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$407+ Cheap flights from Columbia, MO (COU) to Mexico

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/21. Fares are subject to change and may not be available on all flights or dates of travel.
COU — MEX
Feb 26 — Mar 51
Thu 2/26
Thu 3/5
1 adult, Economy
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Cheap flight deals from Columbia to Mexico

Cheapest flights from Columbia to Mexico
Explore the most affordable flight options available from Columbia to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.

This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/215:41 pm
COU
-
CUN
2 stops15h 46m
American Airlines
Tue 2/2411:30 am
CUN
-
COU
2 stops12h 10m
American Airlines
Deal found 1/26$407
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/267:43 pm
COU
-
CUN
1 stop16h 14m
American Airlines
Wed 4/2911:00 am
CUN
-
COU
1 stop8h 13m
American Airlines
Deal found 1/26$442
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:28 pm
COU
-
CUN
1 stop19h 20m
American Airlines
Wed 5/277:30 am
CUN
-
COU
1 stop11h 31m
American Airlines
Deal found 1/27$465
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/197:39 pm
COU
-
CUN
1 stop21h 18m
American Airlines
Wed 3/257:45 am
CUN
-
COU
1 stop11h 24m
American Airlines
Deal found 1/27$513
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:28 pm
COU
-
CUN
1 stop19h 20m
American Airlines
Tue 5/267:30 am
CUN
-
COU
1 stop9h 17m
American Airlines
Deal found 1/27$515
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/217:39 pm
COU
-
CUN
1 stop21h 18m
American Airlines
Wed 3/2510:30 am
CUN
-
COU
2 stops8h 39m
American Airlines
Deal found 1/25$545
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/197:31 pm
COU
-
PVR
2 stops17h 38m
American Airlines
Fri 7/314:05 pm
PVR
-
COU
2 stops17h 05m
American Airlines
Deal found 1/25$549
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/196:35 pm
COU
-
PVR
1 stop21h 12m
American Airlines
Fri 2/274:35 pm
PVR
-
COU
1 stop6h 01m
American Airlines
Deal found 1/26$559
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/197:39 pm
COU
-
SJD
2 stops17h 15m
American Airlines
Mon 2/234:28 pm
SJD
-
COU
2 stops18h 29m
American Airlines
Deal found 1/26$572
This American Airlines deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/217:27 am
COU
-
PVR
1 stop8h 07m
American Airlines
Fri 8/283:35 pm
PVR
-
COU
1 stop5h 54m
American Airlines
Deal found 1/24$585
This American Airlines deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1112:16 pm
COU
-
PVR
1 stop22h 32m
American Airlines
Thu 9/1711:35 am
PVR
-
COU
1 stop5h 34m
American Airlines
Deal found 1/24$590
This American Airlines deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/237:27 am
COU
-
PVR
1 stop8h 07m
American Airlines
Wed 8/2610:51 am
PVR
-
COU
1 stop10h 38m
American Airlines
Deal found 1/24$655

Find flight deals from Columbia to Mexico

Keep the following information in mind while searching for Columbia to Mexico flight deals. Data was last updated January 27, 2026.

Round-trip from

$407
(American Airlines)
From Columbia Regional to Mexico
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbia to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from Columbia to Mexico that are best for you.

Fly from

Columbia

Fly to

Mexico

Route

Depart

Return

Price

ColumbiaCancún

COU - CUN

COUCUN

Columbia Regional

Sat 2/21

5:41 pm-10:27 am

2 stops15h 46m

Cancun

Tue 2/24

11:30 am-10:40 pm

2 stops12h 10m

$407

ColumbiaCancún

COU - CUN

COUCUN

Columbia Regional

Sun 4/26

7:43 pm-11:57 am

1 stop16h 14m

Cancun

Wed 4/29

11:00 am-7:13 pm

1 stop8h 13m

$442

ColumbiaCancún

COU - CUN

COUCUN

Columbia Regional

Sat 5/23

6:28 pm-1:48 pm

1 stop19h 20m

Cancun

Wed 5/27

7:30 am-7:01 pm

1 stop11h 31m

$465

ColumbiaCancún

COU - CUN

COUCUN

Columbia Regional

Thu 3/19

7:39 pm-4:57 pm

1 stop21h 18m

Cancun

Wed 3/25

7:45 am-7:09 pm

1 stop11h 24m

$513

ColumbiaCancún

COU - CUN

COUCUN

Columbia Regional

Sat 5/23

6:28 pm-1:48 pm

1 stop19h 20m

Cancun

Tue 5/26

7:30 am-4:47 pm

1 stop9h 17m

$515

ColumbiaCancún

COU - CUN

COUCUN

Columbia Regional

Sat 3/21

7:39 pm-4:57 pm

1 stop21h 18m

Cancun

Wed 3/25

11:02 am-7:09 pm

1 stop8h 07m

$541

ColumbiaPuerto Vallarta

COU - PVR

COUPVR

Columbia Regional

Sun 7/19

7:31 pm-12:09 pm

2 stops17h 38m

Puerto Vallarta Ordaz

Fri 7/31

4:05 pm-10:10 am

2 stops17h 05m

$549

ColumbiaPuerto Vallarta

COU - PVR

COUPVR

Columbia Regional

Thu 2/19

6:35 pm-3:47 pm

1 stop21h 12m

Puerto Vallarta Ordaz

Fri 2/27

4:35 pm-10:36 pm

1 stop6h 01m

$559

ColumbiaSan José del Cabo

COU - SJD

COUSJD

Columbia Regional

Thu 2/19

7:39 pm-11:54 am

2 stops17h 15m

San José del Cabo Los Cabos

Mon 2/23

4:28 pm-11:57 am

2 stops18h 29m

$572

ColumbiaPuerto Vallarta

COU - PVR

COUPVR

Columbia Regional

Mon 3/2

9:00 am-1:02 pm

2 stops28h 02m

Puerto Vallarta Ordaz

Wed 3/4

3:40 pm-10:33 am

2 stops18h 53m

$743

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Showing 1-10 of 12 results
1
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Best time to book a flight from Columbia to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from Columbia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbia to Mexico
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Mexico

Get insights into the airlines that provide service to Mexico. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico. Reviews last updated January 27, 2026.
Peruse reviews from past customers who have flown with American Airlines from Columbia to Mexico to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,197 reviews

Boarding

7.5

Entertainment

6.9

Comfort

7.2

Overall

7.2

Crew

8.0

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,197 reviews
American Airlines
7.2
Good
11,197 reviews

Boarding

7.5

Entertainment

6.9

Comfort

7.2

Overall

7.2

Crew

8.0

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Columbia to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Columbia to Mexico?

    Located just 11.1 mi from the city center, Columbia Regional (COU) is the airport most travelers will use when flying to Mexico from Columbia.

  • How long is the flight from Columbia, Missouri to Mexico?

    American Airlines and United Airlines can get you from Columbia, Missouri to Mexico in just under 15h 46m. Your travel time can differ by up to 7h 07m. Airlines will cover a distance of 1268 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Columbia, Missouri to Mexico?

    While some choose either Columbia Regional - Puerto Vallarta Ordaz or Columbia Regional - San José del Cabo Los Cabos, Columbia Regional - Cancun is the most popular route from Columbia, Missouri to Mexico.

  • Can I find deals for flights from Columbia to Mexico that include hotel bookings?

    Yes. In addition to deals on Columbia to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbia to Mexico?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbia to Mexico.

  • Can I find deals for business class flights from Columbia to Mexico?

    Yes. Cheapflights offers flight deals from Columbia to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top airline flying from Columbia to Mexico

Discover the top airline that operate flights from Columbia to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$376Average$566FlexibilityNo cancel feeOn-time71%

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