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Panama City

$189+ Cheap flights from Greenville to Panama City, FL (GSP - ECP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/4. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — ECP
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Greenville to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$189
(Delta)

Popular in

December

Cheapest in

June

Average price

$386
From Greenville to Panama City NW Florida Beaches
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($62 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease ($27 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
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Find flight deals from Greenville to Panama City

Cheapest flights from Greenville to Panama City
Explore the most affordable flight options available from Greenville to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/45:30 amGSP - ECP
1 stop3h 38mDelta
Tue 10/76:00 amECP - GSP
1 stop5h 47mDelta
Deal found 9/10$189
This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/117:40 amGSP - ECP
2 stops12h 25mSouthwest
Tue 11/187:15 amECP - GSP
1 stop7h 50mSouthwest
Deal found 9/11$267
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/265:30 amGSP - ECP
1 stop3h 38mDelta
Tue 9/309:13 amECP - GSP
1 stop3h 15mDelta
Deal found 9/11$300
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/18:05 amGSP - ECP
1 stop4h 26mAmerican Airlines
Sat 10/42:52 pmECP - GSP
2 stops17h 05mAmerican Airlines
Deal found 9/10$410
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/265:30 amGSP - ECP
1 stop3h 38mDelta
Mon 9/296:54 pmECP - GSP
1 stop3h 58mDelta
Deal found 9/11$411
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/25:30 amGSP - ECP
1 stop3h 38mDelta
Sun 10/56:00 amECP - GSP
1 stop4h 04mDelta
Deal found 9/11$425
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/47:00 amGSP - ECP
1 stop15h 48mUnited Airlines
Tue 10/71:55 pmECP - GSP
2 stops23h 16mUnited Airlines
Deal found 9/9$446
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/135:30 amGSP - ECP
1 stop3h 38mDelta
Wed 9/176:00 amECP - GSP
1 stop4h 24mDelta
Deal found 9/10$471
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/45:41 pmGSP - ECP
2 stops17h 01mAmerican Airlines
Tue 10/711:58 amECP - GSP
2 stops10h 23mAmerican Airlines
Deal found 9/11$486

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Greenville to Panama City that are best for you.

Fly from

Greenville

Fly to

Panama City

Route

Depart

Return

Price

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Sat 10/4

5:30 am-8:08 am

1 stop3h 38m

Panama City NW Florida Beaches

Tue 10/7

6:00 am-12:47 pm

1 stop5h 47m

$189

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Wed 10/1

6:13 pm-11:03 pm

1 stop5h 50m

Panama City NW Florida Beaches

Sat 10/4

5:02 pm-9:07 pm

1 stop3h 05m

$189

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Sat 2/21

7:55 pm-10:42 pm

1 stop3h 47m

Panama City NW Florida Beaches

Thu 2/26

6:00 am-11:00 am

1 stop4h 00m

$226

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Tue 11/11

7:40 am-7:05 pm

2 stops12h 25m

Panama City NW Florida Beaches

Tue 11/18

7:15 am-4:05 pm

1 stop7h 50m

$267

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Sat 2/21

10:35 am-4:00 pm

1 stop6h 25m

Panama City NW Florida Beaches

Thu 2/26

5:50 pm-10:10 am

2 stops15h 20m

$306

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Fri 2/13

3:00 pm-7:38 pm

1 stop5h 38m

Panama City NW Florida Beaches

Mon 2/16

7:05 pm-11:36 pm

1 stop3h 31m

$342

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Wed 10/1

8:05 am-11:31 am

1 stop4h 26m

Panama City NW Florida Beaches

Sat 10/4

2:52 pm-8:57 am

2 stops17h 05m

$410

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Fri 9/19

6:35 am-9:55 am

1 stop4h 20m

$264

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Fri 9/19

12:34 pm-4:20 pm

2 stops28h 46m

$490

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Best time to book a flight from Greenville to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Panama City

What is the cheapest month to book a flight from Greenville to Panama City, Florida?

Currently, January is the cheapest month in which you can book a flight from Greenville to Panama City, Florida (average of $346). Flying from Greenville to Panama City, Florida in March is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GSP to ECP?

Find hourly flight availability from Greenville to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

It’s typically best to fly out from Greenville to Panama City, Florida in the evening. Doing so could potentially save you 22% on the flight price compared to flying in the morning, which is usually more expensive.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 11, 2025.
Peruse reviews from past customers who have flown with Southwest and Delta from Greenville to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,248 reviews

Comfort

8.0

Entertainment

7.5

Overall

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,248 reviews
Southwest
8.0
Very good
4,248 reviews

Comfort

8.0

Entertainment

7.5

Overall

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,960 reviews
Southwest
8.0
Very good
4,248 reviews

Comfort

8.0

Entertainment

7.5

Overall

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Greenville to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Greenville to Panama City, Florida?

    There are many flights that can get you from Greenville to Panama City, Florida in 3h 38m. Fly via Delta to get the fastest option. Greenville and Panama City, Florida are separated by a distance of 376 mi.

  • What are the cheapest airlines flying from Greenville to Panama City, Florida round-trip?

    Our cheapest airline available from Greenville to Panama City, Florida is Delta. Our recent data shows that you can find tickets from as low as $256 on this airline. An additional option worth looking into is Southwest, starting at $301. Delta is currently priced 31% below the average price you’ll pay for this route.

  • Can I find deals for flights from Greenville to Panama City that include hotel bookings?

    Yes. In addition to deals on Greenville to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Panama City.

  • Can I find deals for business class flights from Greenville to Panama City?

    Yes. Cheapflights offers flight deals from Greenville to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Panama City, Florida?

    Currently, January is the cheapest month in which you can book a flight from Greenville to Panama City, Florida (average of $346). Flying from Greenville to Panama City, Florida in March is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

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Top 2 airlines flying from Greenville to Panama City

Discover the top 2 airlines that operate flights from Greenville to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$256Average$350FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$301Average$361FlexibilityNo cancel feeOn-time63%

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