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Missouri

$135+ Cheap flights from Harrisburg (MDT) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/19. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — STL
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Harrisburg to Missouri

Cheapest flights from Harrisburg to Missouri
Explore the most affordable flight options available from Harrisburg to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/295:09 amMDT - STL
1 stop4h 26mAmerican Airlines
Fri 1/24:53 pmSTL - MDT
1 stop6h 06mAmerican Airlines
Deal found 12/10$269
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/213:00 pmMDT - MCI
1 stop6h 31mUnited Airlines
Wed 12/243:19 pmMCI - MDT
1 stop7h 48mUnited Airlines
Deal found 12/11$288
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:15 amMDT - SGF
2 stops11h 05mUnited Airlines
Sun 12/286:20 pmSGF - MDT
1 stop4h 47mUnited Airlines
Deal found 12/10$314
This United Airlines deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:15 amMDT - SGF
2 stops11h 05mUnited Airlines
Sat 12/276:20 pmSGF - MDT
1 stop4h 47mUnited Airlines
Deal found 12/8$344
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:30 amMDT - SGF
1 stop5h 19mUnited Airlines
Sat 12/276:20 pmSGF - MDT
1 stop4h 47mUnited Airlines
Deal found 12/11$363
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/286:30 amMDT - STL
1 stop6h 57mUnited Airlines
Mon 1/56:35 pmSTL - MDT
1 stop4h 32mUnited Airlines
Deal found 12/10$376
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/285:00 amMDT - STL
1 stop4h 35mAmerican Airlines
Mon 1/52:04 pmSTL - MDT
1 stop5h 17mAmerican Airlines
Deal found 12/10$379
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/196:30 amMDT - MCI
2 stops10h 37mUnited Airlines
Tue 12/236:35 pmMCI - MDT
1 stop4h 32mUnited Airlines
Deal found 12/11$391
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:15 amMDT - JLN
2 stops10h 54mUnited Airlines
Sun 1/47:50 amJLN - MDT
1 stop5h 18mUnited Airlines
Deal found 12/10$400
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/198:00 pmMDT - MCI
1 stop6h 38mAmerican Airlines
Tue 12/235:12 amMCI - MDT
1 stop5h 00mAmerican Airlines
Deal found 12/11$409
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:15 amMDT - SGF
2 stops11h 05mUnited Airlines
Mon 12/296:20 pmSGF - MDT
1 stop4h 47mUnited Airlines
Deal found 12/10$422
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/263:00 pmMDT - STL
1 stop5h 22mUnited Airlines
Tue 12/306:35 pmSTL - MDT
1 stop4h 32mUnited Airlines
Deal found 12/11$424

Find flight deals from Harrisburg to Missouri

Keep the following information in mind while searching for Harrisburg to Missouri flight deals. Data was last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$222
(United Airlines)

One-way from

$135
(American Airlines)

Popular in

November

Cheapest in

April

Average price

$398
Provider with most accurate pricing for Harrisburg-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Harrisburg-Lambert-St Louis flights.
Search Deals
From Harrisburg to Missouri
Search Deals
One-way flight from Harrisburg to Missouri
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($27 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Harrisburg to Missouri that are best for you.

Fly from

Harrisburg

Fly to

Missouri

Route

Depart

Return

Price

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

Tue 3/10

6:00 am-9:46 am

1 stop4h 46m

Lambert-St Louis

Tue 3/17

5:00 pm-11:47 pm

1 stop5h 47m

$251

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

Tue 3/10

8:00 am-2:53 pm

2 stops7h 53m

Lambert-St Louis

Tue 3/17

6:33 pm-11:49 pm

1 stop4h 16m

$256

HarrisburgKansas City

MDT - MCI

MDTMCI

Harrisburg

Wed 2/18

2:33 pm-8:06 pm

1 stop6h 33m

Kansas City

Sat 2/21

9:10 am-4:44 pm

1 stop6h 34m

$259

HarrisburgKansas City

MDT - MCI

MDTMCI

Harrisburg

Tue 2/17

5:40 pm-9:59 pm

1 stop5h 19m

Kansas City

Sat 2/21

9:10 am-4:44 pm

1 stop6h 34m

$259

HarrisburgSpringfield

MDT - SGF

MDTSGF

Harrisburg

Fri 1/9

10:34 am-8:36 pm

2 stops11h 02m

Springfield-Branson

Sat 1/10

3:14 pm-9:05 pm

1 stop4h 51m

$264

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

Fri 1/23

6:02 pm-11:37 pm

1 stop6h 35m

Lambert-St Louis

Mon 1/26

5:56 pm-10:56 pm

1 stop4h 00m

$269

HarrisburgKansas City

MDT - MCI

MDTMCI

Harrisburg

Wed 1/7

5:35 pm-9:59 pm

1 stop5h 24m

Kansas City

Tue 1/13

3:24 pm-9:05 pm

1 stop4h 41m

$269

HarrisburgKansas City

MDT - MCI

MDTMCI

Harrisburg

Wed 1/7

7:00 am-2:30 pm

2 stops8h 30m

Kansas City

Tue 1/13

6:34 pm-11:50 pm

1 stop4h 16m

$274

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

Tue 2/24

7:20 am-1:54 pm

1 stop7h 34m

Lambert-St Louis

Thu 3/5

6:00 am-11:33 am

1 stop4h 33m

$280

HarrisburgKansas City

MDT - MCI

MDTMCI

Harrisburg

Sun 12/21

3:00 pm-8:31 pm

1 stop6h 31m

Kansas City

Wed 12/24

3:19 pm-12:07 am

1 stop7h 48m

$288

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/11

Showing 1-10 of 39 results
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Best time to book a flight from Harrisburg to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Missouri

What is the cheapest month to book a flight from Harrisburg to Missouri?

Currently, September is the cheapest month in which you can book a flight from Harrisburg to Missouri (average of $109). Flying from Harrisburg to Missouri in December is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDT to MO?

Find hourly flight availability from Harrisburg to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

Unlike in the evening, when flights are generally more expensive, you can save up to 7% on flights from Harrisburg to Missouri by exploring options for tickets at noon.

How much does it cost to fly round-trip from Harrisburg to Missouri?

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated December 12, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Harrisburg to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Food

7.3

Boarding

8.1

Comfort

7.9

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Food

7.3

Boarding

8.1

Comfort

7.9

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,095 reviews
Delta
7.9
Good
8,007 reviews

Food

7.3

Boarding

8.1

Comfort

7.9

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,050 reviews
Delta
7.9
Good
8,007 reviews

Food

7.3

Boarding

8.1

Comfort

7.9

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Harrisburg to Missouri?

    Harrisburg (MDT) is the airport you will fly out of if you book a flight from Harrisburg to Missouri. It is only a 8.5 mi journey to Harrisburg (MDT) from Harrisburg’s city center.

  • How long is the flight from Harrisburg to Missouri?

    Airlines like Delta, American Airlines, and United Airlines fly from Harrisburg to Missouri in about 4h 46m. The time it takes to get you to your destination can typically vary by up to 3h 07m. Airlines will cover a distance of 731 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Harrisburg to Missouri?

    When deciding which route to take from Harrisburg to Missouri consider Harrisburg - Springfield-Branson, Harrisburg - Lambert-St Louis or Harrisburg - Kansas City as they are the most popular.

  • Can I find deals for flights from Harrisburg to Missouri that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Missouri.

  • Can I find deals for business class flights from Harrisburg to Missouri?

    Yes. Cheapflights offers flight deals from Harrisburg to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to Missouri?

    Currently, September is the cheapest month in which you can book a flight from Harrisburg to Missouri (average of $109). Flying from Harrisburg to Missouri in December is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Harrisburg to Missouri

Discover the top 3 airlines that operate flights from Harrisburg to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$219Average$326FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$248Average$413FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$248Average$361FlexibilityNo cancel feeOn-time71%

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