HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Missouri

$49+ Cheap flights from Indiana to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/14. Fares are subject to change and may not be available on all flights or dates of travel.
IND — STL
Dec 21 — Dec 281
Sun 12/21
Sun 12/28
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Indiana to Missouri with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Indiana to Missouri

Keep the following information in mind while searching for Indiana to Missouri flight deals. Data was last updated November 21, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$110
(Frontier)

One-way from

$49
(Southwest)

Popular in

September

Cheapest in

November

Average price

$256

Good round-trip deal

$311 or less

Good one-way deal

$133 or less
Provider with most accurate pricing for Indianapolis-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Indianapolis-Lambert-St Louis flights.
Search Deals
From Indiana to Missouri
Search Deals
One-way flight from Indiana to Missouri
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($14 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals
Price to beat on a round-trip flight from Indiana to Missouri.
Search Deals
Price to beat on a one-way flight from Indiana to Missouri.
Search Deals

Find flight deals from Indiana to Missouri

Cheapest flights from Indiana to Missouri
Explore the most affordable flight options available from Indiana to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 21, 2025.

This American Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:14 amORD - STL
Nonstop1h 34mAmerican Airlines
Tue 1/136:46 pmSTL - ORD
Nonstop1h 34mAmerican Airlines
Deal found 11/20$141
This Kiwi.com deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/117:23 pmMDW - STL
1 stop14h 24mFrontier
Sun 12/1410:42 amSTL - MDW
1 stop23h 10mFrontier
Deal found 11/19$147
This United Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/179:23 pmORD - STL
Nonstop1h 22mUnited Airlines
Wed 12/249:55 amSTL - ORD
Nonstop1h 35mUnited Airlines
Deal found 11/20$147
This Frontier deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/113:10 pmMDW - STL
1 stop7h 23mFrontier
Thu 1/83:43 pmSTL - MDW
1 stop6h 34mFrontier
Deal found 11/19$150
This Frontier deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/48:55 pmCVG - STL
1 stop13h 04mFrontier
Mon 12/89:54 amSTL - CVG
1 stop6h 50mFrontier
Deal found 11/19$150
This Frontier deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/49:53 pmORD - STL
1 stop13h 29mFrontier
Mon 12/812:07 pmSTL - ORD
1 stop8h 10mFrontier
Deal found 11/19$150
This Southwest deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/171:45 pmMDW - STL
1 stop5h 45mSouthwest
Wed 12/244:25 pmSTL - MDW
Nonstop1h 10mSouthwest
Deal found 11/19$157
This Delta deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/244:01 pmORD - STL
1 stop6h 15mDelta
Thu 12/256:29 amSTL - ORD
1 stop6h 25mDelta
Deal found 11/20$157
This Frontier deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/152:26 pmORD - STL
1 stop8h 07mFrontier
Thu 12/1810:42 amSTL - ORD
1 stop11h 42mFrontier
Deal found 11/18$164
This Southwest deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/206:20 amMDW - STL
Nonstop1h 15mSouthwest
Thu 11/271:05 pmSTL - MDW
Nonstop1h 10mSouthwest
Deal found 11/19$168
This Delta deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:31 pmORD - STL
1 stop6h 07mDelta
Tue 1/1312:00 pmSTL - ORD
1 stop7h 35mDelta
Deal found 11/20$178
This Frontier deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/117:19 pmIND - STL
1 stop15h 55mFrontier
Mon 12/1510:47 amSTL - IND
1 stop7h 03mFrontier
Deal found 11/19$183

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indiana to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 21, 2025.
Use the filters below to find and compare flights from Indiana to Missouri that are best for you.

Fly from

Indiana

Fly to

Missouri

Route

Depart

Return

Price

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

Thu 1/15

12:30 pm-1:45 pm

Nonstop1h 15m

Lambert-St Louis

Sun 1/18

6:05 am-7:15 am

Nonstop1h 10m

$138

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

Thu 1/1

8:25 am-9:40 am

Nonstop1h 15m

Lambert-St Louis

Mon 1/5

2:30 pm-3:40 pm

Nonstop1h 10m

$147

CincinnatiSt. Louis

CVG - STL

CVGSTL

Cincinnati Cinci./N. Kentucky

Thu 12/4

8:55 pm-8:59 am

1 stop13h 04m

Lambert-St Louis

Mon 12/8

9:54 am-5:44 pm

1 stop6h 50m

$150

CincinnatiSt. Louis

CVG - STL

CVGSTL

Cincinnati Cinci./N. Kentucky

Thu 1/8

11:57 am-10:33 pm

1 stop11h 36m

Lambert-St Louis

Mon 1/12

1:07 pm-11:59 pm

1 stop9h 52m

$150

CincinnatiKansas City

CVG - MCI

CVGMCI

Cincinnati Cinci./N. Kentucky

Fri 1/23

1:45 pm-7:46 pm

1 stop7h 01m

Kansas City

Sun 1/25

8:41 pm-8:53 pm

1 stop23h 12m

$152

IndianapolisSt. Louis

IND - STL

INDSTL

Indianapolis

Mon 1/26

7:33 pm-11:33 pm

1 stop29h 00m

Lambert-St Louis

Thu 1/29

4:45 pm-9:43 am

1 stop15h 58m

$162

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

Wed 12/17

6:20 pm-10:10 pm

1 stop3h 50m

Lambert-St Louis

Wed 12/24

12:00 pm-5:10 pm

1 stop5h 10m

$167

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

Sun 1/11

6:10 am-2:48 pm

1 stop8h 38m

Lambert-St Louis

Mon 1/12

7:43 pm-10:34 am

2 stops14h 51m

$174

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

Wed 12/31

5:31 pm-11:38 pm

1 stop6h 07m

Lambert-St Louis

Tue 1/13

12:00 pm-7:35 pm

1 stop7h 35m

$178

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

Thu 1/15

5:30 am-11:05 am

1 stop5h 35m

Lambert-St Louis

Sun 1/18

6:10 am-11:47 am

1 stop5h 37m

$178

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/19

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Indiana to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to Missouri

What is the cheapest month to book a flight from Indiana to Missouri?

Currently, September is the cheapest month in which you can book a flight from Indiana to Missouri (average of $75). Flying from Indiana to Missouri in May is currently the most expensive (average of $235). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IN to MO?

Find hourly flight availability from Indiana to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 21, 2025.

A simple way to save on the total cost of your ticket is to fly from Indiana to Missouri in the morning. If you’re flexible enough to do this you can expect to save up to 21% on your trip compared to booking a flight in the evening.

What is the cheapest day to fly from Indiana to Missouri?

Use this chart to determine the cheapest time to fly round-trip from Indiana to Missouri. Price data was last updated on November 18, 2024.

Travelers seeking maximum savings on their Indiana to Missouri flight should consider departing on Tuesday afternoons when fares are most often at their lowest. Saturday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated November 21, 2025.
Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Indiana to Missouri. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,251 reviews

Crew

8.6

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,251 reviews
Southwest
8.0
Very good
4,251 reviews

Crew

8.6

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
8,002 reviews
Southwest
8.0
Very good
4,251 reviews

Crew

8.6

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
9,028 reviews
Southwest
8.0
Very good
4,251 reviews

Crew

8.6

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,047 reviews
Southwest
8.0
Very good
4,251 reviews

Crew

8.6

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Indiana to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Indiana to Missouri?

    Departing from Indiana to Missouri will take you 1h 15m. There are 251 mi between Indiana and Missouri. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Indiana to Missouri one-way?

    To fly one-way, consider booking your trip with Southwest, which is currently one of the cheapest options available, starting at $49. United Airlines flights start at $49 while deals on American Airlines start at $49 one-way.

  • Can I find deals for flights from Indiana to Missouri that include hotel bookings?

    Yes. In addition to deals on Indiana to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to Missouri.

  • Can I find deals for business class flights from Indiana to Missouri?

    Yes. Cheapflights offers flight deals from Indiana to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indiana to Missouri?

    Currently, September is the cheapest month in which you can book a flight from Indiana to Missouri (average of $75). Flying from Indiana to Missouri in May is currently the most expensive (average of $235). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Indiana to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Miami flights
Newark to Fort Lauderdale flights
John F Kennedy Intl to Fort Lauderdale flights
Los Angeles to John F Kennedy Intl flights
LaGuardia to Fort Lauderdale flights
Newark to Miami flights
LaGuardia to Miami flights
John F Kennedy Intl to Los Angeles flights
John F Kennedy Intl to Dallas/Fort Worth flights
Dallas/Fort Worth to LaGuardia flights
LaGuardia to Dallas/Fort Worth flights
Dallas/Fort Worth to John F Kennedy Intl flights
Los Angeles to Newark flights
Newark to Los Angeles flights
Newark to Dallas/Fort Worth flights
Dallas/Fort Worth to Newark flights
John F Kennedy Intl to Orlando flights
Newark to West Palm Beach flights
John F Kennedy Intl to Las Vegas flights
Newark to Orlando flights
San Francisco to John F Kennedy Intl flights
Los Angeles to Seattle flights
Dallas/Fort Worth to Las Vegas flights
Hobby to LaGuardia flights
Atlanta to LaGuardia flights
Seattle to Los Angeles flights
Newark to Las Vegas flights
John F Kennedy Intl to San Francisco flights
Atlanta to John F Kennedy Intl flights
LaGuardia to Orlando flights
Orlando to John F Kennedy Intl flights
San Francisco to Los Angeles flights
Los Angeles to LaGuardia flights
Los Angeles to Dallas/Fort Worth flights
Los Angeles to Honolulu flights
San Francisco to Las Vegas flights
Hobby to Newark flights
San Francisco to Newark flights
Dulles Intl to Dallas/Fort Worth flights
John F Kennedy Intl to West Palm Beach flights
O'Hare Intl to Las Vegas flights
Boston to Fort Lauderdale flights
Seattle to Las Vegas flights
Miami to John F Kennedy Intl flights
Philadelphia to Orlando flights
Fort Lauderdale to John F Kennedy Intl flights
Seattle to Dallas/Fort Worth flights
Fort Lauderdale to Newark flights
John F Kennedy Intl to O'Hare Intl flights
John F Kennedy Intl to Tampa flights

Top 4 airlines flying from Indiana to Missouri

Discover the top 4 airlines that operate flights from Indiana to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$178Average$324FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$213Average$369FlexibilityNo cancel feeOn-time69%
DeltaCheapest$216Average$395FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$221Average$333FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.