$99+ Cheap flights from Missouri to Myrtle Beach (MYR)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/30. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MYR
Oct 8 — Oct 151
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Missouri to Myrtle Beach with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missouri to Myrtle Beach
Cheapest
Best
Last-minute
One-way
Cheapest flights from Missouri to Myrtle BeachExplore the most affordable flight options available from Missouri to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 8, 2026.
Explore the most affordable flight options available from Missouri to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 8, 2026.
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3010:59 am -
1 stop4h 56m
Wed 10/76:30 am -
1 stop4h 04m
Deal found 9/3![American Airlines logo]()
$269
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:10 pm -
1 stop6h 20m
Tue 10/67:50 am -
1 stop6h 40m
Deal found 9/7![Southwest logo]()
$279
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/132:20 pm -
1 stop7h 32m
Sat 10/178:12 pm -
1 stop4h 46m
Deal found 9/3![American Airlines logo]()
$287
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:32 pm -
1 stop4h 15m
Fri 10/235:00 am -
1 stop5h 34m
Deal found 9/3![American Airlines logo]()
$292
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:47 pm -
1 stop5h 39m
Sat 10/245:00 am -
1 stop7h 01m
Deal found 9/7![American Airlines logo]()
$295
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:19 pm -
1 stop15h 46m
Mon 10/122:41 pm -
1 stop9h 32m
Deal found 9/4![Multiple Airlines logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/174:30 pm -
1 stop15h 20m
Tue 10/204:03 pm -
2 stops26h 37m
Deal found 9/5![Multiple Airlines logo]()
$308
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:00 am -
1 stop7h 37m
Tue 9/297:25 pm -
1 stop4h 34m
Deal found 9/3![American Airlines logo]()
$317
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:35 pm -
2 stops16h 09m
Mon 10/122:41 pm -
1 stop9h 32m
Deal found 9/5![Multiple Airlines logo]()
$324
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/319:31 am -
1 stop5h 54m
Tue 11/310:17 am -
1 stop5h 06m
Deal found 9/7![American Airlines logo]()
$332
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/312:15 pm -
1 stop6h 05m
Sat 11/75:55 pm -
1 stop5h 15m
Deal found 9/7![Southwest logo]()
$345
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/124:26 pm -
1 stop15h 19m
Wed 12/25:58 pm -
2 stops38h 11m
Deal found 9/4![Multiple Airlines logo]()
$365
Best flights from Missouri to Myrtle BeachDiscover carefully curated flight deals from Missouri to Myrtle Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 8, 2026.
Discover carefully curated flight deals from Missouri to Myrtle Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 8, 2026.
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/319:31 am -
1 stop5h 54m
Tue 11/310:17 am -
2 stops10h 02m
Deal found 9/7![American Airlines logo]()
$341
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2511:30 am -
1 stop7h 15m
Tue 9/292:25 pm -
2 stops8h 50m
Deal found 9/3![Southwest logo]()
$362
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/308:00 am -
2 stops7h 49m
Wed 2/311:28 am -
2 stops12h 54m
Deal found 9/3![United Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:35 pm -
1 stop4h 22m
Wed 10/212:16 pm -
1 stop4h 59m
Deal found 9/7![Delta logo]()
$433
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/48:58 am -
1 stop25h 46m
Sat 10/105:58 pm -
1 stop15h 05m
Deal found 9/3![Multiple Airlines logo]()
$438
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:47 pm -
1 stop7h 05m
Sat 10/244:12 pm -
2 stops7h 13m
Deal found 9/7![American Airlines logo]()
$354
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/262:00 pm -
2 stops6h 50m
Fri 10/301:25 pm -
2 stops6h 40m
Deal found 9/7![Southwest logo]()
$390
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/95:40 pm -
1 stop3h 49m
Sun 12/135:10 am -
1 stop6h 45m
Deal found 9/5![American Airlines logo]()
$367
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:11 pm -
2 stops13h 33m
Tue 10/2010:23 am -
2 stops13h 12m
Deal found 9/5![United Airlines logo]()
$427
This Southwest deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:35 pm -
1 stop5h 10m
Tue 10/205:00 pm -
1 stop6h 20m
Deal found 9/5![Southwest logo]()
$409
This Delta deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:34 pm -
1 stop4h 54m
Fri 10/1610:52 am -
1 stop6h 55m
Deal found 9/4![Delta logo]()
$478
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3012:59 pm -
1 stop18h 51m
Sun 11/13:23 pm -
2 stops20h 20m
Deal found 9/6![Multiple Airlines logo]()
$478
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:15 am -
1 stop7h 02m
Tue 9/2912:30 pm -
2 stops11h 25m
Deal found 9/4![United Airlines logo]()
$459
This Southwest deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1010:40 am -
2 stops7h 55m
Fri 10/163:55 pm -
2 stops8h 05m
Deal found 9/5![Southwest logo]()
$419
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/256:32 pm -
1 stop4h 15m
Fri 10/305:00 am -
1 stop5h 34m
Deal found 9/5![American Airlines logo]()
$438
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/178:00 am -
1 stop10h 25m
Thu 9/242:30 pm -
2 stops6h 25m
Deal found 9/3![Southwest logo]()
$429
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/28:07 pm -
1 stop11h 43m
Fri 10/166:42 pm -
2 stops38h 21m
Deal found 9/4![Multiple Airlines logo]()
$522
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:20 am -
2 stops10h 58m
Wed 9/2310:10 am -
2 stops13h 25m
Deal found 9/4![United Airlines logo]()
$499
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/121:20 pm -
1 stop5h 40m
Mon 11/167:05 pm -
1 stop3h 50m
Deal found 9/6![Southwest logo]()
$433
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/148:00 am -
2 stops8h 11m
Thu 11/1911:27 am -
2 stops12h 31m
Deal found 9/6![United Airlines logo]()
$507
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2110:55 am -
2 stops8h 15m
Wed 10/286:40 pm -
1 stop4h 50m
Deal found 9/7![Southwest logo]()
$438
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/97:35 am -
2 stops8h 14m
Tue 1/1211:28 am -
2 stops13h 04m
Deal found 9/7![United Airlines logo]()
$523
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:30 am -
2 stops6h 45m
Wed 10/1410:25 am -
1 stop5h 30m
Deal found 9/7![Southwest logo]()
$438
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2010:55 am -
2 stops8h 15m
Tue 10/271:35 pm -
2 stops6h 25m
Deal found 9/7![Southwest logo]()
$443
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:39 pm -
2 stops14h 05m
Sat 10/1710:38 am -
2 stops12h 22m
Deal found 9/3![United Airlines logo]()
$544
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/17:58 am -
1 stop6h 08m
Fri 2/56:12 am -
1 stop6h 52m
Deal found 9/7![American Airlines logo]()
$665
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1611:40 am -
2 stops8h 50m
Tue 10/278:40 am -
2 stops7h 20m
Deal found 9/7![Southwest logo]()
$443
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:11 pm -
2 stops13h 33m
Wed 10/710:23 am -
2 stops12h 37m
Deal found 9/4![United Airlines logo]()
$547
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3012:01 pm -
2 stops10h 46m
Sun 11/11:29 pm -
2 stops9h 46m
Deal found 9/6![American Airlines logo]()
$665
This Southwest deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:45 am -
2 stops6h 15m
Wed 12/210:45 am -
2 stops7h 55m
Deal found 9/4![Southwest logo]()
$443
Last-minute flights from Missouri to Myrtle BeachDiscover last-minute flight deals from Missouri to Myrtle Beach. Data last updated September 8, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Myrtle Beach. Data last updated September 8, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:00 am -
1 stop7h 37m
Tue 9/297:25 pm -
1 stop4h 34m
Deal found 9/3![American Airlines logo]()
$317
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2511:30 am -
1 stop7h 15m
Tue 9/292:25 pm -
2 stops8h 50m
Deal found 9/3![Southwest logo]()
$362
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:53 am -
1 stop5h 33m
Sat 10/312:10 pm -
1 stop6h 20m
Deal found 9/3![American Airlines logo]()
$367
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3010:59 am -
1 stop4h 56m
Wed 10/76:30 am -
1 stop4h 04m
Deal found 9/3![American Airlines logo]()
$269
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:10 pm -
1 stop6h 20m
Tue 10/67:50 am -
1 stop6h 40m
Deal found 9/7![Southwest logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:19 pm -
1 stop15h 46m
Mon 10/122:41 pm -
1 stop9h 32m
Deal found 9/4![Multiple Airlines logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:35 pm -
2 stops16h 09m
Mon 10/122:41 pm -
1 stop9h 32m
Deal found 9/5![Multiple Airlines logo]()
$324
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/132:20 pm -
1 stop7h 32m
Sat 10/178:12 pm -
1 stop4h 46m
Deal found 9/3![American Airlines logo]()
$287
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:32 pm -
1 stop4h 15m
Fri 10/235:00 am -
1 stop5h 34m
Deal found 9/3![American Airlines logo]()
$292
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/174:30 pm -
1 stop15h 20m
Tue 10/204:03 pm -
2 stops26h 37m
Deal found 9/5![Multiple Airlines logo]()
$308
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:47 pm -
1 stop5h 39m
Sat 10/245:00 am -
1 stop7h 01m
Deal found 9/7![American Airlines logo]()
$295
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/319:31 am -
1 stop5h 54m
Tue 11/310:17 am -
1 stop5h 06m
Deal found 9/7![American Airlines logo]()
$332
One-way flights from Missouri to Myrtle BeachSearch for one-way flight options from Missouri to Myrtle Beach. Find affordable one-way fares based on user searches. Data last updated September 8, 2026.
Search for one-way flight options from Missouri to Myrtle Beach. Find affordable one-way fares based on user searches. Data last updated September 8, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:44 pm -
2 stops38h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Frontier logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:35 pm -
2 stops37h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Frontier logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:35 pm -
2 stops37h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Frontier logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:44 pm -
2 stops37h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Frontier logo]()
$113
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/22:29 pm -
2 stops41h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Frontier logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:44 pm -
2 stops40h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected ” under the list of providers to see comparable flight deals.
Wed 10/216:35 pm -
2 stops40h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Multiple Airlines logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:35 pm -
2 stops40h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Multiple Airlines logo]()
$128
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:32 pm -
1 stop4h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Delta logo]()
$135
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:35 am -
2 stops6h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Southwest logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/59:16 am -
1 stop23h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$144
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:04 am -
1 stop6h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Delta logo]()
$145
Find flight deals from Missouri to Myrtle Beach
Keep the following information in mind while searching for Missouri to Myrtle Beach flight deals. Data was last updated September 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $269 (American Airlines) |
One-way from | $99 (Kiwi.com) |
Popular in | April |
Cheapest in | February |
Average price | $386 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Myrtle Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 8, 2026.
Use the filters below to find and compare flights from Missouri to Myrtle Beach that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Kansas CityMyrtle Beach
MCI Kansas City - MYR Myrtle Beach Intl
MCIMYR
Kansas City
Tue 9/29
5:30 pm-11:28 pm
1 stop4h 58m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$135
Kansas CityMyrtle Beach
MCI Kansas City - MYR Myrtle Beach Intl
MCIMYR
Kansas City
Mon 11/2
5:35 am-1:00 pm
2 stops6h 25m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$140
Kansas CityMyrtle Beach
MCI Kansas City - MYR Myrtle Beach Intl
MCIMYR
Kansas City
Sat 10/31
2:36 pm-8:28 pm
1 stop4h 52m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$158
Kansas CityMyrtle Beach
MCI Kansas City - MYR Myrtle Beach Intl
MCIMYR
Kansas City
Tue 11/3
8:05 am-3:01 pm
1 stop5h 56m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$158
St. LouisMyrtle Beach
STL Lambert-St Louis - MYR Myrtle Beach Intl
STLMYR
Lambert-St Louis
Wed 12/9
2:59 pm-3:03 pm
2 stops23h 04m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$167
Kansas CityMyrtle Beach
MCI Kansas City - MYR Myrtle Beach Intl
MCIMYR
Kansas City
Fri 12/4
4:49 pm-9:28 am
1 stop15h 39m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$168
St. LouisMyrtle Beach
STL Lambert-St Louis - MYR Myrtle Beach Intl
STLMYR
Lambert-St Louis
Sat 12/5
2:33 pm-9:40 pm
1 stop6h 07m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$182
St. LouisMyrtle Beach
STL Lambert-St Louis - MYR Myrtle Beach Intl
STLMYR
Lambert-St Louis
Thu 12/10
7:03 am-1:33 pm
1 stop5h 30m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$182
St. LouisMyrtle Beach
STL Lambert-St Louis - MYR Myrtle Beach Intl
STLMYR
Lambert-St Louis
Mon 10/12
5:35 pm-10:57 pm
1 stop4h 22m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$184
Quickest round-trip
St. LouisMyrtle Beach
STL Lambert-St Louis - MYR Myrtle Beach Intl
STLMYR
Lambert-St Louis
Tue 11/3
10:25 am-3:01 pm
1 stop3h 36m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$184
Showing 1-10 of 55 resultsSorted by cheapest first
Best time to book a flight from Missouri to Myrtle Beach
Have a flexible travel schedule? Discover the best time to fly to Myrtle Beach from Missouri with our price prediction graph.
MCI-MYR
SGF-MYR
STL-MYR
COU-MYR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Myrtle Beach
USMO-MYR
MCI-MYR
SGF-MYR
STL-MYR
COU-MYR
What is the cheapest month to book a flight from Missouri to Myrtle Beach?
Currently, October is the cheapest month in which you can book a flight from Missouri to Myrtle Beach (average of $335). Flying from Missouri to Myrtle Beach in April is currently the most expensive (average of $498). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to MYR?
Find hourly flight availability from Missouri to Myrtle Beach. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 8, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Myrtle Beach as you normally would.
How much does it cost to fly round-trip from Missouri to Myrtle Beach?
Airfare is below average for this route at the moment.
Missouri to Myrtle Beach flights typically cost between $329 and $507 in October.The cheapest round-trip price found within the last 5 days was $302 on Multiple Airlines (Oct 5-Oct 12).
How far ahead should I book a flight from Missouri to Myrtle Beach?
The best time to book flights from Missouri to Myrtle Beach is 39 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Myrtle Beach. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Myrtle Beach?
Book flights to Myrtle Beach if you plan to visit one of these locationsConway
Pawleys Island
Sunset Beach
Surfside Beach
Garden City Beach
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Myrtle Beach flight routes
Other flight options
Popular flights
Top destinations
Alternative routes for Missouri to Myrtle Beach
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Myrtle Beach by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Myrtle Beach by cabin class
Find flights from Missouri to Myrtle Beach, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Myrtle Beach
Explore flights to Myrtle Beach departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 8, 2026.
Missouri and Myrtle Beach flights
Browse other Missouri and Myrtle Beach flight options. Last updated on September 8, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Missouri to Myrtle Beach flights
Consider these flights traveling from Missouri to Myrtle Beach.
Top 4 airlines flying from Missouri to Myrtle Beach
Discover the top 4 airlines that operate flights from Missouri to Myrtle Beach. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$195 | Average$458 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$196 | Average$382 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$196 | Average$338 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$278 | Average$437 | FlexibilityNo cancel fee | On-time63% |