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$119+ Cheap flights from Knoxville to New Orleans (TYS - MSY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/23. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MSY
Nov 22 — Nov 291
Sat 11/22
Sat 11/29
1 adult, Economy
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Cheapflights Tip: The best prices from Knoxville McGhee Tyson to New Orleans Louis Armstrong are usually found in August or June, booked 77 days in advance, depart on a Saturday or Friday and return on a Wednesday

Cheap flight deals from Knoxville to New Orleans

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to New Orleans (MSY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 23, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$236
(Delta)

One-way from

$119
(Kiwi.com)

Popular in

March

Cheapest in

August

Average price

$363
Provider with most accurate pricing for Knoxville McGhee Tyson-New Orleans Louis Armstrong flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-New Orleans Louis Armstrong flights.
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From Knoxville McGhee Tyson to New Orleans Louis Armstrong
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One-way flight from Knoxville McGhee Tyson to New Orleans Louis Armstrong
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Highest demand for flights based on searches. 13% potential increase in price ($55 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Knoxville to New Orleans

Cheapest flights from Knoxville to New Orleans
Explore the most affordable flight options available from Knoxville to New Orleans. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 23, 2025.

This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/25:40 amTYS - MSY
1 stop4h 59mDelta
Sat 12/61:07 pmMSY - TYS
1 stop4h 51mDelta
Deal found 10/21$236
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/309:58 amTYS - MSY
1 stop23h 09mMultiple Airlines
Wed 11/511:32 amMSY - TYS
2 stops34h 27mMultiple Airlines
Deal found 10/22$242
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/54:32 pmTYS - MSY
1 stop17h 03mMultiple Airlines
Sun 11/911:05 amMSY - TYS
2 stops33h 31mMultiple Airlines
Deal found 10/20$243
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/309:58 amTYS - MSY
1 stop23h 09mMultiple Airlines
Mon 11/38:59 pmMSY - TYS
1 stop12h 34mMultiple Airlines
Deal found 10/22$249
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/312:26 pmTYS - MSY
1 stop27h 39mMultiple Airlines
Wed 11/511:32 amMSY - TYS
2 stops34h 27mMultiple Airlines
Deal found 10/22$254
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/294:26 pmTYS - MSY
1 stop16h 41mMultiple Airlines
Wed 11/511:32 amMSY - TYS
2 stops34h 27mMultiple Airlines
Deal found 10/22$258
This Mytrip deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/65:38 pmTYS - MSY
1 stop15h 57mMultiple Airlines
Mon 11/108:59 pmMSY - TYS
1 stop12h 35mMultiple Airlines
Deal found 10/22$260
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/312:26 pmTYS - MSY
1 stop27h 39mMultiple Airlines
Mon 11/38:59 pmMSY - TYS
1 stop12h 34mMultiple Airlines
Deal found 10/22$261
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/294:26 pmTYS - MSY
1 stop16h 41mMultiple Airlines
Mon 11/38:59 pmMSY - TYS
1 stop12h 34mMultiple Airlines
Deal found 10/22$265

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to New Orleans that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 23, 2025.
Use the filters below to find and compare flights from Knoxville to New Orleans that are best for you.

Fly from

Knoxville

Fly to

New Orleans

Route

Depart

Return

Price

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Tue 12/2

5:40 am-9:39 am

1 stop4h 59m

New Orleans Louis Armstrong

Sat 12/6

1:07 pm-6:58 pm

1 stop4h 51m

$236

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Wed 11/5

4:32 pm-8:35 am

1 stop17h 03m

New Orleans Louis Armstrong

Sun 11/9

11:05 am-9:36 pm

2 stops33h 31m

$243

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Fri 2/6

5:36 pm-11:56 pm

1 stop7h 20m

New Orleans Louis Armstrong

Mon 2/9

8:00 am-4:54 pm

1 stop7h 54m

$260

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Sun 1/25

1:39 pm-7:35 am

2 stops18h 56m

New Orleans Louis Armstrong

Sun 2/1

11:07 am-11:05 pm

1 stop10h 58m

$260

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Thu 11/6

5:38 pm-8:35 am

1 stop15h 57m

New Orleans Louis Armstrong

Mon 11/10

8:59 pm-10:34 am

1 stop12h 35m

$260

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Fri 2/6

8:30 am-3:36 pm

1 stop8h 06m

New Orleans Louis Armstrong

Sun 2/8

6:11 pm-12:05 pm

2 stops16h 54m

$292

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Sun 12/21

12:21 pm-1:21 pm

1 stop26h 00m

New Orleans Louis Armstrong

Wed 12/24

6:20 am-4:41 pm

1 stop9h 21m

$293

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Thu 3/12

1:20 pm-7:50 pm

1 stop7h 30m

New Orleans Louis Armstrong

Mon 3/16

12:40 pm-6:45 pm

1 stop5h 05m

$294

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Sun 11/23

5:49 pm-7:31 am

1 stop14h 42m

$119

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Thu 11/27

5:45 am-10:14 am

1 stop5h 29m

$135

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/21

Showing 1-10 of 13 results
1
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Compare providers for flights from Knoxville to New Orleans

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to New Orleans in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-New Orleans flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-New Orleans flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-New Orleans flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-New Orleans flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-New Orleans flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to New Orleans

Have a flexible travel schedule? Discover the best time to fly to New Orleans from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to New Orleans

How far ahead should I book a flight from Knoxville to New Orleans?

Use this chart to determine the optimal time to book a round-trip flight from Knoxville to New Orleans. Price data was last updated on October 17, 2025.

The price you pay for your flight from Knoxville to New Orleans may vary depending on when you book. For the best chance of a lower fare, look to book 77 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Knoxville to New Orleans?

Currently, August is the cheapest month in which you can book a flight from Knoxville to New Orleans (average of $130). Flying from Knoxville to New Orleans in June is currently the most expensive (average of $233). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to MSY?

Find hourly flight availability from Knoxville to New Orleans. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 23, 2025.

A simple way to save on the total cost of your ticket is to fly from Knoxville to New Orleans in the afternoon. If you’re flexible enough to do this you can expect to save up to 12% on your trip compared to booking a flight in the morning.

What is the cheapest day to fly from Knoxville to New Orleans?

Use this chart to determine the cheapest time to fly round-trip from Knoxville to New Orleans. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Knoxville to New Orleans flight should consider departing on Sunday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing New Orleans

Get insights into the airlines that provide service to New Orleans. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to New Orleans. Reviews last updated October 23, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Knoxville to New Orleans. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,982 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,982 reviews
Delta
7.9
Good
7,982 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,995 reviews
Delta
7.9
Good
7,982 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,033 reviews
Delta
7.9
Good
7,982 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to New Orleans. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to New Orleans?

    Delta and American Airlines can get you from Knoxville to New Orleans in just under 4h 59m. Your travel time can differ by up to 2h 21m. Knoxville and New Orleans are separated by a distance of 541 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Knoxville to New Orleans round-trip?

    Currently priced at $223, United Airlines will fly you from Knoxville to New Orleans and back. In addition to United Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from American Airlines and Delta - these airlines can fly you to your destination from $228 and $248, respectively. Users have found that United Airlines is 38% cheaper than the other options available to this destination.

  • Can I find deals for flights from Knoxville to New Orleans that include hotel bookings?

    Yes. In addition to deals on Knoxville to New Orleans flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to New Orleans?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to New Orleans.

  • Can I find deals for business class flights from Knoxville to New Orleans?

    Yes. Cheapflights offers flight deals from Knoxville to New Orleans by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to New Orleans?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to New Orleans (average of $130). Flying from Knoxville to New Orleans in June is currently the most expensive (average of $233). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near New Orleans?

Book flights to New Orleans if you plan to visit one of these locations
Metairie
Kenner
Slidell
Houma
Covington
Gretna
Thibodaux
Hammond
Gonzales

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Top 3 airlines flying from Knoxville to New Orleans

Discover the top 3 airlines that operate flights from Knoxville to New Orleans. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$223Average$438FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$228Average$372FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$359FlexibilityNo cancel feeOn-timeN/A

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