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$76+ Cheap flights from Pittsburgh (PIT) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/18. Fares are subject to change and may not be available on all flights or dates of travel.
PIT — STL
Apr 21 — Apr 281
Tue 4/21
Tue 4/28
1 adult, Economy
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Cheap flight deals from Pittsburgh to Missouri

Cheapest flights from Pittsburgh to Missouri
Explore the most affordable flight options available from Pittsburgh to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 22, 2026.

This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:50 am
PIT
-
STL
Nonstop1h 50m
Southwest
Tue 4/2110:15 am
STL
-
PIT
Nonstop1h 40m
Southwest
Deal found 3/19$217
This Delta deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:40 am
PIT
-
STL
1 stop4h 02m
Delta
Tue 5/56:48 am
STL
-
PIT
1 stop5h 34m
Delta
Deal found 3/20$237
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/289:25 am
PIT
-
STL
2 stops10h 30m
Southwest
Sat 5/302:05 pm
STL
-
PIT
1 stop3h 15m
Southwest
Deal found 3/21$248
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:50 am
PIT
-
STL
Nonstop1h 50m
Southwest
Sun 5/3110:15 am
STL
-
PIT
1 stop3h 50m
Southwest
Deal found 3/21$258
This Southwest deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/244:20 pm
PIT
-
STL
1 stop8h 20m
Southwest
Mon 4/277:40 pm
STL
-
PIT
Nonstop1h 35m
Southwest
Deal found 3/17$262
This Southwest deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:00 am
PIT
-
STL
1 stop5h 50m
Southwest
Mon 4/137:40 pm
STL
-
PIT
Nonstop1h 35m
Southwest
Deal found 3/17$266
This Southwest deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:55 am
PIT
-
STL
Nonstop1h 50m
Southwest
Mon 6/154:35 pm
STL
-
PIT
2 stops5h 55m
Southwest
Deal found 3/17$267
This Southwest deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/810:15 am
PIT
-
STL
2 stops9h 15m
Southwest
Wed 6/103:15 pm
STL
-
PIT
2 stops6h 10m
Southwest
Deal found 3/17$271
This Delta deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:40 am
PIT
-
STL
1 stop4h 02m
Delta
Sun 4/196:48 am
STL
-
PIT
1 stop5h 39m
Delta
Deal found 3/20$272
This Southwest deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/297:10 pm
PIT
-
MCI
1 stop4h 20m
Southwest
Sat 5/211:15 am
MCI
-
PIT
1 stop4h 50m
Southwest
Deal found 3/20$304
This Southwest deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:50 pm
PIT
-
MCI
1 stop6h 00m
Southwest
Sat 4/253:10 pm
MCI
-
PIT
1 stop5h 20m
Southwest
Deal found 3/20$321
This Delta deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:00 am
PIT
-
SGF
1 stop6h 01m
Delta
Tue 9/156:00 am
SGF
-
PIT
1 stop5h 54m
Delta
Deal found 3/20$329

Find flight deals from Pittsburgh to Missouri

Keep the following information in mind while searching for Pittsburgh to Missouri flight deals. Data was last updated March 22, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$217
(Southwest)

One-way from

$76
(Frontier)

Popular in

October

Cheapest in

November

Average price

$387

Good round-trip deal

$344 or less

Good one-way deal

$158 or less
Provider with most accurate pricing for Pittsburgh-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Pittsburgh-Lambert-St Louis flights.
Search Deals
From Pittsburgh to Missouri
Search Deals
One-way flight from Pittsburgh to Missouri
Search Deals
Highest demand for flights based on searches. 0% potential increase in price ($2 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($4 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals
Price to beat on a round-trip flight from Pittsburgh to Missouri.
Search Deals
Price to beat on a one-way flight from Pittsburgh to Missouri.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Pittsburgh to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
Use the filters below to find and compare flights from Pittsburgh to Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

PittsburghSt. Louis

PIT - STL

PITSTL

Pittsburgh

Mon 6/8

8:15 pm-9:00 pm

Nonstop1h 45m

Lambert-St Louis

Wed 6/10

10:25 am-1:00 pm

Nonstop1h 35m

$217

PittsburghSt. Louis

PIT - STL

PITSTL

Pittsburgh

Thu 5/28

8:05 pm-8:55 pm

Nonstop1h 50m

Lambert-St Louis

Sat 5/30

6:55 pm-9:30 pm

Nonstop1h 35m

$217

PittsburghSt. Louis

PIT - STL

PITSTL

Pittsburgh

Mon 4/13

6:55 am-7:45 am

Nonstop1h 50m

Lambert-St Louis

Wed 4/15

3:55 pm-8:45 pm

1 stop3h 50m

$227

PittsburghSt. Louis

PIT - STL

PITSTL

Pittsburgh

Thu 4/16

8:10 pm-11:15 pm

1 stop4h 05m

Lambert-St Louis

Tue 4/21

10:15 am-12:55 pm

Nonstop1h 40m

$227

PittsburghSt. Louis

PIT - STL

PITSTL

Pittsburgh

Wed 4/8

6:05 am-1:00 pm

2 stops7h 55m

Lambert-St Louis

Thu 4/9

10:15 am-12:55 pm

Nonstop1h 40m

$232

PittsburghSt. Louis

PIT - STL

PITSTL

Pittsburgh

Tue 4/28

6:05 am-1:00 pm

2 stops7h 55m

Lambert-St Louis

Wed 4/29

6:45 pm-9:20 pm

Nonstop1h 35m

$232

PittsburghSt. Louis

PIT - STL

PITSTL

Pittsburgh

Thu 5/28

6:49 am-10:34 am

1 stop4h 45m

Lambert-St Louis

Sat 5/30

7:22 am-1:09 pm

1 stop4h 47m

$237

PittsburghSt. Louis

PIT - STL

PITSTL

Pittsburgh

Wed 4/15

6:05 am-1:00 pm

2 stops7h 55m

Lambert-St Louis

Tue 4/21

1:45 pm-8:45 pm

1 stop6h 00m

$242

PittsburghSt. Louis

PIT - STL

PITSTL

Pittsburgh

Fri 4/10

8:00 pm-10:45 pm

1 stop3h 45m

Lambert-St Louis

Tue 5/12

6:45 pm-9:20 pm

Nonstop1h 35m

$266

PittsburghKansas City

PIT - MCI

PITMCI

Pittsburgh

Thu 5/28

10:54 am-2:20 pm

1 stop4h 26m

Kansas City

Thu 6/4

6:00 am-1:09 pm

1 stop6h 09m

$321

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/20

Showing 1-10 of 54 resultsSorted by cheapest first
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6

Best time to book a flight from Pittsburgh to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Pittsburgh with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Pittsburgh to Missouri

What is the cheapest month to book a flight from Pittsburgh to Missouri?

Currently, November is the cheapest month in which you can book a flight from Pittsburgh to Missouri (average of $156). Flying from Pittsburgh to Missouri in March is currently the most expensive (average of $282). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PIT to MO?

Find hourly flight availability from Pittsburgh to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 22, 2026.

It’s optimal to fly from Pittsburgh to Missouri at noon. By choosing this option you can save up to 27% on the cost of your flight, compared to a flight in the morning.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated March 22, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Pittsburgh to Missouri by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,324 reviews

Boarding

8.1

Food

7.0

Crew

8.6

Overall

8.0

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Southwest
8.0
Very good
4,324 reviews
Southwest
8.0
Very good
4,324 reviews

Boarding

8.1

Food

7.0

Crew

8.6

Overall

8.0

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Delta
7.9
Good
8,314 reviews
Southwest
8.0
Very good
4,324 reviews

Boarding

8.1

Food

7.0

Crew

8.6

Overall

8.0

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
United Airlines
7.4
Good
9,455 reviews
Southwest
8.0
Very good
4,324 reviews

Boarding

8.1

Food

7.0

Crew

8.6

Overall

8.0

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
American Airlines
7.1
Good
11,489 reviews
Southwest
8.0
Very good
4,324 reviews

Boarding

8.1

Food

7.0

Crew

8.6

Overall

8.0

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from Pittsburgh to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Pittsburgh to Missouri?

    Located just 13.5 mi from the city center, Pittsburgh (PIT) is the airport most travelers will use when flying to Missouri from Pittsburgh.

  • How popular is this Pittsburgh to Missouri flight route?

    The Pittsburgh to Missouri flight path was viewed by 8 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Pittsburgh to Missouri?

    A quick flight from Pittsburgh to Missouri can take about 1h 45m. Southwest provides one of the quickest options available for as low as $217. Pittsburgh and Missouri are separated by a distance of 552 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Pittsburgh to Missouri one-way?

    $96 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on Southwest and Delta, with prices starting from $121 and $122, respectively.

  • What are the most popular routes from Pittsburgh to Missouri?

    When deciding which route to take from Pittsburgh to Missouri consider Pittsburgh - Lambert-St Louis, Pittsburgh - Kansas City or Pittsburgh - Springfield-Branson as they are the most popular.

  • What are the cheapest flights from Pittsburgh to Missouri?

    While on average a flight from Pittsburgh to Missouri is generally $326, our data shows the cheapest flight currently is $132. When looking at the most popular route, (Pittsburgh - Lambert-St Louis), you can expect to pay $217 for that flight.

  • Can I find deals for flights from Pittsburgh to Missouri that include hotel bookings?

    Yes. In addition to deals on Pittsburgh to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Pittsburgh to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Pittsburgh to Missouri.

  • Can I find deals for business class flights from Pittsburgh to Missouri?

    Yes. Cheapflights offers flight deals from Pittsburgh to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Pittsburgh to Missouri?

    Currently, November is the cheapest month in which you can book a flight from Pittsburgh to Missouri (average of $156). Flying from Pittsburgh to Missouri in March is currently the most expensive (average of $282). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Pittsburgh to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Pittsburgh to Missouri

Discover the top 4 airlines that operate flights from Pittsburgh to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$170Average$348FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$235Average$380FlexibilityNo cancel feeOn-time63%
DeltaCheapest$248Average$432FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$277Average$425FlexibilityNo cancel feeOn-time69%

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