HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Missouri

$66+ Cheap flights from Irvine, CA to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/17. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — MCI
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Irvine to Missouri with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Irvine to Missouri

Cheapest flights from Irvine to Missouri
Explore the most affordable flight options available from Irvine to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:22 pmLAX - MCI
1 stop18h 36mMultiple Airlines
Sun 1/44:32 pmMCI - LAX
2 stops16h 46mMultiple Airlines
Deal found 12/16$213
This Frontier deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/299:15 amLAX - STL
1 stop8h 52mFrontier
Fri 1/28:42 pmSTL - LAX
1 stop12h 56mFrontier
Deal found 12/17$234
This CheapOair deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/233:30 pmLAX - STL
1 stop22h 54mFrontier
Sun 1/410:10 pmSTL - LAX
1 stop24h 21mFrontier
Deal found 12/16$235
This Flightnetwork deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2410:45 pmLAX - STL
1 stop8h 55mFrontier
Sat 1/310:10 pmSTL - LAX
1 stop16h 06mFrontier
Deal found 12/15$240
This Kiwi.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2810:03 pmLAX - STL
1 stop21h 22mFrontier
Mon 1/510:10 pmSTL - LAX
1 stop14h 26mFrontier
Deal found 12/17$242
This Kiwi.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/303:30 pmLAX - STL
1 stop22h 54mFrontier
Mon 1/510:10 pmSTL - LAX
1 stop14h 26mFrontier
Deal found 12/17$247
This Frontier deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/301:11 pmLAX - STL
1 stop6h 14mFrontier
Fri 1/28:42 pmSTL - LAX
1 stop12h 56mFrontier
Deal found 12/17$254
This CheapOair deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/201:13 pmLAX - STL
1 stop6h 12mFrontier
Fri 1/28:42 pmSTL - LAX
1 stop12h 56mFrontier
Deal found 12/16$255
This Travelocity deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/208:58 pmLAX - MCI
1 stop20h 53mFrontier
Mon 1/58:45 pmMCI - LAX
1 stop17h 57mFrontier
Deal found 12/16$257
This Frontier deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/288:58 pmLAX - STL
1 stop11h 04mFrontier
Fri 1/28:42 pmSTL - LAX
1 stop12h 56mFrontier
Deal found 12/17$258
This CheapOair deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:59 pmLAX - STL
1 stop20h 34mFrontier
Fri 1/28:42 pmSTL - LAX
1 stop12h 56mFrontier
Deal found 12/16$259
This Kiwi.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/242:22 pmLAX - MCI
1 stop18h 36mFrontier
Thu 1/88:23 pmMCI - LAX
1 stop5h 45mFrontier
Deal found 12/17$262

Find flight deals from Irvine to Missouri

Keep the following information in mind while searching for Irvine to Missouri flight deals. Data was last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$203
(CheapOair)

One-way from

$66
(WAYA)

Popular in

June

Cheapest in

October

Average price

$420
Provider with most accurate pricing for Los Angeles-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Los Angeles-Lambert-St Louis flights.
Search Deals
From Irvine to Missouri
Search Deals
One-way flight from Irvine to Missouri
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($21 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease ($4 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Irvine to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Irvine to Missouri that are best for you.

Fly from

Irvine

Fly to

Missouri

Route

Depart

Return

Price

Los AngelesSt. Louis

LAX - STL

LAXSTL

Los Angeles

Mon 2/2

1:13 pm-8:50 pm

1 stop5h 37m

Lambert-St Louis

Fri 2/6

7:39 pm-12:30 am

1 stop6h 51m

$217

Los AngelesSt. Louis

LAX - STL

LAXSTL

Los Angeles

Tue 12/30

3:30 pm-10:02 am

2 stops16h 32m

Lambert-St Louis

Mon 1/5

10:10 pm-10:36 am

1 stop14h 26m

$250

Los AngelesSpringfield

LAX - SGF

LAXSGF

Los Angeles

Sat 1/17

5:00 am-12:45 pm

1 stop5h 45m

Springfield-Branson

Tue 1/20

5:03 pm-9:18 pm

1 stop6h 15m

$257

Los AngelesKansas City

LAX - MCI

LAXMCI

Los Angeles

Tue 2/24

1:05 am-10:30 am

3 stops31h 25m

Kansas City

Sun 3/1

11:26 am-11:50 pm

1 stop14h 24m

$261

Los AngelesSpringfield

LAX - SGF

LAXSGF

Los Angeles

Tue 1/20

12:20 pm-9:46 pm

1 stop7h 26m

Springfield-Branson

Wed 1/28

5:00 pm-11:51 pm

1 stop8h 51m

$273

Los AngelesSt. Louis

LAX - STL

LAXSTL

Los Angeles

Wed 3/4

11:45 am-12:25 am

2 stops10h 40m

Lambert-St Louis

Tue 3/10

2:22 pm-10:47 pm

2 stops10h 25m

$274

Los AngelesSt. Louis

LAX - STL

LAXSTL

Los Angeles

Sat 1/17

9:55 am-11:25 pm

2 stops11h 30m

Lambert-St Louis

Sat 1/24

6:40 am-4:38 pm

2 stops11h 58m

$274

Los AngelesColumbia

LAX - COU

LAXCOU

Los Angeles

Wed 2/18

12:43 pm-9:33 pm

1 stop6h 50m

Columbia Regional

Sat 2/21

3:10 pm-10:59 pm

1 stop9h 49m

$278

Los AngelesKansas City

LAX - MCI

LAXMCI

Los Angeles

Wed 12/24

3:30 pm-10:58 am

2 stops17h 28m

Kansas City

Thu 1/8

8:23 pm-12:08 am

1 stop5h 45m

$279

Los AngelesSpringfield

LAX - SGF

LAXSGF

Los Angeles

Fri 1/23

5:50 am-1:58 pm

1 stop6h 08m

Springfield-Branson

Sun 1/25

7:45 am-1:30 pm

1 stop7h 45m

$289

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/17

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Irvine to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Irvine with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Irvine to Missouri

What is the cheapest month to book a flight from Irvine to Missouri?

Currently, June is the cheapest month in which you can book a flight from Irvine to Missouri (average of $60). Flying from Irvine to Missouri in November is currently the most expensive (average of $149). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IR9 to MO?

Find hourly flight availability from Irvine to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

One of the essential ways to save on airfare from Irvine to Missouri is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 42% on airfare.

What is the cheapest day to fly from Irvine to Missouri?

Use this chart to determine the cheapest time to fly round-trip from Irvine to Missouri. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Irvine to Missouri flight should consider departing on Tuesday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated December 18, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and American Airlines from Irvine to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
7.9
Good
4,250 reviews

Entertainment

7.5

Crew

8.6

Overall

7.9

Boarding

8.1

Food

7.0

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
Southwest
7.9
Good
4,250 reviews
Southwest
7.9
Good
4,250 reviews

Entertainment

7.5

Crew

8.6

Overall

7.9

Boarding

8.1

Food

7.0

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
Delta
7.9
Good
8,005 reviews
Southwest
7.9
Good
4,250 reviews

Entertainment

7.5

Crew

8.6

Overall

7.9

Boarding

8.1

Food

7.0

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
American Airlines
7.2
Good
11,054 reviews
Southwest
7.9
Good
4,250 reviews

Entertainment

7.5

Crew

8.6

Overall

7.9

Boarding

8.1

Food

7.0

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
Spirit Airlines
6.3
Okay
8,190 reviews
Southwest
7.9
Good
4,250 reviews

Entertainment

7.5

Crew

8.6

Overall

7.9

Boarding

8.1

Food

7.0

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
Frontier
5.8
Fair
3,081 reviews
Southwest
7.9
Good
4,250 reviews

Entertainment

7.5

Crew

8.6

Overall

7.9

Boarding

8.1

Food

7.0

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Related info for your journey

Find useful and relevant information for your journey from Irvine to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Irvine to Missouri flight route?

    Within the past month, 24 users have taken a look at flights from Irvine to Missouri.

  • How long is the flight from Irvine to Missouri?

    For as low as $217, Frontier can have you in Missouri from Irvine in 5h 37m. There are 1588 mi between Irvine and Missouri. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Irvine to Missouri?

    Most travelers choose Los Angeles - Kansas City, Los Angeles - Lambert-St Louis or Los Angeles - Springfield-Branson when deciding on the best route from Irvine to Missouri.

  • What are the most reliable airlines from Irvine to Missouri?

    Before booking your flight to Missouri from Irvine, check out the most reliable airlines to get you to your destination on time: Air France (100%), Aeromexico (88%), Delta( 86%).

  • What are the cheapest flights from Irvine to Missouri?

    While on average a flight from Irvine to Missouri is generally $361, our data shows the cheapest flight currently is $137. When looking at the most popular route, (Los Angeles - Kansas City), you can expect to pay $140 for that flight.

  • Can I find deals for flights from Irvine to Missouri that include hotel bookings?

    Yes. In addition to deals on Irvine to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Irvine to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Irvine to Missouri.

  • Can I find deals for business class flights from Irvine to Missouri?

    Yes. Cheapflights offers flight deals from Irvine to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Irvine to Missouri?

    Currently, June is the cheapest month in which you can book a flight from Irvine to Missouri (average of $60). Flying from Irvine to Missouri in November is currently the most expensive (average of $149). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Irvine to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
Los Angeles to John F Kennedy Intl flights
Los Angeles to Newark flights
San Francisco to Las Vegas flights
San Francisco to John F Kennedy Intl flights
Los Angeles to Seattle flights
Los Angeles to Honolulu flights
Los Angeles to Dallas/Fort Worth flights
Los Angeles to LaGuardia flights
San Francisco to Newark flights
San Francisco to Honolulu flights
Los Angeles to Las Vegas flights
Los Angeles to Miami flights
Los Angeles to San Francisco flights
San Francisco to Dallas/Fort Worth flights
Los Angeles to Fort Lauderdale flights
Los Angeles to Orlando flights
Burbank to Las Vegas flights
Santa Ana to Las Vegas flights
San Francisco to Los Angeles flights
Los Angeles to O'Hare Intl flights
Los Angeles to Boston flights
San Jose to Las Vegas flights
Ontario to Seattle flights
Ontario to San Francisco flights
San Francisco to LaGuardia flights
Los Angeles to Hobby flights
Los Angeles to Denver flights
San Jose to Los Angeles flights
San Francisco to Ontario flights
Ontario to Dallas/Fort Worth flights
San Francisco to Orlando flights
Oakland to Las Vegas flights
Los Angeles to Salt Lake City flights
Santa Ana to Dallas/Fort Worth flights
San Francisco to Kahului flights
San Diego to John F Kennedy Intl flights
Los Angeles to Reagan-National flights
Los Angeles to Kahului flights
San Francisco to Seattle flights
San Francisco to Miami flights
San Francisco to San Diego flights
Burbank to LaGuardia flights
San Francisco to Sky Harbor Intl flights
Los Angeles to Sky Harbor Intl flights
Ontario to John F Kennedy Intl flights
Los Angeles to George Bush Intcntl flights
San Francisco to Denver flights
Los Angeles to San Jose flights
Los Angeles to Atlanta flights
San Francisco to O'Hare Intl flights

Top 8 airlines flying from Irvine to Missouri

Discover the top 8 airlines that operate flights from Irvine to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$98Average$275FlexibilityNo cancel feeOn-time65%
DeltaCheapest$98Average$382FlexibilityNo cancel feeOn-timeN/A
FrontierCheapest$115Average$218FlexibilityNo cancel feeOn-time62%
Allegiant AirCheapest$140Average$257FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$202Average$464FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$206Average$436FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$248Average$456FlexibilityNo cancel feeOn-time69%
Alaska AirlinesCheapest$257Average$487FlexibilityNo cancel feeOn-time75%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.