$49+ Cheap flights from Indiana to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/28. Fares are subject to change and may not be available on all flights or dates of travel.
IND — STL
Apr 9 — Apr 161
Round-trip
1 adult, Economy
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Find cheap flights from Indiana to Missouri with Cheapflights
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Cheapest flights from Indiana to MissouriExplore the most affordable flight options available from Indiana to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.
Explore the most affordable flight options available from Indiana to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/912:20 pm
CVG
- STL
1 stop6h 14m
Frontier
Wed 4/158:23 pm
STL
- CVG
1 stop20h 10m
Frontier
Deal found 3/9![Frontier logo]()
$148
This Frontier deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/91:20 pm
CVG
- STL
1 stop11h 05m
Frontier
Fri 4/178:39 am
STL
- CVG
1 stop9h 44m
Frontier
Deal found 3/9![Frontier logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1011:51 am
CVG
- STL
1 stop22h 57m
Frontier
Wed 4/158:23 pm
STL
- CVG
1 stop20h 10m
Frontier
Deal found 3/9![Frontier logo]()
$182
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:50 pm
ORD
- COU
Nonstop1h 29m
American Airlines
Sun 4/510:08 am
COU
- ORD
Nonstop1h 29m
American Airlines
Deal found 3/9![American Airlines logo]()
$198
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/912:20 pm
CVG
- STL
1 stop6h 14m
Frontier
Thu 4/1611:25 am
STL
- CVG
1 stop5h 08m
Frontier
Deal found 3/9![Frontier logo]()
$199
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/135:43 pm
ORD
- COU
Nonstop1h 24m
American Airlines
Mon 11/161:53 pm
COU
- ORD
Nonstop1h 37m
American Airlines
Deal found 3/6![American Airlines logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/912:20 pm
CVG
- STL
1 stop6h 14m
Frontier
Sat 4/188:17 pm
STL
- CVG
1 stop21h 55m
Frontier
Deal found 3/9![Frontier logo]()
$200
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/77:20 am
CVG
- STL
1 stop27h 28m
Frontier
Wed 4/158:23 pm
STL
- CVG
1 stop20h 10m
Frontier
Deal found 3/9![Frontier logo]()
$207
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/24:45 pm
ORD
- SGF
Nonstop1h 54m
United Airlines
Wed 5/66:22 pm
SGF
- ORD
Nonstop1h 43m
United Airlines
Deal found 3/9![United Airlines logo]()
$209
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/23:43 pm
ORD
- SGF
Nonstop1h 47m
American Airlines
Sun 4/57:36 am
SGF
- ORD
Nonstop1h 51m
American Airlines
Deal found 3/8![American Airlines logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/177:46 pm
CVG
- STL
1 stop12h 04m
Frontier
Mon 4/208:23 pm
STL
- CVG
2 stops25h 57m
Frontier
Deal found 3/9![Frontier logo]()
$212
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2712:40 pm
ORD
- COU
Nonstop1h 26m
United Airlines
Mon 3/308:00 am
COU
- ORD
Nonstop1h 30m
United Airlines
Deal found 3/7![United Airlines logo]()
$214
Best flights from Indiana to MissouriDiscover carefully curated flight deals from Indiana to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 10, 2026.
Discover carefully curated flight deals from Indiana to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 10, 2026.
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/149:16 am
ORD
- COU
Nonstop1h 39m
United Airlines
Mon 8/1711:30 am
COU
- ORD
Nonstop1h 43m
United Airlines
Deal found 3/8![United Airlines logo]()
$199
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/278:05 am
ORD
- COU
Nonstop1h 28m
American Airlines
Mon 3/3010:08 am
COU
- ORD
Nonstop1h 29m
American Airlines
Deal found 3/7![American Airlines logo]()
$214
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/142:25 pm
ORD
- SGF
1 stop6h 42m
Delta
Tue 4/213:59 pm
SGF
- ORD
1 stop6h 22m
Delta
Deal found 3/8![Delta logo]()
$229
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/99:00 am
MDW
- STL
Nonstop1h 15m
Southwest
Wed 6/245:55 pm
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 3/9![Southwest logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:44 pm
CVG
- STL
1 stop13h 06m
Frontier
Sun 4/264:59 pm
STL
- CVG
2 stops24h 37m
Frontier
Deal found 3/7![Frontier logo]()
$246
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/134:10 pm
ORD
- COU
Nonstop1h 35m
United Airlines
Sun 8/163:05 pm
COU
- ORD
Nonstop1h 43m
United Airlines
Deal found 3/9![United Airlines logo]()
$199
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/267:58 pm
ORD
- COU
Nonstop1h 35m
United Airlines
Mon 3/308:00 am
COU
- ORD
Nonstop1h 30m
United Airlines
Deal found 3/5![United Airlines logo]()
$199
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/237:56 pm
ORD
- COU
Nonstop1h 34m
American Airlines
Sun 4/266:00 am
COU
- ORD
Nonstop1h 43m
American Airlines
Deal found 3/10![American Airlines logo]()
$219
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/309:16 am
MDW
- SGF
1 stop24h 10m
Multiple Airlines
Sun 5/31:19 pm
SGF
- MDW
1 stop25h 45m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$447
This Delta deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/89:40 am
ORD
- SGF
1 stop5h 30m
Delta
Mon 4/136:55 pm
SGF
- ORD
1 stop5h 04m
Delta
Deal found 3/7![Delta logo]()
$229
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/310:50 pm
ORD
- COU
Nonstop1h 43m
United Airlines
Mon 4/65:00 am
COU
- ORD
Nonstop1h 30m
United Airlines
Deal found 3/6![United Airlines logo]()
$199
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/89:45 pm
MDW
- MCI
Nonstop1h 30m
Southwest
Wed 6/102:30 pm
MCI
- MDW
Nonstop1h 25m
Southwest
Deal found 3/6![Southwest logo]()
$245
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/29:20 am
ORD
- COU
1 stop7h 47m
American Airlines
Sun 4/510:08 am
COU
- ORD
Nonstop1h 29m
American Airlines
Deal found 3/9![American Airlines logo]()
$223
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1412:52 pm
MDW
- SGF
1 stop5h 20m
Delta
Tue 4/213:59 pm
SGF
- MDW
1 stop6h 29m
Delta
Deal found 3/8![Delta logo]()
$229
This Southwest deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/222:35 pm
MDW
- STL
1 stop5h 25m
Southwest
Wed 4/291:15 pm
STL
- MDW
2 stops6h 20m
Southwest
Deal found 3/8![Southwest logo]()
$245
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:00 am
MDW
- SGF
1 stop5h 01m
Delta
Sat 5/24:00 pm
SGF
- MDW
1 stop6h 28m
Delta
Deal found 3/8![Delta logo]()
$229
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/98:55 am
ORD
- SGF
Nonstop1h 53m
United Airlines
Thu 4/166:50 pm
SGF
- ORD
Nonstop1h 48m
United Airlines
Deal found 3/6![United Airlines logo]()
$209
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/148:55 am
ORD
- SGF
Nonstop1h 53m
United Airlines
Tue 4/216:50 pm
SGF
- ORD
Nonstop1h 48m
United Airlines
Deal found 3/8![United Airlines logo]()
$209
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/93:26 pm
ORD
- SGF
1 stop6h 28m
American Airlines
Thu 4/166:05 pm
SGF
- ORD
Nonstop1h 59m
American Airlines
Deal found 3/10![American Airlines logo]()
$254
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/273:45 pm
ORD
- MCI
1 stop7h 40m
Southwest
Tue 4/285:30 am
MCI
- ORD
1 stop5h 40m
Southwest
Deal found 3/9![Southwest logo]()
$258
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/301:15 pm
ORD
- SGF
1 stop4h 55m
Delta
Sun 8/26:45 pm
SGF
- ORD
1 stop5h 10m
Delta
Deal found 3/6![Delta logo]()
$244
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/78:09 pm
ORD
- SGF
Nonstop1h 55m
United Airlines
Tue 4/146:50 pm
SGF
- ORD
Nonstop1h 48m
United Airlines
Deal found 3/8![United Airlines logo]()
$209
This Expedia deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/1311:58 am
CVG
- STL
1 stop22h 51m
Frontier
Sun 3/159:05 pm
STL
- CVG
1 stop26h 14m
Frontier
Deal found 3/9![Frontier logo]()
$340
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/279:55 pm
MDW
- STL
Nonstop1h 15m
Southwest
Sat 3/288:25 am
STL
- MDW
1 stop3h 30m
Southwest
Deal found 3/6![Southwest logo]()
$265
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/204:30 pm
ORD
- COU
Nonstop1h 30m
American Airlines
Tue 3/245:49 pm
COU
- ORD
1 stop5h 47m
American Airlines
Deal found 3/8![American Airlines logo]()
$269
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/278:15 am
ORD
- SGF
1 stop6h 30m
Delta
Sun 8/306:00 am
SGF
- ORD
1 stop6h 08m
Delta
Deal found 3/10![Delta logo]()
$249
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/298:04 pm
ORD
- SGF
Nonstop1h 55m
United Airlines
Sat 4/46:50 pm
SGF
- ORD
Nonstop1h 48m
United Airlines
Deal found 3/8![United Airlines logo]()
$209
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:00 am
ORD
- MCI
1 stop8h 10m
Southwest
Tue 5/265:30 am
MCI
- ORD
1 stop5h 40m
Southwest
Deal found 3/9![Southwest logo]()
$268
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/710:45 am
MDW
- SGF
1 stop7h 26m
Delta
Tue 4/143:59 pm
SGF
- MDW
1 stop6h 29m
Delta
Deal found 3/10![Delta logo]()
$249
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2712:40 pm
ORD
- COU
Nonstop1h 26m
United Airlines
Mon 3/308:00 am
COU
- ORD
Nonstop1h 30m
United Airlines
Deal found 3/7![United Airlines logo]()
$214
Last-minute flights from Indiana to MissouriDiscover last-minute flight deals from Indiana to Missouri. Data last updated March 10, 2026 and is based on user searches.
Discover last-minute flight deals from Indiana to Missouri. Data last updated March 10, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2712:40 pm
ORD
- COU
Nonstop1h 26m
United Airlines
Mon 3/308:00 am
COU
- ORD
Nonstop1h 30m
United Airlines
Deal found 3/7![United Airlines logo]()
$214
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:50 pm
ORD
- COU
Nonstop1h 29m
American Airlines
Sun 4/510:08 am
COU
- ORD
Nonstop1h 29m
American Airlines
Deal found 3/9![American Airlines logo]()
$198
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/23:43 pm
ORD
- SGF
Nonstop1h 47m
American Airlines
Sun 4/57:36 am
SGF
- ORD
Nonstop1h 51m
American Airlines
Deal found 3/8![American Airlines logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/77:20 am
CVG
- STL
1 stop27h 28m
Frontier
Wed 4/158:23 pm
STL
- CVG
1 stop20h 10m
Frontier
Deal found 3/9![Frontier logo]()
$207
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/912:20 pm
CVG
- STL
1 stop6h 14m
Frontier
Wed 4/158:23 pm
STL
- CVG
1 stop20h 10m
Frontier
Deal found 3/9![Frontier logo]()
$148
This Frontier deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/91:20 pm
CVG
- STL
1 stop11h 05m
Frontier
Fri 4/178:39 am
STL
- CVG
1 stop9h 44m
Frontier
Deal found 3/9![Frontier logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/912:20 pm
CVG
- STL
1 stop6h 14m
Frontier
Thu 4/1611:25 am
STL
- CVG
1 stop5h 08m
Frontier
Deal found 3/9![Frontier logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/912:20 pm
CVG
- STL
1 stop6h 14m
Frontier
Sat 4/188:17 pm
STL
- CVG
1 stop21h 55m
Frontier
Deal found 3/9![Frontier logo]()
$200
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1011:51 am
CVG
- STL
1 stop22h 57m
Frontier
Wed 4/158:23 pm
STL
- CVG
1 stop20h 10m
Frontier
Deal found 3/9![Frontier logo]()
$182
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1010:50 pm
ORD
- COU
Nonstop1h 43m
United Airlines
Mon 4/135:00 am
COU
- ORD
Nonstop1h 30m
United Airlines
Deal found 3/6![United Airlines logo]()
$199
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/148:55 am
ORD
- SGF
Nonstop1h 53m
United Airlines
Sat 4/188:00 am
SGF
- ORD
Nonstop1h 47m
United Airlines
Deal found 3/6![United Airlines logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/177:46 pm
CVG
- STL
1 stop12h 04m
Frontier
Mon 4/208:23 pm
STL
- CVG
2 stops25h 57m
Frontier
Deal found 3/9![Frontier logo]()
$212
One-way flights from Indiana to MissouriSearch for one-way flight options from Indiana to Missouri. Find affordable one-way fares based on user searches. Data last updated March 10, 2026.
Search for one-way flight options from Indiana to Missouri. Find affordable one-way fares based on user searches. Data last updated March 10, 2026.
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2810:15 am
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 3/10![Southwest logo]()
$49
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/317:40 pm
ORD
- STL
Nonstop1h 28m
United Airlines
Deal found 3/9![United Airlines logo]()
$49
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/141:25 pm
MDW
- STL
1 stop6h 30m
Southwest
Deal found 3/10![Southwest logo]()
$59
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/142:40 pm
ORD
- STL
1 stop4h 35m
Southwest
Deal found 3/10![Southwest logo]()
$59
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/292:40 pm
ORD
- STL
1 stop7h 20m
Southwest
Deal found 3/10![Southwest logo]()
$64
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/142:15 pm
MDW
- STL
1 stop16h 35m
Frontier
Deal found 3/6![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:00 am
MDW
- STL
1 stop24h 50m
Frontier
Deal found 3/6![Frontier logo]()
$66
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3110:30 pm
ORD
- STL
Nonstop1h 14m
American Airlines
Deal found 3/10![American Airlines logo]()
$66
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/62:56 pm
MDW
- STL
1 stop19h 34m
Frontier
Deal found 3/6![Frontier logo]()
$67
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:53 pm
CVG
- STL
1 stop12h 57m
Frontier
Deal found 3/6![Frontier logo]()
$70
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:00 am
MDW
- STL
1 stop24h 50m
Frontier
Deal found 3/10![Frontier logo]()
$70
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/54:28 pm
ORD
- STL
1 stop14h 22m
Frontier
Deal found 3/7![Frontier logo]()
$70
Find flight deals from Indiana to Missouri
Keep the following information in mind while searching for Indiana to Missouri flight deals. Data was last updated March 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $148 (Kiwi.com) |
One-way from | $49 (Southwest) |
Popular in | September |
Cheapest in | November |
Average price | $282 |
Good round-trip deal | $428 or less |
Good one-way deal | $185 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Indiana to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
Use the filters below to find and compare flights from Indiana to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Fri 8/14
9:16 am-10:55 am
Nonstop1h 39m
Columbia Regional
Mon 8/17
11:30 am-1:13 pm
Nonstop1h 43m
$199
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Thu 8/13
4:10 pm-5:45 pm
Nonstop1h 35m
Columbia Regional
Sun 8/16
3:05 pm-4:48 pm
Nonstop1h 43m
$199
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Thu 3/26
7:58 pm-9:33 pm
Nonstop1h 35m
Columbia Regional
Mon 3/30
8:00 am-9:30 am
Nonstop1h 30m
$199
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Fri 4/3
10:50 pm-12:33 am
Nonstop1h 43m
Columbia Regional
Mon 4/6
5:00 am-6:30 am
Nonstop1h 30m
$199
ChicagoSpringfield
ORD - SGF
ORDSGF
Chicago O'Hare Intl
Thu 4/9
8:55 am-10:48 am
Nonstop1h 53m
Springfield-Branson
Thu 4/16
6:50 pm-8:38 pm
Nonstop1h 48m
$209
ChicagoSpringfield
ORD - SGF
ORDSGF
Chicago O'Hare Intl
Tue 4/14
8:55 am-10:48 am
Nonstop1h 53m
Springfield-Branson
Tue 4/21
6:50 pm-8:38 pm
Nonstop1h 48m
$209
ChicagoSpringfield
ORD - SGF
ORDSGF
Chicago O'Hare Intl
Tue 4/7
8:09 pm-10:04 pm
Nonstop1h 55m
Springfield-Branson
Tue 4/14
6:50 pm-8:38 pm
Nonstop1h 48m
$209
ChicagoSpringfield
ORD - SGF
ORDSGF
Chicago O'Hare Intl
Sun 3/29
8:04 pm-9:59 pm
Nonstop1h 55m
Springfield-Branson
Sat 4/4
6:50 pm-8:38 pm
Nonstop1h 48m
$209
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Fri 3/27
8:05 am-9:33 am
Nonstop1h 28m
Columbia Regional
Mon 3/30
10:08 am-11:37 am
Nonstop1h 29m
$214
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Fri 3/27
12:40 pm-2:06 pm
Nonstop1h 26m
Columbia Regional
Mon 3/30
8:00 am-9:30 am
Nonstop1h 30m
$214
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Indiana to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Indiana with our price prediction graph.
ORD-COU
ORD-SGF
MDW-STL
CVG-STL
MDW-SGF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Indiana to Missouri
USIN-USMO
ORD-COU
ORD-SGF
MDW-STL
CVG-STL
What is the cheapest month to book a flight from Indiana to Missouri?
Currently, September is the cheapest month in which you can book a flight from Indiana to Missouri (average of $75). Flying from Indiana to Missouri in March is currently the most expensive (average of $239). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from IN to MO?
Find hourly flight availability from Indiana to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 10, 2026.
A simple way to save on the total cost of your ticket is to fly from Indiana to Missouri in the morning. If you’re flexible enough to do this you can expect to save up to 79% on your trip compared to booking a flight in the evening.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated March 10, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Indiana to Missouri. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Entertainment
7.5
Food
7.0
Overall
8.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Crew
8.6
Entertainment
7.5
Food
7.0
Overall
8.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Crew
8.6
Entertainment
7.5
Food
7.0
Overall
8.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Crew
8.6
Entertainment
7.5
Food
7.0
Overall
8.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Crew
8.6
Entertainment
7.5
Food
7.0
Overall
8.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Related info for your journey
Find useful and relevant information for your journey from Indiana to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Indiana to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Indiana to Missouri by cabin class
Find flights from Indiana to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Indiana and Missouri flights
Browse other Indiana and Missouri flight options. Last updated on March 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Indiana after your stay in Missouri
Indiana to Missouri flights
Consider these flights traveling from Indiana to Missouri.
Top 4 airlines flying from Indiana to Missouri
Discover the top 4 airlines that operate flights from Indiana to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$178 | Average$334 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$198 | Average$322 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$221 | Average$332 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$228 | Average$353 | FlexibilityNo cancel fee | On-time69% |