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$64+ Cheap flights from Indianapolis (IND) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/5. Fares are subject to change and may not be available on all flights or dates of travel.
IND — STL
Nov 30 — Dec 71
Sun 11/30
Sun 12/7
1 adult, Economy
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Cheap flight deals from Indianapolis to Missouri

Keep the following information in mind while searching for Indianapolis to Missouri flight deals. Data was last updated October 31, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$222
(Kiwi.com)

One-way from

$64
(Mytrip)

Popular in

July

Cheapest in

November

Average price

$326

Good round-trip deal

$311 or less

Good one-way deal

$177 or less
Provider with most accurate pricing for Indianapolis-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Indianapolis-Lambert-St Louis flights.
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From Indianapolis to Missouri
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One-way flight from Indianapolis to Missouri
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Highest demand for flights based on searches. 1% potential increase in price ($6 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Price to beat on a round-trip flight from Indianapolis to Missouri.
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Price to beat on a one-way flight from Indianapolis to Missouri.
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Find flight deals from Indianapolis to Missouri

Cheapest flights from Indianapolis to Missouri
Explore the most affordable flight options available from Indianapolis to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 31, 2025.

This Booking.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/78:39 pmIND - MCI
1 stop23h 54mFrontier
Sun 11/93:04 pmMCI - IND
1 stop26h 40mFrontier
Deal found 10/28$208
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/148:59 pmIND - STL
1 stop19h 39mMultiple Airlines
Tue 11/187:45 pmSTL - IND
2 stops23h 19mMultiple Airlines
Deal found 10/29$222
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/279:03 amIND - STL
1 stop15h 54mMultiple Airlines
Thu 12/412:04 pmSTL - IND
1 stop26h 06mMultiple Airlines
Deal found 10/30$227
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/511:31 amIND - MCI
1 stop12h 44mMultiple Airlines
Mon 12/812:46 pmMCI - IND
1 stop5h 04mMultiple Airlines
Deal found 10/29$230
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/145:26 amIND - SGF
1 stop5h 32mAmerican Airlines
Tue 11/185:35 pmSGF - IND
1 stop4h 51mAmerican Airlines
Deal found 10/27$234
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/47:45 pmIND - MCI
1 stop5h 18mAmerican Airlines
Sun 12/76:40 amMCI - IND
1 stop5h 33mAmerican Airlines
Deal found 10/30$237
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/173:34 pmIND - STL
2 stops18h 33mFrontier
Thu 11/204:13 pmSTL - IND
1 stop15h 34mFrontier
Deal found 10/30$237
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/277:26 pmIND - STL
2 stops20h 42mFrontier
Thu 12/412:04 pmSTL - IND
1 stop26h 06mFrontier
Deal found 10/30$242
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/198:59 pmIND - MCI
1 stop16h 04mSpirit Airlines
Wed 11/266:00 amMCI - IND
1 stop25h 08mSpirit Airlines
Deal found 10/29$243
This Mytrip deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/148:59 pmIND - MCI
1 stop16h 29mSpirit Airlines
Tue 11/186:00 amMCI - IND
1 stop13h 04mSpirit Airlines
Deal found 10/30$246
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/37:00 amIND - MCI
1 stop12h 36mMultiple Airlines
Thu 12/48:09 pmMCI - IND
2 stops13h 27mMultiple Airlines
Deal found 10/29$256
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/85:34 pmIND - STL
1 stop7h 08mDelta
Tue 12/912:49 pmSTL - IND
1 stop5h 11mDelta
Deal found 10/30$257

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indianapolis to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 31, 2025.
Use the filters below to find and compare flights from Indianapolis to Missouri that are best for you.

Fly from

Indianapolis

Fly to

Missouri

Route

Depart

Return

Price

IndianapolisSt. Louis

IND - STL

INDSTL

Indianapolis

Fri 11/14

8:59 pm-3:38 pm

1 stop19h 39m

Lambert-St Louis

Tue 11/18

7:45 pm-8:04 pm

2 stops23h 19m

$222

IndianapolisSpringfield

IND - SGF

INDSGF

Indianapolis

Fri 11/14

5:26 am-9:58 am

1 stop5h 32m

Springfield-Branson

Tue 11/18

5:35 pm-11:26 pm

1 stop4h 51m

$234

IndianapolisKansas City

IND - MCI

INDMCI

Indianapolis

Sat 12/13

6:45 am-10:00 am

1 stop4h 15m

Kansas City

Mon 12/15

5:45 pm-12:12 am

1 stop5h 27m

$237

IndianapolisKansas City

IND - MCI

INDMCI

Indianapolis

Wed 12/3

4:46 pm-9:13 pm

1 stop5h 27m

Kansas City

Thu 12/4

6:40 am-12:07 pm

1 stop4h 27m

$237

IndianapolisKansas City

IND - MCI

INDMCI

Indianapolis

Tue 3/10

12:05 pm-5:22 pm

1 stop6h 17m

Kansas City

Wed 3/11

6:00 am-1:32 pm

1 stop6h 32m

$237

IndianapolisSt. Louis

IND - STL

INDSTL

Indianapolis

Mon 12/8

5:34 pm-11:42 pm

1 stop7h 08m

Lambert-St Louis

Tue 12/9

12:49 pm-7:00 pm

1 stop5h 11m

$257

IndianapolisSt. Louis

IND - STL

INDSTL

Indianapolis

Sun 12/7

5:30 am-10:33 pm

1 stop18h 03m

Lambert-St Louis

Mon 12/8

10:47 am-6:50 pm

1 stop7h 03m

$258

IndianapolisSpringfield

IND - SGF

INDSGF

Indianapolis

Thu 11/13

6:00 am-10:51 am

1 stop5h 51m

Springfield-Branson

Mon 11/17

6:35 pm-11:18 pm

1 stop3h 43m

$259

IndianapolisSt. Louis

IND - STL

INDSTL

Indianapolis

Mon 12/8

6:20 pm-10:00 pm

1 stop4h 40m

Lambert-St Louis

Tue 12/9

1:20 pm-10:35 pm

2 stops8h 15m

$262

IndianapolisKansas City

IND - MCI

INDMCI

Indianapolis

Wed 11/19

5:05 am-12:03 pm

2 stops31h 58m

Kansas City

Wed 11/26

6:00 am-10:39 pm

1 stop15h 39m

$273

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 58 results
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Best time to book a flight from Indianapolis to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Indianapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to Missouri

What is the cheapest month to book a flight from Indianapolis to Missouri?

Currently, September is the cheapest month in which you can book a flight from Indianapolis to Missouri (average of $75). Flying from Indianapolis to Missouri in January is currently the most expensive (average of $229). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IND to MO?

Find hourly flight availability from Indianapolis to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 31, 2025.

Unlike in the evening, when flights are generally more expensive, you can save up to 40% on flights from Indianapolis to Missouri by exploring options for tickets in the morning.

What is the cheapest day to fly from Indianapolis to Missouri?

Use this chart to determine the cheapest time to fly round-trip from Indianapolis to Missouri. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Indianapolis to Missouri flight should consider departing on Tuesday afternoons when fares are most often at their lowest. Saturday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated October 31, 2025.
Read through reviews of airlines operating flights from Indianapolis to Missouri, such as Southwest, Delta, and United Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,243 reviews

Crew

8.6

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,243 reviews
Southwest
8.0
Very good
4,243 reviews

Crew

8.6

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
7,998 reviews
Southwest
8.0
Very good
4,243 reviews

Crew

8.6

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
8,998 reviews
Southwest
8.0
Very good
4,243 reviews

Crew

8.6

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,035 reviews
Southwest
8.0
Very good
4,243 reviews

Crew

8.6

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Indianapolis to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Indianapolis to Missouri?

    Most people fly from Indianapolis (IND) if they book a flight from Indianapolis to Missouri. Indianapolis is conveniently located just 8.3 mi from Indianapolis’s city center.

  • How long is the flight from Indianapolis to Missouri?

    For as low as $237, American Airlines can have you in Missouri from Indianapolis in 4h 15m. There are 449 mi between Indianapolis and Missouri. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Indianapolis to Missouri one-way?

    For one-way options, check prices for Delta. According to our data, you can fly for as low as $119. Users have also found prices from $119 and $147 on United Airlines and Frontier, respectively.

  • What are the most popular routes from Indianapolis to Missouri?

    Most travelers choose Indianapolis - Kansas City, Indianapolis - Springfield-Branson or Indianapolis - Lambert-St Louis when deciding on the best route from Indianapolis to Missouri.

  • Can I find deals for flights from Indianapolis to Missouri that include hotel bookings?

    Yes. In addition to deals on Indianapolis to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indianapolis to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to Missouri.

  • Can I find deals for business class flights from Indianapolis to Missouri?

    Yes. Cheapflights offers flight deals from Indianapolis to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indianapolis to Missouri?

    Currently, September is the cheapest month in which you can book a flight from Indianapolis to Missouri (average of $75). Flying from Indianapolis to Missouri in January is currently the most expensive (average of $229). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Indianapolis to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Indianapolis to Missouri

Discover the top 4 airlines that operate flights from Indianapolis to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$178Average$337FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$221Average$334FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$228Average$419FlexibilityNo cancel feeOn-time69%
DeltaCheapest$239Average$469FlexibilityNo cancel feeOn-timeN/A

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