HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Missouri

$64+ Cheap flights from Indiana to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/24. Fares are subject to change and may not be available on all flights or dates of travel.
IND — STL
feb. 19 — feb. 261
jue. 2/19
jue. 2/26
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Indiana to Missouri with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Indiana to Missouri

Cheapest flights from Indiana to Missouri
Explore the most affordable flight options available from Indiana to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 20, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 2/246:02 pm
ORD
-
STL
1 stop12h 49m
Frontier
jue. 2/2610:11 pm
STL
-
ORD
1 stop19h 15m
Frontier
Deal found 1/20$129
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 2/199:05 am
MDW
-
STL
1 stop21h 46m
Frontier
lun. 2/238:22 pm
STL
-
MDW
1 stop22h 45m
Frontier
Deal found 1/19$135
This Kiwi.com deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 2/194:42 pm
ORD
-
STL
1 stop14h 09m
Frontier
lun. 2/238:22 pm
STL
-
ORD
1 stop14h 29m
Frontier
Deal found 1/18$146
This Kiwi.com deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 2/206:48 pm
MDW
-
STL
1 stop12h 03m
Frontier
lun. 2/238:22 pm
STL
-
MDW
1 stop22h 45m
Frontier
Deal found 1/18$152
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 2/32:53 pm
ORD
-
STL
1 stop15h 58m
Frontier
vie. 2/68:22 pm
STL
-
ORD
1 stop26h 22m
Frontier
Deal found 1/20$154
This Kiwi.com deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 2/176:02 pm
ORD
-
STL
1 stop12h 49m
Multiple Airlines
mar. 2/243:49 pm
STL
-
ORD
1 stop25h 57m
Multiple Airlines
Deal found 1/18$155
This Frontier deal was found by Cheapflights users on 1/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/75:15 am
ORD
-
STL
1 stop5h 15m
Frontier
jue. 4/911:21 am
STL
-
ORD
1 stop11h 23m
Frontier
Deal found 1/17$160
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 2/197:27 pm
IND
-
MCI
1 stop15h 36m
Frontier
lun. 2/2310:55 am
MCI
-
IND
1 stop6h 36m
Frontier
Deal found 1/19$163
This Kiwi.com deal was found by Cheapflights users on 1/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 2/278:32 pm
IND
-
MCI
1 stop24h 14m
Frontier
dom. 3/88:40 pm
MCI
-
IND
1 stop21h 58m
Frontier
Deal found 1/17$166
This Mytrip deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 2/211:51 am
ORD
-
STL
1 stop11h 42m
Frontier
jue. 2/55:42 pm
STL
-
ORD
1 stop16h 53m
Frontier
Deal found 1/19$169
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 2/187:00 am
MDW
-
STL
2 stops40h 59m
Frontier
mié. 2/258:17 pm
STL
-
MDW
1 stop26h 12m
Frontier
Deal found 1/19$175
This Expedia deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/33:20 pm
CVG
-
STL
1 stop8h 07m
Frontier
mar. 3/104:51 pm
STL
-
CVG
1 stop6h 50m
Frontier
Deal found 1/18$175

Find flight deals from Indiana to Missouri

Keep the following information in mind while searching for Indiana to Missouri flight deals. Data was last updated enero 20, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$129
(Kiwi.com)

One-way from

$64
(Frontier)

Popular in

September

Cheapest in

November

Average price

$386

Good round-trip deal

$438 or less

Good one-way deal

$233 or less
Provider with most accurate pricing for Indianapolis-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Indianapolis-Lambert-St Louis flights.
Search Deals
From Indiana to Missouri
Search Deals
One-way flight from Indiana to Missouri
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($35 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals
Price to beat on a round-trip flight from Indiana to Missouri.
Search Deals
Price to beat on a one-way flight from Indiana to Missouri.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indiana to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 20, 2026.
Use the filters below to find and compare flights from Indiana to Missouri that are best for you.

Fly from

Indiana

Fly to

Missouri

Route

Depart

Return

Price

IndianapolisKansas City

IND - MCI

INDMCI

Indianapolis

jue. 2/19

7:27 pm-10:03 am

1 stop15h 36m

Kansas City

lun. 2/23

10:55 am-6:31 pm

1 stop6h 36m

$163

IndianapolisKansas City

IND - MCI

INDMCI

Indianapolis

vie. 2/27

8:32 pm-7:46 pm

1 stop24h 14m

Kansas City

dom. 3/8

8:40 pm-7:38 pm

1 stop21h 58m

$166

CincinnatiSt. Louis

CVG - STL

CVGSTL

Cincinnati Cinci./N. Kentucky

mar. 3/3

3:20 pm-10:27 pm

1 stop8h 07m

Lambert-St Louis

mar. 3/10

4:51 pm-12:41 am

1 stop6h 50m

$175

ChicagoColumbia

ORD - COU

ORDCOU

Chicago O'Hare Intl

vie. 2/13

9:00 am-10:33 am

Nonstop1h 33m

Columbia Regional

dom. 2/15

11:15 am-12:45 pm

Nonstop1h 30m

$179

ChicagoColumbia

ORD - COU

ORDCOU

Chicago O'Hare Intl

vie. 4/3

6:50 pm-8:19 pm

Nonstop1h 29m

Columbia Regional

sáb. 4/4

6:50 pm-8:25 pm

Nonstop1h 35m

$179

ChicagoColumbia

ORD - COU

ORDCOU

Chicago O'Hare Intl

mar. 2/17

1:00 pm-2:28 pm

Nonstop1h 28m

Columbia Regional

mar. 2/24

8:00 am-9:30 am

Nonstop1h 30m

$179

ChicagoColumbia

ORD - COU

ORDCOU

Chicago O'Hare Intl

vie. 2/27

6:50 pm-8:19 pm

Nonstop1h 29m

Columbia Regional

dom. 3/1

6:00 am-7:36 am

Nonstop1h 36m

$179

ChicagoColumbia

ORD - COU

ORDCOU

Chicago O'Hare Intl

mié. 2/11

7:58 pm-9:37 pm

Nonstop1h 39m

Columbia Regional

dom. 2/15

11:15 am-12:45 pm

Nonstop1h 30m

$179

ChicagoColumbia

ORD - COU

ORDCOU

Chicago O'Hare Intl

jue. 2/12

4:35 pm-6:05 pm

Nonstop1h 30m

Columbia Regional

dom. 2/15

6:00 am-7:36 am

Nonstop1h 36m

$179

ChicagoColumbia

ORD - COU

ORDCOU

Chicago O'Hare Intl

jue. 2/12

9:00 am-10:33 am

Nonstop1h 33m

Columbia Regional

dom. 2/15

11:15 am-12:45 pm

Nonstop1h 30m

$179

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Indiana to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to Missouri

What is the cheapest month to book a flight from Indiana to Missouri?

Currently, September is the cheapest month in which you can book a flight from Indiana to Missouri (average of $75). Flying from Indiana to Missouri in May is currently the most expensive (average of $227). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IN to MO?

Find hourly flight availability from Indiana to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated enero 20, 2026.

A simple way to save on the total cost of your ticket is to fly from Indiana to Missouri in the morning. If you’re flexible enough to do this you can expect to save up to 79% on your trip compared to booking a flight in the evening.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated enero 20, 2026.
Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Indiana to Missouri. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,267 reviews

Crew

8.6

Comfort

8.0

Food

7.0

Boarding

8.1

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,267 reviews
Southwest
8.0
Very good
4,267 reviews

Crew

8.6

Comfort

8.0

Food

7.0

Boarding

8.1

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,076 reviews
Southwest
8.0
Very good
4,267 reviews

Crew

8.6

Comfort

8.0

Food

7.0

Boarding

8.1

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,180 reviews
Southwest
8.0
Very good
4,267 reviews

Crew

8.6

Comfort

8.0

Food

7.0

Boarding

8.1

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,164 reviews
Southwest
8.0
Very good
4,267 reviews

Crew

8.6

Comfort

8.0

Food

7.0

Boarding

8.1

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Indiana to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Indiana to Missouri?

    Departing from Indiana to Missouri will take you 1h 29m. There are 315 mi between Indiana and Missouri. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Indiana to Missouri one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $98. Delta flights start at $100 while deals on Southwest start at $118 one-way.

  • Can I find deals for flights from Indiana to Missouri that include hotel bookings?

    Yes. In addition to deals on Indiana to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to Missouri.

  • Can I find deals for business class flights from Indiana to Missouri?

    Yes. Cheapflights offers flight deals from Indiana to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indiana to Missouri?

    Currently, September is the cheapest month in which you can book a flight from Indiana to Missouri (average of $75). Flying from Indiana to Missouri in May is currently the most expensive (average of $227). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Indiana to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
Newark to Fort Lauderdale flights
John F Kennedy Intl to Fort Lauderdale flights
Newark to Miami flights
John F Kennedy Intl to Miami flights
LaGuardia to Fort Lauderdale flights
LaGuardia to Miami flights
Newark to West Palm Beach flights
John F Kennedy Intl to West Palm Beach flights
John F Kennedy Intl to Orlando flights
John F Kennedy Intl to Los Angeles flights
John F Kennedy Intl to Las Vegas flights
Minneapolis to Sky Harbor Intl flights
O'Hare Intl to Sky Harbor Intl flights
Newark to Las Vegas flights
O'Hare Intl to Las Vegas flights
Los Angeles to Seattle flights
Newark to Orlando flights
Boston to Denver flights
Detroit to Orlando flights
Newark to Tampa flights
Boston to Fort Lauderdale flights
Dallas/Fort Worth to John F Kennedy Intl flights
Los Angeles to John F Kennedy Intl flights
John F Kennedy Intl to Tampa flights
O'Hare Intl to Dallas/Fort Worth flights
LaGuardia to Orlando flights
Seattle to Las Vegas flights
Dallas/Fort Worth to Las Vegas flights
Seattle to Los Angeles flights
John F Kennedy Intl to Sky Harbor Intl flights
Boston to Miami flights
LaGuardia to Tampa flights
LaGuardia to West Palm Beach flights
Los Angeles to Honolulu flights
Newark to Sky Harbor Intl flights
Minneapolis to Orlando flights
Detroit to Fort Lauderdale flights
Dallas/Fort Worth to Seattle flights
Baltimore to Fort Lauderdale flights
Reagan-National to Miami flights
Newark to Los Angeles flights
John F Kennedy Intl to San Francisco flights
Dulles Intl to Las Vegas flights
Dulles Intl to Miami flights
Boston to Tampa flights
John F Kennedy Intl to Dallas/Fort Worth flights
Seattle to Sky Harbor Intl flights
San Francisco to Las Vegas flights
San Francisco to John F Kennedy Intl flights
Philadelphia to Miami flights

Top 4 airlines flying from Indiana to Missouri

Discover the top 4 airlines that operate flights from Indiana to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 20, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$178Average$343FlexibilityNo cancel feeOn-time71%
DeltaCheapest$198Average$303FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$213Average$362FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$221Average$333FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.