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Panama City

$149+ Cheap flights from San Francisco to Panama City, FL (SFO - ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/29. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — ECP
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from San Francisco to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2025.

Round-trip from

$297
(United Airlines)

One-way from

$149
(Delta)

Popular in

January

Cheapest in

August

Average price

$529
From San Francisco to Panama City NW Florida Beaches
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One-way flight from San Francisco to Panama City NW Florida Beaches
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Highest demand for flights based on searches. 10% potential increase in price ($58 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from San Francisco to Panama City

Cheapest flights from San Francisco to Panama City
Explore the most affordable flight options available from San Francisco to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1412:43 amSFO - ECP
1 stop7h 09mUnited Airlines
Wed 10/225:08 pmECP - SFO
1 stop7h 12mUnited Airlines
Deal found 9/17$297
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/37:15 amSFO - ECP
1 stop7h 32mAmerican Airlines
Wed 12/106:33 amECP - SFO
2 stops11h 30mAmerican Airlines
Deal found 9/16$302
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1111:59 pmSFO - ECP
2 stops9h 30mAmerican Airlines
Thu 11/1311:04 amECP - SFO
1 stop8h 50mAmerican Airlines
Deal found 9/16$306
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/107:15 amSFO - ECP
1 stop8h 00mAmerican Airlines
Fri 11/146:47 amECP - SFO
1 stop10h 16mAmerican Airlines
Deal found 9/16$326
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1111:56 pmSFO - ECP
1 stop8h 17mAmerican Airlines
Mon 10/207:16 pmECP - SFO
1 stop7h 01mAmerican Airlines
Deal found 9/15$357
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/231:45 pmSFO - ECP
1 stop7h 25mDelta
Mon 10/276:17 pmECP - SFO
1 stop7h 48mDelta
Deal found 9/16$367
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/155:09 amSFO - ECP
1 stop7h 57mAmerican Airlines
Wed 10/226:31 amECP - SFO
1 stop8h 40mAmerican Airlines
Deal found 9/16$396

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from San Francisco to Panama City that are best for you.

Fly from

San Francisco

Fly to

Panama City

Route

Depart

Return

Price

San FranciscoPanama City

SFO - ECP

SFOECP

San Francisco

Tue 11/11

8:00 am-7:16 pm

1 stop9h 16m

Panama City NW Florida Beaches

Thu 11/13

2:37 pm-9:25 pm

1 stop8h 48m

$307

San FranciscoPanama City

SFO - ECP

SFOECP

San Francisco

Tue 10/14

12:43 am-9:52 am

1 stop7h 09m

Panama City NW Florida Beaches

Wed 10/22

11:10 am-5:46 pm

1 stop8h 36m

$397

San FranciscoPanama City

SFO - ECP

SFOECP

San Francisco

Wed 10/1

1:00 pm-9:48 pm

1 stop6h 48m

Panama City NW Florida Beaches

Tue 10/28

5:00 pm-12:12 am

1 stop9h 12m

$417

San FranciscoPanama City

SFO - ECP

SFOECP

San Francisco

Wed 10/1

11:59 pm-9:52 am

1 stop7h 53m

Panama City NW Florida Beaches

Wed 10/29

5:00 pm-10:59 pm

1 stop7h 59m

$417

San FranciscoPanama City

SFO - ECP

SFOECP

San Francisco

Wed 10/15

12:43 am-9:52 am

1 stop7h 09m

Panama City NW Florida Beaches

Mon 10/20

5:08 pm-11:57 pm

1 stop8h 49m

$421

San FranciscoPanama City

SFO - ECP

SFOECP

San Francisco

Fri 10/3

12:43 am-9:52 am

1 stop7h 09m

Panama City NW Florida Beaches

Sat 11/1

2:22 pm-9:13 pm

1 stop8h 51m

$427

San FranciscoPanama City

SFO - ECP

SFOECP

San Francisco

Sat 10/4

10:50 am-9:48 pm

1 stop8h 58m

Panama City NW Florida Beaches

Fri 10/31

6:30 am-12:10 pm

1 stop7h 40m

$436

San FranciscoPanama City

SFO - ECP

SFOECP

San Francisco

Wed 10/29

1:45 pm-11:10 pm

1 stop7h 25m

$149

San FranciscoPanama City

SFO - ECP

SFOECP

San Francisco

Wed 11/12

7:15 am-4:44 pm

1 stop7h 29m

$149

San FranciscoPanama City

SFO - ECP

SFOECP

San Francisco

Tue 10/14

12:43 am-9:52 am

1 stop7h 09m

$199

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 12 results
1
2

Best time to book a flight from San Francisco to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Panama City

What is the cheapest month to book a flight from San Francisco to Panama City, Florida?

Currently, January is the cheapest month in which you can book a flight from San Francisco to Panama City, Florida (average of $346). Flying from San Francisco to Panama City, Florida in March is currently the most expensive (average of $459). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to ECP?

Find hourly flight availability from San Francisco to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

A simple way to save on the total cost of your ticket is to fly from San Francisco to Panama City, Florida in the afternoon. If you’re flexible enough to do this you can expect to save up to 39% on your trip compared to booking a flight in the evening.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 17, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from San Francisco to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Crew

8.6

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Crew

8.6

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Delta
8.0
Very good
7,961 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Crew

8.6

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
United Airlines
7.4
Good
8,926 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Crew

8.6

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Crew

8.6

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Francisco to Panama City, Florida?

    A quick flight from San Francisco to Panama City, Florida can take about 7h 09m. American Airlines provides one of the quickest options available for as low as $397. Airlines will cover a distance of 2139 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from San Francisco to Panama City, Florida round-trip?

    According to our current data, Delta ($306), American Airlines ($326), and United Airlines ($379) offers the cheapest pricing from San Francisco to Panama City, Florida. Delta is priced at 38% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from San Francisco to Panama City that include hotel bookings?

    Yes. In addition to deals on San Francisco to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Panama City.

  • Can I find deals for business class flights from San Francisco to Panama City?

    Yes. Cheapflights offers flight deals from San Francisco to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Panama City, Florida?

    Currently, January is the cheapest month in which you can book a flight from San Francisco to Panama City, Florida (average of $346). Flying from San Francisco to Panama City, Florida in March is currently the most expensive (average of $459). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
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Top 4 airlines flying from San Francisco to Panama City

Discover the top 4 airlines that operate flights from San Francisco to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$306Average$446FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$326Average$495FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$379Average$521FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$411Average$576FlexibilityNo cancel feeOn-time63%

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