$564+ Cheap flights from Panama City (PTY) to Italy
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/28. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — NAP
Jul 5 — Jul 121
Round-trip
1 adult, Economy
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Cheapest flights from Panama City to ItalyExplore the most affordable flight options available from Panama City to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 5, 2026.
Explore the most affordable flight options available from Panama City to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 5, 2026.
This Expedia deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/29:05 pm
PTY
- FCO
1 stop20h 10m
Iberia
Mon 8/2412:00 pm
FCO
- PTY
1 stop14h 35m
Iberia
Deal found 6/2![Iberia logo]()
$821
This Booking.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1410:20 pm
PTY
- MXP
1 stop32h 50m
Turkish Airlines
Thu 10/223:15 pm
MXP
- PTY
1 stop36h 10m
Turkish Airlines
Deal found 6/4![Turkish Airlines logo]()
$826
This KLM deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/309:55 pm
PTY
- MXP
1 stop18h 05m
Air France
Mon 8/316:45 am
MXP
- PTY
2 stops17h 05m
Air France
Deal found 6/4![Air France logo]()
$829
This KLM deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/309:55 pm
PTY
- LIN
1 stop17h 35m
Air France
Wed 9/28:45 pm
LIN
- PTY
2 stops27h 05m
Air France
Deal found 6/4![Air France logo]()
$831
This Orbitz deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:35 pm
PTY
- FCO
1 stop18h 55m
Iberia
Tue 11/172:45 pm
FCO
- PTY
1 stop32h 20m
Iberia
Deal found 6/4![Iberia logo]()
$832
This KLM deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/309:55 pm
PTY
- LIN
1 stop17h 35m
Air France
Mon 8/316:25 am
LIN
- PTY
2 stops17h 25m
Air France
Deal found 6/4![Air France logo]()
$833
This Turkish Airlines deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/910:20 pm
PTY
- MXP
1 stop27h 25m
Turkish Airlines
Fri 10/236:50 am
MXP
- PTY
1 stop20h 35m
Turkish Airlines
Deal found 5/31![Turkish Airlines logo]()
$834
This Gotogate deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/29:45 pm
PTY
- FCO
1 stop34h 05m
Turkish Airlines
Thu 11/127:45 pm
FCO
- PTY
1 stop30h 20m
Turkish Airlines
Deal found 5/31![Turkish Airlines logo]()
$840
This Booking.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/710:20 pm
PTY
- FCO
1 stop37h 05m
Turkish Airlines
Fri 10/237:05 am
FCO
- PTY
1 stop20h 20m
Turkish Airlines
Deal found 6/2![Turkish Airlines logo]()
$841
This Turkish Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/710:20 pm
PTY
- MXP
1 stop18h 25m
Turkish Airlines
Fri 10/236:50 am
MXP
- PTY
1 stop20h 35m
Turkish Airlines
Deal found 6/3![Turkish Airlines logo]()
$844
This KLM deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/29:55 pm
PTY
- FCO
2 stops17h 50m
Multiple Airlines
Mon 8/246:05 am
FCO
- PTY
1 stop20h 40m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$855
This Turkish Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:45 pm
PTY
- FCO
1 stop30h 05m
Turkish Airlines
Mon 11/236:40 am
FCO
- PTY
1 stop19h 25m
Turkish Airlines
Deal found 6/2![Turkish Airlines logo]()
$856
Best flights from Panama City to ItalyDiscover carefully curated flight deals from Panama City to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 5, 2026.
Discover carefully curated flight deals from Panama City to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 5, 2026.
This Turkish Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/29:45 pm
PTY
- FCO
1 stop18h 10m
Turkish Airlines
Thu 11/1211:15 am
FCO
- PTY
1 stop38h 50m
Turkish Airlines
Deal found 6/3![Turkish Airlines logo]()
$857
This KLM deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/289:55 pm
PTY
- FLR
2 stops17h 35m
KLM
Wed 10/78:35 pm
FLR
- PTY
2 stops27h 15m
KLM
Deal found 6/2![KLM logo]()
$914
This United Airlines deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/3010:55 pm
PTY
- FCO
2 stops26h 00m
United Airlines
Wed 9/912:55 pm
FCO
- PTY
1 stop37h 36m
United Airlines
Deal found 5/31![United Airlines logo]()
$918
This Air Europa deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/228:25 pm
PTY
- FCO
1 stop14h 00m
Air Europa
Wed 9/304:35 pm
FCO
- PTY
1 stop33h 05m
Air Europa
Deal found 5/31![Air Europa logo]()
$922
This Air France deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:55 pm
PTY
- TRN
1 stop28h 45m
Multiple Airlines
Sun 10/46:05 am
TRN
- PTY
2 stops20h 40m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$966
This Turkish Airlines deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:50 pm
PTY
- FCO
1 stop17h 30m
Turkish Airlines
Mon 11/236:40 am
FCO
- PTY
1 stop19h 25m
Turkish Airlines
Deal found 5/31![Turkish Airlines logo]()
$857
This United Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/3010:55 pm
PTY
- FCO
2 stops26h 00m
United Airlines
Fri 9/1112:55 pm
FCO
- PTY
1 stop37h 36m
United Airlines
Deal found 6/1![United Airlines logo]()
$918
This Turkish Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/309:45 pm
PTY
- NAP
1 stop28h 35m
Turkish Airlines
Sun 11/157:35 pm
NAP
- PTY
1 stop30h 30m
Turkish Airlines
Deal found 6/3![Turkish Airlines logo]()
$868
This Air Europa deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:25 pm
PTY
- VCE
1 stop14h 10m
Air Europa
Fri 10/2310:45 am
VCE
- PTY
1 stop14h 55m
Air Europa
Deal found 6/1![Air Europa logo]()
$956
This United Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/610:00 am
PTY
- FCO
1 stop15h 55m
United Airlines
Mon 11/1611:00 am
FCO
- PTY
2 stops39h 02m
United Airlines
Deal found 6/2![United Airlines logo]()
$919
This Turkish Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:10 pm
PTY
- TRN
1 stop30h 20m
Turkish Airlines
Sun 10/46:50 pm
TRN
- PTY
1 stop32h 35m
Turkish Airlines
Deal found 6/3![Turkish Airlines logo]()
$886
This KLM deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/189:55 pm
PTY
- TRN
2 stops17h 45m
KLM
Mon 9/216:05 am
TRN
- PTY
2 stops20h 40m
KLM
Deal found 6/4![KLM logo]()
$1,087
This KLM deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:55 pm
PTY
- LIN
2 stops17h 55m
Multiple Airlines
Wed 8/268:45 pm
LIN
- PTY
2 stops27h 05m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$1,103
This United Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:45 am
PTY
- FCO
2 stops20h 30m
United Airlines
Fri 10/233:20 pm
FCO
- PTY
2 stops35h 11m
United Airlines
Deal found 6/2![United Airlines logo]()
$919
This Turkish Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/319:45 pm
PTY
- MXP
1 stop38h 05m
Turkish Airlines
Wed 11/42:35 pm
MXP
- PTY
2 stops32h 35m
Turkish Airlines
Deal found 6/2![Turkish Airlines logo]()
$887
This United Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/153:30 pm
PTY
- FCO
2 stops33h 05m
United Airlines
Thu 7/3011:00 am
FCO
- PTY
1 stop24h 04m
United Airlines
Deal found 6/2![United Airlines logo]()
$919
This United deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/299:13 am
PTY
- LIN
2 stops22h 27m
Multiple Airlines
Wed 9/910:35 am
LIN
- PTY
2 stops27h 15m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$1,141
This Turkish Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1910:20 pm
PTY
- VCE
1 stop31h 45m
Turkish Airlines
Fri 10/239:20 am
VCE
- PTY
1 stop18h 05m
Turkish Airlines
Deal found 6/4![Turkish Airlines logo]()
$917
This United Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2010:55 pm
PTY
- FCO
2 stops27h 20m
United Airlines
Fri 7/3111:00 am
FCO
- PTY
1 stop24h 04m
United Airlines
Deal found 6/2![United Airlines logo]()
$927
This KLM deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:50 pm
PTY
- LIN
2 stops20h 40m
Multiple Airlines
Fri 10/236:40 am
LIN
- PTY
1 stop17h 10m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$1,143
This United Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/167:55 am
PTY
- NAP
2 stops20h 45m
United Airlines
Thu 7/232:00 pm
NAP
- PTY
2 stops33h 12m
United Airlines
Deal found 6/1![United Airlines logo]()
$928
This Turkish Airlines deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/188:05 pm
PTY
- NAP
1 stop16h 40m
Turkish Airlines
Sun 11/87:35 pm
NAP
- PTY
1 stop30h 30m
Turkish Airlines
Deal found 5/31![Turkish Airlines logo]()
$942
This United Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/1310:00 am
PTY
- MXP
2 stops38h 30m
United Airlines
Wed 9/233:20 pm
MXP
- PTY
2 stops35h 11m
United Airlines
Deal found 6/3![United Airlines logo]()
$930
This United Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/110:55 pm
PTY
- VCE
2 stops50h 00m
United Airlines
Wed 7/1511:05 am
VCE
- PTY
1 stop23h 59m
United Airlines
Deal found 6/1![United Airlines logo]()
$931
This Turkish Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:50 pm
PTY
- NAP
1 stop31h 30m
Turkish Airlines
Sun 11/227:35 pm
NAP
- PTY
1 stop30h 30m
Turkish Airlines
Deal found 6/1![Turkish Airlines logo]()
$1,035
This KLM deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/39:55 pm
PTY
- TRN
2 stops17h 45m
Multiple Airlines
Sun 8/26:00 am
TRN
- PTY
1 stop20h 45m
Multiple Airlines
Deal found 5/31![Multiple Airlines logo]()
$1,384
This Air Europa deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/48:25 pm
PTY
- TRS
2 stops35h 05m
Air Europa
Tue 9/2211:15 am
TRS
- PTY
2 stops38h 25m
Air Europa
Deal found 6/1![Air Europa logo]()
$1,699
This United Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/710:00 am
PTY
- VCE
2 stops40h 05m
United Airlines
Thu 7/2311:05 am
VCE
- PTY
1 stop23h 59m
United Airlines
Deal found 6/3![United Airlines logo]()
$931
This Turkish Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/410:20 pm
PTY
- BLQ
1 stop28h 10m
Turkish Airlines
Sun 9/202:55 pm
BLQ
- PTY
1 stop36h 30m
Turkish Airlines
Deal found 6/5![Turkish Airlines logo]()
$1,072
This United Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/14:41 pm
PTY
- FCO
2 stops36h 14m
United Airlines
Wed 11/111:15 pm
FCO
- PTY
2 stops36h 47m
United Airlines
Deal found 6/2![United Airlines logo]()
$931
Last-minute flights from Panama City to ItalyDiscover last-minute flight deals from Panama City to Italy. Data last updated June 5, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Italy. Data last updated June 5, 2026 and is based on user searches.
This KLM deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/309:55 pm
PTY
- MXP
1 stop18h 05m
Air France
Mon 8/316:45 am
MXP
- PTY
2 stops17h 05m
Air France
Deal found 6/4![Air France logo]()
$829
This KLM deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/309:55 pm
PTY
- LIN
1 stop17h 35m
Air France
Wed 9/28:45 pm
LIN
- PTY
2 stops27h 05m
Air France
Deal found 6/4![Air France logo]()
$831
This KLM deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/309:55 pm
PTY
- LIN
1 stop17h 35m
Air France
Mon 8/316:25 am
LIN
- PTY
2 stops17h 25m
Air France
Deal found 6/4![Air France logo]()
$833
This KLM deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/309:55 pm
PTY
- LIN
2 stops16h 25m
Multiple Airlines
Wed 9/28:45 pm
LIN
- PTY
2 stops27h 05m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$863
This KLM deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/309:55 pm
PTY
- LIN
2 stops16h 25m
Multiple Airlines
Mon 8/316:25 am
LIN
- PTY
2 stops17h 25m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$865
This United Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/510:55 pm
PTY
- FCO
1 stop25h 40m
United Airlines
Mon 7/2012:55 pm
FCO
- PTY
1 stop22h 09m
United Airlines
Deal found 6/2![United Airlines logo]()
$917
This United Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/119:45 am
PTY
- FCO
1 stop18h 10m
United Airlines
Sat 7/1812:55 pm
FCO
- PTY
1 stop22h 09m
United Airlines
Deal found 6/2![United Airlines logo]()
$919
This KLM deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/129:55 pm
PTY
- VCE
2 stops17h 25m
Multiple Airlines
Mon 8/315:55 am
VCE
- PTY
2 stops17h 55m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$919
This United Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/139:45 am
PTY
- FCO
1 stop18h 10m
United Airlines
Fri 7/2411:00 am
FCO
- PTY
1 stop24h 04m
United Airlines
Deal found 6/2![United Airlines logo]()
$923
This United Airlines deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/153:30 pm
PTY
- FCO
2 stops33h 45m
United Airlines
Thu 7/3010:20 am
FCO
- PTY
2 stops24h 44m
United Airlines
Deal found 5/31![United Airlines logo]()
$918
This United Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/169:45 am
PTY
- NAP
1 stop18h 55m
United Airlines
Thu 7/232:00 pm
NAP
- PTY
2 stops35h 37m
United Airlines
Deal found 6/1![United Airlines logo]()
$928
This United Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2010:55 pm
PTY
- FCO
2 stops27h 20m
United Airlines
Fri 7/3111:00 am
FCO
- PTY
1 stop24h 04m
United Airlines
Deal found 6/2![United Airlines logo]()
$927
One-way flights from Panama City to ItalySearch for one-way flight options from Panama City to Italy. Find affordable one-way fares based on user searches. Data last updated June 5, 2026.
Search for one-way flight options from Panama City to Italy. Find affordable one-way fares based on user searches. Data last updated June 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/2810:10 am
PTY
- VCE
3 stops54h 40m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$564
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/54:25 am
PTY
- FCO
3 stops38h 00m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$565
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/288:25 pm
PTY
- VCE
1 stop14h 10m
Air Europa
Deal found 6/1![Air Europa logo]()
$679
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/58:25 pm
PTY
- FCO
1 stop14h 00m
Air Europa
Deal found 6/1![Air Europa logo]()
$680
This Kiwi.com deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/178:25 pm
PTY
- MXP
1 stop13h 50m
Air Europa
Deal found 5/31![Air Europa logo]()
$681
This British Airways deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/109:30 pm
PTY
- FCO
1 stop19h 45m
Iberia
Deal found 6/4![Iberia logo]()
$681
This British Airways deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/309:05 pm
PTY
- MXP
1 stop14h 10m
Iberia
Deal found 6/1![Iberia logo]()
$689
This British Airways deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/59:05 pm
PTY
- FCO
1 stop20h 10m
Iberia
Deal found 6/1![Iberia logo]()
$689
This Air Europa deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:25 pm
PTY
- MXP
1 stop13h 50m
Air Europa
Deal found 6/3![Air Europa logo]()
$698
This Turkish Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/410:20 pm
PTY
- VCE
1 stop37h 40m
Turkish Airlines
Deal found 6/4![Turkish Airlines logo]()
$703
This Turkish Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/2410:20 pm
PTY
- BLQ
1 stop37h 00m
Turkish Airlines
Deal found 6/3![Turkish Airlines logo]()
$703
This Turkish Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3010:20 pm
PTY
- MXP
1 stop18h 25m
Turkish Airlines
Deal found 6/1![Turkish Airlines logo]()
$703
Find flight deals from Panama City to Italy
Keep the following information in mind while searching for Panama City to Italy flight deals. Data was last updated June 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $821 (Expedia) |
One-way from | $564 (Kiwi.com) |
Popular in | January |
Cheapest in | April |
Average price | $953 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 5, 2026.
Use the filters below to find and compare flights from Panama City to Italy that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityRome
PTY - FCO
PTYFCO
Panama City Tocumen Intl
Mon 11/2
9:45 pm-9:55 pm
1 stop18h 10m
Rome Fiumicino
Thu 11/12
11:15 am-8:05 pm
1 stop38h 50m
$857
Panama CityRome
PTY - FCO
PTYFCO
Panama City Tocumen Intl
Mon 11/9
6:50 pm-6:20 pm
1 stop17h 30m
Rome Fiumicino
Mon 11/23
6:40 am-8:05 pm
1 stop19h 25m
$857
Panama CityNaples
PTY - NAP
PTYNAP
Panama City Tocumen Intl
Fri 10/30
9:45 pm-8:20 am
1 stop28h 35m
Naples
Sun 11/15
7:35 pm-8:05 pm
1 stop30h 30m
$868
Panama CityTurin
PTY - TRN
PTYTRN
Panama City Tocumen Intl
Thu 10/1
8:10 pm-9:30 am
1 stop30h 20m
Turin Citta Di Torino
Sun 10/4
6:50 pm-8:25 pm
1 stop32h 35m
$886
Panama CityMilan
PTY - MXP
PTYMXP
Panama City Tocumen Intl
Sat 10/31
9:45 pm-5:50 pm
1 stop38h 05m
Milan Malpensa
Wed 11/4
2:35 pm-5:10 pm
2 stops32h 35m
$887
Panama CityFlorence
PTY - FLR
PTYFLR
Panama City Tocumen Intl
Mon 9/28
9:55 pm-10:30 pm
2 stops17h 35m
Florence Peretola
Wed 10/7
8:35 pm-4:50 pm
2 stops27h 15m
$914
Panama CityVenice
PTY - VCE
PTYVCE
Panama City Tocumen Intl
Mon 10/19
10:20 pm-1:05 pm
1 stop31h 45m
Venice Marco Polo
Fri 10/23
9:20 am-8:25 pm
1 stop18h 05m
$917
Panama CityRome
PTY - FCO
PTYFCO
Panama City Tocumen Intl
Sun 8/30
10:55 pm-7:55 am
2 stops26h 00m
Rome Fiumicino
Wed 9/9
12:55 pm-7:31 pm
1 stop37h 36m
$918
Panama CityRome
PTY - FCO
PTYFCO
Panama City Tocumen Intl
Sun 8/30
10:55 pm-7:55 am
2 stops26h 00m
Rome Fiumicino
Fri 9/11
12:55 pm-7:31 pm
1 stop37h 36m
$918
Panama CityRome
PTY - FCO
PTYFCO
Panama City Tocumen Intl
Fri 11/6
10:00 am-7:55 am
1 stop15h 55m
Rome Fiumicino
Mon 11/16
11:00 am-8:02 pm
2 stops39h 02m
$919
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Panama City to Italy
Have a flexible travel schedule? Discover the best time to fly to Italy from Panama City with our price prediction graph.
PTY-VCE
PTY-FCO
PTY-MXP
PTY-BLQ
PTY-LIN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Italy
PTY-IT0
PTY-VCE
PTY-FCO
PTY-MXP
PTY-BLQ
What is the cheapest month to book a flight from Panama City to Italy?
Currently, September is the cheapest month in which you can book a flight from Panama City to Italy (average of $312). Flying from Panama City to Italy in January is currently the most expensive (average of $743). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from Panama City to Italy?
The best time to book flights from Panama City to Italy is 88 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Reviews of airlines servicing Italy
Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated June 5, 2026.
Get a feel of what it's like to fly with KLM,Air France, andTurkish Airlines from Panama City to Italy by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.7
Crew
8.4
Food
7.3
Boarding
7.8
Entertainment
7.2
Overall
7.8
Reviews
1 / 20
6.0
GoodAnonymous,Apr 2026
OKC - ATL
Comfort
7.7
Crew
8.4
Food
7.3
Boarding
7.8
Entertainment
7.2
Overall
7.8
Reviews
1 / 20
6.0
GoodAnonymous,Apr 2026
OKC - ATL
Comfort
7.7
Crew
8.4
Food
7.3
Boarding
7.8
Entertainment
7.2
Overall
7.8
Reviews
1 / 20
6.0
GoodAnonymous,Apr 2026
OKC - ATL
Comfort
7.7
Crew
8.4
Food
7.3
Boarding
7.8
Entertainment
7.2
Overall
7.8
Reviews
1 / 20
6.0
GoodAnonymous,Apr 2026
OKC - ATL
Comfort
7.7
Crew
8.4
Food
7.3
Boarding
7.8
Entertainment
7.2
Overall
7.8
Reviews
1 / 20
6.0
GoodAnonymous,Apr 2026
OKC - ATL
Comfort
7.7
Crew
8.4
Food
7.3
Boarding
7.8
Entertainment
7.2
Overall
7.8
Reviews
1 / 20
6.0
GoodAnonymous,Apr 2026
OKC - ATL
Related info for your journey
Find useful and relevant information for your journey from Panama City to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Panama City to Italy
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Italy by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Panama City to Italy by cabin class
Find flights from Panama City to Italy, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Panama City and Italy flights
Browse other Panama City and Italy flight options. Last updated on June 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to Italy regions
Consider these flights traveling to Italy regions.
Top 3 airlines flying from Panama City to Italy
Discover the top 3 airlines that operate flights from Panama City to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$679 | Average$1,113 | FlexibilityNo cancel fee | On-time83% | |
| Cheapest$690 | Average$854 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$883 | Average$972 | FlexibilityNo cancel fee | On-time77% |