HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama City

$418+ Cheap flights from Myrtle Beach to Panama City, FL (MYR - ECP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/5. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — ECP
Mar 1 — Mar 81
Sun 3/1
Sun 3/8
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Myrtle Beach to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Myrtle Beach to Panama City

Cheapest flights from Myrtle Beach to Panama City
Explore the most affordable flight options available from Myrtle Beach to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 30, 2026.

This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/510:35 am
MYR
-
ECP
2 stops11h 45m
Southwest
Sun 3/86:40 am
ECP
-
MYR
1 stop5h 50m
Southwest
Deal found 1/27$418
This American Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/218:34 pm
MYR
-
ECP
1 stop4h 07m
American Airlines
Sat 6/272:28 pm
ECP
-
MYR
1 stop6h 15m
American Airlines
Deal found 1/29$483
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/106:23 am
MYR
-
ECP
1 stop6h 10m
American Airlines
Sun 2/157:19 am
ECP
-
MYR
1 stop6h 08m
American Airlines
Deal found 1/28$504
This Southwest deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/108:15 am
MYR
-
ECP
2 stops10h 55m
Southwest
Sun 2/157:35 am
ECP
-
MYR
1 stop4h 00m
Southwest
Deal found 1/28$598
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/18:00 am
MYR
-
ECP
1 stop4h 33m
American Airlines
Tue 2/312:03 pm
ECP
-
MYR
1 stop3h 56m
American Airlines
Deal found 1/28$717
This Southwest deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/18:20 am
MYR
-
ECP
2 stops11h 25m
Southwest
Tue 2/38:00 am
ECP
-
MYR
1 stop8h 00m
Southwest
Deal found 1/28$728
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/145:13 pm
MYR
-
ECP
2 stops23h 58m
United Airlines
Wed 2/186:30 am
ECP
-
MYR
2 stops33h 19m
United Airlines
Deal found 1/28$985

Find flight deals from Myrtle Beach to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 30, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$418
(Southwest)

Popular in

March

Cheapest in

September

Average price

$360
Provider with most accurate pricing for Myrtle Beach Intl-Panama City NW Florida Beaches flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Panama City NW Florida Beaches flights.
Search Deals
From Myrtle Beach Intl to Panama City NW Florida Beaches
Search Deals
Highest demand for flights based on searches. 29% potential increase in price ($141 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($22 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 30, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Panama City that are best for you.

Fly from

Myrtle Beach

Fly to

Panama City

Route

Depart

Return

Price

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Thu 3/5

10:35 am-9:20 pm

2 stops11h 45m

Panama City NW Florida Beaches

Sun 3/8

6:40 am-1:30 pm

1 stop5h 50m

$418

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Sun 6/21

6:07 pm-11:41 pm

1 stop6h 34m

Panama City NW Florida Beaches

Sat 6/27

2:28 pm-7:54 pm

1 stop4h 26m

$483

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Tue 2/10

6:23 am-11:33 am

1 stop6h 10m

Panama City NW Florida Beaches

Sun 2/15

7:19 am-2:27 pm

1 stop6h 08m

$504

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Tue 2/10

8:15 am-6:10 pm

2 stops10h 55m

Panama City NW Florida Beaches

Sun 2/15

7:35 am-12:35 pm

1 stop4h 00m

$598

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Sat 2/14

5:13 pm-9:56 pm

2 stops29h 43m

Panama City NW Florida Beaches

Wed 2/18

5:00 pm-4:49 pm

2 stops22h 49m

$985

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Compare providers for flights from Myrtle Beach to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Panama City in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Myrtle Beach-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Panama City, Florida flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Myrtle Beach-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Myrtle Beach to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Panama City

What is the cheapest month to book a flight from Myrtle Beach to Panama City, Florida?

Currently, March is the cheapest month in which you can book a flight from Myrtle Beach to Panama City, Florida (average of $134). Flying from Myrtle Beach to Panama City, Florida in January is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated January 30, 2026.
Get a feel of what it's like to fly with Delta from Myrtle Beach to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,126 reviews

Crew

8.5

Food

7.2

Boarding

8.1

Comfort

7.9

Overall

7.9

Entertainment

7.8

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
8,126 reviews
Delta
7.9
Good
8,126 reviews

Crew

8.5

Food

7.2

Boarding

8.1

Comfort

7.9

Overall

7.9

Entertainment

7.8

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Myrtle Beach to Panama City, Florida?

    A quick flight from Myrtle Beach to Panama City, Florida can take about 6h 34m. Southwest provides one of the quickest options available for as low as $483. Myrtle Beach and Panama City, Florida are separated by a distance of 463 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Myrtle Beach to Panama City, Florida round-trip?

    Delta, at $207, was found to be the cheapest airline from Myrtle Beach to Panama City, Florida.. Delta is priced at 39% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Myrtle Beach to Panama City that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Panama City.

  • Can I find deals for business class flights from Myrtle Beach to Panama City?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Panama City, Florida?

    Currently, March is the cheapest month in which you can book a flight from Myrtle Beach to Panama City, Florida (average of $134). Flying from Myrtle Beach to Panama City, Florida in January is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Myrtle Beach to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to Fort Lauderdale flights
Charlotte to Miami flights
Charlotte to Orlando flights
Charlotte to Tampa flights
Charleston to Fort Lauderdale flights
Charlotte to West Palm Beach flights
Charleston to Miami flights
Charlotte to Fort Myers flights
Charlotte to Key West flights
Charlotte to Jacksonville flights
Charlotte to Sarasota flights
Myrtle Beach to Orlando flights
Myrtle Beach to Fort Lauderdale flights
Savannah to Miami flights
Greenville to Miami flights
Charleston to Tampa flights
Charleston to Orlando flights
Myrtle Beach to Tampa flights
Columbia to Fort Lauderdale flights
Columbia to Miami flights
Columbia to Orlando flights
Charlotte to Panama City flights
Greenville to Fort Lauderdale flights
Columbia to Tampa flights
Charlotte to Pensacola flights
Charleston to Key West flights
Myrtle Beach to Miami flights
Greenville to Orlando flights
Greenville to Tampa flights
Charleston to Fort Myers flights
Savannah to Orlando flights
Charleston to Sarasota flights
Columbia to Fort Myers flights
Savannah to Tampa flights
Columbia to Key West flights
Charlotte to Melbourne flights
Augusta to Miami flights
Columbia to West Palm Beach flights
Greenville to Pensacola flights
Myrtle Beach to West Palm Beach flights
Myrtle Beach to Sarasota flights
Charlotte to Gainesville flights
Myrtle Beach to Fort Myers flights
Greenville to Key West flights
Charleston to Pensacola flights
Savannah to Fort Lauderdale flights
Charleston to West Palm Beach flights
Savannah to Pensacola flights
Greenville to West Palm Beach flights
Greenville to Sarasota flights

Top airline flying from Myrtle Beach to Panama City

Discover the top airline that operate flights from Myrtle Beach to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 30, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$207Average$301FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.