$333+ Cheap flights from Mobile to Knoxville (MOB - TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/17. Fares are subject to change and may not be available on all flights or dates of travel.
MOB — TYS
Oct 30 — Nov 61
Round-trip
1 adult, Economy
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Find cheap flights from Mobile to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Mobile to Knoxville
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Best
Last-minute
One-way
Cheapest flights from Mobile to KnoxvilleExplore the most affordable flight options available from Mobile to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 30, 2026.
Explore the most affordable flight options available from Mobile to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 30, 2026.
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:00 am -
1 stop3h 54m
Sat 10/315:40 am -
1 stop5h 38m
Deal found 9/27![Delta logo]()
$407
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/224:34 pm -
1 stop4h 34m
Mon 10/262:38 pm -
1 stop4h 02m
Deal found 9/28![Delta logo]()
$417
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/59:10 am -
1 stop3h 21m
Mon 11/95:40 am -
1 stop3h 52m
Deal found 9/29![Delta logo]()
$437
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/186:20 pm -
1 stop4h 33m
Tue 12/226:38 am -
1 stop6h 41m
Deal found 9/25![American Airlines logo]()
$562
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:16 am -
1 stop7h 02m
Mon 11/94:12 pm -
1 stop5h 48m
Deal found 9/29![American Airlines logo]()
$656
This Delta deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1212:06 pm -
1 stop4h 22m
Fri 10/166:23 pm -
1 stop5h 54m
Deal found 9/26![Delta logo]()
$665
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:30 pm -
1 stop4h 29m
Mon 10/195:40 am -
1 stop3h 50m
Deal found 9/29![Delta logo]()
$723
Best flights from Mobile to KnoxvilleDiscover carefully curated flight deals from Mobile to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 30, 2026.
Discover carefully curated flight deals from Mobile to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 30, 2026.
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:00 am -
1 stop3h 54m
Sat 10/315:40 am -
1 stop5h 38m
Deal found 9/27![Delta logo]()
$407
This American Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:51 pm -
1 stop5h 04m
Sat 10/3112:53 pm -
2 stops11h 05m
Deal found 9/26![American Airlines logo]()
$725
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/224:34 pm -
1 stop4h 34m
Mon 10/262:38 pm -
1 stop4h 02m
Deal found 9/28![Delta logo]()
$417
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/127:00 am -
1 stop27h 17m
Fri 10/166:03 pm -
2 stops27h 05m
Deal found 9/26![United Airlines logo]()
$902
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/59:10 am -
1 stop3h 21m
Mon 11/95:40 am -
1 stop3h 52m
Deal found 9/29![Delta logo]()
$437
This Delta deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1212:06 pm -
1 stop4h 22m
Fri 10/166:23 pm -
1 stop5h 54m
Deal found 9/26![Delta logo]()
$665
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/229:25 am -
2 stops26h 49m
Mon 10/267:35 pm -
1 stop25h 40m
Deal found 9/26![United Airlines logo]()
$954
Last-minute flights from Mobile to KnoxvilleDiscover last-minute flight deals from Mobile to Knoxville. Data last updated September 30, 2026 and is based on user searches.
Discover last-minute flight deals from Mobile to Knoxville. Data last updated September 30, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:51 pm -
1 stop5h 04m
Sun 10/116:06 pm -
1 stop4h 48m
Deal found 9/30![American Airlines logo]()
$727
This Delta deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1212:06 pm -
1 stop4h 22m
Fri 10/166:23 pm -
1 stop5h 54m
Deal found 9/26![Delta logo]()
$665
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:30 pm -
1 stop4h 29m
Mon 10/195:40 am -
1 stop3h 50m
Deal found 9/29![Delta logo]()
$723
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/224:34 pm -
1 stop4h 34m
Mon 10/262:38 pm -
1 stop4h 02m
Deal found 9/28![Delta logo]()
$417
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:00 am -
1 stop3h 54m
Sat 10/315:40 am -
1 stop5h 38m
Deal found 9/27![Delta logo]()
$407
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:51 pm -
1 stop5h 04m
Sat 10/3112:53 pm -
2 stops11h 05m
Deal found 9/27![American Airlines logo]()
$725
One-way flights from Mobile to KnoxvilleSearch for one-way flight options from Mobile to Knoxville. Find affordable one-way fares based on user searches. Data last updated September 30, 2026.
Search for one-way flight options from Mobile to Knoxville. Find affordable one-way fares based on user searches. Data last updated September 30, 2026.
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1712:06 pm -
1 stop4h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Delta logo]()
$333
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:30 pm -
1 stop4h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Delta logo]()
$440
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1710:50 am -
2 stops22h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![United Airlines logo]()
$500
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:51 pm -
1 stop5h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![American Airlines logo]()
$541
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:00 am -
1 stop3h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Delta logo]()
$620
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1410:50 am -
2 stops12h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/26![United Airlines logo]()
$647
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/154:58 pm -
2 stops30h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![United Airlines logo]()
$653
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:00 am -
1 stop13h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![United Airlines logo]()
$667
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:15 am -
2 stops9h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![American Airlines logo]()
$762
Find flight deals from Mobile to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Mobile (MOB) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $407 (Delta) |
One-way from | $333 (Delta) |
Cheapflights Fare Finder
Customize your flight search to find flights from Mobile to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 30, 2026.
Use the filters below to find and compare flights from Mobile to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MobileKnoxville
MOB Mobile - TYS Knoxville McGhee Tyson
MOBTYS
Mobile
Sat 10/17
12:06 pm-5:38 pm
1 stop4h 32m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$333
MobileKnoxville
MOB Mobile - TYS Knoxville McGhee Tyson
MOBTYS
Mobile
Fri 10/23
6:00 am-10:54 am
1 stop3h 54m
Knoxville McGhee Tyson
Sat 10/31
5:40 am-10:18 am
1 stop5h 38m
$407
MobileKnoxville
MOB Mobile - TYS Knoxville McGhee Tyson
MOBTYS
Mobile
Thu 10/22
4:34 pm-10:08 pm
1 stop4h 34m
Knoxville McGhee Tyson
Mon 10/26
2:38 pm-5:40 pm
1 stop4h 02m
$417
MobileKnoxville
MOB Mobile - TYS Knoxville McGhee Tyson
MOBTYS
Mobile
Thu 11/5
9:10 am-1:31 pm
1 stop3h 21m
Knoxville McGhee Tyson
Mon 11/9
5:40 am-8:32 am
1 stop3h 52m
$437
Quickest round-trip
MobileKnoxville
MOB Mobile - TYS Knoxville McGhee Tyson
MOBTYS
Mobile
Thu 10/15
6:30 pm-11:59 pm
1 stop4h 29m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$440
MobileKnoxville
MOB Mobile - TYS Knoxville McGhee Tyson
MOBTYS
Mobile
Sat 10/17
10:50 am-9:53 am
2 stops22h 03m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$500
MobileKnoxville
MOB Mobile - TYS Knoxville McGhee Tyson
MOBTYS
Mobile
Thu 10/15
5:51 pm-11:55 pm
1 stop5h 04m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$541
MobileKnoxville
MOB Mobile - TYS Knoxville McGhee Tyson
MOBTYS
Mobile
Wed 10/14
12:53 pm-10:37 am
1 stop20h 44m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$647
MobileKnoxville
MOB Mobile - TYS Knoxville McGhee Tyson
MOBTYS
Mobile
Thu 10/15
4:58 pm-11:59 pm
2 stops30h 01m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$653
MobileKnoxville
MOB Mobile - TYS Knoxville McGhee Tyson
MOBTYS
Mobile
Mon 10/12
12:06 pm-5:28 pm
1 stop4h 22m
Knoxville McGhee Tyson
Fri 10/16
6:23 pm-11:17 pm
1 stop5h 54m
$665
Showing 1-10 of 15 resultsSorted by cheapest first
Compare providers for flights from Mobile to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Mobile to Knoxville in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Mobile-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Mobile-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Mobile-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Mobile-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Mobile-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Mobile to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Mobile with our price prediction graph.
MOB-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Mobile to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
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