HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama City

$341+ Cheap flights from Mexico City (MEX) to Panama City, FL (ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/31. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — ECP
Aug 3 — Aug 101
Sun 8/3
Sun 8/10
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Mexico City to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Mexico City to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Mexico City (MEX) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 29, 2025.

Round-trip from

$502
(Delta)

One-way from

$341
(American Airlines)

Popular in

January

Cheapest in

July

Average price

$492
From Mexico City Benito Juarez to Panama City NW Florida Beaches
Search Deals
One-way flight from Mexico City Benito Juarez to Panama City NW Florida Beaches
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($53 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2025
Search Deals

Find flight deals from Mexico City to Panama City

Cheapest flights from Mexico City to Panama City
Explore the most affordable flight options available from Mexico City to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/258:55 amMEX - ECP
2 stops9h 53mDelta
Wed 8/277:10 amECP - MEX
2 stops9h 40mDelta
Deal found 7/28$502
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/279:35 amMEX - ECP
1 stop5h 45mUnited Airlines
Sun 8/316:30 amECP - MEX
1 stop27h 05mUnited Airlines
Deal found 7/28$503
This Aeromexico deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/277:00 amMEX - ECP
2 stops11h 48mAeromexico
Sun 8/316:00 amECP - MEX
2 stops18h 55mAeromexico
Deal found 7/27$575
This WestJet deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure WestJet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2612:05 amMEX - ECP
2 stops18h 43mWestJet
Sun 8/316:00 amECP - MEX
2 stops33h 05mWestJet
Deal found 7/27$1,357

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico City to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
Use the filters below to find and compare flights from Mexico City to Panama City that are best for you.

Fly from

Mexico City

Fly to

Panama City

Route

Depart

Return

Price

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Mon 8/25

8:55 am-7:48 pm

2 stops9h 53m

Panama City NW Florida Beaches

Wed 8/27

7:10 am-3:50 pm

2 stops9h 40m

$502

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Wed 8/27

9:35 am-4:20 pm

1 stop5h 45m

Panama City NW Florida Beaches

Sun 8/31

6:30 am-8:35 am

1 stop27h 05m

$503

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Wed 8/27

7:00 am-7:48 pm

2 stops11h 48m

Panama City NW Florida Beaches

Sun 8/31

6:00 am-11:55 pm

2 stops18h 55m

$575

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Tue 8/26

12:05 am-7:48 pm

2 stops18h 43m

Panama City NW Florida Beaches

Sun 8/31

6:00 am-2:05 pm

2 stops33h 05m

$1,357

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Fri 10/31

2:00 pm-10:58 am

1 stop19h 58m

$341

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Thu 10/30

1:10 am-10:43 pm

2 stops20h 33m

$1,665

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Best time to book a flight from Mexico City to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Mexico City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City to Panama City

What is the cheapest month to book a flight from Mexico City to Panama City, Florida?

Currently, January is the cheapest month in which you can book a flight from Mexico City to Panama City, Florida (average of $346). Flying from Mexico City to Panama City, Florida in March is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated July 29, 2025.
Get a feel of what it's like to fly with Delta, Aeromexico, and United Airlines from Mexico City to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,979 reviews

Food

7.3

Overall

8.0

Boarding

8.2

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Elizabeth,Sep 2023

MEX - ATL

Food was cheap and not healthful. Entertainment was poor choices. Flight was rocky but not pilots fault.
Delta
8.0
Very good
7,979 reviews
Delta
8.0
Very good
7,979 reviews

Food

7.3

Overall

8.0

Boarding

8.2

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Elizabeth,Sep 2023

MEX - ATL

Food was cheap and not healthful. Entertainment was poor choices. Flight was rocky but not pilots fault.
Aeromexico
7.5
Good
1,720 reviews
Delta
8.0
Very good
7,979 reviews

Food

7.3

Overall

8.0

Boarding

8.2

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Elizabeth,Sep 2023

MEX - ATL

Food was cheap and not healthful. Entertainment was poor choices. Flight was rocky but not pilots fault.
United Airlines
7.4
Good
8,896 reviews
Delta
8.0
Very good
7,979 reviews

Food

7.3

Overall

8.0

Boarding

8.2

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Elizabeth,Sep 2023

MEX - ATL

Food was cheap and not healthful. Entertainment was poor choices. Flight was rocky but not pilots fault.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,979 reviews

Food

7.3

Overall

8.0

Boarding

8.2

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Elizabeth,Sep 2023

MEX - ATL

Food was cheap and not healthful. Entertainment was poor choices. Flight was rocky but not pilots fault.
WestJet
7.2
Good
2,972 reviews
Delta
8.0
Very good
7,979 reviews

Food

7.3

Overall

8.0

Boarding

8.2

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Elizabeth,Sep 2023

MEX - ATL

Food was cheap and not healthful. Entertainment was poor choices. Flight was rocky but not pilots fault.

Related info for your journey

Find useful and relevant information for your journey from Mexico City to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Mexico City to Panama City, Florida round-trip?

    According to our current data, Delta ($502), United Airlines ($503), and Aeromexico ($575) offers the cheapest pricing from Mexico City to Panama City, Florida. Delta is currently priced 12% below the average price you’ll pay for this route.

  • Can I find deals for flights from Mexico City to Panama City that include hotel bookings?

    Yes. In addition to deals on Mexico City to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to Panama City.

  • Can I find deals for business class flights from Mexico City to Panama City?

    Yes. Cheapflights offers flight deals from Mexico City to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City to Panama City, Florida?

    Currently, January is the cheapest month in which you can book a flight from Mexico City to Panama City, Florida (average of $346). Flying from Mexico City to Panama City, Florida in March is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from Mexico City to Panama City

Discover the top airline that operate flights from Mexico City to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$468Average$578FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.