$133+ Cheap flights from Missouri to Myrtle Beach (MYR)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/16. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MYR
Nov 21 — Nov 281
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Missouri to Myrtle BeachExplore the most affordable flight options available from Missouri to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 22, 2026.
Explore the most affordable flight options available from Missouri to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 22, 2026.
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/103:00 pm -
1 stop6h 29m
Wed 11/1110:17 am -
1 stop4h 43m
Deal found 10/21![American Airlines logo]()
$289
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/74:49 pm -
1 stop16h 06m
Sat 12/125:58 pm -
1 stop24h 35m
Deal found 10/17![Multiple Airlines logo]()
$291
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:00 am -
2 stops10h 25m
Wed 11/113:25 pm -
1 stop6h 50m
Deal found 10/21![Southwest logo]()
$294
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/78:15 am -
2 stops9h 10m
Fri 12/117:35 pm -
1 stop5h 50m
Deal found 10/20![Southwest logo]()
$301
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/712:02 pm -
2 stops46h 42m
Sun 12/132:46 pm -
1 stop10h 26m
Deal found 10/21![Multiple Airlines logo]()
$308
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:30 am -
1 stop4h 02m
Tue 11/105:03 pm -
1 stop5h 48m
Deal found 10/22![American Airlines logo]()
$311
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/74:49 pm -
1 stop16h 06m
Mon 12/146:12 pm -
2 stops26h 23m
Deal found 10/17![Multiple Airlines logo]()
$315
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:59 am -
1 stop6h 12m
Tue 11/1011:27 am -
2 stops11h 13m
Deal found 10/22![United Airlines logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/74:49 pm -
1 stop16h 06m
Thu 12/178:10 pm -
1 stop22h 48m
Deal found 10/17![Multiple Airlines logo]()
$317
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/210:55 am -
2 stops7h 30m
Tue 12/87:05 pm -
1 stop3h 55m
Deal found 10/19![Southwest logo]()
$318
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/712:40 pm -
1 stop4h 45m
Fri 12/118:55 pm -
1 stop4h 00m
Deal found 10/20![Southwest logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/74:49 pm -
1 stop16h 06m
Tue 12/154:08 pm -
2 stops28h 27m
Deal found 10/17![Multiple Airlines logo]()
$327
Best flights from Missouri to Myrtle BeachDiscover carefully curated flight deals from Missouri to Myrtle Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 22, 2026.
Discover carefully curated flight deals from Missouri to Myrtle Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 22, 2026.
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/115:26 pm -
1 stop3h 59m
Tue 1/192:15 pm -
1 stop4h 17m
Deal found 10/20![Delta logo]()
$289
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:30 am -
1 stop4h 02m
Tue 11/105:03 pm -
1 stop5h 48m
Deal found 10/22![American Airlines logo]()
$311
This Southwest deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/25:55 am -
2 stops10h 30m
Tue 3/96:35 pm -
1 stop4h 35m
Deal found 10/18![Southwest logo]()
$380
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/69:59 am -
1 stop6h 12m
Tue 11/1011:27 am -
2 stops11h 13m
Deal found 10/21![United Airlines logo]()
$437
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/152:30 pm -
1 stop6h 55m
Sat 1/236:00 am -
1 stop4h 35m
Deal found 10/20![Delta logo]()
$329
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/234:08 pm -
1 stop5h 51m
Sat 2/271:48 pm -
1 stop5h 48m
Deal found 10/18![American Airlines logo]()
$335
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:28 pm -
1 stop4h 26m
Tue 11/246:58 pm -
1 stop4h 38m
Deal found 10/20![Delta logo]()
$372
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/512:55 pm -
1 stop6h 25m
Mon 11/98:55 pm -
1 stop4h 20m
Deal found 10/21![Southwest logo]()
$414
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/97:30 am -
2 stops9h 18m
Tue 1/1211:27 am -
2 stops11h 17m
Deal found 10/19![United Airlines logo]()
$445
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/129:59 am -
2 stops11h 26m
Sat 1/236:00 am -
1 stop4h 35m
Deal found 10/20![Delta logo]()
$375
This Southwest deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/61:25 pm -
2 stops7h 40m
Tue 11/107:05 pm -
1 stop3h 55m
Deal found 10/18![Southwest logo]()
$442
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/63:46 pm -
1 stop7h 09m
Wed 11/1110:17 am -
1 stop5h 06m
Deal found 10/20![American Airlines logo]()
$449
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/307:45 am -
2 stops9h 03m
Wed 2/311:27 am -
2 stops13h 03m
Deal found 10/18![United Airlines logo]()
$459
This Southwest deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/78:00 am -
2 stops10h 25m
Mon 12/143:25 pm -
2 stops7h 55m
Deal found 10/17![Southwest logo]()
$459
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/96:00 am -
1 stop4h 38m
Tue 4/1311:11 am -
2 stops6h 30m
Deal found 10/21![American Airlines logo]()
$492
This Southwest deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/111:30 pm -
2 stops5h 50m
Tue 2/161:40 pm -
2 stops9h 30m
Deal found 10/18![Southwest logo]()
$459
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/63:58 pm -
1 stop5h 49m
Tue 12/156:59 pm -
1 stop5h 57m
Deal found 10/17![Delta logo]()
$468
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/266:00 am -
1 stop6h 35m
Sun 3/286:00 am -
1 stop5h 48m
Deal found 10/19![Delta logo]()
$487
This Southwest deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/182:55 pm -
1 stop6h 00m
Sat 12/267:10 pm -
1 stop4h 40m
Deal found 10/17![Southwest logo]()
$487
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:15 am -
2 stops9h 08m
Wed 11/181:52 pm -
2 stops9h 23m
Deal found 10/18![American Airlines logo]()
$561
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/206:00 am -
1 stop6h 35m
Sat 3/2711:30 am -
1 stop4h 13m
Deal found 10/20![Delta logo]()
$487
This Southwest deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/257:05 am -
2 stops11h 20m
Wed 12/309:15 pm -
1 stop4h 00m
Deal found 10/17![Southwest logo]()
$492
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:31 pm -
1 stop4h 23m
Mon 11/3010:52 am -
1 stop4h 57m
Deal found 10/18![Delta logo]()
$489
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/113:00 pm -
3 stops18h 21m
Wed 11/1811:27 am -
2 stops12h 31m
Deal found 10/18![United Airlines logo]()
$717
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/139:10 am -
2 stops9h 05m
Wed 3/1710:55 am -
1 stop5h 00m
Deal found 10/20![Southwest logo]()
$494
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/312:40 pm -
1 stop4h 45m
Fri 11/67:35 pm -
1 stop5h 35m
Deal found 10/22![Southwest logo]()
$499
Last-minute flights from Missouri to Myrtle BeachDiscover last-minute flight deals from Missouri to Myrtle Beach. Data last updated October 22, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Myrtle Beach. Data last updated October 22, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:14 am -
1 stop4h 28m
Tue 10/278:13 am -
1 stop6h 53m
Deal found 10/21![American Airlines logo]()
$397
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:06 am -
1 stop5h 50m
Wed 11/181:52 pm -
1 stop6h 00m
Deal found 10/17![American Airlines logo]()
$381
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:30 am -
1 stop4h 02m
Tue 11/105:03 pm -
1 stop5h 48m
Deal found 10/22![American Airlines logo]()
$311
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:59 am -
1 stop6h 12m
Tue 11/1011:27 am -
2 stops11h 13m
Deal found 10/22![United Airlines logo]()
$316
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/103:00 pm -
1 stop6h 29m
Wed 11/1110:17 am -
1 stop4h 43m
Deal found 10/21![American Airlines logo]()
$289
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:00 am -
2 stops10h 25m
Wed 11/113:25 pm -
1 stop6h 50m
Deal found 10/21![Southwest logo]()
$294
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/169:46 am -
1 stop23h 09m
Fri 11/206:12 pm -
2 stops50h 22m
Deal found 10/17![Multiple Airlines logo]()
$364
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1610:25 am -
2 stops9h 32m
Mon 11/238:44 pm -
1 stop4h 14m
Deal found 10/19![American Airlines logo]()
$382
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:28 pm -
1 stop4h 26m
Tue 11/246:58 pm -
1 stop4h 38m
Deal found 10/20![Delta logo]()
$372
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1712:58 pm -
2 stops8h 31m
Tue 11/248:44 pm -
1 stop4h 14m
Deal found 10/20![American Airlines logo]()
$380
This Kiwi.com deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:34 pm -
2 stops16h 40m
Mon 11/232:41 pm -
1 stop10h 18m
Deal found 10/18![Multiple Airlines logo]()
$387
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:00 am -
1 stop4h 20m
Tue 11/248:44 pm -
1 stop4h 14m
Deal found 10/20![American Airlines logo]()
$399
One-way flights from Missouri to Myrtle BeachSearch for one-way flight options from Missouri to Myrtle Beach. Find affordable one-way fares based on user searches. Data last updated October 22, 2026.
Search for one-way flight options from Missouri to Myrtle Beach. Find affordable one-way fares based on user searches. Data last updated October 22, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/169:46 am -
1 stop23h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$133
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:10 am -
1 stop5h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Delta logo]()
$145
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:20 am -
1 stop4h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Southwest logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/306:21 pm -
2 stops36h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/17![Multiple Airlines logo]()
$168
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:58 pm -
3 stops39h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Multiple Airlines logo]()
$171
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/155:40 am -
1 stop6h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Delta logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/44:49 pm -
1 stop15h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/17![Multiple Airlines logo]()
$186
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:43 pm -
2 stops38h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$189
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:04 am -
1 stop6h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![American Airlines logo]()
$190
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/178:43 pm -
2 stops38h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$193
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:24 am -
1 stop4h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![American Airlines logo]()
$195
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/28:29 pm -
2 stops38h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/17![Multiple Airlines logo]()
$198
Find flight deals from Missouri to Myrtle Beach
Keep the following information in mind while searching for Missouri to Myrtle Beach flight deals. Data was last updated October 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $259 (Kiwi.com) |
One-way from | $133 (Kiwi.com) |
Popular in | April |
Cheapest in | February |
Average price | $412 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Myrtle Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 22, 2026.
Use the filters below to find and compare flights from Missouri to Myrtle Beach that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Kansas CityMyrtle Beach
MCI Kansas City - MYR Myrtle Beach Intl
MCIMYR
Kansas City
Wed 11/18
10:32 am-6:01 pm
1 stop6h 29m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$145
St. LouisMyrtle Beach
STL Lambert-St Louis - MYR Myrtle Beach Intl
STLMYR
Lambert-St Louis
Fri 12/4
7:20 am-1:15 pm
1 stop4h 55m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$164
St. LouisMyrtle Beach
STL Lambert-St Louis - MYR Myrtle Beach Intl
STLMYR
Lambert-St Louis
Fri 12/4
7:58 pm-12:14 pm
3 stops39h 16m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$171
Kansas CityMyrtle Beach
MCI Kansas City - MYR Myrtle Beach Intl
MCIMYR
Kansas City
Sun 11/15
5:40 am-1:33 pm
1 stop6h 53m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$185
Kansas CityMyrtle Beach
MCI Kansas City - MYR Myrtle Beach Intl
MCIMYR
Kansas City
Wed 11/25
5:31 pm-10:54 pm
1 stop4h 23m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$185
Kansas CityMyrtle Beach
MCI Kansas City - MYR Myrtle Beach Intl
MCIMYR
Kansas City
Fri 12/4
4:49 pm-9:28 am
1 stop15h 39m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$186
Kansas CityMyrtle Beach
MCI Kansas City - MYR Myrtle Beach Intl
MCIMYR
Kansas City
Thu 11/12
8:43 pm-11:44 am
2 stops38h 01m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$189
St. LouisMyrtle Beach
STL Lambert-St Louis - MYR Myrtle Beach Intl
STLMYR
Lambert-St Louis
Thu 11/12
5:04 am-12:16 pm
1 stop6h 12m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$190
St. LouisMyrtle Beach
STL Lambert-St Louis - MYR Myrtle Beach Intl
STLMYR
Lambert-St Louis
Wed 12/30
6:21 pm-8:03 am
3 stops36h 42m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$194
Kansas CityMyrtle Beach
MCI Kansas City - MYR Myrtle Beach Intl
MCIMYR
Kansas City
Sat 11/14
6:00 am-5:11 pm
2 stops10h 11m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$200
Showing 1-10 of 48 resultsSorted by cheapest first
Best time to book a flight from Missouri to Myrtle Beach
Have a flexible travel schedule? Discover the best time to fly to Myrtle Beach from Missouri with our price prediction graph.
MCI-MYR
STL-MYR
SGF-MYR
COU-MYR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Myrtle Beach
USMO-MYR
MCI-MYR
STL-MYR
SGF-MYR
COU-MYR
What is the cheapest month to book a flight from Missouri to Myrtle Beach?
Currently, February is the cheapest month in which you can book a flight from Missouri to Myrtle Beach (average of $353). Flying from Missouri to Myrtle Beach in April is currently the most expensive (average of $498). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Missouri to Myrtle Beach?
Airfare is below average for this route at the moment.
Missouri to Myrtle Beach flights typically cost between $359 and $457 in December.The cheapest round-trip price found within the last 5 days was $308 on Multiple Airlines (Dec 7-Dec 13).
How far ahead should I book a flight from Missouri to Myrtle Beach?
The best time to book flights from Missouri to Myrtle Beach is 39 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Myrtle Beach. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Myrtle Beach?
Book flights to Myrtle Beach if you plan to visit one of these locationsConway
Pawleys Island
Sunset Beach
Surfside Beach
Garden City Beach
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Alternative routes for Missouri to Myrtle Beach
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Complete your trip
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Find flights from Missouri to Myrtle Beach, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Myrtle Beach
Explore flights to Myrtle Beach departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 22, 2026.
Missouri and Myrtle Beach flights
Browse other Missouri and Myrtle Beach flight options. Last updated on October 22, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Missouri to Myrtle Beach flights
Consider these flights traveling from Missouri to Myrtle Beach.
Top 4 airlines flying from Missouri to Myrtle Beach
Discover the top 4 airlines that operate flights from Missouri to Myrtle Beach. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$195 | Average$463 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$196 | Average$392 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$196 | Average$338 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$278 | Average$447 | FlexibilityNo cancel fee | On-time63% |