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Panama City

$249+ Cheap flights from Harrisburg to Panama City, FL (MDT - ECP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/23. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — ECP
Jul 8 — Jul 151
Tue 7/8
Tue 7/15
1 adult, Economy
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Cheapflights Tip: The best prices from Harrisburg to Panama City NW Florida Beaches are usually found in September or October, booked 46 days in advance, depart on a Monday or Tuesday and return on a Wednesday

Cheap flight deals from Harrisburg to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 3, 2025.

Round-trip from

$249
(Delta)

Popular in

February

Cheapest in

September

Average price

$340
From Harrisburg to Panama City NW Florida Beaches
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($36 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2025
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Find flight deals from Harrisburg to Panama City

Cheapest flights from Harrisburg to Panama City
Explore the most affordable flight options available from Harrisburg to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/236:00 amMDT - ECP
1 stop4h 55mDelta
Tue 8/266:00 amECP - MDT
1 stop3h 54mDelta
Deal found 7/2$249
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1210:12 amMDT - ECP
2 stops9h 13mAmerican Airlines
Wed 7/1610:38 amECP - MDT
2 stops8h 40mAmerican Airlines
Deal found 7/2$294
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/86:30 amMDT - ECP
1 stop7h 53mUnited Airlines
Mon 7/142:05 pmECP - MDT
1 stop6h 06mUnited Airlines
Deal found 7/1$379

Cheapflights Fare Finder

Customize your flight search to find flights from Harrisburg to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
Use the filters below to find and compare flights from Harrisburg to Panama City that are best for you.

Fly from

Harrisburg

Fly to

Panama City

Route

Depart

Return

Price

HarrisburgPanama City

MDT - ECP

MDTECP

Harrisburg

Sat 8/23

6:00 am-9:55 am

1 stop4h 55m

Panama City NW Florida Beaches

Tue 8/26

6:00 am-10:54 am

1 stop3h 54m

$249

HarrisburgPanama City

MDT - ECP

MDTECP

Harrisburg

Mon 7/28

5:30 am-12:05 pm

2 stops7h 35m

Panama City NW Florida Beaches

Tue 8/12

6:06 pm-10:57 pm

1 stop3h 51m

$323

HarrisburgPanama City

MDT - ECP

MDTECP

Harrisburg

Sun 9/28

6:15 am-2:11 pm

2 stops8h 56m

Panama City NW Florida Beaches

Sat 10/4

6:30 am-4:52 pm

2 stops9h 22m

$528

HarrisburgPanama City

MDT - ECP

MDTECP

Harrisburg

Sun 7/20

6:25 pm-11:21 pm

1 stop5h 56m

$294

HarrisburgPanama City

MDT - ECP

MDTECP

Harrisburg

Sun 7/20

6:12 am-2:01 pm

2 stops8h 49m

$299

HarrisburgPanama City

MDT - ECP

MDTECP

Harrisburg

Sat 7/12

6:30 am-10:00 pm

3 stops16h 30m

$1,371

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/3

Best time to book a flight from Harrisburg to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Panama City

How far ahead should I book a flight from Harrisburg to Panama City, Florida?

Use this chart to determine the optimal time to book a round-trip flight from Harrisburg to Panama City. Price data was last updated on June 27, 2025.

The price you pay for your flight from Harrisburg to Panama City, Florida may vary depending on when you book. For the best chance of a lower fare, look to book 46 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Harrisburg to Panama City, Florida?

Currently, January is the cheapest month in which you can book a flight from Harrisburg to Panama City, Florida (average of $346). Flying from Harrisburg to Panama City, Florida in March is currently the most expensive (average of $461). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDT to ECP?

Find hourly flight availability from Harrisburg to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 3, 2025.

A simple way to save on the total cost of your ticket is to fly from Harrisburg to Panama City, Florida in the afternoon. If you’re flexible enough to do this you can expect to save up to 32% on your trip compared to booking a flight at noon.

How much does it cost to fly round-trip from Harrisburg to Panama City, Florida?

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated July 3, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Harrisburg to Panama City have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,970 reviews

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Delta
8.0
Very good
7,970 reviews
Delta
8.0
Very good
7,970 reviews

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
United Airlines
7.4
Good
8,845 reviews
Delta
8.0
Very good
7,970 reviews

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,970 reviews

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Harrisburg to Panama City, Florida round-trip?

    Cheapflights users have booked flights from Harrisburg to Panama City, Florida round-trip from $249. Other airlines that can offer you cheap pricing are American Airlines, from $323, and United Airlines, from $528. Delta is 33% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Harrisburg to Panama City, Florida one-way?

    One-way options have recently been found by users for as low as $294 on Delta. Other airlines that offer cheap prices include American Airlines from $299 and United Airlines from $1,371 one-way.

  • Can I find deals for flights from Harrisburg to Panama City that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Panama City.

  • Can I find deals for business class flights from Harrisburg to Panama City?

    Yes. Cheapflights offers flight deals from Harrisburg to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to Panama City, Florida?

    Currently, January is the cheapest month in which you can book a flight from Harrisburg to Panama City, Florida (average of $346). Flying from Harrisburg to Panama City, Florida in March is currently the most expensive (average of $461). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Harrisburg?

Book flights to Harrisburg if you plan to visit one of these locations
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Top 2 airlines flying from Harrisburg to Panama City

Discover the top 2 airlines that operate flights from Harrisburg to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$208Average$353FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$345FlexibilityNo cancel feeOn-time71%

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