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$100+ Cheap flights from Harrisburg (MDT) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/7. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — STL
nov. 27 — déc. 41
jeu. 11/27
jeu. 12/4
1 adult, Economy
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Cheap flight deals from Harrisburg to Missouri

Keep the following information in mind while searching for Harrisburg to Missouri flight deals. Data was last updated octobre 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$203
(Frontier)

One-way from

$100
(Booking.com)

Popular in

December

Cheapest in

April

Average price

$308
Provider with most accurate pricing for Harrisburg-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Harrisburg-Lambert-St Louis flights.
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From Harrisburg to Missouri
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One-way flight from Harrisburg to Missouri
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Highest demand for flights based on searches. 2% potential increase in price ($9 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Harrisburg to Missouri

Cheapest flights from Harrisburg to Missouri
Explore the most affordable flight options available from Harrisburg to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octobre 28, 2025.

This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 11/56:25 pmMDT - MCI
1 stop6h 14mDelta
sam. 11/85:51 pmMCI - MDT
1 stop4h 09mDelta
Deal found 10/28$249
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 11/126:00 amMDT - STL
1 stop5h 43mDelta
lun. 11/175:17 pmSTL - MDT
1 stop4h 54mDelta
Deal found 10/27$249
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 11/55:40 amMDT - MCI
1 stop7h 15mAmerican Airlines
sam. 11/81:45 pmMCI - MDT
2 stops7h 30mAmerican Airlines
Deal found 10/28$254
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/116:53 amMDT - STL
2 stops7h 20mAmerican Airlines
sam. 11/158:39 amSTL - MDT
1 stop5h 29mAmerican Airlines
Deal found 10/27$254
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 12/174:25 pmMDT - MCI
1 stop8h 20mAmerican Airlines
sam. 12/206:36 pmMCI - MDT
1 stop4h 43mAmerican Airlines
Deal found 10/27$269
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/257:33 pmMDT - STL
1 stop5h 32mAmerican Airlines
mar. 12/25:56 pmSTL - MDT
1 stop4h 57mAmerican Airlines
Deal found 10/26$274
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 11/206:00 amMDT - MCI
1 stop6h 13mDelta
lun. 11/245:12 pmMCI - MDT
1 stop4h 59mDelta
Deal found 10/27$294
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 12/47:27 pmMDT - STL
1 stop5h 15mDelta
dim. 12/76:05 pmSTL - MDT
1 stop4h 02mDelta
Deal found 10/26$294
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 12/189:30 amMDT - STL
2 stops10h 06mMultiple Airlines
lun. 12/224:27 pmSTL - MDT
1 stop16h 34mMultiple Airlines
Deal found 10/27$300
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 11/146:30 amMDT - MCI
2 stops10h 35mUnited Airlines
dim. 11/166:00 amMCI - MDT
2 stops6h 58mUnited Airlines
Deal found 10/26$307
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 10/316:10 amMDT - STL
1 stop4h 27mDelta
dim. 11/25:40 amSTL - MDT
1 stop4h 13mDelta
Deal found 10/27$310
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 11/206:30 amMDT - MCI
1 stop5h 10mUnited Airlines
lun. 11/246:00 amMCI - MDT
2 stops9h 53mUnited Airlines
Deal found 10/27$314

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octobre 28, 2025.
Use the filters below to find and compare flights from Harrisburg to Missouri that are best for you.

Fly from

Harrisburg

Fly to

Missouri

Route

Depart

Return

Price

HarrisburgKansas City

MDT - MCI

MDTMCI

Harrisburg

ven. 11/14

6:20 am-12:49 pm

1 stop7h 29m

Kansas City

dim. 11/16

2:54 pm-10:56 pm

1 stop7h 02m

$249

HarrisburgKansas City

MDT - MCI

MDTMCI

Harrisburg

mer. 11/26

7:12 pm-11:50 pm

1 stop5h 38m

Kansas City

mer. 12/3

6:29 am-11:56 am

1 stop4h 27m

$249

HarrisburgKansas City

MDT - MCI

MDTMCI

Harrisburg

jeu. 2/19

6:29 am-10:36 am

1 stop5h 07m

Kansas City

mar. 2/24

3:27 pm-9:06 pm

1 stop4h 39m

$249

HarrisburgKansas City

MDT - MCI

MDTMCI

Harrisburg

sam. 12/6

6:00 am-10:09 am

1 stop5h 09m

Kansas City

mar. 12/16

3:27 pm-11:13 pm

1 stop6h 46m

$249

HarrisburgKansas City

MDT - MCI

MDTMCI

Harrisburg

jeu. 11/20

7:12 pm-11:50 pm

1 stop5h 38m

Kansas City

dim. 11/23

5:47 pm-11:04 pm

1 stop4h 17m

$249

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

mar. 11/11

6:00 am-9:46 am

1 stop4h 46m

Lambert-St Louis

sam. 11/15

6:00 am-12:16 pm

1 stop5h 16m

$249

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

mer. 11/12

6:00 am-10:43 am

1 stop5h 43m

Lambert-St Louis

lun. 11/17

6:09 pm-11:04 pm

1 stop3h 55m

$249

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

sam. 11/22

6:00 am-10:23 am

1 stop5h 23m

Lambert-St Louis

dim. 11/23

5:17 pm-11:11 pm

1 stop4h 54m

$249

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

jeu. 11/6

6:00 am-10:26 am

1 stop5h 26m

Lambert-St Louis

sam. 11/8

6:40 am-11:40 am

1 stop4h 00m

$249

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

ven. 12/5

6:00 am-9:50 am

1 stop4h 50m

Lambert-St Louis

sam. 12/6

5:12 pm-11:13 pm

1 stop5h 01m

$249

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Showing 1-10 of 44 results
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Best time to book a flight from Harrisburg to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Missouri

What is the cheapest month to book a flight from Harrisburg to Missouri?

Currently, September is the cheapest month in which you can book a flight from Harrisburg to Missouri (average of $109). Flying from Harrisburg to Missouri in December is currently the most expensive (average of $235). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDT to MO?

Find hourly flight availability from Harrisburg to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated octobre 28, 2025.

Unlike in the evening, when flights are generally more expensive, you can save up to 7% on flights from Harrisburg to Missouri by exploring options for tickets at noon.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated octobre 28, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Harrisburg to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,994 reviews

Boarding

8.2

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,994 reviews
Delta
7.9
Good
7,994 reviews

Boarding

8.2

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
9,001 reviews
Delta
7.9
Good
7,994 reviews

Boarding

8.2

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,032 reviews
Delta
7.9
Good
7,994 reviews

Boarding

8.2

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Harrisburg to Missouri?

    Harrisburg (MDT) is the airport you will fly out of if you book a flight from Harrisburg to Missouri. It is only a 8.5 mi journey to Harrisburg (MDT) from Harrisburg’s city center.

  • How long is the flight from Harrisburg to Missouri?

    Airlines like American Airlines, Delta, and United Airlines fly from Harrisburg to Missouri in about 5h 07m. The time it takes to get you to your destination can typically vary by up to 2h 22m. Airlines will cover a distance of 954 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Harrisburg to Missouri one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $125. United Airlines flights start at $125 while deals on American Airlines start at $130 one-way.

  • What are the most popular routes from Harrisburg to Missouri?

    When deciding which route to take from Harrisburg to Missouri consider Harrisburg - Springfield-Branson, Harrisburg - Kansas City or Harrisburg - Lambert-St Louis as they are the most popular.

  • Can I find deals for flights from Harrisburg to Missouri that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Missouri.

  • Can I find deals for business class flights from Harrisburg to Missouri?

    Yes. Cheapflights offers flight deals from Harrisburg to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to Missouri?

    Currently, September is the cheapest month in which you can book a flight from Harrisburg to Missouri (average of $109). Flying from Harrisburg to Missouri in December is currently the most expensive (average of $235). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Harrisburg to Missouri

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Top 3 airlines flying from Harrisburg to Missouri

Discover the top 3 airlines that operate flights from Harrisburg to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octobre 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$219Average$327FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$248Average$418FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$248Average$377FlexibilityNo cancel feeOn-time71%

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