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$85+ Cheap flights from St. Louis (STL) to Mississippi

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/5. Fares are subject to change and may not be available on all flights or dates of travel.
STL — JAN
Nov 20 — Nov 271
Thu 11/20
Thu 11/27
1 adult, Economy
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Find flight deals from St. Louis to Mississippi

Cheapest flights from St. Louis to Mississippi
Explore the most affordable flight options available from St. Louis to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 21, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/57:45 pmSTL - MEM
1 stop23h 37mMultiple Airlines
Sun 11/98:22 amMEM - STL
1 stop8h 54mMultiple Airlines
Deal found 10/21$233
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1010:25 amSTL - MEM
1 stop9h 35mMultiple Airlines
Mon 11/178:10 pmMEM - STL
1 stop12h 57mMultiple Airlines
Deal found 10/19$234
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/188:20 amSTL - GPT
1 stop7h 42mUnited Airlines
Tue 11/2511:52 amGPT - STL
1 stop6h 55mUnited Airlines
Deal found 10/19$249
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/35:10 amSTL - MOB
1 stop4h 44mAmerican Airlines
Wed 12/102:55 pmMOB - STL
1 stop4h 34mAmerican Airlines
Deal found 10/19$249
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/149:30 amSTL - BTR
1 stop4h 06mDelta
Wed 1/285:00 pmBTR - STL
1 stop6h 40mDelta
Deal found 10/20$249
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/57:45 pmSTL - MEM
1 stop23h 37mFrontier
Sun 11/98:00 pmMEM - STL
1 stop13h 07mFrontier
Deal found 10/19$250
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:35 pmSTL - MEM
1 stop5h 21mAmerican Airlines
Tue 12/3012:00 pmMEM - STL
1 stop7h 31mAmerican Airlines
Deal found 10/21$252
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1411:34 amSTL - BTR
1 stop6h 06mAmerican Airlines
Wed 1/286:00 amBTR - STL
2 stops8h 50mAmerican Airlines
Deal found 10/20$254
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/68:38 amSTL - MEM
1 stop10h 19mAmerican Airlines
Mon 12/87:00 amMEM - STL
1 stop12h 29mAmerican Airlines
Deal found 10/20$256
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/45:15 pmSTL - GPT
1 stop4h 35mDelta
Sat 11/86:00 amGPT - STL
1 stop6h 35mDelta
Deal found 10/20$259
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/47:05 amSTL - MOB
1 stop5h 27mDelta
Sat 11/89:13 amMOB - STL
1 stop5h 30mDelta
Deal found 10/20$259
This Kiwi.com deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/87:45 pmSTL - MEM
2 stops15h 43mMultiple Airlines
Mon 11/108:10 pmMEM - STL
1 stop12h 57mMultiple Airlines
Deal found 10/18$260

Cheap flight deals from St. Louis to Mississippi

Keep the following information in mind while searching for St. Louis to Mississippi flight deals. Data was last updated October 21, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$233
(Kiwi.com)

One-way from

$85
(Trip.com)

Popular in

February

Cheapest in

August

Average price

$315
Provider with most accurate pricing for Lambert-St Louis-Jackson-Evers Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Jackson-Evers Intl flights.
Search Deals
From Lambert-St Louis to Mississippi
Search Deals
One-way flight from Lambert-St Louis to Mississippi
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($58 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($27 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 21, 2025.
Use the filters below to find and compare flights from St. Louis to Mississippi that are best for you.

Fly from

St. Louis

Fly to

Mississippi

Route

Depart

Return

Price

St. LouisMemphis

STL - MEM

STLMEM

Lambert-St Louis

Wed 11/5

7:45 pm-7:22 pm

1 stop23h 37m

Memphis

Sun 11/9

8:22 am-5:16 pm

1 stop8h 54m

$233

St. LouisMemphis

STL - MEM

STLMEM

Lambert-St Louis

Mon 11/10

10:25 am-8:00 pm

1 stop9h 35m

Memphis

Mon 11/17

8:10 pm-9:07 am

1 stop12h 57m

$234

St. LouisGulfport

STL - GPT

STLGPT

Lambert-St Louis

Fri 12/5

6:00 am-9:50 am

1 stop3h 50m

Gulfport Biloxi Regional

Mon 12/8

6:01 pm-11:42 pm

1 stop5h 41m

$249

St. LouisGulfport

STL - GPT

STLGPT

Lambert-St Louis

Tue 11/18

8:20 am-4:02 pm

1 stop7h 42m

Gulfport Biloxi Regional

Tue 11/25

11:52 am-6:47 pm

1 stop6h 55m

$249

St. LouisMobile

STL - MOB

STLMOB

Lambert-St Louis

Wed 12/3

5:10 am-9:54 am

1 stop4h 44m

Mobile

Wed 12/10

2:55 pm-7:29 pm

1 stop4h 34m

$249

St. LouisBaton Rouge

STL - BTR

STLBTR

Lambert-St Louis

Sun 12/14

9:30 am-1:36 pm

1 stop4h 06m

Baton Rouge Ryan

Wed 1/28

5:00 pm-11:40 pm

1 stop6h 40m

$249

St. LouisBaton Rouge

STL - BTR

STLBTR

Lambert-St Louis

Wed 2/18

10:00 am-3:56 pm

1 stop5h 56m

Baton Rouge Ryan

Sat 2/21

10:31 am-4:01 pm

1 stop5h 30m

$249

St. LouisMemphis

STL - MEM

STLMEM

Lambert-St Louis

Wed 11/5

7:45 pm-7:22 pm

1 stop23h 37m

Memphis

Sun 11/9

8:00 pm-9:07 am

1 stop13h 07m

$250

St. LouisBaton Rouge

STL - BTR

STLBTR

Lambert-St Louis

Sun 12/14

11:34 am-5:40 pm

1 stop6h 06m

Baton Rouge Ryan

Wed 1/28

6:00 am-2:50 pm

2 stops8h 50m

$254

St. LouisMemphis

STL - MEM

STLMEM

Lambert-St Louis

Sat 12/6

8:38 am-6:57 pm

1 stop10h 19m

Memphis

Mon 12/8

7:00 am-7:29 pm

1 stop12h 29m

$256

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/20

Showing 1-10 of 50 results
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Best time to book a flight from St. Louis to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Mississippi

What is the cheapest month to book a flight from St. Louis to Mississippi?

Currently, October is the cheapest month in which you can book a flight from St. Louis to Mississippi (average of $120). Flying from St. Louis to Mississippi in June is currently the most expensive (average of $323). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to MS?

Find hourly flight availability from St. Louis to Mississippi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 21, 2025.

A simple way to save on the total cost of your ticket is to fly from St. Louis to Mississippi in the morning. If you’re flexible enough to do this you can expect to save up to 28% on your trip compared to booking a flight in the afternoon.

How much does it cost to fly round-trip from St. Louis to Mississippi?

Reviews of airlines servicing Mississippi

Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated October 21, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from St. Louis to Mississippi by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,978 reviews

Comfort

7.9

Food

7.3

Crew

8.5

Boarding

8.2

Overall

7.9

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,978 reviews
Delta
7.9
Good
7,978 reviews

Comfort

7.9

Food

7.3

Crew

8.5

Boarding

8.2

Overall

7.9

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,991 reviews
Delta
7.9
Good
7,978 reviews

Comfort

7.9

Food

7.3

Crew

8.5

Boarding

8.2

Overall

7.9

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,023 reviews
Delta
7.9
Good
7,978 reviews

Comfort

7.9

Food

7.3

Crew

8.5

Boarding

8.2

Overall

7.9

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Mississippi?

    If you book a flight to Mississippi from St. Louis, you will be flying from Lambert-St Louis, which is the city’s only airport. Lambert-St Louis (STL) is located 12.7 mi from the center of St. Louis.

  • How long is the flight from St. Louis to Mississippi?

    Departing from St. Louis to Mississippi will take you 3h 50m. The distance from St. Louis to Mississippi is about 581 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from St. Louis to Mississippi one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $85. Users have also found prices from $122 and $127 on American Airlines and Southwest, respectively.

  • What are the most popular routes from St. Louis to Mississippi?

    The most popular route from St. Louis to Mississippi is Lambert-St Louis - Gulfport Biloxi Regional. You may also consider Lambert-St Louis - Baton Rouge Ryan or Lambert-St Louis - Mobile.

  • Can I find deals for flights from St. Louis to Mississippi that include hotel bookings?

    Yes. In addition to deals on St. Louis to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Mississippi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Mississippi.

  • Can I find deals for business class flights from St. Louis to Mississippi?

    Yes. Cheapflights offers flight deals from St. Louis to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Mississippi?

    Currently, October is the cheapest month in which you can book a flight from St. Louis to Mississippi (average of $120). Flying from St. Louis to Mississippi in June is currently the most expensive (average of $323). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for St. Louis to Mississippi

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from St. Louis to Mississippi

Discover the top 3 airlines that operate flights from St. Louis to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$207Average$407FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$312FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$248Average$323FlexibilityNo cancel feeOn-time69%

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