$96+ Cheap flights from Knoxville (TYS) to Mesa, AZ
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/6. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — PHX
Jul 13 — Jul 201
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Mesa with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Knoxville McGhee Tyson to Mesa are usually found in August or September, booked 36 days in advance, depart on a Thursday or Wednesday and return on a Wednesday
Cheap flight deals from Knoxville to Mesa
Cheapest
Best
Last-minute
One-way
Cheapest flights from Knoxville to MesaExplore the most affordable flight options available from Knoxville to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 13, 2026.
Explore the most affordable flight options available from Knoxville to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 13, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/202:39 pm
TYS
- PHX
Nonstop3h 47m
Allegiant Air
Thu 8/274:16 pm
PHX
- TYS
Nonstop3h 36m
Allegiant Air
Deal found 6/9![Allegiant Air logo]()
$161
This Cheapflightsfares deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:34 pm
TYS
- PHX
Nonstop3h 58m
Allegiant Air
Sun 9/134:22 pm
PHX
- TYS
Nonstop3h 31m
Allegiant Air
Deal found 6/9![Allegiant Air logo]()
$169
This Cheapflightsfares deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/202:39 pm
TYS
- PHX
Nonstop3h 47m
Allegiant Air
Sun 8/234:16 pm
PHX
- TYS
Nonstop3h 36m
Allegiant Air
Deal found 6/9![Allegiant Air logo]()
$195
This Cheapflightsfares deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:34 pm
TYS
- PHX
Nonstop3h 58m
Allegiant Air
Thu 9/174:22 pm
PHX
- TYS
Nonstop3h 31m
Allegiant Air
Deal found 6/9![Allegiant Air logo]()
$197
This Cheapflightsfares deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:00 am
TYS
- PHX
Nonstop4h 01m
Allegiant Air
Mon 10/199:11 am
PHX
- TYS
Nonstop3h 27m
Allegiant Air
Deal found 6/9![Allegiant Air logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:00 am
TYS
- PHX
1 stop16h 49m
Multiple Airlines
Thu 8/274:16 pm
PHX
- TYS
Nonstop3h 36m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$227
This Cheapflightsfares deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/22:41 pm
TYS
- PHX
Nonstop3h 49m
Allegiant Air
Sun 7/194:20 pm
PHX
- TYS
Nonstop3h 36m
Allegiant Air
Deal found 6/10![Allegiant Air logo]()
$233
This Mytrip deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/108:19 pm
TYS
- PHX
1 stop6h 08m
Multiple Airlines
Sun 8/164:51 pm
PHX
- TYS
Nonstop3h 36m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$234
This Cheapflightsfares deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/162:41 pm
TYS
- PHX
Nonstop3h 49m
Allegiant Air
Thu 7/234:20 pm
PHX
- TYS
Nonstop3h 36m
Allegiant Air
Deal found 6/13![Allegiant Air logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:34 pm
TYS
- PHX
Nonstop3h 58m
Multiple Airlines
Thu 9/175:55 pm
PHX
- TYS
1 stop18h 04m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$241
This Expedia deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/148:19 pm
TYS
- PHX
1 stop22h 25m
Frontier
Mon 8/178:40 am
PHX
- TYS
1 stop7h 44m
Frontier
Deal found 6/11![Frontier logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:00 am
TYS
- PHX
1 stop16h 49m
Multiple Airlines
Sun 8/304:16 pm
PHX
- TYS
Nonstop3h 36m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$249
Best flights from Knoxville to MesaDiscover carefully curated flight deals from Knoxville to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 13, 2026.
Discover carefully curated flight deals from Knoxville to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 13, 2026.
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/267:30 am
TYS
- PHX
1 stop9h 32m
Delta
Thu 12/32:15 pm
PHX
- TYS
1 stop5h 30m
Delta
Deal found 6/11![Delta logo]()
$311
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/145:45 pm
TYS
- PHX
1 stop7h 35m
Southwest
Mon 8/177:55 am
PHX
- TYS
2 stops7h 40m
Southwest
Deal found 6/11![Southwest logo]()
$343
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/264:25 pm
TYS
- PHX
2 stops10h 39m
United Airlines
Thu 12/312:55 pm
PHX
- TYS
1 stop7h 25m
United Airlines
Deal found 6/11![United Airlines logo]()
$416
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/32:47 pm
TYS
- PHX
1 stop11h 13m
Multiple Airlines
Mon 7/612:32 pm
PHX
- TYS
2 stops19h 05m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$426
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/34:20 pm
TYS
- PHX
2 stops9h 20m
Southwest
Sat 7/45:50 am
PHX
- TYS
1 stop9h 25m
Southwest
Deal found 6/12![Southwest logo]()
$404
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2210:42 am
TYS
- PHX
2 stops13h 07m
United Airlines
Sat 10/246:00 am
PHX
- TYS
2 stops12h 00m
United Airlines
Deal found 6/11![United Airlines logo]()
$421
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/38:35 am
TYS
- PHX
1 stop6h 37m
Delta
Sun 7/57:15 am
PHX
- TYS
1 stop7h 00m
Delta
Deal found 6/12![Delta logo]()
$433
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 pm
TYS
- PHX
1 stop6h 29m
United Airlines
Mon 9/146:41 pm
PHX
- TYS
2 stops12h 16m
United Airlines
Deal found 6/12![United Airlines logo]()
$430
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/34:15 pm
TYS
- PHX
1 stop6h 00m
Southwest
Fri 10/99:50 am
PHX
- TYS
2 stops8h 10m
Southwest
Deal found 6/10![Southwest logo]()
$438
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/267:55 am
TYS
- PHX
1 stop7h 33m
Delta
Sun 11/297:05 am
PHX
- TYS
1 stop8h 13m
Delta
Deal found 6/10![Delta logo]()
$443
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1610:42 am
TYS
- PHX
2 stops15h 33m
United Airlines
Mon 10/196:43 pm
PHX
- TYS
2 stops12h 54m
United Airlines
Deal found 6/12![United Airlines logo]()
$479
Last-minute flights from Knoxville to MesaDiscover last-minute flight deals from Knoxville to Mesa. Data last updated June 13, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Mesa. Data last updated June 13, 2026 and is based on user searches.
This Cheapflightsfares deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/22:41 pm
TYS
- PHX
Nonstop3h 49m
Allegiant Air
Sun 7/194:20 pm
PHX
- TYS
Nonstop3h 36m
Allegiant Air
Deal found 6/10![Allegiant Air logo]()
$233
This Mytrip deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/22:41 pm
TYS
- PHX
Nonstop3h 49m
Multiple Airlines
Thu 7/166:53 pm
PHX
- TYS
1 stop21h 31m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$289
This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/22:41 pm
TYS
- PHX
Nonstop3h 49m
Multiple Airlines
Sun 7/196:53 pm
PHX
- TYS
1 stop21h 31m
Multiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$314
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/93:44 pm
TYS
- PHX
2 stops31h 00m
Multiple Airlines
Sun 7/124:20 pm
PHX
- TYS
Nonstop3h 36m
Multiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$318
This CheapOair deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/108:19 pm
TYS
- PHX
1 stop16h 52m
Frontier
Thu 7/164:48 pm
PHX
- TYS
1 stop23h 36m
Frontier
Deal found 6/10![Frontier logo]()
$270
This Cheapflightsfares deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/162:41 pm
TYS
- PHX
Nonstop3h 49m
Allegiant Air
Thu 7/234:20 pm
PHX
- TYS
Nonstop3h 36m
Allegiant Air
Deal found 6/13![Allegiant Air logo]()
$237
This Expedia deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/178:19 pm
TYS
- PHX
1 stop25h 28m
Frontier
Mon 7/206:40 am
PHX
- TYS
1 stop9h 44m
Frontier
Deal found 6/10![Frontier logo]()
$260
This Cheapflightsfares deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/262:41 pm
TYS
- PHX
Nonstop3h 49m
Allegiant Air
Sun 8/24:20 pm
PHX
- TYS
Nonstop3h 36m
Allegiant Air
Deal found 6/9![Allegiant Air logo]()
$268
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/267:00 am
TYS
- PHX
1 stop27h 40m
Multiple Airlines
Sun 8/24:20 pm
PHX
- TYS
Nonstop3h 36m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$317
One-way flights from Knoxville to MesaSearch for one-way flight options from Knoxville to Mesa. Find affordable one-way fares based on user searches. Data last updated June 13, 2026.
Search for one-way flight options from Knoxville to Mesa. Find affordable one-way fares based on user searches. Data last updated June 13, 2026.
This CheapOair deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/62:34 pm
TYS
- PHX
Nonstop3h 58m
Allegiant Air
Deal found 6/10![Allegiant Air logo]()
$96
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/63:01 pm
TYS
- PHX
Nonstop4h 10m
Allegiant Air
Deal found 6/13![Allegiant Air logo]()
$105
This Priceline deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/108:19 pm
TYS
- PHX
1 stop6h 08m
Frontier
Deal found 6/10![Frontier logo]()
$120
This CheapOair deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/121:39 pm
TYS
- PHX
Nonstop4h 01m
Allegiant Air
Deal found 6/10![Allegiant Air logo]()
$123
This Frontier deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/138:19 pm
TYS
- PHX
1 stop6h 13m
Frontier
Deal found 6/9![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/35:32 pm
TYS
- PHX
1 stop22h 02m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$133
This Expedia deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/108:19 pm
TYS
- PHX
1 stop16h 52m
Frontier
Deal found 6/10![Frontier logo]()
$139
Find flight deals from Knoxville to Mesa
Keep the following information in mind while searching for Knoxville to Mesa flight deals. Data was last updated June 13, 2026.
Round-trip from | $161 (Cheapflightsfares) |
|---|---|
One-way from | $96 (CheapOair) |
Popular in | June |
Cheapest in | August |
Average price | $530 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 13, 2026.
Use the filters below to find and compare flights from Knoxville to Mesa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvillePhoenix
TYS - PHX
TYSPHX
Knoxville McGhee Tyson
Thu 11/26
7:30 am-3:02 pm
1 stop9h 32m
Phoenix Sky Harbor Intl
Thu 12/3
2:15 pm-9:45 pm
1 stop5h 30m
$311
KnoxvillePhoenix
TYS - PHX
TYSPHX
Knoxville McGhee Tyson
Fri 8/14
5:45 pm-10:20 pm
1 stop7h 35m
Phoenix Sky Harbor Intl
Mon 8/17
7:55 am-6:35 pm
2 stops7h 40m
$343
KnoxvillePhoenix
TYS - PHX
TYSPHX
Knoxville McGhee Tyson
Fri 7/3
4:20 pm-10:40 pm
2 stops9h 20m
Phoenix Sky Harbor Intl
Sat 7/4
5:50 am-6:15 pm
1 stop9h 25m
$404
KnoxvillePhoenix
TYS - PHX
TYSPHX
Knoxville McGhee Tyson
Thu 11/26
4:25 pm-1:04 am
2 stops10h 39m
Phoenix Sky Harbor Intl
Thu 12/3
12:55 pm-10:20 pm
1 stop7h 25m
$416
KnoxvillePhoenix
TYS - PHX
TYSPHX
Knoxville McGhee Tyson
Thu 10/22
10:42 am-8:49 pm
2 stops13h 07m
Phoenix Sky Harbor Intl
Sat 10/24
6:00 am-9:00 pm
2 stops12h 00m
$421
KnoxvillePhoenix
TYS - PHX
TYSPHX
Knoxville McGhee Tyson
Fri 7/3
2:47 pm-11:00 pm
1 stop11h 13m
Phoenix Sky Harbor Intl
Mon 7/6
12:32 pm-10:37 am
2 stops19h 05m
$426
KnoxvillePhoenix
TYS - PHX
TYSPHX
Knoxville McGhee Tyson
Wed 9/9
6:00 pm-9:29 pm
1 stop6h 29m
Phoenix Sky Harbor Intl
Mon 9/14
6:41 pm-9:57 am
2 stops12h 16m
$430
Quickest round-trip
KnoxvillePhoenix
TYS - PHX
TYSPHX
Knoxville McGhee Tyson
Fri 7/3
8:35 am-12:12 pm
1 stop6h 37m
Phoenix Sky Harbor Intl
Sun 7/5
7:15 am-5:15 pm
1 stop7h 00m
$433
KnoxvillePhoenix
TYS - PHX
TYSPHX
Knoxville McGhee Tyson
Sat 10/3
4:15 pm-7:15 pm
1 stop6h 00m
Phoenix Sky Harbor Intl
Fri 10/9
9:50 am-9:00 pm
2 stops8h 10m
$438
KnoxvillePhoenix
TYS - PHX
TYSPHX
Knoxville McGhee Tyson
Thu 11/26
7:55 am-1:28 pm
1 stop7h 33m
Phoenix Sky Harbor Intl
Sun 11/29
7:05 am-5:18 pm
1 stop8h 13m
$443
Showing 1-10 of 19 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Mesa
Have a flexible travel schedule? Discover the best time to fly to Mesa from Knoxville with our price prediction graph.
TYS-PHX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Mesa
TYS-MS9
TYS-PHX
How much does it cost to fly round-trip from Knoxville to Mesa?
Reviews of airlines servicing Mesa
Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated June 13, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAllegiant Air from Knoxville to Mesa to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Crew
8.5
Food
7.2
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Crew
8.5
Food
7.2
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Crew
8.5
Food
7.2
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Crew
8.5
Food
7.2
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Crew
8.5
Food
7.2
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Crew
8.5
Food
7.2
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
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Knoxville and Mesa flights
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| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$118 | Average$264 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$125 | Average$327 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$128 | Average$396 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$229 | Average$457 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$268 | Average$409 | FlexibilityNo cancel fee | On-time71% |