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$539+ Cheap flights from Panama City (PTY) to Milan (MIL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/9. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — MIL
Jan 3 — Jan 101
Sat 1/3
Sat 1/10
1 adult, Economy
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Cheapflights Tip: The best prices from Panama City Tocumen Intl to Milan are usually found in October or May, booked 33 days in advance, depart on a Friday or Monday and return on a Tuesday

Cheap flight deals from Panama City to Milan

Cheapest flights from Panama City to Milan
Explore the most affordable flight options available from Panama City to Milan. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

This Air France deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3110:20 pmPTY - MXP
1 stop18h 40mAir France
Sat 1/316:25 pmMXP - PTY
1 stop31h 45mAir France
Deal found 12/3$807
This KLM deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:45 pmPTY - LIN
1 stop22h 10mKLM
Mon 1/266:30 amLIN - PTY
1 stop19h 25mKLM
Deal found 12/3$851
This Turkish Airlines deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/229:45 pmPTY - MXP
1 stop37h 55mTurkish Airlines
Mon 3/26:55 amMXP - PTY
2 stops40h 10mTurkish Airlines
Deal found 12/4$1,044
This Mytrip deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:05 pmPTY - MXP
1 stop20h 15mMultiple Airlines
Sun 1/115:10 pmMXP - PTY
3 stops26h 50mMultiple Airlines
Deal found 12/2$1,083
This SmartFares deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:05 pmPTY - MXP
1 stop20h 15mCondor
Sun 1/114:45 pmMXP - PTY
1 stop30h 00mCondor
Deal found 12/2$1,113
This KLM deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:45 pmPTY - LIN
1 stop22h 10mKLM
Sun 1/114:50 pmLIN - PTY
1 stop29h 40mKLM
Deal found 12/2$1,154
This Air France deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/73:46 pmPTY - MXP
1 stop35h 19mAir France
Wed 12/3112:35 pmMXP - PTY
1 stop13h 35mAir France
Deal found 12/4$1,198
This FlightHub deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:20 pmPTY - LIN
1 stop19h 20mIberia
Sat 1/3111:35 amLIN - PTY
2 stops31h 52mIberia
Deal found 12/3$1,276
This Orbitz deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2512:55 pmPTY - LIN
2 stops24h 45mIberia
Sun 1/1111:35 amLIN - PTY
2 stops31h 52mIberia
Deal found 12/2$1,281
This Kiwi.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:05 pmPTY - LIN
1 stop21h 40mMultiple Airlines
Sun 1/117:10 amLIN - PTY
2 stops18h 35mMultiple Airlines
Deal found 12/2$1,329
This Air France deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/510:20 pmPTY - MXP
1 stop18h 40mAir France
Thu 1/17:50 pmMXP - PTY
1 stop30h 20mAir France
Deal found 12/4$1,336
This Iberia deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/72:50 pmPTY - MXP
2 stops36h 55mIberia
Wed 12/317:10 pmMXP - PTY
2 stops31h 10mIberia
Deal found 12/3$1,350

Find flight deals from Panama City to Milan

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Milan (MIL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$702
(KLM)

One-way from

$539
(Kiwi.com)

Popular in

January

Cheapest in

October

Average price

$916
Provider with most accurate pricing for Panama City Tocumen Intl-Milan (MIL) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Milan (MIL) flights.
Search Deals
From Panama City Tocumen Intl to Milan (MIL)
Search Deals
One-way flight from Panama City Tocumen Intl to Milan (MIL)
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($73 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Milan that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from Panama City to Milan that are best for you.

Fly from

Panama City

Fly to

Milan

Route

Depart

Return

Price

Panama CityMilan

PTY - LIN

PTYLIN

Panama City Tocumen Intl

Mon 2/16

10:05 pm-10:55 pm

1 stop18h 50m

Milan Linate

Thu 2/26

6:30 am-4:30 pm

1 stop16h 00m

$702

Panama CityMilan

PTY - MXP

PTYMXP

Panama City Tocumen Intl

Mon 2/23

7:05 pm-9:20 pm

1 stop20h 15m

Milan Malpensa

Mon 3/9

7:55 am-4:45 pm

1 stop14h 50m

$714

Panama CityMilan

PTY - MXP

PTYMXP

Panama City Tocumen Intl

Mon 5/18

8:25 pm-5:15 pm

1 stop13h 50m

Milan Malpensa

Thu 5/21

11:05 am-6:40 pm

1 stop14h 35m

$763

Panama CityMilan

PTY - LIN

PTYLIN

Panama City Tocumen Intl

Mon 2/2

6:45 pm-10:55 pm

1 stop22h 10m

Milan Linate

Mon 2/16

12:20 pm-8:10 pm

1 stop13h 50m

$788

Panama CityMilan

PTY - LIN

PTYLIN

Panama City Tocumen Intl

Mon 2/16

10:05 pm-10:55 pm

1 stop18h 50m

Milan Linate

Thu 3/5

2:55 pm-8:10 pm

1 stop35h 15m

$801

Panama CityMilan

PTY - MXP

PTYMXP

Panama City Tocumen Intl

Wed 12/31

10:20 pm-11:00 pm

1 stop18h 40m

Milan Malpensa

Sat 1/31

6:25 pm-8:10 pm

1 stop31h 45m

$807

Panama CityMilan

PTY - LIN

PTYLIN

Panama City Tocumen Intl

Mon 2/23

10:20 pm-10:25 pm

1 stop18h 05m

Milan Linate

Mon 3/9

12:20 pm-8:10 pm

1 stop13h 50m

$816

Panama CityMilan

PTY - LIN

PTYLIN

Panama City Tocumen Intl

Thu 12/25

6:45 pm-10:55 pm

1 stop22h 10m

Milan Linate

Mon 1/26

6:30 am-7:55 pm

1 stop19h 25m

$851

Panama CityMilan

PTY - MXP

PTYMXP

Panama City Tocumen Intl

Tue 2/17

9:30 pm-5:20 pm

1 stop13h 50m

Milan Malpensa

Thu 2/26

10:50 am-7:45 pm

1 stop14h 55m

$865

Panama CityMilan

PTY - MXP

PTYMXP

Panama City Tocumen Intl

Thu 2/19

9:30 pm-5:20 pm

1 stop13h 50m

Milan Malpensa

Fri 2/27

10:50 am-7:45 pm

1 stop14h 55m

$865

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/4

Showing 1-10 of 29 results
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Compare providers for flights from Panama City to Milan

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Milan in December.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City-Milan flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Panama City-Milan flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Panama City-Milan flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Milan flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Milan flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Milan

Have a flexible travel schedule? Discover the best time to fly to Milan from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Milan

How far ahead should I book a flight from Panama City to Milan?

Use this chart to determine the optimal time to book a round-trip flight from Panama City to Milan. Price data was last updated on November 28, 2025.

The price you pay for your flight from Panama City to Milan may vary depending on when you book. For the best chance of a lower fare, look to book 33 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Panama City to Milan?

Currently, June is the cheapest month in which you can book a flight from Panama City to Milan (average of $383). Flying from Panama City to Milan in January is currently the most expensive (average of $836). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What’s the top layover airport for flights from Panama City to Milan?

Share of 1-stop round-trip flights from Panama City to Milan chosen by Cheapflights users in the past 12 months, using the same layover each way.

Frankfurt am Main (FRA) – chosen by Cheapflights users on 80% of 1-stop itineraries from Panama City to Milan on Cheapflights.

What’s the cheapest layover airport for flights from Panama City to Milan?

Average round-trip fare for 1-stop flights from Panama City to Milan, chosen by Cheapflights users in the past 12 months, with the same layover each way.

Frankfurt am Main (FRA) is the most affordable 1-stop option, with an average round-trip price of $921.

What’s the fastest layover option from Panama City to Milan?

Shortest average travel time for 1-stop one-way flights from Panama City to Milan, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.

Flights via Istanbul (IST) have the shortest average one-way travel time for 1-stop routes: 16h 55m.

Which airport typically offers the quickest layover for flights from Panama City to Milan?

Average layover duration for 1-stop one-way flights from Panama City to Milan, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.

Flights via Istanbul (IST) offer the fastest connection on this route, with an average layover time of 1h 33m.

Reviews of airlines servicing Milan

Get insights into the airlines that provide service to Milan. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Milan. Reviews last updated December 4, 2025.
Peruse reviews from past customers who have flown with Air France, Turkish Airlines, and Air Europa from Panama City to Milan to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Air France
7.4
Good
1,502 reviews

Comfort

7.3

Overall

7.4

Boarding

7.4

Crew

8.2

Food

7.0

Entertainment

7.0

Reviews

1 / 20
4.0
Okay

Hazel,Nov 2025

CDG - FCO

My experience with Air France was very disappointing. They claimed the flight was full and required me to check in my carry-on bag, yet once on board, there was plenty of overhead compartment space available. Several passengers with larger and heavier bags were allowed to bring theirs on without any issue. The inconsistency felt unfair and frustrating.
Air France
7.4
Good
1,502 reviews
Air France
7.4
Good
1,502 reviews

Comfort

7.3

Overall

7.4

Boarding

7.4

Crew

8.2

Food

7.0

Entertainment

7.0

Reviews

1 / 20
4.0
Okay

Hazel,Nov 2025

CDG - FCO

My experience with Air France was very disappointing. They claimed the flight was full and required me to check in my carry-on bag, yet once on board, there was plenty of overhead compartment space available. Several passengers with larger and heavier bags were allowed to bring theirs on without any issue. The inconsistency felt unfair and frustrating.
Turkish Airlines
7.3
Good
4,077 reviews
Air France
7.4
Good
1,502 reviews

Comfort

7.3

Overall

7.4

Boarding

7.4

Crew

8.2

Food

7.0

Entertainment

7.0

Reviews

1 / 20
4.0
Okay

Hazel,Nov 2025

CDG - FCO

My experience with Air France was very disappointing. They claimed the flight was full and required me to check in my carry-on bag, yet once on board, there was plenty of overhead compartment space available. Several passengers with larger and heavier bags were allowed to bring theirs on without any issue. The inconsistency felt unfair and frustrating.
Air Europa
7.0
Good
569 reviews
Air France
7.4
Good
1,502 reviews

Comfort

7.3

Overall

7.4

Boarding

7.4

Crew

8.2

Food

7.0

Entertainment

7.0

Reviews

1 / 20
4.0
Okay

Hazel,Nov 2025

CDG - FCO

My experience with Air France was very disappointing. They claimed the flight was full and required me to check in my carry-on bag, yet once on board, there was plenty of overhead compartment space available. Several passengers with larger and heavier bags were allowed to bring theirs on without any issue. The inconsistency felt unfair and frustrating.
Condor
6.4
Okay
389 reviews
Air France
7.4
Good
1,502 reviews

Comfort

7.3

Overall

7.4

Boarding

7.4

Crew

8.2

Food

7.0

Entertainment

7.0

Reviews

1 / 20
4.0
Okay

Hazel,Nov 2025

CDG - FCO

My experience with Air France was very disappointing. They claimed the flight was full and required me to check in my carry-on bag, yet once on board, there was plenty of overhead compartment space available. Several passengers with larger and heavier bags were allowed to bring theirs on without any issue. The inconsistency felt unfair and frustrating.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Milan. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Milan?

    Panama City Tocumen Intl (PTY) is the airport you will fly out of if you book a flight from Panama City to Milan. You should not have trouble finding flights to Milan from Tocumen Intl; the airport handles an average of 0 outbound flights to Milan per day. You should also have plenty of airline options to choose from since 2 airlines have flights from the Panama City airport to Milan. It is only a 11.4 mi journey to Tocumen Intl (PTY) from Panama City’s city center.

  • How long is the flight from Panama City to Milan?

    Airlines like KLM, Condor, and Air Europa fly from Panama City to Milan in about 13h 50m. The time it takes to get you to your destination can typically vary by up to 6h 25m. There are 5677 mi between Panama City and Milan. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Panama City to Milan round-trip?

    Cheapflights users have booked flights from Panama City to Milan round-trip from $678. Another airline that can offer you cheap pricing is Air France. These flights start at 21% lower than the current average price 3 months from now.

  • Can I find deals for flights from Panama City to Milan that include hotel bookings?

    Yes. In addition to deals on Panama City to Milan flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Milan?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Milan.

  • Can I find deals for business class flights from Panama City to Milan?

    Yes. Cheapflights offers flight deals from Panama City to Milan by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Milan?

    Currently, June is the cheapest month in which you can book a flight from Panama City to Milan (average of $383). Flying from Panama City to Milan in January is currently the most expensive (average of $836). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Milan?

Book flights to Milan if you plan to visit one of these locations
Monza
Menaggio
Rho
Lainate
Porlezza
Novara
Assago
Bellagio
Stresa
Domodossola

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Top 2 airlines flying from Panama City to Milan

Discover the top 2 airlines that operate flights from Panama City to Milan. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
Turkish AirlinesCheapest$678Average$969FlexibilityNo cancel feeOn-time77%
Air FranceCheapest$783Average$884FlexibilityNo cancel feeOn-time77%

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