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Missouri

$137+ Cheap flights from South Dakota to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/31. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — STL
Nov 12 — Nov 191
Wed 11/12
Wed 11/19
1 adult, Economy
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Cheap flight deals from South Dakota to Missouri

Keep the following information in mind while searching for South Dakota to Missouri flight deals. Data was last updated October 13, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$229
(American Airlines)

One-way from

$137
(Frontier)

Popular in

December

Cheapest in

April

Average price

$377
Provider with most accurate pricing for Sioux Falls Joe Foss Field-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Sioux Falls Joe Foss Field-Lambert-St Louis flights.
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From South Dakota to Missouri
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One-way flight from South Dakota to Missouri
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Highest demand for flights based on searches. 10% potential increase in price ($39 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from South Dakota to Missouri

Cheapest flights from South Dakota to Missouri
Explore the most affordable flight options available from South Dakota to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 13, 2025.

This American Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:00 amFSD - STL
1 stop6h 34mAmerican Airlines
Sun 12/77:00 amSTL - FSD
1 stop5h 22mAmerican Airlines
Deal found 10/13$229
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/268:26 pmFSD - STL
1 stop22h 32mFrontier
Wed 12/37:43 pmSTL - FSD
1 stop22h 55mFrontier
Deal found 10/12$233
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/16:00 amFSD - MCI
1 stop7h 00mAmerican Airlines
Tue 11/43:04 pmMCI - FSD
1 stop6h 06mAmerican Airlines
Deal found 10/12$234
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/288:47 amFSD - STL
1 stop7h 41mUnited Airlines
Sat 11/15:24 pmSTL - FSD
1 stop4h 22mUnited Airlines
Deal found 10/13$239
This Delta deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/810:33 amRAP - MCI
1 stop3h 58mDelta
Sat 11/156:40 amMCI - RAP
1 stop4h 47mDelta
Deal found 10/10$249
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/315:15 amRAP - MCI
1 stop4h 26mUnited Airlines
Sun 11/21:47 pmMCI - RAP
1 stop5h 56mUnited Airlines
Deal found 10/13$259
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/285:15 amRAP - STL
1 stop6h 24mUnited Airlines
Sat 11/14:43 pmSTL - RAP
1 stop6h 15mUnited Airlines
Deal found 10/13$259
This American Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/85:18 amRAP - MCI
1 stop7h 48mAmerican Airlines
Sat 11/152:56 pmMCI - RAP
1 stop7h 20mAmerican Airlines
Deal found 10/10$279
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/185:14 pmFSD - STL
1 stop6h 44mUnited Airlines
Wed 10/223:23 pmSTL - FSD
1 stop6h 59mUnited Airlines
Deal found 10/12$279
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2610:05 amFSD - STL
2 stops8h 31mMultiple Airlines
Wed 12/37:43 pmSTL - FSD
1 stop22h 55mMultiple Airlines
Deal found 10/12$282
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3112:31 pmFSD - MCI
1 stop6h 38mAmerican Airlines
Fri 11/76:05 amMCI - FSD
1 stop4h 22mAmerican Airlines
Deal found 10/12$283
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/312:32 pmFSD - MCI
1 stop5h 01mMultiple Airlines
Mon 11/36:00 amMCI - FSD
2 stops14h 02mMultiple Airlines
Deal found 10/12$304

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Dakota to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 13, 2025.
Use the filters below to find and compare flights from South Dakota to Missouri that are best for you.

Fly from

South Dakota

Fly to

Missouri

Route

Depart

Return

Price

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Tue 11/11

5:18 am-8:55 am

1 stop3h 37m

Lambert-St Louis

Tue 11/18

5:34 pm-11:00 pm

1 stop5h 26m

$229

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Fri 12/5

8:00 am-12:15 pm

1 stop4h 15m

Lambert-St Louis

Mon 12/8

4:37 pm-11:43 pm

1 stop7h 06m

$229

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Thu 12/4

6:00 am-12:34 pm

1 stop6h 34m

Lambert-St Louis

Sun 12/7

7:00 am-12:22 pm

1 stop5h 22m

$229

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Thu 1/22

7:30 am-2:30 pm

1 stop7h 00m

Lambert-St Louis

Sun 1/25

6:30 am-10:47 am

1 stop4h 17m

$229

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Tue 3/3

5:15 am-8:54 am

1 stop3h 39m

Lambert-St Louis

Sat 3/7

5:30 pm-10:58 pm

1 stop5h 28m

$229

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Wed 11/26

8:26 pm-6:58 pm

1 stop22h 32m

Lambert-St Louis

Wed 12/3

7:43 pm-6:38 pm

1 stop22h 55m

$233

Sioux FallsKansas City

FSD - MCI

FSDMCI

Sioux Falls Joe Foss Field

Sat 11/1

6:00 am-1:00 pm

1 stop7h 00m

Kansas City

Tue 11/4

3:04 pm-9:10 pm

1 stop6h 06m

$234

Sioux FallsKansas City

FSD - MCI

FSDMCI

Sioux Falls Joe Foss Field

Sat 11/1

6:49 am-11:43 am

1 stop4h 54m

Kansas City

Wed 11/5

1:45 pm-9:10 pm

1 stop7h 25m

$234

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Tue 10/28

8:47 am-4:28 pm

1 stop7h 41m

Lambert-St Louis

Sat 11/1

5:24 pm-9:46 pm

1 stop4h 22m

$239

Rapid CityKansas City

RAP - MCI

RAPMCI

Rapid City

Sat 11/8

10:33 am-3:31 pm

1 stop3h 58m

Kansas City

Sat 11/15

6:40 am-10:27 am

1 stop4h 47m

$249

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/12

Showing 1-10 of 53 results
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Best time to book a flight from South Dakota to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from South Dakota with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Dakota to Missouri

What is the cheapest month to book a flight from South Dakota to Missouri?

Currently, May is the cheapest month in which you can book a flight from South Dakota to Missouri (average of $188). Flying from South Dakota to Missouri in September is currently the most expensive (average of $264). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SD to MO?

Find hourly flight availability from South Dakota to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 13, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 45% on flights from South Dakota to Missouri by exploring options for tickets in the evening.

How much does it cost to fly round-trip from South Dakota to Missouri?

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated October 13, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from South Dakota to Missouri have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,973 reviews

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
8.0
Very good
7,973 reviews
Delta
8.0
Very good
7,973 reviews

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,974 reviews
Delta
8.0
Very good
7,973 reviews

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,045 reviews
Delta
8.0
Very good
7,973 reviews

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from South Dakota to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Dakota to Missouri?

    Airlines like Delta, United Airlines, and American Airlines fly from South Dakota to Missouri in about 3h 37m. The time it takes to get you to your destination can typically vary by up to 3h 23m. South Dakota and Missouri are separated by a distance of 470 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from South Dakota to Missouri one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $137. Users have also found prices from $191 and $215 on United Airlines and Allegiant Air, respectively.

  • Can I find deals for flights from South Dakota to Missouri that include hotel bookings?

    Yes. In addition to deals on South Dakota to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Dakota to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Dakota to Missouri.

  • Can I find deals for business class flights from South Dakota to Missouri?

    Yes. Cheapflights offers flight deals from South Dakota to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Dakota to Missouri?

    Currently, May is the cheapest month in which you can book a flight from South Dakota to Missouri (average of $188). Flying from South Dakota to Missouri in September is currently the most expensive (average of $264). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Dakota to Missouri

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Top 3 airlines flying from South Dakota to Missouri

Discover the top 3 airlines that operate flights from South Dakota to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$348FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$212Average$459FlexibilityNo cancel feeOn-time69%
DeltaCheapest$228Average$329FlexibilityNo cancel feeOn-timeN/A

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