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$51+ Cheap flights from Indiana to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/24. Fares are subject to change and may not be available on all flights or dates of travel.
IND — STL
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Indiana to Missouri

Keep the following information in mind while searching for Indiana to Missouri flight deals. Data was last updated September 11, 2025.

Round-trip from

$101
(Southwest)

One-way from

$51
(Southwest)

Popular in

February

Cheapest in

September

Average price

$281

Good round-trip deal

$289 or less

Good one-way deal

$154 or less
From Indiana to Missouri
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One-way flight from Indiana to Missouri
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Highest demand for flights based on searches. 13% potential increase in price ($52 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Indiana to Missouri.
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Price to beat on a one-way flight from Indiana to Missouri.
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Find flight deals from Indiana to Missouri

Cheapest flights from Indiana to Missouri
Explore the most affordable flight options available from Indiana to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/511:25 amMDW - STL
Nonstop1h 10mSouthwest
Sat 11/86:25 amSTL - MDW
Nonstop1h 10mSouthwest
Deal found 9/11$101
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/19:25 amORD - STL
Nonstop1h 24mUnited Airlines
Sat 10/48:00 amSTL - ORD
Nonstop1h 30mUnited Airlines
Deal found 9/11$101
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/113:50 pmMDW - STL
Nonstop1h 10mSouthwest
Mon 10/135:40 amSTL - MDW
Nonstop1h 10mSouthwest
Deal found 9/9$117
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2110:34 pmORD - STL
Nonstop1h 20mAmerican Airlines
Fri 10/246:00 amSTL - ORD
Nonstop1h 23mAmerican Airlines
Deal found 9/10$117
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/48:00 amORD - STL
Nonstop1h 26mAmerican Airlines
Sun 10/56:05 amSTL - ORD
Nonstop1h 20mAmerican Airlines
Deal found 9/10$118
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/18:31 pmORD - STL
Nonstop1h 22mAmerican Airlines
Thu 10/26:05 amSTL - ORD
Nonstop1h 20mAmerican Airlines
Deal found 9/10$120
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/211:01 amORD - STL
Nonstop1h 27mUnited Airlines
Sun 10/59:20 amSTL - ORD
Nonstop1h 30mUnited Airlines
Deal found 9/11$133
This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/11:10 pmMDW - STL
Nonstop1h 15mSouthwest
Sat 10/45:55 pmSTL - MDW
Nonstop1h 10mSouthwest
Deal found 9/11$134
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/310:42 amORD - STL
1 stop22h 24mFrontier
Sat 10/47:55 pmSTL - ORD
1 stop13h 42mFrontier
Deal found 9/10$134
This eDestinos deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/17:20 amORD - STL
1 stop25h 46mFrontier
Thu 10/27:55 pmSTL - ORD
1 stop28h 04mFrontier
Deal found 9/10$139
This Priceline deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/256:20 amMDW - STL
1 stop8h 44mFrontier
Mon 9/294:00 pmSTL - MDW
1 stop7h 20mFrontier
Deal found 9/10$143
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/145:55 pmMDW - STL
Nonstop1h 15mSouthwest
Wed 10/155:05 pmSTL - MDW
Nonstop1h 05mSouthwest
Deal found 9/8$144

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indiana to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Indiana to Missouri that are best for you.

Fly from

Indiana

Fly to

Missouri

Route

Depart

Return

Price

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

Wed 11/5

2:23 pm-3:49 pm

Nonstop1h 26m

Lambert-St Louis

Sat 11/8

5:24 pm-6:47 pm

Nonstop1h 23m

$101

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

Wed 10/1

1:03 pm-2:27 pm

Nonstop1h 24m

Lambert-St Louis

Sat 10/4

5:28 pm-6:53 pm

Nonstop1h 25m

$101

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

Mon 11/3

6:20 am-7:35 am

Nonstop1h 15m

Lambert-St Louis

Wed 11/5

7:00 am-8:10 am

Nonstop1h 10m

$117

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

Wed 10/22

6:53 pm-8:26 pm

Nonstop1h 33m

Lambert-St Louis

Fri 10/24

6:00 am-7:23 am

Nonstop1h 23m

$117

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

Sat 10/11

1:03 pm-2:27 pm

Nonstop1h 24m

Lambert-St Louis

Mon 10/13

5:28 pm-6:53 pm

Nonstop1h 25m

$117

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

Fri 11/14

1:00 pm-2:25 pm

Nonstop1h 25m

Lambert-St Louis

Fri 11/14

6:43 pm-8:13 pm

Nonstop1h 30m

$133

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

Wed 10/1

1:10 pm-2:25 pm

Nonstop1h 15m

Lambert-St Louis

Sat 10/4

5:55 pm-7:05 pm

Nonstop1h 10m

$134

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

Thu 10/2

1:10 pm-4:35 pm

1 stop3h 25m

Lambert-St Louis

Fri 10/3

9:20 am-4:19 pm

1 stop6h 59m

$150

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

Fri 10/3

9:48 am-8:37 pm

1 stop10h 49m

Lambert-St Louis

Mon 10/6

4:00 pm-11:41 pm

1 stop7h 41m

$154

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

Thu 10/2

7:40 am-8:50 am

Nonstop1h 10m

Lambert-St Louis

Mon 10/6

6:30 pm-7:40 pm

Nonstop1h 10m

$157

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 60 results
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Best time to book a flight from Indiana to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to Missouri

What is the cheapest month to book a flight from Indiana to Missouri?

Currently, August is the cheapest month in which you can book a flight from Indiana to Missouri (average of $311). Flying from Indiana to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IN to MO?

Find hourly flight availability from Indiana to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Indiana to Missouri as you normally would.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated September 11, 2025.
Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Indiana to Missouri. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,248 reviews

Crew

8.6

Overall

8.0

Entertainment

7.5

Comfort

8.0

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,248 reviews
Southwest
8.0
Very good
4,248 reviews

Crew

8.6

Overall

8.0

Entertainment

7.5

Comfort

8.0

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,960 reviews
Southwest
8.0
Very good
4,248 reviews

Crew

8.6

Overall

8.0

Entertainment

7.5

Comfort

8.0

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
8,937 reviews
Southwest
8.0
Very good
4,248 reviews

Crew

8.6

Overall

8.0

Entertainment

7.5

Comfort

8.0

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,248 reviews

Crew

8.6

Overall

8.0

Entertainment

7.5

Comfort

8.0

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Indiana to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Indiana to Missouri?

    Departing from Indiana to Missouri will take you 1h 15m. There are 251 mi between Indiana and Missouri. Generally, flights for this route are nonstop.

  • What are the cheapest airlines to fly from Indiana to Missouri one-way?

    To fly one-way, consider booking your trip with Southwest, which is currently one of the cheapest options available, starting at $51. United Airlines flights start at $51 while deals on Delta start at $89 one-way.

  • Can I find deals for flights from Indiana to Missouri that include hotel bookings?

    Yes. In addition to deals on Indiana to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to Missouri.

  • Can I find deals for business class flights from Indiana to Missouri?

    Yes. Cheapflights offers flight deals from Indiana to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indiana to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Indiana to Missouri (average of $311). Flying from Indiana to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Indiana to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Indiana to Missouri

Discover the top 4 airlines that operate flights from Indiana to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$178Average$337FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$201Average$410FlexibilityNo cancel feeOn-time69%
DeltaCheapest$208Average$421FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$223Average$340FlexibilityNo cancel feeOn-time63%

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