HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama City

$336+ Cheap flights from Central America to Panama City, FL (ECP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/3. Fares are subject to change and may not be available on all flights or dates of travel.
SJO — ECP
Mar 6 — Mar 131
Fri 3/6
Fri 3/13
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Central America to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Central America to Panama City

Cheapest flights from Central America to Panama City
Explore the most affordable flight options available from Central America to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 4, 2026.

This Delta deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/37:00 am
SJO
-
ECP
1 stop11h 52m
Delta
Tue 3/1011:08 am
ECP
-
SJO
1 stop11h 07m
Delta
Deal found 2/4$336
This Delta deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/107:00 am
SJO
-
ECP
1 stop9h 58m
Delta
Tue 3/178:25 am
ECP
-
SJO
1 stop13h 50m
Delta
Deal found 2/4$418
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/177:00 am
SJO
-
ECP
1 stop9h 58m
Delta
Tue 3/3111:08 am
ECP
-
SJO
1 stop11h 07m
Delta
Deal found 2/2$512
This Avianca deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/35:00 am
SJO
-
ECP
2 stops14h 51m
Multiple Airlines
Tue 3/106:30 am
ECP
-
SJO
2 stops13h 25m
Multiple Airlines
Deal found 2/3$524
This Avianca deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/175:00 am
SJO
-
ECP
2 stops15h 57m
Multiple Airlines
Tue 3/316:30 am
ECP
-
SJO
2 stops13h 20m
Multiple Airlines
Deal found 2/2$535
This Avianca deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/309:40 am
SJO
-
ECP
2 stops11h 19m
Multiple Airlines
Thu 4/210:10 am
ECP
-
SJO
2 stops14h 30m
Multiple Airlines
Deal found 2/3$545
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2811:13 am
SJO
-
ECP
1 stop9h 44m
United Airlines
Mon 6/19:00 am
ECP
-
SJO
1 stop14h 39m
United Airlines
Deal found 2/2$585
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/187:00 am
SJO
-
ECP
1 stop7h 36m
Delta
Tue 3/318:25 am
ECP
-
SJO
1 stop13h 50m
Delta
Deal found 2/3$586
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/195:30 am
SJO
-
ECP
1 stop29h 34m
United Airlines
Thu 3/266:30 am
ECP
-
SJO
1 stop14h 09m
United Airlines
Deal found 2/1$625
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/177:00 am
SJO
-
ECP
2 stops14h 17m
American Airlines
Tue 3/316:41 am
ECP
-
SJO
1 stop8h 14m
American Airlines
Deal found 2/2$629
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/195:30 am
SJO
-
ECP
1 stop15h 27m
United Airlines
Mon 3/235:03 pm
ECP
-
SJO
1 stop20h 12m
United Airlines
Deal found 2/1$630

Find flight deals from Central America to Panama City

Keep the following information in mind while searching for Central America to Panama City flight deals. Data was last updated February 4, 2026.

Round-trip from

$336
(Delta)

Popular in

March

Cheapest in

September

Average price

$467
From Central America to Panama City NW Florida Beaches
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($28 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Central America to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from Central America to Panama City that are best for you.

Fly from

Central America

Fly to

Panama City

Route

Depart

Return

Price

San JoséPanama City

SJO - ECP

SJOECP

San José Juan Santamaria Intl

Tue 3/3

7:00 am-6:52 pm

1 stop11h 52m

Panama City NW Florida Beaches

Tue 3/10

1:30 pm-9:15 pm

1 stop8h 45m

$336

San JoséPanama City

SJO - ECP

SJOECP

San José Juan Santamaria Intl

Tue 3/10

7:00 am-3:36 pm

1 stop7h 36m

Panama City NW Florida Beaches

Tue 3/17

9:25 am-9:15 pm

1 stop12h 50m

$418

San JoséPanama City

SJO - ECP

SJOECP

San José Juan Santamaria Intl

Tue 3/17

7:00 am-5:58 pm

1 stop9h 58m

Panama City NW Florida Beaches

Tue 3/31

11:08 am-9:15 pm

1 stop11h 07m

$512

San JoséPanama City

SJO - ECP

SJOECP

San José Juan Santamaria Intl

Wed 3/18

5:00 am-4:12 pm

2 stops10h 12m

Panama City NW Florida Beaches

Tue 3/31

10:10 am-6:50 pm

2 stops9h 40m

$535

San JoséPanama City

SJO - ECP

SJOECP

San José Juan Santamaria Intl

Tue 3/17

5:00 am-9:57 pm

2 stops15h 57m

Panama City NW Florida Beaches

Tue 3/31

6:30 am-6:50 pm

2 stops13h 20m

$535

San JoséPanama City

SJO - ECP

SJOECP

San José Juan Santamaria Intl

Mon 3/30

9:40 am-9:59 pm

2 stops11h 19m

Panama City NW Florida Beaches

Thu 4/2

10:10 am-11:40 pm

2 stops14h 30m

$545

San JoséPanama City

SJO - ECP

SJOECP

San José Juan Santamaria Intl

Thu 5/28

11:13 am-9:57 pm

1 stop9h 44m

Panama City NW Florida Beaches

Mon 6/1

9:00 am-10:39 pm

1 stop14h 39m

$585

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/3

Best time to book a flight from Central America to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Central America with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Central America to Panama City

What is the cheapest month to book a flight from Central America to Panama City, Florida?

Currently, November is the cheapest month in which you can book a flight from Central America to Panama City, Florida (average of $203). Flying from Central America to Panama City, Florida in September is currently the most expensive (average of $299). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated February 4, 2026.
Read reviews from past customers who have flown United Airlines and American Airlines from Central America to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,236 reviews

Comfort

7.3

Entertainment

7.1

Food

6.6

Overall

7.4

Crew

8.1

Boarding

7.7

Reviews

1 / 20
6.0
Good

Gerry,Jan 2026

YVR - DEN

Seats were uncomfortable. Second leg of my flight on United had much more comfortable seats
United Airlines
7.4
Good
9,236 reviews
United Airlines
7.4
Good
9,236 reviews

Comfort

7.3

Entertainment

7.1

Food

6.6

Overall

7.4

Crew

8.1

Boarding

7.7

Reviews

1 / 20
6.0
Good

Gerry,Jan 2026

YVR - DEN

Seats were uncomfortable. Second leg of my flight on United had much more comfortable seats
American Airlines
7.2
Good
11,222 reviews
United Airlines
7.4
Good
9,236 reviews

Comfort

7.3

Entertainment

7.1

Food

6.6

Overall

7.4

Crew

8.1

Boarding

7.7

Reviews

1 / 20
6.0
Good

Gerry,Jan 2026

YVR - DEN

Seats were uncomfortable. Second leg of my flight on United had much more comfortable seats

Related info for your journey

Find useful and relevant information for your journey from Central America to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Central America?

    Located just 16.0 mi from the city center, Panama City NW Florida Beaches (ECP) is the airport most travelers will use when flying to Panama City from Central America.

  • How long is the flight from Central America to Panama City, Florida?

    Departing from Central America to Panama City, Florida will take you 11h 52m. The distance between Central America and Panama City, Florida is about 1410 mi.

  • Can I find deals for flights from Central America to Panama City that include hotel bookings?

    Yes. In addition to deals on Central America to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Central America to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Central America to Panama City.

  • Can I find deals for business class flights from Central America to Panama City?

    Yes. Cheapflights offers flight deals from Central America to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Central America to Panama City, Florida?

    Currently, November is the cheapest month in which you can book a flight from Central America to Panama City, Florida (average of $203). Flying from Central America to Panama City, Florida in September is currently the most expensive (average of $299). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Central America to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Fort Lauderdale flights
John F Kennedy Intl to Miami flights
Newark to Fort Lauderdale flights
Newark to Miami flights
LaGuardia to Miami flights
LaGuardia to Fort Lauderdale flights
Newark to West Palm Beach flights
John F Kennedy Intl to Orlando flights
John F Kennedy Intl to West Palm Beach flights
Newark to Orlando flights
Dulles Intl to Miami flights
Boston to Fort Lauderdale flights
Newark to Tampa flights
Reagan-National to Miami flights
Baltimore to Fort Lauderdale flights
Boston to Miami flights
John F Kennedy Intl to Tampa flights
LaGuardia to Orlando flights
LaGuardia to West Palm Beach flights
LaGuardia to Tampa flights
Minneapolis to Orlando flights
Detroit to Orlando flights
Dulles Intl to Orlando flights
Boston to Tampa flights
Detroit to Fort Lauderdale flights
Boston to Orlando flights
O'Hare Intl to Orlando flights
Dulles Intl to Fort Lauderdale flights
Reagan-National to Orlando flights
Baltimore to Miami flights
Philadelphia to Miami flights
Minneapolis to Fort Myers flights
Newark to Fort Myers flights
O'Hare Intl to Fort Lauderdale flights
John F Kennedy Intl to Fort Myers flights
Philadelphia to Fort Lauderdale flights
Dallas/Fort Worth to Orlando flights
O'Hare Intl to Miami flights
Baltimore to Orlando flights
Philadelphia to Orlando flights
O'Hare Intl to Tampa flights
Cleveland to Orlando flights
Reagan-National to Fort Lauderdale flights
Los Angeles to Miami flights
Detroit to Miami flights
Boston to West Palm Beach flights
Los Angeles to Orlando flights
Minneapolis to Tampa flights
White Plains to Orlando flights
Detroit to Tampa flights

Top 2 airlines flying from Central America to Panama City

Discover the top 2 airlines that operate flights from Central America to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$458Average$646FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$510Average$617FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.