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$158+ Cheap flights from Harrisburg (MDT) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/20. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — STL
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Harrisburg to Missouri

Keep the following information in mind while searching for Harrisburg to Missouri flight deals. Data was last updated September 11, 2025.

Round-trip from

$249
(American Airlines)

One-way from

$158
(Kiwi.com)

Popular in

April

Cheapest in

August

Average price

$340
From Harrisburg to Missouri
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One-way flight from Harrisburg to Missouri
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Highest demand for flights based on searches. 14% potential increase in price ($63 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($15 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Harrisburg to Missouri

Cheapest flights from Harrisburg to Missouri
Explore the most affordable flight options available from Harrisburg to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/255:00 amMDT - MCI
1 stop7h 13mAmerican Airlines
Wed 12/316:36 pmMCI - MDT
1 stop4h 43mAmerican Airlines
Deal found 9/9$199
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/126:48 amMDT - STL
1 stop8h 32mAmerican Airlines
Mon 11/175:56 pmSTL - MDT
1 stop4h 57mAmerican Airlines
Deal found 9/10$249
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/156:00 amMDT - MCI
1 stop6h 31mDelta
Tue 10/215:51 pmMCI - MDT
1 stop4h 09mDelta
Deal found 9/10$259
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/246:00 amMDT - STL
1 stop7h 21mDelta
Sun 9/286:01 amSTL - MDT
1 stop3h 57mDelta
Deal found 9/9$259
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/296:00 amMDT - MCI
2 stops8h 00mAmerican Airlines
Sat 11/13:31 pmMCI - MDT
1 stop7h 17mAmerican Airlines
Deal found 9/11$264
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/46:15 amMDT - SGF
2 stops8h 45mUnited Airlines
Tue 10/73:11 pmSGF - MDT
1 stop5h 14mUnited Airlines
Deal found 9/9$264
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/246:25 pmMDT - MCI
1 stop6h 27mDelta
Sun 10/266:15 amMCI - MDT
1 stop4h 38mDelta
Deal found 9/10$274
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/34:45 pmMDT - SGF
1 stop4h 58mAmerican Airlines
Tue 10/74:18 pmSGF - MDT
1 stop5h 55mAmerican Airlines
Deal found 9/9$274
This Frontier deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2210:57 amMDT - STL
2 stops23h 09mFrontier
Thu 9/2510:49 amSTL - MDT
2 stops22h 23mFrontier
Deal found 9/10$276
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/138:15 amMDT - MCI
1 stop7h 06mUnited Airlines
Sat 11/156:00 amMCI - MDT
2 stops6h 58mUnited Airlines
Deal found 9/9$279
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/306:15 amMDT - SGF
2 stops9h 24mUnited Airlines
Sun 11/211:26 amSGF - MDT
1 stop6h 49mUnited Airlines
Deal found 9/10$279
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/128:15 amMDT - MCI
2 stops8h 50mUnited Airlines
Tue 11/186:00 amMCI - MDT
2 stops6h 58mUnited Airlines
Deal found 9/9$284

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Harrisburg to Missouri that are best for you.

Fly from

Harrisburg

Fly to

Missouri

Route

Depart

Return

Price

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

Wed 11/12

7:04 pm-11:07 pm

1 stop5h 03m

Lambert-St Louis

Mon 11/17

5:56 pm-11:53 pm

1 stop4h 57m

$249

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

Mon 10/6

6:25 pm-11:41 pm

1 stop6h 16m

Lambert-St Louis

Sat 10/11

5:22 pm-11:00 pm

1 stop4h 38m

$249

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

Tue 10/7

6:25 pm-10:04 pm

1 stop4h 39m

Lambert-St Louis

Sat 10/11

3:59 pm-11:08 pm

1 stop6h 09m

$249

HarrisburgKansas City

MDT - MCI

MDTMCI

Harrisburg

Thu 11/13

6:20 am-12:50 pm

1 stop7h 30m

Kansas City

Sat 11/15

3:47 pm-11:36 pm

1 stop6h 49m

$259

HarrisburgKansas City

MDT - MCI

MDTMCI

Harrisburg

Tue 10/14

6:25 pm-11:52 pm

1 stop6h 27m

Kansas City

Wed 10/22

5:39 pm-11:08 pm

1 stop4h 29m

$259

HarrisburgKansas City

MDT - MCI

MDTMCI

Harrisburg

Wed 11/5

6:00 am-11:31 am

1 stop6h 31m

Kansas City

Sat 11/8

5:51 pm-11:00 pm

1 stop4h 09m

$259

HarrisburgKansas City

MDT - MCI

MDTMCI

Harrisburg

Wed 10/15

6:00 am-11:31 am

1 stop6h 31m

Kansas City

Wed 10/22

4:39 pm-11:08 pm

1 stop5h 29m

$259

HarrisburgKansas City

MDT - MCI

MDTMCI

Harrisburg

Tue 10/14

6:00 am-12:29 pm

1 stop7h 29m

Kansas City

Tue 10/21

5:51 pm-11:00 pm

1 stop4h 09m

$259

HarrisburgKansas City

MDT - MCI

MDTMCI

Harrisburg

Wed 10/15

6:00 am-11:31 am

1 stop6h 31m

Kansas City

Tue 10/21

5:51 pm-11:00 pm

1 stop4h 09m

$259

HarrisburgKansas City

MDT - MCI

MDTMCI

Harrisburg

Wed 10/29

6:25 pm-11:52 pm

1 stop6h 27m

Kansas City

Sat 11/1

6:15 am-11:40 am

1 stop4h 25m

$259

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 50 results
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Best time to book a flight from Harrisburg to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Missouri

What is the cheapest month to book a flight from Harrisburg to Missouri?

Currently, August is the cheapest month in which you can book a flight from Harrisburg to Missouri (average of $311). Flying from Harrisburg to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDT to MO?

Find hourly flight availability from Harrisburg to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Harrisburg to Missouri as you normally would.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated September 11, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Harrisburg to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,937 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Harrisburg to Missouri?

    Harrisburg (MDT) is the airport you will fly out of if you book a flight from Harrisburg to Missouri. It is only a 8.5 mi journey to Harrisburg (MDT) from Harrisburg’s city center.

  • How long is the flight from Harrisburg to Missouri?

    Airlines like American Airlines, Delta, and United Airlines fly from Harrisburg to Missouri in about 5h 03m. The time it takes to get you to your destination can typically vary by up to 3h 42m. Airlines will cover a distance of 731 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Harrisburg to Missouri one-way?

    To fly one-way, consider booking your trip with Allegiant Air, which is currently one of the cheapest options available, starting at $235. American Airlines flights start at $240 while deals on Delta start at $271 one-way.

  • What are the most popular routes from Harrisburg to Missouri?

    When deciding which route to take from Harrisburg to Missouri consider Harrisburg - Lambert-St Louis, Harrisburg - Kansas City or Harrisburg - Springfield-Branson as they are the most popular.

  • Can I find deals for flights from Harrisburg to Missouri that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Missouri.

  • Can I find deals for business class flights from Harrisburg to Missouri?

    Yes. Cheapflights offers flight deals from Harrisburg to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Harrisburg to Missouri (average of $311). Flying from Harrisburg to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Harrisburg to Missouri

Discover the top 3 airlines that operate flights from Harrisburg to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$219Average$323FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$248Average$463FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$248Average$373FlexibilityNo cancel feeOn-time71%

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