What are the cheapest airlines flying from Knoxville to New Orleans round-trip?

Currently priced at $223, Delta will fly you from Knoxville to New Orleans and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from United Airlines and American Airlines - these airlines can fly you to your destination from $223 and $228, respectively. Users have found that Delta is 39% cheaper than the other options available to this destination.

In terms of precipitation, rainfall in New Orleans ranges from 3.3 - 6.4 inches per month. June is typically the wettest month, when rainfall can reach 6.4 in. October is typically the driest time to visit New Orleans when rainfall is around 3.3 in.

If weather is an important factor for your trip to New Orleans, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 82.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

What are the most popular airlines that fly from Knoxville to New Orleans?

American Airlines, Delta and United Airlines are the most popular airlines when flying from Knoxville to New Orleans.

What is the cheapest day to fly round-trip from Knoxville to New Orleans?

Flying to your destination on a Wednesday can be more expensive, but this shouldn’t discourage you from finding affordable options to get to New Orleans. Check prices with Cheapflights to find a great deal for your trip.

How far in advance should I book a flight from Knoxville to New Orleans?

When searching for a good deal, it’s best to be prepared for potential fluctuations in price. We recommend booking at least 33 days in advance, which can save you up to 42% on flights from Knoxville to New Orleans compared to booking the week you need them. Waiting 33 days out may not be for everyone, so we have options available for flights within the next two weeks, with the lowest price starting at $283. For sooner than that we have options available in the next 3 days from $338.

What is the cheapest month to fly from Knoxville to New Orleans?

The best pricing can be found in the month of August. Prices to New Orleans from Knoxville average $366. You can even find prices in August for less than $366, as users have found deals to New Orleans from as low as $218. The month of March appears to be one of the more expensive times to travel to New Orleans from Knoxville. Flying in the targeted month can save you up to 27%.

Can I find deals for flights from Knoxville to New Orleans that include hotel bookings?

Yes. In addition to deals on Knoxville to New Orleans flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Knoxville to New Orleans?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to New Orleans.

Can I find deals for business class flights from Knoxville to New Orleans?

Yes. Cheapflights offers flight deals from Knoxville to New Orleans by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$90+ Flights from Knoxville to New Orleans

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Cheapflights Tip: The best prices from Knoxville McGhee Tyson to New Orleans Louis Armstrong are usually found in August or September, booked 77 days in advance, depart on a Saturday or Friday and return on a Wednesday

Cheap flight deals from Knoxville to New Orleans

Round-trip from	$180 (Mytrip)
One-way from	$90 (Mytrip)
Popular in	March
Cheapest in	August
Average price	$273

From Knoxville McGhee Tyson to New Orleans Louis Armstrong

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One-way flight from Knoxville McGhee Tyson to New Orleans Louis Armstrong

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Highest demand for flights based on searches. 16% potential increase in price ($73 potential increase over avg. RT price).

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Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).

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Average for round-trip flights in August 2025

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Find flight deals from Knoxville to New Orleans

Cheapest flights from Knoxville to New Orleans
Explore the most affordable flight options available from Knoxville to New Orleans. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 16, 2025.

Wed 9/174:31 pmTYS - MSY

1 stop8h 21mMultiple Airlines

Wed 9/246:30 amMSY - TYS

1 stop8h 11mMultiple Airlines

Deal found 8/15

$180

Sun 9/281:20 pmTYS - MSY

1 stop11h 16mMultiple Airlines

Thu 10/24:50 pmMSY - TYS

1 stop21h 00mMultiple Airlines

Deal found 8/14

$216

Wed 9/174:31 pmTYS - MSY

1 stop8h 21mMultiple Airlines

Sun 9/218:13 pmMSY - TYS

1 stop14h 42mMultiple Airlines

Deal found 8/15

$218

Thu 9/1112:08 pmTYS - MSY

1 stop12h 44mMultiple Airlines

Thu 9/185:20 amMSY - TYS

1 stop15h 59mMultiple Airlines

Deal found 8/13

$230

Wed 9/244:31 pmTYS - MSY

1 stop8h 21mMultiple Airlines

Sun 9/289:49 pmMSY - TYS

2 stops17h 48mMultiple Airlines

Deal found 8/14

$233

Sun 10/199:01 pmTYS - MSY

1 stop12h 06mMultiple Airlines

Tue 10/218:22 pmMSY - TYS

1 stop18h 14mMultiple Airlines

Deal found 8/15

$241

Mon 9/85:27 pmTYS - MSY

1 stop7h 25mMultiple Airlines

Mon 9/156:30 amMSY - TYS

1 stop9h 07mMultiple Airlines

Deal found 8/15

$246

Best flights from Knoxville to New Orleans
Discover carefully curated flight deals from Knoxville to New Orleans that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 16, 2025.

Wed 9/174:31 pmTYS - MSY

1 stop8h 21mMultiple Airlines

Wed 9/246:30 amMSY - TYS

1 stop8h 11mMultiple Airlines

Deal found 8/15

$180

Sun 9/281:20 pmTYS - MSY

1 stop11h 16mMultiple Airlines

Thu 10/24:50 pmMSY - TYS

1 stop21h 00mMultiple Airlines

Deal found 8/14

$216

Wed 9/174:31 pmTYS - MSY

1 stop8h 21mMultiple Airlines

Sun 9/218:13 pmMSY - TYS

1 stop14h 42mMultiple Airlines

Deal found 8/15

$218

Thu 9/1112:08 pmTYS - MSY

1 stop12h 44mMultiple Airlines

Thu 9/185:20 amMSY - TYS

1 stop15h 59mMultiple Airlines

Deal found 8/13

$230

Wed 9/244:31 pmTYS - MSY

1 stop8h 21mMultiple Airlines

Sun 9/289:49 pmMSY - TYS

2 stops17h 48mMultiple Airlines

Deal found 8/14

$233

Sat 11/14:12 pmTYS - MSY

1 stop8h 41mMultiple Airlines

Fri 11/74:31 pmMSY - TYS

1 stop16h 33mMultiple Airlines

Deal found 8/15

$233

Sat 10/184:26 pmTYS - MSY

1 stop8h 27mMultiple Airlines

Tue 10/2112:20 pmMSY - TYS

1 stop25h 09mMultiple Airlines

Deal found 8/15

$233

Last-minute flights from Knoxville to New Orleans
Discover last-minute flight deals from Knoxville to New Orleans. Data last updated August 16, 2025 and is based on user searches.

Thu 8/216:14 pmTYS - MSY

1 stop6h 17mDelta

Sun 8/246:25 amMSY - TYS

1 stop3h 38mDelta

Deal found 8/15

$324

Thu 8/212:30 pmTYS - MSY

2 stops9h 58mUnited Airlines

Sun 8/245:15 pmMSY - TYS

1 stop5h 29mUnited Airlines

Deal found 8/14

$677

Fri 8/227:16 pmTYS - MSY

1 stop5h 15mDelta

Mon 8/255:03 pmMSY - TYS

1 stop5h 45mDelta

Deal found 8/15

$309

Fri 8/221:22 pmTYS - MSY

2 stops25h 48mMultiple Airlines

Mon 8/255:20 amMSY - TYS

1 stop11h 18mMultiple Airlines

Deal found 8/15

$318

Fri 8/225:45 amTYS - MSY

1 stop5h 32mUnited Airlines

Mon 8/2510:15 amMSY - TYS

2 stops9h 41mUnited Airlines

Deal found 8/15

$569

Mon 9/85:27 pmTYS - MSY

1 stop7h 25mMultiple Airlines

Mon 9/156:30 amMSY - TYS

1 stop9h 07mMultiple Airlines

Deal found 8/15

$246

Thu 9/1112:08 pmTYS - MSY

1 stop12h 44mMultiple Airlines

Thu 9/185:20 amMSY - TYS

1 stop15h 59mMultiple Airlines

Deal found 8/13

$230

Fri 9/126:08 pmTYS - MSY

1 stop6h 21mDelta

Sun 9/215:25 amMSY - TYS

1 stop4h 31mDelta

Deal found 8/15

$249

Wed 9/174:31 pmTYS - MSY

1 stop8h 21mMultiple Airlines

Wed 9/246:30 amMSY - TYS

1 stop8h 11mMultiple Airlines

Deal found 8/15

$180

Wed 9/174:31 pmTYS - MSY

1 stop8h 21mMultiple Airlines

Sun 9/218:13 pmMSY - TYS

1 stop14h 42mMultiple Airlines

Deal found 8/15

$218

Wed 9/244:31 pmTYS - MSY

1 stop8h 21mMultiple Airlines

Sun 9/289:49 pmMSY - TYS

2 stops17h 48mMultiple Airlines

Deal found 8/14

$233

Sun 9/281:20 pmTYS - MSY

1 stop11h 16mMultiple Airlines

Thu 10/24:50 pmMSY - TYS

1 stop21h 00mMultiple Airlines

Deal found 8/14

$216

One-way flights from Knoxville to New Orleans
Search for one-way flight options from Knoxville to New Orleans. Find affordable one-way fares based on user searches. Data last updated August 16, 2025.

Wed 9/174:31 pmTYS - MSY

1 stop8h 21mMultiple Airlines

Deal found 8/15

$90

Sun 9/217:35 pmTYS - MSY

2 stops24h 07mMultiple Airlines

Deal found 8/14

$107

Mon 9/14:25 pmTYS - MSY

1 stop16h 34mMultiple Airlines

Deal found 8/14

$215

Sun 12/2810:04 pmTYS - MSY

1 stop22h 39mMultiple Airlines

Deal found 8/15

$260

Sun 12/289:50 amTYS - MSY

2 stops26h 12mUnited Airlines

Deal found 8/15

$613

Cheapflights Fare Finder

Use the filters below to find and compare flights from Knoxville to New Orleans that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Wed 9/17

4:31 pm-11:52 pm

1 stop8h 21m

New Orleans Louis Armstrong

Wed 9/24

6:30 am-3:41 pm

1 stop8h 11m

$180

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Sun 9/28

1:20 pm-11:36 pm

1 stop11h 16m

New Orleans Louis Armstrong

Thu 10/2

4:50 pm-2:50 pm

1 stop21h 00m

$216

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Wed 9/17

4:31 pm-11:52 pm

1 stop8h 21m

New Orleans Louis Armstrong

Sun 9/21

8:13 pm-11:55 am

1 stop14h 42m

$218

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Thu 9/11

12:08 pm-11:52 pm

1 stop12h 44m

New Orleans Louis Armstrong

Thu 9/18

5:20 am-10:19 pm

1 stop15h 59m

$230

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Wed 9/24

4:31 pm-11:52 pm

1 stop8h 21m

New Orleans Louis Armstrong

Sun 9/28

9:49 pm-4:37 pm

2 stops17h 48m

$233

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Sat 11/1

4:12 pm-11:53 pm

1 stop8h 41m

New Orleans Louis Armstrong

Fri 11/7

4:31 pm-10:04 am

1 stop16h 33m

$233

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Sat 10/18

4:26 pm-11:53 pm

1 stop8h 27m

New Orleans Louis Armstrong

Tue 10/21

12:20 pm-2:29 pm

1 stop25h 09m

$233

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Wed 9/17

4:31 pm-11:52 pm

1 stop8h 21m

$90

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Sun 9/21

7:35 pm-6:42 pm

2 stops24h 07m

$107

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Mon 9/1

4:25 pm-7:59 am

1 stop16h 34m

$215

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/15

Showing 1-10 of 12 results

Best time to book a flight from Knoxville to New Orleans

Have a flexible travel schedule? Discover the best time to fly to New Orleans from Knoxville with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to New Orleans

How far ahead should I book a flight from Knoxville to New Orleans?

The price you pay for your flight from Knoxville to New Orleans may vary depending on when you book. For the best chance of a lower fare, look to book 77 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Knoxville to New Orleans?

Currently, August is the cheapest month in which you can book a flight from Knoxville to New Orleans (average of $256). Flying from Knoxville to New Orleans in April is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to MSY?

A simple way to save on the total cost of your ticket is to fly from Knoxville to New Orleans in the afternoon. If you’re flexible enough to do this you can expect to save up to 13% on your trip compared to booking a flight in the morning.

What is the cheapest day to fly from Knoxville to New Orleans?

Travelers seeking maximum savings on their Knoxville to New Orleans flight should consider departing on Sunday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing New Orleans

Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Knoxville to New Orleans. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,985 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,985 reviews

Delta

8.0

Very good

7,985 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

United Airlines

7.4

Good

8,916 reviews

Delta

8.0

Very good

7,985 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,985 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What are the cheapest airlines flying from Knoxville to New Orleans round-trip?
Currently priced at $223, Delta will fly you from Knoxville to New Orleans and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from United Airlines and American Airlines - these airlines can fly you to your destination from $223 and $228, respectively. Users have found that Delta is 39% cheaper than the other options available to this destination.
Can I find deals for flights from Knoxville to New Orleans that include hotel bookings?
Yes. In addition to deals on Knoxville to New Orleans flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Knoxville to New Orleans?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to New Orleans.
Can I find deals for business class flights from Knoxville to New Orleans?
Yes. Cheapflights offers flight deals from Knoxville to New Orleans by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Knoxville to New Orleans?
Currently, August is the cheapest month in which you can book a flight from Knoxville to New Orleans (average of $256). Flying from Knoxville to New Orleans in April is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Metairie

Kenner

Slidell

Houma

Covington

Thibodaux

Gretna

Hammond

Gonzales

Browse thousands of different options on Cheapflights for your next trip

Top 3 airlines flying from Knoxville to New Orleans

Airline	Cheapest	Average	Flexibility	On-time
United Airlines	Cheapest$223	Average$373	FlexibilityNo cancel fee	On-time69%
Delta	Cheapest$223	Average$357	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$228	Average$394	FlexibilityNo cancel fee	On-time71%

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$90+ Cheap flights from Knoxville to New Orleans (TYS - MSY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/17. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Knoxville to New Orleans with Cheapflights

1. Tell us where you want to go

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3. Compare prices and book

Cheapflights Tip: The best prices from Knoxville McGhee Tyson to New Orleans Louis Armstrong are usually found in August or September, booked 77 days in advance, depart on a Saturday or Friday and return on a Wednesday

Cheap flight deals from Knoxville to New Orleans

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Knoxville to New Orleans

Cheapest flights from Knoxville to New OrleansExplore the most affordable flight options available from Knoxville to New Orleans. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 16, 2025.

Explore the most affordable flight options available from Knoxville to New Orleans. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 16, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Knoxville to New Orleans that are best for you.

Best time to book a flight from Knoxville to New Orleans

Have a flexible travel schedule? Discover the best time to fly to New Orleans from Knoxville with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to New Orleans

How far ahead should I book a flight from Knoxville to New Orleans?

Use this chart to determine the optimal time to book a round-trip flight from Knoxville to New Orleans. Price data was last updated on August 8, 2025.

What is the cheapest month to book a flight from Knoxville to New Orleans?

What is the cheapest time of day to fly from TYS to MSY?

Find hourly flight availability from Knoxville to New Orleans. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 16, 2025.

What is the cheapest day to fly from Knoxville to New Orleans?

Use this chart to determine the cheapest time to fly round-trip from Knoxville to New Orleans. Price data was last updated on December 16, 2024.

Reviews of airlines servicing New Orleans

Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Knoxville to New Orleans. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to New Orleans. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Knoxville to New Orleans round-trip?

Can I find deals for flights from Knoxville to New Orleans that include hotel bookings?

How can I find direct flights from Knoxville to New Orleans?

Can I find deals for business class flights from Knoxville to New Orleans?

What is the cheapest month to book a flight from Knoxville to New Orleans?

Traveling to a place near New Orleans?

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Alternative routes for Knoxville to New Orleans

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Top 3 airlines flying from Knoxville to New Orleans

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Cheapest flights from Knoxville to New Orleans
Explore the most affordable flight options available from Knoxville to New Orleans. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 16, 2025.