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$79+ Cheap flights from Pittsburgh (PIT) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/21. Fares are subject to change and may not be available on all flights or dates of travel.
PIT — STL
Feb 20 — Feb 271
Fri 2/20
Fri 2/27
1 adult, Economy
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Cheap flight deals from Pittsburgh to Missouri

Cheapest flights from Pittsburgh to Missouri
Explore the most affordable flight options available from Pittsburgh to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/215:45 pm
PIT
-
STL
1 stop7h 14m
Multiple Airlines
Wed 2/253:49 pm
STL
-
PIT
1 stop6h 36m
Multiple Airlines
Deal found 1/20$149
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/175:45 pm
PIT
-
STL
2 stops14h 06m
Multiple Airlines
Tue 2/243:49 pm
STL
-
PIT
1 stop6h 36m
Multiple Airlines
Deal found 1/20$177
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/241:42 pm
PIT
-
STL
1 stop5h 11m
Delta
Sat 3/2810:50 am
STL
-
PIT
1 stop5h 30m
Delta
Deal found 1/21$196
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/304:29 pm
PIT
-
STL
2 stops19h 42m
Multiple Airlines
Tue 2/243:49 pm
STL
-
PIT
1 stop6h 36m
Multiple Airlines
Deal found 1/20$207
This Southwest deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/126:50 am
PIT
-
STL
Nonstop1h 55m
Southwest
Mon 3/164:45 pm
STL
-
PIT
1 stop5h 55m
Southwest
Deal found 1/18$213
This Southwest deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/2412:30 pm
PIT
-
STL
Nonstop2h 00m
Southwest
Sat 2/286:10 am
STL
-
PIT
1 stop5h 40m
Southwest
Deal found 1/20$241
This Southwest deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1012:30 pm
PIT
-
STL
Nonstop2h 00m
Southwest
Wed 2/116:20 am
STL
-
PIT
1 stop9h 00m
Southwest
Deal found 1/19$251
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/205:45 am
PIT
-
STL
1 stop19h 42m
Multiple Airlines
Fri 2/278:22 pm
STL
-
PIT
2 stops15h 13m
Multiple Airlines
Deal found 1/20$254
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2410:45 am
PIT
-
MCI
1 stop24h 38m
Spirit Airlines
Fri 3/2711:26 am
MCI
-
PIT
1 stop21h 12m
Spirit Airlines
Deal found 1/20$254
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/165:45 pm
PIT
-
MCI
1 stop22h 44m
Spirit Airlines
Fri 2/2011:26 am
MCI
-
PIT
1 stop7h 48m
Spirit Airlines
Deal found 1/20$256
This Booking.com deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/274:14 pm
PIT
-
MCI
1 stop28h 32m
Multiple Airlines
Mon 3/211:26 am
MCI
-
PIT
1 stop11h 33m
Multiple Airlines
Deal found 1/21$260
This Kiwi.com deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/56:00 am
PIT
-
MCI
2 stops30h 50m
Multiple Airlines
Mon 2/911:26 am
MCI
-
PIT
1 stop21h 14m
Multiple Airlines
Deal found 1/21$261

Find flight deals from Pittsburgh to Missouri

Keep the following information in mind while searching for Pittsburgh to Missouri flight deals. Data was last updated January 21, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$149
(Kiwi.com)

One-way from

$79
(Kiwi.com)

Popular in

January

Cheapest in

April

Average price

$427

Good round-trip deal

$331 or less

Good one-way deal

$216 or less
Provider with most accurate pricing for Pittsburgh-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Pittsburgh-Lambert-St Louis flights.
Search Deals
From Pittsburgh to Missouri
Search Deals
One-way flight from Pittsburgh to Missouri
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($34 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals
Price to beat on a round-trip flight from Pittsburgh to Missouri.
Search Deals
Price to beat on a one-way flight from Pittsburgh to Missouri.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Pittsburgh to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from Pittsburgh to Missouri that are best for you.

Fly from

Pittsburgh

Fly to

Missouri

Route

Depart

Return

Price

PittsburghSt. Louis

PIT - STL

PITSTL

Pittsburgh

Tue 3/24

1:42 pm-5:53 pm

1 stop5h 11m

Lambert-St Louis

Sat 3/28

10:50 am-5:20 pm

1 stop5h 30m

$196

PittsburghSt. Louis

PIT - STL

PITSTL

Pittsburgh

Tue 3/31

5:55 pm-9:57 pm

1 stop5h 02m

Lambert-St Louis

Sat 4/4

7:45 am-1:05 pm

1 stop4h 20m

$213

PittsburghSt. Louis

PIT - STL

PITSTL

Pittsburgh

Thu 3/12

5:20 am-10:45 am

1 stop6h 25m

Lambert-St Louis

Mon 3/16

4:45 pm-11:40 pm

1 stop5h 55m

$213

PittsburghSt. Louis

PIT - STL

PITSTL

Pittsburgh

Tue 2/10

8:56 am-2:30 pm

1 stop6h 34m

Lambert-St Louis

Wed 2/11

8:30 am-2:04 pm

1 stop4h 34m

$213

PittsburghSt. Louis

PIT - STL

PITSTL

Pittsburgh

Tue 2/10

12:30 pm-1:30 pm

Nonstop2h 00m

Lambert-St Louis

Wed 2/11

6:20 am-4:20 pm

1 stop9h 00m

$251

PittsburghKansas City

PIT - MCI

PITMCI

Pittsburgh

Mon 2/16

5:45 pm-3:29 pm

1 stop22h 44m

Kansas City

Fri 2/20

11:26 am-8:14 pm

1 stop7h 48m

$256

PittsburghSt. Louis

PIT - STL

PITSTL

Pittsburgh

Tue 2/24

10:35 am-8:35 pm

2 stops11h 00m

Lambert-St Louis

Sat 2/28

5:30 am-1:20 pm

1 stop6h 50m

$256

PittsburghSt. Louis

PIT - STL

PITSTL

Pittsburgh

Fri 2/27

7:30 am-12:27 am

1 stop17h 57m

Lambert-St Louis

Mon 3/2

8:22 pm-11:59 pm

2 stops26h 37m

$259

PittsburghKansas City

PIT - MCI

PITMCI

Pittsburgh

Fri 2/27

4:14 pm-7:46 pm

1 stop28h 32m

Kansas City

Mon 3/2

11:26 am-11:59 pm

1 stop11h 33m

$260

PittsburghSt. Louis

PIT - STL

PITSTL

Pittsburgh

Wed 2/25

5:56 pm-9:40 pm

1 stop4h 44m

Lambert-St Louis

Fri 2/27

7:41 am-1:09 pm

1 stop4h 28m

$262

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Showing 1-10 of 45 results
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Best time to book a flight from Pittsburgh to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Pittsburgh with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Pittsburgh to Missouri

What is the cheapest month to book a flight from Pittsburgh to Missouri?

Currently, November is the cheapest month in which you can book a flight from Pittsburgh to Missouri (average of $156). Flying from Pittsburgh to Missouri in July is currently the most expensive (average of $269). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PIT to MO?

Find hourly flight availability from Pittsburgh to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 21, 2026.

It’s optimal to fly from Pittsburgh to Missouri at noon. By choosing this option you can save up to 24% on the cost of your flight, compared to a flight in the morning.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated January 21, 2026.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Pittsburgh to Missouri by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,266 reviews

Overall

8.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,266 reviews
Southwest
8.0
Very good
4,266 reviews

Overall

8.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,089 reviews
Southwest
8.0
Very good
4,266 reviews

Overall

8.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,191 reviews
Southwest
8.0
Very good
4,266 reviews

Overall

8.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,174 reviews
Southwest
8.0
Very good
4,266 reviews

Overall

8.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Pittsburgh to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Pittsburgh to Missouri?

    Located just 13.5 mi from the city center, Pittsburgh (PIT) is the airport most travelers will use when flying to Missouri from Pittsburgh.

  • How popular is this Pittsburgh to Missouri flight route?

    The Pittsburgh to Missouri flight path was viewed by 6 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Pittsburgh to Missouri?

    A quick flight from Pittsburgh to Missouri can take about 5h 02m. Delta provides one of the quickest options available for as low as $213. Pittsburgh and Missouri are separated by a distance of 552 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Pittsburgh to Missouri one-way?

    $96 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on Southwest and Delta, with prices starting from $121 and $122, respectively.

  • What are the most popular routes from Pittsburgh to Missouri?

    When deciding which route to take from Pittsburgh to Missouri consider Pittsburgh - Lambert-St Louis, Pittsburgh - Kansas City or Pittsburgh - Springfield-Branson as they are the most popular.

  • What are the cheapest flights from Pittsburgh to Missouri?

    While on average a flight from Pittsburgh to Missouri is generally $334, our data shows the cheapest flight currently is $87. When looking at the most popular route, (Pittsburgh - Lambert-St Louis), you can expect to pay $149 for that flight.

  • Can I find deals for flights from Pittsburgh to Missouri that include hotel bookings?

    Yes. In addition to deals on Pittsburgh to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Pittsburgh to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Pittsburgh to Missouri.

  • Can I find deals for business class flights from Pittsburgh to Missouri?

    Yes. Cheapflights offers flight deals from Pittsburgh to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Pittsburgh to Missouri?

    Currently, November is the cheapest month in which you can book a flight from Pittsburgh to Missouri (average of $156). Flying from Pittsburgh to Missouri in July is currently the most expensive (average of $269). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Pittsburgh to Missouri

Discover the top 4 airlines that operate flights from Pittsburgh to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$170Average$350FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$241Average$383FlexibilityNo cancel feeOn-time63%
DeltaCheapest$248Average$377FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$277Average$402FlexibilityNo cancel feeOn-time69%

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