HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama City

$351+ Cheap flights from Mexico City (MEX) to Panama City, FL (ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/22. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — ECP
May 5 — May 121
Mon 5/5
Mon 5/12
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Mexico City to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Mexico City to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Mexico City (MEX) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$446
(United Airlines)

One-way from

$351
(Delta)

Popular in

January

Cheapest in

July

Average price

$579
Provider with most accurate pricing for Mexico City Benito Juarez-Panama City NW Florida Beaches flight deals.
Search Deals
Provider most trusted by Cheapflights users for Mexico City Benito Juarez-Panama City NW Florida Beaches flights.
Search Deals
From Mexico City Benito Juarez to Panama City NW Florida Beaches
Search Deals
One-way flight from Mexico City Benito Juarez to Panama City NW Florida Beaches
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($48 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2025
Search Deals

Find flight deals from Mexico City to Panama City

Cheapest flights from Mexico City to Panama City
Explore the most affordable flight options available from Mexico City to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.

This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/811:35 amMEX - ECP
1 stop23h 50mUnited Airlines
Sun 5/115:01 pmECP - MEX
1 stop23h 39mUnited Airlines
Deal found 4/28$446
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/87:01 amMEX - ECP
2 stops11h 47mDelta
Sun 5/119:12 amECP - MEX
2 stops11h 18mDelta
Deal found 4/28$459
This Aeromexico deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/26:01 amMEX - ECP
2 stops12h 39mAeromexico
Sun 5/46:00 amECP - MEX
2 stops14h 15mAeromexico
Deal found 4/29$1,015
This WestJet deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure WestJet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/151:55 amMEX - ECP
2 stops16h 02mWestJet
Sat 8/231:30 pmECP - MEX
2 stops36h 28mWestJet
Deal found 4/28$1,375

Cheapflights Fare Finder

Customize your flight search to find flights from Mexico City to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
Use the filters below to find and compare flights from Mexico City to Panama City that are best for you.

Fly from

Mexico City

Fly to

Panama City

Route

Depart

Return

Price

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Thu 5/8

11:35 am-12:25 pm

1 stop23h 50m

Panama City NW Florida Beaches

Sun 5/11

5:01 pm-3:40 pm

1 stop23h 39m

$446

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Thu 5/8

7:01 am-7:48 pm

2 stops11h 47m

Panama City NW Florida Beaches

Sun 5/11

9:12 am-7:30 pm

2 stops11h 18m

$459

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Fri 5/2

6:01 am-7:40 pm

2 stops12h 39m

Panama City NW Florida Beaches

Sun 5/4

6:00 am-7:15 pm

2 stops14h 15m

$1,015

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Sun 6/15

1:55 am-6:57 pm

2 stops16h 02m

Panama City NW Florida Beaches

Sat 8/23

1:30 pm-12:58 am

2 stops36h 28m

$1,375

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Sun 6/22

8:40 am-11:21 pm

2 stops13h 41m

$351

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Sat 6/21

1:01 am-6:57 pm

2 stops16h 56m

$2,374

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Compare providers for flights from Mexico City to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Mexico City to Panama City in April.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*2 stars
ExpediaPrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Mexico City-Panama City, Florida flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Mexico City-Panama City, Florida flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Mexico City-Panama City, Florida flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Mexico City-Panama City, Florida flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Mexico City-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Mexico City to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Mexico City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City to Panama City

What is the cheapest month to book a flight from Mexico City to Panama City, Florida?

Currently, January is the cheapest month in which you can book a flight from Mexico City to Panama City, Florida (average of $346). Flying from Mexico City to Panama City, Florida in March is currently the most expensive (average of $461). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MEX to ECP?

Find hourly flight availability from Mexico City to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 30, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mexico City to Panama City, Florida as you normally would.

Rainfall in Panama City by month

Plan your trip to Panama City by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama City, Florida ranges from 2.8 - 7.9 inches per month. July is typically the wettest month, when rainfall can reach 7.9 in. May is typically the driest time to visit Panama City, Florida when rainfall is around 2.8 in.

Temperature in Panama City by month

Plan your trip to Panama City by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama City, Florida, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 53.6 F).

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated April 30, 2025.
Delta
8.0
Very good
7,929 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Elizabeth,Sep 2023

MEX - ATL

Food was cheap and not healthful. Entertainment was poor choices. Flight was rocky but not pilots fault.
Delta
8.0
Very good
7,929 reviews
Delta
8.0
Very good
7,929 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Elizabeth,Sep 2023

MEX - ATL

Food was cheap and not healthful. Entertainment was poor choices. Flight was rocky but not pilots fault.
Aeromexico
7.5
Good
1,698 reviews
Delta
8.0
Very good
7,929 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Elizabeth,Sep 2023

MEX - ATL

Food was cheap and not healthful. Entertainment was poor choices. Flight was rocky but not pilots fault.
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,929 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Elizabeth,Sep 2023

MEX - ATL

Food was cheap and not healthful. Entertainment was poor choices. Flight was rocky but not pilots fault.
WestJet
7.2
Good
2,823 reviews
Delta
8.0
Very good
7,929 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Elizabeth,Sep 2023

MEX - ATL

Food was cheap and not healthful. Entertainment was poor choices. Flight was rocky but not pilots fault.

Related info for your journey

Find useful and relevant information for your journey from Mexico City to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Mexico City to Panama City, Florida round-trip?

    According to our current data, United Airlines ($446), Delta ($459), and Aeromexico ($1,015) offers the cheapest pricing from Mexico City to Panama City, Florida. United Airlines is currently priced 22% below the average price you’ll pay for this route.

  • Can I find deals for flights from Mexico City to Panama City that include hotel bookings?

    Yes. In addition to deals on Mexico City to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to Panama City.

  • Can I find deals for business class flights from Mexico City to Panama City?

    Yes. Cheapflights offers flight deals from Mexico City to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City to Panama City, Florida?

    Currently, January is the cheapest month in which you can book a flight from Mexico City to Panama City, Florida (average of $346). Flying from Mexico City to Panama City, Florida in March is currently the most expensive (average of $461). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Mexico City?

Book flights to Mexico City if you plan to visit one of these locations
Mexico Beach

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from Mexico City to Panama City

Discover the top airline that operate flights from Mexico City to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$485Average$586FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.