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Panama City

$153+ Cheap flights from Greenville to Panama City, FL (GSP - ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/28. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — ECP
Apr 17 — Apr 241
Fri 4/17
Fri 4/24
1 adult, Economy
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Cheap flight deals from Greenville to Panama City

Cheapest flights from Greenville to Panama City
Explore the most affordable flight options available from Greenville to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 18, 2026.

This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/210:09 am
GSP
-
ECP
1 stop3h 41m
Delta
Tue 6/97:45 am
ECP
-
GSP
1 stop4h 23m
Delta
Deal found 3/17$287
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:42 pm
GSP
-
ECP
1 stop4h 46m
Delta
Wed 6/107:45 am
ECP
-
GSP
1 stop6h 07m
Delta
Deal found 3/17$297
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:42 pm
GSP
-
ECP
1 stop4h 46m
Delta
Thu 6/47:41 am
ECP
-
GSP
1 stop3h 27m
Delta
Deal found 3/17$307
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:45 am
GSP
-
ECP
1 stop5h 05m
Delta
Sat 6/67:41 am
ECP
-
GSP
1 stop5h 33m
Delta
Deal found 3/17$317
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:42 pm
GSP
-
ECP
1 stop4h 46m
Delta
Sat 6/67:41 am
ECP
-
GSP
1 stop3h 24m
Delta
Deal found 3/17$327
This Southwest deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/812:35 pm
GSP
-
ECP
2 stops10h 05m
Southwest
Mon 5/116:40 am
ECP
-
GSP
2 stops10h 10m
Southwest
Deal found 3/17$337
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:45 am
GSP
-
ECP
1 stop5h 28m
Delta
Mon 9/219:23 am
ECP
-
GSP
1 stop4h 29m
Delta
Deal found 3/17$347
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/47:42 pm
GSP
-
ECP
1 stop4h 46m
Delta
Tue 6/96:00 am
ECP
-
GSP
1 stop4h 00m
Delta
Deal found 3/17$353
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/47:42 pm
GSP
-
ECP
1 stop4h 46m
Delta
Mon 6/87:45 am
ECP
-
GSP
1 stop6h 07m
Delta
Deal found 3/17$363
This Southwest deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/112:35 pm
GSP
-
ECP
2 stops10h 05m
Southwest
Fri 5/811:30 am
ECP
-
GSP
2 stops9h 45m
Southwest
Deal found 3/17$367
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/611:36 am
GSP
-
ECP
1 stop6h 01m
Delta
Wed 6/107:45 am
ECP
-
GSP
1 stop6h 07m
Delta
Deal found 3/17$373

Find flight deals from Greenville to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 18, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$287
(Delta)

One-way from

$153
(American Airlines)

Popular in

October

Cheapest in

December

Average price

$311
Provider with most accurate pricing for Greenville-Panama City NW Florida Beaches flight deals.
Search Deals
Provider most trusted by Cheapflights users for Greenville-Panama City NW Florida Beaches flights.
Search Deals
From Greenville to Panama City NW Florida Beaches
Search Deals
One-way flight from Greenville to Panama City NW Florida Beaches
Search Deals
Highest demand for flights based on searches. 30% potential increase in price ($173 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 9% potential price decrease ($34 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 18, 2026.
Use the filters below to find and compare flights from Greenville to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Wed 6/3

8:45 am-10:49 am

1 stop3h 04m

Panama City NW Florida Beaches

Thu 6/4

1:50 pm-8:13 pm

1 stop5h 23m

$297
Quickest round-trip

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Sun 6/7

5:45 am-8:17 am

1 stop3h 32m

Panama City NW Florida Beaches

Tue 6/9

6:00 am-11:00 am

1 stop4h 00m

$317

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Fri 5/8

12:35 pm-9:40 pm

2 stops10h 05m

Panama City NW Florida Beaches

Mon 5/11

6:40 am-5:50 pm

2 stops10h 10m

$337

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Fri 6/5

8:45 am-12:50 pm

1 stop5h 05m

Panama City NW Florida Beaches

Fri 6/5

6:45 pm-11:43 pm

1 stop3h 58m

$347

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Mon 8/3

7:05 am-2:15 pm

2 stops8h 10m

Panama City NW Florida Beaches

Sun 8/9

12:50 pm-8:30 pm

1 stop6h 40m

$382

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Tue 5/19

6:36 am-1:17 pm

1 stop7h 41m

Panama City NW Florida Beaches

Wed 5/20

2:14 pm-10:58 pm

1 stop7h 44m

$443

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Thu 4/2

12:25 pm-8:35 pm

1 stop9h 10m

Panama City NW Florida Beaches

Fri 4/3

6:15 am-5:45 pm

2 stops10h 30m

$459

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Tue 3/31

12:35 pm-8:00 pm

2 stops8h 25m

Panama City NW Florida Beaches

Sat 4/4

1:45 pm-10:45 pm

2 stops8h 00m

$469
Cheapest one-way

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Tue 4/28

5:48 pm-10:52 pm

1 stop6h 04m

$153

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Wed 4/15

5:20 am-10:03 am

1 stop5h 43m

$154

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/14

Showing 1-10 of 16 resultsSorted by cheapest first
1
2

Compare providers for flights from Greenville to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to Panama City in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Greenville-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville-Panama City, Florida flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Greenville-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Greenville to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Panama City

What is the cheapest month to book a flight from Greenville to Panama City, Florida?

Currently, September is the cheapest month in which you can book a flight from Greenville to Panama City, Florida (average of $124). Flying from Greenville to Panama City, Florida in December is currently the most expensive (average of $278). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated March 18, 2026.
Peruse reviews from past customers who have flown with Delta from Greenville to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,286 reviews

Crew

8.5

Comfort

7.9

Overall

7.9

Boarding

8.1

Food

7.2

Entertainment

7.8

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
8,286 reviews
Delta
7.9
Good
8,286 reviews

Crew

8.5

Comfort

7.9

Overall

7.9

Boarding

8.1

Food

7.2

Entertainment

7.8

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Greenville to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Greenville to Panama City, Florida?

    There are many flights that can get you from Greenville to Panama City, Florida in 4h 46m. Fly via Delta or Southwest to get the fastest option. Greenville and Panama City, Florida are separated by a distance of 376 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Greenville to Panama City, Florida round-trip?

    Our cheapest airline available from Greenville to Panama City, Florida is Delta. Our recent data shows that you can find tickets from as low as $266 on this airline. Delta is currently priced 32% below the average price you’ll pay for this route.

  • Can I find deals for flights from Greenville to Panama City that include hotel bookings?

    Yes. In addition to deals on Greenville to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Panama City.

  • Can I find deals for business class flights from Greenville to Panama City?

    Yes. Cheapflights offers flight deals from Greenville to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Panama City, Florida?

    Currently, September is the cheapest month in which you can book a flight from Greenville to Panama City, Florida (average of $124). Flying from Greenville to Panama City, Florida in December is currently the most expensive (average of $278). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

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Top airline flying from Greenville to Panama City

Discover the top airline that operate flights from Greenville to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 18, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$266Average$381FlexibilityNo cancel feeOn-timeN/A

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