In terms of precipitation, rainfall in Mexico City Federal District ranges from 0.0 - 4.7 inches per month. July is typically the wettest month, when rainfall can reach 4.7 in. January is typically the driest time to visit Mexico City Federal District when rainfall is around 0.0 in.

If weather is an important factor for your trip to Mexico City Federal District, use this chart to help with planning. For those seeking warmer temperatures, May is the ideal time of year to visit, when temperatures reach an average of 66.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 55.4 F).

What are the most popular airlines that fly from Knoxville to Mexico City Federal District?

The most popular airlines flying from Knoxville to Mexico City Federal District are American Airlines, Aeromexico and Delta. Something to consider prior to booking your flight.

What is the cheapest month to fly from Knoxville to Mexico City Federal District?

Flights from Knoxville to Mexico City Federal District lean towards being more expensive in December. Prices are generally better when you fly from Knoxville to Mexico City Federal District in April, with the cheapest ticket starting at $487.

How can I find direct flights from Knoxville to Mexico City Federal District?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Mexico City Federal District.

Can I find deals for business class flights from Knoxville to Mexico City Federal District?

Yes. Cheapflights offers flight deals from Knoxville to Mexico City Federal District by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$194+ Flights from Knoxville to Mexico City Federal District

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Cheap flight deals from Knoxville to Mexico City Federal District

Round-trip from	$387 (Kiwi.com)
One-way from	$194 (Mytrip)
Popular in	December
Cheapest in	April
Average price	$630

From Knoxville McGhee Tyson to Mexico City Federal District

Search Deals

One-way flight from Knoxville McGhee Tyson to Mexico City Federal District

Search Deals

Highest demand for flights based on searches. 18% potential increase in price ($155 potential increase over avg. RT price).

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Cheapest flight prices on average. 5% potential price decrease ($40 potential savings vs. average RT price).

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Average for round-trip flights in July 2025

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Find flight deals from Knoxville to Mexico City Federal District

Cheapest flights from Knoxville to Mexico City Federal District
Explore the most affordable flight options available from Knoxville to Mexico City Federal District. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.

Thu 10/237:20 amTYS - MEX

1 stop16h 40mMultiple Airlines

Sun 10/2612:40 amMEX - TYS

1 stop20h 08mMultiple Airlines

Deal found 6/30

$387

Mon 8/257:35 pmTYS - MEX

1 stop18h 00mAmerican Airlines

Mon 9/15:00 amMEX - TYS

1 stop16h 50mAmerican Airlines

Deal found 7/1

$520

Fri 8/155:45 amTYS - MEX

2 stops17h 20mAeromexico

Fri 8/227:55 pmMEX - TYS

2 stops22h 11mAeromexico

Deal found 7/1

$524

Mon 7/285:30 amTYS - MEX

2 stops11h 45mDelta

Mon 8/119:10 amMEX - TYS

2 stops12h 38mDelta

Deal found 6/30

$545

Wed 7/237:00 amTYS - MEX

1 stop5h 45mUnited Airlines

Wed 7/306:30 amMEX - TYS

1 stop9h 41mUnited Airlines

Deal found 6/29

$550

Best flights from Knoxville to Mexico City Federal District
Discover carefully curated flight deals from Knoxville to Mexico City Federal District that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 2, 2025.

Thu 10/237:20 amTYS - MEX

1 stop16h 40mMultiple Airlines

Sun 10/2612:40 amMEX - TYS

1 stop20h 08mMultiple Airlines

Deal found 6/30

$387

Mon 8/257:35 pmTYS - MEX

1 stop18h 00mAmerican Airlines

Mon 9/15:00 amMEX - TYS

1 stop16h 50mAmerican Airlines

Deal found 7/1

$520

Fri 8/155:45 amTYS - MEX

2 stops17h 20mAeromexico

Fri 8/227:55 pmMEX - TYS

2 stops22h 11mAeromexico

Deal found 7/1

$524

Mon 7/285:30 amTYS - MEX

2 stops11h 45mDelta

Mon 8/119:10 amMEX - TYS

2 stops12h 38mDelta

Deal found 6/30

$545

Wed 7/237:00 amTYS - MEX

1 stop5h 45mUnited Airlines

Wed 7/306:30 amMEX - TYS

1 stop9h 41mUnited Airlines

Deal found 6/29

$550

Wed 7/235:45 amTYS - MEX

2 stops19h 30mAir Canada

Tue 7/2912:15 amMEX - TYS

2 stops18h 42mAir Canada

Deal found 6/29

$1,282

Fri 8/155:45 amTYS - MEX

2 stops21h 13mWestJet

Thu 8/2112:05 amMEX - TYS

2 stops35h 07mWestJet

Deal found 7/1

$1,335

Last-minute flights from Knoxville to Mexico City Federal District
Discover last-minute flight deals from Knoxville to Mexico City Federal District. Data last updated July 2, 2025 and is based on user searches.

Mon 7/75:30 amTYS - MEX

2 stops21h 28mWestJet

Sun 7/131:55 amMEX - TYS

2 stops17h 21mWestJet

Deal found 6/30

$1,597

Thu 7/102:02 pmTYS - MEX

1 stop8h 43mAmerican Airlines

Tue 7/1511:20 amMEX - TYS

2 stops9h 05mAmerican Airlines

Deal found 6/30

$715

Thu 7/109:55 amTYS - MEX

2 stops15h 20mAir Canada

Mon 7/1412:15 amMEX - TYS

2 stops21h 44mAir Canada

Deal found 6/30

$1,518

Fri 7/116:00 amTYS - MEX

1 stop15h 35mMultiple Airlines

Sat 7/1211:15 pmMEX - TYS

2 stops18h 49mMultiple Airlines

Deal found 6/29

$579

Wed 7/237:00 amTYS - MEX

1 stop5h 45mUnited Airlines

Wed 7/306:30 amMEX - TYS

1 stop9h 41mUnited Airlines

Deal found 6/29

$550

Mon 7/285:30 amTYS - MEX

2 stops11h 45mDelta

Mon 8/119:10 amMEX - TYS

2 stops12h 38mDelta

Deal found 6/30

$545

Fri 8/156:00 amTYS - MEX

1 stop15h 35mMultiple Airlines

Fri 8/226:55 amMEX - TYS

1 stop8h 43mMultiple Airlines

Deal found 7/1

$470

Fri 8/155:45 amTYS - MEX

2 stops17h 20mAeromexico

Fri 8/227:55 pmMEX - TYS

2 stops22h 11mAeromexico

Deal found 7/1

$524

Mon 8/257:35 pmTYS - MEX

1 stop18h 00mAmerican Airlines

Mon 9/15:00 amMEX - TYS

1 stop16h 50mAmerican Airlines

Deal found 7/1

$520

One-way flights from Knoxville to Mexico City Federal District
Search for one-way flight options from Knoxville to Mexico City Federal District. Find affordable one-way fares based on user searches. Data last updated July 2, 2025.

Thu 8/148:52 pmTYS - MEX

2 stops23h 03mMultiple Airlines

Deal found 6/29

$194

Wed 9/32:07 pmTYS - MEX

1 stop8h 38mAmerican Airlines

Deal found 6/30

$292

Cheapflights Fare Finder

Use the filters below to find and compare flights from Knoxville to Mexico City Federal District that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Thu 10/23

7:20 am-10:00 pm

1 stop16h 40m

Mexico City Benito Juarez

Sun 10/26

12:40 am-10:48 pm

1 stop20h 08m

$387

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Mon 8/25

7:35 pm-11:35 am

1 stop18h 00m

Mexico City Benito Juarez

Mon 9/1

5:00 am-11:50 pm

1 stop16h 50m

$520

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Fri 8/15

5:45 am-9:05 pm

2 stops17h 20m

Mexico City Benito Juarez

Fri 8/22

7:55 pm-8:06 pm

2 stops22h 11m

$524

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Mon 7/28

5:30 am-3:15 pm

2 stops11h 45m

Mexico City Benito Juarez

Mon 8/11

9:10 am-11:48 pm

2 stops12h 38m

$545

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Wed 7/23

7:00 am-10:45 am

1 stop5h 45m

Mexico City Benito Juarez

Wed 7/30

6:30 am-6:11 pm

1 stop9h 41m

$550

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Wed 7/23

5:45 am-11:15 pm

2 stops19h 30m

Mexico City Benito Juarez

Tue 7/29

12:15 am-8:57 pm

2 stops18h 42m

$1,282

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Fri 8/15

5:45 am-12:58 am

2 stops21h 13m

Mexico City Benito Juarez

Thu 8/21

12:05 am-1:12 pm

2 stops35h 07m

$1,335

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Thu 8/14

8:52 pm-5:55 pm

2 stops23h 03m

$194

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Wed 9/3

2:07 pm-8:45 pm

1 stop8h 38m

$292

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/29

Best time to book a flight from Knoxville to Mexico City Federal District

Have a flexible travel schedule? Discover the best time to fly to Mexico City Federal District from Knoxville with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Mexico City Federal District

What is the cheapest month to book a flight from Knoxville to Mexico City Federal District?

Currently, May is the cheapest month in which you can book a flight from Knoxville to Mexico City Federal District (average of $388). Flying from Knoxville to Mexico City Federal District in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to DF?

When flying from Knoxville to Mexico City Federal District, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost to fly round-trip from Knoxville to Mexico City Federal District?

Reviews of airlines servicing Mexico City Federal District

Get a feel of what it's like to fly with Delta, Aeromexico, and United Airlines from Knoxville to Mexico City Federal District by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,975 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,975 reviews

Delta

8.0

Very good

7,975 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Aeromexico

7.5

Good

1,718 reviews

Delta

8.0

Very good

7,975 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

United Airlines

7.4

Good

8,861 reviews

Delta

8.0

Very good

7,975 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,975 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

WestJet

7.2

Good

2,912 reviews

Delta

8.0

Very good

7,975 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What airport do you fly from for flights from Knoxville to Mexico City Federal District?
Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Mexico City Federal District. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.
Can I find deals for flights from Knoxville to Mexico City Federal District that include hotel bookings?
Yes. In addition to deals on Knoxville to Mexico City Federal District flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Knoxville to Mexico City Federal District?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Mexico City Federal District.
Can I find deals for business class flights from Knoxville to Mexico City Federal District?
Yes. Cheapflights offers flight deals from Knoxville to Mexico City Federal District by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Knoxville to Mexico City Federal District?
Currently, May is the cheapest month in which you can book a flight from Knoxville to Mexico City Federal District (average of $388). Flying from Knoxville to Mexico City Federal District in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 4 airlines flying from Knoxville to Mexico City Federal District

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$455	Average$749	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$462	Average$592	FlexibilityNo cancel fee	On-timeN/A
Aeromexico	Cheapest$487	Average$642	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$657	Average$657	FlexibilityNo cancel fee	On-time69%

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$194+ Cheap flights from Knoxville (TYS) to Mexico City Federal District

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/14. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Knoxville to Mexico City Federal District with Cheapflights

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Cheap flight deals from Knoxville to Mexico City Federal District

Keep the following information in mind while searching for Knoxville to Mexico City Federal District flight deals. Data was last updated July 2, 2025.

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Knoxville to Mexico City Federal District

Cheapest flights from Knoxville to Mexico City Federal DistrictExplore the most affordable flight options available from Knoxville to Mexico City Federal District. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.

Explore the most affordable flight options available from Knoxville to Mexico City Federal District. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Knoxville to Mexico City Federal District that are best for you.

Best time to book a flight from Knoxville to Mexico City Federal District

Have a flexible travel schedule? Discover the best time to fly to Mexico City Federal District from Knoxville with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Mexico City Federal District

What is the cheapest month to book a flight from Knoxville to Mexico City Federal District?

What is the cheapest time of day to fly from TYS to DF?

Find hourly flight availability from Knoxville to Mexico City Federal District. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 2, 2025.

How much does it cost to fly round-trip from Knoxville to Mexico City Federal District?

Reviews of airlines servicing Mexico City Federal District

Get a feel of what it's like to fly with Delta, Aeromexico, and United Airlines from Knoxville to Mexico City Federal District by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Mexico City Federal District. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Knoxville to Mexico City Federal District?

Can I find deals for flights from Knoxville to Mexico City Federal District that include hotel bookings?

How can I find direct flights from Knoxville to Mexico City Federal District?

Can I find deals for business class flights from Knoxville to Mexico City Federal District?

What is the cheapest month to book a flight from Knoxville to Mexico City Federal District?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Knoxville to Mexico City Federal District

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Knoxville to Mexico City Federal District

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Travel Smart

Cheapest flights from Knoxville to Mexico City Federal District
Explore the most affordable flight options available from Knoxville to Mexico City Federal District. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.