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$515+ Cheap flights from Panama City (PTY) to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/16. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — NAP
May 20 — May 271
Tue 5/20
Tue 5/27
1 adult, Economy
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Cheap flight deals from Panama City to Italy

Keep the following information in mind while searching for Panama City to Italy flight deals. Data was last updated May 15, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
2 stars

Round-trip from

$712
(Turkish Airlines)

One-way from

$515
(Kiwi.com)

Popular in

August

Cheapest in

March

Average price

$798
Provider with most accurate pricing for Panama City Tocumen Intl-Rome (ROM) flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Rome (ROM) flights.
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From Panama City Tocumen Intl to Italy
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One-way flight from Panama City Tocumen Intl to Italy
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Highest demand for flights based on searches. 9% potential increase in price ($87 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in May 2025
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Find flight deals from Panama City to Italy

Cheapest flights from Panama City to Italy
Explore the most affordable flight options available from Panama City to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 15, 2025.

This Turkish Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/199:55 pmPTY - MXP
1 stop27h 50mTurkish Airlines
Sat 9/278:10 pmMXP - PTY
1 stop30h 50mTurkish Airlines
Deal found 5/13$687
This Turkish Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/289:55 pmPTY - FCO
1 stop18h 35mTurkish Airlines
Thu 6/510:50 amFCO - PTY
1 stop40h 10mTurkish Airlines
Deal found 5/14$724
This Turkish Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/78:00 pmPTY - VCE
1 stop34h 05mTurkish Airlines
Sat 10/112:05 pmVCE - PTY
1 stop36h 55mTurkish Airlines
Deal found 5/14$735
This Air France deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/67:55 pmPTY - VCE
1 stop17h 45mAir France
Sun 9/149:25 amVCE - PTY
1 stop15h 20mAir France
Deal found 5/14$771
This KLM deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/186:50 pmPTY - LIN
1 stop21h 00mKLM
Sat 9/274:50 pmLIN - PTY
1 stop31h 00mKLM
Deal found 5/14$772
This KLM deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/277:55 pmPTY - LIN
1 stop16h 50mMultiple Airlines
Wed 8/2711:00 amLIN - PTY
1 stop36h 50mMultiple Airlines
Deal found 5/15$773
This Iberia deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/165:35 pmPTY - FCO
1 stop23h 40mIberia
Sun 5/258:25 pmFCO - PTY
1 stop26h 40mIberia
Deal found 5/15$783
This KLM deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/217:55 pmPTY - TRN
1 stop20h 30mMultiple Airlines
Sun 9/286:35 amTRN - PTY
2 stops17h 15mMultiple Airlines
Deal found 5/14$787
This Air France deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/207:55 pmPTY - FCO
1 stop14h 35mAir France
Mon 10/66:05 amFCO - PTY
1 stop18h 40mAir France
Deal found 5/15$788
This Turkish Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/49:55 pmPTY - TRN
1 stop37h 20mTurkish Airlines
Tue 6/1710:15 amTRN - PTY
1 stop40h 45mTurkish Airlines
Deal found 5/14$788
This Air France deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/97:55 pmPTY - FCO
1 stop30h 00mMultiple Airlines
Thu 9/256:30 amFCO - PTY
1 stop17h 20mMultiple Airlines
Deal found 5/15$796
This Condor deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Condor is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/159:37 amPTY - MXP
2 stops23h 38mMultiple Airlines
Sun 6/225:35 pmMXP - PTY
1 stop16h 05mMultiple Airlines
Deal found 5/15$800

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 15, 2025.
Use the filters below to find and compare flights from Panama City to Italy that are best for you.

Fly from

Panama City

Fly to

Italy

Route

Depart

Return

Price

Panama CityMilan

PTY - MXP

PTYMXP

Panama City Tocumen Intl

Fri 9/19

9:55 pm-8:45 am

1 stop27h 50m

Milan Malpensa

Sat 9/27

8:10 pm-8:00 pm

1 stop30h 50m

$687

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Wed 5/28

9:55 pm-11:30 pm

1 stop18h 35m

Rome Fiumicino

Thu 6/5

10:50 am-8:00 pm

1 stop40h 10m

$724

Panama CityVenice

PTY - VCE

PTYVCE

Panama City Tocumen Intl

Tue 10/7

8:00 pm-1:05 pm

1 stop34h 05m

Venice Marco Polo

Sat 10/11

2:05 pm-8:00 pm

1 stop36h 55m

$735

Panama CityVenice

PTY - VCE

PTYVCE

Panama City Tocumen Intl

Sat 9/6

7:55 pm-8:40 pm

1 stop17h 45m

Venice Marco Polo

Sun 9/14

9:25 am-5:45 pm

1 stop15h 20m

$771

Panama CityMilan

PTY - LIN

PTYLIN

Panama City Tocumen Intl

Thu 9/18

6:50 pm-10:50 pm

1 stop21h 00m

Milan Linate

Sat 9/27

4:50 pm-4:50 pm

1 stop31h 00m

$772

Panama CityMilan

PTY - LIN

PTYLIN

Panama City Tocumen Intl

Sun 7/27

7:55 pm-7:45 pm

1 stop16h 50m

Milan Linate

Wed 8/27

11:00 am-4:50 pm

1 stop36h 50m

$773

Panama CityTurin

PTY - TRN

PTYTRN

Panama City Tocumen Intl

Sun 9/21

7:55 pm-11:25 pm

1 stop20h 30m

Turin Citta Di Torino

Sun 9/28

6:35 am-4:50 pm

2 stops17h 15m

$787

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Sat 9/20

7:55 pm-5:30 pm

1 stop14h 35m

Rome Fiumicino

Mon 10/6

6:05 am-5:45 pm

1 stop18h 40m

$788

Panama CityTurin

PTY - TRN

PTYTRN

Panama City Tocumen Intl

Wed 6/4

9:55 pm-6:15 pm

1 stop37h 20m

Turin Citta Di Torino

Tue 6/17

10:15 am-8:00 pm

1 stop40h 45m

$788

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Tue 9/9

7:55 pm-8:55 am

1 stop30h 00m

Rome Fiumicino

Thu 9/25

6:30 am-4:50 pm

1 stop17h 20m

$796

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/14

Showing 1-10 of 41 results
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Best time to book a flight from Panama City to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Italy

What is the cheapest month to book a flight from Panama City to Italy?

Currently, January is the cheapest month in which you can book a flight from Panama City to Italy (average of $703). Flying from Panama City to Italy in June is currently the most expensive (average of $1,240). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to IT?

Find hourly flight availability from Panama City to Italy. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 15, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City to Italy as you normally would.

Rainfall in Italy by month

Plan your trip to Italy by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Italy ranges from 0.6 - 4.4 inches per month. November is typically the wettest month, when rainfall can reach 4.4 in. June is typically the driest time to visit Italy when rainfall is around 0.6 in.

Temperature in Italy by month

Plan your trip to Italy by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Italy, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Italy

Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated May 15, 2025.
Read through reviews of airlines operating flights from Panama City to Italy, such as Emirates, Delta and KLM. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Emirates
8.0
Very good
3,230 reviews

Food

7.8

Comfort

8.0

Entertainment

8.2

Overall

8.0

Boarding

8.1

Crew

8.3

Reviews

1 / 20
8.0
Excellent

Hoss,Mar 2025

TPE - DXB

One of Emirate claim to fame use to be excellent crew. But I think that has faded just a bit. While the first leg of my journey was impeccable, the second was good but not amazing. A few of the crew could have use a bit of smiley face, plus the sandwich served after take off was not good at all. I would have not served it at all.
Emirates
8.0
Very good
3,230 reviews
Emirates
8.0
Very good
3,230 reviews

Food

7.8

Comfort

8.0

Entertainment

8.2

Overall

8.0

Boarding

8.1

Crew

8.3

Reviews

1 / 20
8.0
Excellent

Hoss,Mar 2025

TPE - DXB

One of Emirate claim to fame use to be excellent crew. But I think that has faded just a bit. While the first leg of my journey was impeccable, the second was good but not amazing. A few of the crew could have use a bit of smiley face, plus the sandwich served after take off was not good at all. I would have not served it at all.
Delta
8.0
Very good
7,946 reviews
Emirates
8.0
Very good
3,230 reviews

Food

7.8

Comfort

8.0

Entertainment

8.2

Overall

8.0

Boarding

8.1

Crew

8.3

Reviews

1 / 20
8.0
Excellent

Hoss,Mar 2025

TPE - DXB

One of Emirate claim to fame use to be excellent crew. But I think that has faded just a bit. While the first leg of my journey was impeccable, the second was good but not amazing. A few of the crew could have use a bit of smiley face, plus the sandwich served after take off was not good at all. I would have not served it at all.
KLM
7.8
Good
1,344 reviews
Emirates
8.0
Very good
3,230 reviews

Food

7.8

Comfort

8.0

Entertainment

8.2

Overall

8.0

Boarding

8.1

Crew

8.3

Reviews

1 / 20
8.0
Excellent

Hoss,Mar 2025

TPE - DXB

One of Emirate claim to fame use to be excellent crew. But I think that has faded just a bit. While the first leg of my journey was impeccable, the second was good but not amazing. A few of the crew could have use a bit of smiley face, plus the sandwich served after take off was not good at all. I would have not served it at all.
Air France
7.4
Good
1,451 reviews
Emirates
8.0
Very good
3,230 reviews

Food

7.8

Comfort

8.0

Entertainment

8.2

Overall

8.0

Boarding

8.1

Crew

8.3

Reviews

1 / 20
8.0
Excellent

Hoss,Mar 2025

TPE - DXB

One of Emirate claim to fame use to be excellent crew. But I think that has faded just a bit. While the first leg of my journey was impeccable, the second was good but not amazing. A few of the crew could have use a bit of smiley face, plus the sandwich served after take off was not good at all. I would have not served it at all.
United Airlines
7.4
Good
8,731 reviews
Emirates
8.0
Very good
3,230 reviews

Food

7.8

Comfort

8.0

Entertainment

8.2

Overall

8.0

Boarding

8.1

Crew

8.3

Reviews

1 / 20
8.0
Excellent

Hoss,Mar 2025

TPE - DXB

One of Emirate claim to fame use to be excellent crew. But I think that has faded just a bit. While the first leg of my journey was impeccable, the second was good but not amazing. A few of the crew could have use a bit of smiley face, plus the sandwich served after take off was not good at all. I would have not served it at all.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Italy?

    Most people fly from Panama City Tocumen Intl (PTY) if they book a flight from Panama City to Italy. Panama City Tocumen Intl is conveniently located just 11.4 mi from Panama City’s city center.

  • What are the cheapest airlines to fly from Panama City to Italy one-way?

    For one-way options, check prices for Air Europa. According to our data, you can fly for as low as $525. Users have also found prices from $545 and $806 on Turkish Airlines and KLM, respectively.

  • What are the most popular routes from Panama City to Italy?

    When deciding which route to take from Panama City to Italy consider Panama City Tocumen Intl - Rome Fiumicino, Panama City Tocumen Intl - Milan Malpensa or Panama City Tocumen Intl - Trieste Ronchi dei Legionari as they are the most popular.

  • Can I find deals for flights from Panama City to Italy that include hotel bookings?

    Yes. In addition to deals on Panama City to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Italy.

  • Can I find deals for business class flights from Panama City to Italy?

    Yes. Cheapflights offers flight deals from Panama City to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Italy?

    Currently, January is the cheapest month in which you can book a flight from Panama City to Italy (average of $703). Flying from Panama City to Italy in June is currently the most expensive (average of $1,240). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Panama City to Italy

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Panama City to Italy

Discover the top 5 airlines that operate flights from Panama City to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
Air FranceCheapest$709Average$937FlexibilityNo cancel feeOn-time77%
IberiaCheapest$747Average$881FlexibilityNo cancel feeOn-time77%
United AirlinesCheapest$763Average$880FlexibilityNo cancel feeOn-time69%
Air EuropaCheapest$771Average$864FlexibilityNo cancel feeOn-time83%
KLMCheapest$1,546Average$1,878FlexibilityNo cancel feeOn-time75%

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