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$116+ Cheap flights from Knoxville to New Orleans (TYS - MSY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/13. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MSY
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheapflights Tip: The best prices from Knoxville McGhee Tyson to New Orleans Louis Armstrong are usually found in August or June, booked 77 days in advance, depart on a Saturday or Friday and return on a Wednesday

Cheap flight deals from Knoxville to New Orleans

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to New Orleans (MSY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2025.

Round-trip from

$212
(Kiwi.com)

One-way from

$116
(Kiwi.com)

Popular in

March

Cheapest in

August

Average price

$387
From Knoxville McGhee Tyson to New Orleans Louis Armstrong
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One-way flight from Knoxville McGhee Tyson to New Orleans Louis Armstrong
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Highest demand for flights based on searches. 11% potential increase in price ($46 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Knoxville to New Orleans

Cheapest flights from Knoxville to New Orleans
Explore the most affordable flight options available from Knoxville to New Orleans. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/119:58 pmTYS - MSY
1 stop26h 23mMultiple Airlines
Sat 10/1810:08 pmMSY - TYS
1 stop13h 20mMultiple Airlines
Deal found 9/14$212
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:02 pmTYS - MSY
1 stop24h 38mMultiple Airlines
Thu 12/116:10 pmMSY - TYS
1 stop28h 01mMultiple Airlines
Deal found 9/14$222
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/44:47 pmTYS - MSY
1 stop22h 48mMultiple Airlines
Thu 12/116:10 pmMSY - TYS
1 stop28h 01mMultiple Airlines
Deal found 9/14$223
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/55:56 pmTYS - MSY
2 stops22h 40mMultiple Airlines
Thu 12/116:10 pmMSY - TYS
1 stop28h 01mMultiple Airlines
Deal found 9/14$225
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:02 pmTYS - MSY
1 stop24h 38mMultiple Airlines
Sun 12/146:10 pmMSY - TYS
1 stop28h 01mMultiple Airlines
Deal found 9/14$228
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/44:47 pmTYS - MSY
1 stop22h 48mMultiple Airlines
Mon 12/85:10 amMSY - TYS
2 stops17h 01mMultiple Airlines
Deal found 9/13$229
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1312:08 pmTYS - MSY
1 stop12h 45mMultiple Airlines
Mon 10/207:55 pmMSY - TYS
1 stop13h 38mMultiple Airlines
Deal found 9/15$230
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/169:25 pmTYS - MSY
1 stop19h 22mMultiple Airlines
Mon 10/207:55 pmMSY - TYS
1 stop13h 38mMultiple Airlines
Deal found 9/15$232
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/58:20 amTYS - MSY
1 stop5h 31mMultiple Airlines
Mon 12/85:10 amMSY - TYS
2 stops17h 01mMultiple Airlines
Deal found 9/13$235

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to New Orleans that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Knoxville to New Orleans that are best for you.

Fly from

Knoxville

Fly to

New Orleans

Route

Depart

Return

Price

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Thu 10/16

9:25 pm-3:47 pm

1 stop19h 22m

New Orleans Louis Armstrong

Mon 10/20

7:55 pm-10:33 am

1 stop13h 38m

$232

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Fri 10/17

7:02 pm-7:45 am

1 stop13h 43m

New Orleans Louis Armstrong

Mon 10/20

7:55 pm-10:33 am

1 stop13h 38m

$237

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Tue 10/7

2:55 pm-6:09 pm

1 stop4h 14m

New Orleans Louis Armstrong

Tue 10/14

5:20 am-9:20 am

1 stop3h 00m

$251

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Tue 11/4

8:26 am-1:13 pm

1 stop5h 47m

New Orleans Louis Armstrong

Wed 11/19

3:48 pm-11:44 pm

1 stop6h 56m

$251

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Wed 10/15

5:44 am-8:00 am

1 stop3h 16m

New Orleans Louis Armstrong

Wed 10/22

7:45 am-2:43 pm

1 stop5h 58m

$251

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Tue 10/14

7:15 am-10:48 am

1 stop4h 33m

New Orleans Louis Armstrong

Tue 10/21

2:17 pm-7:52 pm

1 stop4h 35m

$251

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Wed 12/3

5:25 am-8:13 am

1 stop3h 48m

New Orleans Louis Armstrong

Tue 12/16

3:27 pm-8:05 pm

1 stop3h 38m

$251

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Sat 12/6

8:45 am-12:01 pm

1 stop4h 16m

New Orleans Louis Armstrong

Sat 12/13

11:29 am-8:00 pm

1 stop7h 31m

$251

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Sat 12/6

8:45 am-12:01 pm

1 stop4h 16m

New Orleans Louis Armstrong

Tue 12/9

1:07 pm-6:59 pm

1 stop4h 52m

$251

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Tue 12/2

3:56 pm-8:07 pm

1 stop5h 11m

New Orleans Louis Armstrong

Sat 12/13

11:29 am-8:00 pm

1 stop7h 31m

$251

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 20 results
1
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Best time to book a flight from Knoxville to New Orleans

Have a flexible travel schedule? Discover the best time to fly to New Orleans from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to New Orleans

How far ahead should I book a flight from Knoxville to New Orleans?

Use this chart to determine the optimal time to book a round-trip flight from Knoxville to New Orleans. Price data was last updated on September 12, 2025.

The price you pay for your flight from Knoxville to New Orleans may vary depending on when you book. For the best chance of a lower fare, look to book 77 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Knoxville to New Orleans?

Currently, August is the cheapest month in which you can book a flight from Knoxville to New Orleans (average of $256). Flying from Knoxville to New Orleans in April is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to MSY?

Find hourly flight availability from Knoxville to New Orleans. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

A simple way to save on the total cost of your ticket is to fly from Knoxville to New Orleans in the afternoon. If you’re flexible enough to do this you can expect to save up to 13% on your trip compared to booking a flight in the morning.

What is the cheapest day to fly from Knoxville to New Orleans?

Use this chart to determine the cheapest time to fly round-trip from Knoxville to New Orleans. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Knoxville to New Orleans flight should consider departing on Sunday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing New Orleans

Get insights into the airlines that provide service to New Orleans. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to New Orleans. Reviews last updated September 16, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Knoxville to New Orleans. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,957 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,957 reviews
Delta
8.0
Very good
7,957 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,924 reviews
Delta
8.0
Very good
7,957 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,957 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to New Orleans. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to New Orleans?

    Delta and United Airlines can get you from Knoxville to New Orleans in just under 4h 14m. Your travel time can differ by up to 1h 33m. Knoxville and New Orleans are separated by a distance of 541 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Knoxville to New Orleans round-trip?

    Currently priced at $223, United Airlines will fly you from Knoxville to New Orleans and back. In addition to United Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from American Airlines and Delta - these airlines can fly you to your destination from $228 and $248, respectively. Users have found that United Airlines is 39% cheaper than the other options available to this destination.

  • Can I find deals for flights from Knoxville to New Orleans that include hotel bookings?

    Yes. In addition to deals on Knoxville to New Orleans flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to New Orleans?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to New Orleans.

  • Can I find deals for business class flights from Knoxville to New Orleans?

    Yes. Cheapflights offers flight deals from Knoxville to New Orleans by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to New Orleans?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to New Orleans (average of $256). Flying from Knoxville to New Orleans in April is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near New Orleans?

Book flights to New Orleans if you plan to visit one of these locations
Metairie
Kenner
Slidell
Houma
Covington
Thibodaux
Gretna
Hammond
Gonzales

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Knoxville to New Orleans

Discover the top 3 airlines that operate flights from Knoxville to New Orleans. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$223Average$438FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$228Average$393FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$361FlexibilityNo cancel feeOn-timeN/A

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