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North Carolina

$378+ Cheap flights from La Crosse (LSE) to North Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/7. Fares are subject to change and may not be available on all flights or dates of travel.
LSE — RDU
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from La Crosse to North Carolina

Keep the following information in mind while searching for La Crosse to North Carolina flight deals. Data was last updated September 17, 2025.

Round-trip from

$410
(American Airlines)

One-way from

$378
(American Airlines)

Popular in

June

Cheapest in

December

Average price

$507
From La Crosse to North Carolina
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One-way flight from La Crosse to North Carolina
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Highest demand for flights based on searches. 33% potential increase in price ($296 potential increase over avg. RT price).
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Cheapest flight prices on average. 12% potential price decrease ($67 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from La Crosse to North Carolina

Cheapest flights from La Crosse to North Carolina
Explore the most affordable flight options available from La Crosse to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/216:15 pmLSE - RDU
1 stop4h 38mAmerican Airlines
Tue 10/287:00 amRDU - LSE
1 stop4h 24mAmerican Airlines
Deal found 9/16$410
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/710:54 amLSE - AVL
1 stop6h 13mAmerican Airlines
Tue 11/411:38 amAVL - LSE
1 stop5h 32mAmerican Airlines
Deal found 9/15$420
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/196:00 amLSE - AVL
1 stop3h 56mAmerican Airlines
Sun 11/2311:21 amAVL - LSE
1 stop7h 22mAmerican Airlines
Deal found 9/17$437
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/306:00 amLSE - ORF
2 stops9h 44mAmerican Airlines
Sat 10/117:00 amORF - LSE
1 stop4h 24mAmerican Airlines
Deal found 9/17$438
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/610:00 amLSE - CLT
1 stop6h 10mAmerican Airlines
Sun 12/146:04 pmCLT - LSE
1 stop6h 48mAmerican Airlines
Deal found 9/16$451
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/146:15 pmLSE - CLT
1 stop4h 38mAmerican Airlines
Fri 11/141:45 pmCLT - LSE
1 stop4h 47mAmerican Airlines
Deal found 9/15$458
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/166:00 amLSE - GSO
1 stop4h 03mAmerican Airlines
Mon 10/208:17 pmGSO - LSE
1 stop4h 09mAmerican Airlines
Deal found 9/16$464
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/66:02 pmLSE - RDU
1 stop4h 53mAmerican Airlines
Mon 11/106:00 amRDU - LSE
1 stop4h 20mAmerican Airlines
Deal found 9/16$464
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/116:00 amLSE - AVL
1 stop4h 30mAmerican Airlines
Sat 11/16:37 pmAVL - LSE
1 stop4h 28mAmerican Airlines
Deal found 9/17$469
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/196:30 pmLSE - CLT
1 stop4h 23mAmerican Airlines
Tue 9/234:17 pmCLT - LSE
1 stop6h 51mAmerican Airlines
Deal found 9/15$475
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/186:00 amLSE - AVL
1 stop3h 56mAmerican Airlines
Sat 11/226:25 pmAVL - LSE
1 stop6h 24mAmerican Airlines
Deal found 9/17$480
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/186:00 amLSE - AVL
1 stop3h 56mAmerican Airlines
Mon 11/2411:21 amAVL - LSE
1 stop7h 22mAmerican Airlines
Deal found 9/17$507

Cheapflights Fare Finder

 
Customize your flight search to find flights from La Crosse to North Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from La Crosse to North Carolina that are best for you.

Fly from

La Crosse

Fly to

North Carolina

Route

Depart

Return

Price

La CrosseRaleigh

LSE - RDU

LSERDU

La Crosse

Tue 10/21

6:00 am-4:06 pm

2 stops9h 06m

Raleigh-Durham

Tue 10/28

7:00 am-10:24 am

1 stop4h 24m

$416

La CrosseAsheville

LSE - AVL

LSEAVL

La Crosse

Sat 10/11

6:00 am-11:30 am

1 stop4h 30m

Asheville Regional

Sat 11/1

12:00 pm-5:45 pm

1 stop6h 45m

$420

La CrosseAsheville

LSE - AVL

LSEAVL

La Crosse

Tue 10/7

10:54 am-6:07 pm

1 stop6h 13m

Asheville Regional

Tue 11/4

11:38 am-4:10 pm

1 stop5h 32m

$420

La CrosseNorfolk

LSE - ORF

LSEORF

La Crosse

Tue 9/30

6:00 am-4:44 pm

2 stops9h 44m

Norfolk

Sat 10/11

7:00 am-10:24 am

1 stop4h 24m

$438

La CrosseCharlotte

LSE - CLT

LSECLT

La Crosse

Sat 12/6

10:00 am-7:06 pm

2 stops8h 06m

Charlotte Douglas

Sun 12/14

1:01 pm-5:38 pm

1 stop5h 37m

$457

La CrosseCharlotte

LSE - CLT

LSECLT

La Crosse

Tue 10/14

6:15 pm-11:53 pm

1 stop4h 38m

Charlotte Douglas

Fri 11/14

1:45 pm-5:32 pm

1 stop4h 47m

$458

La CrosseGreensboro

LSE - GSO

LSEGSO

La Crosse

Thu 10/16

6:00 am-11:03 am

1 stop4h 03m

Greensboro/H. Point

Mon 10/20

8:17 pm-11:26 pm

1 stop4h 09m

$464

La CrosseRaleigh

LSE - RDU

LSERDU

La Crosse

Thu 11/6

6:02 pm-11:55 pm

1 stop4h 53m

Raleigh-Durham

Mon 11/10

6:00 am-9:20 am

1 stop4h 20m

$464

La CrosseCharlotte

LSE - CLT

LSECLT

La Crosse

Tue 10/7

6:00 am-12:35 pm

1 stop5h 35m

Charlotte Douglas

Sun 11/2

6:00 pm-11:49 pm

1 stop6h 49m

$475

La CrosseGreensboro

LSE - GSO

LSEGSO

La Crosse

Tue 3/10

4:46 pm-9:27 pm

1 stop3h 41m

Greensboro/H. Point

Sat 3/14

11:28 am-2:18 pm

1 stop3h 50m

$510

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 20 results
1
2

Best time to book a flight from La Crosse to North Carolina

Have a flexible travel schedule? Discover the best time to fly to North Carolina from La Crosse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from La Crosse to North Carolina

What is the cheapest month to book a flight from La Crosse to North Carolina?

Currently, August is the cheapest month in which you can book a flight from La Crosse to North Carolina (average of $206). Flying from La Crosse to North Carolina in March is currently the most expensive (average of $293). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing North Carolina

Get insights into the airlines that provide service to North Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to North Carolina. Reviews last updated September 17, 2025.
Read reviews from past customers who have flown American Airlines from La Crosse to North Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Overall

7.2

Boarding

7.5

Food

6.4

Comfort

7.2

Crew

8.0

Entertainment

6.9

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2025

MYR - CLT

This flight was impacted by a nearly 4, yes 4 hour delay. They replaced a 777 with another one and it had to be cleaned and catered before we could depart. Great crew did it without complaint.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Overall

7.2

Boarding

7.5

Food

6.4

Comfort

7.2

Crew

8.0

Entertainment

6.9

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2025

MYR - CLT

This flight was impacted by a nearly 4, yes 4 hour delay. They replaced a 777 with another one and it had to be cleaned and catered before we could depart. Great crew did it without complaint.

Related info for your journey

Find useful and relevant information for your journey from La Crosse to North Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from La Crosse to North Carolina?

    If you book a flight to North Carolina from La Crosse, you will be flying from La Crosse, which is the city’s only airport. La Crosse (LSE) is located 5.4 mi from the center of La Crosse.

  • How long is the flight from La Crosse to North Carolina?

    Departing from La Crosse to North Carolina will take you 9h 06m. There are 859 mi between La Crosse and North Carolina.

  • What are the most popular routes from La Crosse to North Carolina?

    The most popular route from La Crosse to North Carolina is La Crosse - Charlotte Douglas. You may also consider La Crosse - Asheville Regional or La Crosse - Greensboro/H. Point.

  • Can I find deals for flights from La Crosse to North Carolina that include hotel bookings?

    Yes. In addition to deals on La Crosse to North Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from La Crosse to North Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from La Crosse to North Carolina.

  • Can I find deals for business class flights from La Crosse to North Carolina?

    Yes. Cheapflights offers flight deals from La Crosse to North Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from La Crosse to North Carolina?

    Currently, August is the cheapest month in which you can book a flight from La Crosse to North Carolina (average of $206). Flying from La Crosse to North Carolina in March is currently the most expensive (average of $293). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for La Crosse to North Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from La Crosse to North Carolina

Discover the top airline that operate flights from La Crosse to North Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$345Average$468FlexibilityNo cancel feeOn-time71%

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