$76+ Cheap flights from Indianapolis (IND) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/21. Fares are subject to change and may not be available on all flights or dates of travel.
IND — STL
Apr 21 — Apr 281
Round-trip
1 adult, Economy
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Find cheap flights from Indianapolis to Missouri with Cheapflights
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Cheapest flights from Indianapolis to MissouriExplore the most affordable flight options available from Indianapolis to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 22, 2026.
Explore the most affordable flight options available from Indianapolis to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 22, 2026.
This CheapOair deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:39 pm
IND
- MCI
1 stop18h 10m
Frontier
Mon 5/112:34 pm
MCI
- IND
1 stop28h 20m
Frontier
Deal found 3/21![Frontier logo]()
$151
This CheapOair deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:46 pm
IND
- STL
1 stop23h 46m
Frontier
Mon 5/48:17 pm
STL
- IND
1 stop22h 37m
Frontier
Deal found 3/20![Frontier logo]()
$171
This Frontier deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2112:07 pm
IND
- STL
1 stop12h 12m
Frontier
Fri 4/248:39 am
STL
- IND
1 stop5h 43m
Frontier
Deal found 3/19![Frontier logo]()
$180
This CheapOair deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:46 pm
IND
- STL
1 stop23h 46m
Frontier
Sun 5/38:06 pm
STL
- IND
1 stop22h 54m
Frontier
Deal found 3/20![Frontier logo]()
$191
This CheapOair deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1312:14 pm
IND
- MCI
1 stop6h 15m
Frontier
Fri 5/152:34 pm
MCI
- IND
1 stop28h 20m
Frontier
Deal found 3/22![Frontier logo]()
$192
This CheapOair deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:30 pm
IND
- STL
1 stop6h 55m
Frontier
Wed 4/154:59 pm
STL
- IND
1 stop16h 28m
Frontier
Deal found 3/21![Frontier logo]()
$192
This CheapOair deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/68:30 pm
IND
- MCI
1 stop24h 28m
Frontier
Thu 4/98:46 pm
MCI
- IND
1 stop21h 49m
Frontier
Deal found 3/21![Frontier logo]()
$212
This CheapOair deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/241:39 pm
IND
- STL
1 stop22h 40m
Frontier
Sun 4/199:55 pm
STL
- IND
1 stop14h 02m
Frontier
Deal found 3/17![Frontier logo]()
$212
This CheapOair deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/198:38 am
IND
- STL
1 stop15h 41m
Frontier
Sun 4/269:55 pm
STL
- IND
1 stop14h 02m
Frontier
Deal found 3/22![Frontier logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/58:39 pm
IND
- STL
2 stops13h 16m
Frontier
Tue 5/126:33 pm
STL
- IND
1 stop15h 50m
Frontier
Deal found 3/21![Frontier logo]()
$234
This CheapOair deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/171:52 pm
IND
- STL
1 stop8h 18m
Frontier
Sat 4/184:59 pm
STL
- IND
1 stop13h 39m
Frontier
Deal found 3/19![Frontier logo]()
$236
This CheapOair deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/288:39 pm
IND
- MCI
1 stop18h 10m
Frontier
Mon 6/12:34 pm
MCI
- IND
1 stop28h 20m
Frontier
Deal found 3/21![Frontier logo]()
$257
Best flights from Indianapolis to MissouriDiscover carefully curated flight deals from Indianapolis to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 22, 2026.
Discover carefully curated flight deals from Indianapolis to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 22, 2026.
This CheapOair deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1810:44 am
IND
- STL
1 stop13h 35m
Frontier
Wed 4/224:59 pm
STL
- IND
1 stop13h 39m
Frontier
Deal found 3/17![Frontier logo]()
$191
This Southwest deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1411:05 am
IND
- MCI
Nonstop1h 35m
Southwest
Tue 4/212:55 pm
MCI
- IND
1 stop7h 00m
Southwest
Deal found 3/17![Southwest logo]()
$277
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/142:54 pm
IND
- MCI
1 stop7h 30m
American Airlines
Tue 4/212:33 pm
MCI
- IND
1 stop5h 39m
American Airlines
Deal found 3/17![American Airlines logo]()
$277
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:13 am
IND
- STL
1 stop4h 29m
Delta
Sat 4/256:48 am
STL
- IND
1 stop5h 40m
Delta
Deal found 3/19![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:07 pm
IND
- STL
1 stop4h 04m
United Airlines
Mon 4/208:15 pm
STL
- IND
1 stop3h 39m
United Airlines
Deal found 3/17![United Airlines logo]()
$318
This CheapOair deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/198:38 am
IND
- STL
1 stop15h 41m
Frontier
Sun 4/269:55 pm
STL
- IND
1 stop14h 02m
Frontier
Deal found 3/22![Frontier logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/58:39 pm
IND
- STL
2 stops13h 16m
Frontier
Tue 5/126:33 pm
STL
- IND
1 stop15h 50m
Frontier
Deal found 3/21![Frontier logo]()
$234
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/22:40 pm
IND
- STL
Nonstop1h 00m
Southwest
Mon 4/64:55 pm
STL
- IND
1 stop4h 40m
Southwest
Deal found 3/18![Southwest logo]()
$285
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:25 pm
IND
- SGF
1 stop5h 10m
Delta
Sun 6/146:45 pm
SGF
- IND
1 stop4h 49m
Delta
Deal found 3/17![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/155:33 pm
IND
- SGF
1 stop6h 02m
American Airlines
Sun 5/175:19 am
SGF
- IND
1 stop6h 51m
American Airlines
Deal found 3/21![American Airlines logo]()
$309
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/55:15 pm
IND
- STL
2 stops5h 55m
Southwest
Tue 5/126:35 am
STL
- IND
2 stops9h 00m
Southwest
Deal found 3/21![Southwest logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/112:34 pm
IND
- STL
1 stop19h 16m
Frontier
Sun 5/38:06 pm
STL
- IND
1 stop22h 54m
Frontier
Deal found 3/21![Frontier logo]()
$272
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:13 am
IND
- STL
1 stop4h 29m
Delta
Sat 4/256:48 am
STL
- IND
1 stop5h 40m
Delta
Deal found 3/19![Delta logo]()
$318
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/309:25 pm
IND
- SGF
1 stop4h 22m
United Airlines
Mon 5/46:22 pm
SGF
- IND
1 stop4h 09m
United Airlines
Deal found 3/18![United Airlines logo]()
$359
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/32:00 pm
IND
- STL
1 stop4h 50m
Southwest
Tue 4/76:35 am
STL
- IND
2 stops9h 00m
Southwest
Deal found 3/19![Southwest logo]()
$300
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/95:10 am
IND
- SGF
1 stop5h 50m
American Airlines
Sun 6/147:39 pm
SGF
- IND
1 stop4h 16m
American Airlines
Deal found 3/22![American Airlines logo]()
$364
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/224:33 pm
IND
- SGF
1 stop6h 37m
Delta
Wed 7/296:58 pm
SGF
- IND
1 stop4h 43m
Delta
Deal found 3/22![Delta logo]()
$338
This Southwest deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1812:20 pm
IND
- STL
2 stops8h 25m
Southwest
Sun 4/195:35 pm
STL
- IND
1 stop4h 40m
Southwest
Deal found 3/17![Southwest logo]()
$311
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/53:19 pm
IND
- SGF
1 stop7h 29m
United Airlines
Sun 6/76:41 pm
SGF
- IND
1 stop5h 24m
United Airlines
Deal found 3/21![United Airlines logo]()
$378
This United Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/221:44 pm
IND
- SGF
1 stop5h 16m
United Airlines
Wed 8/266:35 pm
SGF
- IND
1 stop4h 13m
United Airlines
Deal found 3/20![United Airlines logo]()
$379
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/231:05 pm
IND
- MCI
Nonstop1h 30m
Southwest
Sun 4/266:05 pm
MCI
- IND
1 stop4h 10m
Southwest
Deal found 3/19![Southwest logo]()
$314
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/176:25 pm
IND
- SGF
1 stop5h 10m
Delta
Sun 7/196:45 pm
SGF
- IND
1 stop4h 49m
Delta
Deal found 3/19![Delta logo]()
$378
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:00 pm
IND
- MCI
1 stop6h 00m
Southwest
Mon 5/111:30 pm
MCI
- IND
Nonstop1h 25m
Southwest
Deal found 3/19![Southwest logo]()
$314
This American Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/93:48 pm
IND
- SGF
1 stop6h 14m
American Airlines
Sun 4/127:34 am
SGF
- IND
1 stop8h 19m
American Airlines
Deal found 3/18![American Airlines logo]()
$432
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1512:47 pm
IND
- SGF
1 stop5h 57m
United Airlines
Sun 5/176:00 am
SGF
- IND
1 stop6h 41m
United Airlines
Deal found 3/18![United Airlines logo]()
$394
This Southwest deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:35 pm
IND
- MCI
1 stop6h 00m
Southwest
Sun 4/2611:30 am
MCI
- IND
1 stop6h 35m
Southwest
Deal found 3/17![Southwest logo]()
$349
This Southwest deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/221:05 pm
IND
- MCI
Nonstop1h 30m
Southwest
Mon 5/251:30 pm
MCI
- IND
Nonstop1h 25m
Southwest
Deal found 3/20![Southwest logo]()
$349
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:40 am
IND
- MCI
1 stop3h 35m
Southwest
Fri 5/151:30 pm
MCI
- IND
Nonstop1h 25m
Southwest
Deal found 3/22![Southwest logo]()
$349
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/111:45 pm
IND
- MCI
Nonstop1h 30m
Southwest
Sun 6/146:30 am
MCI
- IND
1 stop4h 55m
Southwest
Deal found 3/19![Southwest logo]()
$349
Last-minute flights from Indianapolis to MissouriDiscover last-minute flight deals from Indianapolis to Missouri. Data last updated March 22, 2026 and is based on user searches.
Discover last-minute flight deals from Indianapolis to Missouri. Data last updated March 22, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/241:39 pm
IND
- STL
1 stop22h 40m
Frontier
Sun 4/199:55 pm
STL
- IND
1 stop14h 02m
Frontier
Deal found 3/17![Frontier logo]()
$212
This CheapOair deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/68:30 pm
IND
- MCI
1 stop24h 28m
Frontier
Thu 4/98:46 pm
MCI
- IND
1 stop21h 49m
Frontier
Deal found 3/21![Frontier logo]()
$212
This CheapOair deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:30 pm
IND
- STL
1 stop6h 55m
Frontier
Wed 4/154:59 pm
STL
- IND
1 stop16h 28m
Frontier
Deal found 3/21![Frontier logo]()
$192
This Southwest deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1411:05 am
IND
- MCI
Nonstop1h 35m
Southwest
Tue 4/212:10 pm
MCI
- IND
Nonstop1h 25m
Southwest
Deal found 3/17![Southwest logo]()
$267
This CheapOair deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:46 pm
IND
- STL
1 stop23h 46m
Frontier
Sun 4/199:55 pm
STL
- IND
1 stop14h 02m
Frontier
Deal found 3/17![Frontier logo]()
$191
This CheapOair deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/171:52 pm
IND
- STL
1 stop8h 18m
Frontier
Sat 4/184:59 pm
STL
- IND
1 stop13h 39m
Frontier
Deal found 3/19![Frontier logo]()
$236
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1712:34 pm
IND
- MCI
2 stops26h 32m
Multiple Airlines
Wed 4/226:01 pm
MCI
- IND
1 stop12h 37m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$262
This CheapOair deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/198:38 am
IND
- STL
1 stop15h 41m
Frontier
Sun 4/269:55 pm
STL
- IND
1 stop14h 02m
Frontier
Deal found 3/22![Frontier logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:40 pm
IND
- STL
2 stops37h 10m
Multiple Airlines
Sat 4/258:23 pm
STL
- IND
1 stop13h 54m
Multiple Airlines
Deal found 3/19![Multiple Airlines logo]()
$263
This Frontier deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2112:07 pm
IND
- STL
1 stop12h 12m
Frontier
Fri 4/248:39 am
STL
- IND
1 stop5h 43m
Frontier
Deal found 3/19![Frontier logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2112:07 pm
IND
- STL
2 stops19h 43m
Frontier
Sat 4/258:23 pm
STL
- IND
1 stop13h 54m
Frontier
Deal found 3/19![Frontier logo]()
$270
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:33 pm
IND
- STL
1 stop7h 13m
American Airlines
Sat 4/255:51 am
STL
- IND
1 stop3h 28m
American Airlines
Deal found 3/19![American Airlines logo]()
$269
One-way flights from Indianapolis to MissouriSearch for one-way flight options from Indianapolis to Missouri. Find affordable one-way fares based on user searches. Data last updated March 22, 2026.
Search for one-way flight options from Indianapolis to Missouri. Find affordable one-way fares based on user searches. Data last updated March 22, 2026.
This Frontier deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2112:07 pm
IND
- STL
1 stop12h 12m
Frontier
Deal found 3/20![Frontier logo]()
$76
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1812:14 pm
IND
- MCI
1 stop6h 15m
Frontier
Deal found 3/19![Frontier logo]()
$81
This CheapOair deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/198:39 pm
IND
- MCI
1 stop18h 10m
Frontier
Deal found 3/20![Frontier logo]()
$82
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1912:12 pm
IND
- STL
1 stop19h 38m
Frontier
Deal found 3/21![Frontier logo]()
$82
This Frontier deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/171:52 pm
IND
- STL
1 stop8h 18m
Frontier
Deal found 3/20![Frontier logo]()
$90
This Frontier deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1512:07 pm
IND
- STL
1 stop12h 12m
Frontier
Deal found 3/18![Frontier logo]()
$96
This Frontier deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/211:46 pm
IND
- STL
1 stop11h 35m
Frontier
Deal found 3/22![Frontier logo]()
$101
This CheapOair deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:46 pm
IND
- MCI
1 stop18h 20m
Frontier
Deal found 3/18![Frontier logo]()
$102
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1312:14 pm
IND
- STL
1 stop29h 40m
Frontier
Deal found 3/17![Frontier logo]()
$110
This Frontier deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2012:14 pm
IND
- MCI
1 stop6h 15m
Frontier
Deal found 3/20![Frontier logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1812:14 pm
IND
- STL
2 stops13h 07m
Frontier
Deal found 3/22![Frontier logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:08 pm
IND
- STL
2 stops14h 42m
Multiple Airlines
Deal found 3/18![Multiple Airlines logo]()
$112
Find flight deals from Indianapolis to Missouri
Keep the following information in mind while searching for Indianapolis to Missouri flight deals. Data was last updated March 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $151 (CheapOair) |
One-way from | $76 (Frontier) |
Popular in | September |
Cheapest in | November |
Average price | $282 |
Good round-trip deal | $366 or less |
Good one-way deal | $183 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Indianapolis to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
Use the filters below to find and compare flights from Indianapolis to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
IndianapolisSt. Louis
IND - STL
INDSTL
Indianapolis
Sat 4/18
10:44 am-11:19 pm
1 stop13h 35m
Lambert-St Louis
Wed 4/22
4:59 pm-7:38 am
1 stop13h 39m
$191
IndianapolisSt. Louis
IND - STL
INDSTL
Indianapolis
Sun 4/19
8:38 am-11:19 pm
1 stop15h 41m
Lambert-St Louis
Sun 4/26
9:55 pm-12:57 pm
1 stop14h 02m
$216
IndianapolisSt. Louis
IND - STL
INDSTL
Indianapolis
Tue 5/5
8:39 pm-8:55 am
2 stops13h 16m
Lambert-St Louis
Tue 5/12
6:33 pm-11:23 am
1 stop15h 50m
$234
IndianapolisSt. Louis
IND - STL
INDSTL
Indianapolis
Fri 5/1
12:34 pm-6:50 am
1 stop19h 16m
Lambert-St Louis
Sun 5/3
8:06 pm-8:00 pm
1 stop22h 54m
$272
IndianapolisKansas City
IND - MCI
INDMCI
Indianapolis
Tue 4/14
11:05 am-11:40 am
Nonstop1h 35m
Kansas City
Tue 4/21
2:55 pm-10:55 pm
1 stop7h 00m
$277
IndianapolisKansas City
IND - MCI
INDMCI
Indianapolis
Tue 4/14
2:54 pm-9:24 pm
1 stop7h 30m
Kansas City
Tue 4/21
2:33 pm-9:12 pm
1 stop5h 39m
$277
IndianapolisSt. Louis
IND - STL
INDSTL
Indianapolis
Thu 4/2
2:40 pm-2:40 pm
Nonstop1h 00m
Lambert-St Louis
Mon 4/6
4:55 pm-10:35 pm
1 stop4h 40m
$285
IndianapolisSt. Louis
IND - STL
INDSTL
Indianapolis
Tue 5/5
5:15 pm-10:10 pm
2 stops5h 55m
Lambert-St Louis
Tue 5/12
6:35 am-4:35 pm
2 stops9h 00m
$285
IndianapolisSt. Louis
IND - STL
INDSTL
Indianapolis
Tue 4/21
6:13 am-9:42 am
1 stop4h 29m
Lambert-St Louis
Sat 4/25
6:48 am-1:28 pm
1 stop5h 40m
$289
IndianapolisSt. Louis
IND - STL
INDSTL
Indianapolis
Fri 4/3
2:00 pm-5:50 pm
1 stop4h 50m
Lambert-St Louis
Tue 4/7
6:35 am-4:35 pm
2 stops9h 00m
$300
Showing 1-10 of 50 resultsSorted by cheapest first
Best time to book a flight from Indianapolis to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Indianapolis with our price prediction graph.
IND-STL
IND-MCI
IND-SGF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Indianapolis to Missouri
IND-USMO
IND-STL
IND-MCI
IND-SGF
What is the cheapest month to book a flight from Indianapolis to Missouri?
Currently, September is the cheapest month in which you can book a flight from Indianapolis to Missouri (average of $75). Flying from Indianapolis to Missouri in February is currently the most expensive (average of $259). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from IND to MO?
Find hourly flight availability from Indianapolis to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 22, 2026.
Unlike in the evening, when flights are generally more expensive, you can save up to 79% on flights from Indianapolis to Missouri by exploring options for tickets at noon.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated March 22, 2026.
Read through reviews of airlines operating flights from Indianapolis to Missouri, such as Southwest,United Airlines, andAmerican Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Comfort
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Comfort
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Comfort
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Comfort
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Indianapolis to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Indianapolis to Missouri
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Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Indianapolis to Missouri by cabin class
Find flights from Indianapolis to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Indianapolis and Missouri flights
Browse other Indianapolis and Missouri flight options. Last updated on March 22, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Indianapolis to Missouri flights
Consider these flights traveling from Indianapolis to Missouri.
Top 3 airlines flying from Indianapolis to Missouri
Discover the top 3 airlines that operate flights from Indianapolis to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$178 | Average$391 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$221 | Average$327 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$228 | Average$327 | FlexibilityNo cancel fee | On-time69% |