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$174+ Cheap flights from Myrtle Beach (MYR) to Mississippi

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/12. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — JAN
Nov 27 — Dec 41
Thu 11/27
Thu 12/4
1 adult, Economy
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Find flight deals from Myrtle Beach to Mississippi

Cheapest flights from Myrtle Beach to Mississippi
Explore the most affordable flight options available from Myrtle Beach to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 28, 2025.

This Mytrip deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/122:15 pmMYR - MEM
1 stop5h 32mSpirit Airlines
Mon 12/157:42 pmMEM - MYR
2 stops21h 06mSpirit Airlines
Deal found 10/27$268
This Mytrip deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/276:15 amMYR - MEM
1 stop4h 48mMultiple Airlines
Mon 12/18:50 amMEM - MYR
1 stop14h 04mMultiple Airlines
Deal found 10/26$293
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:56 pmMYR - MEM
1 stop5h 27mDelta
Thu 12/188:05 amMEM - MYR
1 stop4h 49mDelta
Deal found 10/27$297
This Mytrip deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/122:15 pmMYR - MEM
1 stop5h 32mMultiple Airlines
Mon 12/151:45 pmMEM - MYR
3 stops27h 03mMultiple Airlines
Deal found 10/27$316
This Mytrip deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1311:13 amMYR - MEM
2 stops26h 18mMultiple Airlines
Mon 11/178:55 pmMEM - MYR
2 stops15h 56mMultiple Airlines
Deal found 10/26$322
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/125:50 pmMYR - MEM
1 stop6h 35mSouthwest
Mon 12/157:30 amMEM - MYR
1 stop8h 55mSouthwest
Deal found 10/27$327
This Mytrip deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/276:15 amMYR - MEM
1 stop4h 48mSpirit Airlines
Mon 12/19:16 pmMEM - MYR
3 stops25h 38mSpirit Airlines
Deal found 10/26$331
This Mytrip deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:15 amMYR - MEM
3 stops30h 13mSpirit Airlines
Mon 11/178:55 pmMEM - MYR
2 stops15h 56mSpirit Airlines
Deal found 10/27$343
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/111:54 pmMYR - GPT
1 stop4h 02mAmerican Airlines
Thu 11/134:54 pmGPT - MYR
1 stop4h 11mAmerican Airlines
Deal found 10/26$357
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/138:07 pmMYR - MEM
1 stop4h 52mAmerican Airlines
Tue 11/188:37 amMEM - MYR
1 stop5h 09mAmerican Airlines
Deal found 10/26$362
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1410:32 amMYR - GPT
1 stop4h 36mDelta
Wed 12/176:01 pmGPT - MYR
1 stop4h 42mDelta
Deal found 10/26$372
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/42:40 pmMYR - MOB
1 stop4h 52mDelta
Sun 12/77:17 pmMOB - MYR
1 stop3h 26mDelta
Deal found 10/27$387

Cheap flight deals from Myrtle Beach to Mississippi

Keep the following information in mind while searching for Myrtle Beach to Mississippi flight deals. Data was last updated October 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$268
(Mytrip)

One-way from

$174
(Delta)
Provider with most accurate pricing for Myrtle Beach Intl-Jackson-Evers Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Jackson-Evers Intl flights.
Search Deals
From Myrtle Beach Intl to Mississippi
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One-way flight from Myrtle Beach Intl to Mississippi
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Mississippi that are best for you.

Fly from

Myrtle Beach

Fly to

Mississippi

Route

Depart

Return

Price

Myrtle BeachMemphis

MYR - MEM

MYRMEM

Myrtle Beach Intl

Fri 12/12

2:15 pm-6:47 pm

1 stop5h 32m

Memphis

Mon 12/15

7:42 pm-5:48 pm

2 stops21h 06m

$268

Myrtle BeachMemphis

MYR - MEM

MYRMEM

Myrtle Beach Intl

Thu 12/11

6:56 pm-11:23 pm

1 stop5h 27m

Memphis

Thu 12/18

7:00 am-1:54 pm

1 stop5h 54m

$297

Myrtle BeachMemphis

MYR - MEM

MYRMEM

Myrtle Beach Intl

Tue 1/27

11:46 am-3:14 pm

3 stops28h 28m

Memphis

Fri 1/30

4:19 pm-10:41 am

2 stops17h 22m

$320

Myrtle BeachMemphis

MYR - MEM

MYRMEM

Myrtle Beach Intl

Tue 1/27

10:18 am-3:18 pm

1 stop6h 00m

Memphis

Fri 1/30

8:37 am-1:23 pm

1 stop3h 46m

$322

Myrtle BeachMemphis

MYR - MEM

MYRMEM

Myrtle Beach Intl

Thu 11/13

11:13 am-12:31 pm

2 stops26h 18m

Memphis

Mon 11/17

8:55 pm-1:51 pm

2 stops15h 56m

$322

Myrtle BeachMemphis

MYR - MEM

MYRMEM

Myrtle Beach Intl

Tue 1/27

11:05 am-1:55 pm

1 stop3h 50m

Memphis

Fri 1/30

6:40 am-7:45 pm

2 stops12h 05m

$327

Myrtle BeachMemphis

MYR - MEM

MYRMEM

Myrtle Beach Intl

Thu 11/27

6:15 am-10:03 am

1 stop4h 48m

Memphis

Mon 12/1

9:16 pm-11:54 pm

3 stops25h 38m

$331

Myrtle BeachMemphis

MYR - MEM

MYRMEM

Myrtle Beach Intl

Fri 2/6

10:33 am-4:16 pm

1 stop6h 43m

Memphis

Mon 2/9

11:57 am-6:02 pm

1 stop5h 05m

$332

Myrtle BeachGulfport

MYR - GPT

MYRGPT

Myrtle Beach Intl

Tue 11/11

1:54 pm-4:56 pm

1 stop4h 02m

Gulfport Biloxi Regional

Thu 11/13

4:54 pm-10:05 pm

1 stop4h 11m

$357

Myrtle BeachGulfport

MYR - GPT

MYRGPT

Myrtle Beach Intl

Sun 12/14

10:32 am-2:08 pm

1 stop4h 36m

Gulfport Biloxi Regional

Wed 12/17

6:01 pm-11:43 pm

1 stop4h 42m

$372

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 34 results
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Best time to book a flight from Myrtle Beach to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Mississippi

What is the cheapest month to book a flight from Myrtle Beach to Mississippi?

Currently, April is the cheapest month in which you can book a flight from Myrtle Beach to Mississippi (average of $165). Flying from Myrtle Beach to Mississippi in February is currently the most expensive (average of $323). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to MS?

Find hourly flight availability from Myrtle Beach to Mississippi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 28, 2025.

One of the essential ways to save on airfare from Myrtle Beach to Mississippi is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight at noon could potentially save you up to 35% on airfare.

Reviews of airlines servicing Mississippi

Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated October 28, 2025.
Peruse reviews from past customers who have flown with Delta and American Airlines from Myrtle Beach to Mississippi to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,994 reviews

Overall

7.9

Food

7.3

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,994 reviews
Delta
7.9
Good
7,994 reviews

Overall

7.9

Food

7.3

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,032 reviews
Delta
7.9
Good
7,994 reviews

Overall

7.9

Food

7.3

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to Mississippi?

    Located just 2.1 mi from the city center, Myrtle Beach Intl (MYR) is the airport most travelers will use when flying to Mississippi from Myrtle Beach.

  • How long is the flight from Myrtle Beach to Mississippi?

    Spirit Airlines, Delta, and American Airlines can get you from Myrtle Beach to Mississippi in just under 4h 02m. Your travel time can differ by up to 1h 30m. Myrtle Beach and Mississippi are separated by a distance of 635 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Myrtle Beach to Mississippi?

    The most popular route from Myrtle Beach to Mississippi is Myrtle Beach Intl - Memphis. You may also consider Myrtle Beach Intl - Mobile or Myrtle Beach Intl - Gulfport Biloxi Regional.

  • Can I find deals for flights from Myrtle Beach to Mississippi that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Mississippi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Mississippi.

  • Can I find deals for business class flights from Myrtle Beach to Mississippi?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Mississippi?

    Currently, April is the cheapest month in which you can book a flight from Myrtle Beach to Mississippi (average of $165). Flying from Myrtle Beach to Mississippi in February is currently the most expensive (average of $323). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Myrtle Beach to Mississippi

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Top 2 airlines flying from Myrtle Beach to Mississippi

Discover the top 2 airlines that operate flights from Myrtle Beach to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$327Average$422FlexibilityNo cancel feeOn-time71%
DeltaCheapest$358Average$406FlexibilityNo cancel feeOn-timeN/A

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