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$444+ Cheap flights from District of Columbia to Florence, AL (MSL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/29. Fares are subject to change and may not be available on all flights or dates of travel.
IAD — MSL
Feb 19 — Feb 261
Thu 2/19
Thu 2/26
1 adult, Economy
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Cheap flight deals from District of Columbia to Florence

One-way flights from District of Columbia to Florence
Search for one-way flight options from District of Columbia to Florence. Find affordable one-way fares based on user searches. Data last updated January 20, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/296:00 pm
DCA
-
MSL
2 stops26h 10m
Multiple Airlines
Deal found 1/19$444

Cheapflights Fare Finder

 
Customize your flight search to find flights from District of Columbia to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 20, 2026.
Use the filters below to find and compare flights from District of Columbia to Florence that are best for you.

Fly from

District of Columbia

Fly to

Florence

Route

Depart

Return

Price

Washington, D.C.Florence

DCA - MSL

DCAMSL

Washington, D.C. Reagan-National

Thu 1/29

6:00 pm-7:10 pm

2 stops26h 10m

$444

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/19

Best time to book a flight from District of Columbia to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from District of Columbia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from District of Columbia to Florence

What is the cheapest month to book a flight from District of Columbia to Florence, Alabama?

Currently, August is the cheapest month in which you can book a flight from District of Columbia to Florence, Alabama (average of $199). Flying from District of Columbia to Florence, Alabama in November is currently the most expensive (average of $285). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from District of Columbia to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from District of Columbia?

    Most people fly into Florence Muscle Shoals (MSL) if they book a flight to Florence from District of Columbia. Muscle Shoals is conveniently located just 5.4 mi from Florence’s city center.

  • Can I find deals for flights from District of Columbia to Florence that include hotel bookings?

    Yes. In addition to deals on District of Columbia to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from District of Columbia to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from District of Columbia to Florence.

  • Can I find deals for business class flights from District of Columbia to Florence?

    Yes. Cheapflights offers flight deals from District of Columbia to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from District of Columbia to Florence, Alabama?

    Currently, August is the cheapest month in which you can book a flight from District of Columbia to Florence, Alabama (average of $199). Flying from District of Columbia to Florence, Alabama in November is currently the most expensive (average of $285). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sheffield
Muscle Shoals

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