$89+ Cheap flights from Missouri to Myrtle Beach (MYR)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/25. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MYR
Aug 22 — Aug 291
Round-trip
1 adult, Economy
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Find cheap flights from Missouri to Myrtle Beach with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Missouri to Myrtle BeachExplore the most affordable flight options available from Missouri to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 23, 2026.
Explore the most affordable flight options available from Missouri to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 23, 2026.
This Delta deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:18 pm
MCI
- MYR
1 stop5h 12m
Delta
Mon 8/247:02 pm
MYR
- MCI
1 stop5h 56m
Delta
Deal found 7/19![Delta logo]()
$257
This Southwest deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2510:20 am
MCI
- MYR
2 stops8h 00m
Southwest
Sat 8/299:55 am
MYR
- MCI
1 stop6h 15m
Southwest
Deal found 7/20![Southwest logo]()
$262
This Delta deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/287:00 am
MCI
- MYR
1 stop5h 00m
Delta
Wed 8/126:00 am
MYR
- MCI
1 stop4h 19m
Delta
Deal found 7/18![Delta logo]()
$265
This Southwest deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/121:25 pm
MCI
- MYR
1 stop4h 55m
Southwest
Sat 8/229:55 am
MYR
- MCI
1 stop8h 20m
Southwest
Deal found 7/22![Southwest logo]()
$267
This Southwest deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2310:15 am
MCI
- MYR
2 stops10h 10m
Southwest
Mon 10/266:40 am
MYR
- MCI
1 stop7h 35m
Southwest
Deal found 7/20![Southwest logo]()
$268
This Southwest deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/269:20 am
MCI
- MYR
2 stops8h 50m
Southwest
Wed 9/22:25 pm
MYR
- MCI
1 stop6h 45m
Southwest
Deal found 7/22![Southwest logo]()
$272
This Southwest deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/273:00 pm
MCI
- MYR
1 stop5h 25m
Southwest
Thu 7/309:10 pm
MYR
- MCI
1 stop4h 05m
Southwest
Deal found 7/20![Southwest logo]()
$273
This American Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/141:04 pm
MCI
- MYR
1 stop6h 55m
American Airlines
Fri 8/218:08 am
MYR
- MCI
1 stop5h 06m
American Airlines
Deal found 7/18![American Airlines logo]()
$274
This Delta deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/312:22 pm
MCI
- MYR
1 stop4h 45m
Delta
Sun 8/167:02 pm
MYR
- MCI
1 stop5h 56m
Delta
Deal found 7/21![Delta logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:02 pm
STL
- MYR
1 stop14h 53m
Multiple Airlines
Thu 9/108:27 am
MYR
- STL
2 stops50h 13m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$279
This Delta deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:39 am
MCI
- MYR
1 stop4h 08m
Delta
Tue 8/47:02 pm
MYR
- MCI
1 stop5h 56m
Delta
Deal found 7/21![Delta logo]()
$283
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/154:32 pm
MCI
- MYR
1 stop5h 45m
American Airlines
Tue 8/254:23 pm
MYR
- MCI
1 stop7h 27m
American Airlines
Deal found 7/21![American Airlines logo]()
$285
Best flights from Missouri to Myrtle BeachDiscover carefully curated flight deals from Missouri to Myrtle Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 23, 2026.
Discover carefully curated flight deals from Missouri to Myrtle Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 23, 2026.
This Delta deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:18 pm
MCI
- MYR
1 stop5h 12m
Delta
Mon 8/247:02 pm
MYR
- MCI
1 stop5h 56m
Delta
Deal found 7/19![Delta logo]()
$257
This Southwest deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/162:00 pm
MCI
- MYR
1 stop6h 25m
Southwest
Sun 8/236:50 pm
MYR
- MCI
1 stop5h 55m
Southwest
Deal found 7/19![Southwest logo]()
$257
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/611:27 am
SGF
- MYR
1 stop5h 15m
American Airlines
Sat 9/1212:10 pm
MYR
- SGF
2 stops8h 08m
American Airlines
Deal found 7/23![American Airlines logo]()
$354
This United Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/128:00 am
COU
- MYR
1 stop5h 33m
United Airlines
Tue 12/1511:25 am
MYR
- COU
1 stop6h 58m
United Airlines
Deal found 7/18![United Airlines logo]()
$378
This Delta deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:00 am
MCI
- MYR
1 stop6h 56m
Delta
Fri 10/236:00 am
MYR
- MCI
1 stop7h 27m
Delta
Deal found 7/20![Delta logo]()
$257
This Southwest deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/141:40 pm
MCI
- MYR
1 stop4h 40m
Southwest
Fri 8/212:30 pm
MYR
- MCI
2 stops8h 20m
Southwest
Deal found 7/18![Southwest logo]()
$293
This Delta deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/312:22 pm
MCI
- MYR
1 stop4h 45m
Delta
Tue 8/47:02 pm
MYR
- MCI
1 stop5h 56m
Delta
Deal found 7/21![Delta logo]()
$283
This Southwest deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/145:10 am
MCI
- MYR
2 stops8h 35m
Southwest
Mon 9/212:30 pm
MYR
- MCI
1 stop9h 05m
Southwest
Deal found 7/18![Southwest logo]()
$299
This Delta deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/54:00 pm
SGF
- MYR
1 stop4h 49m
Delta
Thu 9/105:45 pm
MYR
- SGF
1 stop5h 23m
Delta
Deal found 7/20![Delta logo]()
$285
This Southwest deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:40 am
STL
- MYR
1 stop7h 00m
Southwest
Mon 9/282:30 pm
MYR
- STL
1 stop5h 40m
Southwest
Deal found 7/20![Southwest logo]()
$315
This Delta deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:43 am
MCI
- MYR
1 stop4h 04m
Delta
Mon 8/176:00 am
MYR
- MCI
1 stop4h 19m
Delta
Deal found 7/20![Delta logo]()
$288
This Delta deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/94:00 pm
SGF
- MYR
1 stop4h 41m
Delta
Thu 9/105:45 pm
MYR
- SGF
1 stop5h 23m
Delta
Deal found 7/21![Delta logo]()
$295
This Southwest deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/711:40 am
STL
- MYR
1 stop7h 00m
Southwest
Fri 9/111:55 pm
MYR
- STL
Nonstop2h 05m
Southwest
Deal found 7/21![Southwest logo]()
$325
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/128:00 am
SGF
- MYR
1 stop5h 33m
United Airlines
Tue 12/153:20 pm
MYR
- SGF
1 stop7h 03m
United Airlines
Deal found 7/20![United Airlines logo]()
$477
This Southwest deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/178:25 am
MCI
- MYR
2 stops5h 20m
Southwest
Mon 8/242:30 pm
MYR
- MCI
2 stops8h 20m
Southwest
Deal found 7/20![Southwest logo]()
$329
This Delta deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/264:00 pm
SGF
- MYR
1 stop4h 41m
Delta
Sat 10/36:00 am
MYR
- SGF
1 stop6h 21m
Delta
Deal found 7/20![Delta logo]()
$312
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:15 am
COU
- MYR
1 stop7h 02m
United Airlines
Wed 9/910:10 am
MYR
- COU
2 stops11h 49m
United Airlines
Deal found 7/20![United Airlines logo]()
$480
This Southwest deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:35 am
STL
- MYR
2 stops6h 30m
Southwest
Wed 8/262:25 pm
MYR
- STL
2 stops8h 15m
Southwest
Deal found 7/22![Southwest logo]()
$335
This Delta deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/81:53 pm
MCI
- MYR
1 stop6h 56m
Delta
Tue 8/117:02 pm
MYR
- MCI
1 stop5h 56m
Delta
Deal found 7/20![Delta logo]()
$318
This Southwest deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/298:30 am
STL
- MYR
2 stops9h 30m
Southwest
Tue 9/18:15 am
MYR
- STL
2 stops7h 55m
Southwest
Deal found 7/21![Southwest logo]()
$345
This United Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2111:17 am
COU
- MYR
2 stops22h 51m
United Airlines
Tue 9/2910:23 am
MYR
- COU
2 stops11h 10m
United Airlines
Deal found 7/19![United Airlines logo]()
$543
This Delta deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/114:00 pm
SGF
- MYR
1 stop4h 41m
Delta
Mon 9/146:56 pm
MYR
- SGF
1 stop4h 12m
Delta
Deal found 7/18![Delta logo]()
$357
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/76:15 am
COU
- MYR
1 stop7h 38m
United Airlines
Fri 9/1110:08 am
MYR
- COU
2 stops11h 51m
United Airlines
Deal found 7/20![United Airlines logo]()
$552
This Southwest deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1811:05 am
STL
- MYR
2 stops7h 35m
Southwest
Mon 9/212:30 pm
MYR
- STL
1 stop5h 40m
Southwest
Deal found 7/20![Southwest logo]()
$381
This Delta deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/64:00 pm
SGF
- MYR
1 stop4h 49m
Delta
Sat 9/126:00 am
MYR
- SGF
1 stop6h 21m
Delta
Deal found 7/19![Delta logo]()
$362
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/76:15 am
COU
- MYR
1 stop7h 38m
United Airlines
Wed 9/910:10 am
MYR
- COU
2 stops11h 49m
United Airlines
Deal found 7/20![United Airlines logo]()
$552
This Southwest deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:05 am
STL
- MYR
1 stop6h 45m
Southwest
Sun 8/302:45 pm
MYR
- STL
Nonstop2h 05m
Southwest
Deal found 7/18![Southwest logo]()
$386
This Delta deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/912:00 pm
STL
- MYR
1 stop5h 03m
Delta
Wed 10/1410:54 am
MYR
- STL
1 stop6h 29m
Delta
Deal found 7/19![Delta logo]()
$376
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:15 am
COU
- MYR
1 stop7h 02m
United Airlines
Fri 9/1110:08 am
MYR
- COU
2 stops25h 30m
United Airlines
Deal found 7/21![United Airlines logo]()
$554
This Southwest deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:00 am
STL
- MYR
2 stops9h 20m
Southwest
Fri 11/138:45 pm
MYR
- STL
1 stop4h 10m
Southwest
Deal found 7/18![Southwest logo]()
$391
Last-minute flights from Missouri to Myrtle BeachDiscover last-minute flight deals from Missouri to Myrtle Beach. Data last updated July 23, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Myrtle Beach. Data last updated July 23, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/273:00 pm
MCI
- MYR
1 stop5h 25m
Southwest
Thu 7/309:10 pm
MYR
- MCI
1 stop4h 05m
Southwest
Deal found 7/20![Southwest logo]()
$273
This Delta deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/287:00 am
MCI
- MYR
1 stop5h 00m
Delta
Wed 8/126:00 am
MYR
- MCI
1 stop4h 19m
Delta
Deal found 7/18![Delta logo]()
$265
This Delta deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:39 am
MCI
- MYR
1 stop4h 08m
Delta
Thu 8/66:00 am
MYR
- MCI
1 stop4h 19m
Delta
Deal found 7/21![Delta logo]()
$283
This Delta deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/312:22 pm
MCI
- MYR
1 stop4h 45m
Delta
Tue 8/117:02 pm
MYR
- MCI
1 stop5h 56m
Delta
Deal found 7/21![Delta logo]()
$275
This Southwest deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/121:25 pm
MCI
- MYR
1 stop4h 55m
Southwest
Sat 8/229:55 am
MYR
- MCI
1 stop8h 20m
Southwest
Deal found 7/22![Southwest logo]()
$267
This Delta deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:43 am
MCI
- MYR
1 stop4h 04m
Delta
Mon 8/176:00 am
MYR
- MCI
1 stop4h 19m
Delta
Deal found 7/20![Delta logo]()
$288
This American Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/141:04 pm
MCI
- MYR
1 stop6h 55m
American Airlines
Fri 8/218:08 am
MYR
- MCI
1 stop5h 06m
American Airlines
Deal found 7/18![American Airlines logo]()
$274
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/154:32 pm
MCI
- MYR
1 stop5h 45m
American Airlines
Tue 8/254:23 pm
MYR
- MCI
1 stop7h 27m
American Airlines
Deal found 7/21![American Airlines logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/174:09 pm
STL
- MYR
1 stop16h 56m
Multiple Airlines
Sun 8/239:07 pm
MYR
- STL
2 stops21h 15m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$303
This Delta deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:18 pm
MCI
- MYR
1 stop5h 12m
Delta
Mon 8/247:02 pm
MYR
- MCI
1 stop5h 56m
Delta
Deal found 7/19![Delta logo]()
$257
This Southwest deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2510:20 am
MCI
- MYR
2 stops8h 00m
Southwest
Sat 8/299:55 am
MYR
- MCI
1 stop6h 15m
Southwest
Deal found 7/20![Southwest logo]()
$262
This Southwest deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/269:20 am
MCI
- MYR
2 stops8h 50m
Southwest
Wed 9/22:25 pm
MYR
- MCI
1 stop6h 45m
Southwest
Deal found 7/22![Southwest logo]()
$272
One-way flights from Missouri to Myrtle BeachSearch for one-way flight options from Missouri to Myrtle Beach. Find affordable one-way fares based on user searches. Data last updated July 23, 2026.
Search for one-way flight options from Missouri to Myrtle Beach. Find affordable one-way fares based on user searches. Data last updated July 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2510:35 am
STL
- MYR
2 stops44h 05m
Frontier
Deal found 7/22![Frontier logo]()
$89
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1910:35 am
STL
- MYR
2 stops20h 05m
Frontier
Deal found 7/22![Frontier logo]()
$90
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1710:35 am
STL
- MYR
2 stops20h 05m
Frontier
Deal found 7/21![Frontier logo]()
$94
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:11 pm
MCI
- MYR
2 stops36h 29m
Frontier
Deal found 7/22![Frontier logo]()
$101
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:11 pm
MCI
- MYR
2 stops36h 29m
Frontier
Deal found 7/20![Frontier logo]()
$104
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:11 pm
MCI
- MYR
2 stops36h 29m
Frontier
Deal found 7/23![Frontier logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:17 pm
STL
- MYR
2 stops38h 48m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:34 pm
STL
- MYR
2 stops19h 48m
Multiple Airlines
Deal found 7/19![Multiple Airlines logo]()
$108
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2310:35 am
STL
- MYR
2 stops44h 05m
Frontier
Deal found 7/22![Frontier logo]()
$113
This Kiwi.com deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/144:57 pm
STL
- MYR
2 stops40h 05m
Multiple Airlines
Deal found 7/19![Multiple Airlines logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:17 pm
STL
- MYR
2 stops18h 49m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2310:35 am
STL
- MYR
2 stops24h 39m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$119
Find flight deals from Missouri to Myrtle Beach
Keep the following information in mind while searching for Missouri to Myrtle Beach flight deals. Data was last updated July 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $257 (Delta) |
One-way from | $91 (Kiwi.com) |
Popular in | April |
Cheapest in | February |
Average price | $427 |
Good round-trip deal | $494 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Myrtle Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 23, 2026.
Use the filters below to find and compare flights from Missouri to Myrtle Beach that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Kansas CityMyrtle Beach
MCI - MYR
MCIMYR
Kansas City
Fri 8/21
5:18 pm-11:30 pm
1 stop5h 12m
Myrtle Beach Intl
Mon 8/24
7:02 pm-11:58 pm
1 stop5h 56m
$257
Kansas CityMyrtle Beach
MCI - MYR
MCIMYR
Kansas City
Sun 8/16
2:00 pm-9:25 pm
1 stop6h 25m
Myrtle Beach Intl
Sun 8/23
6:50 pm-11:45 pm
1 stop5h 55m
$257
Kansas CityMyrtle Beach
MCI - MYR
MCIMYR
Kansas City
Sat 10/17
7:00 am-2:56 pm
1 stop6h 56m
Myrtle Beach Intl
Fri 10/23
6:00 am-12:27 pm
1 stop7h 27m
$257
Kansas CityMyrtle Beach
MCI - MYR
MCIMYR
Kansas City
Mon 8/3
12:22 pm-6:07 pm
1 stop4h 45m
Myrtle Beach Intl
Tue 8/4
7:02 pm-11:58 pm
1 stop5h 56m
$283
SpringfieldMyrtle Beach
SGF - MYR
SGFMYR
Springfield-Branson
Sat 9/5
4:00 pm-9:49 pm
1 stop4h 49m
Myrtle Beach Intl
Thu 9/10
5:45 pm-10:08 pm
1 stop5h 23m
$285
Quickest round-trip
Kansas CityMyrtle Beach
MCI - MYR
MCIMYR
Kansas City
Thu 8/13
5:43 am-10:47 am
1 stop4h 04m
Myrtle Beach Intl
Mon 8/17
6:00 am-9:19 am
1 stop4h 19m
$288
Kansas CityMyrtle Beach
MCI - MYR
MCIMYR
Kansas City
Fri 8/14
1:40 pm-7:20 pm
1 stop4h 40m
Myrtle Beach Intl
Fri 8/21
2:30 pm-9:50 pm
2 stops8h 20m
$293
SpringfieldMyrtle Beach
SGF - MYR
SGFMYR
Springfield-Branson
Wed 9/9
4:00 pm-9:41 pm
1 stop4h 41m
Myrtle Beach Intl
Thu 9/10
5:45 pm-10:08 pm
1 stop5h 23m
$295
Kansas CityMyrtle Beach
MCI - MYR
MCIMYR
Kansas City
Mon 9/14
5:10 am-2:45 pm
2 stops8h 35m
Myrtle Beach Intl
Mon 9/21
2:30 pm-10:35 pm
1 stop9h 05m
$299
SpringfieldMyrtle Beach
SGF - MYR
SGFMYR
Springfield-Branson
Sat 9/26
4:00 pm-9:41 pm
1 stop4h 41m
Myrtle Beach Intl
Sat 10/3
6:00 am-11:21 am
1 stop6h 21m
$312
Showing 1-10 of 55 resultsSorted by cheapest first
Best time to book a flight from Missouri to Myrtle Beach
Have a flexible travel schedule? Discover the best time to fly to Myrtle Beach from Missouri with our price prediction graph.
MCI-MYR
STL-MYR
COU-MYR
SGF-MYR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Myrtle Beach
USMO-MYR
MCI-MYR
STL-MYR
COU-MYR
SGF-MYR
What is the cheapest month to book a flight from Missouri to Myrtle Beach?
Currently, October is the cheapest month in which you can book a flight from Missouri to Myrtle Beach (average of $339). Flying from Missouri to Myrtle Beach in April is currently the most expensive (average of $498). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to MYR?
Find hourly flight availability from Missouri to Myrtle Beach. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 23, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Myrtle Beach as you normally would.
How much does it cost to fly round-trip from Missouri to Myrtle Beach?
How far ahead should I book a flight from Missouri to Myrtle Beach?
The best time to book flights from Missouri to Myrtle Beach is 40 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Myrtle Beach. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Myrtle Beach?
Book flights to Myrtle Beach if you plan to visit one of these locationsConway
Pawleys Island
Little River
Sunset Beach
Garden City Beach
Surfside Beach
Browse thousands of different options on Cheapflights for your next trip
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Complete your trip
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Other flights to Myrtle Beach
Explore flights to Myrtle Beach departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 23, 2026.
Missouri and Myrtle Beach flights
Browse other Missouri and Myrtle Beach flight options. Last updated on July 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Missouri to Myrtle Beach flights
Consider these flights traveling from Missouri to Myrtle Beach.
Top 4 airlines flying from Missouri to Myrtle Beach
Discover the top 4 airlines that operate flights from Missouri to Myrtle Beach. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$163 | Average$394 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$193 | Average$448 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$196 | Average$338 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$288 | Average$433 | FlexibilityNo cancel fee | On-time63% |