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Panama City

$254+ Cheap flights from Harrisburg to Panama City, FL (MDT - ECP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/27. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — ECP
Sep 2 — Sep 91
Tue 9/2
Tue 9/9
1 adult, Economy
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Cheapflights Tip: The best prices from Harrisburg to Panama City NW Florida Beaches are usually found in July or September, booked 21 days in advance, depart on a Monday or Tuesday and return on a Wednesday

Cheap flight deals from Harrisburg to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 28, 2025.

Round-trip from

$254
(Delta)

Popular in

February

Cheapest in

July

Average price

$318
From Harrisburg to Panama City NW Florida Beaches
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($29 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in August 2025
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Find flight deals from Harrisburg to Panama City

Cheapest flights from Harrisburg to Panama City
Explore the most affordable flight options available from Harrisburg to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 28, 2025.

This Delta deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2712:28 pmMDT - ECP
2 stops7h 05mDelta
Wed 10/111:00 amECP - MDT
1 stop5h 28mDelta
Deal found 8/27$254
This Delta deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/207:05 pmMDT - ECP
1 stop4h 52mDelta
Mon 11/244:26 pmECP - MDT
1 stop5h 48mDelta
Deal found 8/26$308
This Delta deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/36:23 pmMDT - ECP
1 stop5h 40mDelta
Wed 10/85:32 pmECP - MDT
1 stop4h 36mDelta
Deal found 8/28$314
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/137:31 pmMDT - ECP
1 stop5h 18mAmerican Airlines
Sat 11/157:15 amECP - MDT
1 stop6h 46mAmerican Airlines
Deal found 8/27$318
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/46:30 amMDT - ECP
2 stops10h 46mUnited Airlines
Sat 10/111:55 pmECP - MDT
1 stop6h 30mUnited Airlines
Deal found 8/27$324
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/310:38 amMDT - ECP
2 stops7h 58mAmerican Airlines
Wed 10/86:44 amECP - MDT
2 stops9h 29mAmerican Airlines
Deal found 8/28$328
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1210:30 amMDT - ECP
2 stops10h 46mUnited Airlines
Mon 9/151:44 pmECP - MDT
1 stop6h 31mUnited Airlines
Deal found 8/26$334
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/301:55 pmMDT - ECP
1 stop5h 19mAmerican Airlines
Sun 8/315:30 amECP - MDT
1 stop5h 00mAmerican Airlines
Deal found 8/27$339

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 28, 2025.
Use the filters below to find and compare flights from Harrisburg to Panama City that are best for you.

Fly from

Harrisburg

Fly to

Panama City

Route

Depart

Return

Price

HarrisburgPanama City

MDT - ECP

MDTECP

Harrisburg

Sat 9/27

12:28 pm-6:33 pm

2 stops7h 05m

Panama City NW Florida Beaches

Wed 10/1

11:00 am-5:28 pm

1 stop5h 28m

$254

HarrisburgPanama City

MDT - ECP

MDTECP

Harrisburg

Thu 11/20

7:05 pm-10:57 pm

1 stop4h 52m

Panama City NW Florida Beaches

Mon 11/24

4:26 pm-11:14 pm

1 stop5h 48m

$308

HarrisburgPanama City

MDT - ECP

MDTECP

Harrisburg

Fri 10/3

6:23 pm-11:03 pm

1 stop5h 40m

Panama City NW Florida Beaches

Wed 10/8

5:32 pm-11:08 pm

1 stop4h 36m

$314

HarrisburgPanama City

MDT - ECP

MDTECP

Harrisburg

Thu 11/13

7:31 pm-11:49 pm

1 stop5h 18m

Panama City NW Florida Beaches

Sat 11/15

7:15 am-3:01 pm

1 stop6h 46m

$318

HarrisburgPanama City

MDT - ECP

MDTECP

Harrisburg

Sat 10/4

8:15 am-1:05 pm

1 stop5h 50m

Panama City NW Florida Beaches

Sat 10/11

1:55 pm-9:25 pm

1 stop6h 30m

$319

HarrisburgPanama City

MDT - ECP

MDTECP

Harrisburg

Mon 9/1

5:55 pm-11:29 pm

1 stop6h 34m

$441

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/26

Best time to book a flight from Harrisburg to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Panama City

How far ahead should I book a flight from Harrisburg to Panama City, Florida?

Use this chart to determine the optimal time to book a round-trip flight from Harrisburg to Panama City. Price data was last updated on August 22, 2025.

The price you pay for your flight from Harrisburg to Panama City, Florida may vary depending on when you book. For the best chance of a lower fare, look to book 20 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Harrisburg to Panama City, Florida?

Currently, January is the cheapest month in which you can book a flight from Harrisburg to Panama City, Florida (average of $346). Flying from Harrisburg to Panama City, Florida in March is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDT to ECP?

Find hourly flight availability from Harrisburg to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 28, 2025.

A simple way to save on the total cost of your ticket is to fly from Harrisburg to Panama City, Florida in the afternoon. If you’re flexible enough to do this you can expect to save up to 32% on your trip compared to booking a flight at noon.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated August 28, 2025.
See what other customers who have flown with Delta and American Airlines from Harrisburg to Panama City have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,977 reviews

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Delta
8.0
Very good
7,977 reviews
Delta
8.0
Very good
7,977 reviews

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,977 reviews

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Harrisburg to Panama City, Florida?

    A quick flight from Harrisburg to Panama City, Florida can take about 7h 05m. Delta provides one of the quickest options available for as low as $254. There are 848 mi between Harrisburg and Panama City, Florida.

  • What are the cheapest airlines flying from Harrisburg to Panama City, Florida round-trip?

    Cheapflights users have booked flights from Harrisburg to Panama City, Florida round-trip from $248. Another airline that can offer you cheap pricing is American Airlines. Delta is 34% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Harrisburg to Panama City that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Panama City.

  • Can I find deals for business class flights from Harrisburg to Panama City?

    Yes. Cheapflights offers flight deals from Harrisburg to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to Panama City, Florida?

    Currently, January is the cheapest month in which you can book a flight from Harrisburg to Panama City, Florida (average of $346). Flying from Harrisburg to Panama City, Florida in March is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

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Top 2 airlines flying from Harrisburg to Panama City

Discover the top 2 airlines that operate flights from Harrisburg to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$248Average$361FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$253Average$403FlexibilityNo cancel feeOn-time71%

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