$59+ Cheap flights from Indiana to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/6. Fares are subject to change and may not be available on all flights or dates of travel.
IND — STL
May 9 — May 161
Round-trip
1 adult, Economy
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Find cheap flights from Indiana to Missouri with Cheapflights
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Cheapest flights from Indiana to MissouriExplore the most affordable flight options available from Indiana to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 9, 2026.
Explore the most affordable flight options available from Indiana to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 9, 2026.
This Frontier deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:17 pm
CVG
- MCI
1 stop18h 49m
Frontier
Sat 5/92:34 pm
MCI
- CVG
1 stop19h 10m
Frontier
Deal found 4/7![Frontier logo]()
$142
This Priceline deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:20 pm
CVG
- STL
1 stop6h 59m
Frontier
Sun 5/311:28 am
STL
- CVG
1 stop5h 48m
Frontier
Deal found 4/6![Frontier logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/812:46 pm
CVG
- MCI
1 stop5h 43m
Frontier
Wed 6/106:19 pm
MCI
- CVG
1 stop15h 55m
Frontier
Deal found 4/5![Frontier logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/612:46 pm
CVG
- MCI
1 stop5h 43m
Frontier
Wed 6/106:19 pm
MCI
- CVG
1 stop15h 55m
Frontier
Deal found 4/7![Frontier logo]()
$163
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:12 pm
CVG
- STL
1 stop6h 21m
Frontier
Mon 6/15:27 pm
STL
- CVG
1 stop16h 37m
Frontier
Deal found 4/6![Frontier logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/51:48 pm
CVG
- STL
2 stops20h 07m
Frontier
Thu 5/76:55 pm
STL
- CVG
1 stop15h 46m
Frontier
Deal found 4/7![Frontier logo]()
$175
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/24:26 pm
CVG
- STL
1 stop7h 53m
Frontier
Sat 5/95:27 pm
STL
- CVG
1 stop16h 37m
Frontier
Deal found 4/4![Frontier logo]()
$183
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2811:28 am
ORD
- STL
1 stop19h 22m
Multiple Airlines
Fri 5/18:23 pm
STL
- ORD
2 stops19h 00m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$190
This CheapOair deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/812:14 pm
IND
- MCI
1 stop6h 15m
Frontier
Sat 5/92:34 pm
MCI
- IND
1 stop28h 20m
Frontier
Deal found 4/5![Frontier logo]()
$191
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/309:30 pm
MDW
- STL
Nonstop1h 15m
Southwest
Mon 5/47:20 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 4/7![Southwest logo]()
$191
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/303:18 pm
ORD
- STL
Nonstop1h 23m
American Airlines
Mon 5/44:30 pm
STL
- ORD
Nonstop1h 40m
American Airlines
Deal found 4/8![American Airlines logo]()
$191
This CheapOair deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:39 pm
IND
- MCI
1 stop18h 10m
Frontier
Sun 5/102:34 pm
MCI
- IND
1 stop28h 20m
Frontier
Deal found 4/4![Frontier logo]()
$192
Best flights from Indiana to MissouriDiscover carefully curated flight deals from Indiana to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 9, 2026.
Discover carefully curated flight deals from Indiana to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 9, 2026.
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/309:30 pm
MDW
- STL
Nonstop1h 15m
Southwest
Mon 5/49:40 pm
STL
- MDW
Nonstop1h 05m
Southwest
Deal found 4/8![Southwest logo]()
$191
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/511:15 am
ORD
- STL
1 stop5h 48m
American Airlines
Tue 5/127:05 am
STL
- ORD
Nonstop1h 31m
American Airlines
Deal found 4/8![American Airlines logo]()
$197
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/169:20 pm
ORD
- STL
Nonstop1h 25m
United Airlines
Tue 5/197:09 pm
STL
- ORD
Nonstop1h 31m
United Airlines
Deal found 4/5![United Airlines logo]()
$224
This Frontier deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1812:12 pm
CVG
- STL
1 stop6h 18m
Frontier
Sun 6/214:10 pm
STL
- CVG
1 stop6h 36m
Frontier
Deal found 4/8![Frontier logo]()
$250
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/259:27 am
MDW
- STL
2 stops7h 23m
Delta
Mon 4/276:48 am
STL
- MDW
1 stop5h 55m
Delta
Deal found 4/4![Delta logo]()
$250
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/49:30 pm
MDW
- STL
Nonstop1h 15m
Southwest
Mon 5/1110:15 am
STL
- MDW
1 stop5h 10m
Southwest
Deal found 4/5![Southwest logo]()
$201
This Southwest deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/255:15 am
MDW
- STL
1 stop6h 10m
Southwest
Mon 4/274:00 pm
STL
- MDW
1 stop6h 20m
Southwest
Deal found 4/4![Southwest logo]()
$211
This United Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/298:08 pm
ORD
- COU
Nonstop1h 51m
United Airlines
Tue 8/48:00 am
COU
- ORD
Nonstop1h 40m
United Airlines
Deal found 4/3![United Airlines logo]()
$239
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:56 pm
ORD
- COU
Nonstop1h 34m
American Airlines
Wed 5/134:28 pm
COU
- ORD
Nonstop1h 42m
American Airlines
Deal found 4/6![American Airlines logo]()
$239
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/37:10 am
ORD
- STL
1 stop4h 46m
Delta
Wed 5/612:23 pm
STL
- ORD
2 stops8h 17m
Delta
Deal found 4/7![Delta logo]()
$252
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/274:15 pm
ORD
- STL
1 stop6h 25m
Southwest
Thu 4/308:25 am
STL
- ORD
1 stop6h 35m
Southwest
Deal found 4/6![Southwest logo]()
$211
This United Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/28:20 pm
ORD
- COU
Nonstop1h 43m
United Airlines
Sat 5/95:00 am
COU
- ORD
Nonstop1h 30m
United Airlines
Deal found 4/4![United Airlines logo]()
$239
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/184:25 pm
ORD
- COU
Nonstop1h 37m
American Airlines
Sun 6/216:32 pm
COU
- ORD
Nonstop1h 50m
American Airlines
Deal found 4/7![American Airlines logo]()
$239
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/155:10 pm
MDW
- STL
1 stop6h 49m
Delta
Sat 5/164:00 pm
STL
- MDW
1 stop5h 09m
Delta
Deal found 4/5![Delta logo]()
$254
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2811:35 am
MDW
- STL
2 stops6h 20m
Southwest
Fri 5/19:40 pm
STL
- MDW
Nonstop1h 05m
Southwest
Deal found 4/7![Southwest logo]()
$212
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/243:32 pm
CVG
- STL
2 stops16h 18m
Frontier
Sun 4/2611:44 am
STL
- CVG
1 stop5h 04m
Frontier
Deal found 4/4![Frontier logo]()
$292
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/298:20 am
ORD
- COU
Nonstop1h 40m
American Airlines
Tue 8/45:19 pm
COU
- ORD
1 stop7h 12m
American Airlines
Deal found 4/3![American Airlines logo]()
$248
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/11:36 pm
ORD
- STL
2 stops9h 37m
Delta
Mon 5/44:41 pm
STL
- ORD
1 stop4h 44m
Delta
Deal found 4/4![Delta logo]()
$259
This United Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/58:08 pm
ORD
- COU
Nonstop1h 51m
United Airlines
Sun 6/78:00 am
COU
- ORD
Nonstop1h 40m
United Airlines
Deal found 4/7![United Airlines logo]()
$259
This Southwest deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/27:45 am
MDW
- STL
1 stop5h 50m
Southwest
Sat 5/95:15 am
STL
- MDW
2 stops6h 55m
Southwest
Deal found 4/4![Southwest logo]()
$216
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/278:20 am
ORD
- COU
Nonstop1h 40m
American Airlines
Sun 6/2810:30 am
COU
- ORD
Nonstop1h 34m
American Airlines
Deal found 4/5![American Airlines logo]()
$254
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/121:16 pm
MDW
- STL
2 stops10h 07m
Delta
Tue 6/163:57 pm
STL
- MDW
1 stop6h 20m
Delta
Deal found 4/5![Delta logo]()
$262
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/228:09 pm
ORD
- SGF
Nonstop1h 55m
United Airlines
Mon 4/276:50 pm
SGF
- ORD
Nonstop1h 48m
United Airlines
Deal found 4/5![United Airlines logo]()
$264
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/511:35 am
MDW
- STL
2 stops6h 20m
Southwest
Tue 5/121:15 pm
STL
- MDW
2 stops6h 20m
Southwest
Deal found 4/7![Southwest logo]()
$223
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/93:22 pm
ORD
- SGF
1 stop6h 48m
Delta
Mon 7/136:58 pm
SGF
- ORD
1 stop4h 55m
Delta
Deal found 4/5![Delta logo]()
$269
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/228:15 am
ORD
- COU
Nonstop1h 31m
American Airlines
Sun 4/2610:16 am
COU
- ORD
Nonstop1h 31m
American Airlines
Deal found 4/8![American Airlines logo]()
$269
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:09 pm
CVG
- MCI
1 stop4h 55m
United Airlines
Tue 5/123:22 pm
MCI
- CVG
1 stop4h 08m
United Airlines
Deal found 4/5![United Airlines logo]()
$273
This Southwest deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1411:40 am
MDW
- STL
Nonstop1h 15m
Southwest
Sun 5/175:25 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 4/4![Southwest logo]()
$234
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/134:50 pm
MDW
- STL
1 stop6h 55m
Southwest
Wed 6/175:55 pm
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 4/7![Southwest logo]()
$237
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/166:24 am
ORD
- STL
1 stop4h 08m
Delta
Sun 5/246:21 am
STL
- ORD
2 stops6h 35m
Delta
Deal found 4/5![Delta logo]()
$289
Last-minute flights from Indiana to MissouriDiscover last-minute flight deals from Indiana to Missouri. Data last updated April 9, 2026 and is based on user searches.
Discover last-minute flight deals from Indiana to Missouri. Data last updated April 9, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2811:28 am
ORD
- STL
1 stop19h 22m
Multiple Airlines
Fri 5/18:23 pm
STL
- ORD
2 stops19h 00m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$190
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/309:30 pm
MDW
- STL
Nonstop1h 15m
Southwest
Mon 5/47:20 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 4/7![Southwest logo]()
$191
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/303:18 pm
ORD
- STL
Nonstop1h 23m
American Airlines
Mon 5/44:30 pm
STL
- ORD
Nonstop1h 40m
American Airlines
Deal found 4/8![American Airlines logo]()
$191
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/308:21 am
MDW
- STL
1 stop14h 58m
Frontier
Mon 5/48:23 pm
STL
- MDW
1 stop14h 46m
Frontier
Deal found 4/7![Frontier logo]()
$192
This Frontier deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:17 pm
CVG
- MCI
1 stop18h 49m
Frontier
Sat 5/92:34 pm
MCI
- CVG
1 stop19h 10m
Frontier
Deal found 4/7![Frontier logo]()
$142
This Priceline deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:20 pm
CVG
- STL
1 stop6h 59m
Frontier
Sun 5/311:28 am
STL
- CVG
1 stop5h 48m
Frontier
Deal found 4/6![Frontier logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/24:26 pm
CVG
- STL
1 stop7h 53m
Frontier
Sat 5/95:27 pm
STL
- CVG
1 stop16h 37m
Frontier
Deal found 4/4![Frontier logo]()
$183
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/51:48 pm
CVG
- STL
2 stops20h 07m
Frontier
Thu 5/76:55 pm
STL
- CVG
1 stop15h 46m
Frontier
Deal found 4/7![Frontier logo]()
$175
This CheapOair deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/812:14 pm
IND
- MCI
1 stop6h 15m
Frontier
Sat 5/92:34 pm
MCI
- IND
1 stop28h 20m
Frontier
Deal found 4/5![Frontier logo]()
$191
This CheapOair deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:39 pm
IND
- MCI
1 stop18h 10m
Frontier
Sun 5/102:34 pm
MCI
- IND
1 stop28h 20m
Frontier
Deal found 4/4![Frontier logo]()
$192
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/233:20 pm
ORD
- STL
Nonstop1h 32m
American Airlines
Sat 5/308:02 pm
STL
- ORD
Nonstop1h 43m
American Airlines
Deal found 4/8![American Airlines logo]()
$192
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:12 pm
CVG
- STL
1 stop6h 21m
Frontier
Mon 6/15:27 pm
STL
- CVG
1 stop16h 37m
Frontier
Deal found 4/6![Frontier logo]()
$164
One-way flights from Indiana to MissouriSearch for one-way flight options from Indiana to Missouri. Find affordable one-way fares based on user searches. Data last updated April 9, 2026.
Search for one-way flight options from Indiana to Missouri. Find affordable one-way fares based on user searches. Data last updated April 9, 2026.
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/61:55 pm
MDW
- STL
Nonstop1h 10m
Southwest
Deal found 4/6![Southwest logo]()
$59
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/610:30 pm
ORD
- STL
Nonstop1h 16m
American Airlines
Deal found 4/8![American Airlines logo]()
$59
This Trip.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/912:12 pm
CVG
- STL
1 stop6h 18m
Frontier
Deal found 4/4![Frontier logo]()
$60
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2912:54 pm
CVG
- MCI
1 stop5h 30m
Frontier
Deal found 4/6![Frontier logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/2312:12 pm
CVG
- STL
1 stop6h 18m
Frontier
Deal found 4/6![Frontier logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1912:54 pm
CVG
- MCI
1 stop29h 30m
Frontier
Deal found 4/4![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1012:14 pm
IND
- MCI
1 stop6h 10m
Frontier
Deal found 4/8![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1612:12 pm
CVG
- STL
1 stop21h 40m
Frontier
Deal found 4/6![Frontier logo]()
$65
This Trip.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/247:46 pm
CVG
- STL
1 stop12h 04m
Frontier
Deal found 4/4![Frontier logo]()
$66
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2811:28 am
ORD
- STL
1 stop19h 22m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$66
This Trip.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/266:53 pm
CVG
- STL
1 stop12h 57m
Frontier
Deal found 4/4![Frontier logo]()
$67
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/62:40 pm
ORD
- STL
1 stop4h 35m
Southwest
Deal found 4/6![Southwest logo]()
$69
Find flight deals from Indiana to Missouri
Keep the following information in mind while searching for Indiana to Missouri flight deals. Data was last updated April 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $130 (Kiwi.com) |
One-way from | $59 (Southwest) |
Popular in | September |
Cheapest in | November |
Average price | $311 |
Good round-trip deal | $307 or less |
Good one-way deal | $183 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Indiana to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 9, 2026.
Use the filters below to find and compare flights from Indiana to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Thu 4/30
9:30 pm-10:45 pm
Nonstop1h 15m
Lambert-St Louis
Mon 5/4
9:40 pm-10:45 pm
Nonstop1h 05m
$191
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Tue 5/5
11:15 am-5:03 pm
1 stop5h 48m
Lambert-St Louis
Tue 5/12
7:05 am-8:36 am
Nonstop1h 31m
$197
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Mon 5/4
9:30 pm-10:45 pm
Nonstop1h 15m
Lambert-St Louis
Mon 5/11
10:15 am-3:25 pm
1 stop5h 10m
$201
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Sat 4/25
5:15 am-11:25 am
1 stop6h 10m
Lambert-St Louis
Mon 4/27
4:00 pm-10:20 pm
1 stop6h 20m
$211
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Mon 4/27
4:15 pm-10:40 pm
1 stop6h 25m
Lambert-St Louis
Thu 4/30
8:25 am-3:00 pm
1 stop6h 35m
$211
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Tue 4/28
11:35 am-5:55 pm
2 stops6h 20m
Lambert-St Louis
Fri 5/1
9:40 pm-10:45 pm
Nonstop1h 05m
$212
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Sat 5/2
7:45 am-1:35 pm
1 stop5h 50m
Lambert-St Louis
Sat 5/9
5:15 am-12:10 pm
2 stops6h 55m
$216
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Tue 5/5
11:35 am-5:55 pm
2 stops6h 20m
Lambert-St Louis
Tue 5/12
1:15 pm-7:35 pm
2 stops6h 20m
$223
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Sat 5/16
9:20 pm-10:45 pm
Nonstop1h 25m
Lambert-St Louis
Tue 5/19
7:09 pm-8:40 pm
Nonstop1h 31m
$224
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Thu 5/14
11:40 am-12:55 pm
Nonstop1h 15m
Lambert-St Louis
Sun 5/17
5:25 am-6:35 am
Nonstop1h 10m
$234
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Indiana to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Indiana with our price prediction graph.
MDW-STL
ORD-STL
CVG-STL
CVG-MCI
IND-MCI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Indiana to Missouri
USIN-USMO
MDW-STL
ORD-STL
CVG-STL
CVG-MCI
What is the cheapest month to book a flight from Indiana to Missouri?
Currently, September is the cheapest month in which you can book a flight from Indiana to Missouri (average of $75). Flying from Indiana to Missouri in March is currently the most expensive (average of $239). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from IN to MO?
Find hourly flight availability from Indiana to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 9, 2026.
A simple way to save on the total cost of your ticket is to fly from Indiana to Missouri at noon. If you’re flexible enough to do this you can expect to save up to 79% on your trip compared to booking a flight in the evening.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated April 9, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Indiana to Missouri. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Crew
8.6
Overall
8.0
Food
7.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Crew
8.6
Overall
8.0
Food
7.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Crew
8.6
Overall
8.0
Food
7.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Crew
8.6
Overall
8.0
Food
7.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Crew
8.6
Overall
8.0
Food
7.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Indiana to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Indiana to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Indiana to Missouri by cabin class
Find flights from Indiana to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Indiana and Missouri flights
Browse other Indiana and Missouri flight options. Last updated on April 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Indiana after your stay in Missouri
Indiana to Missouri flights
Consider these flights traveling from Indiana to Missouri.
Top 4 airlines flying from Indiana to Missouri
Discover the top 4 airlines that operate flights from Indiana to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$178 | Average$337 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$218 | Average$355 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$221 | Average$327 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$228 | Average$342 | FlexibilityNo cancel fee | On-time69% |