$77+ Cheap flights from Knoxville (TYS) to Mesa, AZ
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/20. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — PHX
Aug 1 — Aug 81
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Mesa with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Knoxville McGhee Tyson to Mesa are usually found in August or September, booked 36 days in advance, depart on a Thursday or Wednesday and return on a Wednesday
Cheap flight deals from Knoxville to Mesa
Cheapest
Best
Last-minute
One-way
Cheapest flights from Knoxville to MesaExplore the most affordable flight options available from Knoxville to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2026.
Explore the most affordable flight options available from Knoxville to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2026.
This CheapOair deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/202:39 pm
TYS
- PHX
Nonstop3h 47m
Allegiant Air
Sun 8/234:16 pm
PHX
- TYS
Nonstop3h 36m
Allegiant Air
Deal found 6/28![Allegiant Air logo]()
$136
This CheapOair deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/232:39 pm
TYS
- PHX
Nonstop3h 47m
Allegiant Air
Thu 8/274:16 pm
PHX
- TYS
Nonstop3h 36m
Allegiant Air
Deal found 6/29![Allegiant Air logo]()
$137
This Cheapflightsfares deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/32:34 pm
TYS
- PHX
Nonstop3h 58m
Allegiant Air
Sun 9/64:22 pm
PHX
- TYS
Nonstop3h 31m
Allegiant Air
Deal found 6/27![Allegiant Air logo]()
$153
This Cheapflightsfares deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:34 pm
TYS
- PHX
Nonstop3h 58m
Allegiant Air
Sun 9/134:22 pm
PHX
- TYS
Nonstop3h 31m
Allegiant Air
Deal found 7/2![Allegiant Air logo]()
$161
This CheapOair deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/92:51 pm
TYS
- PHX
Nonstop4h 10m
Allegiant Air
Thu 8/135:01 pm
PHX
- TYS
Nonstop3h 36m
Allegiant Air
Deal found 6/28![Allegiant Air logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/97:00 am
TYS
- PHX
1 stop27h 40m
Multiple Airlines
Thu 8/135:01 pm
PHX
- TYS
Nonstop3h 36m
Multiple Airlines
Deal found 6/28![Multiple Airlines logo]()
$215
This Cheapflightsfares deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:00 am
TYS
- PHX
Nonstop4h 01m
Allegiant Air
Mon 10/129:11 am
PHX
- TYS
Nonstop3h 27m
Allegiant Air
Deal found 6/27![Allegiant Air logo]()
$221
This Kiwi.com deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/237:00 am
TYS
- PHX
1 stop27h 40m
Multiple Airlines
Thu 8/274:16 pm
PHX
- TYS
Nonstop3h 36m
Multiple Airlines
Deal found 6/29![Multiple Airlines logo]()
$222
This Cheapflightsfares deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/262:41 pm
TYS
- PHX
Nonstop3h 49m
Allegiant Air
Sun 8/24:20 pm
PHX
- TYS
Nonstop3h 36m
Allegiant Air
Deal found 6/30![Allegiant Air logo]()
$229
Best flights from Knoxville to MesaDiscover carefully curated flight deals from Knoxville to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 2, 2026.
Discover carefully curated flight deals from Knoxville to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 2, 2026.
This Delta deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:18 pm
TYS
- PHX
1 stop7h 39m
Delta
Tue 10/276:00 am
PHX
- TYS
1 stop9h 16m
Delta
Deal found 6/29![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:10 am
TYS
- PHX
2 stops8h 50m
Southwest
Sat 8/296:15 am
PHX
- TYS
2 stops8h 25m
Southwest
Deal found 6/27![Southwest logo]()
$334
This CheapOair deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/228:19 pm
TYS
- PHX
1 stop28h 09m
Frontier
Fri 7/246:40 am
PHX
- TYS
1 stop9h 44m
Frontier
Deal found 6/27![Frontier logo]()
$340
This United Airlines deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/94:50 pm
TYS
- PHX
1 stop6h 34m
United Airlines
Mon 9/146:41 pm
PHX
- TYS
2 stops12h 16m
United Airlines
Deal found 6/28![United Airlines logo]()
$414
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/122:30 pm
TYS
- PHX
1 stop6h 06m
Delta
Fri 11/1311:00 am
PHX
- TYS
1 stop7h 40m
Delta
Deal found 7/1![Delta logo]()
$369
This Southwest deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:10 am
TYS
- PHX
2 stops8h 30m
Southwest
Sun 8/239:50 am
PHX
- TYS
2 stops8h 55m
Southwest
Deal found 6/28![Southwest logo]()
$379
This United Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2210:42 am
TYS
- PHX
2 stops13h 07m
United Airlines
Tue 10/2711:25 am
PHX
- TYS
1 stop6h 19m
United Airlines
Deal found 6/29![United Airlines logo]()
$414
This Southwest deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/35:45 pm
TYS
- PHX
2 stops7h 10m
Southwest
Sun 9/68:20 pm
PHX
- TYS
2 stops13h 00m
Southwest
Deal found 6/27![Southwest logo]()
$385
Last-minute flights from Knoxville to MesaDiscover last-minute flight deals from Knoxville to Mesa. Data last updated July 2, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Mesa. Data last updated July 2, 2026 and is based on user searches.
This Cheapflightsfares deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/262:41 pm
TYS
- PHX
Nonstop3h 49m
Allegiant Air
Sun 8/24:20 pm
PHX
- TYS
Nonstop3h 36m
Allegiant Air
Deal found 6/30![Allegiant Air logo]()
$229
This CheapOair deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/92:51 pm
TYS
- PHX
Nonstop4h 10m
Allegiant Air
Thu 8/135:01 pm
PHX
- TYS
Nonstop3h 36m
Allegiant Air
Deal found 6/28![Allegiant Air logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/97:00 am
TYS
- PHX
1 stop27h 40m
Multiple Airlines
Thu 8/135:01 pm
PHX
- TYS
Nonstop3h 36m
Multiple Airlines
Deal found 6/28![Multiple Airlines logo]()
$215
This CheapOair deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/202:39 pm
TYS
- PHX
Nonstop3h 47m
Allegiant Air
Sun 8/234:16 pm
PHX
- TYS
Nonstop3h 36m
Allegiant Air
Deal found 6/28![Allegiant Air logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:00 am
TYS
- PHX
1 stop17h 28m
Multiple Airlines
Sun 8/234:16 pm
PHX
- TYS
Nonstop3h 36m
Multiple Airlines
Deal found 6/28![Multiple Airlines logo]()
$233
This CheapOair deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/232:39 pm
TYS
- PHX
Nonstop3h 47m
Allegiant Air
Thu 8/274:16 pm
PHX
- TYS
Nonstop3h 36m
Allegiant Air
Deal found 6/29![Allegiant Air logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/237:00 am
TYS
- PHX
1 stop27h 40m
Multiple Airlines
Thu 8/274:16 pm
PHX
- TYS
Nonstop3h 36m
Multiple Airlines
Deal found 6/29![Multiple Airlines logo]()
$222
One-way flights from Knoxville to MesaSearch for one-way flight options from Knoxville to Mesa. Find affordable one-way fares based on user searches. Data last updated July 2, 2026.
Search for one-way flight options from Knoxville to Mesa. Find affordable one-way fares based on user searches. Data last updated July 2, 2026.
This CheapOair deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/202:39 pm
TYS
- PHX
Nonstop3h 47m
Allegiant Air
Deal found 6/27![Allegiant Air logo]()
$77
This Cheapflightsfares deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:00 am
TYS
- PHX
Nonstop4h 01m
Allegiant Air
Deal found 6/30![Allegiant Air logo]()
$98
This Cheapflightsfares deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/272:39 pm
TYS
- PHX
Nonstop3h 47m
Allegiant Air
Deal found 7/1![Allegiant Air logo]()
$107
This CheapOair deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/62:34 pm
TYS
- PHX
Nonstop3h 58m
Allegiant Air
Deal found 6/28![Allegiant Air logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/137:00 am
TYS
- PHX
1 stop27h 58m
Multiple Airlines
Deal found 7/1![Multiple Airlines logo]()
$127
This Priceline deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/38:19 pm
TYS
- PHX
1 stop6h 13m
Frontier
Deal found 6/28![Frontier logo]()
$130
This Cheapflightsfares deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/132:34 pm
TYS
- PHX
Nonstop3h 58m
Allegiant Air
Deal found 7/1![Allegiant Air logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/22:41 pm
TYS
- PHX
Nonstop3h 49m
Allegiant Air
Deal found 6/28![Allegiant Air logo]()
$137
This CheapOair deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/121:39 pm
TYS
- PHX
Nonstop4h 01m
Allegiant Air
Deal found 6/27![Allegiant Air logo]()
$140
Find flight deals from Knoxville to Mesa
Keep the following information in mind while searching for Knoxville to Mesa flight deals. Data was last updated July 2, 2026.
Round-trip from | $136 (CheapOair) |
|---|---|
One-way from | $77 (CheapOair) |
Popular in | June |
Cheapest in | August |
Average price | $353 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 2, 2026.
Use the filters below to find and compare flights from Knoxville to Mesa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvillePhoenix
TYS - PHX
TYSPHX
Knoxville McGhee Tyson
Thu 10/22
5:18 pm-9:57 pm
1 stop7h 39m
Phoenix Sky Harbor Intl
Tue 10/27
6:00 am-6:16 pm
1 stop9h 16m
$309
KnoxvillePhoenix
TYS - PHX
TYSPHX
Knoxville McGhee Tyson
Thu 8/20
7:10 am-1:00 pm
2 stops8h 50m
Phoenix Sky Harbor Intl
Sat 8/29
6:15 am-5:40 pm
2 stops8h 25m
$334
KnoxvillePhoenix
TYS - PHX
TYSPHX
Knoxville McGhee Tyson
Wed 7/22
8:19 pm-9:28 pm
1 stop28h 09m
Phoenix Sky Harbor Intl
Fri 7/24
6:40 am-7:24 pm
1 stop9h 44m
$340
Quickest round-trip
KnoxvillePhoenix
TYS - PHX
TYSPHX
Knoxville McGhee Tyson
Thu 11/12
2:30 pm-6:36 pm
1 stop6h 06m
Phoenix Sky Harbor Intl
Fri 11/13
11:00 am-8:40 pm
1 stop7h 40m
$369
KnoxvillePhoenix
TYS - PHX
TYSPHX
Knoxville McGhee Tyson
Thu 8/20
7:10 am-12:40 pm
2 stops8h 30m
Phoenix Sky Harbor Intl
Sun 8/23
9:50 am-9:45 pm
2 stops8h 55m
$379
KnoxvillePhoenix
TYS - PHX
TYSPHX
Knoxville McGhee Tyson
Thu 9/3
5:45 pm-9:55 pm
2 stops7h 10m
Phoenix Sky Harbor Intl
Sun 9/6
8:20 pm-12:20 pm
2 stops13h 00m
$385
KnoxvillePhoenix
TYS - PHX
TYSPHX
Knoxville McGhee Tyson
Wed 9/9
4:50 pm-8:24 pm
1 stop6h 34m
Phoenix Sky Harbor Intl
Mon 9/14
6:41 pm-9:57 am
2 stops12h 16m
$414
KnoxvillePhoenix
TYS - PHX
TYSPHX
Knoxville McGhee Tyson
Thu 10/22
10:42 am-8:49 pm
2 stops13h 07m
Phoenix Sky Harbor Intl
Tue 10/27
11:25 am-8:44 pm
1 stop6h 19m
$414
Cheapest one-way
Quickest one-way
KnoxvillePhoenix
TYS - PHX
TYSPHX
Knoxville McGhee Tyson
Thu 11/12
1:39 pm-3:40 pm
Nonstop4h 01m
$140
KnoxvillePhoenix
TYS - PHX
TYSPHX
Knoxville McGhee Tyson
Thu 8/20
5:15 am-9:40 am
1 stop7h 25m
$155
Showing 1-10 of 16 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Mesa
Have a flexible travel schedule? Discover the best time to fly to Mesa from Knoxville with our price prediction graph.
TYS-PHX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Mesa
TYS-MS9
TYS-PHX
How much does it cost to fly round-trip from Knoxville to Mesa?
Reviews of airlines servicing Mesa
Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated July 2, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAllegiant Air from Knoxville to Mesa to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.8
Food
7.2
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.8
Food
7.2
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.8
Food
7.2
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.8
Food
7.2
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.8
Food
7.2
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.8
Food
7.2
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Knoxville and Mesa flights
Browse other Knoxville and Mesa flight options. Last updated on July 2, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on July 2, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Knoxville to Mesa flights
Consider these flights traveling from Knoxville to Mesa.
Top 6 airlines flying from Knoxville to Mesa
Discover the top 6 airlines that operate flights from Knoxville to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$118 | Average$269 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$125 | Average$327 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$128 | Average$409 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$229 | Average$522 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$268 | Average$408 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$276 | Average$472 | FlexibilityNo cancel fee | On-time63% |