
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $697 (Air Europa) |
One-way from | $429 (Kiwi.com) |
Popular in | December |
Cheapest in | October |
Average price | $815 |
Fly from
Fly to
Route
Depart
Return
Price
Panama CityMilan
PTY - MXP
PTYMXP
Panama City Tocumen Intl
Sun 4/19
8:25 pm-9:45 am
1 stop30h 20m
Milan Malpensa
Mon 5/4
11:05 am-6:40 pm
1 stop14h 35m
Panama CityMilan
PTY - MXP
PTYMXP
Panama City Tocumen Intl
Wed 4/15
8:25 pm-5:15 pm
1 stop13h 50m
Milan Malpensa
Wed 4/29
11:05 am-6:40 pm
1 stop14h 35m
Panama CityMilan
PTY - MXP
PTYMXP
Panama City Tocumen Intl
Wed 2/18
9:45 pm-5:40 pm
1 stop37h 55m
Milan Malpensa
Wed 2/25
11:05 am-5:05 pm
2 stops36h 00m
Panama CityMilan
PTY - MXP
PTYMXP
Panama City Tocumen Intl
Sat 4/18
8:25 pm-5:15 pm
1 stop13h 50m
Milan Malpensa
Thu 4/30
11:05 am-6:40 pm
1 stop14h 35m
Panama CityMilan
PTY - MXP
PTYMXP
Panama City Tocumen Intl
Thu 4/2
8:25 pm-5:15 pm
1 stop13h 50m
Milan Malpensa
Mon 4/13
11:05 am-6:40 pm
1 stop14h 35m
Panama CityMilan
PTY - LIN
PTYLIN
Panama City Tocumen Intl
Thu 5/14
6:50 pm-10:05 am
1 stop32h 15m
Milan Linate
Sat 5/30
4:50 pm-4:50 pm
1 stop31h 00m
Panama CityMilan
PTY - MXP
PTYMXP
Panama City Tocumen Intl
Mon 5/18
8:25 pm-5:15 pm
1 stop13h 50m
Milan Malpensa
Fri 5/29
6:15 pm-6:40 pm
1 stop31h 25m
Panama CityMilan
PTY - MXP
PTYMXP
Panama City Tocumen Intl
Mon 3/2
9:45 pm-9:05 am
1 stop29h 20m
Milan Malpensa
Wed 3/11
2:30 pm-5:05 pm
2 stops32h 35m
Panama CityMilan
PTY - MXP
PTYMXP
Panama City Tocumen Intl
Sat 5/9
8:25 pm-5:15 pm
1 stop13h 50m
Milan Malpensa
Sun 5/31
11:05 am-6:40 pm
1 stop14h 35m
Panama CityMilan
PTY - MXP
PTYMXP
Panama City Tocumen Intl
Sun 5/3
8:25 pm-5:15 pm
1 stop13h 50m
Milan Malpensa
Wed 5/6
11:05 am-6:40 pm
1 stop14h 35m
The price you pay for your flight from Panama City to Milan may vary depending on when you book. For the best chance of a lower fare, look to book 33 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Currently, June is the cheapest month in which you can book a flight from Panama City to Milan (average of $383). Flying from Panama City to Milan in January is currently the most expensive (average of $876). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Frankfurt am Main (FRA) – chosen by Cheapflights users on 80% of 1-stop itineraries from Panama City to Milan on Cheapflights.
Frankfurt am Main (FRA) is the most affordable 1-stop option, with an average round-trip price of $921.
Flights via Istanbul (IST) have the shortest average one-way travel time for 1-stop routes: 16h 55m.
Flights via Istanbul (IST) offer the fastest connection on this route, with an average layover time of 1h 33m.
Boarding
Food
Overall
Entertainment
Comfort
Crew
Reviews
Jayesh,Jan 2026
CDG - NMI
Boarding
Food
Overall
Entertainment
Comfort
Crew
Reviews
Jayesh,Jan 2026
CDG - NMI
Boarding
Food
Overall
Entertainment
Comfort
Crew
Reviews
Jayesh,Jan 2026
CDG - NMI
Boarding
Food
Overall
Entertainment
Comfort
Crew
Reviews
Jayesh,Jan 2026
CDG - NMI
Boarding
Food
Overall
Entertainment
Comfort
Crew
Reviews
Jayesh,Jan 2026
CDG - NMI
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$678 | Average$969 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$742 | Average$1,331 | FlexibilityNo cancel fee | On-time83% | |
| Cheapest$783 | Average$884 | FlexibilityNo cancel fee | On-time77% |