HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama City

$657+ Cheap flights from Bruxelles-National (BRU) to Panama City, FL (ECP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/1. Fares are subject to change and may not be available on all flights or dates of travel.
BRU — ECP
Dec 20 — Dec 271
Sat 12/20
Sat 12/27
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Bruxelles-National to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Bruxelles-National to Panama City

Best flights from Bruxelles-National to Panama City
Discover carefully curated flight deals from Bruxelles-National to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 20, 2025.

This United Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/18:30 amBRU - ECP
2 stops20h 26mUnited Airlines
Thu 4/166:40 amECP - BRU
2 stops30h 20mUnited Airlines
Deal found 11/20$657
This American Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1910:15 amBRU - ECP
2 stops29h 45mAmerican Airlines
Mon 3/2311:18 amECP - BRU
2 stops17h 52mAmerican Airlines
Deal found 11/18$664
This United Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/29:30 amBRU - ECP
2 stops31h 22mUnited Airlines
Thu 4/164:55 pmECP - BRU
2 stops20h 05mUnited Airlines
Deal found 11/20$657
This United Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/18:30 amBRU - ECP
2 stops20h 26mUnited Airlines
Tue 4/1411:15 amECP - BRU
2 stops19h 00mUnited Airlines
Deal found 11/20$657
This United Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/18:30 amBRU - ECP
2 stops20h 26mUnited Airlines
Wed 4/152:15 pmECP - BRU
2 stops22h 45mUnited Airlines
Deal found 11/20$657
This United Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/18:30 amBRU - ECP
2 stops20h 26mUnited Airlines
Sun 4/126:40 amECP - BRU
2 stops23h 35mUnited Airlines
Deal found 11/20$657
This United Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/210:30 amBRU - ECP
2 stops30h 22mUnited Airlines
Mon 4/1311:15 amECP - BRU
2 stops19h 00mUnited Airlines
Deal found 11/20$657
This United Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3110:30 amBRU - ECP
2 stops33h 39mUnited Airlines
Tue 4/144:55 pmECP - BRU
2 stops20h 05mUnited Airlines
Deal found 11/20$657
This United Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/210:30 amBRU - ECP
2 stops30h 22mUnited Airlines
Fri 4/1711:15 amECP - BRU
2 stops38h 45mUnited Airlines
Deal found 11/20$658
This United Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/319:30 amBRU - ECP
2 stops31h 22mUnited Airlines
Sat 4/114:55 pmECP - BRU
2 stops31h 20mUnited Airlines
Deal found 11/20$658
This United Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/19:30 amBRU - ECP
2 stops19h 26mUnited Airlines
Sat 4/114:55 pmECP - BRU
2 stops33h 05mUnited Airlines
Deal found 11/20$658

Cheap flight deals from Bruxelles-National to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Bruxelles-National (BRU) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
1 star

Round-trip from

$657
(United Airlines)
Provider with most accurate pricing for Brussels Bruxelles-National-Panama City NW Florida Beaches flight deals.
Search Deals
Provider most trusted by Cheapflights users for Brussels Bruxelles-National-Panama City NW Florida Beaches flights.
Search Deals
From Brussels Bruxelles-National to Panama City NW Florida Beaches
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Bruxelles-National to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
Use the filters below to find and compare flights from Brussels Bruxelles-National Airport to Panama City that are best for you.

Fly from

Bruxelles-National

Fly to

Panama City

Route

Depart

Return

Price

BrusselsPanama City

BRU - ECP

BRUECP

Brussels Bruxelles-National

Wed 4/1

8:30 am-9:56 pm

2 stops20h 26m

Panama City NW Florida Beaches

Thu 4/16

6:40 am-8:00 pm

2 stops30h 20m

$657

BrusselsPanama City

BRU - ECP

BRUECP

Brussels Bruxelles-National

Thu 4/2

9:30 am-9:52 am

2 stops31h 22m

Panama City NW Florida Beaches

Thu 4/16

4:55 pm-8:00 pm

2 stops20h 05m

$657

BrusselsPanama City

BRU - ECP

BRUECP

Brussels Bruxelles-National

Wed 4/1

8:30 am-9:56 pm

2 stops20h 26m

Panama City NW Florida Beaches

Tue 4/14

11:15 am-1:15 pm

2 stops19h 00m

$657

BrusselsPanama City

BRU - ECP

BRUECP

Brussels Bruxelles-National

Wed 4/1

8:30 am-9:56 pm

2 stops20h 26m

Panama City NW Florida Beaches

Wed 4/15

2:15 pm-8:00 pm

2 stops22h 45m

$657

BrusselsPanama City

BRU - ECP

BRUECP

Brussels Bruxelles-National

Wed 4/1

8:30 am-9:56 pm

2 stops20h 26m

Panama City NW Florida Beaches

Sun 4/12

6:40 am-1:15 pm

2 stops23h 35m

$657

BrusselsPanama City

BRU - ECP

BRUECP

Brussels Bruxelles-National

Thu 4/2

10:30 am-9:52 am

2 stops30h 22m

Panama City NW Florida Beaches

Mon 4/13

11:15 am-1:15 pm

2 stops19h 00m

$657

BrusselsPanama City

BRU - ECP

BRUECP

Brussels Bruxelles-National

Tue 3/31

10:30 am-1:09 pm

2 stops33h 39m

Panama City NW Florida Beaches

Tue 4/14

4:55 pm-8:00 pm

2 stops20h 05m

$657

BrusselsPanama City

BRU - ECP

BRUECP

Brussels Bruxelles-National

Thu 4/2

10:30 am-9:52 am

2 stops30h 22m

Panama City NW Florida Beaches

Fri 4/17

11:15 am-9:00 am

2 stops38h 45m

$658

BrusselsPanama City

BRU - ECP

BRUECP

Brussels Bruxelles-National

Tue 3/31

9:30 am-9:52 am

2 stops31h 22m

Panama City NW Florida Beaches

Sat 4/11

4:55 pm-7:15 am

2 stops31h 20m

$658

BrusselsPanama City

BRU - ECP

BRUECP

Brussels Bruxelles-National

Wed 4/1

9:30 am-9:56 pm

2 stops19h 26m

Panama City NW Florida Beaches

Sat 4/11

4:55 pm-9:00 am

2 stops33h 05m

$658

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/20

Showing 1-10 of 11 results
1
2
  • Most accurate provider: When it comes to deals on Brussels Bruxelles-National Airport-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Brussels Bruxelles-National Airport-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Brussels Bruxelles-National Airport-Panama City, Florida flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Brussels Bruxelles-National Airport-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Brussels Bruxelles-National Airport-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Bruxelles-National to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Bruxelles-National with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Bruxelles-National to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Brussels Bruxelles-National?

    Most people fly into Panama City NW Florida Beaches (ECP) if they book a flight to Panama City from Brussels Bruxelles-National. On average, NW Florida Beaches has 0 inbound flights from Brussels Bruxelles-National per day from 0 airlines. Panama City NW Florida Beaches is conveniently located just 16.0 mi from Panama City’s city center.

  • How long is the flight from Brussels Bruxelles-National Airport to Panama City, Florida?

    For as low as $657, United Airlines can have you in Panama City, Florida from Brussels Bruxelles-National Airport in 20h 26m. Airlines will cover a distance of 4631 mi.

  • Can I find deals for flights from Bruxelles-National to Panama City that include hotel bookings?

    Yes. In addition to deals on Bruxelles-National to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Bruxelles-National to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Bruxelles-National to Panama City.

  • Can I find deals for business class flights from Bruxelles-National to Panama City?

    Yes. Cheapflights offers flight deals from Bruxelles-National to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.