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$126+ Cheap flights from South Dakota to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — STL
Dec 6 — Dec 131
Sat 12/6
Sat 12/13
1 adult, Economy
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Cheap flight deals from South Dakota to Missouri

Keep the following information in mind while searching for South Dakota to Missouri flight deals. Data was last updated November 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$229
(Delta)

One-way from

$126
(Delta)

Popular in

July

Cheapest in

August

Average price

$378
Provider with most accurate pricing for Sioux Falls Joe Foss Field-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Sioux Falls Joe Foss Field-Lambert-St Louis flights.
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From South Dakota to Missouri
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One-way flight from South Dakota to Missouri
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Highest demand for flights based on searches. 3% potential increase in price ($10 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from South Dakota to Missouri

Cheapest flights from South Dakota to Missouri
Explore the most affordable flight options available from South Dakota to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2010:10 pmRAP - STL
1 stop12h 06mMultiple Airlines
Mon 11/249:54 pmSTL - RAP
1 stop12h 49mMultiple Airlines
Deal found 11/5$237
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/205:18 amFSD - STL
1 stop3h 37mDelta
Mon 11/245:34 pmSTL - FSD
1 stop5h 26mDelta
Deal found 11/5$244
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/206:30 amFSD - MCI
1 stop7h 25mAmerican Airlines
Tue 12/22:49 pmMCI - FSD
1 stop6h 20mAmerican Airlines
Deal found 11/5$244
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/911:02 amRAP - STL
1 stop4h 47mDelta
Tue 12/166:00 amSTL - RAP
1 stop5h 22mDelta
Deal found 11/6$249
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2510:33 amRAP - STL
1 stop9h 36mMultiple Airlines
Sun 11/309:54 pmSTL - RAP
1 stop16h 19mMultiple Airlines
Deal found 11/5$260
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/246:05 amRAP - STL
1 stop4h 54mDelta
Wed 12/36:00 amSTL - RAP
1 stop5h 22mDelta
Deal found 11/5$264
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2510:33 amRAP - STL
1 stop9h 36mMultiple Airlines
Fri 11/2812:01 pmSTL - RAP
1 stop22h 12mMultiple Airlines
Deal found 11/6$266
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2011:46 amFSD - MCI
2 stops22h 32mMultiple Airlines
Tue 12/212:58 pmMCI - FSD
1 stop23h 52mMultiple Airlines
Deal found 11/5$267
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/156:30 amFSD - STL
1 stop6h 07mAmerican Airlines
Wed 11/195:17 amSTL - FSD
1 stop7h 06mAmerican Airlines
Deal found 11/5$279
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2011:46 amFSD - MCI
2 stops22h 32mMultiple Airlines
Sun 11/308:28 pmMCI - FSD
1 stop23h 03mMultiple Airlines
Deal found 11/5$286
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/198:45 amRAP - SGF
1 stop6h 37mUnited Airlines
Wed 12/35:08 pmSGF - RAP
1 stop4h 29mUnited Airlines
Deal found 11/6$294
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/217:16 pmFSD - STL
1 stop4h 46mAmerican Airlines
Tue 11/251:20 pmSTL - FSD
1 stop7h 49mAmerican Airlines
Deal found 11/6$299

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Dakota to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from South Dakota to Missouri that are best for you.

Fly from

South Dakota

Fly to

Missouri

Route

Depart

Return

Price

Sioux FallsKansas City

FSD - MCI

FSDMCI

Sioux Falls Joe Foss Field

Sat 4/4

10:55 am-3:07 pm

1 stop4h 12m

Kansas City

Wed 4/8

6:30 am-12:35 pm

1 stop6h 05m

$229

Sioux FallsKansas City

FSD - MCI

FSDMCI

Sioux Falls Joe Foss Field

Thu 11/20

6:30 am-1:55 pm

1 stop7h 25m

Kansas City

Tue 12/2

2:49 pm-9:09 pm

1 stop6h 20m

$244

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Thu 11/20

5:18 am-8:55 am

1 stop3h 37m

Lambert-St Louis

Mon 11/24

5:34 pm-11:00 pm

1 stop5h 26m

$244

Rapid CitySt. Louis

RAP - STL

RAPSTL

Rapid City

Tue 3/3

4:10 pm-11:25 pm

1 stop6h 15m

Lambert-St Louis

Sat 3/7

6:10 am-10:13 am

1 stop5h 03m

$249

Rapid CitySt. Louis

RAP - STL

RAPSTL

Rapid City

Tue 12/9

11:02 am-4:49 pm

1 stop4h 47m

Lambert-St Louis

Tue 12/16

6:00 am-10:22 am

1 stop5h 22m

$249

Rapid CitySt. Louis

RAP - STL

RAPSTL

Rapid City

Mon 11/24

6:05 am-11:59 am

1 stop4h 54m

Lambert-St Louis

Wed 12/3

6:00 am-10:22 am

1 stop5h 22m

$264

Rapid CitySt. Louis

RAP - STL

RAPSTL

Rapid City

Tue 11/25

10:33 am-9:09 pm

1 stop9h 36m

Lambert-St Louis

Fri 11/28

12:01 pm-9:13 am

1 stop22h 12m

$266

Rapid CitySt. Louis

RAP - STL

RAPSTL

Rapid City

Thu 11/20

10:10 pm-11:16 am

1 stop12h 06m

Lambert-St Louis

Mon 11/24

3:53 pm-9:43 am

2 stops18h 50m

$268

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Tue 3/3

8:10 am-2:58 pm

1 stop6h 48m

Lambert-St Louis

Sat 3/7

6:10 am-12:22 pm

1 stop6h 12m

$278

Rapid CitySpringfield

RAP - SGF

RAPSGF

Rapid City

Wed 11/19

8:45 am-4:22 pm

1 stop6h 37m

Springfield-Branson

Wed 12/3

5:08 pm-8:37 pm

1 stop4h 29m

$294

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/4

Showing 1-10 of 43 results
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Best time to book a flight from South Dakota to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from South Dakota with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Dakota to Missouri

What is the cheapest month to book a flight from South Dakota to Missouri?

Currently, May is the cheapest month in which you can book a flight from South Dakota to Missouri (average of $188). Flying from South Dakota to Missouri in September is currently the most expensive (average of $264). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SD to MO?

Find hourly flight availability from South Dakota to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 6, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 45% on flights from South Dakota to Missouri by exploring options for tickets in the evening.

How much does it cost to fly round-trip from South Dakota to Missouri?

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated November 6, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from South Dakota to Missouri have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,001 reviews

Crew

8.5

Food

7.3

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,001 reviews
Delta
7.9
Good
8,001 reviews

Crew

8.5

Food

7.3

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,007 reviews
Delta
7.9
Good
8,001 reviews

Crew

8.5

Food

7.3

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,040 reviews
Delta
7.9
Good
8,001 reviews

Crew

8.5

Food

7.3

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from South Dakota to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Dakota to Missouri?

    Airlines like Delta, American Airlines, and United Airlines fly from South Dakota to Missouri in about 4h 12m. The time it takes to get you to your destination can typically vary by up to 3h 13m. South Dakota and Missouri are separated by a distance of 314 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from South Dakota to Missouri that include hotel bookings?

    Yes. In addition to deals on South Dakota to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Dakota to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Dakota to Missouri.

  • Can I find deals for business class flights from South Dakota to Missouri?

    Yes. Cheapflights offers flight deals from South Dakota to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Dakota to Missouri?

    Currently, May is the cheapest month in which you can book a flight from South Dakota to Missouri (average of $188). Flying from South Dakota to Missouri in September is currently the most expensive (average of $264). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Dakota to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from South Dakota to Missouri

Discover the top 3 airlines that operate flights from South Dakota to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$344FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$212Average$453FlexibilityNo cancel feeOn-time69%
DeltaCheapest$228Average$330FlexibilityNo cancel feeOn-timeN/A

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