$80+ Cheap flights from Pittsburgh (PIT) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/27. Fares are subject to change and may not be available on all flights or dates of travel.
PIT — STL
Apr 3 — Apr 101
1 adult, Economy
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Find cheap flights from Pittsburgh to Missouri with Cheapflights
1. Tell us where you want to go
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Cheapest flights from Pittsburgh to MissouriExplore the most affordable flight options available from Pittsburgh to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 4, 2026.
Explore the most affordable flight options available from Pittsburgh to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 4, 2026.
This Delta deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/291:50 pm
PIT
- STL
1 stop5h 12m
Delta
Tue 9/16:45 am
STL
- PIT
1 stop3h 26m
Delta
Deal found 3/2![Delta logo]()
$245
This United Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/297:00 am
PIT
- JLN
1 stop7h 12m
United Airlines
Wed 5/62:28 pm
JLN
- PIT
1 stop8h 21m
United Airlines
Deal found 2/28![United Airlines logo]()
$264
This Delta deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:00 am
PIT
- STL
1 stop5h 34m
Delta
Sat 4/185:59 pm
STL
- PIT
1 stop3h 57m
Delta
Deal found 3/2![Delta logo]()
$267
This Southwest deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/244:20 pm
PIT
- STL
1 stop8h 20m
Southwest
Tue 4/286:45 pm
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 3/3![Southwest logo]()
$268
This Delta deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:25 pm
PIT
- SGF
1 stop4h 54m
Delta
Tue 5/266:52 pm
SGF
- PIT
1 stop4h 53m
Delta
Deal found 3/2![Delta logo]()
$269
This Southwest deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/295:55 pm
PIT
- STL
1 stop6h 10m
Southwest
Sun 4/55:20 am
STL
- PIT
1 stop3h 40m
Southwest
Deal found 2/28![Southwest logo]()
$271
This Southwest deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:05 am
PIT
- STL
2 stops7h 55m
Southwest
Sat 4/188:45 am
STL
- PIT
1 stop7h 20m
Southwest
Deal found 3/2![Southwest logo]()
$272
This United Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/232:05 pm
PIT
- JLN
1 stop5h 11m
United Airlines
Mon 5/251:57 pm
JLN
- PIT
1 stop7h 48m
United Airlines
Deal found 3/2![United Airlines logo]()
$274
This United Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/184:14 pm
PIT
- SGF
2 stops8h 28m
United Airlines
Mon 8/246:35 pm
SGF
- PIT
1 stop4h 40m
United Airlines
Deal found 2/28![United Airlines logo]()
$274
This Southwest deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/262:25 pm
PIT
- STL
1 stop5h 30m
Southwest
Sat 3/285:00 am
STL
- PIT
1 stop6h 05m
Southwest
Deal found 3/3![Southwest logo]()
$275
This Southwest deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/94:20 pm
PIT
- STL
1 stop8h 20m
Southwest
Tue 4/146:45 pm
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 3/4![Southwest logo]()
$278
This American Airlines deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/155:02 am
PIT
- SGF
1 stop6h 07m
American Airlines
Sat 3/216:00 pm
SGF
- PIT
1 stop5h 11m
American Airlines
Deal found 3/1![American Airlines logo]()
$279
Best flights from Pittsburgh to MissouriDiscover carefully curated flight deals from Pittsburgh to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 4, 2026.
Discover carefully curated flight deals from Pittsburgh to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 4, 2026.
This Delta deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2911:45 am
PIT
- STL
1 stop5h 12m
Delta
Mon 8/317:05 pm
STL
- PIT
1 stop4h 17m
Delta
Deal found 3/1![Delta logo]()
$267
This Southwest deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/198:45 pm
PIT
- STL
1 stop4h 20m
Southwest
Mon 3/234:45 pm
STL
- PIT
1 stop3h 40m
Southwest
Deal found 3/2![Southwest logo]()
$275
This American Airlines deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/155:02 am
PIT
- SGF
1 stop6h 07m
American Airlines
Sat 3/216:00 pm
SGF
- PIT
1 stop5h 11m
American Airlines
Deal found 3/1![American Airlines logo]()
$279
This United Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:11 pm
PIT
- STL
1 stop4h 05m
United Airlines
Sun 7/199:23 am
STL
- PIT
1 stop6h 42m
United Airlines
Deal found 2/27![United Airlines logo]()
$287
This Delta deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:00 am
PIT
- STL
1 stop6h 09m
Delta
Thu 4/96:59 pm
STL
- PIT
1 stop4h 18m
Delta
Deal found 2/27![Delta logo]()
$267
This Southwest deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/94:20 pm
PIT
- STL
1 stop8h 20m
Southwest
Tue 4/146:45 pm
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 3/4![Southwest logo]()
$278
This Delta deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/32:07 pm
PIT
- STL
1 stop3h 25m
Delta
Sun 4/56:32 am
STL
- PIT
1 stop5h 55m
Delta
Deal found 2/28![Delta logo]()
$267
This United Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:00 pm
PIT
- MCI
1 stop4h 59m
United Airlines
Wed 4/221:54 pm
MCI
- PIT
1 stop7h 56m
United Airlines
Deal found 3/3![United Airlines logo]()
$294
This Southwest deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/78:45 am
PIT
- STL
1 stop6h 45m
Southwest
Thu 4/97:40 pm
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 2/27![Southwest logo]()
$283
This Delta deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2110:31 am
PIT
- STL
1 stop3h 39m
Delta
Mon 5/257:01 pm
STL
- PIT
1 stop4h 44m
Delta
Deal found 2/27![Delta logo]()
$267
This Delta deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1411:45 am
PIT
- STL
1 stop5h 13m
Delta
Tue 7/2111:51 am
STL
- PIT
1 stop4h 18m
Delta
Deal found 2/28![Delta logo]()
$267
This United Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:00 am
PIT
- JLN
1 stop7h 37m
United Airlines
Sat 5/29:06 am
JLN
- PIT
1 stop5h 15m
United Airlines
Deal found 2/27![United Airlines logo]()
$334
This Delta deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:25 pm
PIT
- SGF
1 stop4h 42m
Delta
Mon 4/206:55 pm
SGF
- PIT
1 stop4h 40m
Delta
Deal found 2/27![Delta logo]()
$269
This United Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/232:05 pm
PIT
- JLN
1 stop5h 11m
United Airlines
Wed 5/278:54 am
JLN
- PIT
1 stop5h 29m
United Airlines
Deal found 3/4![United Airlines logo]()
$337
This Delta deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/184:25 pm
PIT
- SGF
1 stop7h 04m
Delta
Mon 8/246:45 pm
SGF
- PIT
1 stop4h 37m
Delta
Deal found 2/28![Delta logo]()
$269
This United Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/134:50 pm
PIT
- MCI
1 stop6h 39m
United Airlines
Fri 5/156:56 pm
MCI
- PIT
1 stop4h 03m
United Airlines
Deal found 3/2![United Airlines logo]()
$337
This Delta deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/201:40 pm
PIT
- SGF
1 stop5h 26m
Delta
Wed 5/276:52 pm
SGF
- PIT
1 stop4h 53m
Delta
Deal found 3/2![Delta logo]()
$269
This United Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/36:00 am
PIT
- MCI
1 stop7h 08m
United Airlines
Wed 5/62:59 pm
MCI
- PIT
1 stop7h 45m
United Airlines
Deal found 2/27![United Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/46:00 am
PIT
- SGF
1 stop6h 07m
Delta
Wed 4/86:00 am
SGF
- PIT
1 stop5h 37m
Delta
Deal found 2/27![Delta logo]()
$269
This United Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/84:17 pm
PIT
- MCI
1 stop8h 34m
United Airlines
Mon 5/114:15 pm
MCI
- PIT
1 stop6h 29m
United Airlines
Deal found 2/28![United Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/194:45 pm
PIT
- SGF
1 stop6h 34m
Delta
Fri 5/296:52 pm
SGF
- PIT
1 stop4h 53m
Delta
Deal found 3/2![Delta logo]()
$269
This United Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:00 am
PIT
- MCI
1 stop9h 01m
United Airlines
Wed 5/61:05 pm
MCI
- PIT
2 stops9h 18m
United Airlines
Deal found 3/2![United Airlines logo]()
$362
This Delta deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1411:45 am
PIT
- STL
1 stop5h 12m
Delta
Tue 8/181:30 pm
STL
- PIT
1 stop5h 43m
Delta
Deal found 3/2![Delta logo]()
$287
This United Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/144:25 pm
PIT
- JLN
1 stop8h 03m
United Airlines
Wed 3/188:54 am
JLN
- PIT
1 stop6h 56m
United Airlines
Deal found 2/27![United Airlines logo]()
$374
This Delta deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2710:31 am
PIT
- STL
1 stop3h 39m
Delta
Sun 5/316:00 am
STL
- PIT
1 stop5h 45m
Delta
Deal found 3/2![Delta logo]()
$287
This United Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/73:00 pm
PIT
- MCI
2 stops8h 30m
United Airlines
Wed 4/88:00 am
MCI
- PIT
1 stop4h 05m
United Airlines
Deal found 2/27![United Airlines logo]()
$376
This Delta deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1910:07 am
PIT
- MCI
1 stop7h 01m
Delta
Wed 5/207:05 am
MCI
- PIT
1 stop7h 29m
Delta
Deal found 2/28![Delta logo]()
$301
This United Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:10 am
PIT
- MCI
2 stops9h 16m
United Airlines
Wed 5/206:56 pm
MCI
- PIT
1 stop4h 03m
United Airlines
Deal found 3/2![United Airlines logo]()
$376
This Delta deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/146:00 am
PIT
- SGF
1 stop6h 08m
Delta
Tue 3/176:55 pm
SGF
- PIT
1 stop4h 22m
Delta
Deal found 2/28![Delta logo]()
$309
This United Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/277:20 pm
PIT
- JLN
1 stop19h 17m
United Airlines
Sun 5/32:28 pm
JLN
- PIT
1 stop8h 21m
United Airlines
Deal found 3/2![United Airlines logo]()
$401
Last-minute flights from Pittsburgh to MissouriDiscover last-minute flight deals from Pittsburgh to Missouri. Data last updated March 4, 2026 and is based on user searches.
Discover last-minute flight deals from Pittsburgh to Missouri. Data last updated March 4, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/155:02 am
PIT
- SGF
1 stop6h 07m
American Airlines
Sat 3/216:00 pm
SGF
- PIT
1 stop5h 11m
American Airlines
Deal found 3/1![American Airlines logo]()
$279
This Southwest deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/165:55 pm
PIT
- STL
1 stop6h 10m
Southwest
Mon 3/304:25 pm
STL
- PIT
2 stops6h 15m
Southwest
Deal found 3/1![Southwest logo]()
$280
This Southwest deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/262:25 pm
PIT
- STL
1 stop5h 30m
Southwest
Sat 3/285:00 am
STL
- PIT
1 stop6h 05m
Southwest
Deal found 3/3![Southwest logo]()
$275
This Southwest deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/295:55 pm
PIT
- STL
1 stop6h 10m
Southwest
Sun 4/55:20 am
STL
- PIT
1 stop3h 40m
Southwest
Deal found 2/28![Southwest logo]()
$271
This Delta deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/46:00 am
PIT
- SGF
1 stop6h 07m
Delta
Wed 4/86:00 am
SGF
- PIT
1 stop5h 37m
Delta
Deal found 2/27![Delta logo]()
$269
This Southwest deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/94:20 pm
PIT
- STL
1 stop8h 20m
Southwest
Tue 4/146:45 pm
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 3/4![Southwest logo]()
$278
This Southwest deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:55 am
PIT
- STL
Nonstop1h 50m
Southwest
Thu 4/161:45 pm
STL
- PIT
1 stop6h 35m
Southwest
Deal found 3/2![Southwest logo]()
$283
This Southwest deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:05 am
PIT
- STL
2 stops7h 55m
Southwest
Sat 4/188:45 am
STL
- PIT
1 stop7h 20m
Southwest
Deal found 3/2![Southwest logo]()
$272
This American Airlines deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:54 am
PIT
- STL
1 stop5h 15m
American Airlines
Sat 4/186:53 pm
STL
- PIT
1 stop4h 30m
American Airlines
Deal found 3/1![American Airlines logo]()
$245
This Delta deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:00 am
PIT
- STL
1 stop5h 34m
Delta
Sat 4/185:59 pm
STL
- PIT
1 stop3h 57m
Delta
Deal found 3/2![Delta logo]()
$267
This Southwest deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/244:20 pm
PIT
- STL
1 stop8h 20m
Southwest
Tue 4/286:45 pm
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 3/3![Southwest logo]()
$268
This United Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/297:00 am
PIT
- JLN
1 stop7h 12m
United Airlines
Wed 5/62:28 pm
JLN
- PIT
1 stop8h 21m
United Airlines
Deal found 2/28![United Airlines logo]()
$264
One-way flights from Pittsburgh to MissouriSearch for one-way flight options from Pittsburgh to Missouri. Find affordable one-way fares based on user searches. Data last updated March 4, 2026.
Search for one-way flight options from Pittsburgh to Missouri. Find affordable one-way fares based on user searches. Data last updated March 4, 2026.
This Priceline deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/273:00 pm
PIT
- STL
1 stop9h 19m
Frontier
Deal found 2/27![Frontier logo]()
$80
This Frontier deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/54:30 pm
PIT
- STL
1 stop8h 27m
Frontier
Deal found 3/3![Frontier logo]()
$101
This Frontier deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/212:44 pm
PIT
- STL
1 stop11h 35m
Frontier
Deal found 3/3![Frontier logo]()
$107
This Gotogate deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/176:00 am
PIT
- MCI
1 stop6h 29m
Spirit Airlines
Deal found 3/1![Spirit Airlines logo]()
$110
This Delta deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:00 am
PIT
- STL
1 stop6h 53m
Delta
Deal found 3/1![Delta logo]()
$112
This Expedia deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/37:40 pm
PIT
- STL
1 stop13h 11m
Frontier
Deal found 3/3![Frontier logo]()
$121
This Southwest deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/201:35 pm
PIT
- STL
1 stop6h 20m
Southwest
Deal found 3/3![Southwest logo]()
$134
This Priceline deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/34:30 pm
PIT
- STL
1 stop8h 27m
Frontier
Deal found 3/3![Frontier logo]()
$135
This Delta deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/257:35 pm
PIT
- STL
1 stop5h 23m
Delta
Deal found 2/27![Delta logo]()
$138
This Southwest deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:05 am
PIT
- STL
2 stops7h 55m
Southwest
Deal found 2/28![Southwest logo]()
$139
This Southwest deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:35 am
PIT
- STL
2 stops9h 15m
Southwest
Deal found 2/27![Southwest logo]()
$143
This Delta deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:30 am
PIT
- STL
1 stop5h 14m
Delta
Deal found 3/2![Delta logo]()
$144
Find flight deals from Pittsburgh to Missouri
Keep the following information in mind while searching for Pittsburgh to Missouri flight deals. Data was last updated March 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $245 (Delta) |
One-way from | $80 (Priceline) |
Popular in | October |
Cheapest in | November |
Average price | $387 |
Good round-trip deal | $337 or less |
Good one-way deal | $171 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Pittsburgh to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 4, 2026.
Use the filters below to find and compare flights from Pittsburgh to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Sat 8/29
11:45 am-3:57 pm
1 stop5h 12m
Lambert-St Louis
Mon 8/31
7:05 pm-12:22 am
1 stop4h 17m
$267
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Tue 4/7
6:00 am-11:09 am
1 stop6h 09m
Lambert-St Louis
Thu 4/9
6:59 pm-12:17 am
1 stop4h 18m
$267
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Fri 4/3
2:07 pm-4:32 pm
1 stop3h 25m
Lambert-St Louis
Sun 4/5
6:32 am-1:27 pm
1 stop5h 55m
$267
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Thu 5/21
10:31 am-1:10 pm
1 stop3h 39m
Lambert-St Louis
Mon 5/25
7:01 pm-12:45 am
1 stop4h 44m
$267
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Tue 7/14
11:45 am-3:58 pm
1 stop5h 13m
Lambert-St Louis
Tue 7/21
11:51 am-5:09 pm
1 stop4h 18m
$267
PittsburghSpringfield
PIT - SGF
PITSGF
Pittsburgh
Mon 4/13
5:25 pm-9:07 pm
1 stop4h 42m
Springfield-Branson
Mon 4/20
6:55 pm-12:35 am
1 stop4h 40m
$269
PittsburghSpringfield
PIT - SGF
PITSGF
Pittsburgh
Tue 8/18
4:25 pm-10:29 pm
1 stop7h 04m
Springfield-Branson
Mon 8/24
6:45 pm-12:22 am
1 stop4h 37m
$269
PittsburghSpringfield
PIT - SGF
PITSGF
Pittsburgh
Wed 5/20
1:40 pm-6:06 pm
1 stop5h 26m
Springfield-Branson
Wed 5/27
6:52 pm-12:45 am
1 stop4h 53m
$269
PittsburghSpringfield
PIT - SGF
PITSGF
Pittsburgh
Sat 4/4
6:00 am-11:07 am
1 stop6h 07m
Springfield-Branson
Wed 4/8
6:00 am-12:37 pm
1 stop5h 37m
$269
PittsburghSpringfield
PIT - SGF
PITSGF
Pittsburgh
Tue 5/19
4:45 pm-10:19 pm
1 stop6h 34m
Springfield-Branson
Fri 5/29
6:52 pm-12:45 am
1 stop4h 53m
$269
Showing 1-10 of 50 resultsSorted by cheapest first
Best time to book a flight from Pittsburgh to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Pittsburgh with our price prediction graph.
PIT-STL
PIT-JLN
PIT-SGF
PIT-MCI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Pittsburgh to Missouri
PIT-USMO
PIT-STL
PIT-JLN
PIT-SGF
PIT-MCI
What is the cheapest month to book a flight from Pittsburgh to Missouri?
Currently, November is the cheapest month in which you can book a flight from Pittsburgh to Missouri (average of $156). Flying from Pittsburgh to Missouri in July is currently the most expensive (average of $267). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PIT to MO?
Find hourly flight availability from Pittsburgh to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 4, 2026.
It’s optimal to fly from Pittsburgh to Missouri at noon. By choosing this option you can save up to 27% on the cost of your flight, compared to a flight in the morning.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated March 4, 2026.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Pittsburgh to Missouri by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Related info for your journey
Find useful and relevant information for your journey from Pittsburgh to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Pittsburgh to Missouri
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Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Pittsburgh to Missouri by cabin class
Find flights from Pittsburgh to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Pittsburgh and Missouri flights
Browse other Pittsburgh and Missouri flight options. Last updated on March 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Pittsburgh to Missouri flights
Consider these flights traveling from Pittsburgh to Missouri.
Top 4 airlines flying from Pittsburgh to Missouri
Discover the top 4 airlines that operate flights from Pittsburgh to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$170 | Average$349 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$241 | Average$374 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$248 | Average$438 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$277 | Average$420 | FlexibilityNo cancel fee | On-time69% |