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Odessa

$350+ Cheap flights from Fort Myers (RSW) to Odessa, TX

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/2. Fares are subject to change and may not be available on all flights or dates of travel.
RSW — MAF
Nov 12 — Nov 191
Wed 11/12
Wed 11/19
1 adult, Economy
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Find flight deals from Fort Myers to Odessa

Cheapest flights from Fort Myers to Odessa
Explore the most affordable flight options available from Fort Myers to Odessa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 13, 2025.

This American Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/286:44 amRSW - MAF
1 stop8h 10mAmerican Airlines
Sun 11/306:05 amMAF - RSW
1 stop4h 57mAmerican Airlines
Deal found 10/13$659
This Southwest deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/286:40 amRSW - MAF
2 stops9h 10mSouthwest
Sun 11/306:00 amMAF - RSW
1 stop13h 15mSouthwest
Deal found 10/13$776

Cheap flight deals from Fort Myers to Odessa

Keep the following information in mind while searching for Fort Myers to Odessa flight deals. Data was last updated October 13, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$467
(American Airlines)

One-way from

$350
(United Airlines)
Provider with most accurate pricing for Fort Myers SW Florida Intl-Midland Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Fort Myers SW Florida Intl-Midland Intl flights.
Search Deals
From Fort Myers SW Florida Intl to Odessa
Search Deals
One-way flight from Fort Myers SW Florida Intl to Odessa
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Fort Myers to Odessa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 13, 2025.
Use the filters below to find and compare flights from Fort Myers to Odessa that are best for you.

Fly from

Fort Myers

Fly to

Odessa

Route

Depart

Return

Price

Fort MyersMidland

RSW - MAF

RSWMAF

Fort Myers SW Florida Intl

Tue 3/31

7:41 pm-11:45 pm

1 stop5h 04m

Midland Intl

Wed 4/1

5:03 am-11:41 am

1 stop5h 38m

$467

Fort MyersMidland

RSW - MAF

RSWMAF

Fort Myers SW Florida Intl

Fri 11/28

6:44 am-1:54 pm

1 stop8h 10m

Midland Intl

Sun 11/30

6:05 am-12:02 pm

1 stop4h 57m

$659

Fort MyersMidland

RSW - MAF

RSWMAF

Fort Myers SW Florida Intl

Fri 11/28

6:40 am-2:50 pm

2 stops9h 10m

Midland Intl

Sun 11/30

6:00 am-8:15 pm

1 stop13h 15m

$776

Fort MyersMidland

RSW - MAF

RSWMAF

Fort Myers SW Florida Intl

Fri 1/2

5:08 pm-11:25 pm

1 stop7h 17m

$350

Fort MyersMidland

RSW - MAF

RSWMAF

Fort Myers SW Florida Intl

Sun 1/4

7:15 pm-11:58 pm

1 stop5h 43m

$400

Fort MyersMidland

RSW - MAF

RSWMAF

Fort Myers SW Florida Intl

Fri 1/2

8:10 am-5:34 pm

2 stops10h 24m

$429

Fort MyersMidland

RSW - MAF

RSWMAF

Fort Myers SW Florida Intl

Sat 1/3

4:30 pm-12:10 am

2 stops8h 40m

$449

Fort MyersMidland

RSW - MAF

RSWMAF

Fort Myers SW Florida Intl

Sat 1/3

6:37 am-9:59 pm

3 stops16h 22m

$3,149

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/11

Best time to book a flight from Fort Myers to Odessa

Have a flexible travel schedule? Discover the best time to fly to Odessa from Fort Myers with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Fort Myers to Odessa

What is the cheapest time of day to fly from RSW to OD3?

Find hourly flight availability from Fort Myers to Odessa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 13, 2025.

A simple way to save on the total cost of your ticket is to fly from Fort Myers to Odessa in the evening. If you’re flexible enough to do this you can expect to save up to 26% on your trip compared to booking a flight in the afternoon.

Reviews of airlines servicing Odessa

Get insights into the airlines that provide service to Odessa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Odessa. Reviews last updated October 13, 2025.
Peruse reviews from past customers who have flown with United Airlines and American Airlines from Fort Myers to Odessa to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,974 reviews

Overall

7.4

Comfort

7.3

Entertainment

7.1

Boarding

7.7

Crew

8.1

Food

6.6

Reviews

1 / 20
8.0
Excellent

FERNANDO,Sep 2024

YYC - IAH

Everything was good, maybe can give better foof flys more than 4 hours
United Airlines
7.4
Good
8,974 reviews
United Airlines
7.4
Good
8,974 reviews

Overall

7.4

Comfort

7.3

Entertainment

7.1

Boarding

7.7

Crew

8.1

Food

6.6

Reviews

1 / 20
8.0
Excellent

FERNANDO,Sep 2024

YYC - IAH

Everything was good, maybe can give better foof flys more than 4 hours
American Airlines
7.2
Good
11,045 reviews
United Airlines
7.4
Good
8,974 reviews

Overall

7.4

Comfort

7.3

Entertainment

7.1

Boarding

7.7

Crew

8.1

Food

6.6

Reviews

1 / 20
8.0
Excellent

FERNANDO,Sep 2024

YYC - IAH

Everything was good, maybe can give better foof flys more than 4 hours

Related info for your journey

Find useful and relevant information for your journey from Fort Myers to Odessa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Fort Myers to Odessa?

    Located just 10.0 mi from the city center, Fort Myers SW Florida Intl is the airport most travelers will use when flying to Odessa from Fort Myers. Booking flights from SW Florida Intl (RSW) to Odessa should be relatively easy as there are 0 daily outbound flights to Odessa from 2 different airlines.

  • How long is the flight from Fort Myers to Odessa?

    For as low as $467, American Airlines can have you in Odessa from Fort Myers in 5h 04m. Airlines will cover a distance of 1285 mi.

  • Can I find deals for flights from Fort Myers to Odessa that include hotel bookings?

    Yes. In addition to deals on Fort Myers to Odessa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Fort Myers to Odessa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Odessa.

  • Can I find deals for business class flights from Fort Myers to Odessa?

    Yes. Cheapflights offers flight deals from Fort Myers to Odessa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top 2 airlines flying from Fort Myers to Odessa

Discover the top 2 airlines that operate flights from Fort Myers to Odessa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$296Average$416FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$411Average$416FlexibilityNo cancel feeOn-time69%

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