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Mississippi

$66+ Cheap flights from Missouri to Mississippi

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel.
STL — JAN
Dec 6 — Dec 131
Sat 12/6
Sat 12/13
1 adult, Economy
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Cheap flight deals from Missouri to Mississippi

Keep the following information in mind while searching for Missouri to Mississippi flight deals. Data was last updated November 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$212
(Kiwi.com)

One-way from

$66
(Booking.com)

Popular in

February

Cheapest in

August

Average price

$476
Provider with most accurate pricing for Lambert-St Louis-Jackson-Evers Intl flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-Jackson-Evers Intl flights.
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From Missouri to Mississippi
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One-way flight from Missouri to Mississippi
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Highest demand for flights based on searches. 13% potential increase in price ($58 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease ($27 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Missouri to Mississippi

Cheapest flights from Missouri to Mississippi
Explore the most affordable flight options available from Missouri to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/107:43 pmSTL - MEM
2 stops16h 23mMultiple Airlines
Thu 12/117:42 pmMEM - STL
1 stop13h 17mMultiple Airlines
Deal found 11/6$212
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2110:10 pmSTL - MEM
1 stop22h 17mMultiple Airlines
Sun 12/288:17 pmMEM - STL
1 stop13h 28mMultiple Airlines
Deal found 11/6$214
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/43:30 pmSTL - MEM
1 stop22h 56mMultiple Airlines
Sun 12/77:42 pmMEM - STL
1 stop13h 17mMultiple Airlines
Deal found 11/4$223
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/153:47 pmMCI - MEM
1 stop27h 00mSpirit Airlines
Mon 1/58:17 pmMEM - MCI
1 stop26h 42mSpirit Airlines
Deal found 11/5$235
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/209:54 pmSTL - MEM
2 stops11h 49mMultiple Airlines
Mon 11/249:22 pmMEM - STL
1 stop23h 47mMultiple Airlines
Deal found 11/5$238
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/197:24 pmSTL - MEM
1 stop14h 39mMultiple Airlines
Sun 11/237:59 pmMEM - STL
1 stop14h 03mMultiple Airlines
Deal found 11/4$244
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/29:30 amSTL - GPT
1 stop4h 38mDelta
Sat 12/63:30 pmGPT - STL
1 stop6h 27mDelta
Deal found 11/5$249
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/263:00 pmMCI - BTR
1 stop4h 27mUnited Airlines
Fri 11/289:30 amBTR - MCI
1 stop4h 43mUnited Airlines
Deal found 11/4$249
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:15 amSTL - MOB
1 stop5h 24mUnited Airlines
Wed 12/104:55 pmMOB - STL
1 stop5h 03mUnited Airlines
Deal found 11/3$249
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/47:05 amSTL - BTR
1 stop6h 31mDelta
Sun 12/76:07 amBTR - STL
1 stop4h 38mDelta
Deal found 11/6$249
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/43:47 pmMCI - MEM
1 stop27h 00mSpirit Airlines
Thu 1/811:14 amMEM - MCI
1 stop28h 19mSpirit Airlines
Deal found 11/5$254
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/131:43 pmSTL - GPT
2 stops10h 10mAmerican Airlines
Tue 12/165:17 amGPT - STL
1 stop7h 15mAmerican Airlines
Deal found 11/5$254

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Missouri to Mississippi that are best for you.

Fly from

Missouri

Fly to

Mississippi

Route

Depart

Return

Price

St. LouisMemphis

STL - MEM

STLMEM

Lambert-St Louis

Sun 12/21

10:10 pm-8:27 pm

1 stop22h 17m

Memphis

Sun 12/28

8:17 pm-9:45 am

1 stop13h 28m

$214

St. LouisMemphis

STL - MEM

STLMEM

Lambert-St Louis

Thu 12/4

3:30 pm-2:26 pm

1 stop22h 56m

Memphis

Sun 12/7

7:42 pm-8:59 am

1 stop13h 17m

$223

Kansas CityMemphis

MCI - MEM

MCIMEM

Kansas City

Mon 12/15

3:47 pm-6:47 pm

1 stop27h 00m

Memphis

Mon 1/5

8:17 pm-10:59 pm

1 stop26h 42m

$235

St. LouisMemphis

STL - MEM

STLMEM

Lambert-St Louis

Thu 11/20

9:54 pm-9:43 am

2 stops11h 49m

Memphis

Mon 11/24

9:22 pm-9:09 pm

1 stop23h 47m

$238

St. LouisMemphis

STL - MEM

STLMEM

Lambert-St Louis

Wed 11/19

7:24 pm-10:03 am

1 stop14h 39m

Memphis

Sun 11/23

7:59 pm-10:02 am

1 stop14h 03m

$244

St. LouisGulfport

STL - GPT

STLGPT

Lambert-St Louis

Sat 1/24

7:10 am-2:13 pm

1 stop7h 03m

Gulfport Biloxi Regional

Wed 1/28

10:21 am-4:07 pm

1 stop5h 46m

$249

St. LouisGulfport

STL - GPT

STLGPT

Lambert-St Louis

Sat 12/13

5:30 pm-11:32 pm

1 stop6h 02m

Gulfport Biloxi Regional

Tue 12/16

1:02 pm-7:29 pm

1 stop6h 27m

$249

St. LouisMobile

STL - MOB

STLMOB

Lambert-St Louis

Wed 12/3

6:15 am-11:39 am

1 stop5h 24m

Mobile

Wed 12/10

4:55 pm-9:58 pm

1 stop5h 03m

$249

St. LouisGulfport

STL - GPT

STLGPT

Lambert-St Louis

Sat 1/17

9:59 am-3:11 pm

1 stop5h 12m

Gulfport Biloxi Regional

Wed 1/21

10:21 am-4:07 pm

1 stop5h 46m

$249

St. LouisMobile

STL - MOB

STLMOB

Lambert-St Louis

Sat 12/6

4:45 pm-9:47 pm

1 stop5h 02m

Mobile

Wed 12/10

4:55 pm-9:58 pm

1 stop5h 03m

$249

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/5

Showing 1-10 of 60 results
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Best time to book a flight from Missouri to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Mississippi

What is the cheapest month to book a flight from Missouri to Mississippi?

Currently, October is the cheapest month in which you can book a flight from Missouri to Mississippi (average of $120). Flying from Missouri to Mississippi in December is currently the most expensive (average of $278). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to MS?

Find hourly flight availability from Missouri to Mississippi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 6, 2025.

When flying from Missouri to Mississippi, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 24% versus a flight in the afternoon.

Reviews of airlines servicing Mississippi

Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated November 6, 2025.
See what other customers who have flown with Southwest, Delta, and United Airlines from Missouri to Mississippi have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,241 reviews

Overall

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,241 reviews
Southwest
8.0
Very good
4,241 reviews

Overall

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
8,001 reviews
Southwest
8.0
Very good
4,241 reviews

Overall

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
9,007 reviews
Southwest
8.0
Very good
4,241 reviews

Overall

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,040 reviews
Southwest
8.0
Very good
4,241 reviews

Overall

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Missouri to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Mississippi?

    Spirit Airlines, Delta, and American Airlines can get you from Missouri to Mississippi in just under 6h 02m. Your travel time can differ by up to 20h 58m. The distance from Missouri to Mississippi is about 581 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Missouri to Mississippi one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $66. Users have also found prices from $146 and $155 on Delta and American Airlines, respectively.

  • Can I find deals for flights from Missouri to Mississippi that include hotel bookings?

    Yes. In addition to deals on Missouri to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Mississippi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Mississippi.

  • Can I find deals for business class flights from Missouri to Mississippi?

    Yes. Cheapflights offers flight deals from Missouri to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Mississippi?

    Currently, October is the cheapest month in which you can book a flight from Missouri to Mississippi (average of $120). Flying from Missouri to Mississippi in December is currently the most expensive (average of $278). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Missouri to Mississippi

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Missouri to Mississippi

Discover the top 4 airlines that operate flights from Missouri to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$207Average$441FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$341FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$248Average$365FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$276Average$466FlexibilityNo cancel feeOn-time63%

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