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$112+ Cheap flights from Knoxville to New Orleans (TYS - MSY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/19. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MSY
Feb 19 — Feb 261
Thu 2/19
Thu 2/26
1 adult, Economy
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Cheap flight deals from Knoxville to New Orleans

Cheapest flights from Knoxville to New Orleans
Explore the most affordable flight options available from Knoxville to New Orleans. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 20, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/19:42 pm
TYS
-
MSY
1 stop17h 11m
Multiple Airlines
Sat 3/77:27 pm
MSY
-
TYS
1 stop25h 59m
Multiple Airlines
Deal found 1/17$212
This Kiwi.com deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/12:00 pm
TYS
-
MSY
1 stop21h 20m
Allegiant Air
Fri 2/611:10 am
MSY
-
TYS
1 stop10h 11m
Allegiant Air
Deal found 1/18$230
This Kiwi.com deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/308:58 am
TYS
-
MSY
1 stop15h 21m
Multiple Airlines
Sat 4/410:30 am
MSY
-
TYS
2 stops30h 13m
Multiple Airlines
Deal found 1/18$239
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/159:44 pm
TYS
-
MSY
1 stop18h 16m
Multiple Airlines
Thu 2/198:36 pm
MSY
-
TYS
1 stop19h 23m
Multiple Airlines
Deal found 1/19$252
This Kiwi.com deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:51 pm
TYS
-
MSY
1 stop19h 48m
Multiple Airlines
Mon 3/26:10 am
MSY
-
TYS
1 stop11h 21m
Multiple Airlines
Deal found 1/18$254
This Kiwi.com deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/269:42 pm
TYS
-
MSY
1 stop17h 11m
Multiple Airlines
Mon 3/26:10 am
MSY
-
TYS
1 stop11h 21m
Multiple Airlines
Deal found 1/18$272
This Kiwi.com deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/12:00 pm
TYS
-
MSY
1 stop21h 20m
Multiple Airlines
Fri 2/66:05 am
MSY
-
TYS
2 stops10h 23m
Multiple Airlines
Deal found 1/18$274
This Kiwi.com deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/213:48 pm
TYS
-
MSY
1 stop19h 23m
Multiple Airlines
Sat 4/253:30 pm
MSY
-
TYS
1 stop28h 10m
Multiple Airlines
Deal found 1/18$276
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/147:00 am
TYS
-
MSY
1 stop12h 25m
Multiple Airlines
Tue 3/177:20 pm
MSY
-
TYS
1 stop14h 20m
Multiple Airlines
Deal found 1/19$277
This Kiwi.com deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/212:55 pm
TYS
-
MSY
2 stops20h 27m
Multiple Airlines
Tue 2/38:57 pm
MSY
-
TYS
1 stop18h 00m
Multiple Airlines
Deal found 1/18$278

Find flight deals from Knoxville to New Orleans

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to New Orleans (MSY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 20, 2026.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$212
(Kiwi.com)

One-way from

$112
(Kiwi.com)

Popular in

February

Cheapest in

August

Average price

$382
Provider with most accurate pricing for Knoxville McGhee Tyson-New Orleans Louis Armstrong flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-New Orleans Louis Armstrong flights.
Search Deals
From Knoxville McGhee Tyson to New Orleans Louis Armstrong
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One-way flight from Knoxville McGhee Tyson to New Orleans Louis Armstrong
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($75 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to New Orleans that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 20, 2026.
Use the filters below to find and compare flights from Knoxville to New Orleans that are best for you.

Fly from

Knoxville

Fly to

New Orleans

Route

Depart

Return

Price

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Sun 3/1

9:42 pm-1:53 pm

1 stop17h 11m

New Orleans Louis Armstrong

Sat 3/7

3:37 pm-10:34 am

2 stops17h 57m

$236

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Mon 3/30

8:58 am-11:19 pm

1 stop15h 21m

New Orleans Louis Armstrong

Sat 4/4

10:30 am-5:43 pm

2 stops30h 13m

$239

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Sun 2/15

9:44 pm-3:00 pm

1 stop18h 16m

New Orleans Louis Armstrong

Thu 2/19

8:36 pm-4:59 pm

1 stop19h 23m

$252

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Sun 2/1

2:00 pm-10:20 am

1 stop21h 20m

New Orleans Louis Armstrong

Fri 2/6

6:05 am-5:28 pm

2 stops10h 23m

$274

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Wed 4/22

4:25 pm-11:08 pm

1 stop7h 43m

New Orleans Louis Armstrong

Mon 4/27

11:06 am-10:24 pm

1 stop10h 18m

$280

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Wed 3/18

8:30 am-7:01 pm

1 stop11h 31m

New Orleans Louis Armstrong

Sun 3/22

9:12 pm-2:39 pm

1 stop16h 27m

$290

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Thu 2/12

9:44 pm-2:55 pm

1 stop18h 11m

New Orleans Louis Armstrong

Sat 2/28

6:46 pm-10:07 pm

2 stops26h 21m

$298

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Mon 3/30

6:21 pm-10:38 pm

1 stop5h 17m

New Orleans Louis Armstrong

Sat 4/4

5:30 am-11:30 am

1 stop5h 00m

$299

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Mon 3/30

1:20 pm-7:50 pm

1 stop7h 30m

New Orleans Louis Armstrong

Sat 4/4

6:10 am-1:10 pm

2 stops6h 00m

$304

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Fri 4/17

6:20 pm-10:11 am

1 stop16h 51m

New Orleans Louis Armstrong

Mon 4/20

8:01 pm-9:40 am

1 stop12h 39m

$304

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/19

Showing 1-10 of 22 results
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Compare providers for flights from Knoxville to New Orleans

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to New Orleans in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
PricelinePrice Accuracy1 starTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-New Orleans flights, users find the pricing of Mytrip to be most consistent on Cheapflights vs. Mytrip Users can find the same prices on Knoxville-New Orleans flight deals on Cheapflights vs. Mytrip >95% of the time. Price accuracy is based on data collected from Knoxville-New Orleans flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-New Orleans flights, Cheapflights users trust Mytrip the most. Mytrip has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-New Orleans flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to New Orleans

Have a flexible travel schedule? Discover the best time to fly to New Orleans from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to New Orleans

How far ahead should I book a flight from Knoxville to New Orleans?

Use this chart to determine the optimal time to book a round-trip flight from Knoxville to New Orleans. Price data was last updated on January 16, 2026.

The price you pay for your flight from Knoxville to New Orleans may vary depending on when you book. For the best chance of a lower fare, look to book 57 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Knoxville to New Orleans?

Currently, August is the cheapest month in which you can book a flight from Knoxville to New Orleans (average of $130). Flying from Knoxville to New Orleans in January is currently the most expensive (average of $253). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing New Orleans

Get insights into the airlines that provide service to New Orleans. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to New Orleans. Reviews last updated January 20, 2026.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Knoxville to New Orleans. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,080 reviews

Overall

7.9

Boarding

8.1

Food

7.2

Comfort

7.9

Entertainment

7.8

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,080 reviews
Delta
7.9
Good
8,080 reviews

Overall

7.9

Boarding

8.1

Food

7.2

Comfort

7.9

Entertainment

7.8

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,183 reviews
Delta
7.9
Good
8,080 reviews

Overall

7.9

Boarding

8.1

Food

7.2

Comfort

7.9

Entertainment

7.8

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,164 reviews
Delta
7.9
Good
8,080 reviews

Overall

7.9

Boarding

8.1

Food

7.2

Comfort

7.9

Entertainment

7.8

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to New Orleans. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Knoxville to New Orleans round-trip?

    Currently priced at $228, American Airlines will fly you from Knoxville to New Orleans and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Delta and United Airlines - these airlines can fly you to your destination from $248 and $270, respectively. Users have found that American Airlines is 40% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Knoxville to New Orleans one-way?

    The cheapest airlines for a one-way flight from Knoxville to New Orleans are American Airlines ($99), Delta ($108), and United Airlines ($162).

  • Can I find deals for flights from Knoxville to New Orleans that include hotel bookings?

    Yes. In addition to deals on Knoxville to New Orleans flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to New Orleans?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to New Orleans.

  • Can I find deals for business class flights from Knoxville to New Orleans?

    Yes. Cheapflights offers flight deals from Knoxville to New Orleans by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to New Orleans?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to New Orleans (average of $130). Flying from Knoxville to New Orleans in January is currently the most expensive (average of $253). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near New Orleans?

Book flights to New Orleans if you plan to visit one of these locations
Metairie
Kenner
Slidell
Houma
Gonzales
Covington
Gretna
Thibodaux
Hammond

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Knoxville to New Orleans

Discover the top 3 airlines that operate flights from Knoxville to New Orleans. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 20, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$228Average$375FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$377FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$270Average$478FlexibilityNo cancel feeOn-time69%

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