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Italy

$540+ Cheap flights from Panama City (PTY) to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/8. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — NAP
Jul 6 — Jul 131
Sun 7/6
Sun 7/13
1 adult, Economy
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Cheap flight deals from Panama City to Italy

Keep the following information in mind while searching for Panama City to Italy flight deals. Data was last updated July 1, 2025.

Round-trip from

$684
(Gotogate)

One-way from

$540
(Air Europa)

Popular in

July

Cheapest in

March

Average price

$971
From Panama City Tocumen Intl to Italy
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One-way flight from Panama City Tocumen Intl to Italy
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Highest demand for flights based on searches. 7% potential increase in price ($69 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Panama City to Italy

Cheapest flights from Panama City to Italy
Explore the most affordable flight options available from Panama City to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 1, 2025.

This Gotogate deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/309:55 pmPTY - MXP
1 stop37h 15mTurkish Airlines
Fri 8/296:50 amMXP - PTY
1 stop20h 10mTurkish Airlines
Deal found 7/1$684
This Turkish Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/89:45 pmPTY - FCO
1 stop18h 10mTurkish Airlines
Sat 11/226:45 amFCO - PTY
1 stop19h 05mTurkish Airlines
Deal found 6/30$728
This KLM deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/277:55 pmPTY - LIN
1 stop16h 50mMultiple Airlines
Wed 8/271:00 pmLIN - PTY
1 stop34h 50mMultiple Airlines
Deal found 6/30$777
This Air France deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/197:55 pmPTY - LIN
1 stop19h 35mAir France
Sun 11/239:45 amLIN - PTY
1 stop16h 25mAir France
Deal found 6/30$778
This Gotogate deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2511:05 amPTY - MXP
1 stop13h 55mCondor
Sun 10/129:00 amMXP - PTY
1 stop24h 40mCondor
Deal found 6/30$789
This Air France deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/217:55 pmPTY - FCO
1 stop30h 00mAir France
Wed 10/13:50 pmFCO - PTY
1 stop32h 55mAir France
Deal found 7/1$802
This KLM deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/102:05 pmPTY - FCO
1 stop34h 30mMultiple Airlines
Sat 9/206:30 amFCO - PTY
1 stop17h 20mMultiple Airlines
Deal found 7/1$815
This KLM deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/66:50 pmPTY - FCO
1 stop14h 45mKLM
Sat 7/127:40 pmFCO - PTY
1 stop28h 10mKLM
Deal found 6/30$819
This Air Europa deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/258:25 pmPTY - MXP
1 stop13h 50mAir Europa
Sun 10/1911:05 amMXP - PTY
1 stop14h 35mAir Europa
Deal found 6/30$828
This FlightHub deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/248:25 pmPTY - FCO
1 stop14h 00mAir Europa
Wed 10/2910:30 amFCO - PTY
1 stop15h 15mAir Europa
Deal found 6/30$840
This FlightHub deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2511:05 amPTY - FCO
1 stop22h 50mCondor
Sun 9/78:20 amFCO - PTY
1 stop25h 20mCondor
Deal found 7/1$869
This Air France deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/227:55 pmPTY - MXP
1 stop31h 30mAir France
Sat 10/47:20 pmMXP - PTY
1 stop29h 25mAir France
Deal found 7/1$875

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 1, 2025.
Use the filters below to find and compare flights from Panama City to Italy that are best for you.

Fly from

Panama City

Fly to

Italy

Route

Depart

Return

Price

Panama CityMilan

PTY - MXP

PTYMXP

Panama City Tocumen Intl

Wed 7/30

9:55 pm-6:10 pm

1 stop37h 15m

Milan Malpensa

Fri 8/29

6:50 am-8:00 pm

1 stop20h 10m

$684

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Sat 11/8

9:45 pm-9:55 pm

1 stop18h 10m

Rome Fiumicino

Sat 11/22

6:45 am-7:50 pm

1 stop19h 05m

$728

Panama CityMilan

PTY - LIN

PTYLIN

Panama City Tocumen Intl

Sun 7/27

7:55 pm-7:45 pm

1 stop16h 50m

Milan Linate

Wed 8/27

1:00 pm-4:50 pm

1 stop34h 50m

$777

Panama CityMilan

PTY - LIN

PTYLIN

Panama City Tocumen Intl

Sun 10/19

7:55 pm-10:30 pm

1 stop19h 35m

Milan Linate

Sun 11/23

9:45 am-8:10 pm

1 stop16h 25m

$778

Panama CityMilan

PTY - MXP

PTYMXP

Panama City Tocumen Intl

Thu 9/25

11:05 am-8:00 am

1 stop13h 55m

Milan Malpensa

Sun 10/12

9:00 am-2:40 am

1 stop24h 40m

$789

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Sun 9/21

7:55 pm-8:55 am

1 stop30h 00m

Rome Fiumicino

Wed 10/1

3:50 pm-5:45 pm

1 stop32h 55m

$802

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Wed 9/10

2:05 pm-7:35 am

1 stop34h 30m

Rome Fiumicino

Sat 9/20

6:30 am-4:50 pm

1 stop17h 20m

$815

Panama CityMilan

PTY - MXP

PTYMXP

Panama City Tocumen Intl

Thu 9/25

8:25 pm-5:15 pm

1 stop13h 50m

Milan Malpensa

Sun 10/19

11:05 am-6:40 pm

1 stop14h 35m

$828

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Fri 10/24

8:25 pm-5:25 pm

1 stop14h 00m

Rome Fiumicino

Wed 10/29

10:30 am-7:45 pm

1 stop15h 15m

$840

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Mon 8/25

11:05 am-4:55 pm

1 stop22h 50m

Rome Fiumicino

Sun 9/7

8:20 am-2:40 am

1 stop25h 20m

$869

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Showing 1-10 of 42 results
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Best time to book a flight from Panama City to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Italy

What is the cheapest month to book a flight from Panama City to Italy?

Currently, January is the cheapest month in which you can book a flight from Panama City to Italy (average of $703). Flying from Panama City to Italy in June is currently the most expensive (average of $1,211). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to IT?

Find hourly flight availability from Panama City to Italy. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 1, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City to Italy as you normally would.

Reviews of airlines servicing Italy

Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated July 1, 2025.
Get a feel of what it's like to fly with KLM, Air France, and United Airlines from Panama City to Italy by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.8
Good
1,366 reviews

Comfort

7.7

Entertainment

7.1

Overall

7.8

Boarding

7.8

Crew

8.4

Food

7.2

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
KLM
7.8
Good
1,366 reviews
KLM
7.8
Good
1,366 reviews

Comfort

7.7

Entertainment

7.1

Overall

7.8

Boarding

7.8

Crew

8.4

Food

7.2

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
Air France
7.5
Good
1,472 reviews
KLM
7.8
Good
1,366 reviews

Comfort

7.7

Entertainment

7.1

Overall

7.8

Boarding

7.8

Crew

8.4

Food

7.2

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
United Airlines
7.4
Good
8,858 reviews
KLM
7.8
Good
1,366 reviews

Comfort

7.7

Entertainment

7.1

Overall

7.8

Boarding

7.8

Crew

8.4

Food

7.2

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
Turkish Airlines
7.3
Good
3,886 reviews
KLM
7.8
Good
1,366 reviews

Comfort

7.7

Entertainment

7.1

Overall

7.8

Boarding

7.8

Crew

8.4

Food

7.2

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
American Airlines
7.2
Good
10,000 reviews
KLM
7.8
Good
1,366 reviews

Comfort

7.7

Entertainment

7.1

Overall

7.8

Boarding

7.8

Crew

8.4

Food

7.2

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Italy?

    Most people fly from Panama City Tocumen Intl (PTY) if they book a flight from Panama City to Italy. Panama City Tocumen Intl is conveniently located just 11.4 mi from Panama City’s city center.

  • What are the cheapest airlines to fly from Panama City to Italy one-way?

    For one-way options, check prices for Air Europa. According to our data, you can fly for as low as $540. Users have also found prices from $541 and $569 on KLM and Turkish Airlines, respectively.

  • What are the most popular routes from Panama City to Italy?

    When deciding which route to take from Panama City to Italy consider Panama City Tocumen Intl - Rome Fiumicino, Panama City Tocumen Intl - Milan Linate or Panama City Tocumen Intl - Milan Malpensa as they are the most popular.

  • Can I find deals for flights from Panama City to Italy that include hotel bookings?

    Yes. In addition to deals on Panama City to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Italy.

  • Can I find deals for business class flights from Panama City to Italy?

    Yes. Cheapflights offers flight deals from Panama City to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Italy?

    Currently, January is the cheapest month in which you can book a flight from Panama City to Italy (average of $703). Flying from Panama City to Italy in June is currently the most expensive (average of $1,211). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama City to Italy

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Panama City to Italy

Discover the top 5 airlines that operate flights from Panama City to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
Turkish AirlinesCheapest$692Average$854FlexibilityNo cancel feeOn-time77%
IberiaCheapest$747Average$886FlexibilityNo cancel feeOn-time77%
Air EuropaCheapest$771Average$967FlexibilityNo cancel feeOn-time83%
Air FranceCheapest$783Average$920FlexibilityNo cancel feeOn-time77%
KLMCheapest$796Average$1,024FlexibilityNo cancel feeOn-time75%

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