What are the cheapest airlines flying from Des Moines to Mexico City round-trip?

Flying on Delta is currently your cheapest option to Mexico City, with prices starting at $373. Additional round-trip tickets that might be worth considering are offered by American Airlines and United Airlines, with the lowest prices starting at $527 and $537, respectively. You may be able to fly from Des Moines to Mexico City for 41% less than the average price by searching for these airlines.

What are the cheapest airlines to fly from Des Moines to Mexico City one-way?

$329 is the cheapest one-way deal found within the past few days, from Aeromexico. You may also be able to find cheap deals on Delta and American Airlines, with prices starting from $329 and $379, respectively.

What is the cheapest day to fly from Des Moines to Mexico City?

Travelers seeking maximum savings on their Des Moines to Mexico City flight should consider departing on Thursday mornings when fares are most often at their lowest. Saturday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Mexico City ranges from 0.0 - 4.7 inches per month. July is typically the wettest month, when rainfall can reach 4.7 in. January is typically the driest time to visit Mexico City when rainfall is around 0.0 in.

If weather is an important factor for your trip to Mexico City, use this chart to help with planning. For those seeking warmer temperatures, May is the ideal time of year to visit, when temperatures reach an average of 66.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 55.4 F).

What are the most popular airlines that fly from Des Moines to Mexico City?

When booking a flight from Des Moines to Mexico City, you may want to consider flying on American Airlines, Delta or United Airlines as they are the most popular for this route.

What is the cheapest day to fly round-trip from Des Moines to Mexico City?

Flying to your destination on a Saturday can be more expensive, but this shouldn’t discourage you from finding affordable options to get to Mexico City. Check prices with Cheapflights to find a great deal for your trip.

What is the cheapest month to fly from Des Moines to Mexico City?

August can be a great time to fly to Mexico City from Des Moines with a flight ticket averaging about $641. Cheapflights users have found deals in the month of August for as cheap as $376. The most expensive prices can be found in the month of December.

What is the cheapest time of day to fly from DSM to MEX?

It’s optimal to fly from Des Moines to Mexico City in the morning. By choosing this option you can save up to 16% on the cost of your flight, compared to a flight at noon.

Can I find deals for flights from Des Moines to Mexico City that include hotel bookings?

Yes. In addition to deals on Des Moines to Mexico City flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Des Moines to Mexico City?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Mexico City.

Can I find deals for business class flights from Des Moines to Mexico City?

Yes. Cheapflights offers flight deals from Des Moines to Mexico City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$318+ Flights from Des Moines to Mexico City

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Cheap flight deals from Des Moines to Mexico City

Round-trip from	$346 (Kiwi.com)
One-way from	$318 (Kiwi.com)
Popular in	December
Cheapest in	August
Average price	$609

From Des Moines to Mexico City Benito Juarez

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One-way flight from Des Moines to Mexico City Benito Juarez

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Highest demand for flights based on searches. 12% potential increase in price ($88 potential increase over avg. RT price).

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Cheapest flight prices on average. 3% potential price decrease ($21 potential savings vs. average RT price).

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Average for round-trip flights in September 2025

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Find flight deals from Des Moines to Mexico City

Cheapest flights from Des Moines to Mexico City
Explore the most affordable flight options available from Des Moines to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

Wed 10/152:37 pmDSM - MEX

1 stop27h 23mMultiple Airlines

Tue 10/218:10 amMEX - DSM

1 stop28h 42mMultiple Airlines

Deal found 9/11

$346

Wed 10/152:37 pmDSM - MEX

1 stop27h 23mMultiple Airlines

Wed 10/228:10 amMEX - DSM

1 stop28h 42mMultiple Airlines

Deal found 9/11

$354

Thu 10/162:37 pmDSM - MEX

1 stop27h 23mMultiple Airlines

Tue 10/218:10 amMEX - DSM

1 stop28h 42mMultiple Airlines

Deal found 9/11

$355

Thu 10/162:37 pmDSM - MEX

1 stop27h 23mMultiple Airlines

Wed 10/228:10 amMEX - DSM

1 stop28h 42mMultiple Airlines

Deal found 9/11

$363

Fri 10/172:37 pmDSM - MEX

1 stop27h 23mMultiple Airlines

Tue 10/218:10 amMEX - DSM

1 stop28h 42mMultiple Airlines

Deal found 9/11

$402

Fri 10/172:37 pmDSM - MEX

1 stop27h 23mMultiple Airlines

Wed 10/228:10 amMEX - DSM

1 stop28h 42mMultiple Airlines

Deal found 9/11

$409

Best flights from Des Moines to Mexico City
Discover carefully curated flight deals from Des Moines to Mexico City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2025.

Thu 10/162:37 pmDSM - MEX

1 stop27h 23mMultiple Airlines

Tue 10/218:10 amMEX - DSM

1 stop28h 42mMultiple Airlines

Deal found 9/11

$355

Fri 10/176:04 pmDSM - MEX

2 stops17h 31mMultiple Airlines

Wed 10/228:10 amMEX - DSM

1 stop28h 42mMultiple Airlines

Deal found 9/11

$429

Fri 10/176:04 pmDSM - MEX

2 stops11h 46mMultiple Airlines

Tue 10/218:10 amMEX - DSM

1 stop28h 42mMultiple Airlines

Deal found 9/11

$431

Fri 10/242:37 pmDSM - MEX

1 stop27h 23mMultiple Airlines

Fri 10/3111:00 amMEX - DSM

1 stop10h 37mMultiple Airlines

Deal found 9/9

$467

Sun 10/263:43 pmDSM - MEX

1 stop29h 07mMultiple Airlines

Sun 11/28:10 amMEX - DSM

1 stop29h 37mMultiple Airlines

Deal found 9/11

$484

Sun 10/192:37 pmDSM - MEX

1 stop27h 23mMultiple Airlines

Sun 12/74:10 pmMEX - DSM

2 stops26h 58mMultiple Airlines

Deal found 9/10

$485

Thu 10/232:37 pmDSM - MEX

2 stops32h 23mMultiple Airlines

Mon 11/1011:00 amMEX - DSM

1 stop11h 40mMultiple Airlines

Deal found 9/11

$491

Last-minute flights from Des Moines to Mexico City
Discover last-minute flight deals from Des Moines to Mexico City. Data last updated September 11, 2025 and is based on user searches.

Wed 10/152:37 pmDSM - MEX

1 stop27h 23mMultiple Airlines

Tue 10/218:10 amMEX - DSM

1 stop28h 42mMultiple Airlines

Deal found 9/11

$346

Wed 10/152:37 pmDSM - MEX

1 stop27h 23mMultiple Airlines

Wed 10/228:10 amMEX - DSM

1 stop28h 42mMultiple Airlines

Deal found 9/11

$354

Thu 10/162:37 pmDSM - MEX

1 stop27h 23mMultiple Airlines

Tue 10/218:10 amMEX - DSM

1 stop28h 42mMultiple Airlines

Deal found 9/11

$355

Thu 10/162:37 pmDSM - MEX

1 stop27h 23mMultiple Airlines

Wed 10/228:10 amMEX - DSM

1 stop28h 42mMultiple Airlines

Deal found 9/11

$363

Fri 10/172:37 pmDSM - MEX

1 stop27h 23mMultiple Airlines

Tue 10/218:10 amMEX - DSM

1 stop28h 42mMultiple Airlines

Deal found 9/11

$402

Fri 10/172:37 pmDSM - MEX

1 stop27h 23mMultiple Airlines

Wed 10/228:10 amMEX - DSM

1 stop28h 42mMultiple Airlines

Deal found 9/11

$409

One-way flights from Des Moines to Mexico City
Search for one-way flight options from Des Moines to Mexico City. Find affordable one-way fares based on user searches. Data last updated September 11, 2025.

Sat 11/293:33 pmDSM - MEX

3 stops54h 57mMultiple Airlines

Deal found 9/10

$318

Sat 11/296:17 amDSM - MEX

2 stops12h 38mDelta

Deal found 9/10

$329

Sun 10/265:30 amDSM - MEX

1 stop11h 10mAmerican Airlines

Deal found 9/10

$379

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Mexico City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Thu 10/16

2:37 pm-5:00 pm

1 stop27h 23m

Mexico City Benito Juarez

Tue 10/21

8:10 am-1:52 pm

1 stop28h 42m

$355

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Fri 10/17

6:04 pm-10:35 am

2 stops17h 31m

Mexico City Benito Juarez

Wed 10/22

8:10 am-1:52 pm

1 stop28h 42m

$429

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Fri 10/17

6:04 pm-4:50 am

2 stops11h 46m

Mexico City Benito Juarez

Tue 10/21

8:10 am-1:52 pm

1 stop28h 42m

$431

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Fri 10/24

2:37 pm-5:00 pm

1 stop27h 23m

Mexico City Benito Juarez

Fri 10/31

11:00 am-10:37 pm

1 stop10h 37m

$467

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Sun 10/26

3:43 pm-7:50 pm

1 stop29h 07m

Mexico City Benito Juarez

Sun 11/2

8:10 am-1:47 pm

1 stop29h 37m

$484

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Sun 10/19

2:37 pm-5:00 pm

1 stop27h 23m

Mexico City Benito Juarez

Sun 12/7

4:10 pm-7:08 pm

2 stops26h 58m

$485

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Thu 10/23

2:37 pm-10:00 pm

2 stops32h 23m

Mexico City Benito Juarez

Mon 11/10

11:00 am-10:40 pm

1 stop11h 40m

$491

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Sat 11/29

3:33 pm-10:30 pm

3 stops54h 57m

$318

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Sat 11/29

5:34 am-8:45 pm

1 stop15h 11m

$329

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Sat 11/29

6:17 am-6:55 pm

2 stops12h 38m

$329

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 12 results

Best time to book a flight from Des Moines to Mexico City

Have a flexible travel schedule? Discover the best time to fly to Mexico City from Des Moines with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Mexico City

What is the cheapest month to book a flight from Des Moines to Mexico City?

Currently, May is the cheapest month in which you can book a flight from Des Moines to Mexico City (average of $387). Flying from Des Moines to Mexico City in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Mexico City

Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Des Moines to Mexico City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,960 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,960 reviews

Delta

8.0

Very good

7,960 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

United Airlines

7.4

Good

8,937 reviews

Delta

8.0

Very good

7,960 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,960 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What are the cheapest airlines flying from Des Moines to Mexico City round-trip?
Flying on Delta is currently your cheapest option to Mexico City, with prices starting at $373. Additional round-trip tickets that might be worth considering are offered by American Airlines and United Airlines, with the lowest prices starting at $527 and $537, respectively. You may be able to fly from Des Moines to Mexico City for 41% less than the average price by searching for these airlines.
What are the cheapest airlines to fly from Des Moines to Mexico City one-way?
$329 is the cheapest one-way deal found within the past few days, from Aeromexico. You may also be able to find cheap deals on Delta and American Airlines, with prices starting from $329 and $379, respectively.
Can I find deals for flights from Des Moines to Mexico City that include hotel bookings?
Yes. In addition to deals on Des Moines to Mexico City flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Des Moines to Mexico City?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Mexico City.
Can I find deals for business class flights from Des Moines to Mexico City?
Yes. Cheapflights offers flight deals from Des Moines to Mexico City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Des Moines to Mexico City?
Currently, May is the cheapest month in which you can book a flight from Des Moines to Mexico City (average of $387). Flying from Des Moines to Mexico City in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Other flights to Mexico City

Top 3 airlines flying from Des Moines to Mexico City

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$373	Average$582	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$527	Average$623	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$537	Average$742	FlexibilityNo cancel fee	On-time69%

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$318+ Cheap flights from Des Moines (DSM) to Mexico City (MEX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/29. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Des Moines to Mexico City with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Des Moines to Mexico City

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Des Moines to Mexico City

Cheapest flights from Des Moines to Mexico CityExplore the most affordable flight options available from Des Moines to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

Explore the most affordable flight options available from Des Moines to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Mexico City that are best for you.

Best time to book a flight from Des Moines to Mexico City

Have a flexible travel schedule? Discover the best time to fly to Mexico City from Des Moines with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Mexico City

What is the cheapest month to book a flight from Des Moines to Mexico City?

Reviews of airlines servicing Mexico City

Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Des Moines to Mexico City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Mexico City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Des Moines to Mexico City round-trip?

What are the cheapest airlines to fly from Des Moines to Mexico City one-way?

Can I find deals for flights from Des Moines to Mexico City that include hotel bookings?

How can I find direct flights from Des Moines to Mexico City?

Can I find deals for business class flights from Des Moines to Mexico City?

What is the cheapest month to book a flight from Des Moines to Mexico City?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to Mexico City

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Des Moines to Mexico City

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Book with Flexibility

Travel Smart

Cheapest flights from Des Moines to Mexico City
Explore the most affordable flight options available from Des Moines to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.