What are the cheapest airlines to fly from Medford to Mesa one-way?

The cheapest airlines for a one-way flight from Medford to Mesa are Delta ($112), Alaska Airlines ($149), and American Airlines ($220).

Weekly flight availability from Medford to Mesa

The most flights from MFR to MS9 are scheduled on a Monday (4 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (1 on average).

In terms of precipitation, rainfall in Mesa ranges from 0.0 - 1.1 inches per month. July is typically the wettest month, when rainfall can reach 1.1 in. June is typically the driest time to visit Mesa when rainfall is around 0.0 in.

If weather is an important factor for your trip to Mesa, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 95.0 F. Travelers looking to avoid the cold should look outside of December, when temperatures are typically at their lowest (around 55.4 F).

What are the cheapest flights from Medford to Mesa?

On average you can expect to pay $467 for a flight from Medford to Mesa. The cheapest flight overall is $193 while the most popular route, (Medford - Phoenix Sky Harbor Intl) is currently priced at $162.

What are the most reliable airlines from Medford to Mesa?

Consider Porter Airlines (90%), Alaska Airlines (89%) or SkyWest Airlines (79%) when booking your flight. These represent the most reliable airlines when flying from Medford to Mesa.

What are the most popular airlines that fly from Medford to Mesa?

Before booking your flight from Medford to Mesa check out the most popular airlines for this route: American Airlines, Alaska Airlines or Delta.

What airport do you fly from for flights from Medford to Mesa?

If you book a flight to Mesa from Medford, you will be flying from Medford, which is the city’s only airport. Medford (MFR) is located 3.0 mi from the center of Medford. There are 2 flights from Medford to Mesa per day from 3 different airlines.

Can I find deals for flights from Medford to Mesa that include hotel bookings?

Yes. In addition to deals on Medford to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Medford to Mesa?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to Mesa.

Can I find deals for business class flights from Medford to Mesa?

Yes. Cheapflights offers flight deals from Medford to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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Cheapflights Tip: The best prices from Medford to Mesa are usually found in January or April, booked 45 days in advance, depart on a Thursday or Tuesday and return on a Tuesday

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Popular in	August
Cheapest in	January
Average price	$533

Highest demand for flights based on searches. 7% potential increase in price ($38 potential increase over avg. RT price).

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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).

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Average for round-trip flights in October 2026

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Everything you need to know about your flight from Medford to Mesa

Prices

Airlines

What is the cheapest time of day to fly from MFR to MS9?

One of the essential ways to save on airfare from Medford to Mesa is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the afternoon could potentially save you up to 12% on airfare.

Reviews of airlines servicing Mesa

Get a feel of what it's like to fly with Alaska Airlines,Delta, andAmerican Airlines from Medford to Mesa by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Alaska Airlines

7.9

Good

13,059 reviews

Reviews

1 / 20

8.0

Excellent

Eugene,Mar 2026

MFR - SEA

Alaska Airlines is is always good. There where few choices of what to drink, and no food. No blankets, no pillows, and you h ats ok. I just had open heart surgery And i could have used something. But the flight and the crew where exelent. So all is well

Alaska Airlines

7.9

Good

13,059 reviews

Alaska Airlines

7.9

Good

13,059 reviews

Reviews

1 / 20

8.0

Excellent

Eugene,Mar 2026

MFR - SEA

Delta

7.8

Good

8,649 reviews

Alaska Airlines

7.9

Good

13,059 reviews

Reviews

1 / 20

8.0

Excellent

Eugene,Mar 2026

MFR - SEA

American Airlines

7.0

Good

12,162 reviews

Alaska Airlines

7.9

Good

13,059 reviews

Reviews

1 / 20

8.0

Excellent

Eugene,Mar 2026

MFR - SEA

Related info for your journey

What airport do you fly from for flights from Medford to Mesa?
If you book a flight to Mesa from Medford, you will be flying from Medford, which is the city’s only airport. Medford (MFR) is located 3.0 mi from the center of Medford. There are 2 flights from Medford to Mesa per day from 3 different airlines.
What are the cheapest airlines to fly from Medford to Mesa one-way?
The cheapest airlines for a one-way flight from Medford to Mesa are Delta ($112), Alaska Airlines ($149), and American Airlines ($220).
What are the most reliable airlines from Medford to Mesa?
Consider Porter Airlines (90%), Alaska Airlines (89%) or SkyWest Airlines (79%) when booking your flight. These represent the most reliable airlines when flying from Medford to Mesa.
What are the cheapest flights from Medford to Mesa?
On average you can expect to pay $467 for a flight from Medford to Mesa. The cheapest flight overall is $193 while the most popular route, (Medford - Phoenix Sky Harbor Intl) is currently priced at $162.
Can I find deals for flights from Medford to Mesa that include hotel bookings?
Yes. In addition to deals on Medford to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Medford to Mesa?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to Mesa.
Can I find deals for business class flights from Medford to Mesa?
Yes. Cheapflights offers flight deals from Medford to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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Top 3 airlines flying from Medford to Mesa

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$117	Average$253	FlexibilityNo cancel fee	On-timeN/A
Alaska Airlines	Cheapest$251	Average$487	FlexibilityNo cancel fee	On-time75%
American Airlines	Cheapest$385	Average$494	FlexibilityNo cancel fee	On-time71%

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Cheap flights from Medford (MFR) to Mesa, AZ

Find cheap flights from Medford to Mesa with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Find flight deals from Medford to Mesa

Popular in

Cheapest in

Average price

Cheapflights Insights

What is the cheapest time of day to fly from MFR to MS9?

One of the essential ways to save on airfare from Medford to Mesa is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the afternoon could potentially save you up to 12% on airfare.

Weekly flight availability from Medford to Mesa

The most flights from MFR to MS9 are scheduled on a Monday (4 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (1 on average).

Reviews of airlines servicing Mesa

Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated October 13, 2026.

Get a feel of what it's like to fly with Alaska Airlines,Delta, andAmerican Airlines from Medford to Mesa by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

What airport do you fly from for flights from Medford to Mesa?

What are the cheapest airlines to fly from Medford to Mesa one-way?

What are the most reliable airlines from Medford to Mesa?

What are the cheapest flights from Medford to Mesa?

Can I find deals for flights from Medford to Mesa that include hotel bookings?

How can I find direct flights from Medford to Mesa?

Can I find deals for business class flights from Medford to Mesa?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Medford to Mesa

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Complete your trip

Complete your trip to Mesa by adding a car rental and/or hotel reservation to your travel itinerary.

Search flights from Medford to Mesa by cabin class

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Medford and Mesa flights

Browse other Medford and Mesa flight options. Last updated on October 13, 2026.

Other flights from Medford

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Top 3 airlines flying from Medford to Mesa

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