$163+ Cheap flights from San Francisco to Panama City, FL (SFO - ECP)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/18. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — ECP
Dec 3 — Dec 101
Round-trip
1 adult, Economy
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Find cheap flights from San Francisco to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Francisco to Panama City
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Best
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Cheapest flights from San Francisco to Panama CityExplore the most affordable flight options available from San Francisco to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 3, 2026.
Explore the most affordable flight options available from San Francisco to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 3, 2026.
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1110:59 pm -
1 stop9h 35m
Thu 12/174:06 pm -
1 stop9h 53m
Deal found 10/29![Delta logo]()
$345
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/118:00 am -
2 stops10h 35m
Thu 12/177:00 am -
2 stops10h 10m
Deal found 10/29![Southwest logo]()
$389
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1310:59 pm -
1 stop7h 39m
Tue 12/151:38 pm -
1 stop7h 23m
Deal found 11/1![Delta logo]()
$412
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2911:15 pm -
1 stop9h 37m
Sat 12/59:05 am -
1 stop7h 59m
Deal found 10/29![United Airlines logo]()
$423
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/198:20 pm -
2 stops11h 00m
Fri 12/2510:05 am -
2 stops13h 20m
Deal found 11/1![Southwest logo]()
$467
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/247:00 am -
2 stops9h 15m
Mon 1/47:00 am -
2 stops10h 30m
Deal found 11/3![Southwest logo]()
$474
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/112:45 am -
1 stop9h 21m
Thu 12/31:30 pm -
1 stop7h 17m
Deal found 11/1![United Airlines logo]()
$507
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/256:05 am -
1 stop7h 21m
Wed 1/611:03 am -
1 stop9h 50m
Deal found 11/3![Delta logo]()
$518
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/256:30 am -
2 stops24h 07m
Thu 1/711:03 am -
1 stop8h 21m
Deal found 11/3![Delta logo]()
$520
Best flights from San Francisco to Panama CityDiscover carefully curated flight deals from San Francisco to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 3, 2026.
Discover carefully curated flight deals from San Francisco to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 3, 2026.
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1110:59 pm -
1 stop9h 35m
Thu 12/174:06 pm -
1 stop9h 53m
Deal found 10/29![Delta logo]()
$345
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/118:00 am -
2 stops10h 35m
Thu 12/177:00 am -
2 stops10h 10m
Deal found 10/29![Southwest logo]()
$389
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2911:15 pm -
1 stop9h 37m
Sat 12/59:05 am -
1 stop7h 59m
Deal found 10/29![United Airlines logo]()
$423
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/166:00 am -
1 stop8h 40m
Wed 2/246:00 am -
1 stop9h 25m
Deal found 11/1![Delta logo]()
$377
This Southwest deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/118:40 pm -
2 stops13h 45m
Mon 2/156:00 pm -
2 stops8h 30m
Deal found 10/31![Southwest logo]()
$455
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1711:45 pm -
1 stop6h 32m
Tue 5/42:47 pm -
1 stop8h 48m
Deal found 11/2![Delta logo]()
$451
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/175:00 am -
2 stops10h 05m
Tue 5/42:40 pm -
1 stop9h 20m
Deal found 11/1![Southwest logo]()
$456
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1311:59 pm -
1 stop6h 39m
Tue 12/1511:22 am -
2 stops10h 56m
Deal found 11/1![Delta logo]()
$470
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/177:00 am -
1 stop7h 17m
Tue 5/46:30 am -
1 stop7h 48m
Deal found 11/2![United Airlines logo]()
$581
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/297:10 pm -
2 stops12h 10m
Sat 12/510:05 am -
1 stop7h 05m
Deal found 10/29![Southwest logo]()
$558
Last-minute flights from San Francisco to Panama CityDiscover last-minute flight deals from San Francisco to Panama City. Data last updated November 3, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Panama City. Data last updated November 3, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/411:30 pm -
1 stop6h 44m
Mon 11/94:11 pm -
1 stop9h 47m
Deal found 10/29![Delta logo]()
$780
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1311:15 pm -
1 stop9h 37m
Tue 11/173:05 pm -
1 stop8h 41m
Deal found 10/29![United Airlines logo]()
$754
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/145:00 am -
1 stop7h 28m
Wed 11/184:55 pm -
2 stops17h 10m
Deal found 10/29![United Airlines logo]()
$700
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1610:53 am -
1 stop8h 43m
Fri 11/2011:30 am -
1 stop9h 15m
Deal found 11/1![United Airlines logo]()
$757
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2911:15 pm -
1 stop9h 37m
Sat 12/59:05 am -
1 stop7h 59m
Deal found 10/29![United Airlines logo]()
$423
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/297:10 pm -
2 stops12h 10m
Sat 12/510:05 am -
1 stop7h 05m
Deal found 10/29![Southwest logo]()
$558
One-way flights from San Francisco to Panama CitySearch for one-way flight options from San Francisco to Panama City. Find affordable one-way fares based on user searches. Data last updated November 3, 2026.
Search for one-way flight options from San Francisco to Panama City. Find affordable one-way fares based on user searches. Data last updated November 3, 2026.
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:59 pm -
1 stop6h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Delta logo]()
$163
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:10 am -
2 stops10h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Southwest logo]()
$202
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/1010:25 pm -
1 stop8h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/31![Delta logo]()
$224
This Southwest deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:45 pm -
2 stops11h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/31![Southwest logo]()
$225
This Southwest deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/106:40 am -
2 stops9h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/31![Southwest logo]()
$229
This Southwest deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2410:40 am -
2 stops10h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/31![Southwest logo]()
$280
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:00 am -
1 stop9h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![United Airlines logo]()
$284
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:00 am -
1 stop7h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![United Airlines logo]()
$311
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/232:05 pm -
1 stop7h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/31![Delta logo]()
$330
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/145:30 am -
2 stops10h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Southwest logo]()
$369
Find flight deals from San Francisco to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $345 (Delta) |
One-way from | $163 (Delta) |
Popular in | October |
Cheapest in | January |
Average price | $418 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 3, 2026.
Use the filters below to find and compare flights from San Francisco to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San FranciscoPanama City
SFO San Francisco - ECP Panama City NW Florida Beaches
SFOECP
San Francisco
Mon 2/8
11:00 pm-9:45 am
1 stop8h 45m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$189
San FranciscoPanama City
SFO San Francisco - ECP Panama City NW Florida Beaches
SFOECP
San Francisco
Sun 1/10
10:25 pm-8:39 am
1 stop8h 14m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$224
San FranciscoPanama City
SFO San Francisco - ECP Panama City NW Florida Beaches
SFOECP
San Francisco
Tue 4/20
1:05 pm-10:25 pm
1 stop7h 20m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$226
San FranciscoPanama City
SFO San Francisco - ECP Panama City NW Florida Beaches
SFOECP
San Francisco
Sun 1/10
6:40 am-6:05 pm
2 stops9h 25m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$229
San FranciscoPanama City
SFO San Francisco - ECP Panama City NW Florida Beaches
SFOECP
San Francisco
Tue 11/24
10:40 am-10:40 pm
2 stops10h 00m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$280
San FranciscoPanama City
SFO San Francisco - ECP Panama City NW Florida Beaches
SFOECP
San Francisco
Tue 11/24
5:00 am-4:18 pm
1 stop9h 18m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$284
Quickest round-trip
San FranciscoPanama City
SFO San Francisco - ECP Panama City NW Florida Beaches
SFOECP
San Francisco
Wed 11/11
2:05 pm-11:24 pm
1 stop7h 19m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$311
San FranciscoPanama City
SFO San Francisco - ECP Panama City NW Florida Beaches
SFOECP
San Francisco
Wed 11/18
5:00 am-2:28 pm
1 stop7h 28m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$311
San FranciscoPanama City
SFO San Francisco - ECP Panama City NW Florida Beaches
SFOECP
San Francisco
Sat 11/21
10:45 pm-9:35 am
1 stop8h 50m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$314
San FranciscoPanama City
SFO San Francisco - ECP Panama City NW Florida Beaches
SFOECP
San Francisco
Wed 11/11
5:05 am-3:10 pm
2 stops8h 05m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$316
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from San Francisco to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Panama City in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Francisco-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Panama City, Florida flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Francisco-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Francisco to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from San Francisco with our price prediction graph.
SFO-ECP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Panama City
What is the cheapest month to book a flight from San Francisco to Panama City, Florida?
Currently, January is the cheapest month in which you can book a flight from San Francisco to Panama City, Florida (average of $342). Flying from San Francisco to Panama City, Florida in October is currently the most expensive (average of $683). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Francisco to Panama City, Florida?
Airfare is below average for this route at the moment.
San Francisco to Panama City, Florida flights typically cost between $352 and $599 in December.The cheapest round-trip price found within the last 5 days was $345 on Delta (Dec 11-Dec 17).
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated November 3, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from San Francisco to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Overall
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Overall
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Overall
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Overall
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Overall
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Complete your trip
Complete your trip to Panama City by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from San Francisco to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Francisco and Panama City flights
Browse other San Francisco and Panama City flight options. Last updated on November 3, 2026.
Other flights from San Francisco
Browse through other flights departing from San Francisco. Flights are based on user searches made on Cheapflights and were last updated on November 3, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on November 3, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from San Francisco to Panama City
Discover the top 4 airlines that operate flights from San Francisco to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$336 | Average$492 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$336 | Average$411 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$378 | Average$494 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$406 | Average$531 | FlexibilityNo cancel fee | On-time71% |