$311+ Cheap flights from Harrisburg to Panama City, FL (MDT - ECP)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/9. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — ECP
Nov 24 — Dec 11
Round-trip
1 adult, Economy
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Find cheap flights from Harrisburg to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Harrisburg to Panama City
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Best
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Cheapest flights from Harrisburg to Panama CityExplore the most affordable flight options available from Harrisburg to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
Explore the most affordable flight options available from Harrisburg to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:17 am -
1 stop8h 00m
Tue 12/151:58 pm -
1 stop5h 56m
Deal found 10/20![United Airlines logo]()
$311
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/171:47 pm -
1 stop5h 45m
Sun 12/207:02 pm -
1 stop4h 10m
Deal found 10/25![American Airlines logo]()
$361
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:20 am -
2 stops7h 57m
Sun 12/131:58 pm -
1 stop5h 56m
Deal found 10/24![United Airlines logo]()
$364
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/136:17 am -
1 stop8h 00m
Sat 12/192:00 pm -
1 stop7h 47m
Deal found 10/20![United Airlines logo]()
$383
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:17 am -
1 stop8h 00m
Sun 12/131:58 pm -
1 stop5h 56m
Deal found 10/20![United Airlines logo]()
$435
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:00 am -
1 stop5h 30m
Thu 11/266:00 am -
1 stop5h 52m
Deal found 10/23![Delta logo]()
$479
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:33 pm -
1 stop5h 44m
Mon 12/146:59 pm -
1 stop3h 49m
Deal found 10/20![Delta logo]()
$500
Best flights from Harrisburg to Panama CityDiscover carefully curated flight deals from Harrisburg to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
Discover carefully curated flight deals from Harrisburg to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/186:20 am -
2 stops10h 45m
Sat 1/302:10 pm -
1 stop5h 39m
Deal found 10/20![United Airlines logo]()
$340
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/171:47 pm -
1 stop5h 45m
Sun 12/207:02 pm -
1 stop4h 10m
Deal found 10/25![American Airlines logo]()
$361
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/206:00 am -
1 stop5h 15m
Fri 2/264:10 pm -
1 stop6h 28m
Deal found 10/21![Delta logo]()
$398
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/311:56 am -
2 stops6h 21m
Wed 2/1710:51 am -
1 stop5h 23m
Deal found 10/23![American Airlines logo]()
$401
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/96:20 am -
1 stop8h 07m
Tue 1/122:10 pm -
1 stop5h 39m
Deal found 10/23![United Airlines logo]()
$411
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/236:00 am -
2 stops9h 17m
Tue 3/22:10 pm -
1 stop6h 10m
Deal found 10/21![United Airlines logo]()
$416
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:17 am -
1 stop8h 00m
Sun 12/131:58 pm -
1 stop5h 56m
Deal found 10/21![United Airlines logo]()
$459
Last-minute flights from Harrisburg to Panama CityDiscover last-minute flight deals from Harrisburg to Panama City. Data last updated October 25, 2026 and is based on user searches.
Discover last-minute flight deals from Harrisburg to Panama City. Data last updated October 25, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:15 am -
2 stops7h 54m
Wed 11/119:06 am -
2 stops11h 27m
Deal found 10/23![United Airlines logo]()
$595
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:15 am -
2 stops7h 54m
Tue 11/109:06 am -
2 stops8h 51m
Deal found 10/24![United Airlines logo]()
$793
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:15 am -
2 stops9h 13m
Thu 11/129:06 am -
2 stops8h 51m
Deal found 10/24![United Airlines logo]()
$767
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:48 pm -
1 stop7h 00m
Fri 11/137:01 pm -
1 stop4h 15m
Deal found 10/22![American Airlines logo]()
$651
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:00 am -
1 stop5h 30m
Thu 11/266:00 am -
1 stop5h 52m
Deal found 10/23![Delta logo]()
$479
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/191:57 pm -
2 stops10h 50m
Thu 11/267:25 am -
1 stop4h 40m
Deal found 10/23![American Airlines logo]()
$522
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/225:46 pm -
1 stop7h 01m
Fri 11/277:25 am -
1 stop6h 37m
Deal found 10/21![American Airlines logo]()
$703
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:22 pm -
1 stop6h 02m
Fri 11/277:15 am -
1 stop15h 35m
Deal found 10/21![Delta logo]()
$594
One-way flights from Harrisburg to Panama CitySearch for one-way flight options from Harrisburg to Panama City. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
Search for one-way flight options from Harrisburg to Panama City. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/216:00 am -
1 stop5h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![American Airlines logo]()
$326
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/216:03 am -
3 stops16h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![United Airlines logo]()
$873
Find flight deals from Harrisburg to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $311 (United Airlines) |
Popular in | October |
Cheapest in | January |
Average price | $696 |
Cheapflights Fare Finder
Customize your flight search to find flights from Harrisburg to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
Use the filters below to find and compare flights from Harrisburg to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
HarrisburgPanama City
MDT Harrisburg - ECP Panama City NW Florida Beaches
MDTECP
Harrisburg
Mon 12/21
3:07 pm-11:40 pm
2 stops9h 33m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$331
HarrisburgPanama City
MDT Harrisburg - ECP Panama City NW Florida Beaches
MDTECP
Harrisburg
Mon 1/18
6:20 am-4:05 pm
2 stops10h 45m
Panama City NW Florida Beaches
Sat 1/30
2:10 pm-8:49 pm
1 stop5h 39m
$340
HarrisburgPanama City
MDT Harrisburg - ECP Panama City NW Florida Beaches
MDTECP
Harrisburg
Thu 12/17
1:47 pm-6:32 pm
1 stop5h 45m
Panama City NW Florida Beaches
Sun 12/20
7:02 pm-12:12 am
1 stop4h 10m
$361
HarrisburgPanama City
MDT Harrisburg - ECP Panama City NW Florida Beaches
MDTECP
Harrisburg
Sat 2/20
6:00 am-10:15 am
1 stop5h 15m
Panama City NW Florida Beaches
Fri 2/26
4:10 pm-11:38 pm
1 stop6h 28m
$398
HarrisburgPanama City
MDT Harrisburg - ECP Panama City NW Florida Beaches
MDTECP
Harrisburg
Wed 2/3
11:56 am-5:17 pm
2 stops6h 21m
Panama City NW Florida Beaches
Wed 2/17
10:51 am-5:14 pm
1 stop5h 23m
$401
HarrisburgPanama City
MDT Harrisburg - ECP Panama City NW Florida Beaches
MDTECP
Harrisburg
Sat 1/9
6:20 am-1:27 pm
1 stop8h 07m
Panama City NW Florida Beaches
Tue 1/12
2:10 pm-8:49 pm
1 stop5h 39m
$411
HarrisburgPanama City
MDT Harrisburg - ECP Panama City NW Florida Beaches
MDTECP
Harrisburg
Tue 2/23
6:00 am-2:17 pm
2 stops9h 17m
Panama City NW Florida Beaches
Tue 3/2
2:10 pm-9:20 pm
1 stop6h 10m
$416
HarrisburgPanama City
MDT Harrisburg - ECP Panama City NW Florida Beaches
MDTECP
Harrisburg
Thu 12/10
6:17 am-1:17 pm
1 stop8h 00m
Panama City NW Florida Beaches
Sun 12/13
1:58 pm-8:54 pm
1 stop5h 56m
$459
HarrisburgPanama City
MDT Harrisburg - ECP Panama City NW Florida Beaches
MDTECP
Harrisburg
Mon 12/21
6:03 am-9:58 pm
3 stops16h 55m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$873
Sorted by cheapest first
Compare providers for flights from Harrisburg to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Harrisburg to Panama City in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Harrisburg-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Harrisburg-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Harrisburg-Panama City, Florida flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Harrisburg-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harrisburg-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Harrisburg to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Harrisburg with our price prediction graph.
MDT-ECP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Harrisburg to Panama City
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated October 25, 2026.
See what other customers who have flown with Delta and American Airlines from Harrisburg to Panama City have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Comfort
7.8
Boarding
8.1
Food
7.2
Crew
8.5
Overall
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Entertainment
7.8
Comfort
7.8
Boarding
8.1
Food
7.2
Crew
8.5
Overall
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Entertainment
7.8
Comfort
7.8
Boarding
8.1
Food
7.2
Crew
8.5
Overall
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Related info for your journey
Find useful and relevant information for your journey from Harrisburg to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
Complete your trip to Panama City by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Harrisburg to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Harrisburg and Panama City flights
Browse other Harrisburg and Panama City flight options. Last updated on October 25, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Harrisburg to Panama City
Discover the top 2 airlines that operate flights from Harrisburg to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$273 | Average$413 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$290 | Average$465 | FlexibilityNo cancel fee | On-time71% |