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$49+ Cheap flights from Indiana to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/17. Fares are subject to change and may not be available on all flights or dates of travel.
IND — STL
Feb 26 — Mar 51
Thu 2/26
Thu 3/5
1 adult, Economy
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Cheap flight deals from Indiana to Missouri

Cheapest flights from Indiana to Missouri
Explore the most affordable flight options available from Indiana to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.

This Southwest deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/246:10 am
MDW
-
STL
Nonstop1h 25m
Southwest
Tue 3/38:20 am
STL
-
MDW
Nonstop1h 10m
Southwest
Deal found 1/26$97
This Southwest deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/242:15 pm
ORD
-
STL
1 stop6h 20m
Southwest
Tue 3/36:20 am
STL
-
ORD
1 stop6h 40m
Southwest
Deal found 1/26$117
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/176:02 pm
ORD
-
STL
1 stop12h 49m
Frontier
Fri 2/208:20 pm
STL
-
ORD
1 stop26h 19m
Frontier
Deal found 1/26$133
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:10 am
MDW
-
STL
Nonstop1h 25m
Southwest
Thu 3/52:15 pm
STL
-
MDW
Nonstop1h 05m
Southwest
Deal found 1/27$134
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/38:10 am
ORD
-
STL
Nonstop1h 23m
American Airlines
Thu 3/56:00 am
STL
-
ORD
Nonstop1h 28m
American Airlines
Deal found 1/27$134
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/38:30 am
ORD
-
STL
1 stop13h 57m
Frontier
Fri 3/61:09 pm
STL
-
ORD
1 stop9h 30m
Frontier
Deal found 1/27$139
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/176:02 pm
ORD
-
STL
1 stop12h 49m
Frontier
Wed 2/188:17 pm
STL
-
ORD
1 stop14h 34m
Frontier
Deal found 1/27$142
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/17:27 pm
IND
-
MCI
1 stop15h 26m
Frontier
Wed 3/44:39 pm
MCI
-
IND
1 stop26h 18m
Frontier
Deal found 1/26$145
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1912:22 pm
MDW
-
STL
1 stop18h 29m
Frontier
Mon 2/238:22 pm
STL
-
MDW
1 stop22h 45m
Frontier
Deal found 1/27$145
This Frontier deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/233:50 pm
ORD
-
STL
1 stop8h 09m
Frontier
Mon 3/23:49 pm
STL
-
ORD
1 stop7h 26m
Frontier
Deal found 1/26$148
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/195:05 am
ORD
-
STL
1 stop25h 46m
Frontier
Mon 2/238:22 pm
STL
-
ORD
1 stop14h 29m
Frontier
Deal found 1/26$151
This Kiwi.com deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/31:20 pm
MDW
-
STL
1 stop17h 31m
Frontier
Fri 2/68:22 pm
STL
-
MDW
1 stop12h 21m
Frontier
Deal found 1/24$154

Find flight deals from Indiana to Missouri

Keep the following information in mind while searching for Indiana to Missouri flight deals. Data was last updated January 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$97
(Southwest)

One-way from

$49
(Southwest)

Popular in

September

Cheapest in

November

Average price

$386

Good round-trip deal

$413 or less

Good one-way deal

$218 or less
Provider with most accurate pricing for Indianapolis-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Indianapolis-Lambert-St Louis flights.
Search Deals
From Indiana to Missouri
Search Deals
One-way flight from Indiana to Missouri
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($35 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals
Price to beat on a round-trip flight from Indiana to Missouri.
Search Deals
Price to beat on a one-way flight from Indiana to Missouri.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indiana to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from Indiana to Missouri that are best for you.

Fly from

Indiana

Fly to

Missouri

Route

Depart

Return

Price

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

Tue 2/24

6:10 am-7:35 am

Nonstop1h 25m

Lambert-St Louis

Tue 3/3

8:20 am-9:30 am

Nonstop1h 10m

$97

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

Tue 2/24

2:15 pm-8:35 pm

1 stop6h 20m

Lambert-St Louis

Tue 3/3

6:20 am-1:00 pm

1 stop6h 40m

$117

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

Tue 3/3

6:10 am-7:35 am

Nonstop1h 25m

Lambert-St Louis

Thu 3/5

2:15 pm-3:20 pm

Nonstop1h 05m

$134

IndianapolisKansas City

IND - MCI

INDMCI

Indianapolis

Sun 3/1

7:27 pm-9:53 am

1 stop15h 26m

Kansas City

Wed 3/4

4:39 pm-7:57 pm

1 stop26h 18m

$145

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

Tue 2/3

1:20 pm-6:51 am

1 stop17h 31m

Lambert-St Louis

Fri 2/6

8:22 pm-8:43 am

1 stop12h 21m

$154

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

Wed 2/18

1:45 pm-6:45 pm

1 stop5h 00m

Lambert-St Louis

Sat 2/21

5:30 am-1:00 pm

1 stop7h 30m

$154

CincinnatiKansas City

CVG - MCI

CVGMCI

Cincinnati Cinci./N. Kentucky

Thu 2/19

1:07 pm-10:03 am

1 stop21h 56m

Kansas City

Mon 2/23

10:55 am-5:32 pm

1 stop5h 37m

$157

CincinnatiSt. Louis

CVG - STL

CVGSTL

Cincinnati Cinci./N. Kentucky

Tue 3/3

3:20 pm-10:27 pm

1 stop8h 07m

Lambert-St Louis

Thu 3/5

3:49 pm-12:59 am

1 stop8h 10m

$163

IndianapolisKansas City

IND - MCI

INDMCI

Indianapolis

Thu 2/19

7:27 pm-10:03 am

1 stop15h 36m

Kansas City

Mon 2/23

10:55 am-6:31 pm

1 stop6h 36m

$166

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

Tue 2/17

10:34 pm-11:48 pm

Nonstop1h 14m

Lambert-St Louis

Thu 2/19

6:00 am-7:28 am

Nonstop1h 28m

$171

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 60 results
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Best time to book a flight from Indiana to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to Missouri

What is the cheapest month to book a flight from Indiana to Missouri?

Currently, September is the cheapest month in which you can book a flight from Indiana to Missouri (average of $75). Flying from Indiana to Missouri in May is currently the most expensive (average of $227). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IN to MO?

Find hourly flight availability from Indiana to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 27, 2026.

A simple way to save on the total cost of your ticket is to fly from Indiana to Missouri in the morning. If you’re flexible enough to do this you can expect to save up to 79% on your trip compared to booking a flight in the evening.

How much does it cost to fly round-trip from Indiana to Missouri?

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated January 27, 2026.
Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Indiana to Missouri. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,268 reviews

Food

7.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Overall

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,268 reviews
Southwest
8.0
Very good
4,268 reviews

Food

7.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Overall

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,118 reviews
Southwest
8.0
Very good
4,268 reviews

Food

7.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Overall

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,205 reviews
Southwest
8.0
Very good
4,268 reviews

Food

7.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Overall

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,197 reviews
Southwest
8.0
Very good
4,268 reviews

Food

7.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Overall

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Indiana to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Indiana to Missouri?

    Departing from Indiana to Missouri will take you 1h 14m. There are 258 mi between Indiana and Missouri. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Indiana to Missouri one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $440. Delta flights start at $460 while deals on WestJet start at $670 one-way.

  • Can I find deals for flights from Indiana to Missouri that include hotel bookings?

    Yes. In addition to deals on Indiana to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to Missouri.

  • Can I find deals for business class flights from Indiana to Missouri?

    Yes. Cheapflights offers flight deals from Indiana to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indiana to Missouri?

    Currently, September is the cheapest month in which you can book a flight from Indiana to Missouri (average of $75). Flying from Indiana to Missouri in May is currently the most expensive (average of $227). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Indiana to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Indiana to Missouri

Discover the top 4 airlines that operate flights from Indiana to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$178Average$331FlexibilityNo cancel feeOn-time71%
DeltaCheapest$198Average$297FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$213Average$368FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$221Average$334FlexibilityNo cancel feeOn-time63%

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