$96+ Cheap flights from Pittsburgh (PIT) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/25. Fares are subject to change and may not be available on all flights or dates of travel.
PIT — STL
May 9 — May 161
Round-trip
1 adult, Economy
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Find cheap flights from Pittsburgh to Missouri with Cheapflights
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Cheapest flights from Pittsburgh to MissouriExplore the most affordable flight options available from Pittsburgh to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 9, 2026.
Explore the most affordable flight options available from Pittsburgh to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 9, 2026.
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/297:05 am
PIT
- STL
1 stop5h 51m
Delta
Tue 5/126:04 pm
STL
- PIT
1 stop3h 34m
Delta
Deal found 4/7![Delta logo]()
$201
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:00 am
PIT
- STL
1 stop5h 34m
Delta
Tue 5/51:46 pm
STL
- PIT
1 stop4h 18m
Delta
Deal found 4/7![Delta logo]()
$211
This Southwest deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:50 am
PIT
- STL
Nonstop1h 50m
Southwest
Tue 5/56:45 pm
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 4/4![Southwest logo]()
$217
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:52 am
PIT
- STL
1 stop6h 28m
Delta
Mon 5/256:45 am
STL
- PIT
1 stop3h 28m
Delta
Deal found 4/4![Delta logo]()
$237
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/197:10 pm
PIT
- STL
Nonstop1h 50m
Southwest
Sat 5/236:55 pm
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 4/5![Southwest logo]()
$241
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/23:56 pm
PIT
- STL
1 stop8h 58m
American Airlines
Tue 6/97:00 am
STL
- PIT
1 stop7h 09m
American Airlines
Deal found 4/8![American Airlines logo]()
$243
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:50 am
PIT
- STL
Nonstop1h 50m
Southwest
Sat 5/166:20 am
STL
- PIT
1 stop4h 10m
Southwest
Deal found 4/9![Southwest logo]()
$246
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:55 pm
PIT
- STL
1 stop4h 05m
Southwest
Tue 5/126:45 pm
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 4/7![Southwest logo]()
$247
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:10 pm
PIT
- STL
1 stop6h 15m
Southwest
Mon 5/257:40 pm
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 4/5![Southwest logo]()
$248
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/123:50 pm
PIT
- MCI
1 stop7h 50m
Southwest
Tue 5/193:30 pm
MCI
- PIT
1 stop4h 15m
Southwest
Deal found 4/6![Southwest logo]()
$307
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/210:45 am
PIT
- MCI
1 stop9h 55m
Southwest
Tue 5/54:50 pm
MCI
- PIT
1 stop3h 30m
Southwest
Deal found 4/7![Southwest logo]()
$314
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/279:25 am
PIT
- MCI
1 stop6h 10m
Southwest
Tue 5/52:10 pm
MCI
- PIT
2 stops5h 35m
Southwest
Deal found 4/5![Southwest logo]()
$319
Best flights from Pittsburgh to MissouriDiscover carefully curated flight deals from Pittsburgh to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 9, 2026.
Discover carefully curated flight deals from Pittsburgh to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 9, 2026.
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:52 am
PIT
- STL
1 stop6h 28m
Delta
Mon 5/256:45 am
STL
- PIT
1 stop3h 28m
Delta
Deal found 4/4![Delta logo]()
$237
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/197:10 pm
PIT
- STL
Nonstop1h 50m
Southwest
Sat 5/236:55 pm
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 4/5![Southwest logo]()
$241
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/234:18 pm
PIT
- JLN
1 stop8h 26m
United Airlines
Mon 4/271:58 pm
JLN
- PIT
1 stop7h 52m
United Airlines
Deal found 4/8![United Airlines logo]()
$354
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:33 am
PIT
- SGF
1 stop5h 41m
American Airlines
Wed 5/135:19 am
SGF
- PIT
1 stop4h 45m
American Airlines
Deal found 4/8![American Airlines logo]()
$408
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:10 pm
PIT
- STL
Nonstop1h 50m
Southwest
Sun 5/1010:15 am
STL
- PIT
Nonstop1h 40m
Southwest
Deal found 4/5![Southwest logo]()
$247
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:00 am
PIT
- STL
1 stop5h 34m
Delta
Wed 5/66:50 pm
STL
- PIT
1 stop4h 44m
Delta
Deal found 4/6![Delta logo]()
$257
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:10 pm
PIT
- STL
1 stop6h 15m
Southwest
Mon 5/257:40 pm
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 4/5![Southwest logo]()
$248
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/27:05 am
PIT
- STL
1 stop4h 29m
Delta
Sun 5/36:50 pm
STL
- PIT
1 stop4h 45m
Delta
Deal found 4/5![Delta logo]()
$267
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/176:50 am
PIT
- STL
Nonstop1h 50m
Southwest
Wed 5/2010:15 am
STL
- PIT
Nonstop1h 40m
Southwest
Deal found 4/6![Southwest logo]()
$257
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:10 pm
PIT
- STL
Nonstop1h 50m
Southwest
Fri 5/87:40 pm
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 4/9![Southwest logo]()
$257
This United Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/55:58 pm
PIT
- SGF
1 stop5h 04m
United Airlines
Tue 5/126:00 am
SGF
- PIT
2 stops7h 02m
United Airlines
Deal found 4/7![United Airlines logo]()
$371
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/206:13 pm
PIT
- SGF
1 stop4h 57m
Delta
Mon 7/276:58 pm
SGF
- PIT
1 stop4h 52m
Delta
Deal found 4/6![Delta logo]()
$329
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/212:09 pm
PIT
- SGF
1 stop4h 15m
United Airlines
Sat 4/251:33 pm
SGF
- PIT
2 stops9h 20m
United Airlines
Deal found 4/6![United Airlines logo]()
$384
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/81:40 pm
PIT
- SGF
1 stop5h 26m
Delta
Fri 5/156:52 pm
SGF
- PIT
1 stop4h 53m
Delta
Deal found 4/5![Delta logo]()
$329
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:35 pm
PIT
- SGF
1 stop5h 21m
American Airlines
Sun 5/106:24 pm
SGF
- PIT
1 stop4h 59m
American Airlines
Deal found 4/8![American Airlines logo]()
$464
This United Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:47 pm
PIT
- MCI
1 stop4h 44m
United Airlines
Wed 5/64:15 pm
MCI
- PIT
1 stop6h 29m
United Airlines
Deal found 4/4![United Airlines logo]()
$387
This United Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:49 am
PIT
- MCI
1 stop4h 40m
United Airlines
Mon 5/256:36 pm
MCI
- PIT
1 stop4h 23m
United Airlines
Deal found 4/7![United Airlines logo]()
$396
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/78:10 pm
PIT
- MCI
1 stop4h 25m
Southwest
Sun 5/106:15 am
MCI
- PIT
1 stop4h 15m
Southwest
Deal found 4/7![Southwest logo]()
$364
This Delta deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:00 am
PIT
- MCI
1 stop6h 20m
Delta
Sun 5/35:46 pm
MCI
- PIT
1 stop4h 10m
Delta
Deal found 4/9![Delta logo]()
$374
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/288:54 am
PIT
- JLN
1 stop5h 43m
United Airlines
Sat 5/29:06 am
JLN
- PIT
2 stops13h 14m
United Airlines
Deal found 4/6![United Airlines logo]()
$414
This Southwest deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/221:35 pm
PIT
- MCI
1 stop6h 20m
Southwest
Sat 5/235:25 pm
MCI
- PIT
1 stop4h 35m
Southwest
Deal found 4/4![Southwest logo]()
$393
This United Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/277:00 am
PIT
- SGF
1 stop4h 48m
United Airlines
Sat 5/28:50 am
SGF
- PIT
2 stops13h 30m
United Airlines
Deal found 4/4![United Airlines logo]()
$414
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/309:25 am
PIT
- MCI
2 stops8h 45m
Southwest
Mon 5/45:35 pm
MCI
- PIT
1 stop4h 40m
Southwest
Deal found 4/5![Southwest logo]()
$397
This Delta deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:25 pm
PIT
- SGF
1 stop4h 54m
Delta
Sun 5/176:52 pm
SGF
- PIT
1 stop4h 53m
Delta
Deal found 4/9![Delta logo]()
$478
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/122:05 pm
PIT
- SGF
2 stops10h 37m
United Airlines
Tue 9/155:40 am
SGF
- PIT
2 stops8h 45m
United Airlines
Deal found 4/8![United Airlines logo]()
$439
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/248:40 am
PIT
- MCI
1 stop5h 45m
Southwest
Mon 9/286:15 am
MCI
- PIT
1 stop3h 30m
Southwest
Deal found 4/9![Southwest logo]()
$407
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2310:49 am
PIT
- SGF
1 stop7h 35m
United Airlines
Mon 4/276:50 pm
SGF
- PIT
1 stop4h 03m
United Airlines
Deal found 4/8![United Airlines logo]()
$439
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/106:10 am
PIT
- SGF
2 stops9h 25m
United Airlines
Sat 5/163:00 pm
SGF
- PIT
1 stop7h 44m
United Airlines
Deal found 4/8![United Airlines logo]()
$448
Last-minute flights from Pittsburgh to MissouriDiscover last-minute flight deals from Pittsburgh to Missouri. Data last updated April 9, 2026 and is based on user searches.
Discover last-minute flight deals from Pittsburgh to Missouri. Data last updated April 9, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/279:25 am
PIT
- MCI
1 stop6h 10m
Southwest
Tue 5/52:10 pm
MCI
- PIT
2 stops5h 35m
Southwest
Deal found 4/5![Southwest logo]()
$319
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/297:05 am
PIT
- STL
1 stop5h 51m
Delta
Tue 5/126:04 pm
STL
- PIT
1 stop3h 34m
Delta
Deal found 4/7![Delta logo]()
$201
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:00 am
PIT
- STL
1 stop5h 34m
Delta
Tue 5/51:46 pm
STL
- PIT
1 stop4h 18m
Delta
Deal found 4/7![Delta logo]()
$211
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/308:24 am
PIT
- STL
1 stop5h 24m
American Airlines
Tue 5/58:54 am
STL
- PIT
1 stop8h 38m
American Airlines
Deal found 4/8![American Airlines logo]()
$249
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/210:45 am
PIT
- MCI
1 stop9h 55m
Southwest
Tue 5/54:50 pm
MCI
- PIT
1 stop3h 30m
Southwest
Deal found 4/7![Southwest logo]()
$314
This Southwest deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:50 am
PIT
- STL
Nonstop1h 50m
Southwest
Tue 5/56:45 pm
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 4/4![Southwest logo]()
$217
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:55 pm
PIT
- STL
1 stop4h 05m
Southwest
Tue 5/126:45 pm
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 4/7![Southwest logo]()
$247
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/123:50 pm
PIT
- MCI
1 stop7h 50m
Southwest
Tue 5/193:30 pm
MCI
- PIT
1 stop4h 15m
Southwest
Deal found 4/6![Southwest logo]()
$307
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:50 am
PIT
- STL
Nonstop1h 50m
Southwest
Sat 5/166:20 am
STL
- PIT
1 stop4h 10m
Southwest
Deal found 4/9![Southwest logo]()
$246
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/197:10 pm
PIT
- STL
Nonstop1h 50m
Southwest
Sat 5/236:55 pm
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 4/5![Southwest logo]()
$241
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:52 am
PIT
- STL
1 stop6h 28m
Delta
Mon 5/256:45 am
STL
- PIT
1 stop3h 28m
Delta
Deal found 4/5![Delta logo]()
$237
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:10 pm
PIT
- STL
1 stop6h 15m
Southwest
Mon 5/257:40 pm
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 4/5![Southwest logo]()
$248
One-way flights from Pittsburgh to MissouriSearch for one-way flight options from Pittsburgh to Missouri. Find affordable one-way fares based on user searches. Data last updated April 9, 2026.
Search for one-way flight options from Pittsburgh to Missouri. Find affordable one-way fares based on user searches. Data last updated April 9, 2026.
This Frontier deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2512:44 pm
PIT
- STL
1 stop11h 35m
Frontier
Deal found 4/7![Frontier logo]()
$96
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2810:20 am
PIT
- STL
1 stop6h 12m
Delta
Deal found 4/7![Delta logo]()
$101
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/87:59 pm
PIT
- STL
1 stop4h 57m
Delta
Deal found 4/7![Delta logo]()
$106
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/88:15 pm
PIT
- STL
2 stops22h 15m
Frontier
Deal found 4/5![Frontier logo]()
$108
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:35 am
PIT
- STL
2 stops25h 15m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2010:25 am
PIT
- STL
2 stops45h 25m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:15 pm
PIT
- STL
2 stops37h 35m
Multiple Airlines
Deal found 4/5![Multiple Airlines logo]()
$113
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/78:15 pm
PIT
- STL
2 stops37h 40m
Frontier
Deal found 4/5![Frontier logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:35 am
PIT
- STL
2 stops28h 51m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$116
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:15 pm
PIT
- STL
2 stops13h 35m
Multiple Airlines
Deal found 4/5![Multiple Airlines logo]()
$117
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:10 pm
PIT
- STL
Nonstop1h 50m
Southwest
Deal found 4/7![Southwest logo]()
$119
This Trip.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2010:25 am
PIT
- STL
1 stop13h 54m
Frontier
Deal found 4/6![Frontier logo]()
$120
Find flight deals from Pittsburgh to Missouri
Keep the following information in mind while searching for Pittsburgh to Missouri flight deals. Data was last updated April 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $201 (Delta) |
One-way from | $96 (Frontier) |
Popular in | October |
Cheapest in | November |
Average price | $348 |
Good round-trip deal | $379 or less |
Good one-way deal | $134 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Pittsburgh to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 9, 2026.
Use the filters below to find and compare flights from Pittsburgh to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Thu 5/21
6:52 am-12:20 pm
1 stop6h 28m
Lambert-St Louis
Mon 5/25
6:45 am-11:13 am
1 stop3h 28m
$237
Quickest round-trip
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Tue 5/19
7:10 pm-8:00 pm
Nonstop1h 50m
Lambert-St Louis
Sat 5/23
6:55 pm-9:30 pm
Nonstop1h 35m
$241
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Tue 5/5
7:10 pm-8:00 pm
Nonstop1h 50m
Lambert-St Louis
Sun 5/10
10:15 am-12:55 pm
Nonstop1h 40m
$247
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Sat 5/23
5:10 pm-10:25 pm
1 stop6h 15m
Lambert-St Louis
Mon 5/25
7:40 pm-10:15 pm
Nonstop1h 35m
$248
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Wed 5/6
6:00 am-10:34 am
1 stop5h 34m
Lambert-St Louis
Wed 5/6
6:50 pm-12:34 am
1 stop4h 44m
$257
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Sun 5/17
6:50 am-7:40 am
Nonstop1h 50m
Lambert-St Louis
Wed 5/20
10:15 am-12:55 pm
Nonstop1h 40m
$257
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Wed 5/6
7:10 pm-8:00 pm
Nonstop1h 50m
Lambert-St Louis
Fri 5/8
7:40 pm-10:15 pm
Nonstop1h 35m
$257
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Sat 5/2
7:05 am-10:34 am
1 stop4h 29m
Lambert-St Louis
Sun 5/3
6:50 pm-12:35 am
1 stop4h 45m
$267
PittsburghSpringfield
PIT - SGF
PITSGF
Pittsburgh
Mon 7/20
6:13 pm-10:10 pm
1 stop4h 57m
Springfield-Branson
Mon 7/27
6:58 pm-12:50 am
1 stop4h 52m
$329
PittsburghSpringfield
PIT - SGF
PITSGF
Pittsburgh
Fri 5/8
1:40 pm-6:06 pm
1 stop5h 26m
Springfield-Branson
Fri 5/15
6:52 pm-12:45 am
1 stop4h 53m
$329
Showing 1-10 of 51 resultsSorted by cheapest first
Best time to book a flight from Pittsburgh to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Pittsburgh with our price prediction graph.
PIT-STL
PIT-JLN
PIT-SGF
PIT-MCI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Pittsburgh to Missouri
PIT-USMO
PIT-STL
PIT-JLN
PIT-SGF
PIT-MCI
What is the cheapest month to book a flight from Pittsburgh to Missouri?
Currently, November is the cheapest month in which you can book a flight from Pittsburgh to Missouri (average of $156). Flying from Pittsburgh to Missouri in March is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PIT to MO?
Find hourly flight availability from Pittsburgh to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 9, 2026.
It’s optimal to fly from Pittsburgh to Missouri at noon. By choosing this option you can save up to 28% on the cost of your flight, compared to a flight in the morning.
How much does it cost to fly round-trip from Pittsburgh to Missouri?
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated April 9, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Pittsburgh to Missouri by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Comfort
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Comfort
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Comfort
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Comfort
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Comfort
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Pittsburgh to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Pittsburgh to Missouri
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Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Pittsburgh to Missouri by cabin class
Find flights from Pittsburgh to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Pittsburgh and Missouri flights
Browse other Pittsburgh and Missouri flight options. Last updated on April 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Pittsburgh to Missouri flights
Consider these flights traveling from Pittsburgh to Missouri.
Top 4 airlines flying from Pittsburgh to Missouri
Discover the top 4 airlines that operate flights from Pittsburgh to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$170 | Average$349 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$221 | Average$379 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$248 | Average$415 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$277 | Average$427 | FlexibilityNo cancel fee | On-time69% |