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Panama City

$185+ Cheap flights from San Francisco to Panama City, FL (SFO - ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/6. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — ECP
Feb 26 — Mar 51
Thu 2/26
Thu 3/5
1 adult, Economy
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Cheap flight deals from San Francisco to Panama City

Cheapest flights from San Francisco to Panama City
Explore the most affordable flight options available from San Francisco to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.

This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:00 am
SFO
-
ECP
1 stop7h 08m
American Airlines
Mon 3/164:34 pm
ECP
-
SFO
1 stop8h 36m
American Airlines
Deal found 1/27$385
This Southwest deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/245:35 pm
SFO
-
ECP
2 stops14h 10m
Southwest
Tue 3/38:00 am
ECP
-
SFO
2 stops12h 05m
Southwest
Deal found 1/25$395
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/1612:30 am
SFO
-
ECP
2 stops11h 00m
American Airlines
Wed 2/1812:38 pm
ECP
-
SFO
2 stops12h 36m
American Airlines
Deal found 1/25$396
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1911:25 pm
SFO
-
ECP
1 stop10h 10m
Southwest
Wed 4/223:00 pm
ECP
-
SFO
1 stop9h 10m
Southwest
Deal found 1/27$398
This Delta deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/155:59 pm
SFO
-
ECP
1 stop18h 37m
Delta
Tue 5/192:47 pm
ECP
-
SFO
1 stop8h 48m
Delta
Deal found 1/25$402
This Delta deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/62:05 pm
SFO
-
ECP
1 stop6h 34m
Delta
Thu 3/124:23 pm
ECP
-
SFO
1 stop10h 12m
Delta
Deal found 1/25$411
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/1512:25 am
SFO
-
ECP
1 stop7h 41m
American Airlines
Tue 2/173:00 pm
ECP
-
SFO
1 stop10h 47m
American Airlines
Deal found 1/25$412
This Southwest deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/68:35 am
SFO
-
ECP
2 stops10h 00m
Southwest
Mon 3/94:30 pm
ECP
-
SFO
1 stop8h 50m
Southwest
Deal found 1/25$416

Find flight deals from San Francisco to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$385
(American Airlines)

One-way from

$185
(Southwest)

Popular in

December

Cheapest in

August

Average price

$342
Provider with most accurate pricing for San Francisco-Panama City NW Florida Beaches flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Francisco-Panama City NW Florida Beaches flights.
Search Deals
From San Francisco to Panama City NW Florida Beaches
Search Deals
One-way flight from San Francisco to Panama City NW Florida Beaches
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($73 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($28 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from San Francisco to Panama City that are best for you.

Fly from

San Francisco

Fly to

Panama City

Route

Depart

Return

Price

San FranciscoPanama City

SFO - ECP

SFOECP

San Francisco

Tue 2/24

7:18 am-4:11 pm

1 stop6h 53m

Panama City NW Florida Beaches

Tue 3/3

6:30 am-2:57 pm

1 stop10h 27m

$385

San FranciscoPanama City

SFO - ECP

SFOECP

San Francisco

Tue 3/3

6:00 am-3:08 pm

1 stop7h 08m

Panama City NW Florida Beaches

Mon 3/16

4:34 pm-11:10 pm

1 stop8h 36m

$385

San FranciscoPanama City

SFO - ECP

SFOECP

San Francisco

Mon 3/9

8:00 am-7:27 pm

1 stop9h 27m

Panama City NW Florida Beaches

Thu 3/12

4:23 pm-12:35 am

1 stop10h 12m

$385

San FranciscoPanama City

SFO - ECP

SFOECP

San Francisco

Tue 4/14

6:20 am-5:45 pm

1 stop9h 25m

Panama City NW Florida Beaches

Sat 4/18

11:05 am-4:20 pm

1 stop7h 15m

$385

San FranciscoPanama City

SFO - ECP

SFOECP

San Francisco

Tue 5/12

6:20 am-6:55 pm

2 stops10h 35m

Panama City NW Florida Beaches

Tue 5/19

7:55 am-5:30 pm

2 stops11h 35m

$395

San FranciscoPanama City

SFO - ECP

SFOECP

San Francisco

Sun 4/19

11:25 pm-11:35 am

1 stop10h 10m

Panama City NW Florida Beaches

Wed 4/22

3:00 pm-10:10 pm

1 stop9h 10m

$398

San FranciscoPanama City

SFO - ECP

SFOECP

San Francisco

Mon 4/6

11:59 pm-9:35 am

1 stop7h 36m

Panama City NW Florida Beaches

Fri 4/10

6:30 am-2:53 pm

1 stop10h 23m

$411

San FranciscoPanama City

SFO - ECP

SFOECP

San Francisco

Sun 3/8

11:35 pm-10:23 am

1 stop8h 48m

Panama City NW Florida Beaches

Thu 3/12

4:23 pm-12:35 am

1 stop10h 12m

$411

San FranciscoPanama City

SFO - ECP

SFOECP

San Francisco

Fri 3/6

10:45 pm-9:43 am

1 stop8h 58m

Panama City NW Florida Beaches

Mon 3/9

2:10 pm-9:26 pm

1 stop9h 16m

$411

San FranciscoPanama City

SFO - ECP

SFOECP

San Francisco

Sun 2/15

12:25 am-10:06 am

1 stop7h 41m

Panama City NW Florida Beaches

Tue 2/17

3:00 pm-11:47 pm

1 stop10h 47m

$412

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/24

Showing 1-10 of 20 results
1
2

Compare providers for flights from San Francisco to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Panama City in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Francisco-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Panama City, Florida flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Francisco-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Francisco to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Panama City

What is the cheapest month to book a flight from San Francisco to Panama City, Florida?

Currently, January is the cheapest month in which you can book a flight from San Francisco to Panama City, Florida (average of $102). Flying from San Francisco to Panama City, Florida in December is currently the most expensive (average of $388). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated January 27, 2026.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from San Francisco to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,268 reviews

Boarding

8.1

Comfort

8.0

Overall

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
Southwest
8.0
Very good
4,268 reviews
Southwest
8.0
Very good
4,268 reviews

Boarding

8.1

Comfort

8.0

Overall

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
Delta
7.9
Good
8,118 reviews
Southwest
8.0
Very good
4,268 reviews

Boarding

8.1

Comfort

8.0

Overall

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
United Airlines
7.4
Good
9,205 reviews
Southwest
8.0
Very good
4,268 reviews

Boarding

8.1

Comfort

8.0

Overall

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
American Airlines
7.2
Good
11,197 reviews
Southwest
8.0
Very good
4,268 reviews

Boarding

8.1

Comfort

8.0

Overall

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Francisco to Panama City, Florida?

    A quick flight from San Francisco to Panama City, Florida can take about 6h 53m. United Airlines provides one of the quickest options available for as low as $385. Airlines will cover a distance of 2139 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from San Francisco to Panama City, Florida round-trip?

    According to our current data, Delta ($287), American Airlines ($342), and United Airlines ($342) offers the cheapest pricing from San Francisco to Panama City, Florida. Delta is priced at 44% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest airlines to fly from San Francisco to Panama City, Florida one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $123. American Airlines flights start at $153 while deals on United Airlines start at $179 one-way.

  • Can I find deals for flights from San Francisco to Panama City that include hotel bookings?

    Yes. In addition to deals on San Francisco to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Panama City.

  • Can I find deals for business class flights from San Francisco to Panama City?

    Yes. Cheapflights offers flight deals from San Francisco to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Panama City, Florida?

    Currently, January is the cheapest month in which you can book a flight from San Francisco to Panama City, Florida (average of $102). Flying from San Francisco to Panama City, Florida in December is currently the most expensive (average of $388). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
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Top 4 airlines flying from San Francisco to Panama City

Discover the top 4 airlines that operate flights from San Francisco to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$287Average$436FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$342Average$492FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$342Average$496FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$416Average$502FlexibilityNo cancel feeOn-time63%

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