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$274+ Cheap flights from Myrtle Beach to Panama City, FL (MYR - ECP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/4. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — ECP
Jan 14 — Jan 211
Wed 1/14
Wed 1/21
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Panama City

Best flights from Myrtle Beach to Panama City
Discover carefully curated flight deals from Myrtle Beach to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 15, 2025.

This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/48:00 amMYR - ECP
1 stop4h 33mAmerican Airlines
Sat 2/214:30 pmECP - MYR
1 stop6h 26mAmerican Airlines
Deal found 12/13$274
This Southwest deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/48:15 amMYR - ECP
2 stops10h 55mSouthwest
Sat 2/217:40 amECP - MYR
1 stop4h 00mSouthwest
Deal found 12/13$283
This Delta deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/126:00 amMYR - ECP
1 stop4h 09mDelta
Mon 1/197:20 amECP - MYR
1 stop5h 10mDelta
Deal found 12/15$315
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/126:25 pmMYR - ECP
2 stops18h 08mAmerican Airlines
Mon 1/191:34 pmECP - MYR
1 stop24h 21mAmerican Airlines
Deal found 12/15$630

Find flight deals from Myrtle Beach to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 15, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$274
(American Airlines)

Popular in

March

Cheapest in

September

Average price

$276
Provider with most accurate pricing for Myrtle Beach Intl-Panama City NW Florida Beaches flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Panama City NW Florida Beaches flights.
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From Myrtle Beach Intl to Panama City NW Florida Beaches
Search Deals
Highest demand for flights based on searches. 29% potential increase in price ($143 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($21 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Panama City that are best for you.

Fly from

Myrtle Beach

Fly to

Panama City

Route

Depart

Return

Price

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Wed 2/4

8:00 am-11:33 am

1 stop4h 33m

Panama City NW Florida Beaches

Sat 2/21

4:30 pm-11:56 pm

1 stop6h 26m

$274

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Wed 2/4

8:15 am-6:10 pm

2 stops10h 55m

Panama City NW Florida Beaches

Sat 2/21

7:40 am-12:40 pm

1 stop4h 00m

$283

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Mon 1/12

6:00 am-9:09 am

1 stop4h 09m

Panama City NW Florida Beaches

Mon 1/19

7:20 am-1:30 pm

1 stop5h 10m

$315

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Mon 1/12

6:25 pm-11:33 am

2 stops18h 08m

Panama City NW Florida Beaches

Mon 1/19

1:34 pm-2:55 pm

1 stop24h 21m

$630

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/13

Compare providers for flights from Myrtle Beach to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Panama City in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Myrtle Beach-Panama City, Florida flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Myrtle Beach-Panama City, Florida flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Panama City, Florida flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Myrtle Beach-Panama City, Florida flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Myrtle Beach to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Panama City

What is the cheapest month to book a flight from Myrtle Beach to Panama City, Florida?

Currently, September is the cheapest month in which you can book a flight from Myrtle Beach to Panama City, Florida (average of $138). Flying from Myrtle Beach to Panama City, Florida in January is currently the most expensive (average of $278). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to ECP?

Find hourly flight availability from Myrtle Beach to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 15, 2025.

When flying from Myrtle Beach to Panama City, Florida, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 58% versus a flight at noon.

How much does it cost to fly round-trip from Myrtle Beach to Panama City, Florida?

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated December 15, 2025.
Get a feel of what it's like to fly with Delta from Myrtle Beach to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,008 reviews

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

7.9

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
8,008 reviews
Delta
7.9
Good
8,008 reviews

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

7.9

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Myrtle Beach to Panama City, Florida?

    A quick flight from Myrtle Beach to Panama City, Florida can take about 4h 33m. American Airlines provides one of the quickest options available for as low as $274. Myrtle Beach and Panama City, Florida are separated by a distance of 463 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Myrtle Beach to Panama City, Florida round-trip?

    Delta, at $207, was found to be the cheapest airline from Myrtle Beach to Panama City, Florida.. Delta is priced at 39% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Myrtle Beach to Panama City that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Panama City.

  • Can I find deals for business class flights from Myrtle Beach to Panama City?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Panama City, Florida?

    Currently, September is the cheapest month in which you can book a flight from Myrtle Beach to Panama City, Florida (average of $138). Flying from Myrtle Beach to Panama City, Florida in January is currently the most expensive (average of $278). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

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Top airline flying from Myrtle Beach to Panama City

Discover the top airline that operate flights from Myrtle Beach to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$207Average$304FlexibilityNo cancel feeOn-timeN/A

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