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$609+ Cheap flights from Bruxelles-National (BRU) to Panama City, FL (ECP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/23. Fares are subject to change and may not be available on all flights or dates of travel.
BRU — ECP
Feb 6 — Feb 131
Fri 2/6
Fri 2/13
1 adult, Economy
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Cheap flight deals from Bruxelles-National to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Bruxelles-National (BRU) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 7, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
1 star

Round-trip from

$618
(KLM)
Provider with most accurate pricing for Brussels Bruxelles-National-Panama City NW Florida Beaches flight deals.
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Provider most trusted by Cheapflights users for Brussels Bruxelles-National-Panama City NW Florida Beaches flights.
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From Brussels Bruxelles-National to Panama City NW Florida Beaches
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Find flight deals from Bruxelles-National to Panama City

Cheapest flights from Bruxelles-National to Panama City
Explore the most affordable flight options available from Bruxelles-National to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 7, 2026.

This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2310:55 amBRU - ECP
2 stops53h 50mAmerican Airlines
Sun 9/273:53 pmECP - BRU
2 stops21h 32mAmerican Airlines
Deal found 1/6$609
This KLM deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/236:15 amBRU - ECP
2 stops17h 57mKLM
Tue 1/277:20 amECP - BRU
2 stops17h 15mKLM
Deal found 1/7$618
This United Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2010:30 amBRU - ECP
2 stops36h 42mUnited Airlines
Fri 2/276:30 amECP - BRU
2 stops41h 45mUnited Airlines
Deal found 1/6$644
This United Airlines deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/49:40 amBRU - ECP
2 stops43h 19mUnited Airlines
Sat 4/114:57 pmECP - BRU
2 stops31h 18mUnited Airlines
Deal found 1/7$660
This United Airlines deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2310:15 amBRU - ECP
2 stops16h 51mUnited Airlines
Sun 9/272:15 pmECP - BRU
1 stop11h 45mUnited Airlines
Deal found 1/5$978
This Delta deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/49:45 amBRU - ECP
1 stop17h 07mDelta
Sat 4/1111:50 amECP - BRU
2 stops19h 50mDelta
Deal found 1/7$1,025
This KLM deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/49:45 amBRU - ECP
1 stop17h 07mKLM
Sat 4/115:30 pmECP - BRU
1 stop31h 10mKLM
Deal found 1/7$1,135
This Scandinavian Airlines deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Scandinavian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/410:20 amBRU - ECP
2 stops19h 44mScandinavian Airlines
Sat 4/111:30 pmECP - BRU
3 stops21h 50mScandinavian Airlines
Deal found 1/7$2,439
This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2011:45 amBRU - ECP
3 stops19h 04mAmerican Airlines
Fri 2/274:34 pmECP - BRU
2 stops17h 46mAmerican Airlines
Deal found 1/6$4,496

Cheapflights Fare Finder

 
Customize your flight search to find flights from Bruxelles-National to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 7, 2026.
Use the filters below to find and compare flights from Brussels Bruxelles-National Airport to Panama City that are best for you.

Fly from

Bruxelles-National

Fly to

Panama City

Route

Depart

Return

Price

BrusselsPanama City

BRU - ECP

BRUECP

Brussels Bruxelles-National

Fri 1/23

6:15 am-5:12 pm

2 stops17h 57m

Panama City NW Florida Beaches

Tue 1/27

7:20 am-7:35 am

2 stops17h 15m

$618

BrusselsPanama City

BRU - ECP

BRUECP

Brussels Bruxelles-National

Fri 2/20

10:30 am-4:12 pm

2 stops36h 42m

Panama City NW Florida Beaches

Fri 2/27

6:30 am-7:15 am

2 stops41h 45m

$644

BrusselsPanama City

BRU - ECP

BRUECP

Brussels Bruxelles-National

Sat 4/4

9:40 am-9:59 pm

2 stops43h 19m

Panama City NW Florida Beaches

Sat 4/11

4:57 pm-7:15 am

2 stops31h 18m

$660

BrusselsPanama City

BRU - ECP

BRUECP

Brussels Bruxelles-National

Sat 4/4

9:45 am-7:52 pm

1 stop17h 07m

Panama City NW Florida Beaches

Sat 4/11

11:50 am-2:40 pm

2 stops19h 50m

$1,025

BrusselsPanama City

BRU - ECP

BRUECP

Brussels Bruxelles-National

Sat 4/4

9:45 am-7:52 pm

1 stop17h 07m

Panama City NW Florida Beaches

Sat 4/11

5:30 pm-7:40 am

1 stop31h 10m

$1,135

BrusselsPanama City

BRU - ECP

BRUECP

Brussels Bruxelles-National

Sat 4/4

10:20 am-11:04 pm

2 stops19h 44m

Panama City NW Florida Beaches

Sat 4/11

1:30 pm-6:20 pm

3 stops21h 50m

$2,439

BrusselsPanama City

BRU - ECP

BRUECP

Brussels Bruxelles-National

Fri 2/20

11:45 am-11:49 pm

3 stops19h 04m

Panama City NW Florida Beaches

Fri 2/27

4:34 pm-5:20 pm

2 stops17h 46m

$4,496

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/7

  • Most accurate provider: When it comes to deals on Brussels Bruxelles-National Airport-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Brussels Bruxelles-National Airport-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Brussels Bruxelles-National Airport-Panama City, Florida flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Brussels Bruxelles-National Airport-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Brussels Bruxelles-National Airport-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Bruxelles-National to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Bruxelles-National with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Bruxelles-National to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Brussels Bruxelles-National?

    Most people fly into Panama City NW Florida Beaches (ECP) if they book a flight to Panama City from Brussels Bruxelles-National. On average, NW Florida Beaches has 0 inbound flights from Brussels Bruxelles-National per day from 0 airlines. Panama City NW Florida Beaches is conveniently located just 16.0 mi from Panama City’s city center.

  • How long is the flight from Brussels Bruxelles-National Airport to Panama City, Florida?

    For as low as $1,025, KLM can have you in Panama City, Florida from Brussels Bruxelles-National Airport in 17h 07m. Airlines will cover a distance of 4631 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Bruxelles-National to Panama City that include hotel bookings?

    Yes. In addition to deals on Bruxelles-National to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Bruxelles-National to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Bruxelles-National to Panama City.

  • Can I find deals for business class flights from Bruxelles-National to Panama City?

    Yes. Cheapflights offers flight deals from Bruxelles-National to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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