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$113+ Cheap flights from South Carolina to Milwaukee (MKE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/13. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MKE
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from South Carolina to Milwaukee

Keep the following information in mind while searching for South Carolina to Milwaukee flight deals. Data was last updated September 16, 2025.

Round-trip from

$238
(American Airlines)

One-way from

$113
(Kiwi.com)

Popular in

July

Cheapest in

April

Average price

$318
From South Carolina to Milwaukee-Mitchell
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One-way flight from South Carolina to Milwaukee-Mitchell
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Highest demand for flights based on searches. 9% potential increase in price ($35 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from South Carolina to Milwaukee

Cheapest flights from South Carolina to Milwaukee
Explore the most affordable flight options available from South Carolina to Milwaukee. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1511:07 amSAV - MKE
1 stop13h 23mAmerican Airlines
Wed 10/223:06 pmMKE - SAV
1 stop6h 57mAmerican Airlines
Deal found 9/15$238
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/117:12 pmSAV - MKE
1 stop4h 25mAmerican Airlines
Tue 10/1412:20 pmMKE - SAV
1 stop8h 16mAmerican Airlines
Deal found 9/14$248
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/55:24 pmCAE - MKE
1 stop6h 19mUnited Airlines
Sat 11/88:44 amMKE - CAE
1 stop4h 03mUnited Airlines
Deal found 9/16$249
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/62:56 pmSAV - MKE
2 stops9h 09mAmerican Airlines
Mon 12/86:01 amMKE - SAV
1 stop14h 43mAmerican Airlines
Deal found 9/15$253
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/57:12 pmCAE - MKE
1 stop4h 44mAmerican Airlines
Sat 11/88:05 amMKE - CAE
2 stops8h 43mAmerican Airlines
Deal found 9/16$254
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/236:45 amCLT - MKE
1 stop5h 16mDelta
Sun 10/266:44 pmMKE - CLT
1 stop4h 06mDelta
Deal found 9/15$257
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/15:26 pmCAE - MKE
1 stop4h 20mUnited Airlines
Sun 10/55:00 amMKE - CAE
1 stop4h 25mUnited Airlines
Deal found 9/16$259
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/111:15 pmSAV - MKE
1 stop4h 51mUnited Airlines
Tue 10/146:00 amMKE - SAV
1 stop5h 09mUnited Airlines
Deal found 9/15$267
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/245:19 pmSAV - MKE
1 stop6h 57mAmerican Airlines
Mon 10/277:12 amMKE - SAV
1 stop6h 10mAmerican Airlines
Deal found 9/14$277
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/305:30 amCLT - MKE
1 stop4h 56mDelta
Thu 11/69:39 amMKE - CLT
1 stop5h 16mDelta
Deal found 9/15$277
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/236:00 amCAE - MKE
1 stop7h 23mDelta
Sun 9/285:40 amMKE - CAE
1 stop3h 37mDelta
Deal found 9/15$284
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2312:14 pmHHH - MKE
1 stop5h 00mDelta
Tue 9/3010:29 amMKE - HHH
1 stop3h 56mDelta
Deal found 9/15$284

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Milwaukee that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from South Carolina to Milwaukee that are best for you.

Fly from

South Carolina

Fly to

Milwaukee

Route

Depart

Return

Price

SavannahMilwaukee

SAV - MKE

SAVMKE

Savannah/Hilton Head

Wed 10/15

11:07 am-11:30 pm

1 stop13h 23m

Milwaukee-Mitchell

Wed 10/22

6:00 am-3:06 pm

2 stops8h 06m

$243

SavannahMilwaukee

SAV - MKE

SAVMKE

Savannah/Hilton Head

Sat 12/6

6:06 pm-12:01 am

1 stop6h 55m

Milwaukee-Mitchell

Mon 12/8

6:01 am-9:44 pm

1 stop14h 43m

$248

SavannahMilwaukee

SAV - MKE

SAVMKE

Savannah/Hilton Head

Sat 10/11

7:12 pm-10:37 pm

1 stop4h 25m

Milwaukee-Mitchell

Tue 10/14

12:20 pm-9:36 pm

1 stop8h 16m

$248

ColumbiaMilwaukee

CAE - MKE

CAEMKE

Columbia Metropolitan

Sat 2/21

10:10 am-4:17 pm

1 stop7h 07m

Milwaukee-Mitchell

Wed 2/25

7:00 am-2:11 pm

1 stop6h 11m

$249

ColumbiaMilwaukee

CAE - MKE

CAEMKE

Columbia Metropolitan

Wed 11/5

5:24 pm-10:43 pm

1 stop6h 19m

Milwaukee-Mitchell

Sat 11/8

8:44 am-1:47 pm

1 stop4h 03m

$249

CharlotteMilwaukee

CLT - MKE

CLTMKE

Charlotte Douglas

Sat 12/13

7:30 am-10:43 am

1 stop4h 13m

Milwaukee-Mitchell

Fri 1/2

3:26 pm-10:10 pm

1 stop5h 44m

$257

CharlotteMilwaukee

CLT - MKE

CLTMKE

Charlotte Douglas

Fri 10/24

7:30 pm-11:55 pm

1 stop5h 25m

Milwaukee-Mitchell

Sun 10/26

6:44 pm-11:50 pm

1 stop4h 06m

$257

ColumbiaMilwaukee

CAE - MKE

CAEMKE

Columbia Metropolitan

Wed 10/1

5:26 pm-8:46 pm

1 stop4h 20m

Milwaukee-Mitchell

Sun 10/5

5:00 am-10:25 am

1 stop4h 25m

$259

SavannahMilwaukee

SAV - MKE

SAVMKE

Savannah/Hilton Head

Wed 10/15

2:10 pm-10:00 pm

2 stops8h 50m

Milwaukee-Mitchell

Wed 10/22

7:35 am-8:05 pm

2 stops11h 30m

$267

SavannahMilwaukee

SAV - MKE

SAVMKE

Savannah/Hilton Head

Sat 10/11

1:15 pm-5:06 pm

1 stop4h 51m

Milwaukee-Mitchell

Tue 10/14

6:00 am-12:09 pm

1 stop5h 09m

$267

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Milwaukee

Have a flexible travel schedule? Discover the best time to fly to Milwaukee from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Milwaukee

What is the cheapest month to book a flight from South Carolina to Milwaukee?

Currently, February is the cheapest month in which you can book a flight from South Carolina to Milwaukee (average of $280). Flying from South Carolina to Milwaukee in June is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to MKE?

Find hourly flight availability from South Carolina to Milwaukee. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

When flying from South Carolina to Milwaukee, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Milwaukee. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Milwaukee from South Carolina?

    For a flight from South Carolina to Milwaukee, you will be flying into Milwaukee-Mitchell. Milwaukee-Mitchell (MKE) is just 6.4 mi from the center of the city.

  • How long is the flight from South Carolina to Milwaukee?

    For as low as $249, American Airlines can have you in Milwaukee from South Carolina in 6h 19m. South Carolina and Milwaukee are separated by a distance of 721 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from South Carolina to Milwaukee one-way?

    The cheapest airlines for a one-way flight from South Carolina to Milwaukee are Frontier ($113), JetBlue ($120), and Delta ($129).

  • What are the most popular routes from South Carolina to Milwaukee?

    The most popular flight routes from South Carolina to Milwaukee are Charlotte Douglas - Milwaukee-Mitchell, Charleston - Milwaukee-Mitchell and Greenville - Milwaukee-Mitchell.

  • Can I find deals for flights from South Carolina to Milwaukee that include hotel bookings?

    Yes. In addition to deals on South Carolina to Milwaukee flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Milwaukee?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Milwaukee.

  • Can I find deals for business class flights from South Carolina to Milwaukee?

    Yes. Cheapflights offers flight deals from South Carolina to Milwaukee by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Milwaukee?

    Currently, February is the cheapest month in which you can book a flight from South Carolina to Milwaukee (average of $280). Flying from South Carolina to Milwaukee in June is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Milwaukee?

Book flights to Milwaukee if you plan to visit one of these locations
Sheboygan
Oak Creek
New Berlin
Wauwatosa

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Alternative routes for South Carolina to Milwaukee

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from South Carolina to Milwaukee

Discover the top 4 airlines that operate flights from South Carolina to Milwaukee. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$168Average$398FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$216Average$466FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$228Average$384FlexibilityNo cancel feeOn-time69%
DeltaCheapest$228Average$362FlexibilityNo cancel feeOn-timeN/A

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