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$402+ Cheap flights from Columbia, MO (COU) to Mexico

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/29. Fares are subject to change and may not be available on all flights or dates of travel.
COU — MEX
Oct 14 — Oct 211
Tue 10/14
Tue 10/21
1 adult, Economy
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Cheap flight deals from Columbia to Mexico

Keep the following information in mind while searching for Columbia to Mexico flight deals. Data was last updated September 14, 2025.

Round-trip from

$402
(American Airlines)
From Columbia Regional to Mexico
Search Deals

Find flight deals from Columbia to Mexico

Cheapest flights from Columbia to Mexico
Explore the most affordable flight options available from Columbia to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2025.

This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/296:01 amCOU - CUN
1 stop6h 18mAmerican Airlines
Wed 11/54:23 pmCUN - COU
1 stop7h 16mAmerican Airlines
Deal found 9/13$402
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/137:46 pmCOU - PVR
1 stop15h 47mAmerican Airlines
Mon 11/172:40 pmPVR - COU
1 stop24h 28mAmerican Airlines
Deal found 9/13$493
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/36:17 pmCOU - CUN
1 stop20h 06mAmerican Airlines
Thu 11/65:08 pmCUN - COU
1 stop6h 26mAmerican Airlines
Deal found 9/11$506
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/136:33 pmCOU - CUN
1 stop16h 24mAmerican Airlines
Sat 9/207:50 amCUN - COU
1 stop8h 03mAmerican Airlines
Deal found 9/12$537
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/225:25 pmCOU - PVR
2 stops21h 48mAmerican Airlines
Sat 10/253:13 pmPVR - COU
2 stops18h 54mAmerican Airlines
Deal found 9/12$590
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/33:02 pmCOU - CUN
2 stops20h 52mUnited Airlines
Thu 11/68:39 amCUN - COU
2 stops13h 40mUnited Airlines
Deal found 9/11$635

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbia to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 14, 2025.
Use the filters below to find and compare flights from Columbia to Mexico that are best for you.

Fly from

Columbia

Fly to

Mexico

Route

Depart

Return

Price

ColumbiaCancún

COU - CUN

COUCUN

Columbia Regional

Wed 10/29

6:01 am-12:19 pm

1 stop6h 18m

Cancun

Wed 11/5

4:23 pm-10:39 pm

1 stop7h 16m

$402

ColumbiaPuerto Vallarta

COU - PVR

COUPVR

Columbia Regional

Thu 11/13

7:46 pm-11:33 am

1 stop15h 47m

Puerto Vallarta Ordaz

Mon 11/17

2:40 pm-3:08 pm

1 stop24h 28m

$493

ColumbiaCancún

COU - CUN

COUCUN

Columbia Regional

Mon 11/3

6:17 pm-3:23 pm

1 stop20h 06m

Cancun

Thu 11/6

5:08 pm-10:34 pm

1 stop6h 26m

$506

ColumbiaSan José del Cabo

COU - SJD

COUSJD

Columbia Regional

Fri 1/30

6:21 pm-11:55 am

1 stop18h 34m

San José del Cabo Los Cabos

Mon 2/2

11:50 am-9:09 pm

1 stop8h 19m

$518

ColumbiaPuerto Vallarta

COU - PVR

COUPVR

Columbia Regional

Wed 10/22

5:25 pm-2:13 pm

2 stops21h 48m

Puerto Vallarta Ordaz

Sat 10/25

3:48 pm-10:40 pm

1 stop5h 52m

$590

ColumbiaCancún

COU - CUN

COUCUN

Columbia Regional

Mon 11/3

3:02 pm-12:54 pm

2 stops20h 52m

Cancun

Thu 11/6

8:39 am-9:19 pm

2 stops13h 40m

$635

ColumbiaCancún

COU - CUN

COUCUN

Columbia Regional

Wed 2/18

7:21 am-6:05 pm

1 stop9h 44m

Cancun

Sun 2/22

8:59 am-4:23 pm

1 stop8h 24m

$1,324

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Best time to book a flight from Columbia to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from Columbia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbia to Mexico

What is the cheapest month to book a flight from Columbia, Missouri to Mexico?

Currently, May is the cheapest month in which you can book a flight from Columbia, Missouri to Mexico (average of $387). Flying from Columbia, Missouri to Mexico in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from COU to MX?

Find hourly flight availability from Columbia to Mexico. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 14, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Columbia, Missouri to Mexico as you normally would.

Reviews of airlines servicing Mexico

Get insights into the airlines that provide service to Mexico. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico. Reviews last updated September 14, 2025.
Peruse reviews from past customers who have flown with American Airlines from Columbia to Mexico to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Overall

7.2

Crew

8.0

Comfort

7.2

Boarding

7.5

Entertainment

6.9

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Overall

7.2

Crew

8.0

Comfort

7.2

Boarding

7.5

Entertainment

6.9

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Columbia to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Columbia to Mexico?

    Located just 11.1 mi from the city center, Columbia Regional (COU) is the airport most travelers will use when flying to Mexico from Columbia.

  • How long is the flight from Columbia, Missouri to Mexico?

    American Airlines can get you from Columbia, Missouri to Mexico in just under 6h 18m. Your travel time can differ by up to . Airlines will cover a distance of 1268 mi.

  • What are the most popular routes from Columbia, Missouri to Mexico?

    While some choose either Columbia Regional - Cancun or Columbia Regional - San José del Cabo Los Cabos, Columbia Regional - Puerto Vallarta Ordaz is the most popular route from Columbia, Missouri to Mexico.

  • Can I find deals for flights from Columbia to Mexico that include hotel bookings?

    Yes. In addition to deals on Columbia to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbia to Mexico?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbia to Mexico.

  • Can I find deals for business class flights from Columbia to Mexico?

    Yes. Cheapflights offers flight deals from Columbia to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbia, Missouri to Mexico?

    Currently, May is the cheapest month in which you can book a flight from Columbia, Missouri to Mexico (average of $387). Flying from Columbia, Missouri to Mexico in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from Columbia to Mexico

Discover the top airline that operate flights from Columbia to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$385Average$794FlexibilityNo cancel feeOn-time71%

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