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Panama City

$249+ Cheap flights from Harrisburg to Panama City, FL (MDT - ECP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/9. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — ECP
Jan 7 — Jan 141
Wed 1/7
Wed 1/14
1 adult, Economy
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Cheap flight deals from Harrisburg to Panama City

Cheapest flights from Harrisburg to Panama City
Explore the most affordable flight options available from Harrisburg to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 8, 2025.

This United Airlines deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/226:30 amMDT - ECP
1 stop7h 57mUnited Airlines
Fri 12/269:52 amECP - MDT
2 stops13h 15mUnited Airlines
Deal found 12/6$577
This United Airlines deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1010:45 amMDT - ECP
2 stops12h 04mUnited Airlines
Fri 12/123:00 pmECP - MDT
2 stops26h 54mUnited Airlines
Deal found 12/6$677
This American Airlines deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/107:10 amMDT - ECP
2 stops10h 37mAmerican Airlines
Fri 12/125:50 pmECP - MDT
1 stop16h 22mAmerican Airlines
Deal found 12/6$834
This American Airlines deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/275:00 amMDT - ECP
1 stop19h 58mAmerican Airlines
Fri 1/24:09 pmECP - MDT
1 stop7h 10mAmerican Airlines
Deal found 12/6$1,047
This United Airlines deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:30 amMDT - ECP
2 stops40h 24mUnited Airlines
Fri 1/26:15 amECP - MDT
2 stops16h 52mUnited Airlines
Deal found 12/6$1,124
This American Airlines deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/265:00 amMDT - ECP
1 stop6h 37mAmerican Airlines
Fri 1/27:15 amECP - MDT
1 stop6h 42mAmerican Airlines
Deal found 12/6$1,193

Find flight deals from Harrisburg to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 8, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$249
(American Airlines)

Popular in

November

Cheapest in

December

Average price

$271
Provider with most accurate pricing for Harrisburg-Panama City NW Florida Beaches flight deals.
Search Deals
Provider most trusted by Cheapflights users for Harrisburg-Panama City NW Florida Beaches flights.
Search Deals
From Harrisburg to Panama City NW Florida Beaches
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($49 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($24 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 8, 2025.
Use the filters below to find and compare flights from Harrisburg to Panama City that are best for you.

Fly from

Harrisburg

Fly to

Panama City

Route

Depart

Return

Price

HarrisburgPanama City

MDT - ECP

MDTECP

Harrisburg

Fri 1/9

12:53 pm-5:33 pm

1 stop5h 40m

Panama City NW Florida Beaches

Mon 1/12

6:03 pm-11:37 pm

1 stop4h 34m

$249

HarrisburgPanama City

MDT - ECP

MDTECP

Harrisburg

Wed 3/18

6:20 pm-11:02 pm

1 stop5h 42m

Panama City NW Florida Beaches

Sun 3/22

6:45 pm-11:47 pm

1 stop4h 02m

$294

HarrisburgPanama City

MDT - ECP

MDTECP

Harrisburg

Sat 5/16

6:43 am-9:24 am

1 stop3h 41m

Panama City NW Florida Beaches

Sat 5/23

2:26 pm-7:45 pm

1 stop4h 19m

$369

HarrisburgPanama City

MDT - ECP

MDTECP

Harrisburg

Sat 1/31

6:30 am-4:12 pm

2 stops10h 42m

Panama City NW Florida Beaches

Tue 2/3

6:30 am-4:34 pm

2 stops9h 04m

$374

HarrisburgPanama City

MDT - ECP

MDTECP

Harrisburg

Sun 4/5

6:15 am-1:09 pm

1 stop7h 54m

Panama City NW Florida Beaches

Sat 4/11

6:40 am-9:18 pm

2 stops13h 38m

$378

HarrisburgPanama City

MDT - ECP

MDTECP

Harrisburg

Sun 4/5

7:51 pm-11:49 pm

1 stop4h 58m

Panama City NW Florida Beaches

Sat 4/11

5:00 pm-11:50 pm

1 stop5h 50m

$443

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/7

Compare providers for flights from Harrisburg to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Harrisburg to Panama City in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Harrisburg-Panama City, Florida flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Harrisburg-Panama City, Florida flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Harrisburg-Panama City, Florida flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Harrisburg-Panama City, Florida flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harrisburg-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Harrisburg to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Panama City

What is the cheapest month to book a flight from Harrisburg to Panama City, Florida?

Currently, November is the cheapest month in which you can book a flight from Harrisburg to Panama City, Florida (average of $107). Flying from Harrisburg to Panama City, Florida in December is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDT to ECP?

Find hourly flight availability from Harrisburg to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 8, 2025.

A simple way to save on the total cost of your ticket is to fly from Harrisburg to Panama City, Florida in the evening. If you’re flexible enough to do this you can expect to save up to 46% on your trip compared to booking a flight at noon.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated December 8, 2025.
See what other customers who have flown with Delta and American Airlines from Harrisburg to Panama City have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,013 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.1

Crew

8.5

Food

7.3

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Delta
7.9
Good
8,013 reviews
Delta
7.9
Good
8,013 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.1

Crew

8.5

Food

7.3

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
American Airlines
7.2
Good
11,042 reviews
Delta
7.9
Good
8,013 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.1

Crew

8.5

Food

7.3

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Harrisburg to Panama City, Florida?

    A quick flight from Harrisburg to Panama City, Florida can take about 5h 40m. American Airlines provides one of the quickest options available for as low as $249. There are 848 mi between Harrisburg and Panama City, Florida. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Harrisburg to Panama City, Florida round-trip?

    Cheapflights users have booked flights from Harrisburg to Panama City, Florida round-trip from $248. Another airline that can offer you cheap pricing is Delta. American Airlines is 37% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Harrisburg to Panama City that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Panama City.

  • Can I find deals for business class flights from Harrisburg to Panama City?

    Yes. Cheapflights offers flight deals from Harrisburg to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to Panama City, Florida?

    Currently, November is the cheapest month in which you can book a flight from Harrisburg to Panama City, Florida (average of $107). Flying from Harrisburg to Panama City, Florida in December is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

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Top 2 airlines flying from Harrisburg to Panama City

Discover the top 2 airlines that operate flights from Harrisburg to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 8, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$407FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$340FlexibilityNo cancel feeOn-timeN/A

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