What are the cheapest airlines flying from Greenville to Panama City, Florida round-trip?

Our cheapest airline available from Greenville to Panama City, Florida is Delta. Our recent data shows that you can find tickets from as low as $252 on this airline. Additional options worth looking into are American Airlines and Southwest, starting at $272 and $308 round-trip. Delta is currently priced 31% below the average price you’ll pay for this route.

What are the cheapest airlines to fly from Greenville to Panama City, Florida one-way?

For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $99. Users have also found prices from $104 and $144 on Southwest and Delta, respectively.

What is the cheapest day to fly from Greenville to Panama City, Florida?

Travelers seeking maximum savings on their Greenville to Panama City, Florida flight should consider departing on Tuesday mornings when fares are most often at their lowest. Thursday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Panama City, Florida ranges from 2.8 - 7.9 inches per month. July is typically the wettest month, when rainfall can reach 7.9 in. May is typically the driest time to visit Panama City, Florida when rainfall is around 2.8 in.

If weather is an important factor for your trip to Panama City, Florida, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 53.6 F).

What are the most popular airlines that fly from Greenville to Panama City, Florida?

The most popular airlines flying from Greenville to Panama City, Florida are American Airlines, Delta and Southwest. Something to consider prior to booking your flight.

What is the cheapest day to fly round-trip from Greenville to Panama City, Florida?

Flying to your destination on a Tuesday can be more expensive, but this shouldn’t discourage you from finding affordable options to get to Panama City, Florida. Check prices with Cheapflights to find a great deal for your trip.

What is the cheapest month to fly from Greenville to Panama City, Florida?

Our data shows that June tends to be the cheapest month to fly to Panama City, Florida from Greenville. Users have commonly found prices around $370 for the month, but tickets can be as low as $158. Due to multiple factors, prepare for potentially higher prices in December.

Can I find deals for flights from Greenville to Panama City that include hotel bookings?

Yes. In addition to deals on Greenville to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Greenville to Panama City?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Panama City.

Can I find deals for business class flights from Greenville to Panama City?

Yes. Cheapflights offers flight deals from Greenville to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$144+ Flights from Greenville to Panama City, FL

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Cheap flight deals from Greenville to Panama City

Round-trip from	$252 (Delta)
One-way from	$99 (American Airlines)
Popular in	December
Cheapest in	June
Average price	$365

From Greenville to Panama City NW Florida Beaches

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One-way flight from Greenville to Panama City NW Florida Beaches

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Highest demand for flights based on searches. 12% potential increase in price ($52 potential increase over avg. RT price).

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Cheapest flight prices on average. 7% potential price decrease ($27 potential savings vs. average RT price).

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Average for round-trip flights in July 2025

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Find flight deals from Greenville to Panama City

Cheapest flights from Greenville to Panama City
Explore the most affordable flight options available from Greenville to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.

Wed 10/225:30 amGSP - ECP

1 stop4h 14mDelta

Mon 10/276:17 pmECP - GSP

1 stop4h 37mDelta

Deal found 7/30

$242

Sun 8/177:15 pmGSP - ECP

1 stop5h 26mAmerican Airlines

Sat 8/237:06 pmECP - GSP

1 stop3h 51mAmerican Airlines

Deal found 7/30

$294

Mon 8/117:40 amGSP - ECP

2 stops14h 20mSouthwest

Thu 8/141:30 pmECP - GSP

1 stop3h 35mSouthwest

Deal found 7/28

$415

Thu 9/47:00 amGSP - ECP

1 stop14h 16mUnited Airlines

Sun 9/75:06 pmECP - GSP

2 stops20h 10mUnited Airlines

Deal found 7/28

$680

Best flights from Greenville to Panama City
Discover carefully curated flight deals from Greenville to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 30, 2025.

Wed 10/225:30 amGSP - ECP

1 stop4h 14mDelta

Mon 10/276:17 pmECP - GSP

1 stop4h 37mDelta

Deal found 7/30

$242

Sun 8/177:15 pmGSP - ECP

1 stop5h 26mAmerican Airlines

Sat 8/237:06 pmECP - GSP

1 stop3h 51mAmerican Airlines

Deal found 7/30

$294

Mon 8/117:40 amGSP - ECP

2 stops14h 20mSouthwest

Thu 8/141:30 pmECP - GSP

1 stop3h 35mSouthwest

Deal found 7/28

$415

Thu 9/47:00 amGSP - ECP

1 stop14h 16mUnited Airlines

Sun 9/75:06 pmECP - GSP

2 stops20h 10mUnited Airlines

Deal found 7/28

$680

Last-minute flights from Greenville to Panama City
Discover last-minute flight deals from Greenville to Panama City. Data last updated July 30, 2025 and is based on user searches.

Mon 8/117:40 amGSP - ECP

2 stops14h 20mSouthwest

Thu 8/141:30 pmECP - GSP

1 stop3h 35mSouthwest

Deal found 7/28

$415

Thu 8/147:45 pmGSP - ECP

2 stops18h 38mUnited Airlines

Mon 8/185:02 pmECP - GSP

2 stops20h 14mUnited Airlines

Deal found 7/30

$798

Sun 8/177:15 pmGSP - ECP

1 stop5h 26mAmerican Airlines

Sat 8/237:06 pmECP - GSP

1 stop3h 51mAmerican Airlines

Deal found 7/30

$294

Thu 8/215:30 amGSP - ECP

1 stop3h 49mDelta

Mon 8/256:54 pmECP - GSP

1 stop3h 40mDelta

Deal found 7/30

$267

One-way flights from Greenville to Panama City
Search for one-way flight options from Greenville to Panama City. Find affordable one-way fares based on user searches. Data last updated July 30, 2025.

Fri 9/55:30 amGSP - ECP

1 stop3h 42mDelta

Deal found 7/30

$144

Mon 9/87:40 amGSP - ECP

2 stops10h 15mSouthwest

Deal found 7/29

$189

Mon 9/85:52 pmGSP - ECP

3 stops20h 11mUnited Airlines

Deal found 7/29

$384

Cheapflights Fare Finder

Use the filters below to find and compare flights from Greenville to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Wed 10/22

5:30 am-8:44 am

1 stop4h 14m

Panama City NW Florida Beaches

Mon 10/27

6:17 pm-11:54 pm

1 stop4h 37m

$242

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Sun 8/17

7:15 pm-11:41 pm

1 stop5h 26m

Panama City NW Florida Beaches

Sat 8/23

7:06 pm-11:57 pm

1 stop3h 51m

$294

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Mon 8/11

7:40 am-9:00 pm

2 stops14h 20m

Panama City NW Florida Beaches

Thu 8/14

1:30 pm-6:05 pm

1 stop3h 35m

$415

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Thu 9/4

7:00 am-8:16 pm

1 stop14h 16m

Panama City NW Florida Beaches

Sun 9/7

5:06 pm-2:16 pm

2 stops20h 10m

$680

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Fri 9/5

5:30 am-8:12 am

1 stop3h 42m

$144

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Mon 9/8

7:40 am-4:55 pm

2 stops10h 15m

$189

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Mon 9/8

5:52 pm-1:03 pm

3 stops20h 11m

$384

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Best time to book a flight from Greenville to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Greenville with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Panama City

What is the cheapest month to book a flight from Greenville to Panama City, Florida?

Currently, January is the cheapest month in which you can book a flight from Greenville to Panama City, Florida (average of $346). Flying from Greenville to Panama City, Florida in March is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GSP to ECP?

It’s typically best to fly out from Greenville to Panama City, Florida in the evening. Doing so could potentially save you 22% on the flight price compared to flying in the morning, which is usually more expensive.

Reviews of airlines servicing Panama City

Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Greenville to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,241 reviews

Reviews

1 / 20

8.0

Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Southwest

8.0

Very good

4,241 reviews

Southwest

8.0

Very good

4,241 reviews

Reviews

1 / 20

8.0

Excellent

Gina,Jul 2025

LAS - DEN

Delta

8.0

Very good

7,980 reviews

Southwest

8.0

Very good

4,241 reviews

Reviews

1 / 20

8.0

Excellent

Gina,Jul 2025

LAS - DEN

United Airlines

7.4

Good

8,896 reviews

Southwest

8.0

Very good

4,241 reviews

Reviews

1 / 20

8.0

Excellent

Gina,Jul 2025

LAS - DEN

American Airlines

7.2

Good

10,000 reviews

Southwest

8.0

Very good

4,241 reviews

Reviews

1 / 20

8.0

Excellent

Gina,Jul 2025

LAS - DEN

Related info for your journey

What are the cheapest airlines flying from Greenville to Panama City, Florida round-trip?
Our cheapest airline available from Greenville to Panama City, Florida is Delta. Our recent data shows that you can find tickets from as low as $252 on this airline. Additional options worth looking into are American Airlines and Southwest, starting at $272 and $308 round-trip. Delta is currently priced 31% below the average price you’ll pay for this route.
What are the cheapest airlines to fly from Greenville to Panama City, Florida one-way?
For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $99. Users have also found prices from $104 and $144 on Southwest and Delta, respectively.
Can I find deals for flights from Greenville to Panama City that include hotel bookings?
Yes. In addition to deals on Greenville to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Greenville to Panama City?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Panama City.
Can I find deals for business class flights from Greenville to Panama City?
Yes. Cheapflights offers flight deals from Greenville to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Greenville to Panama City, Florida?
Currently, January is the cheapest month in which you can book a flight from Greenville to Panama City, Florida (average of $346). Flying from Greenville to Panama City, Florida in March is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Mexico Beach

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Top 3 airlines flying from Greenville to Panama City

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$252	Average$346	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$256	Average$367	FlexibilityNo cancel fee	On-time71%
Southwest	Cheapest$301	Average$356	FlexibilityNo cancel fee	On-time63%

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$144+ Cheap flights from Greenville to Panama City, FL (GSP - ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/5. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Greenville to Panama City with Cheapflights

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2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Greenville to Panama City

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Greenville to Panama City

Cheapest flights from Greenville to Panama CityExplore the most affordable flight options available from Greenville to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.

Explore the most affordable flight options available from Greenville to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Greenville to Panama City that are best for you.

Best time to book a flight from Greenville to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Greenville with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Panama City

What is the cheapest month to book a flight from Greenville to Panama City, Florida?

What is the cheapest time of day to fly from GSP to ECP?

Find hourly flight availability from Greenville to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 30, 2025.

Reviews of airlines servicing Panama City

Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Greenville to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Greenville to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Greenville to Panama City, Florida round-trip?

What are the cheapest airlines to fly from Greenville to Panama City, Florida one-way?

Can I find deals for flights from Greenville to Panama City that include hotel bookings?

How can I find direct flights from Greenville to Panama City?

Can I find deals for business class flights from Greenville to Panama City?

What is the cheapest month to book a flight from Greenville to Panama City, Florida?

Traveling to a place near Panama City?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Greenville to Panama City

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Greenville to Panama City

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Cheapest flights from Greenville to Panama City
Explore the most affordable flight options available from Greenville to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.