$70+ Cheap flights from Pittsburgh (PIT) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/16. Fares are subject to change and may not be available on all flights or dates of travel.
PIT — STL
May 20 — May 271
Round-trip
1 adult, Economy
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Find cheap flights from Pittsburgh to Missouri with Cheapflights
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Cheapest flights from Pittsburgh to MissouriExplore the most affordable flight options available from Pittsburgh to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 20, 2026.
Explore the most affordable flight options available from Pittsburgh to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 20, 2026.
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:15 am
PIT
- STL
Nonstop1h 50m
Southwest
Mon 5/2510:15 am
STL
- PIT
Nonstop1h 40m
Southwest
Deal found 4/17![Southwest logo]()
$217
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/23:56 pm
PIT
- STL
1 stop8h 58m
American Airlines
Tue 6/97:00 am
STL
- PIT
1 stop7h 04m
American Airlines
Deal found 4/16![American Airlines logo]()
$223
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/233:56 pm
PIT
- STL
1 stop9h 00m
American Airlines
Mon 6/297:00 am
STL
- PIT
1 stop4h 33m
American Airlines
Deal found 4/16![American Airlines logo]()
$229
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:50 pm
PIT
- STL
1 stop5h 09m
Delta
Tue 6/96:10 pm
STL
- PIT
1 stop4h 57m
Delta
Deal found 4/16![Delta logo]()
$235
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:45 am
PIT
- STL
Nonstop1h 45m
Southwest
Wed 7/13:10 pm
STL
- PIT
1 stop6h 10m
Southwest
Deal found 4/16![Southwest logo]()
$236
This Southwest deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:55 am
PIT
- STL
2 stops8h 30m
Southwest
Tue 5/263:55 pm
STL
- PIT
1 stop6h 25m
Southwest
Deal found 4/18![Southwest logo]()
$240
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:55 am
PIT
- STL
Nonstop1h 50m
Southwest
Thu 5/147:40 pm
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 4/16![Southwest logo]()
$241
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:25 am
PIT
- STL
1 stop8h 55m
Southwest
Mon 5/257:40 pm
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 4/15![Southwest logo]()
$251
This Trip.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/19:59 am
PIT
- STL
1 stop14h 20m
Frontier
Sun 5/34:59 pm
STL
- PIT
1 stop15h 31m
Frontier
Deal found 4/15![Frontier logo]()
$253
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:50 pm
PIT
- STL
1 stop5h 09m
Delta
Mon 5/187:01 pm
STL
- PIT
1 stop4h 44m
Delta
Deal found 4/15![Delta logo]()
$255
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/412:04 pm
PIT
- MCI
2 stops30h 25m
Multiple Airlines
Mon 6/810:35 am
MCI
- PIT
1 stop7h 45m
Multiple Airlines
Deal found 4/18![Multiple Airlines logo]()
$256
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/78:15 pm
PIT
- MCI
1 stop14h 14m
Multiple Airlines
Wed 5/136:24 pm
MCI
- PIT
2 stops26h 43m
Multiple Airlines
Deal found 4/15![Multiple Airlines logo]()
$257
Best flights from Pittsburgh to MissouriDiscover carefully curated flight deals from Pittsburgh to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 20, 2026.
Discover carefully curated flight deals from Pittsburgh to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 20, 2026.
This Southwest deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:15 am
PIT
- STL
Nonstop1h 50m
Southwest
Mon 5/251:45 pm
STL
- PIT
1 stop6h 35m
Southwest
Deal found 4/19![Southwest logo]()
$226
This United Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:49 am
PIT
- STL
1 stop4h 45m
United Airlines
Wed 5/2711:25 am
STL
- PIT
1 stop4h 45m
United Airlines
Deal found 4/18![United Airlines logo]()
$235
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:37 pm
PIT
- STL
1 stop6h 22m
Delta
Mon 5/116:04 pm
STL
- PIT
1 stop3h 34m
Delta
Deal found 4/15![Delta logo]()
$235
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:25 am
PIT
- STL
1 stop8h 55m
Southwest
Mon 5/257:40 pm
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 4/15![Southwest logo]()
$251
This Delta deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/227:50 pm
PIT
- STL
1 stop5h 09m
Delta
Tue 5/266:45 am
STL
- PIT
1 stop3h 28m
Delta
Deal found 4/18![Delta logo]()
$302
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/127:59 pm
PIT
- STL
1 stop4h 57m
Delta
Mon 6/155:24 pm
STL
- PIT
1 stop6h 31m
Delta
Deal found 4/15![Delta logo]()
$302
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/28:45 am
PIT
- JLN
1 stop5h 52m
United Airlines
Wed 5/69:06 am
JLN
- PIT
1 stop5h 15m
United Airlines
Deal found 4/17![United Airlines logo]()
$334
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2411:45 am
PIT
- STL
1 stop5h 50m
Southwest
Tue 5/266:45 pm
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 4/15![Southwest logo]()
$305
This Delta deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:50 pm
PIT
- STL
1 stop5h 09m
Delta
Sat 5/167:05 pm
STL
- PIT
1 stop4h 40m
Delta
Deal found 4/18![Delta logo]()
$307
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:50 pm
PIT
- STL
1 stop5h 09m
Delta
Mon 5/187:01 pm
STL
- PIT
1 stop4h 44m
Delta
Deal found 4/17![Delta logo]()
$307
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:20 pm
PIT
- MCI
1 stop6h 39m
United Airlines
Wed 6/37:53 am
MCI
- PIT
1 stop4h 16m
United Airlines
Deal found 4/15![United Airlines logo]()
$394
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:25 am
PIT
- MCI
2 stops9h 10m
Southwest
Wed 5/202:10 pm
MCI
- PIT
2 stops5h 35m
Southwest
Deal found 4/15![Southwest logo]()
$373
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/127:00 am
PIT
- SGF
1 stop5h 01m
Delta
Tue 9/156:00 am
SGF
- PIT
1 stop5h 54m
Delta
Deal found 4/15![Delta logo]()
$329
This United Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:00 am
PIT
- MCI
1 stop7h 08m
United Airlines
Sat 5/161:50 pm
MCI
- PIT
2 stops9h 09m
United Airlines
Deal found 4/14![United Airlines logo]()
$399
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/26:15 am
PIT
- MCI
1 stop4h 45m
Southwest
Thu 8/66:15 am
MCI
- PIT
1 stop3h 30m
Southwest
Deal found 4/17![Southwest logo]()
$407
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/128:32 pm
PIT
- MCI
1 stop5h 05m
United Airlines
Sun 6/146:36 pm
MCI
- PIT
1 stop4h 23m
United Airlines
Deal found 4/16![United Airlines logo]()
$407
This United Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/292:05 pm
PIT
- SGF
1 stop4h 55m
United Airlines
Wed 9/25:00 pm
SGF
- PIT
1 stop5h 49m
United Airlines
Deal found 4/19![United Airlines logo]()
$409
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/125:45 am
PIT
- MCI
2 stops7h 15m
Southwest
Sun 6/148:30 am
MCI
- PIT
1 stop3h 35m
Southwest
Deal found 4/16![Southwest logo]()
$412
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:00 am
PIT
- MCI
1 stop6h 27m
Delta
Mon 10/125:26 pm
MCI
- PIT
1 stop5h 53m
Delta
Deal found 4/14![Delta logo]()
$407
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/229:25 am
PIT
- MCI
2 stops8h 45m
Southwest
Sun 5/2411:10 am
MCI
- PIT
1 stop9h 15m
Southwest
Deal found 4/16![Southwest logo]()
$422
This United Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/122:05 pm
PIT
- SGF
2 stops10h 37m
United Airlines
Tue 9/153:05 pm
SGF
- PIT
1 stop7h 44m
United Airlines
Deal found 4/19![United Airlines logo]()
$438
This Delta deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/116:00 am
PIT
- MCI
1 stop7h 27m
Delta
Wed 10/147:00 am
MCI
- PIT
1 stop7h 37m
Delta
Deal found 4/19![Delta logo]()
$407
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/202:05 pm
PIT
- JLN
1 stop5h 11m
United Airlines
Tue 6/238:54 am
JLN
- PIT
1 stop5h 29m
United Airlines
Deal found 4/17![United Airlines logo]()
$494
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/307:05 am
PIT
- JLN
1 stop7h 32m
United Airlines
Mon 5/49:06 am
JLN
- PIT
1 stop6h 45m
United Airlines
Deal found 4/15![United Airlines logo]()
$499
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:05 am
PIT
- JLN
1 stop7h 32m
United Airlines
Thu 5/211:57 pm
JLN
- PIT
1 stop7h 48m
United Airlines
Deal found 4/16![United Airlines logo]()
$581
Last-minute flights from Pittsburgh to MissouriDiscover last-minute flight deals from Pittsburgh to Missouri. Data last updated April 20, 2026 and is based on user searches.
Discover last-minute flight deals from Pittsburgh to Missouri. Data last updated April 20, 2026 and is based on user searches.
This Trip.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/19:59 am
PIT
- STL
1 stop14h 20m
Frontier
Sun 5/34:59 pm
STL
- PIT
1 stop15h 31m
Frontier
Deal found 4/15![Frontier logo]()
$253
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/78:15 pm
PIT
- MCI
1 stop14h 14m
Multiple Airlines
Wed 5/136:24 pm
MCI
- PIT
2 stops26h 43m
Multiple Airlines
Deal found 4/15![Multiple Airlines logo]()
$257
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/74:58 pm
PIT
- MCI
1 stop17h 31m
Spirit Airlines
Wed 5/1310:35 am
MCI
- PIT
1 stop28h 28m
Spirit Airlines
Deal found 4/15![Spirit Airlines logo]()
$307
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/123:09 pm
PIT
- STL
1 stop8h 10m
American Airlines
Wed 5/135:51 am
STL
- PIT
1 stop9h 57m
American Airlines
Deal found 4/17![American Airlines logo]()
$223
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/133:09 pm
PIT
- STL
1 stop9h 47m
American Airlines
Wed 5/206:54 pm
STL
- PIT
1 stop4h 29m
American Airlines
Deal found 4/15![American Airlines logo]()
$229
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:55 am
PIT
- STL
Nonstop1h 50m
Southwest
Thu 5/147:40 pm
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 4/16![Southwest logo]()
$241
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:50 pm
PIT
- STL
1 stop5h 09m
Delta
Mon 5/187:01 pm
STL
- PIT
1 stop4h 44m
Delta
Deal found 4/15![Delta logo]()
$255
This Southwest deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:55 am
PIT
- STL
2 stops8h 30m
Southwest
Tue 5/263:55 pm
STL
- PIT
1 stop6h 25m
Southwest
Deal found 4/18![Southwest logo]()
$240
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:50 pm
PIT
- STL
1 stop5h 09m
Delta
Mon 5/256:45 am
STL
- PIT
1 stop3h 28m
Delta
Deal found 4/16![Delta logo]()
$235
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:25 am
PIT
- STL
1 stop8h 55m
Southwest
Mon 5/257:40 pm
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 4/15![Southwest logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/229:29 pm
PIT
- MCI
1 stop13h 00m
Multiple Airlines
Wed 5/2710:35 am
MCI
- PIT
1 stop7h 45m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$295
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:15 am
PIT
- STL
Nonstop1h 50m
Southwest
Mon 5/2510:15 am
STL
- PIT
Nonstop1h 40m
Southwest
Deal found 4/17![Southwest logo]()
$217
One-way flights from Pittsburgh to MissouriSearch for one-way flight options from Pittsburgh to Missouri. Find affordable one-way fares based on user searches. Data last updated April 20, 2026.
Search for one-way flight options from Pittsburgh to Missouri. Find affordable one-way fares based on user searches. Data last updated April 20, 2026.
This Frontier deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/167:15 pm
PIT
- STL
1 stop6h 06m
Frontier
Deal found 4/16![Frontier logo]()
$70
This Trip.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/19:59 am
PIT
- STL
1 stop14h 20m
Frontier
Deal found 4/17![Frontier logo]()
$99
This Trip.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:15 pm
PIT
- STL
1 stop29h 06m
Frontier
Deal found 4/19![Frontier logo]()
$101
This Trip.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/159:44 am
PIT
- STL
1 stop15h 37m
Frontier
Deal found 4/16![Frontier logo]()
$105
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/188:15 pm
PIT
- STL
2 stops37h 40m
Frontier
Deal found 4/16![Frontier logo]()
$108
This Frontier deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/137:09 pm
PIT
- STL
1 stop6h 00m
Frontier
Deal found 4/15![Frontier logo]()
$109
This Priceline deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/157:09 pm
PIT
- STL
1 stop6h 00m
Frontier
Deal found 4/15![Frontier logo]()
$115
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/233:56 pm
PIT
- STL
1 stop9h 00m
American Airlines
Deal found 4/16![American Airlines logo]()
$117
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1711:50 am
PIT
- STL
1 stop5h 27m
Delta
Deal found 4/15![Delta logo]()
$118
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:16 pm
PIT
- STL
1 stop4h 10m
United Airlines
Deal found 4/15![United Airlines logo]()
$119
This Trip.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/78:15 pm
PIT
- STL
1 stop29h 06m
Frontier
Deal found 4/19![Frontier logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:15 pm
PIT
- MCI
1 stop14h 14m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$150
Find flight deals from Pittsburgh to Missouri
Keep the following information in mind while searching for Pittsburgh to Missouri flight deals. Data was last updated April 20, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $217 (Southwest) |
One-way from | $70 (Frontier) |
Popular in | October |
Cheapest in | November |
Average price | $384 |
Good round-trip deal | $378 or less |
Good one-way deal | $172 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Pittsburgh to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 20, 2026.
Use the filters below to find and compare flights from Pittsburgh to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Sat 5/23
7:15 am-8:05 am
Nonstop1h 50m
Lambert-St Louis
Mon 5/25
1:45 pm-9:20 pm
1 stop6h 35m
$226
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Sat 5/23
6:49 am-10:34 am
1 stop4h 45m
Lambert-St Louis
Wed 5/27
11:25 am-5:10 pm
1 stop4h 45m
$235
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Sat 5/9
6:37 pm-11:59 pm
1 stop6h 22m
Lambert-St Louis
Mon 5/11
6:04 pm-10:38 pm
1 stop3h 34m
$235
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Thu 5/21
6:25 am-2:20 pm
1 stop8h 55m
Lambert-St Louis
Mon 5/25
7:40 pm-10:15 pm
Nonstop1h 35m
$251
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Fri 5/22
7:50 pm-11:59 pm
1 stop5h 09m
Lambert-St Louis
Tue 5/26
6:45 am-11:13 am
1 stop3h 28m
$302
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Fri 6/12
7:59 pm-11:56 pm
1 stop4h 57m
Lambert-St Louis
Mon 6/15
5:24 pm-12:55 am
1 stop6h 31m
$302
Quickest round-trip
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Sun 5/24
11:45 am-4:35 pm
1 stop5h 50m
Lambert-St Louis
Tue 5/26
6:45 pm-9:20 pm
Nonstop1h 35m
$305
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Thu 5/14
7:50 pm-11:59 pm
1 stop5h 09m
Lambert-St Louis
Sat 5/16
7:05 pm-12:45 am
1 stop4h 40m
$307
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Thu 5/14
7:50 pm-11:59 pm
1 stop5h 09m
Lambert-St Louis
Mon 5/18
7:01 pm-12:45 am
1 stop4h 44m
$307
PittsburghSpringfield
PIT - SGF
PITSGF
Pittsburgh
Sat 9/12
7:00 am-11:01 am
1 stop5h 01m
Springfield-Branson
Tue 9/15
6:00 am-12:54 pm
1 stop5h 54m
$329
Showing 1-10 of 51 resultsSorted by cheapest first
Best time to book a flight from Pittsburgh to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Pittsburgh with our price prediction graph.
PIT-STL
PIT-JLN
PIT-MCI
PIT-SGF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Pittsburgh to Missouri
PIT-USMO
PIT-STL
PIT-JLN
PIT-MCI
PIT-SGF
What is the cheapest month to book a flight from Pittsburgh to Missouri?
Currently, November is the cheapest month in which you can book a flight from Pittsburgh to Missouri (average of $116). Flying from Pittsburgh to Missouri in March is currently the most expensive (average of $268). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PIT to MO?
Find hourly flight availability from Pittsburgh to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 20, 2026.
It’s optimal to fly from Pittsburgh to Missouri at noon. By choosing this option you can save up to 29% on the cost of your flight, compared to a flight in the morning.
How much does it cost to fly round-trip from Pittsburgh to Missouri?
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated April 20, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Pittsburgh to Missouri by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Pittsburgh to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Pittsburgh to Missouri
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Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Pittsburgh to Missouri by cabin class
Find flights from Pittsburgh to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Pittsburgh and Missouri flights
Browse other Pittsburgh and Missouri flight options. Last updated on April 20, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Pittsburgh to Missouri flights
Consider these flights traveling from Pittsburgh to Missouri.
Top 4 airlines flying from Pittsburgh to Missouri
Discover the top 4 airlines that operate flights from Pittsburgh to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 20, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$170 | Average$350 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$196 | Average$424 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$221 | Average$385 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$248 | Average$421 | FlexibilityNo cancel fee | On-timeN/A |