$135+ Cheap flights from South Dakota to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/27. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — STL
May 6 — May 131
Round-trip
1 adult, Economy
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Cheapest flights from South Dakota to MissouriExplore the most affordable flight options available from South Dakota to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 6, 2026.
Explore the most affordable flight options available from South Dakota to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 6, 2026.
This Frontier deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/224:25 pm
FSD
- STL
1 stop26h 58m
Frontier
Thu 5/288:08 pm
STL
- FSD
1 stop19h 32m
Frontier
Deal found 4/3![Frontier logo]()
$205
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/297:45 pm
FSD
- STL
1 stop4h 01m
American Airlines
Wed 5/67:12 am
STL
- FSD
1 stop5h 44m
American Airlines
Deal found 4/1![American Airlines logo]()
$281
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/145:00 am
FSD
- STL
1 stop3h 46m
Delta
Tue 5/195:36 pm
STL
- FSD
1 stop5h 35m
Delta
Deal found 4/4![Delta logo]()
$290
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:47 am
FSD
- STL
1 stop7h 16m
American Airlines
Sat 5/25:20 am
STL
- FSD
1 stop7h 36m
American Airlines
Deal found 4/1![American Airlines logo]()
$295
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/244:57 pm
RAP
- MCI
1 stop5h 01m
American Airlines
Sun 4/265:33 am
MCI
- RAP
1 stop6h 50m
American Airlines
Deal found 4/2![American Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:39 pm
FSD
- STL
1 stop4h 17m
American Airlines
Sun 5/177:05 am
STL
- FSD
1 stop4h 54m
American Airlines
Deal found 4/1![American Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/223:17 pm
FSD
- SGF
1 stop7h 21m
American Airlines
Wed 4/296:05 pm
SGF
- FSD
1 stop5h 06m
American Airlines
Deal found 4/1![American Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1012:25 pm
FSD
- MCI
1 stop7h 58m
American Airlines
Sat 9/125:46 am
MCI
- FSD
1 stop5h 46m
American Airlines
Deal found 4/1![American Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:15 am
FSD
- STL
1 stop3h 25m
Delta
Sat 9/265:30 pm
STL
- FSD
1 stop5h 16m
Delta
Deal found 4/1![Delta logo]()
$314
This United Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:10 am
FSD
- MCI
1 stop6h 14m
United Airlines
Sat 4/256:00 am
MCI
- FSD
1 stop6h 50m
United Airlines
Deal found 4/4![United Airlines logo]()
$314
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:47 am
FSD
- STL
1 stop7h 16m
American Airlines
Mon 4/205:20 am
STL
- FSD
1 stop7h 36m
American Airlines
Deal found 4/1![American Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/173:55 pm
RAP
- STL
1 stop6h 19m
Delta
Tue 4/216:20 am
STL
- RAP
1 stop4h 57m
Delta
Deal found 4/2![Delta logo]()
$319
Best flights from South Dakota to MissouriDiscover carefully curated flight deals from South Dakota to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 6, 2026.
Discover carefully curated flight deals from South Dakota to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 6, 2026.
This Frontier deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/224:25 pm
FSD
- STL
1 stop26h 58m
Frontier
Thu 5/288:08 pm
STL
- FSD
1 stop19h 32m
Frontier
Deal found 4/3![Frontier logo]()
$205
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/145:00 am
FSD
- STL
1 stop3h 46m
Delta
Tue 5/195:36 pm
STL
- FSD
1 stop5h 35m
Delta
Deal found 4/4![Delta logo]()
$290
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:30 am
FSD
- STL
1 stop7h 15m
American Airlines
Sat 9/510:14 am
STL
- FSD
1 stop7h 08m
American Airlines
Deal found 4/2![American Airlines logo]()
$290
This United Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:10 am
FSD
- MCI
1 stop6h 14m
United Airlines
Sat 4/256:00 am
MCI
- FSD
1 stop6h 50m
United Airlines
Deal found 4/4![United Airlines logo]()
$314
This Kiwi.com deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/278:53 pm
FSD
- STL
2 stops33h 57m
Multiple Airlines
Wed 4/294:59 pm
STL
- FSD
1 stop17h 46m
Multiple Airlines
Deal found 4/3![Multiple Airlines logo]()
$350
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/145:54 pm
FSD
- STL
1 stop5h 47m
American Airlines
Sat 9/197:44 am
STL
- FSD
1 stop3h 48m
American Airlines
Deal found 4/5![American Airlines logo]()
$290
This Delta deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:15 am
FSD
- STL
1 stop3h 25m
Delta
Sat 9/265:30 pm
STL
- FSD
1 stop5h 16m
Delta
Deal found 4/1![Delta logo]()
$314
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1911:35 am
FSD
- SGF
1 stop29h 16m
Allegiant Air
Thu 4/2310:24 am
SGF
- FSD
2 stops31h 24m
Allegiant Air
Deal found 4/4![Allegiant Air logo]()
$646
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:39 pm
FSD
- STL
1 stop4h 17m
American Airlines
Sun 5/177:05 am
STL
- FSD
1 stop4h 54m
American Airlines
Deal found 4/1![American Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:00 am
FSD
- STL
1 stop7h 13m
United Airlines
Sat 5/95:28 pm
STL
- FSD
1 stop4h 24m
United Airlines
Deal found 4/2![United Airlines logo]()
$341
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/223:17 pm
FSD
- SGF
1 stop7h 21m
American Airlines
Wed 4/296:05 pm
SGF
- FSD
1 stop5h 06m
American Airlines
Deal found 4/1![American Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:00 pm
FSD
- STL
1 stop6h 43m
United Airlines
Tue 10/69:23 am
STL
- FSD
1 stop5h 12m
United Airlines
Deal found 4/1![United Airlines logo]()
$341
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:54 pm
FSD
- MCI
1 stop5h 07m
American Airlines
Sat 9/125:30 am
MCI
- FSD
1 stop6h 16m
American Airlines
Deal found 4/2![American Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/77:40 am
FSD
- STL
1 stop4h 31m
United Airlines
Fri 8/145:32 pm
STL
- FSD
1 stop6h 05m
United Airlines
Deal found 4/6![United Airlines logo]()
$348
This United Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/177:39 am
FSD
- STL
1 stop4h 43m
United Airlines
Mon 4/206:05 pm
STL
- FSD
1 stop5h 39m
United Airlines
Deal found 4/4![United Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/277:39 pm
FSD
- STL
1 stop16h 08m
American Airlines
Wed 4/2912:27 pm
STL
- FSD
1 stop6h 48m
American Airlines
Deal found 4/3![American Airlines logo]()
$367
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/411:25 am
FSD
- MCI
1 stop4h 57m
United Airlines
Mon 6/87:11 pm
MCI
- FSD
1 stop4h 42m
United Airlines
Deal found 4/1![United Airlines logo]()
$378
This United Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/179:30 am
FSD
- MCI
1 stop6h 52m
United Airlines
Sun 7/194:56 pm
MCI
- FSD
1 stop5h 11m
United Airlines
Deal found 4/3![United Airlines logo]()
$379
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:30 am
FSD
- MCI
1 stop6h 56m
United Airlines
Sat 5/96:29 pm
MCI
- FSD
1 stop5h 00m
United Airlines
Deal found 4/1![United Airlines logo]()
$379
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:10 am
FSD
- MCI
1 stop4h 17m
United Airlines
Mon 4/205:05 pm
MCI
- FSD
1 stop4h 49m
United Airlines
Deal found 4/1![United Airlines logo]()
$389
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/284:58 pm
RAP
- SGF
1 stop6h 00m
American Airlines
Sun 8/303:43 pm
SGF
- RAP
1 stop7h 15m
American Airlines
Deal found 4/1![American Airlines logo]()
$507
This United Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/184:57 pm
FSD
- MCI
1 stop6h 35m
United Airlines
Wed 4/221:54 pm
MCI
- FSD
1 stop6h 36m
United Airlines
Deal found 4/3![United Airlines logo]()
$389
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2811:08 am
RAP
- STL
1 stop4h 23m
United Airlines
Tue 9/14:40 pm
STL
- RAP
1 stop4h 52m
United Airlines
Deal found 4/1![United Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/188:30 am
RAP
- STL
2 stops14h 27m
United Airlines
Wed 4/228:54 am
STL
- RAP
1 stop5h 14m
United Airlines
Deal found 4/3![United Airlines logo]()
$404
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/12:35 pm
RAP
- STL
2 stops8h 49m
United Airlines
Mon 5/45:28 pm
STL
- RAP
1 stop5h 18m
United Airlines
Deal found 4/1![United Airlines logo]()
$404
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/25:20 am
RAP
- MCI
1 stop6h 23m
United Airlines
Tue 5/58:49 am
MCI
- RAP
1 stop5h 20m
United Airlines
Deal found 4/1![United Airlines logo]()
$409
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1412:29 pm
FSD
- SGF
2 stops9h 25m
American Airlines
Sun 5/175:19 am
SGF
- FSD
1 stop6h 40m
American Airlines
Deal found 4/1![American Airlines logo]()
$863
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/78:19 am
FSD
- SGF
2 stops9h 47m
Delta
Sun 5/106:05 am
SGF
- FSD
2 stops9h 31m
Delta
Deal found 4/4![Delta logo]()
$1,455
This United Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:00 am
FSD
- SGF
1 stop4h 42m
United Airlines
Mon 5/111:35 pm
SGF
- FSD
1 stop6h 45m
United Airlines
Deal found 4/4![United Airlines logo]()
$485
This Delta deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:00 am
FSD
- SGF
2 stops10h 14m
Delta
Wed 4/296:05 am
SGF
- FSD
2 stops9h 32m
Delta
Deal found 4/1![Delta logo]()
$1,467
Last-minute flights from South Dakota to MissouriDiscover last-minute flight deals from South Dakota to Missouri. Data last updated April 6, 2026 and is based on user searches.
Discover last-minute flight deals from South Dakota to Missouri. Data last updated April 6, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:47 am
FSD
- STL
1 stop7h 16m
American Airlines
Mon 4/205:20 am
STL
- FSD
1 stop7h 36m
American Airlines
Deal found 4/1![American Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/173:55 pm
RAP
- STL
1 stop6h 19m
Delta
Tue 4/216:20 am
STL
- RAP
1 stop4h 57m
Delta
Deal found 4/2![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/172:47 pm
RAP
- STL
1 stop5h 07m
United Airlines
Tue 4/2110:00 am
STL
- RAP
2 stops10h 02m
United Airlines
Deal found 4/2![United Airlines logo]()
$324
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:47 am
FSD
- STL
1 stop7h 16m
American Airlines
Sat 5/25:20 am
STL
- FSD
1 stop7h 36m
American Airlines
Deal found 4/1![American Airlines logo]()
$295
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/223:17 pm
FSD
- SGF
1 stop7h 21m
American Airlines
Wed 4/296:05 pm
SGF
- FSD
1 stop5h 06m
American Airlines
Deal found 4/1![American Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:10 am
FSD
- MCI
1 stop6h 14m
United Airlines
Sat 4/256:00 am
MCI
- FSD
1 stop6h 50m
United Airlines
Deal found 4/4![United Airlines logo]()
$314
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/244:57 pm
RAP
- MCI
1 stop5h 01m
American Airlines
Sun 4/265:33 am
MCI
- RAP
1 stop6h 50m
American Airlines
Deal found 4/2![American Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/297:45 pm
FSD
- STL
1 stop4h 01m
American Airlines
Wed 5/67:12 am
STL
- FSD
1 stop5h 44m
American Airlines
Deal found 4/1![American Airlines logo]()
$281
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:52 pm
FSD
- STL
1 stop4h 04m
United Airlines
Sat 5/95:28 pm
STL
- FSD
1 stop6h 01m
United Airlines
Deal found 4/5![United Airlines logo]()
$341
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/145:00 am
FSD
- STL
1 stop3h 46m
Delta
Tue 5/195:36 pm
STL
- FSD
1 stop5h 35m
Delta
Deal found 4/4![Delta logo]()
$290
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:39 pm
FSD
- STL
1 stop4h 17m
American Airlines
Sun 5/177:05 am
STL
- FSD
1 stop4h 54m
American Airlines
Deal found 4/1![American Airlines logo]()
$309
This Frontier deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/224:25 pm
FSD
- STL
1 stop26h 58m
Frontier
Thu 5/288:08 pm
STL
- FSD
1 stop19h 32m
Frontier
Deal found 4/3![Frontier logo]()
$205
One-way flights from South Dakota to MissouriSearch for one-way flight options from South Dakota to Missouri. Find affordable one-way fares based on user searches. Data last updated April 6, 2026.
Search for one-way flight options from South Dakota to Missouri. Find affordable one-way fares based on user searches. Data last updated April 6, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/276:11 pm
FSD
- STL
2 stops36h 39m
Multiple Airlines
Deal found 4/2![Multiple Airlines logo]()
$135
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/64:57 pm
RAP
- STL
1 stop5h 02m
American Airlines
Deal found 4/1![American Airlines logo]()
$211
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:47 pm
RAP
- SGF
1 stop5h 22m
American Airlines
Deal found 4/1![American Airlines logo]()
$221
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/85:00 pm
RAP
- SGF
1 stop5h 44m
American Airlines
Deal found 4/1![American Airlines logo]()
$222
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/277:39 pm
FSD
- STL
1 stop18h 24m
American Airlines
Deal found 4/2![American Airlines logo]()
$227
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/243:36 pm
FSD
- MCI
1 stop24h 34m
Multiple Airlines
Deal found 4/5![Multiple Airlines logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/269:50 pm
RAP
- STL
2 stops15h 58m
Multiple Airlines
Deal found 4/4![Multiple Airlines logo]()
$245
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/62:35 pm
RAP
- STL
2 stops8h 49m
United Airlines
Deal found 4/1![United Airlines logo]()
$248
This United Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/237:39 am
FSD
- MCI
1 stop4h 45m
United Airlines
Deal found 4/4![United Airlines logo]()
$318
This Kiwi.com deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/282:34 pm
RAP
- SGF
3 stops40h 28m
Multiple Airlines
Deal found 4/1![Multiple Airlines logo]()
$335
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/83:21 pm
RAP
- SGF
2 stops8h 24m
United Airlines
Deal found 4/1![United Airlines logo]()
$496
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/235:00 am
FSD
- MCI
2 stops8h 24m
Delta
Deal found 4/4![Delta logo]()
$555
Find flight deals from South Dakota to Missouri
Keep the following information in mind while searching for South Dakota to Missouri flight deals. Data was last updated April 6, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $205 (Frontier) |
One-way from | $135 (Kiwi.com) |
Popular in | July |
Cheapest in | September |
Average price | $374 |
Cheapflights Fare Finder
Customize your flight search to find flights from South Dakota to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 6, 2026.
Use the filters below to find and compare flights from South Dakota to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Fri 5/22
4:25 pm-7:23 pm
1 stop26h 58m
Lambert-St Louis
Thu 5/28
8:08 pm-3:40 pm
1 stop19h 32m
$205
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Thu 5/14
5:00 am-8:46 am
1 stop3h 46m
Lambert-St Louis
Tue 5/19
5:36 pm-11:11 pm
1 stop5h 35m
$290
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Thu 9/3
7:30 am-2:45 pm
1 stop7h 15m
Lambert-St Louis
Sat 9/5
10:14 am-5:22 pm
1 stop7h 08m
$290
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Mon 9/14
5:54 pm-11:41 pm
1 stop5h 47m
Lambert-St Louis
Sat 9/19
7:44 am-11:32 am
1 stop3h 48m
$290
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Thu 5/14
7:39 pm-11:56 pm
1 stop4h 17m
Lambert-St Louis
Sun 5/17
7:05 am-11:59 am
1 stop4h 54m
$309
Sioux FallsSpringfield
FSD - SGF
FSDSGF
Sioux Falls Joe Foss Field
Wed 4/22
3:17 pm-10:38 pm
1 stop7h 21m
Springfield-Branson
Wed 4/29
6:05 pm-11:11 pm
1 stop5h 06m
$309
Sioux FallsKansas City
FSD - MCI
FSDMCI
Sioux Falls Joe Foss Field
Thu 9/10
5:54 pm-11:01 pm
1 stop5h 07m
Kansas City
Sat 9/12
5:30 am-11:46 am
1 stop6h 16m
$309
Sioux FallsKansas City
FSD - MCI
FSDMCI
Sioux Falls Joe Foss Field
Thu 4/23
6:10 am-12:24 pm
1 stop6h 14m
Kansas City
Sat 4/25
6:00 am-12:50 pm
1 stop6h 50m
$314
Quickest round-trip
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Fri 9/25
5:15 am-8:40 am
1 stop3h 25m
Lambert-St Louis
Sat 9/26
5:30 pm-10:46 pm
1 stop5h 16m
$314
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Tue 5/5
6:00 am-1:13 pm
1 stop7h 13m
Lambert-St Louis
Sat 5/9
5:28 pm-9:52 pm
1 stop4h 24m
$341
Showing 1-10 of 42 resultsSorted by cheapest first
Best time to book a flight from South Dakota to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from South Dakota with our price prediction graph.
FSD-STL
FSD-MCI
FSD-SGF
RAP-SGF
RAP-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Dakota to Missouri
USSD-USMO
FSD-STL
FSD-MCI
FSD-SGF
RAP-SGF
What is the cheapest month to book a flight from South Dakota to Missouri?
Currently, May is the cheapest month in which you can book a flight from South Dakota to Missouri (average of $190). Flying from South Dakota to Missouri in February is currently the most expensive (average of $277). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from South Dakota to Missouri?
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated April 6, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from South Dakota to Missouri have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Comfort
7.9
Crew
8.5
Food
7.2
Boarding
8.1
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Entertainment
7.8
Comfort
7.9
Crew
8.5
Food
7.2
Boarding
8.1
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Entertainment
7.8
Comfort
7.9
Crew
8.5
Food
7.2
Boarding
8.1
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Entertainment
7.8
Comfort
7.9
Crew
8.5
Food
7.2
Boarding
8.1
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from South Dakota to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for South Dakota to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Dakota to Missouri by cabin class
Find flights from South Dakota to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Dakota and Missouri flights
Browse other South Dakota and Missouri flight options. Last updated on April 6, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to South Dakota after your stay in Missouri
South Dakota to Missouri flights
Consider these flights traveling from South Dakota to Missouri.
Top 3 airlines flying from South Dakota to Missouri
Discover the top 3 airlines that operate flights from South Dakota to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 6, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$174 | Average$361 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$212 | Average$412 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$253 | Average$414 | FlexibilityNo cancel fee | On-time71% |