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Missouri

$142+ Cheap flights from South Dakota to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/22. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — STL
Jan 7 — Jan 141
Wed 1/7
Wed 1/14
1 adult, Economy
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Cheap flight deals from South Dakota to Missouri

Cheapest flights from South Dakota to Missouri
Explore the most affordable flight options available from South Dakota to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 8, 2025.

This United Airlines deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1211:20 amFSD - STL
1 stop4h 20mUnited Airlines
Sun 12/145:27 pmSTL - FSD
1 stop4h 24mUnited Airlines
Deal found 12/6$309
This American Airlines deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:00 amFSD - MCI
1 stop6h 45mAmerican Airlines
Sat 12/137:36 pmMCI - FSD
1 stop4h 23mAmerican Airlines
Deal found 12/7$319
This United Airlines deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/126:00 amFSD - MCI
1 stop6h 40mUnited Airlines
Sat 1/37:40 amMCI - FSD
1 stop6h 47mUnited Airlines
Deal found 12/7$333
This Delta deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/174:25 pmRAP - MCI
1 stop5h 45mDelta
Sun 12/215:59 pmMCI - RAP
1 stop5h 42mDelta
Deal found 12/7$425
This American Airlines deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/177:00 amFSD - MCI
1 stop4h 50mAmerican Airlines
Mon 12/225:12 amMCI - FSD
1 stop5h 04mAmerican Airlines
Deal found 12/7$452
This United Airlines deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/118:00 amFSD - MCI
2 stops12h 47mUnited Airlines
Sat 12/139:02 amMCI - FSD
1 stop7h 19mUnited Airlines
Deal found 12/7$467
This Kiwi.com deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1810:20 pmRAP - MCI
1 stop15h 32mMultiple Airlines
Mon 12/2211:13 amMCI - RAP
2 stops24h 02mMultiple Airlines
Deal found 12/7$477
This Mytrip deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1210:12 amFSD - STL
2 stops8h 24mMultiple Airlines
Sun 12/142:47 pmSTL - FSD
2 stops18h 35mMultiple Airlines
Deal found 12/6$520
This Kiwi.com deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/810:12 amFSD - STL
2 stops8h 24mMultiple Airlines
Wed 12/107:43 pmSTL - FSD
1 stop17h 48mMultiple Airlines
Deal found 12/6$523
This United Airlines deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/172:55 pmRAP - MCI
1 stop4h 52mUnited Airlines
Mon 12/225:07 pmMCI - RAP
1 stop5h 52mUnited Airlines
Deal found 12/7$524
This United Airlines deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/178:00 amFSD - MCI
2 stops12h 47mUnited Airlines
Mon 12/227:40 amMCI - FSD
1 stop6h 47mUnited Airlines
Deal found 12/7$542
This United Airlines deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/215:12 pmFSD - MCI
1 stop6h 03mUnited Airlines
Thu 12/255:07 pmMCI - FSD
1 stop6h 48mUnited Airlines
Deal found 12/6$579

Find flight deals from South Dakota to Missouri

Keep the following information in mind while searching for South Dakota to Missouri flight deals. Data was last updated December 8, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$229
(Delta)

One-way from

$142
(Mytrip)

Popular in

July

Cheapest in

January

Average price

$299
Provider with most accurate pricing for Sioux Falls Joe Foss Field-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Sioux Falls Joe Foss Field-Lambert-St Louis flights.
Search Deals
From South Dakota to Missouri
Search Deals
One-way flight from South Dakota to Missouri
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($10 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Dakota to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 8, 2025.
Use the filters below to find and compare flights from South Dakota to Missouri that are best for you.

Fly from

South Dakota

Fly to

Missouri

Route

Depart

Return

Price

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Fri 1/23

11:02 am-2:38 pm

1 stop3h 36m

Lambert-St Louis

Sun 1/25

6:10 am-10:22 am

1 stop4h 12m

$229

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Fri 5/1

11:44 am-4:55 pm

1 stop5h 11m

Lambert-St Louis

Sat 5/9

2:33 pm-8:46 pm

1 stop6h 13m

$229

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Thu 1/22

11:02 am-2:38 pm

1 stop3h 36m

Lambert-St Louis

Sat 1/31

11:23 am-3:37 pm

1 stop4h 14m

$229

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Fri 5/1

11:44 am-4:55 pm

1 stop5h 11m

Lambert-St Louis

Tue 5/5

2:33 pm-8:46 pm

1 stop6h 13m

$229

Rapid CityKansas City

RAP - MCI

RAPMCI

Rapid City

Wed 3/11

6:00 am-11:37 am

1 stop4h 37m

Kansas City

Mon 3/16

5:40 pm-10:26 pm

1 stop5h 46m

$249

Rapid CitySt. Louis

RAP - STL

RAPSTL

Rapid City

Wed 1/14

10:45 am-4:55 pm

1 stop5h 10m

Lambert-St Louis

Sat 1/17

4:15 pm-8:32 pm

1 stop5h 17m

$249

Rapid CitySt. Louis

RAP - STL

RAPSTL

Rapid City

Wed 1/7

10:54 am-4:45 pm

1 stop4h 51m

Lambert-St Louis

Sat 1/10

6:10 am-10:13 am

1 stop5h 03m

$249

Rapid CitySt. Louis

RAP - STL

RAPSTL

Rapid City

Thu 1/8

4:10 pm-11:25 pm

1 stop6h 15m

Lambert-St Louis

Sat 1/10

6:10 am-10:13 am

1 stop5h 03m

$249

Rapid CitySt. Louis

RAP - STL

RAPSTL

Rapid City

Wed 1/7

2:40 pm-8:58 pm

1 stop5h 18m

Lambert-St Louis

Sat 1/10

11:20 am-7:14 pm

2 stops8h 54m

$254

Sioux FallsKansas City

FSD - MCI

FSDMCI

Sioux Falls Joe Foss Field

Fri 1/30

9:00 am-4:08 pm

1 stop7h 08m

Kansas City

Sun 2/1

1:42 pm-8:24 pm

1 stop6h 42m

$255

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/7

Showing 1-10 of 34 results
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Best time to book a flight from South Dakota to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from South Dakota with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Dakota to Missouri

What is the cheapest month to book a flight from South Dakota to Missouri?

Currently, May is the cheapest month in which you can book a flight from South Dakota to Missouri (average of $188). Flying from South Dakota to Missouri in November is currently the most expensive (average of $275). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SD to MO?

Find hourly flight availability from South Dakota to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 8, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 45% on flights from South Dakota to Missouri by exploring options for tickets in the evening.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated December 8, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from South Dakota to Missouri have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,013 reviews

Crew

8.5

Food

7.3

Comfort

7.9

Overall

7.9

Entertainment

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,013 reviews
Delta
7.9
Good
8,013 reviews

Crew

8.5

Food

7.3

Comfort

7.9

Overall

7.9

Entertainment

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,076 reviews
Delta
7.9
Good
8,013 reviews

Crew

8.5

Food

7.3

Comfort

7.9

Overall

7.9

Entertainment

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,042 reviews
Delta
7.9
Good
8,013 reviews

Crew

8.5

Food

7.3

Comfort

7.9

Overall

7.9

Entertainment

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from South Dakota to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Dakota to Missouri?

    Airlines like Delta, United Airlines, and American Airlines fly from South Dakota to Missouri in about 3h 36m. The time it takes to get you to your destination can typically vary by up to 2h 12m. South Dakota and Missouri are separated by a distance of 470 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from South Dakota to Missouri that include hotel bookings?

    Yes. In addition to deals on South Dakota to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Dakota to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Dakota to Missouri.

  • Can I find deals for business class flights from South Dakota to Missouri?

    Yes. Cheapflights offers flight deals from South Dakota to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Dakota to Missouri?

    Currently, May is the cheapest month in which you can book a flight from South Dakota to Missouri (average of $188). Flying from South Dakota to Missouri in November is currently the most expensive (average of $275). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Dakota to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from South Dakota to Missouri

Discover the top 3 airlines that operate flights from South Dakota to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 8, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$343FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$212Average$441FlexibilityNo cancel feeOn-time69%
DeltaCheapest$228Average$320FlexibilityNo cancel feeOn-timeN/A

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