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$89+ Cheap flights from South Carolina to Milwaukee (MKE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/29. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MKE
nov. 29 — dic. 61
sáb. 11/29
sáb. 12/6
1 adult, Economy
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Find flight deals from South Carolina to Milwaukee

Cheapest flights from South Carolina to Milwaukee
Explore the most affordable flight options available from South Carolina to Milwaukee. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 30, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/112:59 pmCHS - MKE
1 stop19h 40mMultiple Airlines
lun. 12/1510:34 amMKE - CHS
1 stop21h 03mMultiple Airlines
Deal found 10/28$221
This Mytrip deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/1012:59 pmCLT - MKE
2 stops21h 40mSpirit Airlines
vie. 12/1210:34 amMKE - CLT
1 stop8h 26mSpirit Airlines
Deal found 10/29$236
This Mytrip deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/68:55 pmCLT - MKE
1 stop13h 44mSpirit Airlines
lun. 12/810:34 amMKE - CLT
1 stop8h 26mSpirit Airlines
Deal found 10/30$241
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/57:00 amCLT - MKE
2 stops11h 09mMultiple Airlines
dom. 12/76:09 pmMKE - CLT
1 stop24h 51mMultiple Airlines
Deal found 10/29$247
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/115:34 amCAE - MKE
1 stop4h 54mDelta
dom. 12/147:00 amMKE - CAE
1 stop6h 03mDelta
Deal found 10/29$249
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/127:00 amCLT - MKE
2 stops11h 09mMultiple Airlines
dom. 12/146:09 pmMKE - CLT
1 stop14h 28mMultiple Airlines
Deal found 10/30$250
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/1211:03 amCAE - MKE
1 stop4h 10mDelta
mié. 11/191:19 pmMKE - CAE
1 stop5h 59mDelta
Deal found 10/28$254
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/127:00 amCLT - MKE
2 stops11h 09mMultiple Airlines
lun. 12/1510:34 amMKE - CLT
1 stop8h 26mMultiple Airlines
Deal found 10/30$255
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/1112:56 pmCAE - MKE
1 stop4h 21mDelta
sáb. 11/157:00 amMKE - CAE
1 stop4h 06mDelta
Deal found 10/28$259
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/139:57 amCLT - MKE
2 stops34h 22mMultiple Airlines
dom. 11/167:03 pmMKE - CLT
1 stop12h 59mMultiple Airlines
Deal found 10/30$262
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/279:02 pmCLT - MKE
1 stop23h 18mMultiple Airlines
sáb. 1/37:48 pmMKE - CLT
1 stop23h 51mMultiple Airlines
Deal found 10/29$274
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/135:37 amCAE - MKE
1 stop4h 44mDelta
lun. 11/1710:56 amMKE - CAE
1 stop8h 22mDelta
Deal found 10/29$279

Cheap flight deals from South Carolina to Milwaukee

Keep the following information in mind while searching for South Carolina to Milwaukee flight deals. Data was last updated octubre 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$221
(Kiwi.com)

One-way from

$89
(Trip.com)

Popular in

July

Cheapest in

October

Average price

$218
Provider with most accurate pricing for Myrtle Beach Intl-Milwaukee-Mitchell flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Milwaukee-Mitchell flights.
Search Deals
From South Carolina to Milwaukee-Mitchell
Search Deals
One-way flight from South Carolina to Milwaukee-Mitchell
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($50 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Milwaukee that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 30, 2025.
Use the filters below to find and compare flights from South Carolina to Milwaukee that are best for you.

Fly from

South Carolina

Fly to

Milwaukee

Route

Depart

Return

Price

CharlotteMilwaukee

CLT - MKE

CLTMKE

Charlotte Douglas

vie. 1/9

1:08 pm-6:45 pm

1 stop6h 37m

Milwaukee-Mitchell

dom. 1/11

7:40 pm-7:57 am

1 stop11h 17m

$195

CharlotteMilwaukee

CLT - MKE

CLTMKE

Charlotte Douglas

vie. 12/5

7:00 am-5:09 pm

2 stops11h 09m

Milwaukee-Mitchell

dom. 12/7

6:09 pm-8:00 pm

1 stop24h 51m

$247

ColumbiaMilwaukee

CAE - MKE

CAEMKE

Columbia Metropolitan

mié. 2/18

7:00 am-12:18 pm

1 stop6h 18m

Milwaukee-Mitchell

sáb. 2/21

1:20 pm-8:44 pm

1 stop6h 24m

$249

ColumbiaMilwaukee

CAE - MKE

CAEMKE

Columbia Metropolitan

mié. 1/7

7:00 am-1:13 pm

1 stop7h 13m

Milwaukee-Mitchell

mié. 1/14

5:20 am-12:00 pm

1 stop5h 40m

$249

ColumbiaMilwaukee

CAE - MKE

CAEMKE

Columbia Metropolitan

mié. 1/7

6:18 am-12:21 pm

2 stops7h 03m

Milwaukee-Mitchell

mié. 1/14

4:05 pm-8:53 pm

1 stop3h 48m

$254

ColumbiaMilwaukee

CAE - MKE

CAEMKE

Columbia Metropolitan

sáb. 11/15

5:44 pm-11:41 pm

1 stop6h 57m

Milwaukee-Mitchell

mié. 11/19

7:00 am-12:06 pm

1 stop4h 06m

$254

ColumbiaMilwaukee

CAE - MKE

CAEMKE

Columbia Metropolitan

jue. 11/13

7:50 pm-11:55 pm

1 stop5h 05m

Milwaukee-Mitchell

jue. 11/20

11:37 am-4:54 pm

1 stop4h 17m

$254

ColumbiaMilwaukee

CAE - MKE

CAEMKE

Columbia Metropolitan

jue. 11/13

5:37 am-9:21 am

1 stop4h 44m

Milwaukee-Mitchell

mar. 11/18

7:00 am-12:06 pm

1 stop4h 06m

$254

ColumbiaMilwaukee

CAE - MKE

CAEMKE

Columbia Metropolitan

mar. 11/11

5:00 pm-9:45 pm

1 stop5h 45m

Milwaukee-Mitchell

mar. 11/18

1:19 pm-8:18 pm

1 stop5h 59m

$254

ColumbiaMilwaukee

CAE - MKE

CAEMKE

Columbia Metropolitan

vie. 11/14

5:00 pm-9:45 pm

1 stop5h 45m

Milwaukee-Mitchell

mar. 11/18

5:45 am-12:06 pm

1 stop5h 21m

$254

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/30

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Milwaukee

Have a flexible travel schedule? Discover the best time to fly to Milwaukee from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Milwaukee

What is the cheapest month to book a flight from South Carolina to Milwaukee?

Currently, June is the cheapest month in which you can book a flight from South Carolina to Milwaukee (average of $98). Flying from South Carolina to Milwaukee in February is currently the most expensive (average of $200). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to MKE?

Find hourly flight availability from South Carolina to Milwaukee. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated octubre 30, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 15% on flights from South Carolina to Milwaukee by exploring options for tickets in the afternoon.

What is the cheapest day to fly from South Carolina to Milwaukee?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Milwaukee. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their South Carolina to Milwaukee flight should consider departing on Saturday mornings when fares are most often at their lowest. Monday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Milwaukee. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Milwaukee from South Carolina?

    For a flight from South Carolina to Milwaukee, you will be flying into Milwaukee-Mitchell. Milwaukee-Mitchell (MKE) is just 6.4 mi from the center of the city.

  • How long is the flight from South Carolina to Milwaukee?

    For as low as $249, Frontier can have you in Milwaukee from South Carolina in 6h 18m. South Carolina and Milwaukee are separated by a distance of 721 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from South Carolina to Milwaukee one-way?

    The cheapest airlines for a one-way flight from South Carolina to Milwaukee are Spirit Airlines ($132), Frontier ($138), and Delta ($157).

  • What are the most popular routes from South Carolina to Milwaukee?

    The most popular flight routes from South Carolina to Milwaukee are Charlotte Douglas - Milwaukee-Mitchell, Greenville - Milwaukee-Mitchell and Charleston - Milwaukee-Mitchell.

  • Can I find deals for flights from South Carolina to Milwaukee that include hotel bookings?

    Yes. In addition to deals on South Carolina to Milwaukee flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Milwaukee?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Milwaukee.

  • Can I find deals for business class flights from South Carolina to Milwaukee?

    Yes. Cheapflights offers flight deals from South Carolina to Milwaukee by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Milwaukee?

    Currently, June is the cheapest month in which you can book a flight from South Carolina to Milwaukee (average of $98). Flying from South Carolina to Milwaukee in February is currently the most expensive (average of $200). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Milwaukee?

Book flights to Milwaukee if you plan to visit one of these locations
Sheboygan
New Berlin
Oak Creek
Wauwatosa

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Milwaukee

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from South Carolina to Milwaukee

Discover the top 4 airlines that operate flights from South Carolina to Milwaukee. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$168Average$409FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$216Average$460FlexibilityNo cancel feeOn-time63%
DeltaCheapest$228Average$355FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$266Average$400FlexibilityNo cancel feeOn-time69%

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