$90+ Cheap flights from Pittsburgh (PIT) to Missouri
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/21. Fares are subject to change and may not be available on all flights or dates of travel.
PIT — STL
Nov 21 — Nov 281
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Pittsburgh to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Pittsburgh to Missouri
Cheapest
Best
Last-minute
One-way
Cheapest flights from Pittsburgh to MissouriExplore the most affordable flight options available from Pittsburgh to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 22, 2026.
Explore the most affordable flight options available from Pittsburgh to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 22, 2026.
This Frontier deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:27 pm -
1 stop18h 58m
Mon 11/236:05 pm -
1 stop22h 59m
Deal found 10/19![Frontier logo]()
$174
This Trip.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:28 pm -
1 stop6h 44m
Tue 12/295:58 pm -
1 stop22h 26m
Deal found 10/21![Frontier logo]()
$206
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:45 am -
Nonstop1h 55m
Tue 12/16:15 pm -
Nonstop1h 40m
Deal found 10/20![Southwest logo]()
$212
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:30 pm -
Nonstop1h 55m
Wed 11/253:55 pm -
1 stop6h 55m
Deal found 10/19![Southwest logo]()
$216
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/121:10 pm -
Nonstop1h 50m
Tue 12/297:55 pm -
Nonstop1h 40m
Deal found 10/21![Southwest logo]()
$218
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/114:03 pm -
1 stop4h 19m
Wed 11/181:20 pm -
1 stop6h 37m
Deal found 10/19![American Airlines logo]()
$219
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:50 am -
Nonstop1h 55m
Sat 11/219:50 am -
Nonstop1h 35m
Deal found 10/20![Southwest logo]()
$224
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/35:47 am -
1 stop5h 21m
Sun 12/67:27 am -
1 stop6h 43m
Deal found 10/21![American Airlines logo]()
$226
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:50 am -
Nonstop1h 55m
Wed 11/1812:40 pm -
1 stop4h 15m
Deal found 10/19![Southwest logo]()
$232
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/123:14 pm -
1 stop7h 28m
Fri 11/136:00 pm -
1 stop3h 49m
Deal found 10/21![Delta logo]()
$233
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:50 am -
1 stop6h 10m
Thu 11/123:35 pm -
1 stop7h 10m
Deal found 10/19![Southwest logo]()
$267
This Southwest deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/164:25 pm -
1 stop6h 45m
Mon 11/232:35 pm -
1 stop5h 45m
Deal found 10/18![Southwest logo]()
$288
Best flights from Pittsburgh to MissouriDiscover carefully curated flight deals from Pittsburgh to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 22, 2026.
Discover carefully curated flight deals from Pittsburgh to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 22, 2026.
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:30 pm -
Nonstop1h 55m
Wed 11/253:55 pm -
1 stop6h 55m
Deal found 10/19![Southwest logo]()
$216
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:10 am -
1 stop4h 15m
Tue 12/15:51 pm -
1 stop5h 55m
Deal found 10/20![Delta logo]()
$219
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/912:58 pm -
1 stop6h 01m
Wed 12/306:44 pm -
1 stop4h 38m
Deal found 10/19![American Airlines logo]()
$328
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/156:00 am -
1 stop6h 46m
Tue 12/155:00 pm -
1 stop5h 59m
Deal found 10/16![United Airlines logo]()
$364
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:10 am -
1 stop9h 00m
Tue 12/297:55 pm -
Nonstop1h 40m
Deal found 10/21![Southwest logo]()
$222
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/311:02 am -
1 stop6h 22m
Sun 12/67:18 pm -
1 stop4h 28m
Deal found 10/20![Delta logo]()
$232
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:50 am -
Nonstop1h 55m
Wed 11/1812:40 pm -
1 stop4h 15m
Deal found 10/19![Southwest logo]()
$232
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/57:00 am -
1 stop4h 48m
Mon 2/811:51 am -
1 stop5h 46m
Deal found 10/19![Delta logo]()
$261
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/201:39 pm -
1 stop5h 34m
Fri 11/276:40 am -
1 stop5h 40m
Deal found 10/21![Delta logo]()
$262
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/178:35 am -
2 stops9h 50m
Tue 11/245:30 am -
1 stop3h 30m
Deal found 10/20![Southwest logo]()
$265
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/144:03 pm -
1 stop7h 12m
Sun 11/226:26 am -
1 stop5h 08m
Deal found 10/18![American Airlines logo]()
$343
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:35 am -
Nonstop2h 00m
Fri 11/2710:15 am -
Nonstop1h 35m
Deal found 10/21![Southwest logo]()
$266
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:10 am -
1 stop6h 00m
Fri 11/134:40 pm -
2 stops6h 15m
Deal found 10/21![Southwest logo]()
$268
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/108:00 am -
2 stops10h 38m
Thu 11/121:45 pm -
1 stop8h 02m
Deal found 10/19![United Airlines logo]()
$398
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:30 am -
1 stop5h 05m
Mon 11/306:45 pm -
1 stop4h 14m
Deal found 10/16![United Airlines logo]()
$403
This Southwest deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:50 am -
1 stop6h 10m
Thu 11/123:35 pm -
1 stop7h 10m
Deal found 10/18![Southwest logo]()
$294
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/138:00 am -
1 stop5h 20m
Sun 11/156:54 pm -
1 stop4h 52m
Deal found 10/21![Delta logo]()
$357
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/910:21 am -
1 stop5h 13m
Tue 1/127:30 am -
1 stop4h 43m
Deal found 10/18![United Airlines logo]()
$439
This Southwest deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/228:15 pm -
Nonstop1h 45m
Mon 12/285:35 am -
1 stop5h 00m
Deal found 10/18![Southwest logo]()
$313
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/247:28 pm -
1 stop5h 10m
Mon 1/43:17 pm -
2 stops7h 13m
Deal found 10/18![United Airlines logo]()
$442
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/207:30 pm -
1 stop6h 10m
Mon 11/232:35 pm -
1 stop5h 45m
Deal found 10/19![Southwest logo]()
$321
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:10 am -
2 stops9h 35m
Sun 12/135:45 am -
2 stops8h 18m
Deal found 10/19![United Airlines logo]()
$468
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2011:15 am -
2 stops7h 35m
Tue 12/226:15 pm -
1 stop3h 20m
Deal found 10/19![Southwest logo]()
$357
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/44:03 pm -
1 stop7h 12m
Sun 11/86:15 am -
1 stop5h 13m
Deal found 10/20![American Airlines logo]()
$712
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/184:25 pm -
1 stop6h 45m
Wed 11/253:20 pm -
2 stops8h 35m
Deal found 10/19![Southwest logo]()
$367
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:50 am -
2 stops11h 19m
Mon 11/91:25 pm -
2 stops9h 05m
Deal found 10/21![United Airlines logo]()
$539
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/285:20 am -
1 stop6h 20m
Mon 1/45:35 am -
1 stop3h 45m
Deal found 10/20![Southwest logo]()
$382
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/172:07 pm -
1 stop4h 58m
Fri 11/206:40 pm -
2 stops18h 38m
Deal found 10/19![United Airlines logo]()
$585
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/77:25 pm -
1 stop5h 05m
Fri 12/113:15 pm -
2 stops7h 15m
Deal found 10/20![United Airlines logo]()
$589
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/48:00 am -
3 stops15h 58m
Sun 11/88:00 am -
1 stop24h 30m
Deal found 10/20![United Airlines logo]()
$1,064
Last-minute flights from Pittsburgh to MissouriDiscover last-minute flight deals from Pittsburgh to Missouri. Data last updated October 22, 2026 and is based on user searches.
Discover last-minute flight deals from Pittsburgh to Missouri. Data last updated October 22, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:50 am -
1 stop6h 10m
Thu 11/123:35 pm -
1 stop7h 10m
Deal found 10/19![Southwest logo]()
$267
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/114:03 pm -
1 stop4h 19m
Wed 11/181:20 pm -
1 stop6h 37m
Deal found 10/19![American Airlines logo]()
$219
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:50 am -
Nonstop1h 55m
Wed 11/1812:40 pm -
1 stop4h 15m
Deal found 10/19![Southwest logo]()
$232
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/123:14 pm -
1 stop7h 28m
Fri 11/136:00 pm -
1 stop3h 49m
Deal found 10/21![Delta logo]()
$233
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:50 am -
Nonstop1h 55m
Fri 11/137:55 pm -
Nonstop1h 40m
Deal found 10/21![Southwest logo]()
$243
This Southwest deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/164:25 pm -
1 stop6h 45m
Mon 11/232:35 pm -
1 stop5h 45m
Deal found 10/18![Southwest logo]()
$288
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:30 pm -
Nonstop1h 55m
Wed 11/253:55 pm -
1 stop6h 55m
Deal found 10/19![Southwest logo]()
$216
This Frontier deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:27 pm -
1 stop18h 58m
Mon 11/236:05 pm -
1 stop22h 59m
Deal found 10/19![Frontier logo]()
$174
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:50 am -
Nonstop1h 55m
Sat 11/219:50 am -
Nonstop1h 35m
Deal found 10/20![Southwest logo]()
$224
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/194:00 pm -
1 stop7h 15m
Mon 11/234:40 pm -
2 stops6h 25m
Deal found 10/19![Southwest logo]()
$237
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/201:39 pm -
1 stop5h 34m
Fri 11/276:40 am -
1 stop5h 40m
Deal found 10/21![Delta logo]()
$262
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:45 am -
Nonstop1h 55m
Tue 12/16:15 pm -
Nonstop1h 40m
Deal found 10/20![Southwest logo]()
$212
One-way flights from Pittsburgh to MissouriSearch for one-way flight options from Pittsburgh to Missouri. Find affordable one-way fares based on user searches. Data last updated October 22, 2026.
Search for one-way flight options from Pittsburgh to Missouri. Find affordable one-way fares based on user searches. Data last updated October 22, 2026.
This Expedia deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:59 pm -
1 stop6h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Frontier logo]()
$90
This Frontier deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1911:43 am -
1 stop12h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Frontier logo]()
$96
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:50 am -
Nonstop1h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Southwest logo]()
$106
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/218:20 pm -
Nonstop1h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Southwest logo]()
$112
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:50 am -
Nonstop1h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Southwest logo]()
$122
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/34:00 pm -
1 stop6h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Southwest logo]()
$141
This deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/217:37 pm -
1 stop4h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![United Airlines logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/112:53 pm -
2 stops25h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/18![Multiple Airlines logo]()
$166
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/267:59 pm -
1 stop4h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Delta logo]()
$177
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:45 am -
3 stops34h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$185
This Southwest deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/154:00 pm -
1 stop6h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![Southwest logo]()
$185
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/288:29 pm -
1 stop4h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![American Airlines logo]()
$219
Find flight deals from Pittsburgh to Missouri
Keep the following information in mind while searching for Pittsburgh to Missouri flight deals. Data was last updated October 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $174 (Frontier) |
One-way from | $90 (Expedia) |
Popular in | June |
Cheapest in | October |
Average price | $267 |
Good round-trip deal | $308 or less |
Good one-way deal | $217 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Pittsburgh to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 22, 2026.
Use the filters below to find and compare flights from Pittsburgh to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PittsburghSt. Louis
PIT Pittsburgh - STL Lambert-St Louis
PITSTL
Pittsburgh
Wed 11/18
6:50 am-7:45 am
Nonstop1h 55m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$106
PittsburghSt. Louis
PIT Pittsburgh - STL Lambert-St Louis
PITSTL
Pittsburgh
Sat 11/21
6:30 am-12:12 pm
1 stop6h 42m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$110
PittsburghSt. Louis
PIT Pittsburgh - STL Lambert-St Louis
PITSTL
Pittsburgh
Thu 11/19
6:50 am-7:45 am
Nonstop1h 55m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$112
PittsburghKansas City
PIT Pittsburgh - MCI Kansas City
PITMCI
Pittsburgh
Thu 12/3
4:00 pm-9:15 pm
1 stop6h 15m
Kansas City
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$141
PittsburghSt. Louis
PIT Pittsburgh - STL Lambert-St Louis
PITSTL
Pittsburgh
Sat 12/26
7:59 pm-11:55 pm
1 stop4h 56m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$177
PittsburghSt. Louis
PIT Pittsburgh - STL Lambert-St Louis
PITSTL
Pittsburgh
Thu 10/29
9:00 am-1:31 pm
2 stops29h 31m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$177
PittsburghKansas City
PIT Pittsburgh - MCI Kansas City
PITMCI
Pittsburgh
Tue 12/15
4:00 pm-9:15 pm
1 stop6h 15m
Kansas City
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$185
PittsburghSt. Louis
PIT Pittsburgh - STL Lambert-St Louis
PITSTL
Pittsburgh
Sat 12/26
8:35 pm-9:25 pm
Nonstop1h 50m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$207
PittsburghSt. Louis
PIT Pittsburgh - STL Lambert-St Louis
PITSTL
Pittsburgh
Wed 11/18
6:30 pm-7:25 pm
Nonstop1h 55m
Lambert-St Louis
Wed 11/25
3:55 pm-11:50 pm
1 stop6h 55m
$216
PittsburghKansas City
PIT Pittsburgh - MCI Kansas City
PITMCI
Pittsburgh
Sat 11/28
8:29 pm-12:24 am
1 stop4h 55m
Kansas City
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$219
Showing 1-10 of 48 resultsSorted by cheapest first
Best time to book a flight from Pittsburgh to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Pittsburgh with our price prediction graph.
PIT-STL
PIT-MCI
PIT-SGF
PIT-COU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Pittsburgh to Missouri
PIT-USMO
PIT-STL
PIT-MCI
PIT-SGF
PIT-COU
What is the cheapest month to book a flight from Pittsburgh to Missouri?
Currently, January is the cheapest month in which you can book a flight from Pittsburgh to Missouri (average of $316). Flying from Pittsburgh to Missouri in June is currently the most expensive (average of $499). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PIT to MO?
Find hourly flight availability from Pittsburgh to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 22, 2026.
It’s optimal to fly from Pittsburgh to Missouri at noon. By choosing this option you can save up to 17% on the cost of your flight, compared to a flight in the morning.
How much does it cost to fly round-trip from Pittsburgh to Missouri?
Airfare is below average for this route at the moment.
Pittsburgh to Missouri flights typically cost between $238 and $338 in November.The cheapest round-trip price found within the last 5 days was $174 on Frontier (Nov 19-Nov 23).
How far ahead should I book a flight from Pittsburgh to Missouri?
The best time to book flights from Pittsburgh to Missouri is 70 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated October 22, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Pittsburgh to Missouri by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Comfort
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.4
Food
7.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Overall
7.9
Comfort
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.4
Food
7.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Overall
7.9
Comfort
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.4
Food
7.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Overall
7.9
Comfort
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.4
Food
7.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Overall
7.9
Comfort
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.4
Food
7.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Related info for your journey
Find useful and relevant information for your journey from Pittsburgh to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for Pittsburgh to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Pittsburgh to Missouri by cabin class
Find flights from Pittsburgh to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Pittsburgh and Missouri flights
Browse other Pittsburgh and Missouri flight options. Last updated on October 22, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Pittsburgh to Missouri flights
Consider these flights traveling from Pittsburgh to Missouri.
Top 4 airlines flying from Pittsburgh to Missouri
Discover the top 4 airlines that operate flights from Pittsburgh to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$170 | Average$408 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$188 | Average$414 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$217 | Average$399 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$263 | Average$430 | FlexibilityNo cancel fee | On-time69% |