$125+ Cheap flights from Knoxville (TYS) to Mesa, AZ
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/2. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — PHX
Oct 19 — Oct 261
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Mesa with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Knoxville McGhee Tyson to Mesa are usually found in August or January, booked 36 days in advance, depart on a Friday or Wednesday and return on a Wednesday
Cheap flight deals from Knoxville to Mesa
Cheapest
Best
Last-minute
One-way
Cheapest flights from Knoxville to MesaExplore the most affordable flight options available from Knoxville to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 19, 2026.
Explore the most affordable flight options available from Knoxville to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 19, 2026.
This CheapOair deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:52 pm -
Nonstop4h 01m
Sun 11/14:43 pm -
Nonstop3h 27m
Deal found 9/14![Allegiant Air logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:30 am -
1 stop20h 12m
Sun 11/153:20 pm -
Nonstop3h 36m
Deal found 9/17![Multiple Airlines logo]()
$251
This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:00 am -
Nonstop4h 01m
Mon 10/199:11 am -
Nonstop3h 27m
Deal found 9/14![Allegiant Air logo]()
$255
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:16 pm -
1 stop7h 05m
Tue 10/2710:25 pm -
1 stop8h 55m
Deal found 9/16![Delta logo]()
$261
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:58 pm -
1 stop7h 01m
Tue 10/1311:09 pm -
1 stop6h 23m
Deal found 9/14![American Airlines logo]()
$266
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:20 pm -
1 stop7h 30m
Wed 10/2810:05 am -
2 stops8h 00m
Deal found 9/16![Southwest logo]()
$267
This Cheapflightsfares deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/121:39 pm -
Nonstop4h 01m
Sun 11/153:20 pm -
Nonstop3h 36m
Deal found 9/17![Allegiant Air logo]()
$271
This CheapOair deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:00 am -
Nonstop4h 01m
Mon 10/199:11 am -
Nonstop3h 27m
Deal found 9/15![Allegiant Air logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:30 am -
1 stop28h 34m
Sun 11/153:20 pm -
Nonstop3h 36m
Deal found 9/18![Multiple Airlines logo]()
$278
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:16 pm -
1 stop7h 05m
Mon 10/2611:32 pm -
1 stop8h 22m
Deal found 9/16![Delta logo]()
$279
Best flights from Knoxville to MesaDiscover carefully curated flight deals from Knoxville to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 19, 2026.
Discover carefully curated flight deals from Knoxville to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 19, 2026.
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/282:40 pm -
1 stop6h 55m
Tue 2/28:45 am -
2 stops7h 55m
Deal found 9/14![Southwest logo]()
$287
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:23 pm -
1 stop6h 58m
Mon 11/211:25 pm -
1 stop8h 55m
Deal found 9/17![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2110:42 am -
2 stops13h 07m
Tue 10/276:00 am -
2 stops13h 32m
Deal found 9/16![United Airlines logo]()
$372
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:25 pm -
1 stop7h 55m
Mon 11/95:40 am -
2 stops7h 20m
Deal found 9/19![Southwest logo]()
$359
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:15 am -
2 stops7h 35m
Wed 10/2810:05 am -
2 stops8h 00m
Deal found 9/16![Southwest logo]()
$361
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2310:42 am -
1 stop9h 53m
Mon 11/27:37 pm -
2 stops12h 16m
Deal found 9/17![United Airlines logo]()
$424
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:25 pm -
2 stops7h 05m
Mon 10/195:00 am -
1 stop13h 35m
Deal found 9/14![Southwest logo]()
$366
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2210:42 am -
1 stop9h 53m
Sat 10/246:00 am -
2 stops12h 01m
Deal found 9/16![United Airlines logo]()
$425
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:25 pm -
2 stops7h 05m
Sun 10/256:05 am -
1 stop6h 30m
Deal found 9/15![Southwest logo]()
$373
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/131:00 pm -
2 stops9h 55m
Tue 10/205:45 am -
1 stop11h 25m
Deal found 9/15![Southwest logo]()
$405
Last-minute flights from Knoxville to MesaDiscover last-minute flight deals from Knoxville to Mesa. Data last updated September 19, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Mesa. Data last updated September 19, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/242:34 pm -
Nonstop3h 58m
Sat 10/33:38 pm -
Nonstop3h 27m
Deal found 9/17![Allegiant Air logo]()
$284
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:58 pm -
1 stop7h 01m
Tue 10/1311:09 pm -
1 stop6h 23m
Deal found 9/14![American Airlines logo]()
$266
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:58 pm -
1 stop7h 01m
Mon 10/1211:50 pm -
1 stop6h 48m
Deal found 9/15![American Airlines logo]()
$291
This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:00 am -
Nonstop4h 01m
Mon 10/199:11 am -
Nonstop3h 27m
Deal found 9/14![Allegiant Air logo]()
$255
This CheapOair deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:00 am -
Nonstop4h 01m
Mon 10/199:11 am -
Nonstop3h 27m
Deal found 9/15![Allegiant Air logo]()
$274
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:16 pm -
1 stop7h 05m
Tue 10/2710:25 pm -
1 stop8h 55m
Deal found 9/16![Delta logo]()
$261
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:20 pm -
1 stop7h 30m
Wed 10/2810:05 am -
2 stops8h 00m
Deal found 9/16![Southwest logo]()
$267
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:16 pm -
1 stop7h 05m
Mon 10/2611:32 pm -
1 stop8h 22m
Deal found 9/16![Delta logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/259:29 pm -
1 stop17h 48m
Sun 11/14:43 pm -
Nonstop3h 27m
Deal found 9/17![Multiple Airlines logo]()
$295
This CheapOair deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:52 pm -
Nonstop4h 01m
Sun 11/14:43 pm -
Nonstop3h 27m
Deal found 9/14![Allegiant Air logo]()
$242
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:25 pm -
2 stops7h 10m
Sat 12/56:20 am -
2 stops9h 20m
Deal found 9/17![Southwest logo]()
$289
One-way flights from Knoxville to MesaSearch for one-way flight options from Knoxville to Mesa. Find affordable one-way fares based on user searches. Data last updated September 19, 2026.
Search for one-way flight options from Knoxville to Mesa. Find affordable one-way fares based on user searches. Data last updated September 19, 2026.
This CheapOair deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:30 am -
Nonstop4h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Allegiant Air logo]()
$125
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:16 pm -
1 stop7h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Delta logo]()
$131
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:15 pm -
1 stop8h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Southwest logo]()
$133
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:45 am -
2 stops8h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![United Airlines logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1512:29 pm -
Nonstop4h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Allegiant Air logo]()
$145
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:58 pm -
1 stop7h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![American Airlines logo]()
$149
This Super.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/242:34 pm -
Nonstop3h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Allegiant Air logo]()
$150
Find flight deals from Knoxville to Mesa
Keep the following information in mind while searching for Knoxville to Mesa flight deals. Data was last updated September 19, 2026.
Round-trip from | $242 (CheapOair) |
|---|---|
One-way from | $125 (CheapOair) |
Popular in | June |
Cheapest in | August |
Average price | $378 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 19, 2026.
Use the filters below to find and compare flights from Knoxville to Mesa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvillePhoenix
TYS Knoxville McGhee Tyson - PHX Phoenix Sky Harbor Intl
TYSPHX
Knoxville McGhee Tyson
Wed 11/18
5:15 pm-11:40 pm
1 stop8h 25m
Phoenix Sky Harbor Intl
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$131
KnoxvillePhoenix
TYS Knoxville McGhee Tyson - PHX Phoenix Sky Harbor Intl
TYSPHX
Knoxville McGhee Tyson
Tue 10/27
7:16 pm-11:26 pm
1 stop7h 10m
Phoenix Sky Harbor Intl
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$131
Quickest round-trip
KnoxvillePhoenix
TYS Knoxville McGhee Tyson - PHX Phoenix Sky Harbor Intl
TYSPHX
Knoxville McGhee Tyson
Fri 10/2
6:30 am-7:31 am
Nonstop4h 01m
Phoenix Sky Harbor Intl
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$132
KnoxvillePhoenix
TYS Knoxville McGhee Tyson - PHX Phoenix Sky Harbor Intl
TYSPHX
Knoxville McGhee Tyson
Tue 10/27
6:45 am-12:37 pm
2 stops8h 52m
Phoenix Sky Harbor Intl
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$136
KnoxvillePhoenix
TYS Knoxville McGhee Tyson - PHX Phoenix Sky Harbor Intl
TYSPHX
Knoxville McGhee Tyson
Mon 11/23
5:30 am-10:21 am
1 stop6h 51m
Phoenix Sky Harbor Intl
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$149
KnoxvillePhoenix
TYS Knoxville McGhee Tyson - PHX Phoenix Sky Harbor Intl
TYSPHX
Knoxville McGhee Tyson
Mon 3/1
2:40 pm-7:05 pm
1 stop6h 25m
Phoenix Sky Harbor Intl
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$151
KnoxvillePhoenix
TYS Knoxville McGhee Tyson - PHX Phoenix Sky Harbor Intl
TYSPHX
Knoxville McGhee Tyson
Tue 10/13
7:04 pm-10:59 pm
2 stops30h 55m
Phoenix Sky Harbor Intl
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$166
KnoxvillePhoenix
TYS Knoxville McGhee Tyson - PHX Phoenix Sky Harbor Intl
TYSPHX
Knoxville McGhee Tyson
Fri 10/16
7:58 pm-11:59 pm
1 stop7h 01m
Phoenix Sky Harbor Intl
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$166
KnoxvillePhoenix
TYS Knoxville McGhee Tyson - PHX Phoenix Sky Harbor Intl
TYSPHX
Knoxville McGhee Tyson
Fri 10/23
7:25 pm-11:30 pm
2 stops7h 05m
Phoenix Sky Harbor Intl
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$171
KnoxvillePhoenix
TYS Knoxville McGhee Tyson - PHX Phoenix Sky Harbor Intl
TYSPHX
Knoxville McGhee Tyson
Thu 1/28
2:40 pm-7:35 pm
1 stop6h 55m
Phoenix Sky Harbor Intl
Tue 2/2
8:45 am-6:40 pm
2 stops7h 55m
$287
Showing 1-10 of 19 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Mesa
Have a flexible travel schedule? Discover the best time to fly to Mesa from Knoxville with our price prediction graph.
TYS-PHX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Mesa
TYS-MS9
TYS-PHX
How much does it cost to fly round-trip from Knoxville to Mesa?
Airfare is below average for this route at the moment.
Knoxville to Mesa flights typically cost between $272 and $464 in October.The cheapest round-trip price found within the last 5 days was $242 on Allegiant Air (Oct 29-Nov 1).
Reviews of airlines servicing Mesa
Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated September 19, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAllegiant Air from Knoxville to Mesa to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Boarding
8.1
Overall
7.8
Crew
8.5
Entertainment
7.8
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Boarding
8.1
Overall
7.8
Crew
8.5
Entertainment
7.8
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Boarding
8.1
Overall
7.8
Crew
8.5
Entertainment
7.8
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Boarding
8.1
Overall
7.8
Crew
8.5
Entertainment
7.8
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Boarding
8.1
Overall
7.8
Crew
8.5
Entertainment
7.8
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Boarding
8.1
Overall
7.8
Crew
8.5
Entertainment
7.8
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Knoxville and Mesa flights
Browse other Knoxville and Mesa flight options. Last updated on September 19, 2026.
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Knoxville to Mesa flights
Consider these flights traveling from Knoxville to Mesa.
Top 6 airlines flying from Knoxville to Mesa
Discover the top 6 airlines that operate flights from Knoxville to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$125 | Average$324 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$127 | Average$287 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$148 | Average$398 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$243 | Average$557 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$276 | Average$386 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$284 | Average$423 | FlexibilityNo cancel fee | On-time71% |