$130+ Cheap flights from Detroit Metropolitan Wayne County Airport to Panama City, FL (DTW - ECP)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/12. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — ECP
Apr 10 — Apr 171
Round-trip
1 adult, Economy
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Cheapest flights from Detroit to Panama CityExplore the most affordable flight options available from Detroit to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 11, 2026.
Explore the most affordable flight options available from Detroit to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 11, 2026.
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2910:00 am
DTW
- ECP
Nonstop2h 15m
Delta
Sat 9/512:05 pm
ECP
- DTW
Nonstop2h 32m
Delta
Deal found 3/8![Delta logo]()
$239
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2910:00 am
DTW
- ECP
Nonstop2h 15m
Delta
Thu 9/34:10 pm
ECP
- DTW
1 stop6h 30m
Delta
Deal found 3/8![Delta logo]()
$249
This Southwest deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:15 am
DTW
- ECP
1 stop3h 45m
Southwest
Sat 5/27:20 am
ECP
- DTW
1 stop6h 40m
Southwest
Deal found 3/8![Southwest logo]()
$259
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/107:49 pm
DTW
- ECP
1 stop4h 57m
American Airlines
Tue 4/147:21 am
ECP
- DTW
1 stop7h 14m
American Airlines
Deal found 3/8![American Airlines logo]()
$260
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/187:20 am
DTW
- ECP
2 stops9h 25m
Southwest
Sat 4/259:50 am
ECP
- DTW
2 stops10h 35m
Southwest
Deal found 3/6![Southwest logo]()
$269
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:25 pm
DTW
- ECP
1 stop4h 25m
Southwest
Tue 6/97:00 am
ECP
- DTW
2 stops11h 30m
Southwest
Deal found 3/10![Southwest logo]()
$270
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/131:00 pm
DTW
- ECP
2 stops7h 50m
Southwest
Thu 4/169:55 am
ECP
- DTW
2 stops10h 15m
Southwest
Deal found 3/6![Southwest logo]()
$275
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/2510:00 am
DTW
- ECP
Nonstop2h 15m
Delta
Sat 8/112:05 pm
ECP
- DTW
Nonstop2h 32m
Delta
Deal found 3/6![Delta logo]()
$278
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:20 am
DTW
- ECP
1 stop6h 03m
Delta
Tue 4/145:10 pm
ECP
- DTW
1 stop6h 34m
Delta
Deal found 3/9![Delta logo]()
$279
This Southwest deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/56:00 am
DTW
- ECP
2 stops9h 15m
Southwest
Wed 4/81:55 pm
ECP
- DTW
1 stop6h 20m
Southwest
Deal found 3/8![Southwest logo]()
$284
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/2510:00 am
DTW
- ECP
Nonstop2h 15m
Delta
Thu 7/301:30 pm
ECP
- DTW
1 stop6h 49m
Delta
Deal found 3/6![Delta logo]()
$288
Best flights from Detroit to Panama CityDiscover carefully curated flight deals from Detroit to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 11, 2026.
Discover carefully curated flight deals from Detroit to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 11, 2026.
This Southwest deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/253:40 pm
DTW
- ECP
1 stop4h 20m
Southwest
Sat 5/29:55 am
ECP
- DTW
2 stops10h 30m
Southwest
Deal found 3/8![Southwest logo]()
$264
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:20 am
DTW
- ECP
1 stop4h 20m
Delta
Mon 3/306:43 pm
ECP
- DTW
1 stop5h 00m
Delta
Deal found 3/8![Delta logo]()
$329
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2310:28 am
DTW
- ECP
2 stops12h 29m
United Airlines
Thu 3/265:03 pm
ECP
- DTW
1 stop5h 56m
United Airlines
Deal found 3/6![United Airlines logo]()
$364
This Southwest deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/14:15 pm
DTW
- ECP
1 stop4h 20m
Southwest
Wed 4/227:15 am
ECP
- DTW
1 stop4h 25m
Southwest
Deal found 3/7![Southwest logo]()
$318
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:20 am
DTW
- ECP
1 stop4h 20m
Delta
Tue 3/316:00 am
ECP
- DTW
1 stop6h 02m
Delta
Deal found 3/8![Delta logo]()
$329
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/247:31 am
DTW
- ECP
1 stop6h 43m
United Airlines
Fri 3/275:03 pm
ECP
- DTW
1 stop5h 56m
United Airlines
Deal found 3/9![United Airlines logo]()
$379
This Southwest deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/56:00 am
DTW
- ECP
2 stops9h 15m
Southwest
Wed 4/812:05 pm
ECP
- DTW
2 stops9h 25m
Southwest
Deal found 3/8![Southwest logo]()
$353
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/56:00 am
DTW
- ECP
2 stops9h 15m
Southwest
Sun 4/126:05 pm
ECP
- DTW
1 stop4h 00m
Southwest
Deal found 3/6![Southwest logo]()
$354
This Southwest deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/214:45 pm
DTW
- ECP
1 stop4h 40m
Southwest
Tue 3/247:00 am
ECP
- DTW
2 stops9h 30m
Southwest
Deal found 3/7![Southwest logo]()
$394
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/234:30 pm
DTW
- ECP
1 stop5h 05m
Southwest
Mon 3/301:55 pm
ECP
- DTW
2 stops9h 20m
Southwest
Deal found 3/9![Southwest logo]()
$404
This Southwest deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/112:55 pm
DTW
- ECP
2 stops8h 05m
Southwest
Mon 5/46:40 am
ECP
- DTW
2 stops11h 55m
Southwest
Deal found 3/7![Southwest logo]()
$407
This Southwest deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/204:30 pm
DTW
- ECP
1 stop5h 05m
Southwest
Wed 3/253:05 pm
ECP
- DTW
1 stop4h 30m
Southwest
Deal found 3/8![Southwest logo]()
$414
Last-minute flights from Detroit to Panama CityDiscover last-minute flight deals from Detroit to Panama City. Data last updated March 11, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to Panama City. Data last updated March 11, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/56:00 am
DTW
- ECP
2 stops9h 15m
Southwest
Wed 4/81:55 pm
ECP
- DTW
1 stop6h 20m
Southwest
Deal found 3/8![Southwest logo]()
$284
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:20 am
DTW
- ECP
1 stop6h 03m
Delta
Tue 4/145:10 pm
ECP
- DTW
1 stop6h 34m
Delta
Deal found 3/9![Delta logo]()
$279
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/82:50 pm
DTW
- ECP
2 stops9h 56m
American Airlines
Wed 4/1510:48 am
ECP
- DTW
2 stops10h 28m
American Airlines
Deal found 3/9![American Airlines logo]()
$290
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/84:14 pm
DTW
- ECP
1 stop4h 33m
Delta
Wed 4/155:10 pm
ECP
- DTW
1 stop6h 34m
Delta
Deal found 3/10![Delta logo]()
$299
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/107:49 pm
DTW
- ECP
1 stop4h 57m
American Airlines
Tue 4/147:21 am
ECP
- DTW
1 stop7h 14m
American Airlines
Deal found 3/8![American Airlines logo]()
$260
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/115:20 am
DTW
- ECP
1 stop4h 20m
Delta
Mon 4/136:46 pm
ECP
- DTW
1 stop4h 58m
Delta
Deal found 3/9![Delta logo]()
$298
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/115:05 pm
DTW
- ECP
2 stops7h 41m
American Airlines
Sat 4/187:00 am
ECP
- DTW
1 stop6h 49m
American Airlines
Deal found 3/6![American Airlines logo]()
$303
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/131:00 pm
DTW
- ECP
2 stops7h 50m
Southwest
Thu 4/169:55 am
ECP
- DTW
2 stops10h 15m
Southwest
Deal found 3/6![Southwest logo]()
$275
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/187:20 am
DTW
- ECP
2 stops9h 25m
Southwest
Sat 4/259:50 am
ECP
- DTW
2 stops10h 35m
Southwest
Deal found 3/6![Southwest logo]()
$269
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/187:20 am
DTW
- ECP
2 stops9h 25m
Southwest
Wed 4/2210:10 am
ECP
- DTW
2 stops7h 10m
Southwest
Deal found 3/10![Southwest logo]()
$289
This Southwest deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:15 am
DTW
- ECP
1 stop3h 45m
Southwest
Sat 5/27:20 am
ECP
- DTW
1 stop6h 40m
Southwest
Deal found 3/8![Southwest logo]()
$259
One-way flights from Detroit to Panama CitySearch for one-way flight options from Detroit to Panama City. Find affordable one-way fares based on user searches. Data last updated March 11, 2026.
Search for one-way flight options from Detroit to Panama City. Find affordable one-way fares based on user searches. Data last updated March 11, 2026.
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/125:35 am
DTW
- ECP
1 stop5h 05m
Southwest
Deal found 3/9![Southwest logo]()
$130
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/56:00 am
DTW
- ECP
2 stops9h 15m
Southwest
Deal found 3/6![Southwest logo]()
$135
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/174:47 pm
DTW
- ECP
1 stop6h 12m
United Airlines
Deal found 3/6![United Airlines logo]()
$150
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/62:05 pm
DTW
- ECP
2 stops8h 54m
United Airlines
Deal found 3/6![United Airlines logo]()
$155
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/49:00 am
DTW
- ECP
1 stop5h 18m
United Airlines
Deal found 3/6![United Airlines logo]()
$165
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:20 am
DTW
- ECP
1 stop4h 20m
Delta
Deal found 3/9![Delta logo]()
$169
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/51:41 pm
DTW
- ECP
2 stops9h 24m
United Airlines
Deal found 3/8![United Airlines logo]()
$170
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/127:18 am
DTW
- ECP
1 stop7h 05m
United Airlines
Deal found 3/10![United Airlines logo]()
$175
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/107:17 pm
DTW
- ECP
1 stop4h 47m
Delta
Deal found 3/10![Delta logo]()
$179
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1110:53 am
DTW
- ECP
2 stops12h 06m
United Airlines
Deal found 3/10![United Airlines logo]()
$180
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/57:45 pm
DTW
- ECP
1 stop4h 19m
Delta
Deal found 3/9![Delta logo]()
$189
Find flight deals from Detroit to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $259 (Southwest) |
One-way from | $130 (Southwest) |
Popular in | March |
Cheapest in | September |
Average price | $464 |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 11, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitPanama City
DTW - ECP
DTWECP
Detroit Metropolitan Wayne County
Sat 4/25
3:40 pm-7:00 pm
1 stop4h 20m
Panama City NW Florida Beaches
Sat 5/2
9:55 am-9:25 pm
2 stops10h 30m
$264
Quickest round-trip
DetroitPanama City
DTW - ECP
DTWECP
Detroit Metropolitan Wayne County
Wed 4/1
4:15 pm-7:35 pm
1 stop4h 20m
Panama City NW Florida Beaches
Wed 4/22
7:15 am-12:40 pm
1 stop4h 25m
$318
DetroitPanama City
DTW - ECP
DTWECP
Detroit Metropolitan Wayne County
Tue 3/24
5:20 am-8:40 am
1 stop4h 20m
Panama City NW Florida Beaches
Mon 3/30
6:43 pm-12:43 am
1 stop5h 00m
$329
DetroitPanama City
DTW - ECP
DTWECP
Detroit Metropolitan Wayne County
Tue 3/24
5:20 am-8:40 am
1 stop4h 20m
Panama City NW Florida Beaches
Tue 3/31
6:00 am-1:02 pm
1 stop6h 02m
$329
DetroitPanama City
DTW - ECP
DTWECP
Detroit Metropolitan Wayne County
Sun 4/5
6:00 am-2:15 pm
2 stops9h 15m
Panama City NW Florida Beaches
Wed 4/8
12:05 pm-10:30 pm
2 stops9h 25m
$353
DetroitPanama City
DTW - ECP
DTWECP
Detroit Metropolitan Wayne County
Sun 4/5
6:00 am-2:15 pm
2 stops9h 15m
Panama City NW Florida Beaches
Sun 4/12
6:05 pm-11:05 pm
1 stop4h 00m
$354
DetroitPanama City
DTW - ECP
DTWECP
Detroit Metropolitan Wayne County
Mon 3/23
10:28 am-9:57 pm
2 stops12h 29m
Panama City NW Florida Beaches
Thu 3/26
5:03 pm-11:59 pm
1 stop5h 56m
$364
DetroitPanama City
DTW - ECP
DTWECP
Detroit Metropolitan Wayne County
Tue 3/24
7:31 am-1:14 pm
1 stop6h 43m
Panama City NW Florida Beaches
Fri 3/27
5:03 pm-11:59 pm
1 stop5h 56m
$379
DetroitPanama City
DTW - ECP
DTWECP
Detroit Metropolitan Wayne County
Sat 3/21
4:45 pm-8:25 pm
1 stop4h 40m
Panama City NW Florida Beaches
Tue 3/24
7:00 am-5:30 pm
2 stops9h 30m
$394
DetroitPanama City
DTW - ECP
DTWECP
Detroit Metropolitan Wayne County
Mon 3/23
4:30 pm-8:35 pm
1 stop5h 05m
Panama City NW Florida Beaches
Mon 3/30
1:55 pm-12:15 am
2 stops9h 20m
$404
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from Detroit to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Panama City in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit Metropolitan Wayne County Airport-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit Metropolitan Wayne County Airport-Panama City, Florida flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit Metropolitan Wayne County Airport-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Detroit to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Detroit with our price prediction graph.
DTW-ECP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Panama City
Prices
More
How far ahead should I book a flight from Detroit Metropolitan Wayne County Airport to Panama City, Florida?
Use this chart to determine the optimal time to book a round-trip flight from Detroit to Panama City. Price data was last updated on March 6, 2026.
The price you pay for your flight from Detroit Metropolitan Wayne County Airport to Panama City, Florida may vary depending on when you book. For the best chance of a lower fare, look to book 12 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Panama City, Florida?
Currently, January is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Panama City, Florida (average of $92). Flying from Detroit Metropolitan Wayne County Airport to Panama City, Florida in November is currently the most expensive (average of $229). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What’s the top layover airport for flights from Detroit Metropolitan Wayne County Airport to Panama City, Florida?
Share of 1-stop round-trip flights from Detroit Metropolitan Wayne County Airport to Panama City, Florida chosen by Cheapflights users in the past 12 months, using the same layover each way.
Nashville (BNA) – chosen by Cheapflights users on 50% of 1-stop itineraries from Detroit Metropolitan Wayne County Airport to Panama City, Florida on Cheapflights.
What’s the cheapest layover airport for flights from Detroit Metropolitan Wayne County Airport to Panama City, Florida?
Average round-trip fare for 1-stop flights from Detroit Metropolitan Wayne County Airport to Panama City, Florida, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Chicago (ORD) is the most affordable 1-stop option, with an average round-trip price of $359.
What’s the fastest layover option from Detroit Metropolitan Wayne County Airport to Panama City, Florida?
Shortest average travel time for 1-stop one-way flights from Detroit Metropolitan Wayne County Airport to Panama City, Florida, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Nashville (BNA) have the shortest average one-way travel time for 1-stop routes: 6h 28m.
Which airport typically offers the quickest layover for flights from Detroit Metropolitan Wayne County Airport to Panama City, Florida?
Average layover duration for 1-stop one-way flights from Detroit Metropolitan Wayne County Airport to Panama City, Florida, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Chicago (ORD) offer the fastest connection on this route, with an average layover time of 2h 47m.
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated March 11, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Detroit Metropolitan Wayne County Airport to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Overall
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Overall
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Overall
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Overall
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Related info for your journey
Find useful and relevant information for your journey from Detroit to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Panama City?
Book flights to Panama City if you plan to visit one of these locationsMexico Beach
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Detroit and Panama City flights
Browse other Detroit and Panama City flight options. Last updated on March 11, 2026.
Other flights from Detroit
Browse through other flights departing from Detroit. Flights are based on user searches made on Cheapflights and were last updated on March 11, 2026.
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Top 4 airlines flying from Detroit to Panama City
Discover the top 4 airlines that operate flights from Detroit to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$196 | Average$309 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$228 | Average$335 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$228 | Average$382 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$238 | Average$359 | FlexibilityNo cancel fee | On-time69% |