,255 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

American Airlines

7.2

Good

11,044 reviews

Southwest

8.0

Very good

4,255 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

What airport do you fly from for flights from St. Louis to Odessa?
Located just 12.7 mi from the city center, Lambert-St Louis is the airport most travelers will use when flying to Odessa from St. Louis. Booking flights from Lambert-St Louis (STL) to Odessa should be relatively easy as there are 0 daily outbound flights to Odessa from 3 different airlines.
How long is the flight from St. Louis to Odessa?
A quick flight from St. Louis to Odessa can take about 5h 14m. Southwest provides one of the quickest options available for as low as $392. St. Louis and Odessa are separated by a distance of 814 mi. This flight may include one or multiple stops.
Can I find deals for flights from St. Louis to Odessa that include hotel bookings?
Yes. In addition to deals on St. Louis to Odessa flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from St. Louis to Odessa?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Odessa.
Can I find deals for business class flights from St. Louis to Odessa?
Yes. Cheapflights offers flight deals from St. Louis to Odessa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from St. Louis to Odessa

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$196	Average$339	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$233	Average$333	FlexibilityNo cancel fee	On-time69%
Southwest	Cheapest$290	Average$367	FlexibilityNo cancel fee	On-time63%

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$239+ Cheap flights from St. Louis (STL) to Odessa, TX

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/23. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from St. Louis to Odessa with Cheapflights

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Find flight deals from St. Louis to Odessa

Cheapest flights from St. Louis to OdessaExplore the most affordable flight options available from St. Louis to Odessa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 29, 2025.

Explore the most affordable flight options available from St. Louis to Odessa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 29, 2025.

Cheap flight deals from St. Louis to Odessa

Keep the following information in mind while searching for St. Louis to Odessa flight deals. Data was last updated November 29, 2025.

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Most trusted provider

Round-trip from

One-way from

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Use the filters below to find and compare flights from St. Louis to Odessa that are best for you.

Best time to book a flight from St. Louis to Odessa

Have a flexible travel schedule? Discover the best time to fly to Odessa from St. Louis with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Odessa

What is the cheapest time of day to fly from STL to OD3?

Find hourly flight availability from St. Louis to Odessa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 29, 2025.

Reviews of airlines servicing Odessa

Read reviews from past customers who have flown Southwest and American Airlines from St. Louis to Odessa. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Odessa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from St. Louis to Odessa?

How long is the flight from St. Louis to Odessa?

Can I find deals for flights from St. Louis to Odessa that include hotel bookings?

How can I find direct flights from St. Louis to Odessa?

Can I find deals for business class flights from St. Louis to Odessa?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for St. Louis to Odessa

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from St. Louis to Odessa

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Cheapest flights from St. Louis to Odessa
Explore the most affordable flight options available from St. Louis to Odessa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 29, 2025.