How long is the flight from Knoxville to Mexico City Federal District?

Delta can get you from Knoxville to Mexico City Federal District in just under 8h. Your travel time can differ by up to . Airlines will cover a distance of 1455 mi.

In terms of precipitation, rainfall in Mexico City Federal District ranges from 0.0 - 4.7 inches per month. July is typically the wettest month, when rainfall can reach 4.7 in. January is typically the driest time to visit Mexico City Federal District when rainfall is around 0.0 in.

If weather is an important factor for your trip to Mexico City Federal District, use this chart to help with planning. For those seeking warmer temperatures, May is the ideal time of year to visit, when temperatures reach an average of 66.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 55.4 F).

What are the most popular airlines that fly from Knoxville to Mexico City Federal District?

The most popular airlines flying from Knoxville to Mexico City Federal District are American Airlines, Aeromexico and Delta. Something to consider prior to booking your flight.

How can I find direct flights from Knoxville to Mexico City Federal District?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Mexico City Federal District.

Can I find deals for business class flights from Knoxville to Mexico City Federal District?

Yes. Cheapflights offers flight deals from Knoxville to Mexico City Federal District by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$448+ Cheap Flights from Knoxville to Mexico City Federal District

Q: How much does it cost to fly round-trip from Knoxville to Mexico City Federal District?

Airfare is typical for this route at the moment. Knoxville to Mexico City Federal District flights typically cost between $400 and $565 in October. The cheapest round-trip price found within the last 3 days was $448 on Multiple Airlines (Oct 30-Nov 6).

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Cheap flight deals from Knoxville to Mexico City Federal District

Round-trip from	$448 (Kiwi.com)
Popular in	December
Cheapest in	April
Average price	$562

From Knoxville McGhee Tyson to Mexico City Federal District

Search Deals

Highest demand for flights based on searches. 23% potential increase in price ($212 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 8% potential price decrease ($55 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in September 2025

Search Deals

Find flight deals from Knoxville to Mexico City Federal District

Cheapest flights from Knoxville to Mexico City Federal District
Explore the most affordable flight options available from Knoxville to Mexico City Federal District. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

Thu 10/307:17 pmTYS - MEX

1 stop23h 48mMultiple Airlines

Thu 11/68:10 amMEX - TYS

1 stop9h 12mMultiple Airlines

Deal found 9/15

$448

Tue 10/2111:23 amTYS - MEX

2 stops36h 37mMultiple Airlines

Mon 10/278:10 amMEX - TYS

1 stop9h 22mMultiple Airlines

Deal found 9/16

$467

Wed 10/296:00 pmTYS - MEX

2 stops28h 20mMultiple Airlines

Fri 11/711:10 amMEX - TYS

1 stop11h 04mMultiple Airlines

Deal found 9/15

$487

Thu 10/307:17 pmTYS - MEX

1 stop23h 48mMultiple Airlines

Sun 11/910:00 pmMEX - TYS

2 stops24h 14mMultiple Airlines

Deal found 9/16

$507

Wed 12/312:53 pmTYS - MEX

2 stops34h 07mMultiple Airlines

Sun 12/1411:10 amMEX - TYS

1 stop22h 22mMultiple Airlines

Deal found 9/16

$534

Wed 12/34:22 pmTYS - MEX

1 stop6h 33mAmerican Airlines

Sun 12/146:45 amMEX - TYS

1 stop16h 56mAmerican Airlines

Deal found 9/16

$567

Tue 10/216:15 amTYS - MEX

1 stop16h 00mAmerican Airlines

Mon 10/275:00 amMEX - TYS

1 stop16h 51mAmerican Airlines

Deal found 9/16

$572

Best flights from Knoxville to Mexico City Federal District
Discover carefully curated flight deals from Knoxville to Mexico City Federal District that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 16, 2025.

Thu 10/307:00 amTYS - MEX

2 stops16h 45mMultiple Airlines

Thu 11/68:10 amMEX - TYS

1 stop9h 12mMultiple Airlines

Deal found 9/15

$499

Tue 3/106:45 amTYS - MEX

1 stop8h 00mDelta

Wed 3/113:45 pmMEX - TYS

1 stop5h 59mDelta

Deal found 9/13

$562

Tue 3/108:47 amTYS - MEX

1 stop13h 03mAeromexico

Wed 3/118:05 amMEX - TYS

2 stops11h 38mAeromexico

Deal found 9/13

$562

Tue 10/216:15 amTYS - MEX

1 stop16h 00mAmerican Airlines

Mon 10/275:00 amMEX - TYS

1 stop16h 51mAmerican Airlines

Deal found 9/16

$572

Thu 10/307:17 pmTYS - MEX

1 stop23h 48mMultiple Airlines

Sun 11/910:00 pmMEX - TYS

2 stops24h 14mMultiple Airlines

Deal found 9/16

$507

Wed 12/311:03 amTYS - MEX

2 stops11h 12mAmerican Airlines

Sun 12/146:00 amMEX - TYS

2 stops10h 12mAmerican Airlines

Deal found 9/16

$572

Wed 10/296:00 pmTYS - MEX

1 stop27h 45mMultiple Airlines

Thu 11/612:40 amMEX - TYS

1 stop15h 42mMultiple Airlines

Deal found 9/15

$533

Wed 12/312:53 pmTYS - MEX

2 stops34h 07mMultiple Airlines

Sun 12/1411:10 amMEX - TYS

1 stop22h 22mMultiple Airlines

Deal found 9/16

$534

Last-minute flights from Knoxville to Mexico City Federal District
Discover last-minute flight deals from Knoxville to Mexico City Federal District. Data last updated September 16, 2025 and is based on user searches.

Tue 10/2111:23 amTYS - MEX

2 stops36h 37mMultiple Airlines

Mon 10/278:10 amMEX - TYS

1 stop9h 22mMultiple Airlines

Deal found 9/16

$467

Tue 10/216:15 amTYS - MEX

1 stop16h 00mAmerican Airlines

Mon 10/275:00 amMEX - TYS

1 stop16h 51mAmerican Airlines

Deal found 9/16

$572

Wed 10/296:00 pmTYS - MEX

2 stops28h 20mMultiple Airlines

Fri 11/711:10 amMEX - TYS

1 stop11h 04mMultiple Airlines

Deal found 9/15

$487

Wed 10/294:26 pmTYS - MEX

2 stops29h 19mMultiple Airlines

Wed 11/58:10 amMEX - TYS

1 stop28h 34mMultiple Airlines

Deal found 9/14

$576

Thu 10/307:17 pmTYS - MEX

1 stop23h 48mMultiple Airlines

Thu 11/68:10 amMEX - TYS

1 stop9h 12mMultiple Airlines

Deal found 9/15

$448

Thu 10/307:17 pmTYS - MEX

1 stop23h 48mMultiple Airlines

Sun 11/910:00 pmMEX - TYS

2 stops24h 14mMultiple Airlines

Deal found 9/16

$507

One-way flights from Knoxville to Mexico City Federal District
Search for one-way flight options from Knoxville to Mexico City Federal District. Find affordable one-way fares based on user searches. Data last updated September 16, 2025.

Sun 10/56:30 amTYS - MEX

1 stop7h 03mAmerican Airlines

Deal found 9/15

$534

Sun 10/55:45 amTYS - MEX

2 stops10h 40mDelta

Deal found 9/15

$694

Sun 10/512:01 pmTYS - MEX

3 stops38h 14mMultiple Airlines

Deal found 9/15

$2,355

Cheapflights Fare Finder

Use the filters below to find and compare flights from Knoxville to Mexico City Federal District that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Thu 10/30

7:00 am-9:45 pm

2 stops16h 45m

Mexico City Benito Juarez

Thu 11/6

8:10 am-6:22 pm

1 stop9h 12m

$499

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Thu 10/30

7:17 pm-5:05 pm

1 stop23h 48m

Mexico City Benito Juarez

Sun 11/9

10:00 pm-11:14 pm

2 stops24h 14m

$507

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Wed 10/29

6:00 pm-7:45 pm

1 stop27h 45m

Mexico City Benito Juarez

Thu 11/6

12:40 am-5:22 pm

1 stop15h 42m

$533

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Wed 12/3

12:53 pm-10:00 pm

2 stops34h 07m

Mexico City Benito Juarez

Sun 12/14

11:10 am-10:32 am

1 stop22h 22m

$534

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Tue 3/10

6:45 am-12:45 pm

1 stop8h 00m

Mexico City Benito Juarez

Wed 3/11

3:45 pm-11:44 pm

1 stop5h 59m

$562

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Tue 3/10

8:47 am-7:50 pm

1 stop13h 03m

Mexico City Benito Juarez

Wed 3/11

8:05 am-9:43 pm

2 stops11h 38m

$562

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Tue 10/21

6:15 am-8:15 pm

1 stop16h 00m

Mexico City Benito Juarez

Mon 10/27

5:00 am-11:51 pm

1 stop16h 51m

$572

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Wed 12/3

11:03 am-9:15 pm

2 stops11h 12m

Mexico City Benito Juarez

Sun 12/14

6:00 am-5:12 pm

2 stops10h 12m

$572

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Sun 10/5

6:30 am-11:33 am

1 stop7h 03m

$534

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Sun 10/5

5:45 am-2:25 pm

2 stops10h 40m

$694

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 11 results

Best time to book a flight from Knoxville to Mexico City Federal District

Have a flexible travel schedule? Discover the best time to fly to Mexico City Federal District from Knoxville with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Mexico City Federal District

What is the cheapest month to book a flight from Knoxville to Mexico City Federal District?

Currently, May is the cheapest month in which you can book a flight from Knoxville to Mexico City Federal District (average of $387). Flying from Knoxville to Mexico City Federal District in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to DF?

When flying from Knoxville to Mexico City Federal District, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost to fly round-trip from Knoxville to Mexico City Federal District?

Reviews of airlines servicing Mexico City Federal District

Get a feel of what it's like to fly with Delta, Aeromexico, and American Airlines from Knoxville to Mexico City Federal District by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,957 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,957 reviews

Delta

8.0

Very good

7,957 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Aeromexico

7.5

Good

1,696 reviews

Delta

8.0

Very good

7,957 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,957 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What airport do you fly from for flights from Knoxville to Mexico City Federal District?
Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Mexico City Federal District. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.
How long is the flight from Knoxville to Mexico City Federal District?
Delta can get you from Knoxville to Mexico City Federal District in just under 8h. Your travel time can differ by up to . Airlines will cover a distance of 1455 mi.
Can I find deals for flights from Knoxville to Mexico City Federal District that include hotel bookings?
Yes. In addition to deals on Knoxville to Mexico City Federal District flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Knoxville to Mexico City Federal District?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Mexico City Federal District.
Can I find deals for business class flights from Knoxville to Mexico City Federal District?
Yes. Cheapflights offers flight deals from Knoxville to Mexico City Federal District by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Knoxville to Mexico City Federal District?
Currently, May is the cheapest month in which you can book a flight from Knoxville to Mexico City Federal District (average of $387). Flying from Knoxville to Mexico City Federal District in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Knoxville to Mexico City Federal District

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$455	Average$698	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$462	Average$582	FlexibilityNo cancel fee	On-timeN/A
Aeromexico	Cheapest$487	Average$837	FlexibilityNo cancel fee	On-timeN/A

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$448+ Cheap flights from Knoxville (TYS) to Mexico City Federal District

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/30. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Knoxville to Mexico City Federal District with Cheapflights

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2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Knoxville to Mexico City Federal District

Keep the following information in mind while searching for Knoxville to Mexico City Federal District flight deals. Data was last updated September 16, 2025.

Round-trip from

Popular in

Cheapest in

Average price

Find flight deals from Knoxville to Mexico City Federal District

Cheapest flights from Knoxville to Mexico City Federal DistrictExplore the most affordable flight options available from Knoxville to Mexico City Federal District. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

Explore the most affordable flight options available from Knoxville to Mexico City Federal District. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Knoxville to Mexico City Federal District that are best for you.

Best time to book a flight from Knoxville to Mexico City Federal District

Have a flexible travel schedule? Discover the best time to fly to Mexico City Federal District from Knoxville with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Mexico City Federal District

What is the cheapest month to book a flight from Knoxville to Mexico City Federal District?

What is the cheapest time of day to fly from TYS to DF?

Find hourly flight availability from Knoxville to Mexico City Federal District. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

How much does it cost to fly round-trip from Knoxville to Mexico City Federal District?

Reviews of airlines servicing Mexico City Federal District

Get a feel of what it's like to fly with Delta, Aeromexico, and American Airlines from Knoxville to Mexico City Federal District by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Mexico City Federal District. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Knoxville to Mexico City Federal District?

How long is the flight from Knoxville to Mexico City Federal District?

Can I find deals for flights from Knoxville to Mexico City Federal District that include hotel bookings?

How can I find direct flights from Knoxville to Mexico City Federal District?

Can I find deals for business class flights from Knoxville to Mexico City Federal District?

What is the cheapest month to book a flight from Knoxville to Mexico City Federal District?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Knoxville to Mexico City Federal District

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Knoxville to Mexico City Federal District

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Book with Flexibility

Travel Smart

Cheapest flights from Knoxville to Mexico City Federal District
Explore the most affordable flight options available from Knoxville to Mexico City Federal District. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.