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Missouri

$145+ Cheap flights from Harrisburg (MDT) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/27. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — STL
Apr 14 — Apr 211
Tue 4/14
Tue 4/21
1 adult, Economy
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Cheap flight deals from Harrisburg to Missouri

Cheapest flights from Harrisburg to Missouri
Explore the most affordable flight options available from Harrisburg to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 15, 2026.

This Booking.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/2610:13 pm
MDT
-
STL
1 stop9h 49m
Frontier
Mon 3/304:51 pm
STL
-
MDT
1 stop24h 07m
Frontier
Deal found 3/11$282
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/166:43 pm
MDT
-
STL
1 stop6h 13m
American Airlines
Mon 5/185:21 pm
STL
-
MDT
1 stop5h 31m
American Airlines
Deal found 3/10$289
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:00 am
MDT
-
STL
1 stop4h 42m
Delta
Sat 4/185:59 pm
STL
-
MDT
1 stop4h 04m
Delta
Deal found 3/11$291
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:19 pm
MDT
-
STL
1 stop6h 17m
Delta
Sat 4/185:59 pm
STL
-
MDT
1 stop4h 04m
Delta
Deal found 3/11$300
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/99:11 pm
MDT
-
STL
1 stop27h 47m
Multiple Airlines
Thu 4/169:50 am
STL
-
MDT
2 stops29h 10m
Multiple Airlines
Deal found 3/10$303
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:00 am
MDT
-
MCI
1 stop4h 49m
Delta
Sat 4/2510:36 am
MCI
-
MDT
1 stop4h 02m
Delta
Deal found 3/12$309
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:43 pm
MDT
-
STL
1 stop6h 03m
American Airlines
Thu 4/166:29 am
STL
-
MDT
1 stop6h 49m
American Airlines
Deal found 3/10$309
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/224:36 pm
MDT
-
SGF
1 stop7h 02m
American Airlines
Sat 4/2510:21 am
SGF
-
MDT
1 stop6h 40m
American Airlines
Deal found 3/12$311
This Delta deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/214:19 pm
MDT
-
STL
1 stop5h 25m
Delta
Sat 4/255:59 pm
STL
-
MDT
1 stop4h 04m
Delta
Deal found 3/13$311
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:15 am
MDT
-
MCI
2 stops7h 07m
United Airlines
Tue 7/71:03 pm
MCI
-
MDT
1 stop7h 26m
United Airlines
Deal found 3/11$314
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/266:15 am
MDT
-
MCI
1 stop7h 04m
United Airlines
Thu 3/265:40 pm
MCI
-
MDT
1 stop4h 33m
United Airlines
Deal found 3/10$319
This Delta deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:00 am
MDT
-
STL
1 stop4h 48m
Delta
Mon 6/85:30 pm
STL
-
MDT
1 stop5h 11m
Delta
Deal found 3/13$320

Find flight deals from Harrisburg to Missouri

Keep the following information in mind while searching for Harrisburg to Missouri flight deals. Data was last updated March 15, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$282
(Booking.com)

One-way from

$145
(American Airlines)

Popular in

March

Cheapest in

May

Average price

$466
Provider with most accurate pricing for Harrisburg-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Harrisburg-Lambert-St Louis flights.
Search Deals
From Harrisburg to Missouri
Search Deals
One-way flight from Harrisburg to Missouri
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($33 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 15, 2026.
Use the filters below to find and compare flights from Harrisburg to Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

Wed 4/15

6:00 am-9:42 am

1 stop4h 42m

Lambert-St Louis

Sat 4/18

5:59 pm-11:03 pm

1 stop4h 04m

$291

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

Fri 4/17

6:19 pm-11:36 pm

1 stop6h 17m

Lambert-St Louis

Wed 4/22

5:59 pm-11:03 pm

1 stop4h 04m

$300

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

Tue 3/31

6:00 am-9:29 am

1 stop4h 29m

Lambert-St Louis

Sat 4/4

11:50 am-7:00 pm

1 stop6h 10m

$309

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

Thu 7/30

6:30 am-12:11 pm

1 stop6h 41m

Lambert-St Louis

Sun 8/2

1:13 pm-9:01 pm

1 stop6h 48m

$309

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

Thu 4/16

5:52 pm-9:13 pm

1 stop4h 21m

Lambert-St Louis

Sun 4/19

9:10 am-4:51 pm

1 stop6h 41m

$309

HarrisburgKansas City

MDT - MCI

MDTMCI

Harrisburg

Sat 4/11

6:15 am-12:24 pm

2 stops7h 09m

Kansas City

Mon 4/13

1:05 pm-9:18 pm

1 stop7h 13m

$342

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

Thu 4/2

5:52 pm-9:13 pm

1 stop4h 21m

Lambert-St Louis

Sun 4/5

7:45 am-1:30 pm

1 stop4h 45m

$350

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

Fri 4/24

5:53 pm-9:52 pm

1 stop4h 59m

Lambert-St Louis

Tue 4/28

7:45 am-1:33 pm

1 stop4h 48m

$370

HarrisburgKansas City

MDT - MCI

MDTMCI

Harrisburg

Sat 4/11

6:15 am-10:27 am

1 stop5h 12m

Kansas City

Tue 4/14

9:55 am-4:51 pm

1 stop5h 56m

$374

HarrisburgSpringfield

MDT - SGF

MDTSGF

Harrisburg

Sat 8/22

5:53 pm-9:58 pm

1 stop5h 05m

Springfield-Branson

Wed 8/26

11:18 am-4:51 pm

1 stop4h 33m

$381

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/10

Showing 1-10 of 48 resultsSorted by cheapest first
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5

Best time to book a flight from Harrisburg to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Missouri

What is the cheapest month to book a flight from Harrisburg to Missouri?

Currently, September is the cheapest month in which you can book a flight from Harrisburg to Missouri (average of $109). Flying from Harrisburg to Missouri in December is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Harrisburg to Missouri?

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated March 15, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from Harrisburg to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,293 reviews

Food

7.2

Entertainment

7.8

Comfort

7.9

Crew

8.5

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,293 reviews
Delta
7.9
Good
8,293 reviews

Food

7.2

Entertainment

7.8

Comfort

7.9

Crew

8.5

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,427 reviews
Delta
7.9
Good
8,293 reviews

Food

7.2

Entertainment

7.8

Comfort

7.9

Crew

8.5

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,472 reviews
Delta
7.9
Good
8,293 reviews

Food

7.2

Entertainment

7.8

Comfort

7.9

Crew

8.5

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Harrisburg to Missouri?

    Harrisburg (MDT) is the airport you will fly out of if you book a flight from Harrisburg to Missouri. It is only a 8.5 mi journey to Harrisburg (MDT) from Harrisburg’s city center.

  • How long is the flight from Harrisburg to Missouri?

    Airlines like American Airlines, Delta, and United Airlines fly from Harrisburg to Missouri in about 4h 29m. The time it takes to get you to your destination can typically vary by up to 2h 12m. Airlines will cover a distance of 731 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Harrisburg to Missouri one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $99. United Airlines flights start at $99 while deals on Delta start at $124 one-way.

  • What are the most popular routes from Harrisburg to Missouri?

    When deciding which route to take from Harrisburg to Missouri consider Harrisburg - Springfield-Branson, Harrisburg - Lambert-St Louis or Harrisburg - Kansas City as they are the most popular.

  • Can I find deals for flights from Harrisburg to Missouri that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Missouri.

  • Can I find deals for business class flights from Harrisburg to Missouri?

    Yes. Cheapflights offers flight deals from Harrisburg to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to Missouri?

    Currently, September is the cheapest month in which you can book a flight from Harrisburg to Missouri (average of $109). Flying from Harrisburg to Missouri in December is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Harrisburg to Missouri

Discover the top 3 airlines that operate flights from Harrisburg to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 15, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$219Average$323FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$248Average$418FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$248Average$359FlexibilityNo cancel feeOn-time71%

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