What are the cheapest airlines flying from Des Moines to Mexico City round-trip?

Flying on Delta is currently your cheapest option to Mexico City, with prices starting at $373. Additional round-trip tickets that might be worth considering are offered by United Airlines and American Airlines, with the lowest prices starting at $379 and $420, respectively. You may be able to fly from Des Moines to Mexico City for 40% less than the average price by searching for these airlines.

In terms of precipitation, rainfall in Mexico City ranges from 0.0 - 4.7 inches per month. July is typically the wettest month, when rainfall can reach 4.7 in. January is typically the driest time to visit Mexico City when rainfall is around 0.0 in.

If weather is an important factor for your trip to Mexico City, use this chart to help with planning. For those seeking warmer temperatures, May is the ideal time of year to visit, when temperatures reach an average of 66.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 55.4 F).

What are the most popular airlines that fly from Des Moines to Mexico City?

When booking a flight from Des Moines to Mexico City, you may want to consider flying on American Airlines, United Airlines or Delta as they are the most popular for this route.

What is the cheapest time of day to fly from DSM to MEX?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Mexico City as you normally would.

Most accurate provider : When it comes to deals on Des Moines-Mexico City flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Des Moines-Mexico City flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Des Moines-Mexico City flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Des Moines-Mexico City flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Mexico City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Des Moines to Mexico City that include hotel bookings?

Yes. In addition to deals on Des Moines to Mexico City flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Des Moines to Mexico City?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Mexico City.

Can I find deals for business class flights from Des Moines to Mexico City?

Yes. Cheapflights offers flight deals from Des Moines to Mexico City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$203+ Flights from Des Moines to Mexico City

Q: How much does it cost to fly round-trip from Des Moines to Mexico City?

Airfare is below average for this route at the moment. Des Moines to Mexico City flights typically cost between $555 and $740 in January. The cheapest round-trip price found within the last 3 days was $417 on Multiple Airlines (Jan 12-Jan 22).

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1. Tell us where you want to go

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Cheap flight deals from Des Moines to Mexico City

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$417 (Kiwi.com)
One-way from	$203 (Kiwi.com)
Popular in	December
Cheapest in	August
Average price	$690

Provider with most accurate pricing for Des Moines-Mexico City Benito Juarez flight deals.

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Provider most trusted by Cheapflights users for Des Moines-Mexico City Benito Juarez flights.

Search Deals

From Des Moines to Mexico City Benito Juarez

Search Deals

One-way flight from Des Moines to Mexico City Benito Juarez

Search Deals

Highest demand for flights based on searches. 18% potential increase in price ($139 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 4% potential price decrease ($30 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in October 2025

Search Deals

Find flight deals from Des Moines to Mexico City

Cheapest flights from Des Moines to Mexico City
Explore the most affordable flight options available from Des Moines to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

Thu 12/42:56 pmDSM - MEX

2 stops31h 04mMultiple Airlines

Thu 12/1111:55 amMEX - DSM

1 stop30h 43mMultiple Airlines

Deal found 10/28

$447

Wed 11/262:00 pmDSM - MEX

1 stop27h 05mMultiple Airlines

Wed 12/311:55 amMEX - DSM

1 stop27h 36mMultiple Airlines

Deal found 10/27

$469

Thu 12/112:56 pmDSM - MEX

2 stops30h 49mMultiple Airlines

Thu 12/184:45 pmMEX - DSM

1 stop26h 59mMultiple Airlines

Deal found 10/29

$470

Thu 12/411:29 amDSM - MEX

1 stop22h 26mAmerican Airlines

Thu 12/111:45 pmMEX - DSM

1 stop10h 40mAmerican Airlines

Deal found 10/28

$497

Best flights from Des Moines to Mexico City
Discover carefully curated flight deals from Des Moines to Mexico City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 29, 2025.

Mon 1/128:30 amDSM - MEX

1 stop11h 35mMultiple Airlines

Thu 1/2211:00 amMEX - DSM

1 stop28h 40mMultiple Airlines

Deal found 10/28

$417

Sun 3/85:15 pmDSM - MEX

1 stop18h 05mDelta

Wed 3/118:20 amMEX - DSM

2 stops12h 07mDelta

Deal found 10/26

$534

Thu 1/153:04 pmDSM - MEX

1 stop9h 06mUnited Airlines

Sat 1/317:50 amMEX - DSM

1 stop6h 32mUnited Airlines

Deal found 10/27

$549

Wed 11/262:00 pmDSM - MEX

1 stop27h 05mMultiple Airlines

Wed 12/311:55 amMEX - DSM

1 stop27h 36mMultiple Airlines

Deal found 10/27

$469

Thu 12/42:56 pmDSM - MEX

3 stops31h 04mMultiple Airlines

Wed 12/1012:40 amMEX - DSM

2 stops21h 41mMultiple Airlines

Deal found 10/27

$509

Fri 1/98:30 amDSM - MEX

1 stop11h 35mMultiple Airlines

Mon 1/198:10 amMEX - DSM

1 stop11h 21mMultiple Airlines

Deal found 10/28

$524

Mon 12/87:28 pmDSM - MEX

3 stops26h 32mMultiple Airlines

Thu 12/118:10 amMEX - DSM

2 stops14h 11mMultiple Airlines

Deal found 10/27

$526

Fri 12/127:58 pmDSM - MEX

2 stops29h 47mMultiple Airlines

Fri 12/194:45 pmMEX - DSM

1 stop26h 59mMultiple Airlines

Deal found 10/27

$541

Last-minute flights from Des Moines to Mexico City
Discover last-minute flight deals from Des Moines to Mexico City. Data last updated October 29, 2025 and is based on user searches.

Thu 10/305:47 amDSM - MEX

2 stops16h 08mAeromexico

Sun 11/98:40 amMEX - DSM

1 stop9h 06mAeromexico

Deal found 10/29

$603

Fri 11/213:48 pmDSM - MEX

1 stop28h 17mMultiple Airlines

Mon 12/17:30 amMEX - DSM

2 stops15h 33mMultiple Airlines

Deal found 10/28

$582

Mon 11/243:48 pmDSM - MEX

1 stop28h 17mMultiple Airlines

Mon 12/15:35 amMEX - DSM

2 stops17h 28mMultiple Airlines

Deal found 10/27

$521

Mon 11/246:56 pmDSM - MEX

1 stop18h 24mAmerican Airlines

Mon 12/12:20 pmMEX - DSM

1 stop9h 24mAmerican Airlines

Deal found 10/27

$613

Mon 11/248:02 amDSM - MEX

2 stops10h 53mUnited Airlines

Mon 12/112:25 pmMEX - DSM

1 stop9h 55mUnited Airlines

Deal found 10/27

$652

Mon 11/245:35 amDSM - MEX

2 stops16h 50mAeromexico

Mon 12/19:20 pmMEX - DSM

2 stops25h 14mAeromexico

Deal found 10/27

$655

Wed 11/262:00 pmDSM - MEX

1 stop27h 05mMultiple Airlines

Wed 12/311:55 amMEX - DSM

1 stop27h 36mMultiple Airlines

Deal found 10/27

$469

Wed 11/265:35 amDSM - MEX

2 stops17h 20mAeromexico

Wed 12/38:05 pmMEX - DSM

2 stops21h 42mAeromexico

Deal found 10/27

$535

Wed 11/265:35 amDSM - MEX

2 stops13h 55mAeromexico

Tue 12/28:05 amMEX - DSM

2 stops14h 29mAeromexico

Deal found 10/27

$543

Wed 11/265:26 pmDSM - MEX

1 stop16h 29mAmerican Airlines

Tue 12/24:13 pmMEX - DSM

1 stop6h 58mAmerican Airlines

Deal found 10/27

$605

Wed 11/265:14 pmDSM - MEX

2 stops23h 31mUnited Airlines

Tue 12/27:50 amMEX - DSM

1 stop6h 22mUnited Airlines

Deal found 10/27

$658

One-way flights from Des Moines to Mexico City
Search for one-way flight options from Des Moines to Mexico City. Find affordable one-way fares based on user searches. Data last updated October 29, 2025.

Sun 11/238:19 pmDSM - MEX

1 stop20h 46mMultiple Airlines

Deal found 10/28

$203

Mon 12/228:29 pmDSM - MEX

3 stops47h 36mMultiple Airlines

Deal found 10/28

$223

Mon 1/198:25 pmDSM - MEX

2 stops49h 35mMultiple Airlines

Deal found 10/27

$224

Thu 4/236:20 amDSM - MEX

2 stops13h 55mDelta

Deal found 10/27

$274

Fri 11/75:33 amDSM - MEX

1 stop7h 47mAmerican Airlines

Deal found 10/27

$306

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Mexico City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Mon 1/12

8:30 am-8:05 pm

1 stop11h 35m

Mexico City Benito Juarez

Thu 1/22

11:00 am-3:40 pm

1 stop28h 40m

$417

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Wed 11/26

2:00 pm-5:05 pm

1 stop27h 05m

Mexico City Benito Juarez

Wed 12/3

11:55 am-3:31 pm

1 stop27h 36m

$469

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Thu 12/4

2:56 pm-10:00 pm

3 stops31h 04m

Mexico City Benito Juarez

Wed 12/10

12:40 am-10:21 pm

2 stops21h 41m

$509

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Fri 1/9

8:30 am-8:05 pm

1 stop11h 35m

Mexico City Benito Juarez

Mon 1/19

8:10 am-7:31 pm

1 stop11h 21m

$524

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Mon 12/8

7:28 pm-10:00 pm

3 stops26h 32m

Mexico City Benito Juarez

Thu 12/11

8:10 am-10:21 pm

2 stops14h 11m

$526

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Sun 3/8

5:15 pm-10:20 am

1 stop18h 05m

Mexico City Benito Juarez

Wed 3/11

8:20 am-9:27 pm

2 stops12h 07m

$534

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Fri 12/12

7:58 pm-1:45 am

2 stops29h 47m

Mexico City Benito Juarez

Fri 12/19

4:45 pm-7:44 pm

1 stop26h 59m

$541

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Thu 1/15

3:04 pm-12:10 am

1 stop9h 06m

Mexico City Benito Juarez

Sat 1/31

7:50 am-2:22 pm

1 stop6h 32m

$549

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Sun 11/23

8:19 pm-5:05 pm

1 stop20h 46m

$203

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Mon 12/22

8:29 pm-8:05 pm

3 stops47h 36m

$223

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 14 results

Compare providers for flights from Des Moines to Mexico City

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Mexico City in October.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars
AranGrant	Price Accuracy2 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Des Moines-Mexico City flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Des Moines-Mexico City flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Des Moines-Mexico City flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Des Moines-Mexico City flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Mexico City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Mexico City

Have a flexible travel schedule? Discover the best time to fly to Mexico City from Des Moines with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Mexico City

What is the cheapest month to book a flight from Des Moines to Mexico City?

Currently, August is the cheapest month in which you can book a flight from Des Moines to Mexico City (average of $375). Flying from Des Moines to Mexico City in January is currently the most expensive (average of $600). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Des Moines to Mexico City?

Reviews of airlines servicing Mexico City

Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Des Moines to Mexico City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.9

Good

7,992 reviews

Reviews

1 / 20

8.0

Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Delta

7.9

Good

7,992 reviews

Delta

7.9

Good

7,992 reviews

Reviews

1 / 20

8.0

Excellent

Matthew,Oct 2025

GSP - ATL

United Airlines

7.4

Good

8,999 reviews

Delta

7.9

Good

7,992 reviews

Reviews

1 / 20

8.0

Excellent

Matthew,Oct 2025

GSP - ATL

American Airlines

7.2

Good

11,032 reviews

Delta

7.9

Good

7,992 reviews

Reviews

1 / 20

8.0

Excellent

Matthew,Oct 2025

GSP - ATL

Related info for your journey

What are the cheapest airlines flying from Des Moines to Mexico City round-trip?
Flying on Delta is currently your cheapest option to Mexico City, with prices starting at $373. Additional round-trip tickets that might be worth considering are offered by United Airlines and American Airlines, with the lowest prices starting at $379 and $420, respectively. You may be able to fly from Des Moines to Mexico City for 40% less than the average price by searching for these airlines.
Can I find deals for flights from Des Moines to Mexico City that include hotel bookings?
Yes. In addition to deals on Des Moines to Mexico City flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Des Moines to Mexico City?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Mexico City.
Can I find deals for business class flights from Des Moines to Mexico City?
Yes. Cheapflights offers flight deals from Des Moines to Mexico City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Des Moines to Mexico City?
Currently, August is the cheapest month in which you can book a flight from Des Moines to Mexico City (average of $375). Flying from Des Moines to Mexico City in January is currently the most expensive (average of $600). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Other flights to Mexico City

Top 3 airlines flying from Des Moines to Mexico City

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$373	Average$602	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$379	Average$672	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$420	Average$650	FlexibilityNo cancel fee	On-time71%

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$203+ Cheap flights from Des Moines (DSM) to Mexico City (MEX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/23. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Des Moines to Mexico City with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Des Moines to Mexico City

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Des Moines to Mexico City

Cheapest flights from Des Moines to Mexico CityExplore the most affordable flight options available from Des Moines to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

Explore the most affordable flight options available from Des Moines to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Mexico City that are best for you.

Compare providers for flights from Des Moines to Mexico City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Mexico City in October.

Best time to book a flight from Des Moines to Mexico City

Have a flexible travel schedule? Discover the best time to fly to Mexico City from Des Moines with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Mexico City

What is the cheapest month to book a flight from Des Moines to Mexico City?

How much does it cost to fly round-trip from Des Moines to Mexico City?

Reviews of airlines servicing Mexico City

Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Des Moines to Mexico City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Mexico City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Des Moines to Mexico City round-trip?

Can I find deals for flights from Des Moines to Mexico City that include hotel bookings?

How can I find direct flights from Des Moines to Mexico City?

Can I find deals for business class flights from Des Moines to Mexico City?

What is the cheapest month to book a flight from Des Moines to Mexico City?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to Mexico City

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Des Moines to Mexico City

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Book with Flexibility

Travel Smart

Cheapest flights from Des Moines to Mexico City
Explore the most affordable flight options available from Des Moines to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.