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$85+ Cheap flights from Knoxville (TYS) to Mesa, AZ

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/10. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — PHX
Jul 8 — Jul 151
Tue 7/8
Tue 7/15
1 adult, Economy
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Cheapflights Tip: The best prices from Knoxville McGhee Tyson to Mesa are usually found in January or July, booked 59 days in advance, depart on a Tuesday or Sunday and return on a Tuesday

Cheap flight deals from Knoxville to Mesa

Keep the following information in mind while searching for Knoxville to Mesa flight deals. Data was last updated July 3, 2025.

Round-trip from

$107
(Gotogate)

One-way from

$85
(Mytrip)

Popular in

February

Cheapest in

January

Average price

$244
From Knoxville McGhee Tyson to Mesa
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One-way flight from Knoxville McGhee Tyson to Mesa
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High demand for flights, 1% potential price rise
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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Knoxville to Mesa

Cheapest flights from Knoxville to Mesa
Explore the most affordable flight options available from Knoxville to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

This Gotogate deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/176:00 amTYS - PHX
Nonstop4h 15mAllegiant Air
Sun 8/243:57 pmPHX - TYS
Nonstop3h 27mAllegiant Air
Deal found 7/3$107
This Flightnetwork deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/175:25 pmTYS - PHX
1 stop8h 59mFrontier
Sun 8/247:09 amPHX - TYS
1 stop9h 32mFrontier
Deal found 7/3$174
This Cheapflightsfares deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/188:26 pmTYS - PHX
1 stop6h 01mMultiple Airlines
Thu 9/254:19 pmPHX - TYS
Nonstop3h 31mMultiple Airlines
Deal found 7/3$197
This American Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/73:03 pmTYS - PHX
1 stop8h 58mAmerican Airlines
Wed 10/2212:35 pmPHX - TYS
1 stop7h 32mAmerican Airlines
Deal found 7/3$251
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/187:30 amTYS - PHX
1 stop9h 32mDelta
Thu 12/43:05 pmPHX - TYS
1 stop5h 54mDelta
Deal found 7/1$273

Cheapflights Fare Finder

Customize your flight search to find flights from Knoxville to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
Use the filters below to find and compare flights from Knoxville to Mesa that are best for you.

Fly from

Knoxville

Fly to

Mesa

Route

Depart

Return

Price

KnoxvillePhoenix

TYS - PHX

TYSPHX

Knoxville McGhee Tyson

Sun 8/17

6:00 am-7:15 am

Nonstop4h 15m

Phoenix Sky Harbor Intl

Sun 8/24

3:57 pm-10:24 pm

Nonstop3h 27m

$107

KnoxvillePhoenix

TYS - PHX

TYSPHX

Knoxville McGhee Tyson

Sun 8/17

5:25 pm-11:24 pm

1 stop8h 59m

Phoenix Sky Harbor Intl

Sun 8/24

7:09 am-7:41 pm

1 stop9h 32m

$174

KnoxvillePhoenix

TYS - PHX

TYSPHX

Knoxville McGhee Tyson

Thu 9/18

8:26 pm-11:27 pm

1 stop6h 01m

Phoenix Sky Harbor Intl

Thu 9/25

4:19 pm-10:50 pm

Nonstop3h 31m

$197

KnoxvillePhoenix

TYS - PHX

TYSPHX

Knoxville McGhee Tyson

Tue 8/26

12:56 pm-6:22 pm

1 stop8h 26m

Phoenix Sky Harbor Intl

Mon 9/1

5:00 am-1:36 pm

1 stop5h 36m

$270

KnoxvillePhoenix

TYS - PHX

TYSPHX

Knoxville McGhee Tyson

Mon 7/21

7:43 pm-10:45 pm

1 stop6h 02m

Phoenix Sky Harbor Intl

Tue 7/29

11:59 pm-11:08 am

1 stop8h 09m

$298

KnoxvillePhoenix

TYS - PHX

TYSPHX

Knoxville McGhee Tyson

Tue 7/29

7:00 am-11:02 am

1 stop7h 02m

Phoenix Sky Harbor Intl

Tue 8/5

12:09 pm-11:27 pm

1 stop8h 18m

$341

KnoxvillePhoenix

TYS - PHX

TYSPHX

Knoxville McGhee Tyson

Sun 8/10

6:00 am-6:49 am

Nonstop3h 49m

$85

KnoxvillePhoenix

TYS - PHX

TYSPHX

Knoxville McGhee Tyson

Sun 8/10

5:25 pm-11:24 pm

1 stop8h 59m

$92

KnoxvillePhoenix

TYS - PHX

TYSPHX

Knoxville McGhee Tyson

Wed 9/17

6:00 am-10:59 am

1 stop7h 59m

$126

KnoxvillePhoenix

TYS - PHX

TYSPHX

Knoxville McGhee Tyson

Fri 8/1

11:01 am-5:08 pm

1 stop9h 07m

$142

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Showing 1-10 of 12 results
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Best time to book a flight from Knoxville to Mesa

Have a flexible travel schedule? Discover the best time to fly to Mesa from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Mesa

How far ahead should I book a flight from Knoxville to Mesa?

Use this chart to determine the optimal time to book a round-trip flight from Knoxville to Mesa. Price data was last updated on June 27, 2025.

Booking 59 days in advance of your planned departure date is, on average, the best time to get cheap flights from Knoxville to Mesa. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Knoxville to Mesa?

Currently, January is the cheapest month in which you can book a flight from Knoxville to Mesa (average of $258). Flying from Knoxville to Mesa in March is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to MS9?

Find hourly flight availability from Knoxville to Mesa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 3, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Knoxville to Mesa as you normally would.

What is the cheapest day to fly from Knoxville to Mesa?

Use this chart to determine the cheapest time to fly round-trip from Knoxville to Mesa. Price data was last updated on November 18, 2024.

Travelers seeking maximum savings on their Knoxville to Mesa flight should consider departing on Monday at noon when fares are most often at their lowest. Thursday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Mesa

Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated July 3, 2025.
Peruse reviews from past customers who have flown with Alaska Airlines, Delta, and United Airlines from Knoxville to Mesa to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Food

7.1

Crew

8.5

Comfort

7.8

Entertainment

7.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Food

7.1

Crew

8.5

Comfort

7.8

Entertainment

7.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,982 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Food

7.1

Crew

8.5

Comfort

7.8

Entertainment

7.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,861 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Food

7.1

Crew

8.5

Comfort

7.8

Entertainment

7.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Allegiant Air
7.3
Good
708 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Food

7.1

Crew

8.5

Comfort

7.8

Entertainment

7.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Food

7.1

Crew

8.5

Comfort

7.8

Entertainment

7.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Mesa?

    For a flight from Knoxville to Mesa, you will be flying from McGhee Tyson. Knoxville McGhee Tyson (TYS) is just 11.3 mi from the center of the city. McGhee Tyson is the only Knoxville airport and it handles 0 outbound flights to Mesa per day. 5 airlines have flights to Mesa from Knoxville McGhee Tyson on a regular basis.

  • What are the cheapest airlines to fly from Knoxville to Mesa one-way?

    $85 is the cheapest one-way deal found within the past few days, from Allegiant Air. You may also be able to find cheap deals on Frontier and American Airlines, with prices starting from $92 and $126, respectively.

  • What are the cheapest flights from Knoxville to Mesa?

    Looking for the cheapest flight from Knoxville to Mesa? While on average our users pay $154, our data indicates the cheapest price to be $60. The most popular route (Knoxville McGhee Tyson - Phoenix Sky Harbor Intl), is priced around $129.

  • Can I find deals for flights from Knoxville to Mesa that include hotel bookings?

    Yes. In addition to deals on Knoxville to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Mesa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Mesa.

  • Can I find deals for business class flights from Knoxville to Mesa?

    Yes. Cheapflights offers flight deals from Knoxville to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Mesa?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to Mesa (average of $258). Flying from Knoxville to Mesa in March is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 5 airlines flying from Knoxville to Mesa

Discover the top 5 airlines that operate flights from Knoxville to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$116Average$232FlexibilityNo cancel feeOn-time88%
DeltaCheapest$128Average$441FlexibilityNo cancel feeOn-timeN/A
FrontierCheapest$137Average$266FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$228Average$570FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$271Average$493FlexibilityNo cancel feeOn-time71%

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