$101+ Cheap flights from Pittsburgh (PIT) to Missouri
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/21. Fares are subject to change and may not be available on all flights or dates of travel.
PIT — STL
Oct 23 — Oct 301
Round-trip
1 adult, Economy
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Find cheap flights from Pittsburgh to Missouri with Cheapflights
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Cheapest flights from Pittsburgh to MissouriExplore the most affordable flight options available from Pittsburgh to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 23, 2026.
Explore the most affordable flight options available from Pittsburgh to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 23, 2026.
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:20 pm -
Nonstop1h 40m
Wed 10/216:30 pm -
Nonstop1h 40m
Deal found 9/20![Southwest logo]()
$227
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:30 pm -
Nonstop1h 55m
Thu 11/57:55 pm -
Nonstop1h 40m
Deal found 9/22![Southwest logo]()
$241
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:50 am -
Nonstop1h 55m
Wed 11/1110:55 am -
2 stops6h 00m
Deal found 9/21![Southwest logo]()
$242
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/283:47 pm -
1 stop6h 59m
Sat 10/317:29 am -
1 stop6h 38m
Deal found 9/18![American Airlines logo]()
$247
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:35 am -
2 stops8h 50m
Sat 11/1410:35 am -
Nonstop1h 35m
Deal found 9/22![Southwest logo]()
$256
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/144:40 pm -
1 stop6h 50m
Fri 10/167:55 pm -
Nonstop1h 40m
Deal found 9/20![Southwest logo]()
$257
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:50 am -
1 stop6h 01m
Tue 10/206:47 am -
1 stop3h 48m
Deal found 9/22![Delta logo]()
$261
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:00 am -
1 stop9h 12m
Tue 10/276:45 pm -
1 stop4h 14m
Deal found 9/21![United Airlines logo]()
$274
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:37 pm -
1 stop8h 09m
Tue 10/275:30 am -
1 stop5h 58m
Deal found 9/19![American Airlines logo]()
$279
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/315:35 am -
2 stops6h 35m
Mon 11/210:25 am -
1 stop5h 45m
Deal found 9/22![Southwest logo]()
$284
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:18 pm -
1 stop5h 41m
Mon 10/196:39 pm -
1 stop4h 20m
Deal found 9/23![United Airlines logo]()
$314
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:15 pm -
1 stop3h 50m
Thu 10/221:50 pm -
1 stop7h 45m
Deal found 9/21![Southwest logo]()
$319
Best flights from Pittsburgh to MissouriDiscover carefully curated flight deals from Pittsburgh to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 23, 2026.
Discover carefully curated flight deals from Pittsburgh to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 23, 2026.
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:50 am -
Nonstop1h 55m
Tue 10/276:30 pm -
Nonstop1h 40m
Deal found 9/22![Southwest logo]()
$227
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:18 pm -
1 stop5h 41m
Mon 10/196:39 pm -
1 stop4h 20m
Deal found 9/23![United Airlines logo]()
$314
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:50 am -
1 stop6h 35m
Mon 11/95:18 pm -
1 stop6h 28m
Deal found 9/18![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:05 am -
1 stop4h 57m
Sat 11/217:32 am -
2 stops7h 13m
Deal found 9/22![American Airlines logo]()
$344
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:20 pm -
Nonstop1h 40m
Wed 10/215:30 am -
1 stop5h 25m
Deal found 9/20![Southwest logo]()
$237
This Southwest deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:50 am -
Nonstop1h 55m
Thu 10/295:40 pm -
1 stop4h 55m
Deal found 9/18![Southwest logo]()
$237
This Southwest deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:50 am -
Nonstop1h 55m
Mon 11/93:05 pm -
2 stops7h 50m
Deal found 9/18![Southwest logo]()
$242
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:05 am -
1 stop4h 56m
Mon 10/126:24 pm -
1 stop4h 19m
Deal found 9/23![American Airlines logo]()
$358
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:15 pm -
Nonstop1h 45m
Sun 11/86:40 am -
1 stop4h 10m
Deal found 9/21![Southwest logo]()
$277
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/97:25 pm -
1 stop4h 56m
Wed 2/1011:25 am -
1 stop4h 32m
Deal found 9/18![United Airlines logo]()
$379
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/93:30 pm -
1 stop7h 20m
Thu 11/1210:25 am -
1 stop5h 45m
Deal found 9/20![Southwest logo]()
$279
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/272:07 pm -
1 stop4h 23m
Sun 11/299:00 pm -
1 stop4h 31m
Deal found 9/20![United Airlines logo]()
$383
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1511:11 am -
1 stop4h 29m
Sun 10/186:00 am -
1 stop7h 14m
Deal found 9/21![Delta logo]()
$429
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:15 pm -
Nonstop1h 45m
Sun 10/185:55 am -
1 stop4h 00m
Deal found 9/21![Southwest logo]()
$287
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/92:07 pm -
1 stop4h 27m
Thu 11/126:00 am -
2 stops7h 14m
Deal found 9/23![United Airlines logo]()
$384
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2611:45 am -
2 stops6h 10m
Tue 12/16:20 am -
1 stop3h 20m
Deal found 9/21![Southwest logo]()
$298
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/96:30 am -
1 stop5h 07m
Tue 1/123:10 pm -
1 stop7h 45m
Deal found 9/20![United Airlines logo]()
$439
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:00 pm -
1 stop7h 30m
Mon 10/193:20 pm -
1 stop6h 20m
Deal found 9/19![Southwest logo]()
$314
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/142:37 pm -
2 stops7h 18m
Sun 10/186:00 am -
1 stop5h 28m
Deal found 9/21![American Airlines logo]()
$603
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:35 am -
1 stop6h 35m
Tue 11/246:05 pm -
1 stop3h 30m
Deal found 9/20![Southwest logo]()
$335
This Southwest deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/51:10 pm -
2 stops7h 35m
Sat 12/121:30 pm -
2 stops7h 05m
Deal found 9/23![Southwest logo]()
$341
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:11 am -
1 stop6h 28m
Mon 10/123:43 pm -
2 stops6h 47m
Deal found 9/23![United Airlines logo]()
$551
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:50 am -
Nonstop1h 55m
Sun 10/258:00 pm -
Nonstop1h 40m
Deal found 9/21![Southwest logo]()
$356
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/116:10 am -
1 stop8h 25m
Wed 10/144:35 pm -
1 stop3h 35m
Deal found 9/19![Southwest logo]()
$358
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:46 pm -
1 stop4h 09m
Fri 10/911:15 am -
1 stop20h 23m
Deal found 9/19![United Airlines logo]()
$697
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/118:00 pm -
1 stop5h 30m
Sun 12/136:45 am -
1 stop8h 30m
Deal found 9/22![Southwest logo]()
$383
Last-minute flights from Pittsburgh to MissouriDiscover last-minute flight deals from Pittsburgh to Missouri. Data last updated September 23, 2026 and is based on user searches.
Discover last-minute flight deals from Pittsburgh to Missouri. Data last updated September 23, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:50 am -
1 stop6h 01m
Tue 10/206:47 am -
1 stop3h 48m
Deal found 9/22![Delta logo]()
$261
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/144:40 pm -
1 stop6h 50m
Fri 10/167:55 pm -
Nonstop1h 40m
Deal found 9/20![Southwest logo]()
$257
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:00 pm -
1 stop7h 30m
Mon 10/193:20 pm -
1 stop6h 20m
Deal found 9/21![Southwest logo]()
$314
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:20 pm -
Nonstop1h 40m
Wed 10/216:30 pm -
Nonstop1h 40m
Deal found 9/20![Southwest logo]()
$227
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:15 pm -
Nonstop1h 45m
Tue 10/278:30 am -
2 stops7h 30m
Deal found 9/22![Southwest logo]()
$242
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:50 am -
Nonstop1h 55m
Fri 10/237:55 pm -
Nonstop1h 40m
Deal found 9/22![Southwest logo]()
$268
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:37 pm -
1 stop8h 09m
Tue 10/275:30 am -
1 stop5h 58m
Deal found 9/19![American Airlines logo]()
$279
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:50 am -
Nonstop1h 55m
Sun 10/255:45 am -
1 stop3h 35m
Deal found 9/21![Southwest logo]()
$277
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:00 am -
1 stop9h 12m
Tue 10/276:45 pm -
1 stop4h 14m
Deal found 9/21![United Airlines logo]()
$274
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/283:47 pm -
1 stop6h 59m
Sat 10/317:29 am -
1 stop6h 38m
Deal found 9/18![American Airlines logo]()
$247
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:20 pm -
Nonstop1h 40m
Sun 11/110:15 am -
Nonstop1h 35m
Deal found 9/20![Southwest logo]()
$267
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/315:35 am -
2 stops6h 35m
Mon 11/210:25 am -
1 stop5h 45m
Deal found 9/22![Southwest logo]()
$284
One-way flights from Pittsburgh to MissouriSearch for one-way flight options from Pittsburgh to Missouri. Find affordable one-way fares based on user searches. Data last updated September 23, 2026.
Search for one-way flight options from Pittsburgh to Missouri. Find affordable one-way fares based on user searches. Data last updated September 23, 2026.
This Frontier deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:59 pm -
1 stop6h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Frontier logo]()
$101
This Frontier deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1911:43 am -
1 stop12h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Frontier logo]()
$107
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:05 pm -
Nonstop1h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Southwest logo]()
$114
This Frontier deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/226:59 pm -
1 stop6h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Frontier logo]()
$117
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:00 am -
Nonstop2h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Southwest logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:30 am -
2 stops36h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Multiple Airlines logo]()
$122
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/175:50 am -
1 stop6h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Delta logo]()
$124
This CheapOair deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/187:51 pm -
1 stop28h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Frontier logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/108:15 am -
3 stops34h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$126
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:40 am -
2 stops5h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Southwest logo]()
$129
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/217:59 pm -
1 stop4h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![Delta logo]()
$131
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:06 pm -
1 stop6h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![United Airlines logo]()
$140
Find flight deals from Pittsburgh to Missouri
Keep the following information in mind while searching for Pittsburgh to Missouri flight deals. Data was last updated September 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $227 (Southwest) |
One-way from | $101 (Frontier) |
Popular in | June |
Cheapest in | November |
Average price | $381 |
Good round-trip deal | $318 or less |
Good one-way deal | $217 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Pittsburgh to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 23, 2026.
Use the filters below to find and compare flights from Pittsburgh to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PittsburghSt. Louis
PIT Pittsburgh - STL Lambert-St Louis
PITSTL
Pittsburgh
Wed 11/18
6:50 am-7:45 am
Nonstop1h 55m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$114
Quickest round-trip
PittsburghSt. Louis
PIT Pittsburgh - STL Lambert-St Louis
PITSTL
Pittsburgh
Sat 11/7
1:10 pm-2:00 pm
Nonstop1h 50m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$114
PittsburghSt. Louis
PIT Pittsburgh - STL Lambert-St Louis
PITSTL
Pittsburgh
Wed 10/21
5:03 pm-9:13 pm
1 stop5h 10m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$124
PittsburghSt. Louis
PIT Pittsburgh - STL Lambert-St Louis
PITSTL
Pittsburgh
Sat 11/7
6:30 am-12:12 pm
1 stop6h 42m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$124
PittsburghSt. Louis
PIT Pittsburgh - STL Lambert-St Louis
PITSTL
Pittsburgh
Sat 10/24
5:50 am-9:42 am
1 stop4h 52m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$124
PittsburghSt. Louis
PIT Pittsburgh - STL Lambert-St Louis
PITSTL
Pittsburgh
Sat 10/17
7:45 am-1:20 pm
1 stop6h 35m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$124
PittsburghSt. Louis
PIT Pittsburgh - STL Lambert-St Louis
PITSTL
Pittsburgh
Thu 10/22
5:50 am-10:51 am
1 stop6h 01m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$124
PittsburghSt. Louis
PIT Pittsburgh - STL Lambert-St Louis
PITSTL
Pittsburgh
Tue 11/17
8:00 am-1:23 pm
1 stop6h 23m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$124
PittsburghSt. Louis
PIT Pittsburgh - STL Lambert-St Louis
PITSTL
Pittsburgh
Mon 11/16
3:14 pm-9:42 pm
1 stop7h 28m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$124
PittsburghSt. Louis
PIT Pittsburgh - STL Lambert-St Louis
PITSTL
Pittsburgh
Wed 11/18
1:39 pm-6:13 pm
1 stop5h 34m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$124
Showing 1-10 of 49 resultsSorted by cheapest first
Best time to book a flight from Pittsburgh to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Pittsburgh with our price prediction graph.
PIT-STL
PIT-MCI
PIT-SGF
PIT-COU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Pittsburgh to Missouri
PIT-USMO
PIT-STL
PIT-MCI
PIT-SGF
PIT-COU
What is the cheapest month to book a flight from Pittsburgh to Missouri?
Currently, January is the cheapest month in which you can book a flight from Pittsburgh to Missouri (average of $307). Flying from Pittsburgh to Missouri in June is currently the most expensive (average of $509). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PIT to MO?
Find hourly flight availability from Pittsburgh to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 23, 2026.
It’s optimal to fly from Pittsburgh to Missouri at noon. By choosing this option you can save up to 18% on the cost of your flight, compared to a flight in the morning.
How much does it cost to fly round-trip from Pittsburgh to Missouri?
Airfare is below average for this route at the moment.
Pittsburgh to Missouri flights typically cost between $244 and $460 in October.The cheapest round-trip price found within the last 5 days was $227 on Southwest (Oct 19-Oct 21).
How far ahead should I book a flight from Pittsburgh to Missouri?
The best time to book flights from Pittsburgh to Missouri is 28 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated September 23, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Pittsburgh to Missouri by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Crew
8.6
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Food
7.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Crew
8.6
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Food
7.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Crew
8.6
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Food
7.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Crew
8.6
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Food
7.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Crew
8.6
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Related info for your journey
Find useful and relevant information for your journey from Pittsburgh to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Pittsburgh to Missouri
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Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Pittsburgh to Missouri by cabin class
Find flights from Pittsburgh to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Pittsburgh and Missouri flights
Browse other Pittsburgh and Missouri flight options. Last updated on September 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Pittsburgh to Missouri flights
Consider these flights traveling from Pittsburgh to Missouri.
Top 4 airlines flying from Pittsburgh to Missouri
Discover the top 4 airlines that operate flights from Pittsburgh to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$158 | Average$404 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$188 | Average$413 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$217 | Average$409 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$263 | Average$427 | FlexibilityNo cancel fee | On-time69% |