$200+ Cheap flights from San Francisco to Panama City, FL (SFO - ECP)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/8. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — ECP
Jun 9 — Jun 161
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Francisco to Panama City
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Best
Last-minute
One-way
Cheapest flights from San Francisco to Panama CityExplore the most affordable flight options available from San Francisco to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 10, 2026.
Explore the most affordable flight options available from San Francisco to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 10, 2026.
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/271:45 pm
SFO
- ECP
1 stop7h 16m
Delta
Thu 5/286:45 pm
ECP
- SFO
1 stop8h 01m
Delta
Deal found 5/5![Delta logo]()
$397
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:15 am
SFO
- ECP
1 stop8h 11m
American Airlines
Mon 6/84:51 pm
ECP
- SFO
1 stop8h 30m
American Airlines
Deal found 5/6![American Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/2310:59 pm
SFO
- ECP
1 stop7h 15m
Delta
Wed 6/242:46 pm
ECP
- SFO
1 stop10h 03m
Delta
Deal found 5/8![Delta logo]()
$405
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2711:59 pm
SFO
- ECP
1 stop8h 55m
Delta
Wed 7/111:43 am
ECP
- SFO
1 stop10h 11m
Delta
Deal found 5/10![Delta logo]()
$408
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/2310:59 pm
SFO
- ECP
1 stop7h 15m
Delta
Mon 6/293:54 pm
ECP
- SFO
1 stop18h 59m
Delta
Deal found 5/8![Delta logo]()
$412
This Southwest deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2111:15 am
SFO
- ECP
1 stop8h 20m
Southwest
Wed 9/309:10 am
ECP
- SFO
2 stops11h 05m
Southwest
Deal found 5/9![Southwest logo]()
$413
This Southwest deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2210:50 pm
SFO
- ECP
1 stop9h 25m
Southwest
Thu 10/2910:55 am
ECP
- SFO
1 stop12h 40m
Southwest
Deal found 5/9![Southwest logo]()
$426
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/288:25 am
SFO
- ECP
1 stop8h 44m
Delta
Fri 5/294:54 pm
ECP
- SFO
1 stop9h 52m
Delta
Deal found 5/5![Delta logo]()
$428
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:00 am
SFO
- ECP
1 stop8h 37m
Delta
Thu 5/282:50 pm
ECP
- SFO
1 stop9h 58m
Delta
Deal found 5/5![Delta logo]()
$429
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/410:30 pm
SFO
- ECP
1 stop7h 44m
Delta
Wed 7/85:07 pm
ECP
- SFO
1 stop7h 42m
Delta
Deal found 5/8![Delta logo]()
$431
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/169:40 pm
SFO
- ECP
1 stop10h 30m
Southwest
Mon 10/196:30 am
ECP
- SFO
2 stops11h 20m
Southwest
Deal found 5/6![Southwest logo]()
$433
Best flights from San Francisco to Panama CityDiscover carefully curated flight deals from San Francisco to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 10, 2026.
Discover carefully curated flight deals from San Francisco to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 10, 2026.
This Southwest deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/217:55 pm
SFO
- ECP
2 stops11h 45m
Southwest
Wed 9/309:10 am
ECP
- SFO
2 stops9h 45m
Southwest
Deal found 5/9![Southwest logo]()
$418
This Delta deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:00 am
SFO
- ECP
1 stop7h 25m
Delta
Sun 8/169:27 am
ECP
- SFO
1 stop7h 20m
Delta
Deal found 5/6![Delta logo]()
$457
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1410:50 pm
SFO
- ECP
1 stop8h 40m
Southwest
Mon 7/206:55 am
ECP
- SFO
2 stops8h 25m
Southwest
Deal found 5/8![Southwest logo]()
$431
This Southwest deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/110:50 pm
SFO
- ECP
1 stop9h 25m
Southwest
Sun 10/49:55 am
ECP
- SFO
1 stop6h 30m
Southwest
Deal found 5/9![Southwest logo]()
$449
This Southwest deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/610:50 pm
SFO
- ECP
1 stop8h 40m
Southwest
Fri 7/102:55 pm
ECP
- SFO
1 stop7h 25m
Southwest
Deal found 5/9![Southwest logo]()
$457
This Southwest deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/711:15 am
SFO
- ECP
1 stop8h 20m
Southwest
Fri 9/114:10 pm
ECP
- SFO
1 stop7h 45m
Southwest
Deal found 5/9![Southwest logo]()
$457
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/311:00 am
SFO
- ECP
2 stops9h 00m
Southwest
Mon 7/66:55 am
ECP
- SFO
2 stops13h 45m
Southwest
Deal found 5/8![Southwest logo]()
$473
Last-minute flights from San Francisco to Panama CityDiscover last-minute flight deals from San Francisco to Panama City. Data last updated May 10, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Panama City. Data last updated May 10, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:00 am
SFO
- ECP
1 stop8h 37m
Delta
Thu 5/282:50 pm
ECP
- SFO
1 stop9h 58m
Delta
Deal found 5/5![Delta logo]()
$429
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/271:45 pm
SFO
- ECP
1 stop7h 16m
Delta
Thu 5/286:45 pm
ECP
- SFO
1 stop8h 01m
Delta
Deal found 5/5![Delta logo]()
$397
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2711:20 am
SFO
- ECP
1 stop9h 41m
Delta
Fri 5/294:54 pm
ECP
- SFO
1 stop9h 52m
Delta
Deal found 5/5![Delta logo]()
$426
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/288:25 am
SFO
- ECP
1 stop8h 44m
Delta
Fri 5/294:54 pm
ECP
- SFO
1 stop9h 52m
Delta
Deal found 5/5![Delta logo]()
$428
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:15 am
SFO
- ECP
1 stop8h 11m
American Airlines
Mon 6/84:51 pm
ECP
- SFO
1 stop8h 30m
American Airlines
Deal found 5/6![American Airlines logo]()
$399
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/110:55 pm
SFO
- ECP
1 stop8h 35m
Southwest
Mon 6/85:55 pm
ECP
- SFO
2 stops8h 35m
Southwest
Deal found 5/6![Southwest logo]()
$434
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2011:59 pm
SFO
- ECP
1 stop8h 55m
Delta
Wed 6/242:46 pm
ECP
- SFO
1 stop10h 03m
Delta
Deal found 5/8![Delta logo]()
$436
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2011:59 pm
SFO
- ECP
1 stop8h 55m
Delta
Mon 6/293:54 pm
ECP
- SFO
1 stop18h 59m
Delta
Deal found 5/8![Delta logo]()
$443
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/2310:59 pm
SFO
- ECP
1 stop7h 15m
Delta
Tue 6/309:19 am
ECP
- SFO
1 stop9h 48m
Delta
Deal found 5/8![Delta logo]()
$405
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/2310:59 pm
SFO
- ECP
1 stop7h 15m
Delta
Mon 6/293:54 pm
ECP
- SFO
1 stop18h 59m
Delta
Deal found 5/8![Delta logo]()
$412
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2711:59 pm
SFO
- ECP
1 stop8h 55m
Delta
Wed 7/111:43 am
ECP
- SFO
1 stop10h 11m
Delta
Deal found 5/10![Delta logo]()
$408
One-way flights from San Francisco to Panama CitySearch for one-way flight options from San Francisco to Panama City. Find affordable one-way fares based on user searches. Data last updated May 10, 2026.
Search for one-way flight options from San Francisco to Panama City. Find affordable one-way fares based on user searches. Data last updated May 10, 2026.
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/810:50 pm
SFO
- ECP
1 stop8h 40m
Southwest
Deal found 5/6![Southwest logo]()
$200
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/99:56 pm
SFO
- ECP
1 stop8h 21m
Delta
Deal found 5/9![Delta logo]()
$211
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/911:24 am
SFO
- ECP
1 stop9h 11m
American Airlines
Deal found 5/5![American Airlines logo]()
$229
This Delta deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/309:56 pm
SFO
- ECP
1 stop8h 21m
Delta
Deal found 5/7![Delta logo]()
$234
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/67:05 am
SFO
- ECP
2 stops9h 55m
Southwest
Deal found 5/7![Southwest logo]()
$244
This Southwest deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/125:40 am
SFO
- ECP
2 stops10h 45m
Southwest
Deal found 5/9![Southwest logo]()
$275
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/810:59 pm
SFO
- ECP
2 stops15h 24m
United Airlines
Deal found 5/6![United Airlines logo]()
$409
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1512:59 am
SFO
- ECP
1 stop19h 14m
American Airlines
Deal found 5/6![American Airlines logo]()
$422
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/3010:59 pm
SFO
- ECP
2 stops15h 24m
United Airlines
Deal found 5/6![United Airlines logo]()
$428
Find flight deals from San Francisco to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $397 (Delta) |
One-way from | $200 (Southwest) |
Popular in | December |
Cheapest in | August |
Average price | $512 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 10, 2026.
Use the filters below to find and compare flights from San Francisco to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Mon 9/21
7:55 pm-9:40 am
2 stops11h 45m
Panama City NW Florida Beaches
Wed 9/30
9:10 am-4:55 pm
2 stops9h 45m
$418
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Tue 7/14
10:50 pm-9:30 am
1 stop8h 40m
Panama City NW Florida Beaches
Mon 7/20
6:55 am-1:20 pm
2 stops8h 25m
$431
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Thu 10/1
10:50 pm-10:15 am
1 stop9h 25m
Panama City NW Florida Beaches
Sun 10/4
9:55 am-2:25 pm
1 stop6h 30m
$449
Quickest round-trip
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Mon 8/10
6:00 am-3:25 pm
1 stop7h 25m
Panama City NW Florida Beaches
Sun 8/16
9:27 am-2:47 pm
1 stop7h 20m
$457
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Mon 7/6
10:50 pm-9:30 am
1 stop8h 40m
Panama City NW Florida Beaches
Fri 7/10
2:55 pm-8:20 pm
1 stop7h 25m
$457
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Mon 9/7
11:15 am-9:35 pm
1 stop8h 20m
Panama City NW Florida Beaches
Fri 9/11
4:10 pm-9:55 pm
1 stop7h 45m
$457
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Fri 7/3
11:00 am-10:00 pm
2 stops9h 00m
Panama City NW Florida Beaches
Mon 7/6
6:55 am-6:40 pm
2 stops13h 45m
$473
Cheapest one-way
Quickest one-way
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Thu 7/30
9:56 pm-8:17 am
1 stop8h 21m
$211
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Thu 7/9
9:56 pm-8:17 am
1 stop8h 21m
$211
San FranciscoPanama City
SFO - ECP
SFOECP
San Francisco
Sat 6/6
7:05 am-7:00 pm
2 stops9h 55m
$244
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from San Francisco to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Panama City in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Francisco-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Panama City, Florida flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Francisco-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Francisco to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from San Francisco with our price prediction graph.
SFO-ECP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Panama City
What is the cheapest month to book a flight from San Francisco to Panama City, Florida?
Currently, August is the cheapest month in which you can book a flight from San Francisco to Panama City, Florida (average of $325). Flying from San Francisco to Panama City, Florida in December is currently the most expensive (average of $819). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Francisco to Panama City, Florida?
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated May 10, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from San Francisco to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Overall
8.0
Boarding
8.1
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Food
7.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Overall
8.0
Boarding
8.1
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Food
7.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Overall
8.0
Boarding
8.1
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Food
7.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Overall
8.0
Boarding
8.1
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Food
7.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Overall
8.0
Boarding
8.1
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Related info for your journey
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Book flights to Panama City if you plan to visit one of these locationsMexico Beach
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Top 4 airlines flying from San Francisco to Panama City
Discover the top 4 airlines that operate flights from San Francisco to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$287 | Average$457 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$326 | Average$571 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$342 | Average$485 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$437 | Average$527 | FlexibilityNo cancel fee | On-time63% |