How long is the flight from Panama City, Florida to Harrisburg?

A quick flight from Panama City, Florida to Harrisburg can take about 4h 24m. American Airlines provides one of the quickest options available for as low as $316. The distance from Panama City, Florida to Harrisburg is about 848 mi. Both multi-stop and nonstop flights can be found to your destination and back.

What are the cheapest airlines flying from Panama City, Florida to Harrisburg round-trip?

Cheapflights users have booked flights from Panama City, Florida to Harrisburg round-trip from $243. Another airline that can offer you cheap pricing is Delta. These flights start at 43% lower than the current average price 3 months from now.

In terms of precipitation, rainfall in Harrisburg ranges from 2.7 - 4.1 inches per month. May is typically the wettest month, when rainfall can reach 4.1 in. February is typically the driest time to visit Harrisburg when rainfall is around 2.7 in.

If weather is an important factor for your trip to Harrisburg, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 30.2 F).

What is the cheapest time of day to fly from ECP to MDT?

When flying from Panama City, Florida to Harrisburg, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Most accurate provider : When it comes to deals on Panama City, Florida-Harrisburg flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-Harrisburg flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Harrisburg flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Panama City, Florida-Harrisburg flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Harrisburg flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Panama City to Harrisburg that include hotel bookings?

Yes. In addition to deals on Panama City to Harrisburg flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Panama City to Harrisburg?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Harrisburg.

Can I find deals for business class flights from Panama City to Harrisburg?

Yes. Cheapflights offers flight deals from Panama City to Harrisburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$316+ Cheap Flights from Panama City, FL to Harrisburg

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Cheap flight deals from Panama City to Harrisburg

Cheapest

Best

Last-minute

One-way

Cheapest flights from Panama City to Harrisburg
Explore the most affordable flight options available from Panama City to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.

Wed 10/287:15 am -

1 stop5h 03m

Sun 11/15:00 am -

1 stop6h 42m

Deal found 9/15

$316

Fri 10/166:42 pm -

1 stop4h 42m

Sun 10/185:00 am -

1 stop6h 28m

Deal found 9/15

$391

Fri 10/27:35 am -

1 stop5h 44m

Sun 10/46:09 pm -

1 stop6h 16m

Deal found 9/17

$444

Thu 9/176:00 am -

1 stop4h 03m

Sun 9/206:09 pm -

1 stop6h 16m

Deal found 9/14

$520

Thu 10/111:41 am -

2 stops10h 48m

Mon 10/56:30 am -

1 stop7h 33m

Deal found 9/16

$545

Fri 10/21:32 pm -

2 stops8h 39m

Sun 10/45:00 am -

1 stop6h 24m

Deal found 9/17

$612

Best flights from Panama City to Harrisburg
Discover carefully curated flight deals from Panama City to Harrisburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.

Wed 1/272:08 pm -

1 stop5h 47m

Sat 1/306:30 am -

1 stop7h 47m

Deal found 9/15

$371

Fri 10/27:35 am -

1 stop5h 44m

Sun 10/46:09 pm -

1 stop6h 16m

Deal found 9/17

$444

Wed 10/287:15 am -

2 stops10h 39m

Sun 11/19:36 am -

2 stops9h 55m

Deal found 9/15

$590

Wed 1/202:08 pm -

1 stop5h 47m

Sat 1/236:30 am -

1 stop7h 47m

Deal found 9/16

$371

Fri 10/21:32 pm -

2 stops8h 39m

Sun 10/48:30 am -

2 stops10h 38m

Deal found 9/17

$672

Last-minute flights from Panama City to Harrisburg
Discover last-minute flight deals from Panama City to Harrisburg. Data last updated September 17, 2026 and is based on user searches.

Thu 9/176:00 am -

1 stop4h 03m

Sun 9/206:09 pm -

1 stop6h 16m

Deal found 9/14

$520

Thu 10/111:41 am -

2 stops10h 48m

Mon 10/56:30 am -

1 stop7h 33m

Deal found 9/16

$545

Fri 10/27:35 am -

1 stop5h 44m

Sun 10/46:09 pm -

1 stop6h 16m

Deal found 9/17

$444

Fri 10/21:32 pm -

2 stops8h 39m

Sun 10/45:00 am -

1 stop6h 24m

Deal found 9/17

$612

Fri 10/166:42 pm -

1 stop4h 42m

Sun 10/185:00 am -

1 stop6h 28m

Deal found 9/15

$391

Wed 10/287:15 am -

1 stop5h 03m

Sun 11/15:00 am -

1 stop6h 42m

Deal found 9/15

$316

Find flight deals from Panama City to Harrisburg

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$316 (American Airlines)
One-way from	$316 (Delta)
Popular in	April
Cheapest in	February
Average price	$416

Provider with most accurate pricing for Panama City NW Florida Beaches-Harrisburg flight deals.

Search Deals

Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-Harrisburg flights.

Search Deals

From Panama City NW Florida Beaches to Harrisburg

Search Deals

One-way flight from Panama City NW Florida Beaches to Harrisburg

Search Deals

Highest demand for flights based on searches. 28% potential increase in price ($173 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 15% potential price decrease ($58 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in September 2026

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Panama City to Harrisburg that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

Panama CityHarrisburg

ECP Panama City NW Florida Beaches - MDT Harrisburg

ECPMDT

Panama City NW Florida Beaches

Fri 10/16

6:00 am-10:59 am

1 stop3h 59m

Harrisburg

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$316

Panama CityHarrisburg

ECP Panama City NW Florida Beaches - MDT Harrisburg

ECPMDT

Panama City NW Florida Beaches

Wed 1/27

2:08 pm-8:55 pm

1 stop5h 47m

Harrisburg

Sat 1/30

6:30 am-1:17 pm

1 stop7h 47m

$371

Panama CityHarrisburg

ECP Panama City NW Florida Beaches - MDT Harrisburg

ECPMDT

Panama City NW Florida Beaches

Wed 1/20

2:08 pm-8:55 pm

1 stop5h 47m

Harrisburg

Sat 1/23

6:30 am-1:17 pm

1 stop7h 47m

$371

Panama CityHarrisburg

ECP Panama City NW Florida Beaches - MDT Harrisburg

ECPMDT

Panama City NW Florida Beaches

Fri 10/2

7:35 am-2:19 pm

1 stop5h 44m

Harrisburg

Sun 10/4

6:09 pm-11:25 pm

1 stop6h 16m

$444

Panama CityHarrisburg

ECP Panama City NW Florida Beaches - MDT Harrisburg

ECPMDT

Panama City NW Florida Beaches

Wed 10/28

7:15 am-6:54 pm

2 stops10h 39m

Harrisburg

Sun 11/1

9:36 am-6:31 pm

2 stops9h 55m

$590

Panama CityHarrisburg

ECP Panama City NW Florida Beaches - MDT Harrisburg

ECPMDT

Panama City NW Florida Beaches

Fri 10/2

1:32 pm-11:11 pm

2 stops8h 39m

Harrisburg

Sun 10/4

8:30 am-6:08 pm

2 stops10h 38m

$672

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Sorted by cheapest first

Compare providers for flights from Panama City to Harrisburg

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Harrisburg in September.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy1 star	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Panama City, Florida-Harrisburg flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-Harrisburg flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Harrisburg flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Panama City, Florida-Harrisburg flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Harrisburg flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Harrisburg

Have a flexible travel schedule? Discover the best time to fly to Harrisburg from Panama City with our price prediction graph.

ECP-MDT

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Harrisburg

What is the cheapest month to book a flight from Panama City, Florida to Harrisburg?

Currently, February is the cheapest month in which you can book a flight from Panama City, Florida to Harrisburg (average of $243). Flying from Panama City, Florida to Harrisburg in April is currently the most expensive (average of $1,063). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Harrisburg

Peruse reviews from past customers who have flown with Delta and American Airlines from Panama City to Harrisburg to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.8

Good

8,579 reviews

Reviews

1 / 20

8.0

Excellent

Jorge,Aug 2026

TPA - ATL

Although I still enjoy flying Delta, the overall flying experience feels cheapened. But I guess that is true of most, if not all american carriers.

Delta

7.8

Good

8,579 reviews

Delta

7.8

Good

8,579 reviews

Reviews

1 / 20

8.0

Excellent

Jorge,Aug 2026

TPA - ATL

Although I still enjoy flying Delta, the overall flying experience feels cheapened. But I guess that is true of most, if not all american carriers.

American Airlines

7.1

Good

12,075 reviews

Delta

7.8

Good

8,579 reviews

Reviews

1 / 20

8.0

Excellent

Jorge,Aug 2026

TPA - ATL

Although I still enjoy flying Delta, the overall flying experience feels cheapened. But I guess that is true of most, if not all american carriers.

Related info for your journey

How long is the flight from Panama City, Florida to Harrisburg?
A quick flight from Panama City, Florida to Harrisburg can take about 4h 24m. American Airlines provides one of the quickest options available for as low as $316. The distance from Panama City, Florida to Harrisburg is about 848 mi. Both multi-stop and nonstop flights can be found to your destination and back.
What are the cheapest airlines flying from Panama City, Florida to Harrisburg round-trip?
Cheapflights users have booked flights from Panama City, Florida to Harrisburg round-trip from $243. Another airline that can offer you cheap pricing is Delta. These flights start at 43% lower than the current average price 3 months from now.
Can I find deals for flights from Panama City to Harrisburg that include hotel bookings?
Yes. In addition to deals on Panama City to Harrisburg flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Panama City to Harrisburg?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Harrisburg.
Can I find deals for business class flights from Panama City to Harrisburg?
Yes. Cheapflights offers flight deals from Panama City to Harrisburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Panama City, Florida to Harrisburg?
Currently, February is the cheapest month in which you can book a flight from Panama City, Florida to Harrisburg (average of $243). Flying from Panama City, Florida to Harrisburg in April is currently the most expensive (average of $1,063). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 2 airlines flying from Panama City to Harrisburg

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$243	Average$420	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$260	Average$368	FlexibilityNo cancel fee	On-timeN/A

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$316+ Cheap flights from Panama City, FL to Harrisburg (ECP - MDT)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/28. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Panama City to Harrisburg with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Panama City to Harrisburg

Cheapest flights from Panama City to HarrisburgExplore the most affordable flight options available from Panama City to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.

Explore the most affordable flight options available from Panama City to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.

Best flights from Panama City to HarrisburgDiscover carefully curated flight deals from Panama City to Harrisburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.

Discover carefully curated flight deals from Panama City to Harrisburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.

Last-minute flights from Panama City to HarrisburgDiscover last-minute flight deals from Panama City to Harrisburg. Data last updated September 17, 2026 and is based on user searches.

Discover last-minute flight deals from Panama City to Harrisburg. Data last updated September 17, 2026 and is based on user searches.

One-way flights from Panama City to HarrisburgSearch for one-way flight options from Panama City to Harrisburg. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.

Search for one-way flight options from Panama City to Harrisburg. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.

Find flight deals from Panama City to Harrisburg

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Panama City to Harrisburg that are best for you.

Compare providers for flights from Panama City to Harrisburg

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Harrisburg in September.

Best time to book a flight from Panama City to Harrisburg

Have a flexible travel schedule? Discover the best time to fly to Harrisburg from Panama City with our price prediction graph.

Cheapflights Insights

What is the cheapest month to book a flight from Panama City, Florida to Harrisburg?

Reviews of airlines servicing Harrisburg

Peruse reviews from past customers who have flown with Delta and American Airlines from Panama City to Harrisburg to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

How long is the flight from Panama City, Florida to Harrisburg?

What are the cheapest airlines flying from Panama City, Florida to Harrisburg round-trip?

Can I find deals for flights from Panama City to Harrisburg that include hotel bookings?

How can I find direct flights from Panama City to Harrisburg?

Can I find deals for business class flights from Panama City to Harrisburg?

What is the cheapest month to book a flight from Panama City, Florida to Harrisburg?

Traveling to a place near Harrisburg?

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Alternative routes for Panama City to Harrisburg

See prices for flight routes from nearby airports that may be better suited for you.

Complete your trip

Complete your trip to Harrisburg by adding a car rental and/or hotel reservation to your travel itinerary.

Search flights from Panama City to Harrisburg by cabin class

Find flights from Panama City to Harrisburg, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Panama City and Harrisburg flights

Browse other Panama City and Harrisburg flight options. Last updated on September 17, 2026.

Other flights from Panama City

Browse through other flights departing from Panama City. Flights are based on user searches made on Cheapflights and were last updated on September 17, 2026.

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Top 2 airlines flying from Panama City to Harrisburg

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Cheapest flights from Panama City to Harrisburg
Explore the most affordable flight options available from Panama City to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.

Best flights from Panama City to Harrisburg
Discover carefully curated flight deals from Panama City to Harrisburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.

Last-minute flights from Panama City to Harrisburg
Discover last-minute flight deals from Panama City to Harrisburg. Data last updated September 17, 2026 and is based on user searches.

One-way flights from Panama City to Harrisburg
Search for one-way flight options from Panama City to Harrisburg. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.