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$75+ Cheap flights from Indianapolis (IND) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/5. Fares are subject to change and may not be available on all flights or dates of travel.
IND — STL
Jan 3 — Jan 101
Sat 1/3
Sat 1/10
1 adult, Economy
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Cheap flight deals from Indianapolis to Missouri

Cheapest flights from Indianapolis to Missouri
Explore the most affordable flight options available from Indianapolis to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

This American Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/309:44 amIND - STL
1 stop4h 39mAmerican Airlines
Tue 1/68:13 amSTL - IND
1 stop7h 04mAmerican Airlines
Deal found 12/2$248
This Kiwi.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:39 pmIND - STL
2 stops28h 54mMultiple Airlines
Tue 1/65:11 pmSTL - IND
1 stop28h 32mMultiple Airlines
Deal found 12/2$257
This American Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/174:40 pmIND - SGF
1 stop5h 14mAmerican Airlines
Sun 12/217:03 amSGF - IND
1 stop5h 34mAmerican Airlines
Deal found 12/2$259
This Frontier deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/811:19 amIND - STL
1 stop12h 14mFrontier
Mon 12/1510:47 amSTL - IND
1 stop7h 03mFrontier
Deal found 12/3$263
This Mytrip deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/612:22 pmIND - STL
1 stop21h 37mFrontier
Mon 12/810:47 amSTL - IND
1 stop7h 03mFrontier
Deal found 12/2$273
This Booking.com deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/205:05 pmIND - STL
1 stop6h 28mFrontier
Wed 12/244:27 pmSTL - IND
1 stop22h 54mFrontier
Deal found 12/3$296
This Delta deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/82:19 pmIND - SGF
1 stop4h 50mDelta
Sat 12/134:08 pmSGF - IND
1 stop7h 04mDelta
Deal found 12/4$309
This Kiwi.com deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/118:48 amIND - STL
2 stops14h 45mMultiple Airlines
Sun 12/149:54 amSTL - IND
1 stop23h 29mMultiple Airlines
Deal found 12/3$311
This Delta deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/296:35 amIND - MCI
1 stop4h 09mDelta
Sat 1/36:00 amMCI - IND
1 stop5h 09mDelta
Deal found 12/3$315
This Kiwi.com deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/131:07 pmIND - MCI
1 stop27h 38mMultiple Airlines
Fri 12/196:15 pmMCI - IND
1 stop16h 18mMultiple Airlines
Deal found 12/3$317
This Kiwi.com deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/118:48 amIND - STL
2 stops14h 45mMultiple Airlines
Sat 12/133:30 pmSTL - IND
1 stop17h 23mMultiple Airlines
Deal found 12/4$317
This Delta deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/196:42 pmIND - SGF
1 stop4h 33mDelta
Sun 12/215:03 pmSGF - IND
1 stop6h 09mDelta
Deal found 12/2$319

Find flight deals from Indianapolis to Missouri

Keep the following information in mind while searching for Indianapolis to Missouri flight deals. Data was last updated December 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$123
(Kiwi.com)

One-way from

$75
(Kiwi.com)

Popular in

September

Cheapest in

November

Average price

$388

Good round-trip deal

$305 or less

Good one-way deal

$201 or less
Provider with most accurate pricing for Indianapolis-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Indianapolis-Lambert-St Louis flights.
Search Deals
From Indianapolis to Missouri
Search Deals
One-way flight from Indianapolis to Missouri
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($14 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from Indianapolis to Missouri.
Search Deals
Price to beat on a one-way flight from Indianapolis to Missouri.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indianapolis to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from Indianapolis to Missouri that are best for you.

Fly from

Indianapolis

Fly to

Missouri

Route

Depart

Return

Price

IndianapolisSt. Louis

IND - STL

INDSTL

Indianapolis

Mon 1/26

7:33 pm-11:33 pm

1 stop29h 00m

Lambert-St Louis

Sat 1/31

3:46 pm-3:35 pm

1 stop22h 49m

$123

IndianapolisKansas City

IND - MCI

INDMCI

Indianapolis

Sun 1/25

4:30 pm-7:51 pm

1 stop28h 21m

Kansas City

Mon 2/2

11:26 am-10:48 pm

1 stop10h 22m

$165

IndianapolisSt. Louis

IND - STL

INDSTL

Indianapolis

Mon 1/26

8:26 pm-11:33 pm

2 stops28h 07m

Lambert-St Louis

Sat 1/31

3:46 pm-3:35 pm

1 stop22h 49m

$166

IndianapolisKansas City

IND - MCI

INDMCI

Indianapolis

Mon 1/26

5:54 pm-9:03 pm

1 stop4h 09m

Kansas City

Tue 1/27

2:12 pm-9:16 pm

1 stop6h 04m

$169

IndianapolisKansas City

IND - MCI

INDMCI

Indianapolis

Mon 1/26

5:54 pm-9:03 pm

1 stop4h 09m

Kansas City

Wed 1/28

4:04 pm-11:06 pm

1 stop6h 02m

$169

IndianapolisSt. Louis

IND - STL

INDSTL

Indianapolis

Sat 3/7

10:36 am-10:33 pm

1 stop12h 57m

Lambert-St Louis

Mon 3/9

7:43 pm-7:53 pm

1 stop23h 10m

$174

IndianapolisSt. Louis

IND - STL

INDSTL

Indianapolis

Tue 1/6

12:23 pm-2:50 pm

1 stop3h 27m

Lambert-St Louis

Thu 1/8

8:13 am-4:17 pm

1 stop7h 04m

$177

IndianapolisKansas City

IND - MCI

INDMCI

Indianapolis

Mon 1/12

2:47 pm-9:03 pm

1 stop7h 16m

Kansas City

Mon 1/19

5:47 pm-12:07 am

1 stop5h 20m

$181

IndianapolisSt. Louis

IND - STL

INDSTL

Indianapolis

Thu 1/8

8:55 pm-10:02 am

1 stop14h 07m

Lambert-St Louis

Sat 1/10

5:11 pm-9:43 am

1 stop15h 32m

$184

IndianapolisSt. Louis

IND - STL

INDSTL

Indianapolis

Mon 2/2

6:55 pm-11:37 pm

1 stop5h 42m

Lambert-St Louis

Thu 2/5

7:10 am-12:46 pm

1 stop4h 36m

$195

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/3

Showing 1-10 of 52 results
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Best time to book a flight from Indianapolis to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Indianapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to Missouri

What is the cheapest month to book a flight from Indianapolis to Missouri?

Currently, September is the cheapest month in which you can book a flight from Indianapolis to Missouri (average of $75). Flying from Indianapolis to Missouri in January is currently the most expensive (average of $244). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IND to MO?

Find hourly flight availability from Indianapolis to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 4, 2025.

Unlike in the evening, when flights are generally more expensive, you can save up to 40% on flights from Indianapolis to Missouri by exploring options for tickets in the morning.

What is the cheapest day to fly from Indianapolis to Missouri?

Use this chart to determine the cheapest time to fly round-trip from Indianapolis to Missouri. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Indianapolis to Missouri flight should consider departing on Tuesday afternoons when fares are most often at their lowest. Saturday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated December 4, 2025.
Read through reviews of airlines operating flights from Indianapolis to Missouri, such as Southwest, United Airlines, and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,250 reviews

Crew

8.6

Boarding

8.1

Food

7.0

Comfort

8.0

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,250 reviews
Southwest
8.0
Very good
4,250 reviews

Crew

8.6

Boarding

8.1

Food

7.0

Comfort

8.0

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,066 reviews
Southwest
8.0
Very good
4,250 reviews

Crew

8.6

Boarding

8.1

Food

7.0

Comfort

8.0

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,047 reviews
Southwest
8.0
Very good
4,250 reviews

Crew

8.6

Boarding

8.1

Food

7.0

Comfort

8.0

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Indianapolis to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Indianapolis to Missouri?

    Most people fly from Indianapolis (IND) if they book a flight from Indianapolis to Missouri. Indianapolis is conveniently located just 8.3 mi from Indianapolis’s city center.

  • How long is the flight from Indianapolis to Missouri?

    For as low as $177, Frontier can have you in Missouri from Indianapolis in 3h 27m. There are 228 mi between Indianapolis and Missouri. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Indianapolis to Missouri one-way?

    For one-way options, check prices for United Airlines. According to our data, you can fly for as low as $94. Users have also found prices from $98 and $122 on American Airlines and Southwest, respectively.

  • What are the most popular routes from Indianapolis to Missouri?

    Most travelers choose Indianapolis - Kansas City, Indianapolis - Lambert-St Louis or Indianapolis - Springfield-Branson when deciding on the best route from Indianapolis to Missouri.

  • Can I find deals for flights from Indianapolis to Missouri that include hotel bookings?

    Yes. In addition to deals on Indianapolis to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indianapolis to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to Missouri.

  • Can I find deals for business class flights from Indianapolis to Missouri?

    Yes. Cheapflights offers flight deals from Indianapolis to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indianapolis to Missouri?

    Currently, September is the cheapest month in which you can book a flight from Indianapolis to Missouri (average of $75). Flying from Indianapolis to Missouri in January is currently the most expensive (average of $244). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Indianapolis to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Indianapolis to Missouri

Discover the top 3 airlines that operate flights from Indianapolis to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$178Average$364FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$221Average$325FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$228Average$411FlexibilityNo cancel feeOn-time69%

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