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Panama City

$111+ Cheap flights from Missouri to Panama City, FL (ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/2. Fares are subject to change and may not be available on all flights or dates of travel.
STL — ECP
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
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Cheap flight deals from Missouri to Panama City

Keep the following information in mind while searching for Missouri to Panama City flight deals. Data was last updated May 1, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$221
(Delta)

One-way from

$111
(Delta)

Popular in

December

Cheapest in

January

Average price

$418

Good round-trip deal

$390 or less

Good one-way deal

$332 or less
Provider with most accurate pricing for Kansas City-Panama City NW Florida Beaches flight deals.
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Provider most trusted by Cheapflights users for Kansas City-Panama City NW Florida Beaches flights.
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From Missouri to Panama City NW Florida Beaches
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One-way flight from Missouri to Panama City NW Florida Beaches
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Highest demand for flights based on searches. 4% potential increase in price ($18 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
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Average for round-trip flights in May 2025
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Price to beat on a round-trip flight from Missouri to Panama City NW Florida Beaches.
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Price to beat on a one-way flight from Missouri to Panama City NW Florida Beaches.
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Find flight deals from Missouri to Panama City

Cheapest flights from Missouri to Panama City
Explore the most affordable flight options available from Missouri to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/275:12 amSTL - ECP
1 stop4h 36mAmerican Airlines
Tue 6/32:29 pmECP - STL
1 stop4h 54mAmerican Airlines
Deal found 4/29$199
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/266:00 amSTL - ECP
1 stop3h 49mDelta
Fri 5/306:00 amECP - STL
1 stop6h 04mDelta
Deal found 4/30$221
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/295:26 pmMCI - ECP
1 stop5h 38mDelta
Mon 6/26:00 amECP - MCI
1 stop5h 07mDelta
Deal found 4/30$227
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/55:00 amSGF - ECP
1 stop5h 47mAmerican Airlines
Wed 7/93:52 pmECP - SGF
1 stop6h 20mAmerican Airlines
Deal found 4/30$249
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/276:50 pmSTL - ECP
Nonstop1h 45mSouthwest
Tue 6/37:50 amECP - STL
Nonstop1h 50mSouthwest
Deal found 4/29$277
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/296:56 pmSGF - ECP
1 stop4h 08mDelta
Wed 6/47:15 amECP - SGF
1 stop4h 05mDelta
Deal found 4/29$289
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/216:00 amMCI - ECP
2 stops7h 49mAmerican Airlines
Sun 5/253:35 pmECP - MCI
1 stop7h 17mAmerican Airlines
Deal found 4/30$302
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/308:35 amSGF - ECP
1 stop7h 45mUnited Airlines
Wed 6/45:07 pmECP - SGF
1 stop4h 53mUnited Airlines
Deal found 4/29$319
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/166:33 amSTL - ECP
2 stops9h 48mUnited Airlines
Sat 8/236:30 amECP - STL
2 stops8h 02mUnited Airlines
Deal found 4/28$333
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/55:00 pmMCI - ECP
Nonstop2h 10mSouthwest
Fri 6/136:10 pmECP - MCI
1 stop6h 00mSouthwest
Deal found 4/29$360
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/36:00 amMCI - ECP
2 stops10h 20mUnited Airlines
Sat 6/146:30 amECP - MCI
1 stop5h 39mUnited Airlines
Deal found 4/29$390

Cheapflights Fare Finder

Customize your flight search to find flights from Missouri to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from Missouri to Panama City that are best for you.

Fly from

Missouri

Fly to

Panama City

Route

Depart

Return

Price

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Mon 5/26

6:00 am-9:49 am

1 stop3h 49m

Panama City NW Florida Beaches

Fri 5/30

6:00 am-12:04 pm

1 stop6h 04m

$221

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Mon 5/26

7:10 am-1:49 pm

1 stop6h 39m

Panama City NW Florida Beaches

Fri 5/30

2:29 pm-11:51 pm

2 stops9h 22m

$226

Kansas CityPanama City

MCI - ECP

MCIECP

Kansas City

Thu 5/29

5:26 pm-11:04 pm

1 stop5h 38m

Panama City NW Florida Beaches

Mon 6/2

6:00 am-11:07 am

1 stop5h 07m

$227

SpringfieldPanama City

SGF - ECP

SGFECP

Springfield-Branson

Sat 7/5

5:00 am-10:47 am

1 stop5h 47m

Panama City NW Florida Beaches

Wed 7/9

3:52 pm-10:12 pm

1 stop6h 20m

$249

SpringfieldPanama City

SGF - ECP

SGFECP

Springfield-Branson

Thu 5/29

6:56 pm-11:04 pm

1 stop4h 08m

Panama City NW Florida Beaches

Sun 6/8

6:00 am-10:44 am

1 stop4h 44m

$289

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Wed 5/28

6:50 pm-8:35 pm

Nonstop1h 45m

Panama City NW Florida Beaches

Wed 6/4

7:50 am-9:40 am

Nonstop1h 50m

$294

Kansas CityPanama City

MCI - ECP

MCIECP

Kansas City

Wed 5/21

6:00 am-1:49 pm

2 stops7h 49m

Panama City NW Florida Beaches

Sun 5/25

3:35 pm-10:52 pm

1 stop7h 17m

$302

SpringfieldPanama City

SGF - ECP

SGFECP

Springfield-Branson

Fri 5/30

8:35 am-4:20 pm

1 stop7h 45m

Panama City NW Florida Beaches

Wed 6/4

5:07 pm-10:00 pm

1 stop4h 53m

$319

Kansas CityPanama City

MCI - ECP

MCIECP

Kansas City

Thu 6/5

5:00 pm-7:10 pm

Nonstop2h 10m

Panama City NW Florida Beaches

Fri 6/13

6:10 pm-12:10 am

1 stop6h 00m

$360

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Wed 5/28

8:10 am-4:20 pm

2 stops8h 10m

Panama City NW Florida Beaches

Wed 6/4

6:30 am-9:25 pm

3 stops14h 55m

$372

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/30

Showing 1-10 of 21 results
1
2
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Best time to book a flight from Missouri to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Panama City

What is the cheapest month to book a flight from Missouri to Panama City, Florida?

Currently, January is the cheapest month in which you can book a flight from Missouri to Panama City, Florida (average of $346). Flying from Missouri to Panama City, Florida in March is currently the most expensive (average of $461). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to ECP?

Find hourly flight availability from Missouri to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

When flying from Missouri to Panama City, Florida, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Panama City by month

Plan your trip to Panama City by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama City, Florida ranges from 2.8 - 7.9 inches per month. July is typically the wettest month, when rainfall can reach 7.9 in. May is typically the driest time to visit Panama City, Florida when rainfall is around 2.8 in.

Temperature in Panama City by month

Plan your trip to Panama City by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama City, Florida, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 53.6 F).

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated May 1, 2025.
Read reviews from past customers who have flown Southwest, Delta and United Airlines from Missouri to Panama City. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,294 reviews

Boarding

8.2

Crew

8.6

Overall

8.0

Food

7.1

Entertainment

7.6

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Southwest
8.0
Very good
4,294 reviews
Southwest
8.0
Very good
4,294 reviews

Boarding

8.2

Crew

8.6

Overall

8.0

Food

7.1

Entertainment

7.6

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Delta
8.0
Very good
7,934 reviews
Southwest
8.0
Very good
4,294 reviews

Boarding

8.2

Crew

8.6

Overall

8.0

Food

7.1

Entertainment

7.6

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
United Airlines
7.4
Good
8,696 reviews
Southwest
8.0
Very good
4,294 reviews

Boarding

8.2

Crew

8.6

Overall

8.0

Food

7.1

Entertainment

7.6

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,294 reviews

Boarding

8.2

Crew

8.6

Overall

8.0

Food

7.1

Entertainment

7.6

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Related info for your journey

Find useful and relevant information for your journey from Missouri to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Missouri?

    For a flight from Missouri to Panama City, you will be flying into NW Florida Beaches. Panama City NW Florida Beaches (ECP) is just 16.0 mi from the center of the city.

  • How popular is this Missouri to Panama City, Florida flight route?

    The Missouri to Panama City NW Florida Beaches flight path was viewed by 3 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from Missouri to Panama City, Florida one-way?

    The cheapest airline one-way is Delta, with whom users have recently found tickets for as low as $111. However, be on the lookout for offers from American Airlines and Southwest, as they are both options that can get you from Missouri to Panama City, Florida for a low price.

  • What are the most popular routes from Missouri to Panama City, Florida?

    When deciding which route to take from Missouri to Panama City, Florida consider Lambert-St Louis - Panama City NW Florida Beaches, Kansas City - Panama City NW Florida Beaches or Springfield-Branson - Panama City NW Florida Beaches as they are the most popular.

  • What are the cheapest flights from Missouri to Panama City, Florida?

    Looking for the cheapest flight from Missouri to Panama City, Florida? While on average our users pay $441, our data indicates the cheapest price to be $239. The most popular route (Lambert-St Louis - Panama City NW Florida Beaches), is priced around $277.

  • Can I find deals for flights from Missouri to Panama City that include hotel bookings?

    Yes. In addition to deals on Missouri to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Panama City.

  • Can I find deals for business class flights from Missouri to Panama City?

    Yes. Cheapflights offers flight deals from Missouri to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Panama City, Florida?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Panama City, Florida (average of $346). Flying from Missouri to Panama City, Florida in March is currently the most expensive (average of $461). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Missouri?

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Alternative routes for Missouri to Panama City

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Top 5 airlines flying from Missouri to Panama City

Discover the top 5 airlines that operate flights from Missouri to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$182Average$415FlexibilityNo cancel feeOn-time71%
DeltaCheapest$186Average$384FlexibilityNo cancel feeOn-timeN/A
Allegiant AirCheapest$192Average$233FlexibilityNo cancel feeOn-time88%
United AirlinesCheapest$256Average$455FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$347Average$459FlexibilityNo cancel feeOn-time63%

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