$109+ Cheap flights from Missouri to Myrtle Beach (MYR)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/9. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MYR
Jun 11 — Jun 181
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Missouri to Myrtle BeachExplore the most affordable flight options available from Missouri to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 12, 2026.
Explore the most affordable flight options available from Missouri to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 12, 2026.
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:10 am
SGF
- MYR
1 stop4h 14m
American Airlines
Sat 9/512:08 pm
MYR
- SGF
1 stop8h 05m
American Airlines
Deal found 5/11![American Airlines logo]()
$285
This American Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:11 pm
STL
- MYR
1 stop5h 59m
American Airlines
Thu 6/46:45 pm
MYR
- STL
1 stop6h 14m
American Airlines
Deal found 5/8![American Airlines logo]()
$291
This Southwest deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/910:45 am
STL
- MYR
2 stops7h 25m
Southwest
Wed 9/167:50 am
MYR
- STL
1 stop4h 30m
Southwest
Deal found 5/9![Southwest logo]()
$296
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/97:09 pm
MCI
- MYR
1 stop17h 57m
Multiple Airlines
Mon 8/173:31 pm
MYR
- MCI
2 stops50h 53m
Multiple Airlines
Deal found 5/11![Multiple Airlines logo]()
$314
This Southwest deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/12:05 pm
STL
- MYR
1 stop5h 10m
Southwest
Wed 10/78:20 am
MYR
- STL
2 stops7h 50m
Southwest
Deal found 5/12![Southwest logo]()
$318
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/244:17 pm
STL
- MYR
1 stop16h 33m
Multiple Airlines
Wed 7/83:17 pm
MYR
- STL
2 stops27h 20m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$322
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:12 pm
STL
- MYR
1 stop4h 37m
American Airlines
Mon 6/88:41 pm
MYR
- STL
1 stop4h 03m
American Airlines
Deal found 5/11![American Airlines logo]()
$323
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/97:03 am
STL
- MYR
2 stops7h 29m
American Airlines
Sat 6/136:12 pm
MYR
- STL
2 stops7h 04m
American Airlines
Deal found 5/11![American Airlines logo]()
$334
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:57 pm
MCI
- MYR
1 stop18h 09m
Multiple Airlines
Thu 7/234:04 pm
MYR
- MCI
2 stops26h 17m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$338
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:06 pm
STL
- MYR
2 stops26h 57m
Multiple Airlines
Wed 7/82:42 pm
MYR
- STL
1 stop10h 17m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:57 pm
SGF
- MYR
1 stop4h 02m
Delta
Wed 6/174:17 pm
MYR
- SGF
1 stop6h 52m
Delta
Deal found 5/11![Delta logo]()
$352
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/116:16 pm
MCI
- MYR
2 stops41h 14m
Multiple Airlines
Thu 7/239:07 pm
MYR
- MCI
1 stop13h 43m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$354
Best flights from Missouri to Myrtle BeachDiscover carefully curated flight deals from Missouri to Myrtle Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 12, 2026.
Discover carefully curated flight deals from Missouri to Myrtle Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 12, 2026.
This Southwest deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/232:30 pm
STL
- MYR
1 stop5h 50m
Southwest
Mon 7/277:15 pm
MYR
- STL
1 stop4h 35m
Southwest
Deal found 5/11![Southwest logo]()
$355
This Delta deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2511:38 am
SGF
- MYR
1 stop5h 29m
Delta
Sun 8/307:04 pm
MYR
- SGF
1 stop4h 17m
Delta
Deal found 5/12![Delta logo]()
$357
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:42 am
STL
- MYR
1 stop7h 55m
American Airlines
Thu 9/34:20 pm
MYR
- STL
1 stop4h 22m
American Airlines
Deal found 5/7![American Airlines logo]()
$364
This United Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:00 am
STL
- MYR
1 stop5h 17m
United Airlines
Wed 8/266:59 pm
MYR
- STL
1 stop5h 39m
United Airlines
Deal found 5/11![United Airlines logo]()
$381
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:05 pm
STL
- MYR
2 stops6h 20m
Southwest
Tue 10/62:35 pm
MYR
- STL
2 stops6h 00m
Southwest
Deal found 5/8![Southwest logo]()
$366
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/307:05 pm
STL
- MYR
1 stop3h 53m
Delta
Thu 6/46:00 am
MYR
- STL
1 stop4h 44m
Delta
Deal found 5/10![Delta logo]()
$397
This American Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:00 am
SGF
- MYR
2 stops8h 30m
American Airlines
Sat 9/125:33 am
MYR
- SGF
1 stop5h 53m
American Airlines
Deal found 5/8![American Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:00 am
STL
- MYR
1 stop7h 12m
United Airlines
Wed 6/106:50 pm
MYR
- STL
1 stop5h 45m
United Airlines
Deal found 5/7![United Airlines logo]()
$403
This Southwest deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/69:30 am
STL
- MYR
1 stop5h 40m
Southwest
Sat 6/65:45 pm
MYR
- STL
1 stop6h 25m
Southwest
Deal found 5/12![Southwest logo]()
$371
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/2510:32 am
COU
- MYR
2 stops8h 31m
American Airlines
Wed 7/296:10 pm
MYR
- COU
1 stop5h 36m
American Airlines
Deal found 5/7![American Airlines logo]()
$410
This Southwest deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/157:50 am
STL
- MYR
1 stop3h 55m
Southwest
Fri 8/211:55 pm
MYR
- STL
Nonstop2h 05m
Southwest
Deal found 5/9![Southwest logo]()
$374
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/305:38 am
MCI
- MYR
1 stop4h 06m
Delta
Sun 7/56:00 am
MYR
- MCI
1 stop4h 31m
Delta
Deal found 5/9![Delta logo]()
$412
This United Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:53 am
MCI
- MYR
1 stop5h 09m
United Airlines
Wed 6/310:34 am
MYR
- MCI
2 stops12h 57m
United Airlines
Deal found 5/7![United Airlines logo]()
$454
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:14 am
SGF
- MYR
1 stop6h 32m
American Airlines
Wed 6/36:06 pm
MYR
- SGF
1 stop4h 35m
American Airlines
Deal found 5/11![American Airlines logo]()
$417
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/145:19 pm
MCI
- MYR
1 stop5h 11m
Delta
Sat 8/226:00 am
MYR
- MCI
1 stop5h 15m
Delta
Deal found 5/11![Delta logo]()
$424
This Southwest deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/234:00 pm
STL
- MYR
1 stop4h 45m
Southwest
Sun 6/285:45 pm
MYR
- STL
1 stop7h 25m
Southwest
Deal found 5/9![Southwest logo]()
$396
This Delta deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:26 pm
MCI
- MYR
1 stop5h 09m
Delta
Mon 10/126:45 pm
MYR
- MCI
1 stop6h 13m
Delta
Deal found 5/7![Delta logo]()
$429
This Southwest deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/203:35 pm
STL
- MYR
1 stop6h 10m
Southwest
Fri 7/247:15 pm
MYR
- STL
1 stop4h 35m
Southwest
Deal found 5/9![Southwest logo]()
$396
This American Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/81:27 pm
SGF
- MYR
1 stop7h 19m
American Airlines
Mon 6/154:17 pm
MYR
- SGF
1 stop6h 24m
American Airlines
Deal found 5/9![American Airlines logo]()
$469
This Southwest deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/259:55 am
STL
- MYR
2 stops7h 40m
Southwest
Tue 7/212:10 pm
MYR
- STL
1 stop6h 05m
Southwest
Deal found 5/10![Southwest logo]()
$400
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1711:32 am
SGF
- MYR
1 stop6h 35m
Delta
Mon 7/201:51 pm
MYR
- SGF
1 stop5h 17m
Delta
Deal found 5/9![Delta logo]()
$474
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/14:00 pm
STL
- MYR
1 stop4h 45m
Southwest
Sat 7/47:15 am
MYR
- STL
Nonstop2h 05m
Southwest
Deal found 5/8![Southwest logo]()
$406
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:19 pm
COU
- MYR
1 stop5h 32m
American Airlines
Sat 5/306:33 am
MYR
- COU
1 stop5h 41m
American Airlines
Deal found 5/11![American Airlines logo]()
$542
This Southwest deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/25:15 am
MCI
- MYR
1 stop5h 00m
Southwest
Tue 7/77:15 pm
MYR
- MCI
1 stop5h 10m
Southwest
Deal found 5/10![Southwest logo]()
$412
This United Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/258:00 am
COU
- MYR
1 stop5h 19m
United Airlines
Wed 7/293:15 pm
MYR
- COU
1 stop9h 18m
United Airlines
Deal found 5/9![United Airlines logo]()
$737
This Southwest deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1610:15 am
MCI
- MYR
2 stops9h 55m
Southwest
Thu 6/187:25 am
MYR
- MCI
2 stops6h 45m
Southwest
Deal found 5/11![Southwest logo]()
$422
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:10 am
MCI
- MYR
2 stops7h 00m
Southwest
Tue 8/2511:00 am
MYR
- MCI
2 stops7h 35m
Southwest
Deal found 5/8![Southwest logo]()
$422
This American Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:45 am
SGF
- MYR
2 stops8h 59m
American Airlines
Mon 10/129:06 am
MYR
- SGF
1 stop4h 36m
American Airlines
Deal found 5/8![American Airlines logo]()
$620
This United Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:35 pm
SGF
- MYR
2 stops14h 24m
United Airlines
Sat 5/3010:34 am
MYR
- SGF
2 stops8h 26m
United Airlines
Deal found 5/11![United Airlines logo]()
$795
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/26:53 pm
SGF
- MYR
1 stop4h 02m
Delta
Wed 8/57:04 pm
MYR
- SGF
1 stop4h 17m
Delta
Deal found 5/8![Delta logo]()
$675
Last-minute flights from Missouri to Myrtle BeachDiscover last-minute flight deals from Missouri to Myrtle Beach. Data last updated May 12, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Myrtle Beach. Data last updated May 12, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/175:35 am
MCI
- MYR
1 stop5h 29m
American Airlines
Wed 5/209:14 am
MYR
- MCI
1 stop5h 02m
American Airlines
Deal found 5/11![American Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/299:13 am
STL
- MYR
1 stop5h 08m
Delta
Thu 6/47:55 pm
MYR
- STL
1 stop5h 04m
Delta
Deal found 5/11![Delta logo]()
$365
This American Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:11 pm
STL
- MYR
1 stop5h 59m
American Airlines
Thu 6/46:45 pm
MYR
- STL
1 stop6h 14m
American Airlines
Deal found 5/8![American Airlines logo]()
$291
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/33:30 pm
MCI
- MYR
1 stop6h 10m
Southwest
Sat 6/64:35 pm
MYR
- MCI
1 stop6h 20m
Southwest
Deal found 5/8![Southwest logo]()
$376
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/51:48 pm
MCI
- MYR
2 stops6h 58m
American Airlines
Fri 6/124:17 pm
MYR
- MCI
2 stops9h 08m
American Airlines
Deal found 5/12![American Airlines logo]()
$380
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:12 pm
STL
- MYR
1 stop4h 37m
American Airlines
Mon 6/88:41 pm
MYR
- STL
1 stop4h 03m
American Airlines
Deal found 5/11![American Airlines logo]()
$323
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/97:03 am
STL
- MYR
2 stops7h 29m
American Airlines
Sat 6/136:12 pm
MYR
- STL
2 stops7h 04m
American Airlines
Deal found 5/11![American Airlines logo]()
$334
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:57 pm
SGF
- MYR
1 stop4h 02m
Delta
Wed 6/174:17 pm
MYR
- SGF
1 stop6h 52m
Delta
Deal found 5/11![Delta logo]()
$352
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/244:17 pm
STL
- MYR
1 stop16h 33m
Multiple Airlines
Wed 7/83:17 pm
MYR
- STL
2 stops27h 20m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$322
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/243:10 pm
STL
- MYR
1 stop4h 20m
Southwest
Mon 6/2910:35 am
MYR
- STL
1 stop4h 45m
Southwest
Deal found 5/8![Southwest logo]()
$355
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/276:12 pm
STL
- MYR
1 stop4h 37m
American Airlines
Thu 7/26:10 pm
MYR
- STL
2 stops7h 06m
American Airlines
Deal found 5/12![American Airlines logo]()
$360
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/284:17 pm
STL
- MYR
1 stop15h 48m
Multiple Airlines
Wed 7/13:17 pm
MYR
- STL
2 stops27h 13m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$361
One-way flights from Missouri to Myrtle BeachSearch for one-way flight options from Missouri to Myrtle Beach. Find affordable one-way fares based on user searches. Data last updated May 12, 2026.
Search for one-way flight options from Missouri to Myrtle Beach. Find affordable one-way fares based on user searches. Data last updated May 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/96:33 pm
STL
- MYR
2 stops19h 49m
Multiple Airlines
Deal found 5/11![Multiple Airlines logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/316:16 pm
MCI
- MYR
2 stops25h 52m
Multiple Airlines
Deal found 5/8![Multiple Airlines logo]()
$110
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/55:27 pm
STL
- MYR
2 stops26h 42m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/26:31 pm
STL
- MYR
2 stops36h 30m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$113
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:16 pm
MCI
- MYR
2 stops25h 47m
Multiple Airlines
Deal found 5/7![Multiple Airlines logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:06 pm
STL
- MYR
2 stops26h 57m
Multiple Airlines
Deal found 5/7![Multiple Airlines logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:24 pm
MCI
- MYR
2 stops25h 45m
Multiple Airlines
Deal found 5/12![Multiple Airlines logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/76:33 pm
STL
- MYR
2 stops20h 07m
Multiple Airlines
Deal found 5/11![Multiple Airlines logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:33 pm
STL
- MYR
2 stops19h 49m
Multiple Airlines
Deal found 5/11![Multiple Airlines logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/106:16 pm
MCI
- MYR
2 stops25h 47m
Multiple Airlines
Deal found 5/12![Multiple Airlines logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:33 pm
STL
- MYR
2 stops38h 29m
Multiple Airlines
Deal found 5/11![Multiple Airlines logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/286:31 pm
STL
- MYR
2 stops20h 04m
Multiple Airlines
Deal found 5/8![Multiple Airlines logo]()
$130
Find flight deals from Missouri to Myrtle Beach
Keep the following information in mind while searching for Missouri to Myrtle Beach flight deals. Data was last updated May 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $285 (American Airlines) |
One-way from | $109 (Kiwi.com) |
Popular in | April |
Cheapest in | February |
Average price | $365 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Myrtle Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 12, 2026.
Use the filters below to find and compare flights from Missouri to Myrtle Beach that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisMyrtle Beach
STL - MYR
STLMYR
Lambert-St Louis
Thu 7/23
2:30 pm-9:20 pm
1 stop5h 50m
Myrtle Beach Intl
Mon 7/27
7:15 pm-10:50 pm
1 stop4h 35m
$355
SpringfieldMyrtle Beach
SGF - MYR
SGFMYR
Springfield-Branson
Tue 8/25
11:38 am-6:07 pm
1 stop5h 29m
Myrtle Beach Intl
Sun 8/30
7:04 pm-10:21 pm
1 stop4h 17m
$357
St. LouisMyrtle Beach
STL - MYR
STLMYR
Lambert-St Louis
Fri 8/28
6:42 am-3:37 pm
1 stop7h 55m
Myrtle Beach Intl
Thu 9/3
4:20 pm-7:42 pm
1 stop4h 22m
$364
St. LouisMyrtle Beach
STL - MYR
STLMYR
Lambert-St Louis
Sat 10/3
12:05 pm-7:25 pm
2 stops6h 20m
Myrtle Beach Intl
Tue 10/6
2:35 pm-7:35 pm
2 stops6h 00m
$366
St. LouisMyrtle Beach
STL - MYR
STLMYR
Lambert-St Louis
Sat 6/6
9:30 am-4:10 pm
1 stop5h 40m
Myrtle Beach Intl
Sat 6/6
5:45 pm-11:10 pm
1 stop6h 25m
$371
Quickest round-trip
St. LouisMyrtle Beach
STL - MYR
STLMYR
Lambert-St Louis
Sat 8/15
7:50 am-12:45 pm
1 stop3h 55m
Myrtle Beach Intl
Fri 8/21
1:55 pm-3:00 pm
Nonstop2h 05m
$374
St. LouisMyrtle Beach
STL - MYR
STLMYR
Lambert-St Louis
Tue 8/25
8:00 am-2:17 pm
1 stop5h 17m
Myrtle Beach Intl
Wed 8/26
6:59 pm-11:38 pm
1 stop5h 39m
$381
St. LouisMyrtle Beach
STL - MYR
STLMYR
Lambert-St Louis
Tue 6/23
4:00 pm-9:45 pm
1 stop4h 45m
Myrtle Beach Intl
Sun 6/28
5:45 pm-12:10 am
1 stop7h 25m
$396
St. LouisMyrtle Beach
STL - MYR
STLMYR
Lambert-St Louis
Mon 7/20
3:35 pm-10:45 pm
1 stop6h 10m
Myrtle Beach Intl
Fri 7/24
7:15 pm-10:50 pm
1 stop4h 35m
$396
St. LouisMyrtle Beach
STL - MYR
STLMYR
Lambert-St Louis
Sat 5/30
7:05 pm-11:58 pm
1 stop3h 53m
Myrtle Beach Intl
Thu 6/4
6:00 am-9:44 am
1 stop4h 44m
$397
Showing 1-10 of 57 resultsSorted by cheapest first
Best time to book a flight from Missouri to Myrtle Beach
Have a flexible travel schedule? Discover the best time to fly to Myrtle Beach from Missouri with our price prediction graph.
STL-MYR
MCI-MYR
COU-MYR
SGF-MYR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Myrtle Beach
USMO-MYR
STL-MYR
MCI-MYR
COU-MYR
SGF-MYR
How far ahead should I book a flight from Missouri to Myrtle Beach?
The best time to book flights from Missouri to Myrtle Beach is 82 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Missouri to Myrtle Beach?
Currently, July is the cheapest month in which you can book a flight from Missouri to Myrtle Beach (average of $98). Flying from Missouri to Myrtle Beach in December is currently the most expensive (average of $300). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to MYR?
Find hourly flight availability from Missouri to Myrtle Beach. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 12, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Myrtle Beach as you normally would.
How much does it cost to fly round-trip from Missouri to Myrtle Beach?
Related info for your journey
Find useful and relevant information for your journey from Missouri to Myrtle Beach. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Myrtle Beach?
Book flights to Myrtle Beach if you plan to visit one of these locationsConway
Surfside Beach
Pawleys Island
Little River
Garden City Beach
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Complete your trip
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Other flights to Myrtle Beach
Explore flights to Myrtle Beach departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 12, 2026.
Missouri and Myrtle Beach flights
Browse other Missouri and Myrtle Beach flight options. Last updated on May 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Missouri to Myrtle Beach flights
Consider these flights traveling from Missouri to Myrtle Beach.
Top 5 airlines flying from Missouri to Myrtle Beach
Discover the top 5 airlines that operate flights from Missouri to Myrtle Beach. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$99 | Average$366 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$176 | Average$218 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$193 | Average$419 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$196 | Average$338 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$257 | Average$407 | FlexibilityNo cancel fee | On-time63% |