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$61+ Cheap flights from Indiana to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/9. Fares are subject to change and may not be available on all flights or dates of travel.
IND — STL
Feb 5 — Feb 121
Thu 2/5
Thu 2/12
1 adult, Economy
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Cheap flight deals from Indiana to Missouri

Keep the following information in mind while searching for Indiana to Missouri flight deals. Data was last updated January 6, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$129
(Frontier)

One-way from

$61
(Trip.com)

Popular in

September

Cheapest in

November

Average price

$386

Good round-trip deal

$391 or less

Good one-way deal

$264 or less
Provider with most accurate pricing for Indianapolis-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Indianapolis-Lambert-St Louis flights.
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From Indiana to Missouri
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One-way flight from Indiana to Missouri
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Highest demand for flights based on searches. 8% potential increase in price ($35 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($17 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Price to beat on a round-trip flight from Indiana to Missouri.
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Price to beat on a one-way flight from Indiana to Missouri.
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Find flight deals from Indiana to Missouri

Cheapest flights from Indiana to Missouri
Explore the most affordable flight options available from Indiana to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 6, 2026.

This Frontier deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/319:00 amCVG - STL
1 stop24h 24mFrontier
Sat 2/712:12 pmSTL - CVG
1 stop9h 08mFrontier
Deal found 1/5$129
This Kiwi.com deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/274:23 pmCVG - STL
1 stop8h 10mFrontier
Wed 1/285:42 pmSTL - CVG
1 stop28h 44mFrontier
Deal found 1/5$143
This Kiwi.com deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/312:44 pmORD - STL
1 stop10h 49mMultiple Airlines
Mon 2/95:42 pmSTL - ORD
1 stop22h 10mMultiple Airlines
Deal found 1/4$152
This Southwest deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/281:15 pmMDW - MCI
Nonstop1h 30mSouthwest
Wed 1/285:25 pmMCI - MDW
Nonstop1h 25mSouthwest
Deal found 1/6$157
This Frontier deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/225:39 pmCVG - STL
1 stop6h 54mFrontier
Mon 1/2610:16 amSTL - CVG
1 stop12h 10mFrontier
Deal found 1/5$160
This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/3011:45 amORD - STL
1 stop11h 48mMultiple Airlines
Mon 2/25:42 pmSTL - ORD
1 stop28h 02mMultiple Airlines
Deal found 1/6$160
This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/2911:51 amORD - STL
1 stop11h 42mMultiple Airlines
Mon 2/25:42 pmSTL - ORD
1 stop28h 02mMultiple Airlines
Deal found 1/6$161
This Delta deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/2910:48 amMDW - MCI
1 stop6h 25mDelta
Mon 2/26:15 amMCI - MDW
1 stop6h 51mDelta
Deal found 1/6$163
This Kiwi.com deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/2911:51 amORD - STL
1 stop11h 42mMultiple Airlines
Fri 1/305:42 pmSTL - ORD
1 stop24h 10mMultiple Airlines
Deal found 1/5$169
This Kiwi.com deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/198:52 pmIND - MCI
1 stop21h 36mMultiple Airlines
Mon 2/2311:26 amMCI - IND
1 stop10h 22mMultiple Airlines
Deal found 1/4$175
This Kiwi.com deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/24:38 pmORD - STL
2 stops30h 55mMultiple Airlines
Mon 2/95:42 pmSTL - ORD
1 stop22h 10mMultiple Airlines
Deal found 1/5$176
This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/221:22 pmCVG - STL
1 stop18h 29mFrontier
Sun 1/255:42 pmSTL - CVG
1 stop28h 44mFrontier
Deal found 1/6$177

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indiana to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 6, 2026.
Use the filters below to find and compare flights from Indiana to Missouri that are best for you.

Fly from

Indiana

Fly to

Missouri

Route

Depart

Return

Price

CincinnatiSt. Louis

CVG - STL

CVGSTL

Cincinnati Cinci./N. Kentucky

Thu 1/22

5:39 pm-11:33 pm

1 stop6h 54m

Lambert-St Louis

Mon 1/26

10:16 am-11:26 pm

1 stop12h 10m

$160

IndianapolisKansas City

IND - MCI

INDMCI

Indianapolis

Thu 2/19

8:52 pm-5:28 pm

1 stop21h 36m

Kansas City

Mon 2/23

11:26 am-10:48 pm

1 stop10h 22m

$175

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

Tue 2/3

1:00 pm-2:30 pm

Nonstop1h 30m

Lambert-St Louis

Tue 2/10

9:57 am-11:32 am

Nonstop1h 35m

$179

CincinnatiSt. Louis

CVG - STL

CVGSTL

Cincinnati Cinci./N. Kentucky

Sat 1/17

2:27 pm-10:34 pm

1 stop9h 07m

Lambert-St Louis

Sat 1/24

12:12 pm-10:20 pm

1 stop9h 08m

$181

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

Tue 2/3

1:20 pm-6:51 am

1 stop17h 31m

Lambert-St Louis

Thu 2/5

10:01 pm-3:58 pm

2 stops17h 57m

$186

CincinnatiSt. Louis

CVG - STL

CVGSTL

Cincinnati Cinci./N. Kentucky

Wed 1/21

4:23 pm-11:33 pm

1 stop8h 10m

Lambert-St Louis

Sun 1/25

5:42 pm-1:00 pm

1 stop18h 18m

$186

ChicagoSpringfield

ORD - SGF

ORDSGF

Chicago O'Hare Intl

Sat 2/14

3:43 pm-5:30 pm

Nonstop1h 47m

Springfield-Branson

Sun 2/15

7:34 am-9:25 am

Nonstop1h 51m

$189

CincinnatiSt. Louis

CVG - STL

CVGSTL

Cincinnati Cinci./N. Kentucky

Tue 1/27

4:23 pm-11:33 pm

1 stop8h 10m

Lambert-St Louis

Wed 1/28

5:42 pm-1:03 pm

2 stops18h 21m

$191

CincinnatiSt. Louis

CVG - STL

CVGSTL

Cincinnati Cinci./N. Kentucky

Tue 1/27

4:23 pm-11:33 pm

1 stop8h 10m

Lambert-St Louis

Sun 2/1

5:42 pm-8:53 pm

2 stops26h 11m

$193

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

Tue 2/3

9:53 am-4:45 pm

1 stop6h 52m

Lambert-St Louis

Tue 2/10

6:35 am-12:46 pm

1 stop6h 11m

$199

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/6

Showing 1-10 of 60 results
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Best time to book a flight from Indiana to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to Missouri

What is the cheapest month to book a flight from Indiana to Missouri?

Currently, September is the cheapest month in which you can book a flight from Indiana to Missouri (average of $75). Flying from Indiana to Missouri in May is currently the most expensive (average of $227). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IN to MO?

Find hourly flight availability from Indiana to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 6, 2026.

A simple way to save on the total cost of your ticket is to fly from Indiana to Missouri in the morning. If you’re flexible enough to do this you can expect to save up to 80% on your trip compared to booking a flight in the evening.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated January 6, 2026.
Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Indiana to Missouri. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,248 reviews

Boarding

8.1

Overall

8.0

Comfort

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,248 reviews
Southwest
8.0
Very good
4,248 reviews

Boarding

8.1

Overall

8.0

Comfort

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,018 reviews
Southwest
8.0
Very good
4,248 reviews

Boarding

8.1

Overall

8.0

Comfort

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,132 reviews
Southwest
8.0
Very good
4,248 reviews

Boarding

8.1

Overall

8.0

Comfort

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,084 reviews
Southwest
8.0
Very good
4,248 reviews

Boarding

8.1

Overall

8.0

Comfort

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Indiana to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Indiana to Missouri?

    Departing from Indiana to Missouri will take you 1h 30m. There are 258 mi between Indiana and Missouri. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Indiana to Missouri one-way?

    To fly one-way, consider booking your trip with United Airlines, which is currently one of the cheapest options available, starting at $94. American Airlines flights start at $98 while deals on Delta start at $100 one-way.

  • Can I find deals for flights from Indiana to Missouri that include hotel bookings?

    Yes. In addition to deals on Indiana to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to Missouri.

  • Can I find deals for business class flights from Indiana to Missouri?

    Yes. Cheapflights offers flight deals from Indiana to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indiana to Missouri?

    Currently, September is the cheapest month in which you can book a flight from Indiana to Missouri (average of $75). Flying from Indiana to Missouri in May is currently the most expensive (average of $227). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Indiana to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Indiana to Missouri

Discover the top 4 airlines that operate flights from Indiana to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 6, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$178Average$334FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$213Average$358FlexibilityNo cancel feeOn-time69%
DeltaCheapest$216Average$318FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$221Average$332FlexibilityNo cancel feeOn-time63%

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