$121+ Cheap flights from Knoxville (TYS) to Mesa, AZ
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/19. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — PHX
Oct 21 — Oct 281
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Mesa with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Knoxville McGhee Tyson to Mesa are usually found in August or January, booked 36 days in advance, depart on a Friday or Wednesday and return on a Wednesday
Cheap flight deals from Knoxville to Mesa
Cheapest
Best
Last-minute
One-way
Cheapest flights from Knoxville to MesaExplore the most affordable flight options available from Knoxville to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 21, 2026.
Explore the most affordable flight options available from Knoxville to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:42 pm -
1 stop22h 44m
Thu 10/297:30 am -
1 stop10h 09m
Deal found 9/19![Multiple Airlines logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:30 am -
1 stop20h 12m
Sun 11/153:20 pm -
Nonstop3h 36m
Deal found 9/17![Multiple Airlines logo]()
$251
This Cheapflightsfares deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/121:39 pm -
Nonstop4h 01m
Sun 11/153:20 pm -
Nonstop3h 36m
Deal found 9/20![Allegiant Air logo]()
$258
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:40 am -
1 stop6h 29m
Wed 10/287:05 am -
1 stop6h 22m
Deal found 9/16![Delta logo]()
$261
This Cheapflightsfares deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:30 am -
Nonstop4h 01m
Mon 10/199:11 am -
Nonstop3h 27m
Deal found 9/20![Allegiant Air logo]()
$264
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:20 pm -
1 stop7h 30m
Wed 10/2810:05 am -
2 stops8h 00m
Deal found 9/16![Southwest logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:30 am -
1 stop28h 34m
Sun 11/153:20 pm -
Nonstop3h 36m
Deal found 9/18![Multiple Airlines logo]()
$278
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:25 pm -
1 stop7h 50m
Sat 12/57:05 am -
1 stop7h 05m
Deal found 9/17![Southwest logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/138:35 am -
3 stops31h 10m
Sun 11/153:20 pm -
Nonstop3h 36m
Deal found 9/17![Multiple Airlines logo]()
$282
Best flights from Knoxville to MesaDiscover carefully curated flight deals from Knoxville to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 21, 2026.
Discover carefully curated flight deals from Knoxville to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 21, 2026.
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:23 pm -
1 stop6h 58m
Mon 11/211:25 pm -
1 stop8h 55m
Deal found 9/17![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:45 am -
2 stops8h 52m
Wed 11/182:50 pm -
1 stop5h 42m
Deal found 9/20![United Airlines logo]()
$324
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:15 am -
2 stops7h 35m
Wed 10/2810:05 am -
2 stops8h 00m
Deal found 9/16![Southwest logo]()
$361
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/93:40 pm -
2 stops8h 25m
Thu 11/1211:25 am -
2 stops8h 20m
Deal found 9/16![Southwest logo]()
$381
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2310:42 am -
1 stop9h 53m
Mon 11/27:37 pm -
2 stops12h 16m
Deal found 9/17![United Airlines logo]()
$424
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/267:25 pm -
2 stops7h 05m
Thu 10/2912:20 pm -
2 stops7h 25m
Deal found 9/19![Southwest logo]()
$427
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2210:42 am -
1 stop8h 01m
Sat 10/248:00 am -
2 stops10h 01m
Deal found 9/19![United Airlines logo]()
$464
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1610:42 am -
2 stops15h 33m
Fri 10/236:43 pm -
2 stops12h 54m
Deal found 9/16![United Airlines logo]()
$465
This Southwest deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:25 pm -
2 stops7h 05m
Mon 10/2611:40 am -
2 stops8h 05m
Deal found 9/18![Southwest logo]()
$474
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:45 am -
2 stops8h 52m
Sun 11/11:00 pm -
1 stop7h 32m
Deal found 9/17![United Airlines logo]()
$480
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/129:00 am -
2 stops14h 25m
Sun 11/1511:59 pm -
1 stop9h 31m
Deal found 9/20![United Airlines logo]()
$489
Last-minute flights from Knoxville to MesaDiscover last-minute flight deals from Knoxville to Mesa. Data last updated September 21, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Mesa. Data last updated September 21, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/242:34 pm -
Nonstop3h 58m
Sat 10/33:38 pm -
Nonstop3h 27m
Deal found 9/17![Allegiant Air logo]()
$284
This Cheapflightsfares deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:30 am -
Nonstop4h 01m
Mon 10/199:11 am -
Nonstop3h 27m
Deal found 9/20![Allegiant Air logo]()
$264
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/74:49 pm -
1 stop8h 10m
Tue 10/1310:10 pm -
1 stop7h 22m
Deal found 9/17![American Airlines logo]()
$291
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1610:03 pm -
1 stop23h 30m
Mon 10/199:11 am -
Nonstop3h 27m
Deal found 9/19![Multiple Airlines logo]()
$278
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:40 am -
1 stop6h 29m
Wed 10/287:05 am -
1 stop6h 22m
Deal found 9/16![Delta logo]()
$261
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:20 pm -
1 stop7h 30m
Wed 10/2810:05 am -
2 stops8h 00m
Deal found 9/16![Southwest logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/259:29 pm -
1 stop17h 48m
Sun 11/14:43 pm -
Nonstop3h 27m
Deal found 9/17![Multiple Airlines logo]()
$295
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:42 pm -
1 stop22h 44m
Thu 10/297:30 am -
1 stop10h 09m
Deal found 9/19![Multiple Airlines logo]()
$243
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:25 pm -
1 stop7h 50m
Sat 12/57:05 am -
1 stop7h 05m
Deal found 9/17![Southwest logo]()
$279
One-way flights from Knoxville to MesaSearch for one-way flight options from Knoxville to Mesa. Find affordable one-way fares based on user searches. Data last updated September 21, 2026.
Search for one-way flight options from Knoxville to Mesa. Find affordable one-way fares based on user searches. Data last updated September 21, 2026.
This Trip.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/199:59 pm -
1 stop25h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Multiple Airlines logo]()
$121
This CheapOair deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:30 am -
Nonstop4h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Allegiant Air logo]()
$125
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:15 pm -
1 stop8h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Southwest logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:30 am -
1 stop20h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Multiple Airlines logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1512:29 pm -
Nonstop4h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Allegiant Air logo]()
$145
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:16 pm -
1 stop7h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Delta logo]()
$146
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:45 am -
2 stops8h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![United Airlines logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:30 am -
1 stop28h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Multiple Airlines logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:30 am -
1 stop28h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Multiple Airlines logo]()
$153
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:26 pm -
1 stop7h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![American Airlines logo]()
$160
Find flight deals from Knoxville to Mesa
Keep the following information in mind while searching for Knoxville to Mesa flight deals. Data was last updated September 21, 2026.
Round-trip from | $243 (Kiwi.com) |
|---|---|
One-way from | $121 (Trip.com) |
Popular in | June |
Cheapest in | August |
Average price | $378 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 21, 2026.
Use the filters below to find and compare flights from Knoxville to Mesa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvillePhoenix
TYS Knoxville McGhee Tyson - PHX Phoenix Sky Harbor Intl
TYSPHX
Knoxville McGhee Tyson
Wed 11/18
5:15 pm-11:40 pm
1 stop8h 25m
Phoenix Sky Harbor Intl
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$131
Quickest round-trip
KnoxvillePhoenix
TYS Knoxville McGhee Tyson - PHX Phoenix Sky Harbor Intl
TYSPHX
Knoxville McGhee Tyson
Sun 11/15
12:29 pm-2:30 pm
Nonstop4h 01m
Phoenix Sky Harbor Intl
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$145
KnoxvillePhoenix
TYS Knoxville McGhee Tyson - PHX Phoenix Sky Harbor Intl
TYSPHX
Knoxville McGhee Tyson
Mon 3/1
2:40 pm-7:05 pm
1 stop6h 25m
Phoenix Sky Harbor Intl
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$151
KnoxvillePhoenix
TYS Knoxville McGhee Tyson - PHX Phoenix Sky Harbor Intl
TYSPHX
Knoxville McGhee Tyson
Sun 11/8
6:30 am-9:04 am
1 stop28h 34m
Phoenix Sky Harbor Intl
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$153
KnoxvillePhoenix
TYS Knoxville McGhee Tyson - PHX Phoenix Sky Harbor Intl
TYSPHX
Knoxville McGhee Tyson
Sat 10/17
4:16 pm-10:41 pm
1 stop9h 25m
Phoenix Sky Harbor Intl
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$160
KnoxvillePhoenix
TYS Knoxville McGhee Tyson - PHX Phoenix Sky Harbor Intl
TYSPHX
Knoxville McGhee Tyson
Tue 10/13
7:04 pm-10:59 pm
2 stops30h 55m
Phoenix Sky Harbor Intl
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$166
KnoxvillePhoenix
TYS Knoxville McGhee Tyson - PHX Phoenix Sky Harbor Intl
TYSPHX
Knoxville McGhee Tyson
Tue 10/27
10:45 am-6:55 pm
2 stops11h 10m
Phoenix Sky Harbor Intl
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$186
KnoxvillePhoenix
TYS Knoxville McGhee Tyson - PHX Phoenix Sky Harbor Intl
TYSPHX
Knoxville McGhee Tyson
Fri 10/23
6:23 pm-10:21 pm
1 stop6h 58m
Phoenix Sky Harbor Intl
Mon 11/2
11:25 pm-10:20 am
1 stop8h 55m
$319
KnoxvillePhoenix
TYS Knoxville McGhee Tyson - PHX Phoenix Sky Harbor Intl
TYSPHX
Knoxville McGhee Tyson
Sat 11/14
6:45 am-1:37 pm
2 stops8h 52m
Phoenix Sky Harbor Intl
Wed 11/18
2:50 pm-10:32 pm
1 stop5h 42m
$324
KnoxvillePhoenix
TYS Knoxville McGhee Tyson - PHX Phoenix Sky Harbor Intl
TYSPHX
Knoxville McGhee Tyson
Wed 10/21
7:15 am-11:50 am
2 stops7h 35m
Phoenix Sky Harbor Intl
Wed 10/28
10:05 am-9:05 pm
2 stops8h 00m
$361
Showing 1-10 of 18 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Mesa
Have a flexible travel schedule? Discover the best time to fly to Mesa from Knoxville with our price prediction graph.
TYS-PHX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Mesa
TYS-MS9
TYS-PHX
How much does it cost to fly round-trip from Knoxville to Mesa?
Airfare is below average for this route at the moment.
Knoxville to Mesa flights typically cost between $272 and $464 in October.The cheapest round-trip price found within the last 5 days was $243 on Multiple Airlines (Oct 26-Oct 29).
Reviews of airlines servicing Mesa
Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated September 21, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAllegiant Air from Knoxville to Mesa to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Crew
8.5
Entertainment
7.8
Boarding
8.1
Food
7.2
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Comfort
7.8
Crew
8.5
Entertainment
7.8
Boarding
8.1
Food
7.2
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Comfort
7.8
Crew
8.5
Entertainment
7.8
Boarding
8.1
Food
7.2
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Comfort
7.8
Crew
8.5
Entertainment
7.8
Boarding
8.1
Food
7.2
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Comfort
7.8
Crew
8.5
Entertainment
7.8
Boarding
8.1
Food
7.2
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Comfort
7.8
Crew
8.5
Entertainment
7.8
Boarding
8.1
Food
7.2
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Find flights from Knoxville to Mesa, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Knoxville and Mesa flights
Browse other Knoxville and Mesa flight options. Last updated on September 21, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on September 21, 2026.
Popular flight searches
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Knoxville to Mesa flights
Consider these flights traveling from Knoxville to Mesa.
Top 6 airlines flying from Knoxville to Mesa
Discover the top 6 airlines that operate flights from Knoxville to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$125 | Average$324 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$127 | Average$287 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$148 | Average$396 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$243 | Average$557 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$276 | Average$386 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$284 | Average$422 | FlexibilityNo cancel fee | On-time71% |