$59+ Cheap flights from Indiana to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel.
IND — STL
Apr 22 — Apr 291
Round-trip
1 adult, Economy
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Find cheap flights from Indiana to Missouri with Cheapflights
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Cheapest flights from Indiana to MissouriExplore the most affordable flight options available from Indiana to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 23, 2026.
Explore the most affordable flight options available from Indiana to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:53 pm
CVG
- STL
1 stop12h 57m
Frontier
Wed 4/228:23 pm
STL
- CVG
1 stop20h 10m
Frontier
Deal found 3/19![Frontier logo]()
$144
This CheapOair deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:39 pm
IND
- MCI
1 stop18h 10m
Frontier
Mon 5/112:34 pm
MCI
- IND
1 stop28h 20m
Frontier
Deal found 3/21![Frontier logo]()
$151
This Frontier deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/97:20 am
CVG
- MCI
1 stop13h 41m
Frontier
Fri 4/1711:19 am
MCI
- CVG
1 stop6h 17m
Frontier
Deal found 3/20![Frontier logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/47:46 pm
CVG
- STL
1 stop22h 50m
Frontier
Fri 5/85:27 pm
STL
- CVG
1 stop17h 14m
Frontier
Deal found 3/21![Frontier logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/512:12 pm
CVG
- STL
1 stop21h 43m
Frontier
Fri 5/85:27 pm
STL
- CVG
1 stop17h 14m
Frontier
Deal found 3/21![Frontier logo]()
$177
This Frontier deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:12 pm
CVG
- STL
1 stop6h 21m
Frontier
Mon 6/14:19 pm
STL
- CVG
1 stop6h 21m
Frontier
Deal found 3/20![Frontier logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1410:51 am
CVG
- STL
2 stops20h 59m
Frontier
Wed 4/158:23 pm
STL
- CVG
1 stop20h 10m
Frontier
Deal found 3/19![Frontier logo]()
$186
This CheapOair deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/68:39 pm
IND
- MCI
1 stop18h 10m
Frontier
Mon 5/112:34 pm
MCI
- IND
1 stop28h 20m
Frontier
Deal found 3/22![Frontier logo]()
$192
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:38 pm
CVG
- STL
1 stop13h 12m
Frontier
Thu 4/238:06 pm
STL
- CVG
1 stop22h 06m
Frontier
Deal found 3/19![Frontier logo]()
$194
This Priceline deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/254:26 pm
CVG
- STL
1 stop7h 53m
Frontier
Sun 4/2611:44 am
STL
- CVG
1 stop5h 04m
Frontier
Deal found 3/20![Frontier logo]()
$201
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/47:46 pm
CVG
- STL
1 stop22h 50m
Frontier
Sat 5/95:27 pm
STL
- CVG
1 stop16h 37m
Frontier
Deal found 3/21![Frontier logo]()
$202
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/512:12 pm
CVG
- STL
1 stop21h 43m
Frontier
Sat 5/95:27 pm
STL
- CVG
1 stop16h 37m
Frontier
Deal found 3/21![Frontier logo]()
$207
Best flights from Indiana to MissouriDiscover carefully curated flight deals from Indiana to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 23, 2026.
Discover carefully curated flight deals from Indiana to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 23, 2026.
This Southwest deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/35:15 am
MDW
- STL
1 stop5h 50m
Southwest
Tue 5/128:45 pm
STL
- MDW
Nonstop1h 05m
Southwest
Deal found 3/20![Southwest logo]()
$237
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2810:57 pm
ORD
- COU
Nonstop1h 33m
United Airlines
Sat 5/305:00 am
COU
- ORD
Nonstop1h 41m
United Airlines
Deal found 3/19![United Airlines logo]()
$239
This American Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/187:56 pm
ORD
- COU
Nonstop1h 34m
American Airlines
Sat 4/2510:16 am
COU
- ORD
Nonstop1h 31m
American Airlines
Deal found 3/21![American Airlines logo]()
$239
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:30 am
ORD
- SGF
1 stop5h 37m
Delta
Thu 4/163:59 pm
SGF
- ORD
1 stop5h 26m
Delta
Deal found 3/19![Delta logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:46 pm
IND
- MCI
1 stop18h 20m
Multiple Airlines
Sun 4/2611:53 am
MCI
- IND
2 stops11h 06m
Multiple Airlines
Deal found 3/18![Multiple Airlines logo]()
$290
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1010:50 pm
ORD
- COU
Nonstop1h 43m
United Airlines
Mon 4/138:00 am
COU
- ORD
Nonstop1h 30m
United Airlines
Deal found 3/19![United Airlines logo]()
$239
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/293:25 pm
MDW
- STL
1 stop5h 25m
Southwest
Tue 6/21:15 pm
STL
- MDW
2 stops6h 20m
Southwest
Deal found 3/19![Southwest logo]()
$248
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/104:40 pm
ORD
- COU
1 stop6h 13m
American Airlines
Sun 4/126:00 am
COU
- ORD
Nonstop1h 43m
American Airlines
Deal found 3/19![American Airlines logo]()
$248
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/189:15 am
ORD
- COU
Nonstop1h 40m
United Airlines
Sat 4/258:00 am
COU
- ORD
Nonstop1h 30m
United Airlines
Deal found 3/21![United Airlines logo]()
$239
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/41:24 pm
MDW
- MCI
2 stops8h 47m
Delta
Wed 5/66:30 am
MCI
- MDW
1 stop6h 13m
Delta
Deal found 3/18![Delta logo]()
$273
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/139:30 pm
MDW
- STL
Nonstop1h 15m
Southwest
Fri 4/171:45 pm
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 3/18![Southwest logo]()
$264
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:00 am
ORD
- MCI
2 stops9h 50m
Delta
Tue 5/265:13 pm
MCI
- ORD
1 stop5h 14m
Delta
Deal found 3/19![Delta logo]()
$273
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1610:45 pm
ORD
- SGF
Nonstop1h 51m
United Airlines
Sat 4/1811:23 am
SGF
- ORD
Nonstop1h 52m
United Airlines
Deal found 3/21![United Airlines logo]()
$249
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/305:00 am
ORD
- COU
1 stop6h 35m
American Airlines
Sun 5/36:00 am
COU
- ORD
Nonstop1h 43m
American Airlines
Deal found 3/19![American Airlines logo]()
$293
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/28:02 pm
ORD
- SGF
Nonstop2h 00m
United Airlines
Wed 5/66:22 pm
SGF
- ORD
Nonstop1h 43m
United Airlines
Deal found 3/19![United Airlines logo]()
$249
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/213:50 pm
CVG
- STL
1 stop6h 15m
Southwest
Sat 4/252:25 pm
STL
- CVG
1 stop5h 20m
Southwest
Deal found 3/21![Southwest logo]()
$275
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:00 am
CVG
- MCI
1 stop4h 51m
Delta
Wed 4/156:30 am
MCI
- CVG
1 stop6h 46m
Delta
Deal found 3/18![Delta logo]()
$282
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2410:45 pm
ORD
- SGF
Nonstop1h 51m
United Airlines
Wed 4/296:50 pm
SGF
- ORD
Nonstop1h 48m
United Airlines
Deal found 3/22![United Airlines logo]()
$249
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:30 am
ORD
- SGF
1 stop5h 37m
Delta
Fri 4/246:55 pm
SGF
- ORD
1 stop5h 04m
Delta
Deal found 3/22![Delta logo]()
$284
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:55 pm
MDW
- STL
1 stop5h 20m
Southwest
Mon 4/271:35 pm
STL
- MDW
1 stop5h 35m
Southwest
Deal found 3/18![Southwest logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/111:50 pm
CVG
- MCI
1 stop19h 04m
Multiple Airlines
Mon 4/136:04 pm
MCI
- CVG
2 stops20h 48m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$379
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/98:20 pm
ORD
- STL
Nonstop1h 32m
United Airlines
Mon 4/138:21 am
STL
- ORD
Nonstop1h 29m
United Airlines
Deal found 3/18![United Airlines logo]()
$253
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/15:40 pm
MDW
- MCI
1 stop5h 15m
Southwest
Thu 6/41:30 pm
MCI
- MDW
1 stop4h 25m
Southwest
Deal found 3/19![Southwest logo]()
$285
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/185:04 pm
ORD
- STL
2 stops6h 09m
Delta
Mon 4/2012:23 pm
STL
- ORD
2 stops8h 17m
Delta
Deal found 3/18![Delta logo]()
$295
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:05 am
CVG
- STL
2 stops9h 10m
Southwest
Sat 5/96:10 am
STL
- CVG
2 stops6h 50m
Southwest
Deal found 3/22![Southwest logo]()
$285
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/308:48 am
ORD
- SGF
Nonstop1h 54m
United Airlines
Wed 6/36:41 pm
SGF
- ORD
Nonstop1h 53m
United Airlines
Deal found 3/19![United Airlines logo]()
$264
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/11:36 pm
ORD
- STL
2 stops9h 37m
Delta
Mon 5/46:20 am
STL
- ORD
2 stops6h 25m
Delta
Deal found 3/19![Delta logo]()
$295
This American Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/176:30 pm
DAY
- STL
1 stop6h 26m
American Airlines
Tue 5/197:00 am
STL
- DAY
1 stop5h 22m
American Airlines
Deal found 3/18![American Airlines logo]()
$395
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/234:15 pm
ORD
- SGF
Nonstop1h 51m
United Airlines
Sun 6/287:45 am
SGF
- ORD
Nonstop1h 55m
United Airlines
Deal found 3/18![United Airlines logo]()
$264
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/81:05 pm
IND
- MCI
Nonstop1h 30m
Southwest
Mon 5/111:30 pm
MCI
- IND
Nonstop1h 25m
Southwest
Deal found 3/23![Southwest logo]()
$294
Last-minute flights from Indiana to MissouriDiscover last-minute flight deals from Indiana to Missouri. Data last updated March 23, 2026 and is based on user searches.
Discover last-minute flight deals from Indiana to Missouri. Data last updated March 23, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/68:30 pm
IND
- MCI
1 stop24h 28m
Frontier
Thu 4/98:46 pm
MCI
- IND
1 stop21h 49m
Frontier
Deal found 3/21![Frontier logo]()
$212
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/87:45 am
MDW
- MCI
Nonstop1h 30m
Southwest
Wed 4/83:30 pm
MCI
- MDW
Nonstop1h 25m
Southwest
Deal found 3/18![Southwest logo]()
$231
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/88:40 am
ORD
- MCI
Nonstop1h 47m
United Airlines
Wed 4/87:00 pm
MCI
- ORD
Nonstop1h 50m
United Airlines
Deal found 3/18![United Airlines logo]()
$231
This Frontier deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/97:20 am
CVG
- MCI
1 stop13h 41m
Frontier
Fri 4/1711:19 am
MCI
- CVG
1 stop6h 17m
Frontier
Deal found 3/20![Frontier logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1410:51 am
CVG
- STL
2 stops20h 59m
Frontier
Wed 4/158:23 pm
STL
- CVG
1 stop20h 10m
Frontier
Deal found 3/19![Frontier logo]()
$186
This Frontier deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:20 pm
CVG
- STL
1 stop6h 59m
Frontier
Thu 4/1611:25 am
STL
- CVG
1 stop5h 08m
Frontier
Deal found 3/22![Frontier logo]()
$225
This KAYAK deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1411:55 am
ORD
- STL
1 stop9h 20m
Southwest
Thu 4/165:25 am
STL
- ORD
1 stop12h 05m
Southwest
Deal found 3/18![Southwest logo]()
$234
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:38 pm
CVG
- STL
1 stop13h 12m
Frontier
Thu 4/238:06 pm
STL
- CVG
1 stop22h 06m
Frontier
Deal found 3/19![Frontier logo]()
$194
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:38 pm
CVG
- STL
1 stop13h 12m
Frontier
Sat 4/188:23 pm
STL
- CVG
1 stop20h 25m
Frontier
Deal found 3/18![Frontier logo]()
$208
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:53 pm
CVG
- STL
1 stop12h 57m
Frontier
Wed 4/228:23 pm
STL
- CVG
1 stop20h 10m
Frontier
Deal found 3/19![Frontier logo]()
$144
This Priceline deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/254:26 pm
CVG
- STL
1 stop7h 53m
Frontier
Sun 4/2611:44 am
STL
- CVG
1 stop5h 04m
Frontier
Deal found 3/20![Frontier logo]()
$201
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/305:25 pm
MDW
- MCI
Nonstop1h 30m
Southwest
Tue 5/55:25 am
MCI
- MDW
Nonstop1h 25m
Southwest
Deal found 3/22![Southwest logo]()
$234
One-way flights from Indiana to MissouriSearch for one-way flight options from Indiana to Missouri. Find affordable one-way fares based on user searches. Data last updated March 23, 2026.
Search for one-way flight options from Indiana to Missouri. Find affordable one-way fares based on user searches. Data last updated March 23, 2026.
This Southwest deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:15 am
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 3/20![Southwest logo]()
$59
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1410:25 am
ORD
- STL
Nonstop1h 22m
American Airlines
Deal found 3/20![American Airlines logo]()
$59
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/912:20 pm
CVG
- STL
1 stop6h 14m
Frontier
Deal found 3/19![Frontier logo]()
$69
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1410:30 am
ORD
- STL
1 stop7h 35m
Southwest
Deal found 3/19![Southwest logo]()
$69
This Priceline deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/184:26 pm
CVG
- STL
1 stop7h 53m
Frontier
Deal found 3/20![Frontier logo]()
$70
This Frontier deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/84:52 pm
MDW
- STL
1 stop7h 29m
Frontier
Deal found 3/22![Frontier logo]()
$70
This Frontier deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/114:21 pm
ORD
- STL
1 stop7h 04m
Frontier
Deal found 3/20![Frontier logo]()
$70
This Southwest deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/152:40 pm
ORD
- STL
1 stop7h 20m
Southwest
Deal found 3/20![Southwest logo]()
$74
This Expedia deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/105:05 pm
ORD
- STL
1 stop6h 53m
Frontier
Deal found 3/21![Frontier logo]()
$75
This Expedia deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/812:55 pm
CVG
- MCI
1 stop25h 54m
Frontier
Deal found 3/20![Frontier logo]()
$76
This Expedia deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:17 pm
CVG
- STL
1 stop24h 15m
Frontier
Deal found 3/20![Frontier logo]()
$76
This Expedia deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/89:42 pm
ORD
- STL
1 stop21h 41m
Frontier
Deal found 3/22![Frontier logo]()
$76
Find flight deals from Indiana to Missouri
Keep the following information in mind while searching for Indiana to Missouri flight deals. Data was last updated March 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $144 (Kiwi.com) |
One-way from | $59 (Southwest) |
Popular in | September |
Cheapest in | November |
Average price | $282 |
Good round-trip deal | $359 or less |
Good one-way deal | $183 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Indiana to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
Use the filters below to find and compare flights from Indiana to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Sun 5/3
5:15 am-11:05 am
1 stop5h 50m
Lambert-St Louis
Tue 5/12
8:45 pm-9:50 pm
Nonstop1h 05m
$237
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Thu 5/28
10:57 pm-12:30 am
Nonstop1h 33m
Columbia Regional
Sat 5/30
5:00 am-6:41 am
Nonstop1h 41m
$239
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Sat 4/18
7:56 pm-9:30 pm
Nonstop1h 34m
Columbia Regional
Sat 4/25
10:16 am-11:47 am
Nonstop1h 31m
$239
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Fri 4/10
10:50 pm-12:33 am
Nonstop1h 43m
Columbia Regional
Mon 4/13
8:00 am-9:30 am
Nonstop1h 30m
$239
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Sat 4/18
9:15 am-10:55 am
Nonstop1h 40m
Columbia Regional
Sat 4/25
8:00 am-9:30 am
Nonstop1h 30m
$239
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Fri 5/29
3:25 pm-8:50 pm
1 stop5h 25m
Lambert-St Louis
Tue 6/2
1:15 pm-7:35 pm
2 stops6h 20m
$248
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Fri 4/10
4:40 pm-10:53 pm
1 stop6h 13m
Columbia Regional
Sun 4/12
6:00 am-7:43 am
Nonstop1h 43m
$248
ChicagoSpringfield
ORD - SGF
ORDSGF
Chicago O'Hare Intl
Thu 4/16
10:45 pm-12:36 am
Nonstop1h 51m
Springfield-Branson
Sat 4/18
11:23 am-1:15 pm
Nonstop1h 52m
$249
ChicagoSpringfield
ORD - SGF
ORDSGF
Chicago O'Hare Intl
Sat 5/2
8:02 pm-10:02 pm
Nonstop2h 00m
Springfield-Branson
Wed 5/6
6:22 pm-8:05 pm
Nonstop1h 43m
$249
ChicagoSpringfield
ORD - SGF
ORDSGF
Chicago O'Hare Intl
Fri 4/24
10:45 pm-12:36 am
Nonstop1h 51m
Springfield-Branson
Wed 4/29
6:50 pm-8:38 pm
Nonstop1h 48m
$249
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Indiana to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Indiana with our price prediction graph.
CVG-STL
IND-MCI
CVG-MCI
MDW-MCI
ORD-MCI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Indiana to Missouri
USIN-USMO
CVG-STL
IND-MCI
CVG-MCI
MDW-MCI
What is the cheapest month to book a flight from Indiana to Missouri?
Currently, September is the cheapest month in which you can book a flight from Indiana to Missouri (average of $75). Flying from Indiana to Missouri in March is currently the most expensive (average of $239). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from IN to MO?
Find hourly flight availability from Indiana to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 23, 2026.
A simple way to save on the total cost of your ticket is to fly from Indiana to Missouri at noon. If you’re flexible enough to do this you can expect to save up to 79% on your trip compared to booking a flight in the evening.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated March 23, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Indiana to Missouri. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Overall
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Overall
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Overall
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Overall
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Overall
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Indiana to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Indiana to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Indiana to Missouri by cabin class
Find flights from Indiana to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Indiana and Missouri flights
Browse other Indiana and Missouri flight options. Last updated on March 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Indiana after your stay in Missouri
Indiana to Missouri flights
Consider these flights traveling from Indiana to Missouri.
Top 4 airlines flying from Indiana to Missouri
Discover the top 4 airlines that operate flights from Indiana to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$178 | Average$337 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$213 | Average$358 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$216 | Average$322 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$221 | Average$330 | FlexibilityNo cancel fee | On-time63% |