$101+ Cheap flights from Irvine, CA to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/8. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — STL
Dec 3 — Dec 101
1 adult, Economy
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Find cheap flights from Irvine to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Irvine to Missouri
Keep the following information in mind while searching for Irvine to Missouri flight deals. Data was last updated November 3, 2025.
Most accurate provider | CheapOair 3 stars |
|---|---|
Most trusted provider | CheapOair 3 stars |
Round-trip from | $162 (Mytrip) |
One-way from | $101 (Kiwi.com) |
Popular in | December |
Cheapest in | April |
Average price | $406 |
Find flight deals from Irvine to Missouri
Cheapest flights from Irvine to MissouriExplore the most affordable flight options available from Irvine to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 3, 2025.
Explore the most affordable flight options available from Irvine to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 3, 2025.
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1512:42 pmLAX - MCI
1 stop21h 04mFrontier
Tue 11/186:49 pmMCI - LAX
1 stop7h 36mFrontier
Deal found 11/3![Frontier logo]()
$167
This Priceline deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/187:00 amLAX - MCI
1 stop8h 19mMultiple Airlines
Fri 11/2112:58 pmMCI - LAX
1 stop10h 01mMultiple Airlines
Deal found 11/1![Multiple Airlines logo]()
$168
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/56:40 amLAX - MCI
1 stop5h 13mMultiple Airlines
Mon 12/86:30 amMCI - LAX
1 stop15h 35mMultiple Airlines
Deal found 11/1![Multiple Airlines logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/56:40 amLAX - MCI
1 stop5h 13mMultiple Airlines
Tue 12/96:30 amMCI - LAX
1 stop15h 35mMultiple Airlines
Deal found 11/1![Multiple Airlines logo]()
$172
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/51:40 pmLAX - STL
2 stops18h 34mFrontier
Mon 12/87:43 pmSTL - LAX
1 stop6h 46mFrontier
Deal found 11/1![Frontier logo]()
$174
This Priceline deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/117:00 amLAX - MCI
1 stop8h 19mFrontier
Tue 11/186:49 pmMCI - LAX
1 stop7h 36mFrontier
Deal found 11/2![Frontier logo]()
$176
This CheapOair deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1312:44 pmLAX - STL
1 stop18h 23mFrontier
Sat 11/157:45 pmSTL - LAX
1 stop6h 40mFrontier
Deal found 10/31![Frontier logo]()
$176
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/56:40 amLAX - MCI
1 stop5h 13mFrontier
Mon 12/812:46 pmMCI - LAX
2 stops33h 19mFrontier
Deal found 11/1![Frontier logo]()
$177
This Booking.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1511:40 amLAX - STL
1 stop19h 27mFrontier
Thu 11/209:54 pmSTL - LAX
1 stop17h 32mFrontier
Deal found 11/2![Frontier logo]()
$178
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/238:58 pmLAX - MCI
1 stop20h 52mFrontier
Tue 12/308:45 pmMCI - LAX
1 stop12h 57mFrontier
Deal found 11/1![Frontier logo]()
$179
This Kiwi.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/159:04 amLAX - STL
2 stops22h 03mMultiple Airlines
Wed 11/197:45 pmSTL - LAX
1 stop6h 40mMultiple Airlines
Deal found 10/31![Multiple Airlines logo]()
$179
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/48:51 pmLAX - MCI
1 stop15h 02mMultiple Airlines
Wed 12/106:30 amMCI - LAX
1 stop15h 35mMultiple Airlines
Deal found 11/2![Multiple Airlines logo]()
$180
Cheapflights Fare Finder
Customize your flight search to find flights from Irvine to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from Irvine to Missouri that are best for you.
Fly from
Irvine
Fly to
Missouri
Route
Depart
Return
Price
Los AngelesSpringfield
LAX - SGF
LAXSGF
Los Angeles
Fri 11/28
12:30 pm-8:46 pm
1 stop6h 16m
Springfield-Branson
Thu 12/4
9:16 am-2:45 pm
1 stop7h 29m
$269
Los AngelesSpringfield
LAX - SGF
LAXSGF
Los Angeles
Fri 12/12
11:59 pm-8:46 am
1 stop6h 47m
Springfield-Branson
Sun 12/14
10:10 am-2:45 pm
1 stop6h 35m
$269
Los AngelesSt. Louis
LAX - STL
LAXSTL
Los Angeles
Mon 12/1
11:15 pm-10:33 pm
1 stop21h 18m
Lambert-St Louis
Tue 12/9
3:30 pm-6:38 pm
2 stops29h 08m
$287
Los AngelesSt. Louis
LAX - STL
LAXSTL
Los Angeles
Wed 11/26
10:05 am-9:58 am
2 stops21h 53m
Lambert-St Louis
Mon 12/1
3:53 pm-10:39 am
1 stop20h 46m
$302
Los AngelesKansas City
LAX - MCI
LAXMCI
Los Angeles
Tue 3/3
7:00 am-4:20 pm
1 stop7h 20m
Kansas City
Wed 3/4
2:55 pm-10:35 pm
1 stop9h 40m
$303
Los AngelesKansas City
LAX - MCI
LAXMCI
Los Angeles
Tue 3/3
7:00 am-4:20 pm
1 stop7h 20m
Kansas City
Wed 3/4
2:55 pm-8:25 pm
1 stop7h 30m
$303
Los AngelesSt. Louis
LAX - STL
LAXSTL
Los Angeles
Tue 12/2
7:35 am-1:10 pm
Nonstop3h 35m
Lambert-St Louis
Sat 12/6
6:15 am-11:40 am
1 stop7h 25m
$305
Los AngelesSt. Louis
LAX - STL
LAXSTL
Los Angeles
Thu 12/4
7:35 am-1:10 pm
Nonstop3h 35m
Lambert-St Louis
Tue 12/9
10:15 am-12:25 pm
Nonstop4h 10m
$310
Los AngelesSt. Louis
LAX - STL
LAXSTL
Los Angeles
Mon 12/1
5:10 am-10:50 am
Nonstop3h 40m
Lambert-St Louis
Wed 12/3
6:35 pm-8:40 pm
Nonstop4h 05m
$310
Los AngelesSt. Louis
LAX - STL
LAXSTL
Los Angeles
Thu 12/4
7:35 am-1:10 pm
Nonstop3h 35m
Lambert-St Louis
Mon 12/8
10:15 am-12:25 pm
Nonstop4h 10m
$325
Showing 1-10 of 60 results
Best time to book a flight from Irvine to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Irvine with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Irvine to Missouri
What is the cheapest month to book a flight from Irvine to Missouri?
Currently, June is the cheapest month in which you can book a flight from Irvine to Missouri (average of $60). Flying from Irvine to Missouri in April is currently the most expensive (average of $145). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from IR9 to MO?
Find hourly flight availability from Irvine to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 3, 2025.
One of the essential ways to save on airfare from Irvine to Missouri is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 42% on airfare.
What is the cheapest day to fly from Irvine to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Irvine to Missouri. Price data was last updated on November 24, 2024.
Travelers seeking maximum savings on their Irvine to Missouri flight should consider departing on Tuesday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Irvine to Missouri
Explore weekly flight availability from Irvine to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated November 3, 2025.
The most flights from IR9 to USMO are scheduled on a Sunday (11 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (8 on average).
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated November 3, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and American Airlines from Irvine to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Related info for your journey
Find useful and relevant information for your journey from Irvine to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Irvine to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Top 8 airlines flying from Irvine to Missouri
Discover the top 8 airlines that operate flights from Irvine to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$98 | Average$222 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$98 | Average$363 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$110 | Average$219 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$140 | Average$251 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$202 | Average$463 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$206 | Average$438 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$248 | Average$469 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$257 | Average$575 | FlexibilityNo cancel fee | On-time75% |