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$693+ Cheap flights from Bruxelles-National (BRU) to Panama City, FL (ECP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/16. Fares are subject to change and may not be available on all flights or dates of travel.
BRU — ECP
Jan 22 — Jan 291
Thu 1/22
Thu 1/29
1 adult, Economy
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Cheap flight deals from Bruxelles-National to Panama City

Best flights from Bruxelles-National to Panama City
Discover carefully curated flight deals from Bruxelles-National to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 23, 2025.

This American Airlines deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/1611:45 amBRU - ECP
2 stops40h 34mAmerican Airlines
Mon 1/1912:03 pmECP - BRU
2 stops39h 47mAmerican Airlines
Deal found 12/20$693

Find flight deals from Bruxelles-National to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Bruxelles-National (BRU) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 23, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
1 star

Round-trip from

$693
(American Airlines)
Provider with most accurate pricing for Brussels Bruxelles-National-Panama City NW Florida Beaches flight deals.
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Provider most trusted by Cheapflights users for Brussels Bruxelles-National-Panama City NW Florida Beaches flights.
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From Brussels Bruxelles-National to Panama City NW Florida Beaches
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Bruxelles-National to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
Use the filters below to find and compare flights from Brussels Bruxelles-National Airport to Panama City that are best for you.

Fly from

Bruxelles-National

Fly to

Panama City

Route

Depart

Return

Price

BrusselsPanama City

BRU - ECP

BRUECP

Brussels Bruxelles-National

Fri 1/16

11:45 am-9:19 pm

2 stops40h 34m

Panama City NW Florida Beaches

Mon 1/19

12:03 pm-10:50 am

2 stops39h 47m

$693

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/20

  • Most accurate provider: When it comes to deals on Brussels Bruxelles-National Airport-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Brussels Bruxelles-National Airport-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Brussels Bruxelles-National Airport-Panama City, Florida flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Brussels Bruxelles-National Airport-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Brussels Bruxelles-National Airport-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Bruxelles-National to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Bruxelles-National with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Bruxelles-National to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Brussels Bruxelles-National?

    Most people fly into Panama City NW Florida Beaches (ECP) if they book a flight to Panama City from Brussels Bruxelles-National. On average, NW Florida Beaches has 0 inbound flights from Brussels Bruxelles-National per day from 0 airlines. Panama City NW Florida Beaches is conveniently located just 16.0 mi from Panama City’s city center.

  • How long is the flight from Brussels Bruxelles-National Airport to Panama City, Florida?

    For as low as $693, American Airlines can have you in Panama City, Florida from Brussels Bruxelles-National Airport in 40h 34m. Airlines will cover a distance of 4631 mi.

  • Can I find deals for flights from Bruxelles-National to Panama City that include hotel bookings?

    Yes. In addition to deals on Bruxelles-National to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Bruxelles-National to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Bruxelles-National to Panama City.

  • Can I find deals for business class flights from Bruxelles-National to Panama City?

    Yes. Cheapflights offers flight deals from Bruxelles-National to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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