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Missouri

$147+ Cheap flights from Greenville (GSP) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/9. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — STL
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Greenville to Missouri

Cheapest flights from Greenville to Missouri
Explore the most affordable flight options available from Greenville to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/259:45 amGSP - STL
1 stop4h 29mAmerican Airlines
Mon 12/296:00 pmSTL - GSP
1 stop5h 51mAmerican Airlines
Deal found 12/10$351
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:00 amGSP - SGF
1 stop5h 05mAmerican Airlines
Sun 12/145:58 pmSGF - GSP
1 stop4h 53mAmerican Airlines
Deal found 12/10$409
This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2511:33 amGSP - STL
1 stop12h 00mMultiple Airlines
Mon 12/294:27 pmSTL - GSP
2 stops46h 28mMultiple Airlines
Deal found 12/10$425
This Southwest deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/254:45 pmGSP - STL
1 stop6h 15mSouthwest
Sun 12/2810:30 amSTL - GSP
2 stops10h 25mSouthwest
Deal found 12/10$441
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2512:01 pmGSP - STL
1 stop8h 21mAmerican Airlines
Sun 12/285:00 amSTL - GSP
1 stop6h 19mAmerican Airlines
Deal found 12/10$452
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/115:00 pmGSP - SGF
1 stop5h 59mUnited Airlines
Sun 12/146:15 amSGF - GSP
2 stops13h 34mUnited Airlines
Deal found 12/10$515
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:45 amGSP - MCI
1 stop8h 28mUnited Airlines
Tue 12/308:09 amMCI - GSP
1 stop7h 54mUnited Airlines
Deal found 12/11$537
This American Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1610:26 amGSP - STL
1 stop6h 40mAmerican Airlines
Tue 12/165:30 pmSTL - GSP
1 stop5h 48mAmerican Airlines
Deal found 12/9$571
This United Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/166:00 amGSP - STL
1 stop5h 50mUnited Airlines
Tue 12/1612:55 pmSTL - GSP
2 stops10h 04mUnited Airlines
Deal found 12/9$576
This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2012:43 pmGSP - STL
1 stop4h 45mDelta
Sun 12/217:02 pmSTL - GSP
1 stop3h 30mDelta
Deal found 12/10$577
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/209:40 amGSP - STL
2 stops9h 14mUnited Airlines
Sun 12/219:55 amSTL - GSP
1 stop6h 06mUnited Airlines
Deal found 12/11$582
This Delta deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1612:00 pmGSP - STL
1 stop5h 06mDelta
Fri 12/192:38 pmSTL - GSP
1 stop6h 04mDelta
Deal found 12/11$709

Find flight deals from Greenville to Missouri

Keep the following information in mind while searching for Greenville to Missouri flight deals. Data was last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$269
(Southwest)

One-way from

$147
(Kiwi.com)

Popular in

December

Cheapest in

October

Average price

$576
Provider with most accurate pricing for Greenville-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Greenville-Lambert-St Louis flights.
Search Deals
From Greenville to Missouri
Search Deals
One-way flight from Greenville to Missouri
Search Deals
Highest demand for flights based on searches. 19% potential increase in price ($98 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Greenville to Missouri that are best for you.

Fly from

Greenville

Fly to

Missouri

Route

Depart

Return

Price

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Tue 1/13

6:50 am-11:05 am

1 stop5h 15m

Lambert-St Louis

Wed 1/14

7:10 am-2:15 pm

1 stop6h 05m

$297

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Tue 1/13

11:15 am-7:05 pm

2 stops8h 50m

Lambert-St Louis

Wed 1/14

11:35 am-5:35 pm

1 stop5h 00m

$302

GreenvilleKansas City

GSP - MCI

GSPMCI

Greenville

Wed 1/7

5:12 pm-10:51 pm

1 stop6h 39m

Kansas City

Fri 1/9

4:00 pm-9:52 pm

1 stop4h 52m

$337

GreenvilleSpringfield

GSP - SGF

GSPSGF

Greenville

Wed 1/7

5:34 pm-9:58 pm

1 stop5h 24m

Springfield-Branson

Sat 1/10

3:14 pm-8:47 pm

1 stop4h 33m

$339

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Thu 12/25

9:45 am-1:14 pm

1 stop4h 29m

Lambert-St Louis

Mon 12/29

6:00 pm-12:51 am

1 stop5h 51m

$351

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Sun 1/18

10:51 am-2:30 pm

1 stop4h 39m

Lambert-St Louis

Thu 1/22

11:20 am-4:52 pm

1 stop4h 32m

$360

GreenvilleKansas City

GSP - MCI

GSPMCI

Greenville

Fri 1/9

10:05 am-5:30 pm

1 stop8h 25m

Kansas City

Sun 1/11

7:15 am-11:55 am

1 stop3h 40m

$387

GreenvilleKansas City

GSP - MCI

GSPMCI

Greenville

Mon 1/26

6:35 am-10:32 am

1 stop4h 57m

Kansas City

Thu 1/29

10:00 am-4:52 pm

1 stop5h 52m

$391

GreenvilleKansas City

GSP - MCI

GSPMCI

Greenville

Fri 1/2

5:45 am-9:52 am

1 stop5h 07m

Kansas City

Sun 1/11

5:50 am-11:08 am

1 stop4h 18m

$397

GreenvilleSpringfield

GSP - SGF

GSPSGF

Greenville

Sun 6/7

6:45 am-11:07 am

1 stop5h 22m

Springfield-Branson

Sun 6/14

6:00 am-1:10 pm

1 stop6h 10m

$399

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 30 results
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Best time to book a flight from Greenville to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Missouri

What is the cheapest month to book a flight from Greenville to Missouri?

Currently, June is the cheapest month in which you can book a flight from Greenville to Missouri (average of $108). Flying from Greenville to Missouri in August is currently the most expensive (average of $217). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GSP to MO?

Find hourly flight availability from Greenville to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

It’s optimal to fly from Greenville to Missouri at noon. By choosing this option you can save up to 10% on the cost of your flight, compared to a flight in the morning.

What is the cheapest day to fly from Greenville to Missouri?

Use this chart to determine the cheapest time to fly round-trip from Greenville to Missouri. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Greenville to Missouri flight should consider departing on Tuesday evenings when fares are most often at their lowest. Wednesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated December 12, 2025.
Read reviews from past customers who have flown Southwest, Delta, and American Airlines from Greenville to Missouri. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
7.9
Good
4,253 reviews

Food

7.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
7.9
Good
4,253 reviews
Southwest
7.9
Good
4,253 reviews

Food

7.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,008 reviews
Southwest
7.9
Good
4,253 reviews

Food

7.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,050 reviews
Southwest
7.9
Good
4,253 reviews

Food

7.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Greenville to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Greenville to Missouri?

    Located just 10.4 mi from the city center, Greenville (GSP) is the airport most travelers will use when flying to Missouri from Greenville.

  • How long is the flight from Greenville to Missouri?

    Airlines like Southwest, Delta, and United Airlines fly from Greenville to Missouri in about 5h 15m. The time it takes to get you to your destination can typically vary by up to 25m. Airlines will cover a distance of 523 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Greenville to Missouri?

    The most popular route from Greenville to Missouri is Greenville - Kansas City. You may also consider Greenville - Lambert-St Louis or Greenville - Springfield-Branson.

  • Can I find deals for flights from Greenville to Missouri that include hotel bookings?

    Yes. In addition to deals on Greenville to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Missouri.

  • Can I find deals for business class flights from Greenville to Missouri?

    Yes. Cheapflights offers flight deals from Greenville to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Missouri?

    Currently, June is the cheapest month in which you can book a flight from Greenville to Missouri (average of $108). Flying from Greenville to Missouri in August is currently the most expensive (average of $217). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Greenville to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Greenville to Missouri

Discover the top 3 airlines that operate flights from Greenville to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$232Average$335FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$236Average$459FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$248Average$383FlexibilityNo cancel feeOn-time71%

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