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Panama City

$210+ Cheap flights from Myrtle Beach to Panama City, FL (MYR - ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/5. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — ECP
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2025.

Round-trip from

$247
(American Airlines)

One-way from

$210
(American Airlines)

Popular in

March

Cheapest in

September

Average price

$207
From Myrtle Beach Intl to Panama City NW Florida Beaches
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One-way flight from Myrtle Beach Intl to Panama City NW Florida Beaches
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Highest demand for flights based on searches. 29% potential increase in price ($141 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($21 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Myrtle Beach to Panama City

Cheapest flights from Myrtle Beach to Panama City
Explore the most affordable flight options available from Myrtle Beach to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/57:30 amMYR - ECP
1 stop4h 59mAmerican Airlines
Mon 11/105:55 pmECP - MYR
1 stop3h 41mAmerican Airlines
Deal found 9/13$247
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/236:58 pmMYR - ECP
1 stop5h 12mDelta
Tue 10/285:00 pmECP - MYR
1 stop5h 57mDelta
Deal found 9/13$302
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/58:00 amMYR - ECP
2 stops12h 05mSouthwest
Mon 11/107:30 amECP - MYR
1 stop3h 35mSouthwest
Deal found 9/13$378
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/235:50 pmMYR - ECP
1 stop5h 45mSouthwest
Tue 10/289:50 amECP - MYR
2 stops8h 55mSouthwest
Deal found 9/13$394
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/296:00 amMYR - ECP
1 stop3h 08mDelta
Fri 10/36:00 amECP - MYR
1 stop3h 10mDelta
Deal found 9/14$407
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2610:35 amMYR - ECP
1 stop6h 00mSouthwest
Sat 9/278:05 amECP - MYR
1 stop3h 50mSouthwest
Deal found 9/14$527

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Panama City that are best for you.

Fly from

Myrtle Beach

Fly to

Panama City

Route

Depart

Return

Price

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Wed 11/5

7:30 am-11:29 am

1 stop4h 59m

Panama City NW Florida Beaches

Mon 11/10

5:55 pm-10:36 pm

1 stop3h 41m

$247

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Thu 10/23

6:58 pm-11:10 pm

1 stop5h 12m

Panama City NW Florida Beaches

Tue 10/28

5:00 pm-11:57 pm

1 stop5h 57m

$302

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Wed 11/5

8:00 am-7:05 pm

2 stops12h 05m

Panama City NW Florida Beaches

Mon 11/10

7:30 am-12:05 pm

1 stop3h 35m

$378

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Thu 10/23

5:50 pm-10:35 pm

1 stop5h 45m

Panama City NW Florida Beaches

Tue 10/28

9:50 am-7:45 pm

2 stops8h 55m

$394

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Mon 9/29

6:00 am-8:08 am

1 stop3h 08m

Panama City NW Florida Beaches

Fri 10/3

6:00 am-10:10 am

1 stop3h 10m

$407

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Fri 9/26

10:35 am-3:35 pm

1 stop6h 00m

Panama City NW Florida Beaches

Sat 9/27

8:05 am-12:55 pm

1 stop3h 50m

$527

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Wed 11/5

7:41 pm-11:15 pm

1 stop4h 34m

$210

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/12

Best time to book a flight from Myrtle Beach to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Panama City

What is the cheapest month to book a flight from Myrtle Beach to Panama City, Florida?

Currently, January is the cheapest month in which you can book a flight from Myrtle Beach to Panama City, Florida (average of $346). Flying from Myrtle Beach to Panama City, Florida in March is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to ECP?

Find hourly flight availability from Myrtle Beach to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

When flying from Myrtle Beach to Panama City, Florida, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 48% versus a flight at noon.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 15, 2025.
Get a feel of what it's like to fly with Delta from Myrtle Beach to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,956 reviews

Overall

8.0

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

CAE - ATL

On time flights; courteous staff; efficient boarding system! Thank you!
Delta
8.0
Very good
7,956 reviews
Delta
8.0
Very good
7,956 reviews

Overall

8.0

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

CAE - ATL

On time flights; courteous staff; efficient boarding system! Thank you!

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Myrtle Beach to Panama City, Florida?

    A quick flight from Myrtle Beach to Panama City, Florida can take about 4h 59m. American Airlines provides one of the quickest options available for as low as $247. Myrtle Beach and Panama City, Florida are separated by a distance of 463 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Myrtle Beach to Panama City, Florida round-trip?

    Delta, at $207, was found to be the cheapest airline from Myrtle Beach to Panama City, Florida.. Delta is priced at 39% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Myrtle Beach to Panama City that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Panama City.

  • Can I find deals for business class flights from Myrtle Beach to Panama City?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Panama City, Florida?

    Currently, January is the cheapest month in which you can book a flight from Myrtle Beach to Panama City, Florida (average of $346). Flying from Myrtle Beach to Panama City, Florida in March is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

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Mexico Beach

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Alternative routes for Myrtle Beach to Panama City

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Top airline flying from Myrtle Beach to Panama City

Discover the top airline that operate flights from Myrtle Beach to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$207Average$301FlexibilityNo cancel feeOn-timeN/A

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