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$289+ Cheap flights from Knoxville to Mobile (TYS - MOB)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/1. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MOB
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Knoxville to Mobile

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Mobile (MOB). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2025.

Round-trip from

$327
(Delta)

One-way from

$289
(Delta)
From Knoxville McGhee Tyson to Mobile
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One-way flight from Knoxville McGhee Tyson to Mobile
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Find flight deals from Knoxville to Mobile

Cheapest flights from Knoxville to Mobile
Explore the most affordable flight options available from Knoxville to Mobile. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/138:45 amTYS - MOB
1 stop4h 54mDelta
Tue 12/161:24 pmMOB - TYS
1 stop4h 35mDelta
Deal found 9/16$327
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/138:13 pmTYS - MOB
1 stop4h 54mAmerican Airlines
Tue 12/166:33 amMOB - TYS
2 stops9h 00mAmerican Airlines
Deal found 9/15$382
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/15:43 pmTYS - MOB
1 stop6h 28mAmerican Airlines
Sat 10/45:22 pmMOB - TYS
1 stop4h 41mAmerican Airlines
Deal found 9/16$387
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/165:44 amTYS - MOB
1 stop3h 49mDelta
Mon 10/206:59 pmMOB - TYS
1 stop3h 47mDelta
Deal found 9/16$427
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/155:44 amTYS - MOB
1 stop3h 49mDelta
Sun 10/196:59 pmMOB - TYS
1 stop3h 47mDelta
Deal found 9/17$433
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/26:30 amTYS - MOB
1 stop6h 51mAmerican Airlines
Mon 10/66:27 pmMOB - TYS
1 stop4h 23mAmerican Airlines
Deal found 9/16$453
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/176:08 pmTYS - MOB
1 stop6h 04mDelta
Sat 9/204:31 pmMOB - TYS
1 stop6h 13mDelta
Deal found 9/17$505
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/47:45 pmTYS - MOB
1 stop4h 25mAmerican Airlines
Mon 10/65:10 amMOB - TYS
1 stop4h 21mAmerican Airlines
Deal found 9/17$518
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/19:30 amTYS - MOB
1 stop13h 18mUnited Airlines
Tue 10/712:23 pmMOB - TYS
1 stop25h 22mUnited Airlines
Deal found 9/16$532
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/159:55 amTYS - MOB
1 stop10h 36mUnited Airlines
Sat 10/185:23 pmMOB - TYS
1 stop25h 29mUnited Airlines
Deal found 9/17$587

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Mobile that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Knoxville to Mobile that are best for you.

Fly from

Knoxville

Fly to

Mobile

Route

Depart

Return

Price

KnoxvilleMobile

TYS - MOB

TYSMOB

Knoxville McGhee Tyson

Sat 12/13

8:45 am-12:39 pm

1 stop4h 54m

Mobile

Tue 12/16

1:24 pm-6:59 pm

1 stop4h 35m

$327

KnoxvilleMobile

TYS - MOB

TYSMOB

Knoxville McGhee Tyson

Thu 10/16

5:44 am-8:33 am

1 stop3h 49m

Mobile

Mon 10/20

6:59 pm-11:46 pm

1 stop3h 47m

$327

KnoxvilleMobile

TYS - MOB

TYSMOB

Knoxville McGhee Tyson

Sat 12/13

8:13 pm-12:07 am

1 stop4h 54m

Mobile

Tue 12/16

6:33 am-4:33 pm

2 stops9h 00m

$382

KnoxvilleMobile

TYS - MOB

TYSMOB

Knoxville McGhee Tyson

Wed 10/1

5:43 pm-11:11 pm

1 stop6h 28m

Mobile

Sat 10/4

5:22 pm-11:03 pm

1 stop4h 41m

$387

KnoxvilleMobile

TYS - MOB

TYSMOB

Knoxville McGhee Tyson

Wed 10/15

5:44 am-8:33 am

1 stop3h 49m

Mobile

Sun 10/19

6:59 pm-11:46 pm

1 stop3h 47m

$433

KnoxvilleMobile

TYS - MOB

TYSMOB

Knoxville McGhee Tyson

Wed 10/15

5:44 am-8:33 am

1 stop3h 49m

Mobile

Sat 10/18

9:13 am-2:51 pm

1 stop4h 38m

$433

KnoxvilleMobile

TYS - MOB

TYSMOB

Knoxville McGhee Tyson

Thu 10/2

6:30 am-12:21 pm

1 stop6h 51m

Mobile

Mon 10/6

6:27 pm-11:50 pm

1 stop4h 23m

$453

KnoxvilleMobile

TYS - MOB

TYSMOB

Knoxville McGhee Tyson

Wed 10/1

9:30 am-9:48 pm

1 stop13h 18m

Mobile

Tue 10/7

12:23 pm-2:45 pm

1 stop25h 22m

$532

KnoxvilleMobile

TYS - MOB

TYSMOB

Knoxville McGhee Tyson

Wed 10/1

1:52 pm-6:12 pm

1 stop5h 20m

$289

KnoxvilleMobile

TYS - MOB

TYSMOB

Knoxville McGhee Tyson

Wed 10/1

7:00 am-10:28 am

3 stops28h 28m

$457

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Best time to book a flight from Knoxville to Mobile

Have a flexible travel schedule? Discover the best time to fly to Mobile from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Mobile

What is the cheapest month to book a flight from Knoxville to Mobile?

Currently, August is the cheapest month in which you can book a flight from Knoxville to Mobile (average of $348). Flying from Knoxville to Mobile in March is currently the most expensive (average of $468). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to MOB?

Find hourly flight availability from Knoxville to Mobile. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

It’s typically best to fly out from Knoxville to Mobile at noon. Doing so could potentially save you 25% on the flight price compared to flying in the morning, which is usually more expensive.

Reviews of airlines servicing Mobile

Get insights into the airlines that provide service to Mobile. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mobile. Reviews last updated September 17, 2025.
Peruse reviews from past customers who have flown with Delta from Knoxville to Mobile to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Crew

8.5

Food

7.3

Overall

8.0

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,961 reviews
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Crew

8.5

Food

7.3

Overall

8.0

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Mobile. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Mobile?

    There are many flights that can get you from Knoxville to Mobile in 4h 54m. Fly via Delta or American Airlines to get the fastest option. The distance between Knoxville and Mobile is about 430 mi.

  • What is the cheapest airline to fly from Knoxville to Mobile round-trip?

    Flying on Delta is currently your cheapest option to Mobile, with prices starting at $393.

  • Can I find deals for flights from Knoxville to Mobile that include hotel bookings?

    Yes. In addition to deals on Knoxville to Mobile flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Mobile?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Mobile.

  • Can I find deals for business class flights from Knoxville to Mobile?

    Yes. Cheapflights offers flight deals from Knoxville to Mobile by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Mobile?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to Mobile (average of $348). Flying from Knoxville to Mobile in March is currently the most expensive (average of $468). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Mobile?

Book flights to Mobile if you plan to visit one of these locations
Pascagoula
Moss Point

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Top airline flying from Knoxville to Mobile

Discover the top airline that operate flights from Knoxville to Mobile. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$393Average$634FlexibilityNo cancel feeOn-timeN/A

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