What are the cheapest airlines flying from Knoxville to New Orleans round-trip?

Currently priced at $224, American Airlines will fly you from Knoxville to New Orleans and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Delta and United Airlines - these airlines can fly you to your destination from $249 and $284, respectively. Users have found that American Airlines is 40% cheaper than the other options available to this destination.

What are the most popular airlines that fly from Knoxville to New Orleans?

American Airlines, Delta and United Airlines are the most popular airlines when flying from Knoxville to New Orleans.

What is the cheapest day to fly round-trip from Knoxville to New Orleans?

Flying to your destination on a Wednesday can be more expensive, but this shouldn’t discourage you from finding affordable options to get to New Orleans. Check prices with Cheapflights to find a great deal for your trip.

How far in advance should I book a flight from Knoxville to New Orleans?

When searching for a good deal, it’s best to be prepared for potential fluctuations in price. We recommend booking at least 57 days in advance, which can save you up to 51% on flights from Knoxville to New Orleans compared to booking the week you need them. Waiting 57 days out may not be for everyone, so we have options available for flights within the next two weeks, with the lowest price starting at $283. For sooner than that we have options available in the next 3 days from $338.

What is the cheapest month to fly from Knoxville to New Orleans?

The best pricing can be found in the month of September. Prices to New Orleans from Knoxville average $377. You can even find prices in September for less than $377, as users have found deals to New Orleans from as low as $199. The month of November appears to be one of the more expensive times to travel to New Orleans from Knoxville. Flying in the targeted month can save you up to 26%.

Can I find deals for flights from Knoxville to New Orleans that include hotel bookings?

Yes. In addition to deals on Knoxville to New Orleans flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Knoxville to New Orleans?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to New Orleans.

Can I find deals for business class flights from Knoxville to New Orleans?

Yes. Cheapflights offers flight deals from Knoxville to New Orleans by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$99+ Flights from Knoxville to New Orleans

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Knoxville to New Orleans with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Knoxville McGhee Tyson to New Orleans Louis Armstrong are usually found in September or August, booked 77 days in advance, depart on a Saturday or Friday and return on a Wednesday

Cheap flight deals from Knoxville to New Orleans

Round-trip from	$198 (Mytrip)
One-way from	$99 (Mytrip)
Popular in	November
Cheapest in	September
Average price	$343

From Knoxville McGhee Tyson to New Orleans Louis Armstrong

Search Deals

One-way flight from Knoxville McGhee Tyson to New Orleans Louis Armstrong

Search Deals

Highest demand for flights based on searches. 9% potential increase in price ($40 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in June 2025

Search Deals

Find flight deals from Knoxville to New Orleans

Cheapest flights from Knoxville to New Orleans
Explore the most affordable flight options available from Knoxville to New Orleans. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

vie. 8/156:00 amTYS - MSY

1 stop26h 02mMultiple Airlines

jue. 8/211:40 pmMSY - TYS

1 stop26h 58mMultiple Airlines

Deal found 6/11

$198

mié. 7/22:16 pmTYS - MSY

1 stop5h 45mAmerican Airlines

sáb. 7/126:16 pmMSY - TYS

1 stop4h 36mAmerican Airlines

Deal found 6/11

$224

vie. 7/112:36 pmTYS - MSY

1 stop4h 40mDelta

mar. 7/151:05 pmMSY - TYS

1 stop3h 07mDelta

Deal found 6/11

$249

jue. 6/265:45 amTYS - MSY

1 stop5h 28mUnited Airlines

lun. 6/308:00 amMSY - TYS

1 stop5h 58mUnited Airlines

Deal found 6/11

$284

Best flights from Knoxville to New Orleans
Discover carefully curated flight deals from Knoxville to New Orleans that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated junio 12, 2025.

vie. 8/156:00 amTYS - MSY

1 stop26h 02mMultiple Airlines

jue. 8/211:40 pmMSY - TYS

1 stop26h 58mMultiple Airlines

Deal found 6/11

$198

mié. 7/22:16 pmTYS - MSY

1 stop5h 45mAmerican Airlines

sáb. 7/126:16 pmMSY - TYS

1 stop4h 36mAmerican Airlines

Deal found 6/11

$224

vie. 7/112:36 pmTYS - MSY

1 stop4h 40mDelta

mar. 7/151:05 pmMSY - TYS

1 stop3h 07mDelta

Deal found 6/11

$249

jue. 6/265:45 amTYS - MSY

1 stop5h 28mUnited Airlines

lun. 6/308:00 amMSY - TYS

1 stop5h 58mUnited Airlines

Deal found 6/11

$284

Last-minute flights from Knoxville to New Orleans
Discover last-minute flight deals from Knoxville to New Orleans. Data last updated junio 12, 2025 and is based on user searches.

jue. 6/199:04 pmTYS - MSY

2 stops26h 36mMultiple Airlines

dom. 6/229:10 pmMSY - TYS

2 stops24h 17mMultiple Airlines

Deal found 6/10

$332

dom. 6/225:45 amTYS - MSY

1 stop3h 11mDelta

mié. 7/236:25 amMSY - TYS

1 stop3h 43mDelta

Deal found 6/10

$304

jue. 6/265:45 amTYS - MSY

1 stop5h 28mUnited Airlines

lun. 6/308:00 amMSY - TYS

1 stop5h 58mUnited Airlines

Deal found 6/11

$284

mié. 7/27:01 pmTYS - MSY

1 stop12h 08mMultiple Airlines

mar. 7/89:10 pmMSY - TYS

1 stop24h 13mMultiple Airlines

Deal found 6/10

$200

mié. 7/22:16 pmTYS - MSY

1 stop5h 45mAmerican Airlines

sáb. 7/126:16 pmMSY - TYS

1 stop4h 36mAmerican Airlines

Deal found 6/11

$224

vie. 7/112:36 pmTYS - MSY

1 stop4h 40mDelta

mar. 7/151:05 pmMSY - TYS

1 stop3h 07mDelta

Deal found 6/11

$249

One-way flights from Knoxville to New Orleans
Search for one-way flight options from Knoxville to New Orleans. Find affordable one-way fares based on user searches. Data last updated junio 12, 2025.

lun. 7/216:00 amTYS - MSY

1 stop14h 15mMultiple Airlines

Deal found 6/10

$99

mié. 6/187:00 amTYS - MSY

1 stop3h 26mDelta

Deal found 6/12

$375

mié. 6/185:45 amTYS - MSY

2 stops16h 53mUnited Airlines

Deal found 6/10

$568

Cheapflights Fare Finder

Use the filters below to find and compare flights from Knoxville to New Orleans that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

vie. 8/15

6:00 am-7:02 am

1 stop26h 02m

New Orleans Louis Armstrong

jue. 8/21

1:40 pm-5:38 pm

1 stop26h 58m

$198

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

mié. 7/2

2:16 pm-7:01 pm

1 stop5h 45m

New Orleans Louis Armstrong

sáb. 7/12

6:16 pm-11:52 pm

1 stop4h 36m

$224

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

vie. 7/11

2:36 pm-6:16 pm

1 stop4h 40m

New Orleans Louis Armstrong

mar. 7/15

1:05 pm-5:12 pm

1 stop3h 07m

$249

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

jue. 6/26

5:45 am-10:13 am

1 stop5h 28m

New Orleans Louis Armstrong

lun. 6/30

8:00 am-2:58 pm

1 stop5h 58m

$284

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

lun. 7/21

6:00 am-7:15 pm

1 stop14h 15m

$99

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

mié. 6/18

7:00 am-9:26 am

1 stop3h 26m

$375

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

mié. 6/18

5:45 am-9:38 pm

2 stops16h 53m

$568

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Best time to book a flight from Knoxville to New Orleans

Have a flexible travel schedule? Discover the best time to fly to New Orleans from Knoxville with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to New Orleans

How far ahead should I book a flight from Knoxville to New Orleans?

The price you pay for your flight from Knoxville to New Orleans may vary depending on when you book. For the best chance of a lower fare, look to book 56 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Knoxville to New Orleans?

Currently, August is the cheapest month in which you can book a flight from Knoxville to New Orleans (average of $256). Flying from Knoxville to New Orleans in April is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to MSY?

A simple way to save on the total cost of your ticket is to fly from Knoxville to New Orleans in the afternoon. If you’re flexible enough to do this you can expect to save up to 13% on your trip compared to booking a flight in the morning.

What is the cheapest day to fly from Knoxville to New Orleans?

Travelers seeking maximum savings on their Knoxville to New Orleans flight should consider departing on Sunday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in New Orleans by month

In terms of precipitation, rainfall in New Orleans ranges from 3.3 - 6.4 inches per month. June is typically the wettest month, when rainfall can reach 6.4 in. October is typically the driest time to visit New Orleans when rainfall is around 3.3 in.

Temperature in New Orleans by month

If weather is an important factor for your trip to New Orleans, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 82.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing New Orleans

Delta

8.0

Very good

7,946 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,946 reviews

Delta

8.0

Very good

7,946 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

United Airlines

7.4

Good

8,790 reviews

Delta

8.0

Very good

7,946 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,946 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What are the cheapest airlines flying from Knoxville to New Orleans round-trip?
Currently priced at $224, American Airlines will fly you from Knoxville to New Orleans and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Delta and United Airlines - these airlines can fly you to your destination from $249 and $284, respectively. Users have found that American Airlines is 40% cheaper than the other options available to this destination.
Can I find deals for flights from Knoxville to New Orleans that include hotel bookings?
Yes. In addition to deals on Knoxville to New Orleans flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Knoxville to New Orleans?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to New Orleans.
Can I find deals for business class flights from Knoxville to New Orleans?
Yes. Cheapflights offers flight deals from Knoxville to New Orleans by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Knoxville to New Orleans?
Currently, August is the cheapest month in which you can book a flight from Knoxville to New Orleans (average of $256). Flying from Knoxville to New Orleans in April is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Metairie

Kenner

Slidell

Houma

Covington

Gretna

Thibodaux

Hammond

Gonzales

Browse thousands of different options on Cheapflights for your next trip

Top 3 airlines flying from Knoxville to New Orleans

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$218	Average$344	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$228	Average$394	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$253	Average$408	FlexibilityNo cancel fee	On-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$99+ Cheap flights from Knoxville to New Orleans (TYS - MSY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/21. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Knoxville to New Orleans with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Knoxville McGhee Tyson to New Orleans Louis Armstrong are usually found in September or August, booked 77 days in advance, depart on a Saturday or Friday and return on a Wednesday

Cheap flight deals from Knoxville to New Orleans

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Knoxville to New Orleans

Cheapest flights from Knoxville to New OrleansExplore the most affordable flight options available from Knoxville to New Orleans. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

Explore the most affordable flight options available from Knoxville to New Orleans. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Knoxville to New Orleans that are best for you.

Best time to book a flight from Knoxville to New Orleans

Have a flexible travel schedule? Discover the best time to fly to New Orleans from Knoxville with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to New Orleans

How far ahead should I book a flight from Knoxville to New Orleans?

Use this chart to determine the optimal time to book a round-trip flight from Knoxville to New Orleans. Price data was last updated on June 9, 2025.

What is the cheapest month to book a flight from Knoxville to New Orleans?

What is the cheapest time of day to fly from TYS to MSY?

Find hourly flight availability from Knoxville to New Orleans. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated junio 12, 2025.

What is the cheapest day to fly from Knoxville to New Orleans?

Use this chart to determine the cheapest time to fly round-trip from Knoxville to New Orleans. Price data was last updated on December 16, 2024.

Rainfall in New Orleans by month

Plan your trip to New Orleans by taking into account the average rainfall totals by month.

Temperature in New Orleans by month

Plan your trip to New Orleans by taking into account the average temperature totals by month.

Reviews of airlines servicing New Orleans

Related info for your journey

Find useful and relevant information for your journey from Knoxville to New Orleans. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Knoxville to New Orleans round-trip?

Can I find deals for flights from Knoxville to New Orleans that include hotel bookings?

How can I find direct flights from Knoxville to New Orleans?

Can I find deals for business class flights from Knoxville to New Orleans?

What is the cheapest month to book a flight from Knoxville to New Orleans?

Traveling to a place near Knoxville?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Knoxville to New Orleans

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Knoxville to New Orleans

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Knoxville to New Orleans
Explore the most affordable flight options available from Knoxville to New Orleans. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.