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$130+ Cheap flights from Myrtle Beach (MYR) to Mississippi

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/30. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — JAN
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Mississippi

Keep the following information in mind while searching for Myrtle Beach to Mississippi flight deals. Data was last updated September 11, 2025.

Round-trip from

$217
(Delta)

One-way from

$130
(American Airlines)
From Myrtle Beach Intl to Mississippi
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One-way flight from Myrtle Beach Intl to Mississippi
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Find flight deals from Myrtle Beach to Mississippi

Cheapest flights from Myrtle Beach to Mississippi
Explore the most affordable flight options available from Myrtle Beach to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/236:55 amMYR - JAN
1 stop11h 25mSouthwest
Tue 10/281:10 pmJAN - MYR
1 stop5h 35mSouthwest
Deal found 9/11$228
This Orbitz deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/25:20 pmMYR - MEM
1 stop7h 30mSpirit Airlines
Mon 10/67:00 amMEM - MYR
1 stop9h 44mSpirit Airlines
Deal found 9/10$229
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/26:55 amMYR - MEM
1 stop11h 20mSouthwest
Tue 10/72:45 pmMEM - MYR
1 stop4h 00mSouthwest
Deal found 9/10$230
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/34:33 pmMYR - MEM
1 stop6h 15mUnited Airlines
Tue 10/77:30 amMEM - MYR
1 stop6h 12mUnited Airlines
Deal found 9/10$242
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/312:45 pmMYR - MEM
2 stops9h 05mSouthwest
Tue 10/72:45 pmMEM - MYR
1 stop4h 00mSouthwest
Deal found 9/10$252
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/87:35 pmMYR - GPT
1 stop4h 11mAmerican Airlines
Wed 10/151:55 pmGPT - MYR
1 stop5h 52mAmerican Airlines
Deal found 9/11$297
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/26:55 amMYR - MEM
1 stop11h 20mSouthwest
Mon 10/611:35 amMEM - MYR
2 stops9h 45mSouthwest
Deal found 9/10$299
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/24:33 pmMYR - MEM
1 stop6h 15mUnited Airlines
Tue 10/77:30 amMEM - MYR
1 stop6h 12mUnited Airlines
Deal found 9/9$302
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/251:11 pmMYR - MEM
2 stops11h 39mSpirit Airlines
Mon 9/296:38 pmMEM - MYR
1 stop24h 28mSpirit Airlines
Deal found 9/9$304
This Priceline deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/267:17 pmMYR - MEM
1 stop5h 33mSpirit Airlines
Tue 9/307:00 amMEM - MYR
1 stop4h 29mSpirit Airlines
Deal found 9/11$309
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/258:20 pmMYR - GPT
1 stop4h 39mAmerican Airlines
Wed 10/295:45 pmGPT - MYR
1 stop4h 09mAmerican Airlines
Deal found 9/10$367
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/238:00 amMYR - JAN
2 stops15h 05mSouthwest
Sat 11/295:15 amJAN - MYR
2 stops11h 15mSouthwest
Deal found 9/9$413

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Mississippi that are best for you.

Fly from

Myrtle Beach

Fly to

Mississippi

Route

Depart

Return

Price

Myrtle BeachMemphis

MYR - MEM

MYRMEM

Myrtle Beach Intl

Tue 3/3

6:45 pm-10:52 pm

1 stop5h 07m

Memphis

Wed 3/4

6:00 am-10:08 am

1 stop3h 08m

$217

Myrtle BeachJackson

MYR - JAN

MYRJAN

Myrtle Beach Intl

Thu 10/23

6:55 am-5:20 pm

1 stop11h 25m

Jackson-Evers Intl

Tue 10/28

1:10 pm-7:45 pm

1 stop5h 35m

$228

Myrtle BeachMemphis

MYR - MEM

MYRMEM

Myrtle Beach Intl

Thu 10/2

5:20 pm-11:50 pm

1 stop7h 30m

Memphis

Mon 10/6

7:00 am-5:44 pm

1 stop9h 44m

$229

Myrtle BeachMemphis

MYR - MEM

MYRMEM

Myrtle Beach Intl

Thu 10/2

6:55 am-5:15 pm

1 stop11h 20m

Memphis

Tue 10/7

2:45 pm-7:45 pm

1 stop4h 00m

$230

Myrtle BeachMemphis

MYR - MEM

MYRMEM

Myrtle Beach Intl

Fri 10/3

12:45 pm-8:50 pm

2 stops9h 05m

Memphis

Tue 10/7

2:45 pm-7:45 pm

1 stop4h 00m

$252

Myrtle BeachGulfport

MYR - GPT

MYRGPT

Myrtle Beach Intl

Wed 10/8

7:35 pm-10:46 pm

1 stop4h 11m

Gulfport Biloxi Regional

Wed 10/15

1:55 pm-8:47 pm

1 stop5h 52m

$297

Myrtle BeachMemphis

MYR - MEM

MYRMEM

Myrtle Beach Intl

Thu 10/2

4:33 pm-9:48 pm

1 stop6h 15m

Memphis

Tue 10/7

7:30 am-2:42 pm

1 stop6h 12m

$302

Myrtle BeachMemphis

MYR - MEM

MYRMEM

Myrtle Beach Intl

Thu 9/25

1:11 pm-11:50 pm

2 stops11h 39m

Memphis

Mon 9/29

6:38 pm-8:06 pm

1 stop24h 28m

$304

Myrtle BeachMemphis

MYR - MEM

MYRMEM

Myrtle Beach Intl

Fri 9/26

7:17 pm-11:50 pm

1 stop5h 33m

Memphis

Tue 9/30

7:00 am-12:29 pm

1 stop4h 29m

$309

Myrtle BeachMemphis

MYR - MEM

MYRMEM

Myrtle Beach Intl

Thu 10/2

12:45 pm-10:35 pm

2 stops10h 50m

Memphis

Mon 10/6

11:35 am-10:20 pm

2 stops9h 45m

$354

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 32 results
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Best time to book a flight from Myrtle Beach to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Mississippi

What is the cheapest month to book a flight from Myrtle Beach to Mississippi?

Currently, January is the cheapest month in which you can book a flight from Myrtle Beach to Mississippi (average of $371). Flying from Myrtle Beach to Mississippi in March is currently the most expensive (average of $448). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to MS?

Find hourly flight availability from Myrtle Beach to Mississippi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

When flying from Myrtle Beach to Mississippi, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Mississippi

Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated September 11, 2025.
Peruse reviews from past customers who have flown with Delta and American Airlines from Myrtle Beach to Mississippi to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to Mississippi?

    Located just 2.1 mi from the city center, Myrtle Beach Intl (MYR) is the airport most travelers will use when flying to Mississippi from Myrtle Beach.

  • How long is the flight from Myrtle Beach to Mississippi?

    Delta, Southwest, and Spirit Airlines can get you from Myrtle Beach to Mississippi in just under 5h 07m. Your travel time can differ by up to 6h 18m. Myrtle Beach and Mississippi are separated by a distance of 637 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Myrtle Beach to Mississippi one-way?

    One-way options have recently been found by users for as low as $130 on American Airlines. Other airlines that offer cheap prices include Southwest from $189 and Spirit Airlines from $200 one-way.

  • What are the most popular routes from Myrtle Beach to Mississippi?

    The most popular route from Myrtle Beach to Mississippi is Myrtle Beach Intl - Memphis. You may also consider Myrtle Beach Intl - Mobile or Myrtle Beach Intl - Jackson-Evers Intl.

  • Can I find deals for flights from Myrtle Beach to Mississippi that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Mississippi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Mississippi.

  • Can I find deals for business class flights from Myrtle Beach to Mississippi?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Mississippi?

    Currently, January is the cheapest month in which you can book a flight from Myrtle Beach to Mississippi (average of $371). Flying from Myrtle Beach to Mississippi in March is currently the most expensive (average of $448). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Myrtle Beach to Mississippi

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Myrtle Beach to Mississippi

Discover the top 2 airlines that operate flights from Myrtle Beach to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$327Average$403FlexibilityNo cancel feeOn-time71%
DeltaCheapest$358Average$406FlexibilityNo cancel feeOn-timeN/A

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