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Panama City

$621+ Cheap flights from Bruxelles-National (BRU) to Panama City, FL (ECP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/30. Fares are subject to change and may not be available on all flights or dates of travel.
BRU — ECP
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Bruxelles-National to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Bruxelles-National (BRU) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2025.

Round-trip from

$621
(American Airlines)
From Brussels Bruxelles-National to Panama City NW Florida Beaches
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Find flight deals from Bruxelles-National to Panama City

Cheapest flights from Bruxelles-National to Panama City
Explore the most affordable flight options available from Bruxelles-National to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/305:30 pmBRU - ECP
2 stops30h 45mAmerican Airlines
Thu 11/62:37 pmECP - BRU
2 stops19h 23mAmerican Airlines
Deal found 9/15$621
This Scandinavian Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Scandinavian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/3010:20 amBRU - ECP
2 stops18h 50mScandinavian Airlines
Thu 11/65:00 pmECP - BRU
3 stops20h 55mScandinavian Airlines
Deal found 9/15$940
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1712:00 pmBRU - ECP
2 stops32h 03mUnited Airlines
Thu 9/251:55 pmECP - BRU
1 stop12h 05mUnited Airlines
Deal found 9/14$6,051
This FlightHub deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/174:00 pmBRU - ECP
2 stops38h 03mScandinavian Airlines
Thu 9/252:05 pmECP - BRU
2 stops22h 45mScandinavian Airlines
Deal found 9/15$6,952
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/177:05 amBRU - ECP
2 stops21h 07mAmerican Airlines
Thu 9/256:59 pmECP - BRU
2 stops16h 51mAmerican Airlines
Deal found 9/16$7,211
This KLM deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1710:45 amBRU - ECP
1 stop15h 45mKLM
Thu 9/259:13 amECP - BRU
1 stop16h 27mKLM
Deal found 9/14$7,425

Cheapflights Fare Finder

 
Customize your flight search to find flights from Bruxelles-National to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Brussels Bruxelles-National Airport to Panama City that are best for you.

Fly from

Bruxelles-National

Fly to

Panama City

Route

Depart

Return

Price

BrusselsPanama City

BRU - ECP

BRUECP

Brussels Bruxelles-National

Thu 1/15

5:30 pm-8:31 pm

2 stops34h 01m

Panama City NW Florida Beaches

Wed 3/4

4:59 pm-4:20 pm

2 stops16h 21m

$621

BrusselsPanama City

BRU - ECP

BRUECP

Brussels Bruxelles-National

Thu 1/15

5:30 pm-8:31 pm

2 stops34h 01m

Panama City NW Florida Beaches

Sun 3/1

6:55 am-10:50 am

2 stops20h 55m

$621

BrusselsPanama City

BRU - ECP

BRUECP

Brussels Bruxelles-National

Sat 1/17

9:55 am-8:31 pm

2 stops17h 36m

Panama City NW Florida Beaches

Tue 3/3

2:57 pm-1:35 pm

2 stops15h 38m

$621

BrusselsPanama City

BRU - ECP

BRUECP

Brussels Bruxelles-National

Fri 1/16

9:50 am-8:31 pm

2 stops17h 41m

Panama City NW Florida Beaches

Tue 3/3

4:59 pm-1:35 pm

2 stops13h 36m

$621

BrusselsPanama City

BRU - ECP

BRUECP

Brussels Bruxelles-National

Mon 1/12

5:30 pm-8:31 pm

2 stops34h 01m

Panama City NW Florida Beaches

Sun 3/1

3:45 pm-7:55 pm

2 stops21h 10m

$621

BrusselsPanama City

BRU - ECP

BRUECP

Brussels Bruxelles-National

Tue 1/13

12:00 pm-8:31 pm

2 stops39h 31m

Panama City NW Florida Beaches

Thu 3/5

2:57 pm-2:05 pm

2 stops16h 08m

$621

BrusselsPanama City

BRU - ECP

BRUECP

Brussels Bruxelles-National

Sat 1/17

9:55 am-8:31 pm

2 stops17h 36m

Panama City NW Florida Beaches

Wed 3/4

2:57 pm-10:50 am

2 stops36h 53m

$621

BrusselsPanama City

BRU - ECP

BRUECP

Brussels Bruxelles-National

Thu 10/30

5:30 pm-6:15 pm

2 stops30h 45m

Panama City NW Florida Beaches

Thu 11/6

2:37 pm-5:00 pm

2 stops19h 23m

$621

BrusselsPanama City

BRU - ECP

BRUECP

Brussels Bruxelles-National

Sat 1/17

9:55 am-8:31 pm

2 stops17h 36m

Panama City NW Florida Beaches

Sat 2/28

2:57 pm-8:50 pm

2 stops22h 53m

$621

BrusselsPanama City

BRU - ECP

BRUECP

Brussels Bruxelles-National

Fri 1/16

9:50 am-8:31 pm

2 stops17h 41m

Panama City NW Florida Beaches

Sat 2/28

11:17 am-4:35 pm

2 stops22h 18m

$621

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 12 results
1
2

Best time to book a flight from Bruxelles-National to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Bruxelles-National with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 16, 2025.
Read through reviews of airlines operating flights from Brussels Bruxelles-National Airport to Panama City, such as KLM. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.8
Good
1,386 reviews

Boarding

7.8

Overall

7.8

Crew

8.4

Entertainment

7.2

Food

7.3

Comfort

7.7

Reviews

1 / 20
4.0
Okay

Mark,Sep 2025

AMS - BHX

Crew and snacks were good, boarding wasn't great as busses were used rather than boarding tunnels. Also endured a one hour delay.
KLM
7.8
Good
1,386 reviews
KLM
7.8
Good
1,386 reviews

Boarding

7.8

Overall

7.8

Crew

8.4

Entertainment

7.2

Food

7.3

Comfort

7.7

Reviews

1 / 20
4.0
Okay

Mark,Sep 2025

AMS - BHX

Crew and snacks were good, boarding wasn't great as busses were used rather than boarding tunnels. Also endured a one hour delay.

Related info for your journey

Find useful and relevant information for your journey from Bruxelles-National to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Brussels Bruxelles-National?

    Most people fly into Panama City NW Florida Beaches (ECP) if they book a flight to Panama City from Brussels Bruxelles-National. On average, NW Florida Beaches has 0 inbound flights from Brussels Bruxelles-National per day from 1 airline. Panama City NW Florida Beaches is conveniently located just 16.0 mi from Panama City’s city center.

  • How long is the flight from Brussels Bruxelles-National Airport to Panama City, Florida?

    For as low as $621, American Airlines can have you in Panama City, Florida from Brussels Bruxelles-National Airport in 34h 01m. Airlines will cover a distance of 4631 mi.

  • What is the cheapest airline to fly from Brussels Bruxelles-National Airport to Panama City, Florida round-trip?

    Our cheapest airline available from Brussels Bruxelles-National Airport to Panama City, Florida is KLM. Our recent data shows that you can find tickets from as low as $603 on this airline.

  • Can I find deals for flights from Bruxelles-National to Panama City that include hotel bookings?

    Yes. In addition to deals on Bruxelles-National to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Bruxelles-National to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Bruxelles-National to Panama City.

  • Can I find deals for business class flights from Bruxelles-National to Panama City?

    Yes. Cheapflights offers flight deals from Bruxelles-National to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Brussels Bruxelles-National Airport to Panama City, Florida?

    Currently, January is the cheapest month in which you can book a flight from Brussels Bruxelles-National Airport to Panama City, Florida (average of $346). Flying from Brussels Bruxelles-National Airport to Panama City, Florida in March is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from Bruxelles-National to Panama City

Discover the top airline that operate flights from Bruxelles-National to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
KLMCheapest$603Average$609FlexibilityNo cancel feeOn-time75%

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