$43+ Cheap flights from Indiana to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/11. Fares are subject to change and may not be available on all flights or dates of travel.
IND — STL
Mar 13 — Mar 201
1 adult, Economy
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Find cheap flights from Indiana to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Indiana to MissouriExplore the most affordable flight options available from Indiana to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 11, 2026.
Explore the most affordable flight options available from Indiana to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 11, 2026.
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/141:12 pm
ORD
- STL
Nonstop1h 31m
United Airlines
Tue 3/177:00 pm
STL
- ORD
Nonstop1h 35m
United Airlines
Deal found 2/8![United Airlines logo]()
$93
This Southwest deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1710:30 am
MDW
- STL
Nonstop1h 10m
Southwest
Wed 3/1810:30 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 2/8![Southwest logo]()
$97
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/109:33 pm
ORD
- STL
Nonstop1h 26m
United Airlines
Wed 3/118:17 am
STL
- ORD
Nonstop1h 33m
United Airlines
Deal found 2/10![United Airlines logo]()
$97
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/104:15 pm
ORD
- STL
1 stop5h 10m
Southwest
Wed 3/117:30 am
STL
- ORD
1 stop5h 20m
Southwest
Deal found 2/10![Southwest logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/55:16 pm
MDW
- STL
1 stop18h 33m
Frontier
Mon 3/92:09 pm
STL
- MDW
1 stop8h 10m
Frontier
Deal found 2/9![Frontier logo]()
$128
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/141:12 pm
ORD
- STL
Nonstop1h 31m
United Airlines
Mon 3/167:00 pm
STL
- ORD
Nonstop1h 35m
United Airlines
Deal found 2/8![United Airlines logo]()
$130
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/54:42 pm
ORD
- STL
1 stop19h 07m
Frontier
Mon 3/92:09 pm
STL
- ORD
1 stop18h 14m
Frontier
Deal found 2/9![Frontier logo]()
$131
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/911:15 am
MDW
- STL
Nonstop1h 15m
Southwest
Wed 3/115:40 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 2/10![Southwest logo]()
$134
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/97:42 pm
ORD
- STL
Nonstop1h 25m
United Airlines
Wed 3/118:17 am
STL
- ORD
Nonstop1h 33m
United Airlines
Deal found 2/10![United Airlines logo]()
$134
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/93:18 pm
ORD
- STL
Nonstop1h 23m
American Airlines
Sat 4/115:46 am
STL
- ORD
Nonstop1h 30m
American Airlines
Deal found 2/8![American Airlines logo]()
$135
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/77:47 pm
ORD
- STL
Nonstop1h 25m
American Airlines
Mon 3/98:00 am
STL
- ORD
Nonstop1h 31m
American Airlines
Deal found 2/8![American Airlines logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1912:22 pm
MDW
- STL
1 stop18h 29m
Frontier
Mon 2/238:22 pm
STL
- MDW
1 stop22h 45m
Frontier
Deal found 2/8![Frontier logo]()
$142
Best flights from Indiana to MissouriDiscover carefully curated flight deals from Indiana to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 11, 2026.
Discover carefully curated flight deals from Indiana to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 11, 2026.
This Southwest deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/258:15 am
MDW
- STL
Nonstop1h 20m
Southwest
Wed 4/110:30 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 2/8![Southwest logo]()
$97
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/55:16 pm
MDW
- STL
1 stop18h 33m
Frontier
Mon 3/92:09 pm
STL
- MDW
1 stop8h 10m
Frontier
Deal found 2/9![Frontier logo]()
$128
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/18:15 pm
ORD
- STL
Nonstop1h 32m
United Airlines
Thu 4/27:45 am
STL
- ORD
Nonstop1h 26m
United Airlines
Deal found 2/9![United Airlines logo]()
$134
This American Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/54:35 pm
ORD
- COU
Nonstop1h 30m
American Airlines
Sat 3/75:41 pm
COU
- ORD
Nonstop1h 30m
American Airlines
Deal found 2/7![American Airlines logo]()
$179
This Delta deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/259:50 am
ORD
- STL
1 stop6h 42m
Delta
Wed 4/16:29 am
STL
- ORD
1 stop5h 06m
Delta
Deal found 2/8![Delta logo]()
$191
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1710:30 am
MDW
- STL
Nonstop1h 10m
Southwest
Tue 3/174:00 pm
STL
- MDW
Nonstop1h 05m
Southwest
Deal found 2/10![Southwest logo]()
$97
This Southwest deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/178:15 am
MDW
- STL
Nonstop1h 20m
Southwest
Wed 3/183:10 pm
STL
- MDW
1 stop4h 45m
Southwest
Deal found 2/8![Southwest logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/107:43 pm
CVG
- MCI
1 stop16h 15m
Multiple Airlines
Tue 3/176:04 pm
MCI
- CVG
2 stops19h 20m
Multiple Airlines
Deal found 2/8![Multiple Airlines logo]()
$253
This Southwest deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/172:40 pm
ORD
- STL
1 stop5h 15m
Southwest
Wed 3/186:10 am
STL
- ORD
1 stop5h 00m
Southwest
Deal found 2/8![Southwest logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1912:22 pm
MDW
- STL
1 stop18h 29m
Frontier
Mon 2/238:22 pm
STL
- MDW
1 stop22h 45m
Frontier
Deal found 2/8![Frontier logo]()
$142
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/27:40 pm
ORD
- STL
Nonstop1h 25m
United Airlines
Mon 3/167:40 am
STL
- ORD
Nonstop1h 29m
United Airlines
Deal found 2/8![United Airlines logo]()
$171
This Southwest deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/67:45 am
MDW
- STL
Nonstop1h 15m
Southwest
Wed 4/83:55 pm
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 2/9![Southwest logo]()
$134
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:50 pm
ORD
- COU
Nonstop1h 29m
American Airlines
Mon 3/96:30 pm
COU
- ORD
Nonstop1h 35m
American Airlines
Deal found 2/9![American Airlines logo]()
$179
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/307:40 pm
ORD
- STL
Nonstop1h 28m
United Airlines
Thu 4/27:45 am
STL
- ORD
Nonstop1h 26m
United Airlines
Deal found 2/10![United Airlines logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/271:07 pm
CVG
- STL
1 stop18h 44m
Frontier
Tue 3/33:49 pm
STL
- CVG
1 stop28h 36m
Frontier
Deal found 2/9![Frontier logo]()
$174
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/911:15 am
MDW
- STL
Nonstop1h 15m
Southwest
Wed 3/115:40 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 2/10![Southwest logo]()
$134
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/116:50 pm
ORD
- COU
Nonstop1h 29m
American Airlines
Wed 3/186:30 pm
COU
- ORD
Nonstop1h 35m
American Airlines
Deal found 2/10![American Airlines logo]()
$179
This Delta deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/17:59 pm
IND
- MCI
1 stop4h 04m
Delta
Tue 4/710:37 am
MCI
- IND
1 stop5h 41m
Delta
Deal found 2/8![Delta logo]()
$205
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:00 am
ORD
- STL
Nonstop1h 18m
United Airlines
Sat 5/99:00 am
STL
- ORD
Nonstop1h 24m
United Airlines
Deal found 2/9![United Airlines logo]()
$171
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/68:10 am
ORD
- COU
Nonstop1h 28m
American Airlines
Sun 3/86:30 pm
COU
- ORD
Nonstop1h 35m
American Airlines
Deal found 2/8![American Airlines logo]()
$179
This Frontier deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:05 am
CVG
- MCI
1 stop28h 00m
Frontier
Sat 3/73:40 pm
MCI
- CVG
1 stop6h 57m
Frontier
Deal found 2/10![Frontier logo]()
$182
This Delta deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/253:40 pm
IND
- MCI
1 stop6h 27m
Delta
Fri 2/275:47 pm
MCI
- IND
1 stop5h 20m
Delta
Deal found 2/8![Delta logo]()
$205
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/117:58 pm
ORD
- COU
Nonstop1h 35m
United Airlines
Wed 3/182:41 pm
COU
- ORD
Nonstop1h 28m
United Airlines
Deal found 2/10![United Airlines logo]()
$179
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:50 pm
ORD
- COU
Nonstop1h 29m
American Airlines
Sun 3/810:08 am
COU
- ORD
Nonstop1h 29m
American Airlines
Deal found 2/8![American Airlines logo]()
$180
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/82:40 pm
ORD
- STL
1 stop4h 40m
Southwest
Sat 4/1110:55 am
STL
- ORD
1 stop4h 35m
Southwest
Deal found 2/10![Southwest logo]()
$154
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/235:45 pm
IND
- MCI
1 stop4h 22m
Delta
Tue 2/246:23 am
MCI
- IND
1 stop4h 17m
Delta
Deal found 2/9![Delta logo]()
$205
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2410:55 am
ORD
- MCI
1 stop27h 11m
Multiple Airlines
Sun 4/2612:15 pm
MCI
- ORD
2 stops11h 01m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$256
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/267:27 pm
IND
- MCI
1 stop15h 29m
Frontier
Sun 3/110:53 am
MCI
- IND
1 stop6h 39m
Frontier
Deal found 2/10![Frontier logo]()
$193
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/139:00 am
ORD
- COU
Nonstop1h 33m
United Airlines
Mon 3/168:00 am
COU
- ORD
Nonstop1h 30m
United Airlines
Deal found 2/8![United Airlines logo]()
$179
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/72:40 pm
ORD
- STL
1 stop6h 15m
Southwest
Wed 5/135:45 am
STL
- ORD
1 stop5h 25m
Southwest
Deal found 2/10![Southwest logo]()
$154
Last-minute flights from Indiana to MissouriDiscover last-minute flight deals from Indiana to Missouri. Data last updated February 11, 2026 and is based on user searches.
Discover last-minute flight deals from Indiana to Missouri. Data last updated February 11, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1912:22 pm
MDW
- STL
1 stop18h 29m
Frontier
Mon 2/238:22 pm
STL
- MDW
1 stop22h 45m
Frontier
Deal found 2/8![Frontier logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/55:16 pm
MDW
- STL
1 stop18h 33m
Frontier
Mon 3/92:09 pm
STL
- MDW
1 stop8h 10m
Frontier
Deal found 2/9![Frontier logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/54:42 pm
ORD
- STL
1 stop19h 07m
Frontier
Mon 3/92:09 pm
STL
- ORD
1 stop18h 14m
Frontier
Deal found 2/9![Frontier logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/65:05 am
ORD
- STL
1 stop6h 44m
Frontier
Mon 3/92:09 pm
STL
- ORD
1 stop18h 14m
Frontier
Deal found 2/10![Frontier logo]()
$146
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/77:47 pm
ORD
- STL
Nonstop1h 25m
American Airlines
Mon 3/98:00 am
STL
- ORD
Nonstop1h 31m
American Airlines
Deal found 2/8![American Airlines logo]()
$136
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/911:15 am
MDW
- STL
Nonstop1h 15m
Southwest
Wed 3/115:40 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 2/10![Southwest logo]()
$134
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/97:42 pm
ORD
- STL
Nonstop1h 25m
United Airlines
Wed 3/118:17 am
STL
- ORD
Nonstop1h 33m
United Airlines
Deal found 2/10![United Airlines logo]()
$134
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/107:42 pm
ORD
- STL
Nonstop1h 25m
United Airlines
Tue 3/177:40 am
STL
- ORD
Nonstop1h 29m
United Airlines
Deal found 2/10![United Airlines logo]()
$97
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/104:15 pm
ORD
- STL
1 stop5h 10m
Southwest
Wed 3/117:30 am
STL
- ORD
1 stop5h 20m
Southwest
Deal found 2/10![Southwest logo]()
$117
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/141:12 pm
ORD
- STL
Nonstop1h 31m
United Airlines
Tue 3/177:00 pm
STL
- ORD
Nonstop1h 35m
United Airlines
Deal found 2/8![United Airlines logo]()
$93
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/141:12 pm
ORD
- STL
Nonstop1h 31m
United Airlines
Mon 3/167:00 pm
STL
- ORD
Nonstop1h 35m
United Airlines
Deal found 2/8![United Airlines logo]()
$130
This Southwest deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1710:30 am
MDW
- STL
Nonstop1h 10m
Southwest
Wed 3/1810:30 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 2/8![Southwest logo]()
$97
One-way flights from Indiana to MissouriSearch for one-way flight options from Indiana to Missouri. Find affordable one-way fares based on user searches. Data last updated February 11, 2026.
Search for one-way flight options from Indiana to Missouri. Find affordable one-way fares based on user searches. Data last updated February 11, 2026.
This Southwest deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/76:25 am
MDW
- STL
Nonstop1h 20m
Southwest
Deal found 2/9![Southwest logo]()
$43
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/78:12 pm
ORD
- STL
Nonstop1h 29m
United Airlines
Deal found 2/8![United Airlines logo]()
$45
This Southwest deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/109:05 pm
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 2/9![Southwest logo]()
$49
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/258:12 pm
ORD
- STL
Nonstop1h 30m
United Airlines
Deal found 2/9![United Airlines logo]()
$49
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/113:18 pm
ORD
- STL
Nonstop1h 23m
American Airlines
Deal found 2/9![American Airlines logo]()
$50
This Southwest deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/314:15 pm
ORD
- STL
1 stop5h 10m
Southwest
Deal found 2/8![Southwest logo]()
$59
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/107:41 pm
ORD
- STL
1 stop14h 56m
Frontier
Deal found 2/8![Frontier logo]()
$61
This Southwest deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/31:20 pm
MDW
- STL
2 stops7h 15m
Southwest
Deal found 2/9![Southwest logo]()
$64
This Southwest deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1511:55 am
ORD
- STL
1 stop9h 20m
Southwest
Deal found 2/9![Southwest logo]()
$64
This Southwest deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/147:55 am
MDW
- MCI
Nonstop1h 35m
Southwest
Deal found 2/9![Southwest logo]()
$67
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/55:16 pm
MDW
- STL
1 stop18h 33m
Frontier
Deal found 2/9![Frontier logo]()
$67
This Trip.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/221:07 pm
CVG
- STL
1 stop18h 44m
Frontier
Deal found 2/8![Frontier logo]()
$67
Find flight deals from Indiana to Missouri
Keep the following information in mind while searching for Indiana to Missouri flight deals. Data was last updated February 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $93 (United Airlines) |
One-way from | $43 (Southwest) |
Popular in | September |
Cheapest in | November |
Average price | $460 |
Good round-trip deal | $404 or less |
Good one-way deal | $204 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Indiana to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 11, 2026.
Use the filters below to find and compare flights from Indiana to Missouri that are best for you.
Fly from
Indiana
Fly to
Missouri
Route
Depart
Return
Price
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Wed 3/25
8:15 am-9:35 am
Nonstop1h 20m
Lambert-St Louis
Wed 4/1
10:30 am-11:40 am
Nonstop1h 10m
$97
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Tue 3/17
10:30 am-11:40 am
Nonstop1h 10m
Lambert-St Louis
Tue 3/17
4:00 pm-5:05 pm
Nonstop1h 05m
$97
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Tue 3/17
8:15 am-9:35 am
Nonstop1h 20m
Lambert-St Louis
Wed 3/18
3:10 pm-7:55 pm
1 stop4h 45m
$107
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Tue 3/17
2:40 pm-7:55 pm
1 stop5h 15m
Lambert-St Louis
Wed 3/18
6:10 am-11:10 am
1 stop5h 00m
$117
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Thu 3/5
5:16 pm-11:49 am
1 stop18h 33m
Lambert-St Louis
Mon 3/9
2:09 pm-10:19 pm
1 stop8h 10m
$128
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Wed 4/1
8:15 pm-9:47 pm
Nonstop1h 32m
Lambert-St Louis
Thu 4/2
7:45 am-9:11 am
Nonstop1h 26m
$134
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Mon 4/6
7:45 am-9:00 am
Nonstop1h 15m
Lambert-St Louis
Wed 4/8
3:55 pm-5:05 pm
Nonstop1h 10m
$134
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Mon 3/9
11:15 am-12:30 pm
Nonstop1h 15m
Lambert-St Louis
Wed 3/11
5:40 am-6:50 am
Nonstop1h 10m
$134
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Thu 2/19
12:22 pm-6:51 am
1 stop18h 29m
Lambert-St Louis
Mon 2/23
8:22 pm-7:07 pm
1 stop22h 45m
$142
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Wed 4/8
2:40 pm-7:20 pm
1 stop4h 40m
Lambert-St Louis
Sat 4/11
10:55 am-3:30 pm
1 stop4h 35m
$154
Showing 1-10 of 60 results
Best time to book a flight from Indiana to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Indiana with our price prediction graph.
MDW-STL
ORD-STL
CVG-STL
MDW-MCI
IND-MCI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Indiana to Missouri
USIN-USMO
MDW-STL
ORD-STL
CVG-STL
MDW-MCI
What is the cheapest month to book a flight from Indiana to Missouri?
Currently, September is the cheapest month in which you can book a flight from Indiana to Missouri (average of $75). Flying from Indiana to Missouri in March is currently the most expensive (average of $239). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from IN to MO?
Find hourly flight availability from Indiana to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 11, 2026.
A simple way to save on the total cost of your ticket is to fly from Indiana to Missouri in the morning. If you’re flexible enough to do this you can expect to save up to 79% on your trip compared to booking a flight in the evening.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated February 11, 2026.
Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Indiana to Missouri. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Indiana to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Indiana to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Indiana to Missouri by cabin class
Find flights from Indiana to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Indiana and Missouri flights
Browse other Indiana and Missouri flight options. Last updated on February 11, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Indiana after your stay in Missouri
Indiana to Missouri flights
Consider these flights traveling from Indiana to Missouri.
Top 4 airlines flying from Indiana to Missouri
Discover the top 4 airlines that operate flights from Indiana to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$178 | Average$335 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$198 | Average$305 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$213 | Average$367 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$221 | Average$335 | FlexibilityNo cancel fee | On-time63% |