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$147+ Cheap flights from St. Louis (STL) to Mississippi

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
STL — JAN
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from St. Louis to Mississippi

Keep the following information in mind while searching for St. Louis to Mississippi flight deals. Data was last updated September 16, 2025.

Round-trip from

$195
(American Airlines)

One-way from

$147
(American Airlines)

Popular in

February

Cheapest in

August

Average price

$237
From Lambert-St Louis to Mississippi
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One-way flight from Lambert-St Louis to Mississippi
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Highest demand for flights based on searches. 14% potential increase in price ($60 potential increase over avg. RT price).
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Cheapest flight prices on average. 8% potential price decrease ($28 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from St. Louis to Mississippi

Cheapest flights from St. Louis to Mississippi
Explore the most affordable flight options available from St. Louis to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/175:17 amSTL - BTR
1 stop4h 36mAmerican Airlines
Tue 11/185:27 pmBTR - STL
1 stop5h 40mAmerican Airlines
Deal found 9/15$195
This Booking.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/17:55 pmSTL - MEM
1 stop21h 53mFrontier
Sun 10/58:04 pmMEM - STL
1 stop13h 02mFrontier
Deal found 9/16$202
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/156:15 amSTL - JAN
1 stop4h 59mUnited Airlines
Wed 10/222:05 pmJAN - STL
1 stop4h 52mUnited Airlines
Deal found 9/15$237
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/146:15 amSTL - GPT
1 stop7h 10mUnited Airlines
Tue 10/215:25 pmGPT - STL
1 stop4h 35mUnited Airlines
Deal found 9/15$249
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/183:59 pmSTL - MOB
1 stop6h 49mDelta
Mon 10/206:59 pmMOB - STL
1 stop4h 42mDelta
Deal found 9/15$249
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/145:15 pmSTL - BTR
1 stop4h 32mDelta
Tue 10/216:15 amBTR - STL
1 stop6h 20mDelta
Deal found 9/15$249
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/141:28 pmSTL - GPT
2 stops9h 18mAmerican Airlines
Tue 10/216:26 pmGPT - STL
1 stop4h 52mAmerican Airlines
Deal found 9/15$254
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/306:15 amSTL - GPT
1 stop7h 10mUnited Airlines
Sat 10/45:25 pmGPT - STL
1 stop4h 33mUnited Airlines
Deal found 9/15$259
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/301:26 pmSTL - MOB
1 stop4h 46mDelta
Sat 10/46:00 amMOB - STL
1 stop6h 21mDelta
Deal found 9/15$259
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/249:59 pmSTL - MEM
1 stop16h 03mMultiple Airlines
Mon 10/271:45 pmMEM - STL
2 stops19h 22mMultiple Airlines
Deal found 9/14$260
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/156:15 amSTL - MOB
1 stop5h 28mUnited Airlines
Wed 10/2211:30 amMOB - STL
1 stop7h 27mUnited Airlines
Deal found 9/15$261
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/3011:10 amSTL - MOB
2 stops10h 38mUnited Airlines
Sat 10/411:30 amMOB - STL
1 stop4h 58mUnited Airlines
Deal found 9/15$264

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from St. Louis to Mississippi that are best for you.

Fly from

St. Louis

Fly to

Mississippi

Route

Depart

Return

Price

St. LouisBaton Rouge

STL - BTR

STLBTR

Lambert-St Louis

Mon 11/17

5:17 am-9:53 am

1 stop4h 36m

Baton Rouge Ryan

Tue 11/18

5:27 pm-11:07 pm

1 stop5h 40m

$195

St. LouisMemphis

STL - MEM

STLMEM

Lambert-St Louis

Wed 10/1

7:55 pm-5:48 pm

1 stop21h 53m

Memphis

Sun 10/5

8:04 pm-9:06 am

1 stop13h 02m

$202

St. LouisJackson

STL - JAN

STLJAN

Lambert-St Louis

Wed 10/15

6:15 am-11:14 am

1 stop4h 59m

Jackson-Evers Intl

Wed 10/22

2:05 pm-6:57 pm

1 stop4h 52m

$237

St. LouisGulfport

STL - GPT

STLGPT

Lambert-St Louis

Wed 2/18

10:00 am-1:37 pm

1 stop3h 37m

Gulfport Biloxi Regional

Sat 2/21

3:00 pm-7:14 pm

1 stop4h 14m

$249

St. LouisGulfport

STL - GPT

STLGPT

Lambert-St Louis

Tue 10/14

6:15 am-1:25 pm

1 stop7h 10m

Gulfport Biloxi Regional

Tue 10/21

5:25 pm-10:00 pm

1 stop4h 35m

$249

St. LouisMobile

STL - MOB

STLMOB

Lambert-St Louis

Sat 11/1

7:05 am-12:32 pm

1 stop5h 27m

Mobile

Sun 11/9

7:12 pm-11:40 pm

1 stop4h 28m

$249

St. LouisMobile

STL - MOB

STLMOB

Lambert-St Louis

Sat 10/18

3:59 pm-10:48 pm

1 stop6h 49m

Mobile

Mon 10/20

6:59 pm-11:41 pm

1 stop4h 42m

$249

St. LouisBaton Rouge

STL - BTR

STLBTR

Lambert-St Louis

Tue 10/14

9:10 am-2:55 pm

1 stop5h 45m

Baton Rouge Ryan

Tue 10/21

6:15 am-10:26 am

1 stop4h 11m

$249

St. LouisBaton Rouge

STL - BTR

STLBTR

Lambert-St Louis

Wed 11/5

1:30 pm-7:31 pm

1 stop6h 01m

Baton Rouge Ryan

Sun 11/9

6:50 pm-11:40 pm

1 stop4h 50m

$249

St. LouisGulfport

STL - GPT

STLGPT

Lambert-St Louis

Tue 9/30

6:15 am-1:25 pm

1 stop7h 10m

Gulfport Biloxi Regional

Sat 10/4

5:25 pm-9:58 pm

1 stop4h 33m

$259

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 50 results
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Best time to book a flight from St. Louis to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Mississippi

What is the cheapest month to book a flight from St. Louis to Mississippi?

Currently, January is the cheapest month in which you can book a flight from St. Louis to Mississippi (average of $371). Flying from St. Louis to Mississippi in March is currently the most expensive (average of $447). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to MS?

Find hourly flight availability from St. Louis to Mississippi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

When flying from St. Louis to Mississippi, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Mississippi

Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated September 16, 2025.
Get a feel of what it's like to fly with Delta and American Airlines from St. Louis to Mississippi by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,957 reviews

Comfort

7.9

Food

7.3

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,957 reviews
Delta
8.0
Very good
7,957 reviews

Comfort

7.9

Food

7.3

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,957 reviews

Comfort

7.9

Food

7.3

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Mississippi?

    If you book a flight to Mississippi from St. Louis, you will be flying from Lambert-St Louis, which is the city’s only airport. Lambert-St Louis (STL) is located 12.7 mi from the center of St. Louis.

  • How long is the flight from St. Louis to Mississippi?

    Departing from St. Louis to Mississippi will take you 4h 36m. The distance from St. Louis to Mississippi is about 569 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from St. Louis to Mississippi one-way?

    For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $147. Users have also found prices from $149 and $159 on United Airlines and Delta, respectively.

  • What are the most popular routes from St. Louis to Mississippi?

    The most popular route from St. Louis to Mississippi is Lambert-St Louis - Baton Rouge Ryan. You may also consider Lambert-St Louis - Mobile or Lambert-St Louis - Gulfport Biloxi Regional.

  • Can I find deals for flights from St. Louis to Mississippi that include hotel bookings?

    Yes. In addition to deals on St. Louis to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Mississippi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Mississippi.

  • Can I find deals for business class flights from St. Louis to Mississippi?

    Yes. Cheapflights offers flight deals from St. Louis to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Mississippi?

    Currently, January is the cheapest month in which you can book a flight from St. Louis to Mississippi (average of $371). Flying from St. Louis to Mississippi in March is currently the most expensive (average of $447). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for St. Louis to Mississippi

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from St. Louis to Mississippi

Discover the top 2 airlines that operate flights from St. Louis to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$207Average$407FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$231Average$317FlexibilityNo cancel feeOn-time71%

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