Panama City

$353+ Cheap flights from Mexico City (MEX) to Panama City, FL (ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/1. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — ECP
Feb 26 — Mar 51
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Cheap flight deals from Mexico City to Panama City

Cheapest flights from Mexico City to Panama City
Explore the most affordable flight options available from Mexico City to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.

This Delta deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1511:15 am
MEX
-
ECP
1 stop10h 31m
Delta
Thu 10/1511:15 am
ECP
-
MEX
2 stops10h 50m
Delta
Deal found 1/25$524
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/149:35 am
MEX
-
ECP
2 stops26h 48m
United Airlines
Mon 4/2010:10 am
ECP
-
MEX
1 stop6h 30m
United Airlines
Deal found 1/26$530
This Aeromexico deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/273:15 pm
MEX
-
ECP
1 stop6h 32m
Aeromexico
Fri 10/306:00 am
ECP
-
MEX
2 stops14h 15m
Aeromexico
Deal found 1/26$549
This Aeromexico deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:05 am
MEX
-
ECP
2 stops14h 17m
Aeromexico
Mon 4/275:49 am
ECP
-
MEX
1 stop14h 51m
Aeromexico
Deal found 1/26$551
This Aeromexico deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/158:40 am
MEX
-
ECP
1 stop8h 11m
Aeromexico
Thu 10/157:45 am
ECP
-
MEX
1 stop14h 25m
Aeromexico
Deal found 1/25$581
This Aeromexico deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/239:05 am
MEX
-
ECP
2 stops10h 25m
Aeromexico
Mon 3/22:05 pm
ECP
-
MEX
1 stop6h 45m
Aeromexico
Deal found 1/25$584
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1410:55 am
MEX
-
ECP
2 stops10h 57m
American Airlines
Mon 4/207:21 am
ECP
-
MEX
2 stops15h 59m
American Airlines
Deal found 1/26$612
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/2311:20 am
MEX
-
ECP
1 stop12h 29m
American Airlines
Mon 3/27:19 am
ECP
-
MEX
1 stop14h 36m
American Airlines
Deal found 1/25$626
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2410:40 am
MEX
-
ECP
2 stops9h 42m
Delta
Mon 4/279:21 am
ECP
-
MEX
2 stops11h 49m
Delta
Deal found 1/26$631
This Delta deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/238:35 am
MEX
-
ECP
2 stops14h 04m
Delta
Mon 3/26:00 am
ECP
-
MEX
2 stops12h 45m
Delta
Deal found 1/25$672

Find flight deals from Mexico City to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Mexico City (MEX) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$530
(United Airlines)

One-way from

$353
(Aeromexico)

Popular in

December

Cheapest in

July

Average price

$593
Provider with most accurate pricing for Mexico City Benito Juarez-Panama City NW Florida Beaches flight deals.
Provider most trusted by Cheapflights users for Mexico City Benito Juarez-Panama City NW Florida Beaches flights.
From Mexico City Benito Juarez to Panama City NW Florida Beaches
One-way flight from Mexico City Benito Juarez to Panama City NW Florida Beaches
Highest demand for flights based on searches. 15% potential increase in price ($101 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($17 potential savings vs. average RT price).
Average for round-trip flights in January 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico City to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from Mexico City to Panama City that are best for you.

Fly from

Mexico City

Fly to

Panama City

Route

Depart

Return

Price

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Tue 4/14

4:40 pm-9:35 am

1 stop15h 55m

Panama City NW Florida Beaches

Mon 4/20

10:10 am-11:10 pm

1 stop14h 00m

$530

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Fri 4/24

6:05 am-9:22 pm

2 stops14h 17m

Panama City NW Florida Beaches

Mon 4/27

5:49 am-7:40 pm

1 stop14h 51m

$551

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Mon 2/23

9:05 am-7:30 pm

2 stops10h 25m

Panama City NW Florida Beaches

Mon 3/2

2:05 pm-8:50 pm

1 stop6h 45m

$584

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Mon 2/23

11:20 am-11:49 pm

1 stop12h 29m

Panama City NW Florida Beaches

Mon 3/2

7:19 am-9:55 pm

1 stop14h 36m

$626

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Fri 4/24

10:40 am-9:22 pm

2 stops9h 42m

Panama City NW Florida Beaches

Mon 4/27

9:21 am-8:10 pm

2 stops11h 49m

$631

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Mon 2/23

8:35 am-10:39 pm

2 stops14h 04m

Panama City NW Florida Beaches

Mon 3/2

6:00 am-6:45 pm

2 stops12h 45m

$672

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Wed 4/1

9:05 am-5:40 pm

1 stop7h 35m

$353

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Wed 4/1

9:05 am-7:47 pm

2 stops9h 42m

$354

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Tue 2/10

4:35 pm-10:40 pm

1 stop6h 05m

$405

Mexico CityPanama City

MEX - ECP

MEXECP

Mexico City Benito Juarez

Mon 2/9

12:35 pm-7:50 pm

1 stop7h 15m

$405

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/25

Showing 1-10 of 11 results
1
2

Compare providers for flights from Mexico City to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Mexico City to Panama City in January.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
ExpediaPrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Mexico City-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Mexico City-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Mexico City-Panama City, Florida flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Mexico City-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Mexico City-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Mexico City to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Mexico City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City to Panama City

What is the cheapest month to book a flight from Mexico City to Panama City, Florida?

Currently, August is the cheapest month in which you can book a flight from Mexico City to Panama City, Florida (average of $377). Flying from Mexico City to Panama City, Florida in December is currently the most expensive (average of $542). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated January 27, 2026.
Get a feel of what it's like to fly with United Airlines from Mexico City to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Overall

7.4

Food

6.6

Crew

8.1

Entertainment

7.1

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
6.0
Good

Gerry,Jan 2026

YVR - DEN

Seats were uncomfortable. Second leg of my flight on United had much more comfortable seats

Overall

7.4

Food

6.6

Crew

8.1

Entertainment

7.1

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
6.0
Good

Gerry,Jan 2026

YVR - DEN

Seats were uncomfortable. Second leg of my flight on United had much more comfortable seats

Related info for your journey

Find useful and relevant information for your journey from Mexico City to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Mexico City to Panama City, Florida?

    A quick flight from Mexico City to Panama City, Florida can take about 14h 17m. United Airlines provides one of the quickest options available for as low as $551. The distance from Mexico City to Panama City, Florida is about 1121 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Mexico City to Panama City, Florida round-trip?

    According to our current data, United Airlines ($468), offers the cheapest pricing from Mexico City to Panama City, Florida. United Airlines is currently priced 16% below the average price you’ll pay for this route.

  • Can I find deals for flights from Mexico City to Panama City that include hotel bookings?

    Yes. In addition to deals on Mexico City to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to Panama City.

  • Can I find deals for business class flights from Mexico City to Panama City?

    Yes. Cheapflights offers flight deals from Mexico City to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City to Panama City, Florida?

    Currently, August is the cheapest month in which you can book a flight from Mexico City to Panama City, Florida (average of $377). Flying from Mexico City to Panama City, Florida in December is currently the most expensive (average of $542). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

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Top airline flying from Mexico City to Panama City

Discover the top airline that operate flights from Mexico City to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$468Average$578FlexibilityNo cancel feeOn-time69%

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