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$87+ Cheap flights from South Carolina to Milwaukee (MKE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/23. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MKE
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from South Carolina to Milwaukee

Cheapest flights from South Carolina to Milwaukee
Explore the most affordable flight options available from South Carolina to Milwaukee. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/251:20 pmSAV - MKE
1 stop5h 26mAmerican Airlines
Thu 1/16:27 pmMKE - SAV
1 stop4h 46mAmerican Airlines
Deal found 12/16$269
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/252:25 pmSAV - MKE
2 stops7h 46mUnited Airlines
Thu 1/16:36 amMKE - SAV
2 stops7h 08mUnited Airlines
Deal found 12/16$314
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2411:20 amCLT - MKE
1 stop7h 29mAmerican Airlines
Wed 12/317:45 amMKE - CLT
1 stop10h 25mAmerican Airlines
Deal found 12/17$348
This Kiwi.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/249:34 pmCLT - MKE
1 stop22h 46mSpirit Airlines
Wed 12/318:15 pmMKE - CLT
2 stops26h 14mSpirit Airlines
Deal found 12/17$360
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:52 pmCLT - MKE
1 stop9h 08mAmerican Airlines
Sat 1/37:10 amMKE - CLT
Nonstop2h 11mAmerican Airlines
Deal found 12/17$407
This Orbitz deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:00 amCLT - MKE
2 stops11h 20mMultiple Airlines
Fri 1/26:16 pmMKE - CLT
1 stop24h 53mMultiple Airlines
Deal found 12/16$409
This American Airlines deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/207:59 pmCAE - MKE
1 stop5h 00mAmerican Airlines
Sat 1/36:02 amMKE - CAE
2 stops7h 08mAmerican Airlines
Deal found 12/18$428
This Southwest deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:10 pmCLT - MKE
1 stop4h 10mSouthwest
Fri 1/25:00 amMKE - CLT
1 stop6h 10mSouthwest
Deal found 12/16$429
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/309:00 amCLT - MKE
2 stops10h 26mMultiple Airlines
Sat 1/38:15 pmMKE - CLT
1 stop23h 23mMultiple Airlines
Deal found 12/16$449
This Kiwi.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:00 amCLT - MKE
2 stops13h 20mSpirit Airlines
Sat 1/38:15 pmMKE - CLT
1 stop23h 24mSpirit Airlines
Deal found 12/17$471
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/186:16 pmAGS - MKE
1 stop6h 42mAmerican Airlines
Sat 12/2010:59 amMKE - AGS
1 stop5h 47mAmerican Airlines
Deal found 12/16$506
This Kiwi.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1811:33 amGSP - MKE
1 stop8h 47mMultiple Airlines
Tue 12/308:15 pmMKE - GSP
2 stops18h 40mMultiple Airlines
Deal found 12/15$568

Find flight deals from South Carolina to Milwaukee

Keep the following information in mind while searching for South Carolina to Milwaukee flight deals. Data was last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$234
(Kiwi.com)

One-way from

$87
(Expedia)

Popular in

July

Cheapest in

May

Average price

$363
Provider with most accurate pricing for Myrtle Beach Intl-Milwaukee-Mitchell flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Milwaukee-Mitchell flights.
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From South Carolina to Milwaukee-Mitchell
Search Deals
One-way flight from South Carolina to Milwaukee-Mitchell
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($53 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Milwaukee that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from South Carolina to Milwaukee that are best for you.

Fly from

South Carolina

Fly to

Milwaukee

Route

Depart

Return

Price

ColumbiaMilwaukee

CAE - MKE

CAEMKE

Columbia Metropolitan

Sat 1/17

2:49 pm-10:56 pm

2 stops9h 07m

Milwaukee-Mitchell

Sat 1/24

6:00 am-2:00 pm

1 stop7h 00m

$264

ColumbiaMilwaukee

CAE - MKE

CAEMKE

Columbia Metropolitan

Wed 1/7

7:10 pm-11:23 pm

1 stop5h 13m

Milwaukee-Mitchell

Wed 1/14

6:06 am-11:34 am

1 stop4h 28m

$269

Hilton Head IslandMilwaukee

HHH - MKE

HHHMKE

Hilton Head Island

Sat 2/21

6:22 pm-10:53 pm

1 stop5h 31m

Milwaukee-Mitchell

Sat 2/28

7:00 am-2:27 pm

1 stop6h 27m

$283

Myrtle BeachMilwaukee

MYR - MKE

MYRMKE

Myrtle Beach Intl

Wed 1/14

7:19 pm-11:23 pm

1 stop5h 04m

Milwaukee-Mitchell

Sat 1/17

4:05 pm-8:54 pm

1 stop3h 49m

$290

ColumbiaMilwaukee

CAE - MKE

CAEMKE

Columbia Metropolitan

Sat 1/17

12:45 pm-4:27 pm

1 stop4h 42m

Milwaukee-Mitchell

Wed 1/21

10:15 am-4:18 pm

1 stop5h 03m

$291

ColumbiaMilwaukee

CAE - MKE

CAEMKE

Columbia Metropolitan

Thu 1/15

10:15 am-1:37 pm

1 stop4h 22m

Milwaukee-Mitchell

Sun 1/25

3:42 pm-11:45 pm

1 stop7h 03m

$291

ColumbiaMilwaukee

CAE - MKE

CAEMKE

Columbia Metropolitan

Sat 1/17

12:45 pm-4:27 pm

1 stop4h 42m

Milwaukee-Mitchell

Tue 1/27

7:00 am-11:58 am

1 stop3h 58m

$291

ColumbiaMilwaukee

CAE - MKE

CAEMKE

Columbia Metropolitan

Sun 3/29

7:00 am-11:03 am

1 stop5h 03m

Milwaukee-Mitchell

Sat 4/4

1:15 pm-6:08 pm

1 stop3h 53m

$291

ColumbiaMilwaukee

CAE - MKE

CAEMKE

Columbia Metropolitan

Wed 1/14

5:09 pm-7:58 pm

1 stop3h 49m

Milwaukee-Mitchell

Sun 1/25

10:13 am-6:10 pm

1 stop6h 57m

$291

ColumbiaMilwaukee

CAE - MKE

CAEMKE

Columbia Metropolitan

Thu 1/15

10:15 am-4:29 pm

1 stop7h 14m

Milwaukee-Mitchell

Sat 1/24

6:21 pm-11:45 pm

1 stop4h 24m

$291

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/17

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Milwaukee

Have a flexible travel schedule? Discover the best time to fly to Milwaukee from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Milwaukee

What is the cheapest month to book a flight from South Carolina to Milwaukee?

Currently, June is the cheapest month in which you can book a flight from South Carolina to Milwaukee (average of $96). Flying from South Carolina to Milwaukee in February is currently the most expensive (average of $205). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to MKE?

Find hourly flight availability from South Carolina to Milwaukee. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 15% on flights from South Carolina to Milwaukee by exploring options for tickets in the afternoon.

What is the cheapest day to fly from South Carolina to Milwaukee?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Milwaukee. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their South Carolina to Milwaukee flight should consider departing on Saturday mornings when fares are most often at their lowest. Monday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Milwaukee. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Milwaukee from South Carolina?

    For a flight from South Carolina to Milwaukee, you will be flying into Milwaukee-Mitchell. Milwaukee-Mitchell (MKE) is just 6.4 mi from the center of the city.

  • How long is the flight from South Carolina to Milwaukee?

    For as low as $311, United Airlines can have you in Milwaukee from South Carolina in 4h 35m. South Carolina and Milwaukee are separated by a distance of 634 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from South Carolina to Milwaukee one-way?

    The cheapest airlines for a one-way flight from South Carolina to Milwaukee are United Airlines ($172), Delta ($193), and Southwest ($198).

  • What are the most popular routes from South Carolina to Milwaukee?

    The most popular flight routes from South Carolina to Milwaukee are Charlotte Douglas - Milwaukee-Mitchell, Charleston - Milwaukee-Mitchell and Myrtle Beach Intl - Milwaukee-Mitchell.

  • Can I find deals for flights from South Carolina to Milwaukee that include hotel bookings?

    Yes. In addition to deals on South Carolina to Milwaukee flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Milwaukee?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Milwaukee.

  • Can I find deals for business class flights from South Carolina to Milwaukee?

    Yes. Cheapflights offers flight deals from South Carolina to Milwaukee by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Milwaukee?

    Currently, June is the cheapest month in which you can book a flight from South Carolina to Milwaukee (average of $96). Flying from South Carolina to Milwaukee in February is currently the most expensive (average of $205). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Milwaukee?

Book flights to Milwaukee if you plan to visit one of these locations
Sheboygan
New Berlin
Oak Creek
Wauwatosa

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Alternative routes for South Carolina to Milwaukee

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from South Carolina to Milwaukee

Discover the top 4 airlines that operate flights from South Carolina to Milwaukee. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$168Average$390FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$216Average$406FlexibilityNo cancel feeOn-time63%
DeltaCheapest$228Average$352FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$266Average$414FlexibilityNo cancel feeOn-time69%

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