What are the cheapest airlines flying from Des Moines to Mexico City round-trip?

Flying on American Airlines is currently your cheapest option to Mexico City, with prices starting at $496. Additional round-trip tickets that might be worth considering are offered by Frontier and Aeromexico, with the lowest prices starting at $513 and $524, respectively. You may be able to fly from Des Moines to Mexico City for 24% less than the average price by searching for these airlines.

What are the cheapest airlines to fly from Des Moines to Mexico City one-way?

$308 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on American Airlines and United Airlines, with prices starting from $327 and $421, respectively.

What is the cheapest day to fly from Des Moines to Mexico City?

Travelers seeking maximum savings on their Des Moines to Mexico City flight should consider departing on Thursday mornings when fares are most often at their lowest. Saturday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Mexico City ranges from 0.0 - 4.7 inches per month. July is typically the wettest month, when rainfall can reach 4.7 in. January is typically the driest time to visit Mexico City when rainfall is around 0.0 in.

If weather is an important factor for your trip to Mexico City, use this chart to help with planning. For those seeking warmer temperatures, May is the ideal time of year to visit, when temperatures reach an average of 66.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 55.4 F).

What are the most popular airlines that fly from Des Moines to Mexico City?

When booking a flight from Des Moines to Mexico City, you may want to consider flying on American Airlines, Delta or United Airlines as they are the most popular for this route.

What is the cheapest day to fly round-trip from Des Moines to Mexico City?

Flying to your destination on a Saturday can be more expensive, but this shouldn’t discourage you from finding affordable options to get to Mexico City. Check prices with Cheapflights to find a great deal for your trip.

What is the cheapest month to fly from Des Moines to Mexico City?

April can be a great time to fly to Mexico City from Des Moines with a flight ticket averaging about $657. Cheapflights users have found deals in the month of April for as cheap as $527. The most expensive prices can be found in the month of December.

What is the cheapest time of day to fly from DSM to MEX?

It’s optimal to fly from Des Moines to Mexico City in the morning. By choosing this option you can save up to 16% on the cost of your flight, compared to a flight at noon.

Can I find deals for flights from Des Moines to Mexico City that include hotel bookings?

Yes. In addition to deals on Des Moines to Mexico City flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Des Moines to Mexico City?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Mexico City.

Can I find deals for business class flights from Des Moines to Mexico City?

Yes. Cheapflights offers flight deals from Des Moines to Mexico City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$206+ Flights from Des Moines to Mexico City

Q: How much does it cost to fly round-trip from Des Moines to Mexico City?

Airfare is typical for this route at the moment. Des Moines to Mexico City flights typically cost between $382 and $817 in September. The cheapest round-trip price found within the last 3 days was $460 on Multiple Airlines (Sep 12-Sep 19).

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Cheap flight deals from Des Moines to Mexico City

Round-trip from	$460 (Mytrip)
One-way from	$206 (Kiwi.com)
Popular in	December
Cheapest in	April
Average price	$572

From Des Moines to Mexico City Benito Juarez

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One-way flight from Des Moines to Mexico City Benito Juarez

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Highest demand for flights based on searches. 10% potential increase in price ($72 potential increase over avg. RT price).

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Cheapest flight prices on average. 2% potential price decrease ($20 potential savings vs. average RT price).

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Average for round-trip flights in July 2025

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Find flight deals from Des Moines to Mexico City

Cheapest flights from Des Moines to Mexico City
Explore the most affordable flight options available from Des Moines to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julho 30, 2025.

sex 9/122:12 pmDSM - MEX

3 stops32h 48mMultiple Airlines

sex 9/1911:45 amMEX - DSM

1 stop9h 44mMultiple Airlines

Deal found 7/29

$460

qua 8/276:13 pmDSM - MEX

1 stop17h 07mAmerican Airlines

qua 9/31:10 pmMEX - DSM

1 stop18h 54mAmerican Airlines

Deal found 7/30

$496

seg 8/253:08 pmDSM - MEX

2 stops31h 52mFrontier

sáb 8/303:10 pmMEX - DSM

2 stops22h 13mFrontier

Deal found 7/29

$513

sáb 9/135:44 amDSM - MEX

1 stop9h 26mAeromexico

sáb 9/208:50 amMEX - DSM

2 stops12h 47mAeromexico

Deal found 7/30

$524

Best flights from Des Moines to Mexico City
Discover carefully curated flight deals from Des Moines to Mexico City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated julho 30, 2025.

sex 9/122:12 pmDSM - MEX

3 stops32h 48mMultiple Airlines

sex 9/1911:45 amMEX - DSM

1 stop9h 44mMultiple Airlines

Deal found 7/29

$460

qua 8/276:13 pmDSM - MEX

1 stop17h 07mAmerican Airlines

qua 9/31:10 pmMEX - DSM

1 stop18h 54mAmerican Airlines

Deal found 7/30

$496

seg 8/253:08 pmDSM - MEX

2 stops31h 52mFrontier

sáb 8/303:10 pmMEX - DSM

2 stops22h 13mFrontier

Deal found 7/29

$513

sáb 9/135:44 amDSM - MEX

1 stop9h 26mAeromexico

sáb 9/208:50 amMEX - DSM

2 stops12h 47mAeromexico

Deal found 7/30

$524

Last-minute flights from Des Moines to Mexico City
Discover last-minute flight deals from Des Moines to Mexico City. Data last updated julho 30, 2025 and is based on user searches.

ter 8/55:35 amDSM - MEX

1 stop9h 55mAmerican Airlines

ter 8/193:30 pmMEX - DSM

1 stop7h 44mAmerican Airlines

Deal found 7/30

$706

ter 8/57:00 amDSM - MEX

2 stops13h 20mDelta

ter 8/197:50 amMEX - DSM

2 stops13h 49mDelta

Deal found 7/30

$755

ter 8/52:21 pmDSM - MEX

2 stops23h 19mMultiple Airlines

seg 8/186:00 amMEX - DSM

2 stops13h 47mMultiple Airlines

Deal found 7/30

$788

ter 8/511:24 amDSM - MEX

1 stop8h 41mAeromexico

seg 8/1112:05 amMEX - DSM

2 stops16h 40mAeromexico

Deal found 7/30

$1,083

ter 8/56:50 pmDSM - MEX

2 stops17h 20mAir Canada

dom 8/1712:15 amMEX - DSM

2 stops33h 24mAir Canada

Deal found 7/30

$1,448

ter 8/125:44 amDSM - MEX

2 stops11h 16mDelta

sex 8/157:35 amMEX - DSM

2 stops14h 04mDelta

Deal found 7/29

$751

sáb 8/166:02 amDSM - MEX

1 stop10h 38mUnited Airlines

ter 8/266:30 amMEX - DSM

1 stop6h 47mUnited Airlines

Deal found 7/30

$686

seg 8/253:08 pmDSM - MEX

2 stops31h 52mFrontier

sáb 8/303:10 pmMEX - DSM

2 stops22h 13mFrontier

Deal found 7/29

$513

ter 8/268:00 amDSM - MEX

2 stops15h 55mAir Canada

sex 9/512:15 amMEX - DSM

2 stops13h 05mAir Canada

Deal found 7/28

$1,143

qua 8/276:13 pmDSM - MEX

1 stop17h 07mAmerican Airlines

qua 9/31:10 pmMEX - DSM

1 stop18h 54mAmerican Airlines

Deal found 7/30

$496

qua 8/275:44 amDSM - MEX

2 stops17h 16mAeromexico

qua 9/38:50 amMEX - DSM

2 stops12h 53mAeromexico

Deal found 7/30

$533

qui 8/282:39 pmDSM - MEX

2 stops20h 01mMultiple Airlines

qui 9/411:45 amMEX - DSM

1 stop9h 56mMultiple Airlines

Deal found 7/30

$525

One-way flights from Des Moines to Mexico City
Search for one-way flight options from Des Moines to Mexico City. Find affordable one-way fares based on user searches. Data last updated julho 30, 2025.

qua 8/62:45 pmDSM - MEX

1 stop30h 15mMultiple Airlines

Deal found 7/29

$206

ter 9/92:12 pmDSM - MEX

1 stop6h 28mDelta

Deal found 7/29

$308

sáb 9/135:10 amDSM - MEX

2 stops10h 20mAmerican Airlines

Deal found 7/30

$327

sáb 9/1311:35 amDSM - MEX

3 stops26h 40mUnited Airlines

Deal found 7/30

$421

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Mexico City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

sex 9/12

2:12 pm-10:00 pm

3 stops32h 48m

Mexico City Benito Juarez

sex 9/19

11:45 am-10:29 pm

1 stop9h 44m

$460

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

qua 8/27

6:13 pm-10:20 am

1 stop17h 07m

Mexico City Benito Juarez

qua 9/3

1:10 pm-9:04 am

1 stop18h 54m

$496

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

seg 8/25

3:08 pm-10:00 pm

2 stops31h 52m

Mexico City Benito Juarez

sáb 8/30

3:10 pm-2:23 pm

2 stops22h 13m

$513

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

sáb 9/13

5:44 am-2:10 pm

1 stop9h 26m

Mexico City Benito Juarez

sáb 9/20

8:50 am-10:37 pm

2 stops12h 47m

$524

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

qua 8/6

2:45 pm-8:00 pm

1 stop30h 15m

$206

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

ter 9/9

2:12 pm-7:40 pm

1 stop6h 28m

$308

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

sáb 9/13

5:10 am-2:30 pm

2 stops10h 20m

$327

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

sáb 9/13

11:35 am-1:15 pm

3 stops26h 40m

$421

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Best time to book a flight from Des Moines to Mexico City

Have a flexible travel schedule? Discover the best time to fly to Mexico City from Des Moines with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Mexico City

What is the cheapest month to book a flight from Des Moines to Mexico City?

Currently, May is the cheapest month in which you can book a flight from Des Moines to Mexico City (average of $388). Flying from Des Moines to Mexico City in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Des Moines to Mexico City?

Reviews of airlines servicing Mexico City

Get a feel of what it's like to fly with Delta, Aeromexico, and United Airlines from Des Moines to Mexico City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,980 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,980 reviews

Delta

8.0

Very good

7,980 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Aeromexico

7.5

Good

1,721 reviews

Delta

8.0

Very good

7,980 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

United Airlines

7.4

Good

8,896 reviews

Delta

8.0

Very good

7,980 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,980 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Frontier

5.9

Fair

3,237 reviews

Delta

8.0

Very good

7,980 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What are the cheapest airlines flying from Des Moines to Mexico City round-trip?
Flying on American Airlines is currently your cheapest option to Mexico City, with prices starting at $496. Additional round-trip tickets that might be worth considering are offered by Frontier and Aeromexico, with the lowest prices starting at $513 and $524, respectively. You may be able to fly from Des Moines to Mexico City for 24% less than the average price by searching for these airlines.
What are the cheapest airlines to fly from Des Moines to Mexico City one-way?
$308 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on American Airlines and United Airlines, with prices starting from $327 and $421, respectively.
Can I find deals for flights from Des Moines to Mexico City that include hotel bookings?
Yes. In addition to deals on Des Moines to Mexico City flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Des Moines to Mexico City?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Mexico City.
Can I find deals for business class flights from Des Moines to Mexico City?
Yes. Cheapflights offers flight deals from Des Moines to Mexico City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Des Moines to Mexico City?
Currently, May is the cheapest month in which you can book a flight from Des Moines to Mexico City (average of $388). Flying from Des Moines to Mexico City in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Other flights to Mexico City

Top 3 airlines flying from Des Moines to Mexico City

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$373	Average$582	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$527	Average$625	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$537	Average$751	FlexibilityNo cancel fee	On-time69%

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$206+ Cheap flights from Des Moines (DSM) to Mexico City (MEX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/6. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Des Moines to Mexico City with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Des Moines to Mexico City

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Des Moines to Mexico City

Cheapest flights from Des Moines to Mexico CityExplore the most affordable flight options available from Des Moines to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julho 30, 2025.

Explore the most affordable flight options available from Des Moines to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julho 30, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Mexico City that are best for you.

Best time to book a flight from Des Moines to Mexico City

Have a flexible travel schedule? Discover the best time to fly to Mexico City from Des Moines with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Mexico City

What is the cheapest month to book a flight from Des Moines to Mexico City?

How much does it cost to fly round-trip from Des Moines to Mexico City?

Reviews of airlines servicing Mexico City

Get a feel of what it's like to fly with Delta, Aeromexico, and United Airlines from Des Moines to Mexico City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Mexico City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Des Moines to Mexico City round-trip?

What are the cheapest airlines to fly from Des Moines to Mexico City one-way?

Can I find deals for flights from Des Moines to Mexico City that include hotel bookings?

How can I find direct flights from Des Moines to Mexico City?

Can I find deals for business class flights from Des Moines to Mexico City?

What is the cheapest month to book a flight from Des Moines to Mexico City?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to Mexico City

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Des Moines to Mexico City

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Book with Flexibility

Travel Smart

Cheapest flights from Des Moines to Mexico City
Explore the most affordable flight options available from Des Moines to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julho 30, 2025.