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Missouri

$111+ Cheap flights from South Dakota to Missouri

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/4. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — STL
dic. 13 — dic. 201
sáb. 12/13
sáb. 12/20
1 adult, Economy
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Cheap flight deals from South Dakota to Missouri

Keep the following information in mind while searching for South Dakota to Missouri flight deals. Data was last updated noviembre 13, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$111
(Frontier)

Popular in

July

Cheapest in

January

Average price

$378
Provider with most accurate pricing for Sioux Falls Joe Foss Field-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Sioux Falls Joe Foss Field-Lambert-St Louis flights.
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From South Dakota to Missouri
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Highest demand for flights based on searches. 5% potential increase in price ($18 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from South Dakota to Missouri

Cheapest flights from South Dakota to Missouri
Explore the most affordable flight options available from South Dakota to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on noviembre 13, 2025.

This Frontier deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/42:26 pmFSD - STL
1 stop19h 48mFrontier
mié. 12/107:43 pmSTL - FSD
1 stop17h 48mFrontier
Deal found 11/11$111
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/36:00 amFSD - STL
1 stop6h 32mAmerican Airlines
dom. 12/75:14 amSTL - FSD
1 stop7h 08mAmerican Airlines
Deal found 11/12$229
This Delta deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/94:25 pmRAP - STL
1 stop6h 04mDelta
mar. 12/166:00 amSTL - RAP
1 stop5h 22mDelta
Deal found 11/12$249
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/205:18 amFSD - STL
1 stop3h 37mDelta
jue. 11/276:00 amSTL - FSD
1 stop4h 18mDelta
Deal found 11/11$264
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/44:25 pmRAP - STL
1 stop6h 04mDelta
dom. 12/76:00 amSTL - RAP
1 stop5h 22mDelta
Deal found 11/11$264
This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/1110:19 pmRAP - MCI
1 stop15h 33mMultiple Airlines
lun. 12/2211:13 amMCI - RAP
2 stops24h 02mMultiple Airlines
Deal found 11/11$272
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/131:10 pmFSD - STL
1 stop6h 20mAmerican Airlines
jue. 11/205:17 amSTL - FSD
1 stop7h 19mAmerican Airlines
Deal found 11/12$309
This Delta deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/52:51 pmRAP - STL
2 stops7h 51mDelta
dom. 12/76:00 amSTL - RAP
1 stop5h 22mDelta
Deal found 11/13$314
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/151:03 pmFSD - SGF
1 stop6h 06mAmerican Airlines
lun. 11/177:17 pmSGF - FSD
1 stop4h 42mAmerican Airlines
Deal found 11/11$319
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/278:00 amFSD - STL
1 stop4h 28mUnited Airlines
lun. 12/15:24 pmSTL - FSD
1 stop4h 22mUnited Airlines
Deal found 11/12$334
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/218:45 amRAP - MCI
1 stop6h 20mUnited Airlines
dom. 11/235:10 pmMCI - RAP
1 stop5h 49mUnited Airlines
Deal found 11/12$339
This Delta deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/294:25 pmFSD - STL
1 stop5h 51mDelta
vie. 1/26:05 amSTL - FSD
1 stop6h 28mDelta
Deal found 11/13$359

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Dakota to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 13, 2025.
Use the filters below to find and compare flights from South Dakota to Missouri that are best for you.

Fly from

South Dakota

Fly to

Missouri

Route

Depart

Return

Price

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

jue. 12/4

2:26 pm-10:14 am

1 stop19h 48m

Lambert-St Louis

mié. 12/10

7:43 pm-1:31 pm

1 stop17h 48m

$111

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

mié. 12/3

7:00 am-12:44 pm

1 stop5h 44m

Lambert-St Louis

dom. 12/7

5:14 am-12:22 pm

1 stop7h 08m

$229

Sioux FallsKansas City

FSD - MCI

FSDMCI

Sioux Falls Joe Foss Field

sáb. 4/4

10:55 am-3:07 pm

1 stop4h 12m

Kansas City

mié. 4/8

6:30 am-12:35 pm

1 stop6h 05m

$229

Rapid CityKansas City

RAP - MCI

RAPMCI

Rapid City

mié. 2/18

4:10 pm-11:28 pm

1 stop6h 18m

Kansas City

sáb. 2/21

6:23 am-10:13 am

1 stop4h 50m

$249

Rapid CityKansas City

RAP - MCI

RAPMCI

Rapid City

sáb. 1/31

4:10 pm-11:27 pm

1 stop6h 17m

Kansas City

mar. 2/3

6:24 am-10:13 am

1 stop4h 49m

$249

Rapid CityKansas City

RAP - MCI

RAPMCI

Rapid City

vie. 1/30

4:10 pm-11:27 pm

1 stop6h 17m

Kansas City

jue. 2/5

6:24 am-10:13 am

1 stop4h 49m

$249

Rapid CityKansas City

RAP - MCI

RAPMCI

Rapid City

vie. 1/30

4:10 pm-11:27 pm

1 stop6h 17m

Kansas City

mié. 2/4

6:24 am-10:13 am

1 stop4h 49m

$249

Rapid CityKansas City

RAP - MCI

RAPMCI

Rapid City

jue. 1/29

10:54 am-5:09 pm

1 stop5h 15m

Kansas City

jue. 2/5

6:24 am-10:13 am

1 stop4h 49m

$249

Rapid CityKansas City

RAP - MCI

RAPMCI

Rapid City

sáb. 1/31

4:10 pm-11:27 pm

1 stop6h 17m

Kansas City

mié. 2/4

6:24 am-10:13 am

1 stop4h 49m

$249

Rapid CityKansas City

RAP - MCI

RAPMCI

Rapid City

jue. 1/29

10:54 am-5:09 pm

1 stop5h 15m

Kansas City

mié. 2/4

6:24 am-10:13 am

1 stop4h 49m

$249

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/13

Showing 1-10 of 37 results
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Best time to book a flight from South Dakota to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from South Dakota with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Dakota to Missouri

What is the cheapest month to book a flight from South Dakota to Missouri?

Currently, May is the cheapest month in which you can book a flight from South Dakota to Missouri (average of $188). Flying from South Dakota to Missouri in September is currently the most expensive (average of $264). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SD to MO?

Find hourly flight availability from South Dakota to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated noviembre 13, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 45% on flights from South Dakota to Missouri by exploring options for tickets in the evening.

How much does it cost to fly round-trip from South Dakota to Missouri?

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated noviembre 13, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from South Dakota to Missouri have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Crew

8.5

Food

7.3

Boarding

8.1

Entertainment

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Crew

8.5

Food

7.3

Boarding

8.1

Entertainment

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,017 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Crew

8.5

Food

7.3

Boarding

8.1

Entertainment

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,051 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Crew

8.5

Food

7.3

Boarding

8.1

Entertainment

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from South Dakota to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Dakota to Missouri?

    Airlines like Frontier, American Airlines, and Delta fly from South Dakota to Missouri in about 4h 12m. The time it takes to get you to your destination can typically vary by up to 15h 36m. South Dakota and Missouri are separated by a distance of 314 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from South Dakota to Missouri one-way?

    For one-way options, check prices for Delta. According to our data, you can fly for as low as $228. Users have also found prices from $281 and $500 on United Airlines and American Airlines, respectively.

  • Can I find deals for flights from South Dakota to Missouri that include hotel bookings?

    Yes. In addition to deals on South Dakota to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Dakota to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Dakota to Missouri.

  • Can I find deals for business class flights from South Dakota to Missouri?

    Yes. Cheapflights offers flight deals from South Dakota to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Dakota to Missouri?

    Currently, May is the cheapest month in which you can book a flight from South Dakota to Missouri (average of $188). Flying from South Dakota to Missouri in September is currently the most expensive (average of $264). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 3 airlines flying from South Dakota to Missouri

Discover the top 3 airlines that operate flights from South Dakota to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$344FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$212Average$453FlexibilityNo cancel feeOn-time69%
DeltaCheapest$228Average$330FlexibilityNo cancel feeOn-timeN/A

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