$271+ Cheap flights from Panama City, FL to Harrisburg (ECP - MDT)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — MDT
Oct 7 — Oct 141
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to Harrisburg with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to Harrisburg
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Best
Last-minute
One-way
Cheapest flights from Panama City to HarrisburgExplore the most affordable flight options available from Panama City to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
Explore the most affordable flight options available from Panama City to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:42 pm -
1 stop4h 42m
Sat 10/245:49 pm -
1 stop7h 04m
Deal found 9/5![American Airlines logo]()
$271
This Delta deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:40 pm -
1 stop4h 59m
Wed 11/116:23 pm -
1 stop6h 01m
Deal found 9/4![Delta logo]()
$291
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:37 pm -
1 stop5h 02m
Wed 11/116:23 pm -
1 stop6h 01m
Deal found 9/3![Delta logo]()
$296
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/711:54 am -
2 stops10h 04m
Wed 11/1111:25 am -
1 stop6h 44m
Deal found 9/3![American Airlines logo]()
$404
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:10 am -
1 stop4h 47m
Wed 11/117:45 am -
2 stops10h 24m
Deal found 9/3![American Airlines logo]()
$436
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/179:23 am -
1 stop7h 00m
Sun 9/206:09 pm -
1 stop6h 16m
Deal found 9/3![Delta logo]()
$530
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/98:29 am -
2 stops12h 50m
Wed 9/1611:17 am -
1 stop7h 15m
Deal found 9/5![American Airlines logo]()
$553
Best flights from Panama City to HarrisburgDiscover carefully curated flight deals from Panama City to Harrisburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
Discover carefully curated flight deals from Panama City to Harrisburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
This Delta deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:40 pm -
1 stop4h 59m
Wed 11/116:23 pm -
1 stop6h 01m
Deal found 9/4![Delta logo]()
$291
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/272:08 pm -
1 stop5h 47m
Sat 1/306:30 am -
1 stop7h 47m
Deal found 9/2![United Airlines logo]()
$351
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:37 pm -
1 stop5h 02m
Wed 11/116:23 pm -
1 stop6h 01m
Deal found 9/3![Delta logo]()
$296
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:37 pm -
1 stop5h 02m
Wed 11/116:23 pm -
1 stop6h 01m
Deal found 9/3![Delta logo]()
$296
Last-minute flights from Panama City to HarrisburgDiscover last-minute flight deals from Panama City to Harrisburg. Data last updated September 7, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Harrisburg. Data last updated September 7, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/98:29 am -
2 stops12h 50m
Wed 9/1611:17 am -
1 stop7h 15m
Deal found 9/5![American Airlines logo]()
$553
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/179:23 am -
1 stop7h 00m
Sun 9/206:09 pm -
1 stop6h 16m
Deal found 9/3![Delta logo]()
$530
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1711:41 am -
2 stops10h 49m
Sun 9/206:30 am -
1 stop7h 43m
Deal found 9/3![United Airlines logo]()
$634
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:20 am -
2 stops9h 32m
Sat 10/106:30 am -
2 stops16h 48m
Deal found 9/5![United Airlines logo]()
$643
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:20 am -
2 stops9h 32m
Mon 11/308:13 pm -
2 stops18h 04m
Deal found 9/5![United Airlines logo]()
$672
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:42 pm -
1 stop4h 42m
Sat 10/245:49 pm -
1 stop7h 04m
Deal found 9/5![American Airlines logo]()
$271
One-way flights from Panama City to HarrisburgSearch for one-way flight options from Panama City to Harrisburg. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
Search for one-way flight options from Panama City to Harrisburg. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:30 am -
2 stops11h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![United Airlines logo]()
$279
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:05 pm -
1 stop4h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![American Airlines logo]()
$306
Find flight deals from Panama City to Harrisburg
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Harrisburg (MDT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $271 (American Airlines) |
Popular in | April |
Cheapest in | February |
Average price | $416 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Harrisburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
Use the filters below to find and compare flights from Panama City to Harrisburg that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityHarrisburg
ECP Panama City NW Florida Beaches - MDT Harrisburg
ECPMDT
Panama City NW Florida Beaches
Wed 11/11
11:30 am-11:44 pm
2 stops11h 14m
Harrisburg
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$279
Panama CityHarrisburg
ECP Panama City NW Florida Beaches - MDT Harrisburg
ECPMDT
Panama City NW Florida Beaches
Sat 11/7
5:40 pm-11:39 pm
1 stop4h 59m
Harrisburg
Wed 11/11
6:23 pm-11:24 pm
1 stop6h 01m
$291
Panama CityHarrisburg
ECP Panama City NW Florida Beaches - MDT Harrisburg
ECPMDT
Panama City NW Florida Beaches
Fri 11/6
5:37 pm-11:39 pm
1 stop5h 02m
Harrisburg
Wed 11/11
6:23 pm-11:24 pm
1 stop6h 01m
$296
Panama CityHarrisburg
ECP Panama City NW Florida Beaches - MDT Harrisburg
ECPMDT
Panama City NW Florida Beaches
Thu 11/5
5:37 pm-11:39 pm
1 stop5h 02m
Harrisburg
Wed 11/11
6:23 pm-11:24 pm
1 stop6h 01m
$296
Quickest round-trip
Panama CityHarrisburg
ECP Panama City NW Florida Beaches - MDT Harrisburg
ECPMDT
Panama City NW Florida Beaches
Sat 11/7
6:05 pm-11:21 pm
1 stop4h 16m
Harrisburg
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$306
Panama CityHarrisburg
ECP Panama City NW Florida Beaches - MDT Harrisburg
ECPMDT
Panama City NW Florida Beaches
Wed 1/27
2:08 pm-8:55 pm
1 stop5h 47m
Harrisburg
Sat 1/30
6:30 am-1:17 pm
1 stop7h 47m
$351
Sorted by cheapest first
Compare providers for flights from Panama City to Harrisburg
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Harrisburg in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City, Florida-Harrisburg flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-Harrisburg flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Harrisburg flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City, Florida-Harrisburg flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Harrisburg flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to Harrisburg
Have a flexible travel schedule? Discover the best time to fly to Harrisburg from Panama City with our price prediction graph.
ECP-MDT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Harrisburg
What is the cheapest month to book a flight from Panama City, Florida to Harrisburg?
Currently, February is the cheapest month in which you can book a flight from Panama City, Florida to Harrisburg (average of $243). Flying from Panama City, Florida to Harrisburg in April is currently the most expensive (average of $1,063). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Panama City, Florida to Harrisburg?
Airfare is below average for this route at the moment.
Panama City, Florida to Harrisburg flights typically cost between $360 and $473 in October.The cheapest round-trip price found within the last 5 days was $271 on American Airlines (Oct 21-Oct 24).
Reviews of airlines servicing Harrisburg
Get insights into the airlines that provide service to Harrisburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Harrisburg. Reviews last updated September 7, 2026.
Peruse reviews from past customers who have flown with Delta and American Airlines from Panama City to Harrisburg to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Food
7.2
Overall
7.8
Crew
8.5
Comfort
7.8
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Entertainment
7.8
Food
7.2
Overall
7.8
Crew
8.5
Comfort
7.8
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Entertainment
7.8
Food
7.2
Overall
7.8
Crew
8.5
Comfort
7.8
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from Panama City to Harrisburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Harrisburg?
Book flights to Harrisburg if you plan to visit one of these locationsHershey
Mechanicsburg
Camp Hill
Carlisle
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Panama City and Harrisburg flights
Browse other Panama City and Harrisburg flight options. Last updated on September 7, 2026.
Other flights from Panama City
Browse through other flights departing from Panama City. Flights are based on user searches made on Cheapflights and were last updated on September 7, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Panama City to Harrisburg
Discover the top 2 airlines that operate flights from Panama City to Harrisburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$243 | Average$420 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$260 | Average$368 | FlexibilityNo cancel fee | On-timeN/A |