$69+ Cheap flights from Pittsburgh (PIT) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/3. Fares are subject to change and may not be available on all flights or dates of travel.
PIT — STL
Mar 4 — Mar 111
1 adult, Economy
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Find cheap flights from Pittsburgh to Missouri with Cheapflights
1. Tell us where you want to go
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Cheapest flights from Pittsburgh to MissouriExplore the most affordable flight options available from Pittsburgh to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 2, 2026.
Explore the most affordable flight options available from Pittsburgh to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 2, 2026.
This Expedia deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/25:45 am
PIT
- MCI
1 stop10h 44m
Spirit Airlines
Wed 3/44:24 pm
MCI
- PIT
1 stop6h 01m
Spirit Airlines
Deal found 1/29![Spirit Airlines logo]()
$126
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/45:00 am
PIT
- STL
1 stop6h 05m
Southwest
Sat 4/115:35 pm
STL
- PIT
1 stop4h 25m
Southwest
Deal found 2/1![Southwest logo]()
$159
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/46:30 am
PIT
- STL
1 stop4h 33m
American Airlines
Sat 4/118:00 am
STL
- PIT
1 stop7h 48m
American Airlines
Deal found 2/1![American Airlines logo]()
$185
This Priceline deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/146:00 am
PIT
- MCI
1 stop6h 29m
Spirit Airlines
Thu 3/1912:24 pm
MCI
- PIT
1 stop10h 00m
Spirit Airlines
Deal found 1/30![Spirit Airlines logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/116:00 am
PIT
- MCI
1 stop30h 29m
Multiple Airlines
Mon 3/166:20 pm
MCI
- PIT
2 stops26h 18m
Multiple Airlines
Deal found 1/31![Multiple Airlines logo]()
$212
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/116:00 am
PIT
- MCI
1 stop30h 29m
Spirit Airlines
Tue 3/1712:24 pm
MCI
- PIT
1 stop8h 14m
Spirit Airlines
Deal found 1/31![Spirit Airlines logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2410:45 am
PIT
- MCI
1 stop25h 44m
Spirit Airlines
Fri 3/2712:24 pm
MCI
- PIT
1 stop20h 14m
Spirit Airlines
Deal found 1/30![Spirit Airlines logo]()
$229
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/116:22 pm
PIT
- STL
1 stop13h 55m
Multiple Airlines
Wed 3/1811:32 am
STL
- PIT
2 stops21h 06m
Multiple Airlines
Deal found 1/31![Multiple Airlines logo]()
$246
This Kiwi.com deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/156:00 am
PIT
- MCI
1 stop30h 29m
Multiple Airlines
Wed 3/1811:45 am
MCI
- PIT
2 stops20h 53m
Multiple Airlines
Deal found 1/30![Multiple Airlines logo]()
$249
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/246:00 am
PIT
- STL
1 stop7h 33m
American Airlines
Sat 2/286:06 am
STL
- PIT
1 stop5h 35m
American Airlines
Deal found 2/1![American Airlines logo]()
$255
This Kiwi.com deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1210:45 am
PIT
- MCI
1 stop25h 44m
Multiple Airlines
Mon 3/166:20 pm
MCI
- PIT
2 stops26h 18m
Multiple Airlines
Deal found 1/30![Multiple Airlines logo]()
$256
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:22 pm
PIT
- STL
1 stop13h 40m
Multiple Airlines
Mon 3/94:51 pm
STL
- PIT
1 stop22h 48m
Multiple Airlines
Deal found 1/31![Multiple Airlines logo]()
$265
Best flights from Pittsburgh to MissouriDiscover carefully curated flight deals from Pittsburgh to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 2, 2026.
Discover carefully curated flight deals from Pittsburgh to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 2, 2026.
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/45:00 am
PIT
- STL
1 stop6h 05m
Southwest
Sat 4/115:35 pm
STL
- PIT
1 stop4h 25m
Southwest
Deal found 2/1![Southwest logo]()
$159
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/46:30 am
PIT
- STL
1 stop4h 33m
American Airlines
Sat 4/118:00 am
STL
- PIT
1 stop7h 48m
American Airlines
Deal found 2/1![American Airlines logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/116:00 am
PIT
- MCI
1 stop30h 29m
Spirit Airlines
Tue 3/1712:24 pm
MCI
- PIT
1 stop8h 14m
Spirit Airlines
Deal found 1/31![Spirit Airlines logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/1310:45 am
PIT
- MCI
1 stop25h 44m
Multiple Airlines
Mon 3/166:20 pm
MCI
- PIT
2 stops26h 18m
Multiple Airlines
Deal found 1/31![Multiple Airlines logo]()
$262
This United Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/24:47 pm
PIT
- MCI
1 stop6h 53m
United Airlines
Wed 3/412:37 pm
MCI
- PIT
1 stop5h 14m
United Airlines
Deal found 1/30![United Airlines logo]()
$304
This Delta deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:30 am
PIT
- STL
1 stop4h 12m
Delta
Sun 4/195:59 pm
STL
- PIT
1 stop3h 57m
Delta
Deal found 1/31![Delta logo]()
$316
This Mytrip deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/1410:45 am
PIT
- MCI
2 stops14h 08m
Spirit Airlines
Thu 3/1912:24 pm
MCI
- PIT
1 stop10h 00m
Spirit Airlines
Deal found 1/30![Spirit Airlines logo]()
$241
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1210:45 am
PIT
- MCI
1 stop25h 44m
Multiple Airlines
Mon 3/166:20 pm
MCI
- PIT
2 stops26h 18m
Multiple Airlines
Deal found 1/31![Multiple Airlines logo]()
$262
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/186:22 am
PIT
- SGF
1 stop5h 56m
American Airlines
Wed 3/256:00 pm
SGF
- PIT
1 stop4h 18m
American Airlines
Deal found 2/1![American Airlines logo]()
$269
This Southwest deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:00 pm
PIT
- STL
1 stop3h 45m
Southwest
Mon 5/42:25 pm
STL
- PIT
1 stop6h 40m
Southwest
Deal found 1/31![Southwest logo]()
$280
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/55:45 am
PIT
- STL
1 stop19h 14m
Multiple Airlines
Mon 3/94:51 pm
STL
- PIT
1 stop22h 48m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$266
This American Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:54 am
PIT
- STL
1 stop5h 15m
American Airlines
Sun 4/196:00 am
STL
- PIT
1 stop4h 04m
American Airlines
Deal found 1/30![American Airlines logo]()
$280
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/165:20 am
PIT
- STL
1 stop9h 25m
Southwest
Sun 4/192:10 pm
STL
- PIT
1 stop6h 20m
Southwest
Deal found 2/1![Southwest logo]()
$285
This Priceline deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/275:15 pm
PIT
- MCI
1 stop7h 44m
Spirit Airlines
Sat 5/912:12 pm
MCI
- PIT
1 stop10h 30m
Spirit Airlines
Deal found 1/29![Spirit Airlines logo]()
$286
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/187:00 am
PIT
- SGF
1 stop4h 46m
United Airlines
Wed 3/257:45 am
SGF
- PIT
2 stops10h 16m
United Airlines
Deal found 2/1![United Airlines logo]()
$321
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2010:20 am
PIT
- SGF
1 stop5h 40m
Delta
Mon 4/276:55 pm
SGF
- PIT
1 stop4h 36m
Delta
Deal found 2/1![Delta logo]()
$334
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/17:09 pm
PIT
- SGF
1 stop4h 26m
American Airlines
Sun 3/86:15 pm
SGF
- PIT
1 stop5h 21m
American Airlines
Deal found 2/1![American Airlines logo]()
$294
This United Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/110:45 am
PIT
- MCI
1 stop4h 41m
United Airlines
Tue 3/33:22 pm
MCI
- PIT
1 stop4h 32m
United Airlines
Deal found 1/29![United Airlines logo]()
$332
This Kiwi.com deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/271:22 pm
PIT
- MCI
2 stops35h 11m
Multiple Airlines
Sat 5/912:12 pm
MCI
- PIT
1 stop10h 30m
Multiple Airlines
Deal found 1/29![Multiple Airlines logo]()
$307
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/17:05 pm
PIT
- STL
Nonstop1h 55m
Southwest
Mon 4/67:40 pm
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 2/1![Southwest logo]()
$319
This Mytrip deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/159:09 pm
PIT
- MCI
1 stop14h 21m
Spirit Airlines
Sun 4/1912:12 pm
MCI
- PIT
1 stop10h 30m
Spirit Airlines
Deal found 1/30![Spirit Airlines logo]()
$330
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1210:07 am
PIT
- SGF
1 stop5h 28m
Delta
Sat 5/164:00 pm
SGF
- PIT
1 stop4h 37m
Delta
Deal found 2/1![Delta logo]()
$394
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:25 am
PIT
- MCI
1 stop4h 25m
Southwest
Sat 4/253:10 pm
MCI
- PIT
2 stops6h 50m
Southwest
Deal found 2/1![Southwest logo]()
$326
This deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1110:49 am
PIT
- SGF
1 stop4h 49m
United Airlines
Sun 2/157:55 am
SGF
- PIT
1 stop4h 11m
United Airlines
Deal found 2/1![United Airlines logo]()
$379
This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:55 pm
PIT
- SGF
1 stop17h 44m
United Airlines
Mon 4/276:30 pm
SGF
- PIT
1 stop4h 23m
United Airlines
Deal found 1/31![United Airlines logo]()
$390
Last-minute flights from Pittsburgh to MissouriDiscover last-minute flight deals from Pittsburgh to Missouri. Data last updated February 2, 2026 and is based on user searches.
Discover last-minute flight deals from Pittsburgh to Missouri. Data last updated February 2, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/56:19 am
PIT
- STL
1 stop4h 15m
Delta
Tue 2/106:35 am
STL
- PIT
1 stop5h 52m
Delta
Deal found 1/31![Delta logo]()
$351
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/101:15 pm
PIT
- STL
1 stop6h 45m
Southwest
Wed 2/1110:15 am
STL
- PIT
2 stops6h 25m
Southwest
Deal found 2/1![Southwest logo]()
$356
This United Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/102:09 pm
PIT
- JLN
1 stop4h 25m
United Airlines
Sat 2/148:54 am
JLN
- PIT
1 stop7h 09m
United Airlines
Deal found 1/30![United Airlines logo]()
$374
This Kiwi.com deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/145:45 pm
PIT
- MCI
2 stops16h 44m
Multiple Airlines
Wed 2/184:24 pm
MCI
- PIT
1 stop23h 15m
Multiple Airlines
Deal found 1/30![Multiple Airlines logo]()
$341
This Kiwi.com deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/156:00 am
PIT
- STL
2 stops25h 51m
Multiple Airlines
Thu 2/193:49 pm
STL
- PIT
1 stop17h 45m
Multiple Airlines
Deal found 1/30![Multiple Airlines logo]()
$322
This Mytrip deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/159:09 pm
PIT
- MCI
1 stop14h 21m
Spirit Airlines
Sun 4/1912:12 pm
MCI
- PIT
1 stop10h 30m
Spirit Airlines
Deal found 1/30![Spirit Airlines logo]()
$330
This Southwest deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/151:25 pm
PIT
- STL
1 stop3h 30m
Southwest
Thu 2/1912:20 pm
STL
- PIT
1 stop5h 05m
Southwest
Deal found 1/30![Southwest logo]()
$346
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/196:00 am
PIT
- STL
2 stops25h 51m
Multiple Airlines
Sun 2/223:49 pm
STL
- PIT
1 stop20h 35m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$340
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/191:25 pm
PIT
- STL
1 stop3h 30m
Southwest
Sun 2/227:55 am
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 2/1![Southwest logo]()
$358
This American Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/217:41 am
PIT
- STL
1 stop5h 52m
American Airlines
Sat 3/76:36 pm
STL
- PIT
1 stop4h 35m
American Airlines
Deal found 1/31![American Airlines logo]()
$307
This Southwest deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/215:35 am
PIT
- STL
2 stops8h 55m
Southwest
Sat 3/76:40 am
STL
- PIT
1 stop3h 50m
Southwest
Deal found 1/31![Southwest logo]()
$354
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/246:00 am
PIT
- STL
1 stop7h 33m
American Airlines
Sat 2/286:06 am
STL
- PIT
1 stop5h 35m
American Airlines
Deal found 2/1![American Airlines logo]()
$255
One-way flights from Pittsburgh to MissouriSearch for one-way flight options from Pittsburgh to Missouri. Find affordable one-way fares based on user searches. Data last updated February 2, 2026.
Search for one-way flight options from Pittsburgh to Missouri. Find affordable one-way fares based on user searches. Data last updated February 2, 2026.
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/35:45 am
PIT
- STL
1 stop17h 42m
Multiple Airlines
Deal found 1/31![Multiple Airlines logo]()
$69
This Delta deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/256:00 am
PIT
- STL
1 stop6h 02m
Delta
Deal found 1/31![Delta logo]()
$89
This Delta deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/273:55 pm
PIT
- STL
1 stop5h 47m
Delta
Deal found 1/31![Delta logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/285:45 pm
PIT
- STL
1 stop7h 14m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$118
This American Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/24:01 pm
PIT
- STL
2 stops8h 47m
American Airlines
Deal found 1/31![American Airlines logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/256:00 am
PIT
- STL
3 stops42h 59m
Multiple Airlines
Deal found 1/31![Multiple Airlines logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/3010:45 am
PIT
- STL
2 stops24h 47m
Multiple Airlines
Deal found 1/31![Multiple Airlines logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:00 am
PIT
- STL
2 stops29h 30m
Multiple Airlines
Deal found 1/31![Multiple Airlines logo]()
$140
This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/287:00 am
PIT
- STL
1 stop15h 05m
United Airlines
Deal found 1/31![United Airlines logo]()
$142
This Priceline deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/196:00 am
PIT
- MCI
1 stop6h 29m
Spirit Airlines
Deal found 1/29![Spirit Airlines logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:00 am
PIT
- SGF
1 stop9h 51m
Allegiant Air
Deal found 2/1![Allegiant Air logo]()
$220
This American Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:30 am
PIT
- SGF
1 stop4h 20m
American Airlines
Deal found 1/31![American Airlines logo]()
$249
Find flight deals from Pittsburgh to Missouri
Keep the following information in mind while searching for Pittsburgh to Missouri flight deals. Data was last updated February 2, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $148 (Orbitz) |
One-way from | $69 (Kiwi.com) |
Popular in | January |
Cheapest in | April |
Average price | $321 |
Good round-trip deal | $343 or less |
Good one-way deal | $171 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Pittsburgh to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 2, 2026.
Use the filters below to find and compare flights from Pittsburgh to Missouri that are best for you.
Fly from
Pittsburgh
Fly to
Missouri
Route
Depart
Return
Price
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Sat 4/4
5:00 am-10:05 am
1 stop6h 05m
Lambert-St Louis
Sat 4/11
5:35 pm-11:00 pm
1 stop4h 25m
$159
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Sat 4/4
6:30 am-10:03 am
1 stop4h 33m
Lambert-St Louis
Sat 4/11
8:00 am-4:48 pm
1 stop7h 48m
$185
PittsburghKansas City
PIT - MCI
PITMCI
Pittsburgh
Wed 3/11
6:00 am-11:29 am
1 stop30h 29m
Kansas City
Tue 3/17
12:24 pm-9:38 pm
1 stop8h 14m
$224
PittsburghKansas City
PIT - MCI
PITMCI
Pittsburgh
Sat 3/14
10:45 am-11:53 pm
2 stops14h 08m
Kansas City
Thu 3/19
12:24 pm-11:24 pm
1 stop10h 00m
$241
PittsburghKansas City
PIT - MCI
PITMCI
Pittsburgh
Fri 3/13
10:45 am-11:29 am
1 stop25h 44m
Kansas City
Mon 3/16
6:20 pm-9:38 pm
2 stops26h 18m
$262
PittsburghKansas City
PIT - MCI
PITMCI
Pittsburgh
Thu 3/12
10:45 am-11:29 am
1 stop25h 44m
Kansas City
Mon 3/16
6:20 pm-9:38 pm
2 stops26h 18m
$262
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Thu 3/5
5:45 am-11:59 pm
1 stop19h 14m
Lambert-St Louis
Mon 3/9
4:51 pm-4:39 pm
1 stop22h 48m
$266
PittsburghSpringfield
PIT - SGF
PITSGF
Pittsburgh
Wed 3/18
6:22 am-11:18 am
1 stop5h 56m
Springfield-Branson
Wed 3/25
6:00 pm-11:18 pm
1 stop4h 18m
$269
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Fri 5/1
8:00 pm-10:45 pm
1 stop3h 45m
Lambert-St Louis
Mon 5/4
2:25 pm-10:05 pm
1 stop6h 40m
$280
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Thu 4/16
6:54 am-11:09 am
1 stop5h 15m
Lambert-St Louis
Sun 4/19
6:00 am-11:04 am
1 stop4h 04m
$280
Showing 1-10 of 42 results
Best time to book a flight from Pittsburgh to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Pittsburgh with our price prediction graph.
PIT-STL
PIT-MCI
PIT-SGF
PIT-JLN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Pittsburgh to Missouri
PIT-USMO
PIT-STL
PIT-MCI
PIT-SGF
PIT-JLN
What is the cheapest month to book a flight from Pittsburgh to Missouri?
Currently, November is the cheapest month in which you can book a flight from Pittsburgh to Missouri (average of $156). Flying from Pittsburgh to Missouri in July is currently the most expensive (average of $269). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PIT to MO?
Find hourly flight availability from Pittsburgh to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 2, 2026.
It’s optimal to fly from Pittsburgh to Missouri at noon. By choosing this option you can save up to 28% on the cost of your flight, compared to a flight in the morning.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated February 2, 2026.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Pittsburgh to Missouri by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Pittsburgh to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes for Pittsburgh to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Top 4 airlines flying from Pittsburgh to Missouri
Discover the top 4 airlines that operate flights from Pittsburgh to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$170 | Average$355 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$241 | Average$382 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$248 | Average$382 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$277 | Average$402 | FlexibilityNo cancel fee | On-time69% |