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$68+ Cheap flights from Indianapolis (IND) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/22. Fares are subject to change and may not be available on all flights or dates of travel.
IND — STL
Feb 20 — Feb 271
Fri 2/20
Fri 2/27
1 adult, Economy
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Cheap flight deals from Indianapolis to Missouri

Cheapest flights from Indianapolis to Missouri
Explore the most affordable flight options available from Indianapolis to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/197:27 pm
IND
-
MCI
1 stop15h 36m
Frontier
Mon 2/2310:55 am
MCI
-
IND
1 stop6h 36m
Frontier
Deal found 1/19$163
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/137:41 pm
IND
-
STL
1 stop12h 10m
Multiple Airlines
Mon 2/163:49 pm
STL
-
IND
1 stop15h 43m
Multiple Airlines
Deal found 1/19$175
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/197:27 pm
IND
-
STL
1 stop12h 24m
Frontier
Thu 2/2610:11 pm
STL
-
IND
2 stops20h 36m
Frontier
Deal found 1/20$180
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/188:18 pm
IND
-
MCI
1 stop15h 12m
Multiple Airlines
Mon 2/2310:55 am
MCI
-
IND
1 stop6h 36m
Multiple Airlines
Deal found 1/19$184
This Kiwi.com deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/166:10 pm
IND
-
MCI
1 stop22h 19m
Multiple Airlines
Mon 2/2310:55 am
MCI
-
IND
1 stop6h 36m
Multiple Airlines
Deal found 1/18$185
This Kiwi.com deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/188:18 pm
IND
-
MCI
1 stop15h 12m
Multiple Airlines
Wed 2/254:39 pm
MCI
-
IND
1 stop26h 18m
Multiple Airlines
Deal found 1/21$195
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/197:27 pm
IND
-
MCI
2 stops16h 03m
Multiple Airlines
Mon 2/2310:55 am
MCI
-
IND
1 stop6h 36m
Multiple Airlines
Deal found 1/19$201
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/107:15 am
IND
-
MCI
1 stop4h 17m
United Airlines
Tue 2/103:24 pm
MCI
-
IND
1 stop5h 50m
United Airlines
Deal found 1/20$211
This Kiwi.com deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/61:44 pm
IND
-
STL
1 stop26h 02m
Multiple Airlines
Sun 2/85:42 pm
STL
-
IND
1 stop15h 01m
Multiple Airlines
Deal found 1/21$221
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1712:54 pm
IND
-
MCI
1 stop5h 06m
Delta
Fri 3/205:40 pm
MCI
-
IND
1 stop5h 07m
Delta
Deal found 1/21$225
This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/146:12 am
IND
-
MCI
1 stop8h 13m
American Airlines
Tue 2/171:18 pm
MCI
-
IND
1 stop4h 52m
American Airlines
Deal found 1/21$231
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/197:27 pm
IND
-
STL
1 stop12h 24m
Multiple Airlines
Thu 2/2610:11 pm
STL
-
IND
1 stop18h 36m
Multiple Airlines
Deal found 1/20$231

Find flight deals from Indianapolis to Missouri

Keep the following information in mind while searching for Indianapolis to Missouri flight deals. Data was last updated January 21, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$163
(Kiwi.com)

One-way from

$68
(Kiwi.com)

Popular in

September

Cheapest in

November

Average price

$386

Good round-trip deal

$438 or less

Good one-way deal

$233 or less
Provider with most accurate pricing for Indianapolis-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Indianapolis-Lambert-St Louis flights.
Search Deals
From Indianapolis to Missouri
Search Deals
One-way flight from Indianapolis to Missouri
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($35 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals
Price to beat on a round-trip flight from Indianapolis to Missouri.
Search Deals
Price to beat on a one-way flight from Indianapolis to Missouri.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indianapolis to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from Indianapolis to Missouri that are best for you.

Fly from

Indianapolis

Fly to

Missouri

Route

Depart

Return

Price

IndianapolisSt. Louis

IND - STL

INDSTL

Indianapolis

Thu 2/19

7:27 pm-6:51 am

1 stop12h 24m

Lambert-St Louis

Thu 2/26

10:11 pm-7:47 pm

2 stops20h 36m

$180

IndianapolisKansas City

IND - MCI

INDMCI

Indianapolis

Wed 2/18

8:18 pm-10:30 am

1 stop15h 12m

Kansas City

Mon 2/23

10:55 am-6:31 pm

1 stop6h 36m

$184

IndianapolisKansas City

IND - MCI

INDMCI

Indianapolis

Mon 2/16

6:10 pm-3:29 pm

1 stop22h 19m

Kansas City

Mon 2/23

10:55 am-6:31 pm

1 stop6h 36m

$185

IndianapolisKansas City

IND - MCI

INDMCI

Indianapolis

Tue 2/10

7:15 am-10:32 am

1 stop4h 17m

Kansas City

Tue 2/10

3:24 pm-10:14 pm

1 stop5h 50m

$211

IndianapolisSt. Louis

IND - STL

INDSTL

Indianapolis

Fri 2/6

1:44 pm-2:46 pm

1 stop26h 02m

Lambert-St Louis

Sun 2/8

5:42 pm-9:43 am

1 stop15h 01m

$221

IndianapolisKansas City

IND - MCI

INDMCI

Indianapolis

Tue 3/17

12:54 pm-5:00 pm

1 stop5h 06m

Kansas City

Fri 3/20

5:40 pm-11:47 pm

1 stop5h 07m

$225

IndianapolisSt. Louis

IND - STL

INDSTL

Indianapolis

Thu 2/19

7:27 pm-6:51 am

1 stop12h 24m

Lambert-St Louis

Thu 2/26

10:11 pm-5:47 pm

1 stop18h 36m

$231

IndianapolisKansas City

IND - MCI

INDMCI

Indianapolis

Thu 2/19

6:10 pm-9:59 pm

1 stop4h 49m

Kansas City

Sun 2/22

9:10 am-4:49 pm

1 stop6h 39m

$237

IndianapolisKansas City

IND - MCI

INDMCI

Indianapolis

Sun 2/22

3:40 pm-9:07 pm

1 stop6h 27m

Kansas City

Mon 2/23

5:47 pm-12:07 am

1 stop5h 20m

$239

IndianapolisKansas City

IND - MCI

INDMCI

Indianapolis

Sat 3/28

12:54 pm-4:59 pm

1 stop5h 05m

Kansas City

Tue 3/31

2:15 pm-9:10 pm

1 stop5h 55m

$239

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/21

Showing 1-10 of 52 results
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Best time to book a flight from Indianapolis to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Indianapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to Missouri

What is the cheapest month to book a flight from Indianapolis to Missouri?

Currently, September is the cheapest month in which you can book a flight from Indianapolis to Missouri (average of $75). Flying from Indianapolis to Missouri in December is currently the most expensive (average of $259). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IND to MO?

Find hourly flight availability from Indianapolis to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 21, 2026.

Unlike in the evening, when flights are generally more expensive, you can save up to 79% on flights from Indianapolis to Missouri by exploring options for tickets in the morning.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated January 21, 2026.
Read through reviews of airlines operating flights from Indianapolis to Missouri, such as Southwest, United Airlines, and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,266 reviews

Boarding

8.1

Crew

8.6

Overall

8.0

Entertainment

7.5

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,266 reviews
Southwest
8.0
Very good
4,266 reviews

Boarding

8.1

Crew

8.6

Overall

8.0

Entertainment

7.5

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,191 reviews
Southwest
8.0
Very good
4,266 reviews

Boarding

8.1

Crew

8.6

Overall

8.0

Entertainment

7.5

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,174 reviews
Southwest
8.0
Very good
4,266 reviews

Boarding

8.1

Crew

8.6

Overall

8.0

Entertainment

7.5

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Indianapolis to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Indianapolis to Missouri?

    Most people fly from Indianapolis (IND) if they book a flight from Indianapolis to Missouri. Indianapolis is conveniently located just 8.3 mi from Indianapolis’s city center.

  • How long is the flight from Indianapolis to Missouri?

    For as low as $211, Frontier can have you in Missouri from Indianapolis in 4h 17m. There are 449 mi between Indianapolis and Missouri. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Indianapolis to Missouri one-way?

    For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $98. Users have also found prices from $118 and $129 on Southwest and United Airlines, respectively.

  • What are the most popular routes from Indianapolis to Missouri?

    Most travelers choose Indianapolis - Kansas City, Indianapolis - Lambert-St Louis or Indianapolis - Springfield-Branson when deciding on the best route from Indianapolis to Missouri.

  • Can I find deals for flights from Indianapolis to Missouri that include hotel bookings?

    Yes. In addition to deals on Indianapolis to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indianapolis to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to Missouri.

  • Can I find deals for business class flights from Indianapolis to Missouri?

    Yes. Cheapflights offers flight deals from Indianapolis to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indianapolis to Missouri?

    Currently, September is the cheapest month in which you can book a flight from Indianapolis to Missouri (average of $75). Flying from Indianapolis to Missouri in December is currently the most expensive (average of $259). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Indianapolis to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Indianapolis to Missouri

Discover the top 3 airlines that operate flights from Indianapolis to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$178Average$404FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$221Average$333FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$239Average$337FlexibilityNo cancel feeOn-time69%

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