North Carolina

$184+ Cheap flights from Odessa, TX to North Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/8. Fares are subject to change and may not be available on all flights or dates of travel.
MAF — CLT
Apr 18 — Apr 251
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Cheap flight deals from Odessa to North Carolina

Cheapest flights from Odessa to North Carolina
Explore the most affordable flight options available from Odessa to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 19, 2026.

This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2211:45 am
MAF
-
TYS
2 stops6h 55m
Southwest
Wed 4/297:05 am
TYS
-
MAF
2 stops8h 35m
Southwest
Deal found 3/19$321
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/221:45 pm
MAF
-
TYS
1 stop7h 44m
United Airlines
Wed 4/294:30 pm
TYS
-
MAF
1 stop6h 45m
United Airlines
Deal found 3/19$338
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2611:45 am
MAF
-
TYS
2 stops6h 55m
Southwest
Wed 6/102:45 pm
TYS
-
MAF
1 stop4h 45m
Southwest
Deal found 3/18$350
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:00 am
MAF
-
ILM
2 stops9h 28m
United Airlines
Wed 8/267:30 am
ILM
-
MAF
2 stops15h 38m
United Airlines
Deal found 3/17$374
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/115:00 am
MAF
-
TYS
1 stop6h 30m
American Airlines
Fri 5/154:09 pm
TYS
-
MAF
1 stop6h 58m
American Airlines
Deal found 3/17$376
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/289:15 am
MAF
-
MYR
1 stop5h 52m
American Airlines
Sat 5/24:52 pm
MYR
-
MAF
1 stop6h 15m
American Airlines
Deal found 3/16$377
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:00 am
MAF
-
MYR
2 stops8h 17m
United Airlines
Wed 4/1511:00 am
MYR
-
MAF
2 stops12h 15m
United Airlines
Deal found 3/18$378
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:15 am
MAF
-
MYR
2 stops9h 20m
Southwest
Sat 5/21:00 pm
MYR
-
MAF
2 stops9h 00m
Southwest
Deal found 3/16$382
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:00 am
MAF
-
MYR
2 stops8h 18m
United Airlines
Tue 5/1211:30 am
MYR
-
MAF
2 stops12h 45m
United Airlines
Deal found 3/17$383
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:50 am
MAF
-
RDU
1 stop7h 55m
Southwest
Tue 5/1911:15 am
RDU
-
MAF
1 stop7h 25m
Southwest
Deal found 3/15$391
This United Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/141:45 pm
MAF
-
TYS
1 stop7h 44m
United Airlines
Wed 4/154:30 pm
TYS
-
MAF
1 stop6h 45m
United Airlines
Deal found 3/16$391
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/115:30 am
MAF
-
RDU
1 stop9h 50m
Southwest
Sat 4/1812:00 pm
RDU
-
MAF
1 stop5h 00m
Southwest
Deal found 3/16$396

Find flight deals from Odessa to North Carolina

Keep the following information in mind while searching for Odessa to North Carolina flight deals. Data was last updated March 19, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$350
(Southwest)

One-way from

$184
(American Airlines)
Provider with most accurate pricing for Midland Intl-Raleigh-Durham flight deals.
Provider most trusted by Cheapflights users for Midland Intl-Raleigh-Durham flights.
From Odessa to North Carolina
One-way flight from Odessa to North Carolina

Cheapflights Fare Finder

 
Customize your flight search to find flights from Odessa to North Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 19, 2026.
Use the filters below to find and compare flights from Odessa to North Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MidlandKnoxville

MAF - TYS

MAFTYS

Midland Intl

Wed 4/22

6:50 am-2:20 pm

1 stop6h 30m

Knoxville McGhee Tyson

Wed 4/29

7:05 am-2:05 pm

2 stops8h 00m

$340

MidlandKnoxville

MAF - TYS

MAFTYS

Midland Intl

Tue 5/26

11:45 am-7:40 pm

2 stops6h 55m

Knoxville McGhee Tyson

Wed 6/10

2:45 pm-6:30 pm

1 stop4h 45m

$350
Quickest round-trip

MidlandKnoxville

MAF - TYS

MAFTYS

Midland Intl

Mon 5/11

6:16 pm-11:56 pm

1 stop4h 40m

Knoxville McGhee Tyson

Fri 5/15

6:54 pm-12:06 am

1 stop6h 12m

$376

MidlandMyrtle Beach

MAF - MYR

MAFMYR

Midland Intl

Tue 4/14

5:00 am-2:17 pm

2 stops8h 17m

Myrtle Beach Intl

Wed 4/15

11:00 am-10:15 pm

2 stops12h 15m

$378

MidlandMyrtle Beach

MAF - MYR

MAFMYR

Midland Intl

Tue 4/28

7:15 am-5:35 pm

2 stops9h 20m

Myrtle Beach Intl

Sat 5/2

1:00 pm-9:00 pm

2 stops9h 00m

$382

MidlandMyrtle Beach

MAF - MYR

MAFMYR

Midland Intl

Sat 5/9

5:00 am-2:18 pm

2 stops8h 18m

Myrtle Beach Intl

Tue 5/12

11:30 am-11:15 pm

2 stops12h 45m

$383

MidlandKnoxville

MAF - TYS

MAFTYS

Midland Intl

Tue 4/14

1:45 pm-10:29 pm

1 stop7h 44m

Knoxville McGhee Tyson

Wed 4/15

4:30 pm-10:15 pm

1 stop6h 45m

$391

MidlandRaleigh

MAF - RDU

MAFRDU

Midland Intl

Sat 4/11

8:10 am-5:30 pm

2 stops8h 20m

Raleigh-Durham

Sat 4/18

12:00 pm-9:00 pm

2 stops10h 00m

$401

MidlandRaleigh

MAF - RDU

MAFRDU

Midland Intl

Sun 5/3

6:05 pm-12:15 am

1 stop5h 10m

Raleigh-Durham

Tue 5/12

5:00 pm-10:15 pm

1 stop6h 15m

$412

MidlandCharlotte

MAF - CLT

MAFCLT

Midland Intl

Sat 5/9

7:00 am-3:15 pm

1 stop7h 15m

Charlotte Douglas

Tue 5/12

4:46 pm-9:46 pm

1 stop6h 00m

$444

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/18

Showing 1-10 of 35 resultsSorted by cheapest first
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Best time to book a flight from Odessa to North Carolina

Have a flexible travel schedule? Discover the best time to fly to North Carolina from Odessa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Odessa to North Carolina
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing North Carolina

Get insights into the airlines that provide service to North Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to North Carolina. Reviews last updated March 19, 2026.
Read reviews from past customers who have flown United Airlines and American Airlines from Odessa to North Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Crew

8.1

Overall

7.4

Boarding

7.7

Comfort

7.3

Food

6.6

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Crew

8.1

Overall

7.4

Boarding

7.7

Comfort

7.3

Food

6.6

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Crew

8.1

Overall

7.4

Boarding

7.7

Comfort

7.3

Food

6.6

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Related info for your journey

Find useful and relevant information for your journey from Odessa to North Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Odessa to North Carolina?

    Southwest, American Airlines, and United Airlines can get you from Odessa to North Carolina in just under 4h 40m. Your travel time can differ by up to 3h 37m. Odessa and North Carolina are separated by a distance of 1076 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Odessa to North Carolina?

  • Can I find deals for flights from Odessa to North Carolina that include hotel bookings?

    Yes. In addition to deals on Odessa to North Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Odessa to North Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Odessa to North Carolina.

  • Can I find deals for business class flights from Odessa to North Carolina?

    Yes. Cheapflights offers flight deals from Odessa to North Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Odessa to North Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Odessa to North Carolina

Discover the top 2 airlines that operate flights from Odessa to North Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 19, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$269Average$368FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$340Average$476FlexibilityNo cancel feeOn-time71%

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