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Panama City

$336+ Cheap flights from Mexico City (MEX) to Panama City, FL (ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/8. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — ECP
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Mexico City to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Mexico City (MEX) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$500
(Delta)

One-way from

$336
(Delta)

Popular in

January

Cheapest in

July

Average price

$521
From Mexico City Benito Juarez to Panama City NW Florida Beaches
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One-way flight from Mexico City Benito Juarez to Panama City NW Florida Beaches
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Highest demand for flights based on searches. 10% potential increase in price ($65 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($20 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Mexico City to Panama City

Cheapest flights from Mexico City to Panama City
Explore the most affordable flight options available from Mexico City to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/303:50 pmMEX - ECP
1 stop6h 20mDelta
Mon 11/36:00 amECP - MEX
2 stops9h 30mDelta
Deal found 9/11$500
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/306:30 amMEX - ECP
1 stop8h 46mUnited Airlines
Tue 10/71:55 pmECP - MEX
2 stops10h 15mUnited Airlines
Deal found 9/9$502
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/24:40 pmMEX - ECP
1 stop28h 08mUnited Airlines
Tue 10/146:30 amECP - MEX
1 stop10h 10mUnited Airlines
Deal found 9/11$503
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/305:45 amMEX - ECP
2 stops16h 08mAmerican Airlines
Mon 11/35:55 pmECP - MEX
2 stops17h 35mAmerican Airlines
Deal found 9/9$514
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/21:55 pmMEX - ECP
2 stops20h 36mAmerican Airlines
Tue 10/146:49 amECP - MEX
2 stops14h 26mAmerican Airlines
Deal found 9/10$516
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/304:45 amMEX - ECP
1 stop10h 18mUnited Airlines
Mon 11/35:00 pmECP - MEX
1 stop17h 05mUnited Airlines
Deal found 9/9$517
This Trip.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/256:30 amMEX - ECP
1 stop6h 21mUnited Airlines
Sat 11/12:22 pmECP - MEX
1 stop22h 53mUnited Airlines
Deal found 9/10$536
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/259:35 amMEX - ECP
2 stops12h 06mDelta
Sat 11/19:29 amECP - MEX
2 stops10h 26mDelta
Deal found 9/10$542

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico City to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Mexico City to Panama City that are best for you.

Fly from

Mexico City

Fly to

Panama City

Route

Depart

Return

Price

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Thu 10/30

11:25 am-11:10 pm

1 stop10h 45m

Panama City NW Florida Beaches

Mon 11/3

6:00 am-3:30 pm

2 stops9h 30m

$500

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Wed 10/8

6:30 am-9:48 pm

1 stop14h 18m

Panama City NW Florida Beaches

Sun 10/12

6:30 am-8:35 am

1 stop27h 05m

$502

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Tue 9/30

4:40 am-9:48 pm

1 stop16h 08m

Panama City NW Florida Beaches

Tue 10/7

6:30 am-5:50 pm

1 stop12h 20m

$502

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Thu 10/2

11:35 am-4:16 pm

1 stop27h 41m

Panama City NW Florida Beaches

Tue 10/14

6:30 am-3:40 pm

1 stop10h 10m

$502

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Thu 10/2

7:25 am-5:56 pm

2 stops9h 31m

Panama City NW Florida Beaches

Tue 10/14

6:00 am-2:25 pm

2 stops9h 25m

$503

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Tue 9/30

7:01 am-7:30 pm

2 stops11h 29m

Panama City NW Florida Beaches

Tue 10/7

6:00 am-5:45 pm

2 stops12h 45m

$503

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Thu 10/30

5:45 am-10:53 pm

2 stops16h 08m

Panama City NW Florida Beaches

Mon 11/3

5:55 pm-11:30 am

2 stops17h 35m

$514

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Wed 10/8

3:50 pm-11:10 pm

1 stop6h 20m

$336

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Wed 10/8

4:40 pm-9:48 pm

1 stop28h 08m

$338

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Fri 10/31

12:35 pm-10:18 am

1 stop20h 43m

$341

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 13 results
1
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Best time to book a flight from Mexico City to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Mexico City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City to Panama City

What is the cheapest month to book a flight from Mexico City to Panama City, Florida?

Currently, January is the cheapest month in which you can book a flight from Mexico City to Panama City, Florida (average of $346). Flying from Mexico City to Panama City, Florida in March is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 11, 2025.
Get a feel of what it's like to fly with United Airlines from Mexico City to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,937 reviews

Boarding

7.7

Crew

8.1

Entertainment

7.1

Overall

7.4

Comfort

7.3

Food

6.6

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
United Airlines
7.4
Good
8,937 reviews
United Airlines
7.4
Good
8,937 reviews

Boarding

7.7

Crew

8.1

Entertainment

7.1

Overall

7.4

Comfort

7.3

Food

6.6

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.

Related info for your journey

Find useful and relevant information for your journey from Mexico City to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mexico City to Panama City, Florida?

    A quick flight from Mexico City to Panama City, Florida can take about 10h 45m. Delta provides one of the quickest options available for as low as $500. The distance from Mexico City to Panama City, Florida is about 1121 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Mexico City to Panama City, Florida round-trip?

    According to our current data, United Airlines ($468), offers the cheapest pricing from Mexico City to Panama City, Florida. United Airlines is currently priced 17% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Mexico City to Panama City, Florida one-way?

    One-way options have recently been found by users for as low as $336 on Delta. Other airlines that offer cheap prices include United Airlines from $338 and American Airlines from $341 one-way.

  • Can I find deals for flights from Mexico City to Panama City that include hotel bookings?

    Yes. In addition to deals on Mexico City to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to Panama City.

  • Can I find deals for business class flights from Mexico City to Panama City?

    Yes. Cheapflights offers flight deals from Mexico City to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City to Panama City, Florida?

    Currently, January is the cheapest month in which you can book a flight from Mexico City to Panama City, Florida (average of $346). Flying from Mexico City to Panama City, Florida in March is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

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Top airline flying from Mexico City to Panama City

Discover the top airline that operate flights from Mexico City to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$468Average$578FlexibilityNo cancel feeOn-time69%

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