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Mexico City Federal District

$176+ Cheap flights from Knoxville (TYS) to Mexico City Federal District

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/4. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MEX
dic. 6 — dic. 131
sáb. 12/6
sáb. 12/13
1 adult, Economy
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Find flight deals from Knoxville to Mexico City Federal District

Cheapest flights from Knoxville to Mexico City Federal District
Explore the most affordable flight options available from Knoxville to Mexico City Federal District. Find the lowest fares from popular airlines and budget airlines, with prices last updated on noviembre 6, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/46:30 amTYS - MEX
2 stops20h 15mMultiple Airlines
dom. 12/78:10 amMEX - TYS
1 stop30h 47mMultiple Airlines
Deal found 11/5$425
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/114:52 pmTYS - MEX
1 stop25h 13mMultiple Airlines
mar. 1/136:40 amMEX - TYS
2 stops32h 17mMultiple Airlines
Deal found 11/5$475
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/114:52 pmTYS - MEX
1 stop25h 13mMultiple Airlines
lun. 1/1210:00 pmMEX - TYS
2 stops40h 57mMultiple Airlines
Deal found 11/5$484
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/114:52 pmTYS - MEX
1 stop25h 13mMultiple Airlines
jue. 1/157:00 amMEX - TYS
2 stops15h 05mMultiple Airlines
Deal found 11/5$506
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/116:30 amTYS - MEX
1 stop11h 35mMultiple Airlines
mié. 1/146:40 amMEX - TYS
2 stops24h 59mMultiple Airlines
Deal found 11/5$511
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/304:46 pmTYS - MEX
1 stop25h 19mMultiple Airlines
mar. 1/136:40 amMEX - TYS
2 stops32h 17mMultiple Airlines
Deal found 11/5$518
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/304:46 pmTYS - MEX
1 stop25h 19mMultiple Airlines
lun. 1/1210:00 pmMEX - TYS
2 stops40h 57mMultiple Airlines
Deal found 11/5$527

Cheap flight deals from Knoxville to Mexico City Federal District

Keep the following information in mind while searching for Knoxville to Mexico City Federal District flight deals. Data was last updated noviembre 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$425
(Kiwi.com)

One-way from

$176
(Kiwi.com)

Popular in

December

Cheapest in

April

Average price

$657
Provider with most accurate pricing for Knoxville McGhee Tyson-Mexico City Benito Juarez flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Mexico City Benito Juarez flights.
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From Knoxville McGhee Tyson to Mexico City Federal District
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One-way flight from Knoxville McGhee Tyson to Mexico City Federal District
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Highest demand for flights based on searches. 13% potential increase in price ($104 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($18 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Mexico City Federal District that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 6, 2025.
Use the filters below to find and compare flights from Knoxville to Mexico City Federal District that are best for you.

Fly from

Knoxville

Fly to

Mexico City Federal District

Route

Depart

Return

Price

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

jue. 12/11

6:30 am-5:05 pm

1 stop11h 35m

Mexico City Benito Juarez

mié. 1/14

6:40 am-8:39 am

2 stops24h 59m

$511

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

jue. 12/4

6:30 am-5:05 pm

1 stop11h 35m

Mexico City Benito Juarez

dom. 12/7

3:45 pm-9:49 pm

3 stops29h 04m

$524

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

mié. 12/31

11:15 am-9:50 pm

1 stop11h 35m

Mexico City Benito Juarez

lun. 1/12

8:35 am-11:09 pm

2 stops13h 34m

$548

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

mié. 12/31

8:35 am-9:50 pm

1 stop14h 15m

Mexico City Benito Juarez

mié. 1/14

6:40 am-6:52 pm

2 stops11h 12m

$548

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

mié. 12/31

11:15 am-9:50 pm

1 stop11h 35m

Mexico City Benito Juarez

mar. 1/13

6:40 am-8:38 pm

2 stops12h 58m

$548

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

mar. 3/10

8:47 am-7:50 pm

1 stop13h 03m

Mexico City Benito Juarez

mié. 3/11

7:05 am-11:44 pm

2 stops14h 39m

$554

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

mar. 3/10

6:45 am-12:45 pm

1 stop8h 00m

Mexico City Benito Juarez

mié. 3/11

3:45 pm-11:44 pm

1 stop5h 59m

$564

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

sáb. 3/28

8:47 am-4:35 pm

2 stops9h 48m

Mexico City Benito Juarez

lun. 4/6

8:40 am-9:43 pm

2 stops11h 03m

$568

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

jue. 12/4

6:20 pm-9:55 am

1 stop16h 35m

Mexico City Benito Juarez

dom. 12/7

8:00 am-11:50 pm

1 stop14h 50m

$569

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

dom. 3/8

4:30 pm-8:40 pm

1 stop6h 10m

Mexico City Benito Juarez

mié. 3/11

3:30 pm-11:41 pm

1 stop6h 11m

$584

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/6

Showing 1-10 of 15 results
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Best time to book a flight from Knoxville to Mexico City Federal District

Have a flexible travel schedule? Discover the best time to fly to Mexico City Federal District from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Mexico City Federal District

What is the cheapest month to book a flight from Knoxville to Mexico City Federal District?

Currently, September is the cheapest month in which you can book a flight from Knoxville to Mexico City Federal District (average of $271). Flying from Knoxville to Mexico City Federal District in December is currently the most expensive (average of $697). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to DF?

Find hourly flight availability from Knoxville to Mexico City Federal District. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated noviembre 6, 2025.

When flying from Knoxville to Mexico City Federal District, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 37% versus a flight in the afternoon.

How much does it cost to fly round-trip from Knoxville to Mexico City Federal District?

Reviews of airlines servicing Mexico City Federal District

Get insights into the airlines that provide service to Mexico City Federal District. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico City Federal District. Reviews last updated noviembre 6, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Knoxville to Mexico City Federal District by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,001 reviews

Overall

7.9

Food

7.3

Crew

8.5

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,001 reviews
Delta
7.9
Good
8,001 reviews

Overall

7.9

Food

7.3

Crew

8.5

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,007 reviews
Delta
7.9
Good
8,001 reviews

Overall

7.9

Food

7.3

Crew

8.5

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,040 reviews
Delta
7.9
Good
8,001 reviews

Overall

7.9

Food

7.3

Crew

8.5

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Mexico City Federal District. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Mexico City Federal District?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Mexico City Federal District. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • How long is the flight from Knoxville to Mexico City Federal District?

    Delta can get you from Knoxville to Mexico City Federal District in just under 11h 35m. Your travel time can differ by up to . Airlines will cover a distance of 1455 mi.

  • Can I find deals for flights from Knoxville to Mexico City Federal District that include hotel bookings?

    Yes. In addition to deals on Knoxville to Mexico City Federal District flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Mexico City Federal District?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Mexico City Federal District.

  • Can I find deals for business class flights from Knoxville to Mexico City Federal District?

    Yes. Cheapflights offers flight deals from Knoxville to Mexico City Federal District by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Mexico City Federal District?

    Currently, September is the cheapest month in which you can book a flight from Knoxville to Mexico City Federal District (average of $271). Flying from Knoxville to Mexico City Federal District in December is currently the most expensive (average of $697). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Knoxville to Mexico City Federal District

Discover the top 3 airlines that operate flights from Knoxville to Mexico City Federal District. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$318Average$580FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$455Average$722FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$548Average$657FlexibilityNo cancel feeOn-time69%

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