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$97+ Cheap flights from Knoxville to New Orleans (TYS - MSY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/19. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MSY
Apr 19 — Apr 261
Sun 4/19
Sun 4/26
1 adult, Economy
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Cheap flight deals from Knoxville to New Orleans

Cheapest flights from Knoxville to New Orleans
Explore the most affordable flight options available from Knoxville to New Orleans. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 20, 2026.

This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/410:00 am
TYS
-
MSY
1 stop9h 55m
Multiple Airlines
Tue 4/77:18 pm
MSY
-
TYS
1 stop14h 18m
Multiple Airlines
Deal found 3/16$206
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:39 pm
TYS
-
MSY
1 stop26h 16m
Multiple Airlines
Thu 4/236:32 pm
MSY
-
TYS
2 stops26h 16m
Multiple Airlines
Deal found 3/16$215
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/199:12 pm
TYS
-
MSY
1 stop19h 37m
Multiple Airlines
Thu 4/235:15 am
MSY
-
TYS
1 stop14h 27m
Multiple Airlines
Deal found 3/17$216
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/154:25 pm
TYS
-
MSY
1 stop8h 05m
Multiple Airlines
Wed 4/223:39 pm
MSY
-
TYS
1 stop28h 03m
Multiple Airlines
Deal found 3/18$220
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/137:30 am
TYS
-
MSY
1 stop25h 49m
Multiple Airlines
Wed 4/153:39 pm
MSY
-
TYS
1 stop22h 06m
Multiple Airlines
Deal found 3/18$227
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/2611:27 am
TYS
-
MSY
1 stop8h 51m
Multiple Airlines
Thu 4/308:15 am
MSY
-
TYS
1 stop13h 18m
Multiple Airlines
Deal found 3/20$233
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/306:20 am
TYS
-
MSY
1 stop11h 06m
Multiple Airlines
Tue 3/317:10 pm
MSY
-
TYS
1 stop14h 26m
Multiple Airlines
Deal found 3/16$237
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/2611:27 am
TYS
-
MSY
1 stop8h 51m
Multiple Airlines
Wed 4/293:39 pm
MSY
-
TYS
1 stop27h 56m
Multiple Airlines
Deal found 3/20$242
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/129:12 pm
TYS
-
MSY
1 stop19h 36m
Multiple Airlines
Sun 4/198:13 pm
MSY
-
TYS
1 stop25h 11m
Multiple Airlines
Deal found 3/15$252

Find flight deals from Knoxville to New Orleans

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to New Orleans (MSY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 20, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$206
(Kiwi.com)

One-way from

$97
(Kiwi.com)

Popular in

February

Cheapest in

August

Average price

$424
Provider with most accurate pricing for Knoxville McGhee Tyson-New Orleans Louis Armstrong flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-New Orleans Louis Armstrong flights.
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From Knoxville McGhee Tyson to New Orleans Louis Armstrong
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One-way flight from Knoxville McGhee Tyson to New Orleans Louis Armstrong
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($73 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to New Orleans that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 20, 2026.
Use the filters below to find and compare flights from Knoxville to New Orleans that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Sat 4/11

6:40 am-9:15 am

1 stop3h 35m

New Orleans Louis Armstrong

Tue 4/14

8:25 am-2:20 pm

1 stop4h 55m

$309

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Thu 5/28

8:05 am-5:25 pm

1 stop10h 20m

New Orleans Louis Armstrong

Sun 5/31

2:45 pm-9:05 pm

1 stop5h 20m

$344

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Sun 6/21

7:00 pm-12:20 am

1 stop6h 20m

New Orleans Louis Armstrong

Sat 6/27

7:00 am-2:05 pm

1 stop6h 05m

$357

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Sat 8/8

6:50 am-2:30 pm

2 stops8h 40m

New Orleans Louis Armstrong

Tue 8/11

9:45 am-6:55 pm

2 stops8h 10m

$367

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Tue 7/7

7:10 am-3:15 pm

2 stops9h 05m

New Orleans Louis Armstrong

Sun 7/12

5:40 am-3:45 pm

1 stop9h 05m

$368

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Sat 5/9

9:50 am-2:56 pm

1 stop6h 06m

New Orleans Louis Armstrong

Wed 5/13

2:15 pm-8:45 pm

1 stop5h 30m

$387

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Fri 4/24

6:35 am-2:10 pm

2 stops8h 35m

New Orleans Louis Armstrong

Sun 4/26

5:30 am-2:05 pm

2 stops7h 35m

$407
Cheapest one-way

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Wed 4/8

7:05 am-12:25 pm

2 stops6h 20m

$153

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Wed 5/13

7:05 am-12:25 pm

2 stops6h 20m

$153

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Wed 4/15

7:05 am-1:30 pm

2 stops7h 25m

$153

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/17

Showing 1-10 of 15 resultsSorted by cheapest first
1
2

Compare providers for flights from Knoxville to New Orleans

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to New Orleans in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-New Orleans flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-New Orleans flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-New Orleans flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-New Orleans flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-New Orleans flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to New Orleans

Have a flexible travel schedule? Discover the best time to fly to New Orleans from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to New Orleans

How far ahead should I book a flight from Knoxville to New Orleans?

Use this chart to determine the optimal time to book a round-trip flight from Knoxville to New Orleans. Price data was last updated on March 13, 2026.

The price you pay for your flight from Knoxville to New Orleans may vary depending on when you book. For the best chance of a lower fare, look to book 57 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Knoxville to New Orleans?

Currently, August is the cheapest month in which you can book a flight from Knoxville to New Orleans (average of $130). Flying from Knoxville to New Orleans in February is currently the most expensive (average of $269). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing New Orleans

Get insights into the airlines that provide service to New Orleans. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to New Orleans. Reviews last updated March 20, 2026.
Read reviews from past customers who have flown Southwest,Delta, andAmerican Airlines from Knoxville to New Orleans. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,325 reviews

Entertainment

7.5

Comfort

8.0

Overall

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Southwest
8.0
Very good
4,325 reviews
Southwest
8.0
Very good
4,325 reviews

Entertainment

7.5

Comfort

8.0

Overall

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Delta
7.9
Good
8,313 reviews
Southwest
8.0
Very good
4,325 reviews

Entertainment

7.5

Comfort

8.0

Overall

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
American Airlines
7.1
Good
11,488 reviews
Southwest
8.0
Very good
4,325 reviews

Entertainment

7.5

Comfort

8.0

Overall

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to New Orleans. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to New Orleans?

    Southwest can get you from Knoxville to New Orleans in just under 3h 35m. Your travel time can differ by up to . Knoxville and New Orleans are separated by a distance of 541 mi.

  • What are the cheapest airlines flying from Knoxville to New Orleans round-trip?

    Currently priced at $248, American Airlines will fly you from Knoxville to New Orleans and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Delta and Southwest - these airlines can fly you to your destination from $248 and $306, respectively. Users have found that American Airlines is 34% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Knoxville to New Orleans one-way?

    The cheapest airlines for a one-way flight from Knoxville to New Orleans are American Airlines ($99), Delta ($125), and United Airlines ($162).

  • Can I find deals for flights from Knoxville to New Orleans that include hotel bookings?

    Yes. In addition to deals on Knoxville to New Orleans flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to New Orleans?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to New Orleans.

  • Can I find deals for business class flights from Knoxville to New Orleans?

    Yes. Cheapflights offers flight deals from Knoxville to New Orleans by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to New Orleans?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to New Orleans (average of $130). Flying from Knoxville to New Orleans in February is currently the most expensive (average of $269). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near New Orleans?

Book flights to New Orleans if you plan to visit one of these locations
Metairie
Kenner
Gonzales
Houma
Slidell
Covington
Gretna
Thibodaux
Hammond

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Knoxville to New Orleans

Discover the top 3 airlines that operate flights from Knoxville to New Orleans. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 20, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$352FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$366FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$306Average$363FlexibilityNo cancel feeOn-time63%

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