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$75+ Cheap flights from Pittsburgh (PIT) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/1. Fares are subject to change and may not be available on all flights or dates of travel.
PIT — STL
Nov 22 — Nov 291
Sat 11/22
Sat 11/29
1 adult, Economy
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Cheap flight deals from Pittsburgh to Missouri

Keep the following information in mind while searching for Pittsburgh to Missouri flight deals. Data was last updated October 23, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$159
(American Airlines)

One-way from

$75
(American Airlines)

Popular in

January

Cheapest in

April

Average price

$393

Good round-trip deal

$393 or less

Good one-way deal

$215 or less
Provider with most accurate pricing for Pittsburgh-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Pittsburgh-Lambert-St Louis flights.
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From Pittsburgh to Missouri
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One-way flight from Pittsburgh to Missouri
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Highest demand for flights based on searches. 4% potential increase in price ($14 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Price to beat on a round-trip flight from Pittsburgh to Missouri.
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Price to beat on a one-way flight from Pittsburgh to Missouri.
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Find flight deals from Pittsburgh to Missouri

Cheapest flights from Pittsburgh to Missouri
Explore the most affordable flight options available from Pittsburgh to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 23, 2025.

This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/41:49 pmPIT - STL
1 stop6h 41mAmerican Airlines
Sun 12/76:53 pmSTL - PIT
1 stop4h 42mAmerican Airlines
Deal found 10/21$159
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/237:40 pmPIT - STL
1 stop5h 02mDelta
Mon 1/55:45 pmSTL - PIT
1 stop3h 56mDelta
Deal found 10/21$177
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/311:26 pmPIT - MCI
1 stop7h 50mAmerican Airlines
Tue 1/66:00 amMCI - PIT
1 stop14h 00mAmerican Airlines
Deal found 10/22$189
This Mytrip deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1010:15 amPIT - MCI
1 stop9h 13mSpirit Airlines
Wed 11/126:00 amMCI - PIT
2 stops23h 21mSpirit Airlines
Deal found 10/21$212
This Mytrip deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1010:15 amPIT - MCI
1 stop9h 13mSpirit Airlines
Thu 11/136:00 amMCI - PIT
2 stops23h 21mSpirit Airlines
Deal found 10/21$217
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/910:15 amPIT - STL
1 stop8h 01mMultiple Airlines
Fri 11/144:56 pmSTL - PIT
2 stops12h 25mMultiple Airlines
Deal found 10/21$228
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/26:45 pmPIT - STL
1 stop15h 55mMultiple Airlines
Thu 11/67:02 pmSTL - PIT
1 stop25h 09mMultiple Airlines
Deal found 10/20$229
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/176:30 amPIT - MCI
1 stop8h 21mAmerican Airlines
Mon 12/226:36 pmMCI - PIT
1 stop4h 49mAmerican Airlines
Deal found 10/22$237
This Mytrip deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1010:15 amPIT - MCI
1 stop9h 13mMultiple Airlines
Thu 11/136:00 amMCI - PIT
1 stop16h 18mMultiple Airlines
Deal found 10/21$239
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/238:55 pmPIT - STL
1 stop4h 10mSouthwest
Mon 1/58:00 amSTL - PIT
Nonstop1h 40mSouthwest
Deal found 10/21$242
This KAYAK deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/35:40 pmPIT - STL
1 stop4h 07mDelta
Thu 12/46:00 amSTL - PIT
1 stop5h 41mDelta
Deal found 10/22$243
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/510:15 amPIT - STL
2 stops24h 57mMultiple Airlines
Thu 11/67:02 pmSTL - PIT
1 stop15h 07mMultiple Airlines
Deal found 10/22$244

Cheapflights Fare Finder

 
Customize your flight search to find flights from Pittsburgh to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 23, 2025.
Use the filters below to find and compare flights from Pittsburgh to Missouri that are best for you.

Fly from

Pittsburgh

Fly to

Missouri

Route

Depart

Return

Price

PittsburghSt. Louis

PIT - STL

PITSTL

Pittsburgh

Tue 12/23

7:40 pm-11:42 pm

1 stop5h 02m

Lambert-St Louis

Mon 1/5

5:45 pm-10:41 pm

1 stop3h 56m

$177

PittsburghKansas City

PIT - MCI

PITMCI

Pittsburgh

Mon 1/12

12:35 pm-7:50 pm

1 stop8h 15m

Kansas City

Sat 1/17

6:10 am-3:00 pm

1 stop7h 50m

$231

PittsburghSt. Louis

PIT - STL

PITSTL

Pittsburgh

Fri 2/6

8:30 am-7:41 pm

1 stop12h 11m

Lambert-St Louis

Mon 2/9

8:45 am-10:37 pm

2 stops12h 52m

$233

PittsburghKansas City

PIT - MCI

PITMCI

Pittsburgh

Thu 1/8

3:10 pm-11:08 am

2 stops20h 58m

Kansas City

Mon 1/12

12:13 pm-10:37 pm

1 stop9h 24m

$236

PittsburghSpringfield

PIT - SGF

PITSGF

Pittsburgh

Sat 11/22

5:47 pm-10:13 pm

1 stop5h 26m

Springfield-Branson

Tue 11/25

6:35 pm-11:44 pm

1 stop4h 09m

$249

PittsburghSpringfield

PIT - SGF

PITSGF

Pittsburgh

Thu 11/20

7:05 am-10:53 am

1 stop4h 48m

Springfield-Branson

Sun 11/23

6:58 pm-12:21 am

1 stop4h 23m

$249

PittsburghKansas City

PIT - MCI

PITMCI

Pittsburgh

Wed 11/12

10:06 pm-12:28 pm

2 stops15h 22m

Kansas City

Sat 11/15

6:00 am-6:21 am

2 stops23h 21m

$252

PittsburghSpringfield

PIT - SGF

PITSGF

Pittsburgh

Thu 11/20

10:35 am-5:46 pm

2 stops8h 11m

Springfield-Branson

Sun 11/23

9:00 am-3:47 pm

1 stop5h 47m

$254

PittsburghSt. Louis

PIT - STL

PITSTL

Pittsburgh

Sun 11/2

6:45 pm-9:40 am

1 stop15h 55m

Lambert-St Louis

Thu 11/6

11:07 am-6:21 am

2 stops18h 14m

$257

PittsburghSt. Louis

PIT - STL

PITSTL

Pittsburgh

Wed 11/12

3:30 pm-4:20 pm

Nonstop1h 50m

Lambert-St Louis

Wed 11/19

6:15 pm-8:50 pm

Nonstop1h 35m

$263

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/22

Showing 1-10 of 51 results
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Best time to book a flight from Pittsburgh to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Pittsburgh with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Pittsburgh to Missouri

What is the cheapest month to book a flight from Pittsburgh to Missouri?

Currently, December is the cheapest month in which you can book a flight from Pittsburgh to Missouri (average of $167). Flying from Pittsburgh to Missouri in July is currently the most expensive (average of $269). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PIT to MO?

Find hourly flight availability from Pittsburgh to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 23, 2025.

It’s optimal to fly from Pittsburgh to Missouri in the morning. By choosing this option you can save up to 51% on the cost of your flight, compared to a flight at noon.

What is the cheapest day to fly from Pittsburgh to Missouri?

Use this chart to determine the cheapest time to fly round-trip from Pittsburgh to Missouri. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Pittsburgh to Missouri flight should consider departing on Tuesday at noon when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated October 23, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Pittsburgh to Missouri by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,236 reviews

Comfort

8.0

Entertainment

7.5

Crew

8.6

Boarding

8.1

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,236 reviews
Southwest
8.0
Very good
4,236 reviews

Comfort

8.0

Entertainment

7.5

Crew

8.6

Boarding

8.1

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
7,982 reviews
Southwest
8.0
Very good
4,236 reviews

Comfort

8.0

Entertainment

7.5

Crew

8.6

Boarding

8.1

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
8,995 reviews
Southwest
8.0
Very good
4,236 reviews

Comfort

8.0

Entertainment

7.5

Crew

8.6

Boarding

8.1

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,032 reviews
Southwest
8.0
Very good
4,236 reviews

Comfort

8.0

Entertainment

7.5

Crew

8.6

Boarding

8.1

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Pittsburgh to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Pittsburgh to Missouri?

    Located just 13.5 mi from the city center, Pittsburgh (PIT) is the airport most travelers will use when flying to Missouri from Pittsburgh.

  • How popular is this Pittsburgh to Missouri flight route?

    The Pittsburgh to Missouri flight path was viewed by 6 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Pittsburgh to Missouri?

    A quick flight from Pittsburgh to Missouri can take about 5h 02m. Delta provides one of the quickest options available for as low as $177. Pittsburgh and Missouri are separated by a distance of 552 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Pittsburgh to Missouri one-way?

    $89 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on Southwest and Spirit Airlines, with prices starting from $111 and $127, respectively.

  • What are the most popular routes from Pittsburgh to Missouri?

    When deciding which route to take from Pittsburgh to Missouri consider Pittsburgh - Kansas City, Pittsburgh - Lambert-St Louis or Pittsburgh - Springfield-Branson as they are the most popular.

  • What are the cheapest flights from Pittsburgh to Missouri?

    While on average a flight from Pittsburgh to Missouri is generally $401, our data shows the cheapest flight currently is $194. When looking at the most popular route, (Pittsburgh - Kansas City), you can expect to pay $231 for that flight.

  • Can I find deals for flights from Pittsburgh to Missouri that include hotel bookings?

    Yes. In addition to deals on Pittsburgh to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Pittsburgh to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Pittsburgh to Missouri.

  • Can I find deals for business class flights from Pittsburgh to Missouri?

    Yes. Cheapflights offers flight deals from Pittsburgh to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Pittsburgh to Missouri?

    Currently, December is the cheapest month in which you can book a flight from Pittsburgh to Missouri (average of $167). Flying from Pittsburgh to Missouri in July is currently the most expensive (average of $269). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Pittsburgh to Missouri

Discover the top 4 airlines that operate flights from Pittsburgh to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$171Average$347FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$243Average$376FlexibilityNo cancel feeOn-time63%
DeltaCheapest$248Average$404FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$258Average$419FlexibilityNo cancel feeOn-time69%

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