$99+ Cheap flights from Pittsburgh (PIT) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/28. Fares are subject to change and may not be available on all flights or dates of travel.
PIT — STL
Jun 6 — Jun 131
Round-trip
1 adult, Economy
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Cheapest flights from Pittsburgh to MissouriExplore the most affordable flight options available from Pittsburgh to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 7, 2026.
Explore the most affordable flight options available from Pittsburgh to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 7, 2026.
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/210:05 am
PIT
- STL
1 stop5h 21m
American Airlines
Tue 6/95:08 am
STL
- PIT
1 stop4h 08m
American Airlines
Deal found 5/6![American Airlines logo]()
$197
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:49 am
PIT
- STL
1 stop6h 22m
United Airlines
Sat 6/68:00 am
STL
- PIT
1 stop4h 07m
United Airlines
Deal found 5/6![United Airlines logo]()
$225
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/37:10 pm
PIT
- STL
Nonstop1h 50m
Southwest
Wed 6/1010:25 am
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 5/4![Southwest logo]()
$237
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/85:01 am
PIT
- STL
1 stop4h 31m
American Airlines
Tue 6/95:03 pm
STL
- PIT
1 stop5h 56m
American Airlines
Deal found 5/5![American Airlines logo]()
$250
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/88:15 pm
PIT
- STL
Nonstop1h 45m
Southwest
Tue 6/910:25 am
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 5/3![Southwest logo]()
$251
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:16 pm
PIT
- STL
1 stop4h 05m
United Airlines
Mon 6/87:22 am
STL
- PIT
1 stop4h 45m
United Airlines
Deal found 5/3![United Airlines logo]()
$252
This Mytrip deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/117:10 pm
PIT
- STL
1 stop5h 49m
Frontier
Thu 7/164:09 pm
STL
- PIT
1 stop25h 06m
Frontier
Deal found 5/6![Frontier logo]()
$253
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:50 am
PIT
- STL
Nonstop1h 50m
Southwest
Tue 6/210:15 am
STL
- PIT
Nonstop1h 40m
Southwest
Deal found 5/5![Southwest logo]()
$257
This Mytrip deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/68:15 pm
PIT
- STL
1 stop28h 42m
Frontier
Mon 6/811:38 am
STL
- PIT
1 stop6h 42m
Frontier
Deal found 5/6![Frontier logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1612:06 pm
PIT
- MCI
2 stops30h 15m
Multiple Airlines
Mon 7/2010:40 am
MCI
- PIT
1 stop11h 59m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$282
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/229:29 pm
PIT
- SGF
1 stop21h 17m
Allegiant Air
Sun 5/318:57 pm
SGF
- PIT
1 stop11h 24m
Allegiant Air
Deal found 5/4![Allegiant Air logo]()
$286
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/77:30 am
PIT
- MCI
1 stop10h 20m
Multiple Airlines
Mon 8/106:16 pm
MCI
- PIT
2 stops16h 52m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$296
Best flights from Pittsburgh to MissouriDiscover carefully curated flight deals from Pittsburgh to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 7, 2026.
Discover carefully curated flight deals from Pittsburgh to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 7, 2026.
This United Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/282:05 pm
PIT
- STL
1 stop4h 23m
United Airlines
Sat 5/305:29 pm
STL
- PIT
1 stop5h 30m
United Airlines
Deal found 5/2![United Airlines logo]()
$197
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/48:15 pm
PIT
- STL
Nonstop1h 45m
Southwest
Sat 6/64:00 pm
STL
- PIT
1 stop3h 10m
Southwest
Deal found 5/6![Southwest logo]()
$270
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/268:42 pm
PIT
- STL
1 stop4h 34m
American Airlines
Fri 7/39:24 am
STL
- PIT
1 stop4h 13m
American Airlines
Deal found 5/7![American Airlines logo]()
$303
This Delta deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/106:30 am
PIT
- STL
1 stop4h 01m
Delta
Sun 7/126:00 am
STL
- PIT
1 stop5h 52m
Delta
Deal found 5/2![Delta logo]()
$303
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:49 am
PIT
- STL
1 stop6h 22m
United Airlines
Sat 6/68:00 am
STL
- PIT
1 stop4h 07m
United Airlines
Deal found 5/6![United Airlines logo]()
$225
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/53:25 pm
PIT
- STL
1 stop6h 45m
Southwest
Fri 8/76:05 am
STL
- PIT
1 stop5h 05m
Southwest
Deal found 5/4![Southwest logo]()
$293
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:51 am
PIT
- STL
1 stop4h 20m
United Airlines
Wed 6/37:22 am
STL
- PIT
1 stop7h 01m
United Airlines
Deal found 5/6![United Airlines logo]()
$277
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/15:40 am
PIT
- MCI
1 stop4h 49m
Delta
Sat 6/61:36 pm
MCI
- PIT
1 stop7h 01m
Delta
Deal found 5/3![Delta logo]()
$321
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/58:15 pm
PIT
- STL
Nonstop1h 45m
Southwest
Sun 6/77:55 pm
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 5/5![Southwest logo]()
$303
This Delta deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:07 pm
PIT
- MCI
1 stop3h 45m
Delta
Sat 5/308:05 am
MCI
- PIT
1 stop6h 29m
Delta
Deal found 5/2![Delta logo]()
$321
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/176:45 am
PIT
- STL
Nonstop1h 45m
Southwest
Sun 7/197:55 pm
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 5/4![Southwest logo]()
$303
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/310:54 am
PIT
- MCI
1 stop4h 26m
United Airlines
Wed 6/105:10 pm
MCI
- PIT
1 stop5h 49m
United Airlines
Deal found 5/6![United Airlines logo]()
$317
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:52 am
PIT
- SGF
1 stop5h 35m
Delta
Fri 5/296:49 pm
SGF
- PIT
1 stop4h 56m
Delta
Deal found 5/3![Delta logo]()
$324
This Southwest deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:50 am
PIT
- STL
Nonstop1h 40m
Southwest
Mon 9/2811:40 am
STL
- PIT
1 stop5h 00m
Southwest
Deal found 5/2![Southwest logo]()
$303
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/107:00 am
PIT
- SGF
1 stop4h 55m
Delta
Tue 7/146:53 pm
SGF
- PIT
1 stop4h 49m
Delta
Deal found 5/4![Delta logo]()
$324
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/191:40 pm
PIT
- SGF
1 stop5h 26m
Delta
Tue 6/26:49 pm
SGF
- PIT
1 stop4h 56m
Delta
Deal found 5/3![Delta logo]()
$324
This United Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/236:16 pm
PIT
- MCI
1 stop5h 57m
United Airlines
Sat 6/277:53 am
MCI
- PIT
1 stop4h 16m
United Airlines
Deal found 5/4![United Airlines logo]()
$357
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:25 am
PIT
- MCI
2 stops9h 10m
Southwest
Wed 6/101:00 pm
MCI
- PIT
1 stop8h 10m
Southwest
Deal found 5/6![Southwest logo]()
$328
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:52 am
PIT
- SGF
1 stop5h 35m
Delta
Wed 5/276:49 pm
SGF
- PIT
1 stop4h 56m
Delta
Deal found 5/3![Delta logo]()
$324
This United Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/410:54 am
PIT
- MCI
1 stop6h 06m
United Airlines
Sun 6/77:53 am
MCI
- PIT
1 stop4h 14m
United Airlines
Deal found 5/2![United Airlines logo]()
$364
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:52 am
PIT
- SGF
1 stop5h 35m
Delta
Tue 6/26:49 pm
SGF
- PIT
1 stop4h 56m
Delta
Deal found 5/3![Delta logo]()
$324
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:00 am
PIT
- SGF
1 stop4h 43m
United Airlines
Wed 9/26:35 pm
SGF
- PIT
1 stop4h 40m
United Airlines
Deal found 5/6![United Airlines logo]()
$389
This Delta deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:05 pm
PIT
- MCI
1 stop6h 53m
Delta
Mon 10/125:26 pm
MCI
- PIT
1 stop5h 53m
Delta
Deal found 5/6![Delta logo]()
$331
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/218:36 am
PIT
- JLN
1 stop5h 46m
United Airlines
Mon 5/258:54 am
JLN
- PIT
1 stop7h 16m
United Airlines
Deal found 5/6![United Airlines logo]()
$406
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/116:00 am
PIT
- MCI
1 stop7h 27m
Delta
Wed 10/1410:35 am
MCI
- PIT
1 stop5h 30m
Delta
Deal found 5/5![Delta logo]()
$362
This United Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2310:30 am
PIT
- MCI
2 stops12h 17m
United Airlines
Sat 5/306:45 pm
MCI
- PIT
1 stop4h 14m
United Airlines
Deal found 5/2![United Airlines logo]()
$406
This Delta deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:05 pm
PIT
- MCI
1 stop5h 17m
Delta
Mon 10/55:26 pm
MCI
- PIT
1 stop5h 56m
Delta
Deal found 5/6![Delta logo]()
$364
This United Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/110:54 am
PIT
- MCI
1 stop6h 05m
United Airlines
Sat 6/66:00 am
MCI
- PIT
2 stops7h 05m
United Airlines
Deal found 5/2![United Airlines logo]()
$406
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:10 am
PIT
- SGF
2 stops9h 25m
United Airlines
Sat 5/306:35 pm
SGF
- PIT
1 stop4h 24m
United Airlines
Deal found 5/3![United Airlines logo]()
$409
This United Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/121:05 pm
PIT
- SGF
1 stop6h 36m
United Airlines
Tue 9/156:00 am
SGF
- PIT
2 stops7h 01m
United Airlines
Deal found 5/2![United Airlines logo]()
$462
Last-minute flights from Pittsburgh to MissouriDiscover last-minute flight deals from Pittsburgh to Missouri. Data last updated May 7, 2026 and is based on user searches.
Discover last-minute flight deals from Pittsburgh to Missouri. Data last updated May 7, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/179:00 am
PIT
- SGF
1 stop25h 26m
Allegiant Air
Sun 5/318:57 pm
SGF
- PIT
1 stop11h 24m
Allegiant Air
Deal found 5/3![Allegiant Air logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/229:29 pm
PIT
- SGF
1 stop21h 17m
Allegiant Air
Sun 5/318:57 pm
SGF
- PIT
1 stop11h 24m
Allegiant Air
Deal found 5/4![Allegiant Air logo]()
$286
This American Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/306:37 am
PIT
- STL
1 stop6h 22m
American Airlines
Tue 6/26:35 am
STL
- PIT
1 stop5h 07m
American Airlines
Deal found 5/2![American Airlines logo]()
$263
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/210:05 am
PIT
- STL
1 stop5h 21m
American Airlines
Tue 6/95:08 am
STL
- PIT
1 stop4h 08m
American Airlines
Deal found 5/6![American Airlines logo]()
$197
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:50 am
PIT
- STL
Nonstop1h 50m
Southwest
Tue 6/210:15 am
STL
- PIT
Nonstop1h 40m
Southwest
Deal found 5/5![Southwest logo]()
$257
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/210:54 am
PIT
- MCI
1 stop4h 26m
United Airlines
Tue 6/96:00 am
MCI
- PIT
1 stop6h 07m
United Airlines
Deal found 5/3![United Airlines logo]()
$307
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/37:10 pm
PIT
- STL
Nonstop1h 50m
Southwest
Wed 6/1010:25 am
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 5/4![Southwest logo]()
$237
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:49 am
PIT
- STL
1 stop6h 22m
United Airlines
Sat 6/68:00 am
STL
- PIT
1 stop4h 07m
United Airlines
Deal found 5/6![United Airlines logo]()
$225
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:16 pm
PIT
- STL
1 stop4h 05m
United Airlines
Mon 6/87:22 am
STL
- PIT
1 stop4h 45m
United Airlines
Deal found 5/3![United Airlines logo]()
$252
This Mytrip deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/68:15 pm
PIT
- STL
1 stop28h 42m
Frontier
Mon 6/811:38 am
STL
- PIT
1 stop6h 42m
Frontier
Deal found 5/6![Frontier logo]()
$260
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/85:01 am
PIT
- STL
1 stop4h 31m
American Airlines
Tue 6/95:03 pm
STL
- PIT
1 stop5h 56m
American Airlines
Deal found 5/5![American Airlines logo]()
$250
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/88:15 pm
PIT
- STL
Nonstop1h 45m
Southwest
Tue 6/910:25 am
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 5/3![Southwest logo]()
$251
One-way flights from Pittsburgh to MissouriSearch for one-way flight options from Pittsburgh to Missouri. Find affordable one-way fares based on user searches. Data last updated May 7, 2026.
Search for one-way flight options from Pittsburgh to Missouri. Find affordable one-way fares based on user searches. Data last updated May 7, 2026.
This American Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:00 am
PIT
- STL
1 stop4h 33m
American Airlines
Deal found 5/3![American Airlines logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:15 pm
PIT
- STL
1 stop28h 42m
Frontier
Deal found 5/4![Frontier logo]()
$101
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:00 am
PIT
- STL
2 stops36h 33m
Multiple Airlines
Deal found 5/6![Multiple Airlines logo]()
$102
This Frontier deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/17:10 pm
PIT
- STL
1 stop5h 49m
Frontier
Deal found 5/6![Frontier logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/412:04 pm
PIT
- STL
2 stops21h 51m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:15 pm
PIT
- STL
1 stop28h 42m
Frontier
Deal found 5/4![Frontier logo]()
$112
This Frontier deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/317:10 pm
PIT
- STL
1 stop5h 49m
Frontier
Deal found 5/6![Frontier logo]()
$115
This Frontier deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/177:10 pm
PIT
- STL
1 stop5h 49m
Frontier
Deal found 5/4![Frontier logo]()
$116
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/247:45 pm
PIT
- STL
Nonstop1h 45m
Southwest
Deal found 5/3![Southwest logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:00 am
PIT
- STL
2 stops27h 52m
Multiple Airlines
Deal found 5/6![Multiple Airlines logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/296:00 am
PIT
- STL
2 stops36h 30m
Multiple Airlines
Deal found 5/7![Multiple Airlines logo]()
$124
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/234:55 pm
PIT
- STL
1 stop6h 23m
Delta
Deal found 5/4![Delta logo]()
$129
Find flight deals from Pittsburgh to Missouri
Keep the following information in mind while searching for Pittsburgh to Missouri flight deals. Data was last updated May 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $197 (American Airlines) |
One-way from | $99 (American Airlines) |
Popular in | April |
Cheapest in | November |
Average price | $349 |
Good round-trip deal | $378 or less |
Good one-way deal | $178 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Pittsburgh to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 7, 2026.
Use the filters below to find and compare flights from Pittsburgh to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Thu 5/28
2:05 pm-5:28 pm
1 stop4h 23m
Lambert-St Louis
Sat 5/30
5:29 pm-11:59 pm
1 stop5h 30m
$197
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Thu 6/4
6:49 am-12:11 pm
1 stop6h 22m
Lambert-St Louis
Sat 6/6
8:00 am-1:07 pm
1 stop4h 07m
$225
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Thu 6/4
8:15 pm-9:00 pm
Nonstop1h 45m
Lambert-St Louis
Sat 6/6
4:00 pm-8:10 pm
1 stop3h 10m
$270
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Tue 6/2
8:51 am-12:11 pm
1 stop4h 20m
Lambert-St Louis
Wed 6/3
7:22 am-3:23 pm
1 stop7h 01m
$277
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Wed 8/5
3:25 pm-9:10 pm
1 stop6h 45m
Lambert-St Louis
Fri 8/7
6:05 am-12:10 pm
1 stop5h 05m
$293
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Fri 6/26
8:42 pm-12:16 am
1 stop4h 34m
Lambert-St Louis
Fri 7/3
9:24 am-2:37 pm
1 stop4h 13m
$303
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Fri 7/10
6:30 am-9:31 am
1 stop4h 01m
Lambert-St Louis
Sun 7/12
6:00 am-12:52 pm
1 stop5h 52m
$303
Quickest round-trip
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Fri 6/5
8:15 pm-9:00 pm
Nonstop1h 45m
Lambert-St Louis
Sun 6/7
7:55 pm-10:30 pm
Nonstop1h 35m
$303
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Fri 7/17
6:45 am-7:30 am
Nonstop1h 45m
Lambert-St Louis
Sun 7/19
7:55 pm-10:30 pm
Nonstop1h 35m
$303
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Sat 9/26
6:50 am-7:30 am
Nonstop1h 40m
Lambert-St Louis
Mon 9/28
11:40 am-5:40 pm
1 stop5h 00m
$303
Showing 1-10 of 55 resultsSorted by cheapest first
Best time to book a flight from Pittsburgh to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Pittsburgh with our price prediction graph.
PIT-STL
PIT-MCI
PIT-SGF
PIT-JLN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Pittsburgh to Missouri
PIT-USMO
PIT-STL
PIT-MCI
PIT-SGF
PIT-JLN
How far ahead should I book a flight from Pittsburgh to Missouri?
The best time to book flights from Pittsburgh to Missouri is 28 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Pittsburgh to Missouri?
Currently, November is the cheapest month in which you can book a flight from Pittsburgh to Missouri (average of $116). Flying from Pittsburgh to Missouri in March is currently the most expensive (average of $268). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PIT to MO?
Find hourly flight availability from Pittsburgh to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 7, 2026.
It’s optimal to fly from Pittsburgh to Missouri at noon. By choosing this option you can save up to 30% on the cost of your flight, compared to a flight in the morning.
How much does it cost to fly round-trip from Pittsburgh to Missouri?
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated May 7, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Pittsburgh to Missouri by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.6
Overall
7.9
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Crew
8.6
Overall
7.9
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Crew
8.6
Overall
7.9
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Crew
8.6
Overall
7.9
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Crew
8.6
Overall
7.9
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Pittsburgh to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Pittsburgh to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Pittsburgh to Missouri by cabin class
Find flights from Pittsburgh to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Pittsburgh and Missouri flights
Browse other Pittsburgh and Missouri flight options. Last updated on May 7, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Pittsburgh to Missouri flights
Consider these flights traveling from Pittsburgh to Missouri.
Top 4 airlines flying from Pittsburgh to Missouri
Discover the top 4 airlines that operate flights from Pittsburgh to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$170 | Average$357 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$221 | Average$396 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$248 | Average$404 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$277 | Average$421 | FlexibilityNo cancel fee | On-time69% |