$151+ Cheap flights from San Francisco to Panama City, FL (SFO - ECP)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/5. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — ECP
Sep 4 — Sep 111
Round-trip
1 adult, Economy
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Find cheap flights from San Francisco to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Francisco to Panama City
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Best
Last-minute
One-way
Cheapest flights from San Francisco to Panama CityExplore the most affordable flight options available from San Francisco to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 5, 2026.
Explore the most affordable flight options available from San Francisco to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 5, 2026.
This American Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:25 am -
1 stop8h 08m
Sat 9/512:25 pm -
1 stop7h 24m
Deal found 8/1![American Airlines logo]()
$313
This Southwest deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:00 am -
2 stops11h 10m
Sat 9/511:45 am -
1 stop6h 40m
Deal found 8/1![Southwest logo]()
$318
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/257:05 am -
1 stop7h 33m
Wed 8/2611:41 am -
1 stop7h 16m
Deal found 8/3![United Airlines logo]()
$325
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:35 am -
2 stops10h 10m
Wed 8/2610:30 am -
2 stops8h 50m
Deal found 8/3![Southwest logo]()
$335
This Delta deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:00 pm -
1 stop8h 18m
Mon 9/146:20 pm -
1 stop7h 37m
Deal found 8/2![Delta logo]()
$340
This Southwest deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/59:40 am -
2 stops9h 50m
Mon 11/95:55 pm -
1 stop7h 25m
Deal found 8/1![Southwest logo]()
$357
This American Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/285:30 am -
1 stop6h 40m
Wed 9/26:40 am -
1 stop9h 57m
Deal found 8/1![American Airlines logo]()
$361
This Southwest deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:40 am -
2 stops9h 35m
Sat 9/198:15 am -
2 stops8h 30m
Deal found 8/2![Southwest logo]()
$362
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2911:40 pm -
2 stops10h 55m
Wed 9/97:45 am -
1 stop10h 40m
Deal found 8/3![Southwest logo]()
$363
This Southwest deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2811:05 pm -
1 stop7h 55m
Wed 9/21:00 pm -
2 stops10h 40m
Deal found 8/1![Southwest logo]()
$366
Best flights from San Francisco to Panama CityDiscover carefully curated flight deals from San Francisco to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 5, 2026.
Discover carefully curated flight deals from San Francisco to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 5, 2026.
This Southwest deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:00 am -
2 stops11h 10m
Sat 9/511:45 am -
1 stop6h 40m
Deal found 8/1![Southwest logo]()
$318
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/257:05 am -
1 stop7h 33m
Wed 8/2611:41 am -
1 stop7h 16m
Deal found 8/3![United Airlines logo]()
$325
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:55 pm -
1 stop8h 21m
Sun 11/15:36 pm -
1 stop8h 20m
Deal found 7/31![Delta logo]()
$396
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:35 am -
2 stops10h 10m
Wed 8/2610:30 am -
2 stops8h 50m
Deal found 8/3![Southwest logo]()
$335
This Southwest deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:50 am -
2 stops10h 00m
Fri 9/1111:20 am -
1 stop9h 55m
Deal found 8/1![Southwest logo]()
$361
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/17:05 am -
1 stop7h 33m
Sat 9/51:47 pm -
1 stop9h 23m
Deal found 8/1![United Airlines logo]()
$423
This Southwest deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/285:10 am -
2 stops11h 50m
Wed 9/21:00 pm -
2 stops10h 40m
Deal found 8/1![Southwest logo]()
$371
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:00 am -
1 stop7h 17m
Tue 12/810:25 am -
1 stop8h 56m
Deal found 8/4![United Airlines logo]()
$435
This Southwest deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/135:40 am -
2 stops7h 35m
Mon 2/2210:05 am -
2 stops11h 55m
Deal found 8/2![Southwest logo]()
$406
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2111:05 pm -
1 stop7h 55m
Sat 8/2911:45 am -
2 stops9h 50m
Deal found 8/3![Southwest logo]()
$461
Last-minute flights from San Francisco to Panama CityDiscover last-minute flight deals from San Francisco to Panama City. Data last updated August 5, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Panama City. Data last updated August 5, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/257:05 am -
1 stop7h 33m
Wed 8/2611:41 am -
1 stop7h 16m
Deal found 8/3![United Airlines logo]()
$325
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:35 am -
2 stops10h 10m
Wed 8/2610:30 am -
2 stops8h 50m
Deal found 8/3![Southwest logo]()
$335
This American Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/285:30 am -
1 stop6h 40m
Wed 9/26:40 am -
1 stop9h 57m
Deal found 8/1![American Airlines logo]()
$361
This Southwest deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2811:05 pm -
1 stop7h 55m
Wed 9/21:00 pm -
2 stops10h 40m
Deal found 8/1![Southwest logo]()
$366
This American Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:25 am -
1 stop8h 08m
Sat 9/512:25 pm -
1 stop7h 24m
Deal found 8/1![American Airlines logo]()
$313
This Southwest deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:00 am -
2 stops11h 10m
Sat 9/511:45 am -
1 stop6h 40m
Deal found 8/1![Southwest logo]()
$318
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2911:40 pm -
2 stops10h 55m
Wed 9/97:45 am -
1 stop10h 40m
Deal found 8/3![Southwest logo]()
$363
This Delta deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:00 pm -
1 stop8h 18m
Mon 9/146:20 pm -
1 stop7h 37m
Deal found 8/2![Delta logo]()
$340
This Southwest deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:40 am -
2 stops9h 35m
Sat 9/198:15 am -
2 stops8h 30m
Deal found 8/2![Southwest logo]()
$362
One-way flights from San Francisco to Panama CitySearch for one-way flight options from San Francisco to Panama City. Find affordable one-way fares based on user searches. Data last updated August 5, 2026.
Search for one-way flight options from San Francisco to Panama City. Find affordable one-way fares based on user searches. Data last updated August 5, 2026.
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/511:15 pm -
1 stop7h 16m
Deal found 8/5![Delta logo]()
$151
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/68:20 am -
2 stops10h 15m
Deal found 8/5![Southwest logo]()
$156
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am -
1 stop7h 31m
Deal found 8/5![Delta logo]()
$163
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/317:55 pm -
2 stops11h 45m
Deal found 8/3![Southwest logo]()
$168
This Southwest deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:45 am -
2 stops11h 55m
Deal found 8/1![Southwest logo]()
$174
This United Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/612:35 am -
1 stop10h 31m
Deal found 8/5![United Airlines logo]()
$218
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/49:55 pm -
1 stop8h 21m
Deal found 8/1![Delta logo]()
$234
This Southwest deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/411:25 am -
2 stops9h 00m
Deal found 8/1![Southwest logo]()
$239
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/82:30 pm -
2 stops15h 46m
Deal found 8/5![Delta logo]()
$267
This Southwest deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/229:00 am -
2 stops9h 50m
Deal found 8/2![Southwest logo]()
$280
Find flight deals from San Francisco to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $313 (American Airlines) |
One-way from | $151 (Delta) |
Popular in | December |
Cheapest in | January |
Average price | $411 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 5, 2026.
Use the filters below to find and compare flights from San Francisco to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Sat 8/29
5:00 am-6:10 pm
2 stops11h 10m
Panama City NW Florida Beaches
Sat 9/5
11:45 am-4:25 pm
1 stop6h 40m
$318
Quickest round-trip
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Tue 8/25
7:05 am-4:38 pm
1 stop7h 33m
Panama City NW Florida Beaches
Wed 8/26
11:41 am-4:57 pm
1 stop7h 16m
$325
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Tue 8/25
6:35 am-6:45 pm
2 stops10h 10m
Panama City NW Florida Beaches
Wed 8/26
10:30 am-5:20 pm
2 stops8h 50m
$335
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Tue 9/8
6:50 am-6:50 pm
2 stops10h 00m
Panama City NW Florida Beaches
Fri 9/11
11:20 am-7:15 pm
1 stop9h 55m
$361
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Fri 8/28
5:10 am-7:00 pm
2 stops11h 50m
Panama City NW Florida Beaches
Wed 9/2
1:00 pm-9:40 pm
2 stops10h 40m
$371
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Thu 10/1
9:55 pm-8:16 am
1 stop8h 21m
Panama City NW Florida Beaches
Sun 11/1
5:36 pm-11:56 pm
1 stop8h 20m
$396
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Wed 1/13
5:40 am-3:15 pm
2 stops7h 35m
Panama City NW Florida Beaches
Mon 2/22
10:05 am-8:00 pm
2 stops11h 55m
$406
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Tue 9/1
7:05 am-4:38 pm
1 stop7h 33m
Panama City NW Florida Beaches
Sat 9/5
1:47 pm-9:10 pm
1 stop9h 23m
$423
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Sat 12/5
5:00 am-2:17 pm
1 stop7h 17m
Panama City NW Florida Beaches
Tue 12/8
10:25 am-5:21 pm
1 stop8h 56m
$435
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Fri 8/21
11:05 pm-9:00 am
1 stop7h 55m
Panama City NW Florida Beaches
Sat 8/29
11:45 am-7:35 pm
2 stops9h 50m
$461
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from San Francisco to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Panama City in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Francisco-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Panama City, Florida flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Francisco-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Francisco to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from San Francisco with our price prediction graph.
SFO-ECP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Panama City
What is the cheapest month to book a flight from San Francisco to Panama City, Florida?
Currently, January is the cheapest month in which you can book a flight from San Francisco to Panama City, Florida (average of $342). Flying from San Francisco to Panama City, Florida in December is currently the most expensive (average of $1,001). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Francisco to Panama City, Florida?
Airfare is below average for this route at the moment.
San Francisco to Panama City, Florida flights typically cost between $378 and $527 in August.The cheapest round-trip price found within the last 5 days was $313 on American Airlines (Aug 29-Sep 5).
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated August 5, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from San Francisco to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Comfort
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Comfort
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Comfort
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Comfort
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Panama City?
Book flights to Panama City if you plan to visit one of these locationsMexico Beach
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San Francisco and Panama City flights
Browse other San Francisco and Panama City flight options. Last updated on August 5, 2026.
Other flights from San Francisco
Browse through other flights departing from San Francisco. Flights are based on user searches made on Cheapflights and were last updated on August 5, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from San Francisco to Panama City
Discover the top 4 airlines that operate flights from San Francisco to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$300 | Average$485 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$371 | Average$508 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$378 | Average$494 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$425 | Average$536 | FlexibilityNo cancel fee | On-time71% |