HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama City

$580+ Cheap flights from the Dominican Republic to Panama City, FL (ECP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/22. Fares are subject to change and may not be available on all flights or dates of travel.
PUJ — ECP
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Dominican Republic to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Dominican Republic to Panama City

Keep the following information in mind while searching for Dominican Republic to Panama City flight deals. Data was last updated September 15, 2025.

Round-trip from

$580
(American Airlines)
From Dominican Republic to Panama City NW Florida Beaches
Search Deals

Find flight deals from Dominican Republic to Panama City

Cheapest flights from Dominican Republic to Panama City
Explore the most affordable flight options available from Dominican Republic to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/226:17 pmSTI - ECP
2 stops17h 39mAmerican Airlines
Wed 1/76:48 amECP - STI
2 stops12h 36mAmerican Airlines
Deal found 9/14$580
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/271:29 pmSTI - ECP
2 stops21h 13mAmerican Airlines
Fri 10/101:47 pmECP - STI
2 stops21h 26mAmerican Airlines
Deal found 9/13$719
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/213:30 amSTI - ECP
2 stops18h 27mDelta
Wed 1/75:10 pmECP - STI
2 stops17h 58mDelta
Deal found 9/14$1,275

Cheapflights Fare Finder

 
Customize your flight search to find flights from Dominican Republic to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from the Dominican Republic to Panama City that are best for you.

Fly from

Dominican Republic

Fly to

Panama City

Route

Depart

Return

Price

Santiago de los CaballerosPanama City

STI - ECP

STIECP

Santiago de los Caballeros

Mon 12/22

6:17 pm-9:56 am

2 stops17h 39m

Panama City NW Florida Beaches

Wed 1/7

6:48 am-9:24 pm

2 stops12h 36m

$580

Santiago de los CaballerosPanama City

STI - ECP

STIECP

Santiago de los Caballeros

Sat 9/27

1:29 pm-9:42 am

2 stops21h 13m

Panama City NW Florida Beaches

Fri 10/10

1:47 pm-12:13 pm

2 stops21h 26m

$719

Santiago de los CaballerosPanama City

STI - ECP

STIECP

Santiago de los Caballeros

Sun 12/21

3:30 am-7:57 pm

2 stops18h 27m

Panama City NW Florida Beaches

Wed 1/7

5:10 pm-1:08 pm

2 stops17h 58m

$1,275

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Best time to book a flight from Dominican Republic to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Dominican Republic with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from the Dominican Republic to Panama City
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Dominican Republic to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Dominican Republic?

    Most people fly into Panama City NW Florida Beaches (ECP) if they book a flight to Panama City from Dominican Republic. NW Florida Beaches is conveniently located just 16.0 mi from Panama City’s city center.

  • How long is the flight from Dominican Republic to Panama City, Florida?

    For as low as $580, American Airlines can have you in Panama City, Florida from Dominican Republic in 17h 39m. There are 1213 mi between Dominican Republic and Panama City, Florida. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Dominican Republic to Panama City that include hotel bookings?

    Yes. In addition to deals on Dominican Republic to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Dominican Republic to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Dominican Republic to Panama City.

  • Can I find deals for business class flights from Dominican Republic to Panama City?

    Yes. Cheapflights offers flight deals from Dominican Republic to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Dominican Republic to Panama City, Florida?

    Currently, January is the cheapest month in which you can book a flight from Dominican Republic to Panama City, Florida (average of $346). Flying from Dominican Republic to Panama City, Florida in March is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Dominican Republic to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
Luis Munoz Marin Intl to Orlando flights
Luis Munoz Marin Intl to Fort Lauderdale flights
Luis Munoz Marin Intl to Miami flights
Luis Munoz Marin Intl to Tampa flights
Ponce to Orlando flights
Santo Domingo to Orlando flights
Aguadilla to Orlando flights
Port of Spain to Miami flights
Santo Domingo to Miami flights
Luis Munoz Marin Intl to Jacksonville flights
Nassau to Miami flights
Pointe-à-Pitre to Miami flights
Santo Domingo to Fort Lauderdale flights
Nassau to Fort Lauderdale flights
Kingston to Fort Lauderdale flights
Oranjestad to Miami flights
Bridgetown to Miami flights
Kingston to Miami flights
Nassau to Orlando flights
Santiago de los Caballeros to Orlando flights
Port of Spain to Fort Lauderdale flights
Willemstad to Miami flights
Oranjestad to Orlando flights
Montego Bay to Orlando flights
Aguadilla to Fort Lauderdale flights
Fort-de-France to Miami flights
Montego Bay to Fort Lauderdale flights
Port of Spain to Orlando flights
Saint Thomas Island to Fort Lauderdale flights
Simpson Bay to Miami flights
Saint Thomas Island to Miami flights
Santiago de los Caballeros to Fort Lauderdale flights
Punta Cana to Orlando flights
Santiago de los Caballeros to Miami flights
Luis Munoz Marin Intl to West Palm Beach flights
George Town to Miami flights
Kingston to Orlando flights
Montego Bay to Miami flights
Saint Thomas Island to Tampa flights
Luis Munoz Marin Intl to Daytona Beach flights
Providenciales to Miami flights
Luis Munoz Marin Intl to Melbourne flights
Santo Domingo to Tampa flights
Simpson Bay to Fort Lauderdale flights
Punta Cana to Miami flights
St. John's to Miami flights
George Town to Orlando flights
Simpson Bay to Orlando flights
Bridgetown to Fort Lauderdale flights
Saint Thomas Island to Orlando flights

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.