$80+ Cheap flights from Knoxville (TYS) to Mesa, AZ
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/30. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — PHX
May 18 — May 251
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Mesa with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Knoxville McGhee Tyson to Mesa are usually found in September or August, booked 66 days in advance, depart on a Friday or Thursday and return on a Wednesday
Cheap flight deals from Knoxville to Mesa
Cheapest
Best
Last-minute
One-way
Cheapest flights from Knoxville to MesaExplore the most affordable flight options available from Knoxville to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 18, 2026.
Explore the most affordable flight options available from Knoxville to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 18, 2026.
This Trip.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/308:00 am
TYS
- PHX
Nonstop4h 06m
Multiple Airlines
Thu 5/74:17 pm
PHX
- TYS
1 stop24h 16m
Multiple Airlines
Deal found 4/16![Multiple Airlines logo]()
$172
This Vliegwinkel deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Vliegwinkel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/304:28 pm
TYS
- PHX
1 stop18h 08m
Frontier
Thu 5/74:17 pm
PHX
- TYS
1 stop24h 16m
Frontier
Deal found 4/16![Frontier logo]()
$194
This Cheapflightsfares deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:00 am
TYS
- PHX
Nonstop4h 01m
Allegiant Air
Thu 10/223:43 pm
PHX
- TYS
Nonstop3h 27m
Allegiant Air
Deal found 4/16![Allegiant Air logo]()
$213
This Booking.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/148:00 am
TYS
- PHX
Nonstop4h 06m
Allegiant Air
Sun 5/179:56 am
PHX
- TYS
Nonstop3h 24m
Allegiant Air
Deal found 4/13![Allegiant Air logo]()
$214
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/172:34 pm
TYS
- PHX
Nonstop3h 58m
Allegiant Air
Sun 9/204:22 pm
PHX
- TYS
Nonstop3h 31m
Allegiant Air
Deal found 4/16![Allegiant Air logo]()
$228
This CheapOair deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/264:28 pm
TYS
- PHX
1 stop18h 08m
Frontier
Sat 5/29:24 pm
PHX
- TYS
1 stop15h 09m
Frontier
Deal found 4/13![Frontier logo]()
$236
This Trip.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/268:00 am
TYS
- PHX
Nonstop4h 06m
Multiple Airlines
Sun 5/36:50 am
PHX
- TYS
1 stop5h 43m
Multiple Airlines
Deal found 4/15![Multiple Airlines logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1411:27 am
TYS
- PHX
2 stops36h 06m
Multiple Airlines
Sun 5/179:56 am
PHX
- TYS
Nonstop3h 24m
Multiple Airlines
Deal found 4/15![Multiple Airlines logo]()
$239
This CheapOair deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/118:32 pm
TYS
- PHX
1 stop21h 51m
Frontier
Fri 5/155:15 am
PHX
- TYS
1 stop11h 18m
Frontier
Deal found 4/15![Frontier logo]()
$241
Best flights from Knoxville to MesaDiscover carefully curated flight deals from Knoxville to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 18, 2026.
Discover carefully curated flight deals from Knoxville to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 18, 2026.
This Southwest deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:50 pm
TYS
- PHX
1 stop7h 40m
Southwest
Sat 5/307:00 am
PHX
- TYS
2 stops8h 30m
Southwest
Deal found 4/14![Southwest logo]()
$372
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/188:32 pm
TYS
- PHX
1 stop16h 33m
Multiple Airlines
Thu 5/211:05 pm
PHX
- TYS
2 stops31h 32m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$392
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:30 am
TYS
- PHX
1 stop7h 31m
United Airlines
Sat 9/191:31 pm
PHX
- TYS
1 stop6h 07m
United Airlines
Deal found 4/17![United Airlines logo]()
$399
This CheapOair deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/188:32 pm
TYS
- PHX
1 stop16h 33m
Frontier
Thu 5/214:17 pm
PHX
- TYS
1 stop24h 07m
Frontier
Deal found 4/17![Frontier logo]()
$422
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:50 am
TYS
- PHX
2 stops9h 30m
Southwest
Sat 9/196:00 am
PHX
- TYS
1 stop10h 20m
Southwest
Deal found 4/17![Southwest logo]()
$439
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:01 pm
TYS
- PHX
1 stop7h 00m
United Airlines
Mon 5/1111:30 pm
PHX
- TYS
1 stop7h 36m
United Airlines
Deal found 4/15![United Airlines logo]()
$467
This Southwest deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/54:00 pm
TYS
- PHX
1 stop9h 00m
Southwest
Fri 10/911:50 pm
PHX
- TYS
1 stop9h 05m
Southwest
Deal found 4/12![Southwest logo]()
$439
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/142:45 pm
TYS
- PHX
2 stops10h 20m
Southwest
Tue 5/198:55 am
PHX
- TYS
2 stops7h 45m
Southwest
Deal found 4/17![Southwest logo]()
$451
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/138:15 am
TYS
- PHX
2 stops10h 00m
Southwest
Wed 5/208:10 am
PHX
- TYS
2 stops8h 30m
Southwest
Deal found 4/15![Southwest logo]()
$464
Last-minute flights from Knoxville to MesaDiscover last-minute flight deals from Knoxville to Mesa. Data last updated April 18, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Mesa. Data last updated April 18, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/264:28 pm
TYS
- PHX
1 stop18h 08m
Frontier
Sat 5/29:24 pm
PHX
- TYS
1 stop15h 09m
Frontier
Deal found 4/13![Frontier logo]()
$236
This Trip.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/268:00 am
TYS
- PHX
Nonstop4h 06m
Multiple Airlines
Sun 5/36:50 am
PHX
- TYS
1 stop5h 43m
Multiple Airlines
Deal found 4/15![Multiple Airlines logo]()
$237
This Priceline deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/264:28 pm
TYS
- PHX
1 stop6h 42m
Frontier
Sun 5/36:50 am
PHX
- TYS
1 stop5h 43m
Frontier
Deal found 4/15![Frontier logo]()
$251
This Trip.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/308:00 am
TYS
- PHX
Nonstop4h 06m
Multiple Airlines
Thu 5/74:17 pm
PHX
- TYS
1 stop24h 16m
Multiple Airlines
Deal found 4/16![Multiple Airlines logo]()
$172
This Vliegwinkel deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Vliegwinkel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/304:28 pm
TYS
- PHX
1 stop18h 08m
Frontier
Thu 5/74:17 pm
PHX
- TYS
1 stop24h 16m
Frontier
Deal found 4/16![Frontier logo]()
$194
This CheapOair deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/118:32 pm
TYS
- PHX
1 stop21h 51m
Frontier
Fri 5/155:15 am
PHX
- TYS
1 stop11h 18m
Frontier
Deal found 4/15![Frontier logo]()
$241
This Booking.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/148:00 am
TYS
- PHX
Nonstop4h 06m
Allegiant Air
Sun 5/179:56 am
PHX
- TYS
Nonstop3h 24m
Allegiant Air
Deal found 4/13![Allegiant Air logo]()
$214
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1411:27 am
TYS
- PHX
2 stops36h 06m
Multiple Airlines
Sun 5/179:56 am
PHX
- TYS
Nonstop3h 24m
Multiple Airlines
Deal found 4/15![Multiple Airlines logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/282:49 pm
TYS
- PHX
Nonstop4h 10m
Multiple Airlines
Wed 6/36:51 pm
PHX
- TYS
2 stops22h 39m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$253
One-way flights from Knoxville to MesaSearch for one-way flight options from Knoxville to Mesa. Find affordable one-way fares based on user searches. Data last updated April 18, 2026.
Search for one-way flight options from Knoxville to Mesa. Find affordable one-way fares based on user searches. Data last updated April 18, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/308:00 am
TYS
- PHX
Nonstop4h 06m
Allegiant Air
Deal found 4/15![Allegiant Air logo]()
$80
This Cheapflightsfares deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/182:42 pm
TYS
- PHX
Nonstop3h 48m
Allegiant Air
Deal found 4/13![Allegiant Air logo]()
$95
This Cheapflightsfares deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/62:34 pm
TYS
- PHX
Nonstop3h 58m
Allegiant Air
Deal found 4/14![Allegiant Air logo]()
$103
This Expedia deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/304:28 pm
TYS
- PHX
1 stop18h 08m
Frontier
Deal found 4/15![Frontier logo]()
$106
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/85:30 pm
TYS
- PHX
1 stop22h 12m
Multiple Airlines
Deal found 4/15![Multiple Airlines logo]()
$109
This Cheapflightsfares deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/112:42 pm
TYS
- PHX
Nonstop3h 48m
Allegiant Air
Deal found 4/16![Allegiant Air logo]()
$111
This Super.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/268:00 am
TYS
- PHX
Nonstop4h 06m
Allegiant Air
Deal found 4/16![Allegiant Air logo]()
$116
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1411:27 am
TYS
- PHX
2 stops36h 06m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$117
This Cheapflightsfares deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/148:00 am
TYS
- PHX
Nonstop4h 06m
Allegiant Air
Deal found 4/16![Allegiant Air logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/142:42 pm
TYS
- PHX
Nonstop3h 48m
Allegiant Air
Deal found 4/16![Allegiant Air logo]()
$121
Find flight deals from Knoxville to Mesa
Keep the following information in mind while searching for Knoxville to Mesa flight deals. Data was last updated April 18, 2026.
Round-trip from | $172 (Trip.com) |
|---|---|
One-way from | $80 (Kiwi.com) |
Popular in | November |
Cheapest in | September |
Average price | $343 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 18, 2026.
Use the filters below to find and compare flights from Knoxville to Mesa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvillePhoenix
TYS - PHX
TYSPHX
Knoxville McGhee Tyson
Wed 5/27
5:50 pm-10:30 pm
1 stop7h 40m
Phoenix Sky Harbor Intl
Sat 5/30
7:00 am-6:30 pm
2 stops8h 30m
$372
KnoxvillePhoenix
TYS - PHX
TYSPHX
Knoxville McGhee Tyson
Mon 5/18
8:32 pm-10:05 am
1 stop16h 33m
Phoenix Sky Harbor Intl
Thu 5/21
1:05 pm-11:37 pm
2 stops31h 32m
$392
Quickest round-trip
KnoxvillePhoenix
TYS - PHX
TYSPHX
Knoxville McGhee Tyson
Sat 9/12
6:30 am-11:01 am
1 stop7h 31m
Phoenix Sky Harbor Intl
Sat 9/19
1:31 pm-10:38 pm
1 stop6h 07m
$399
KnoxvillePhoenix
TYS - PHX
TYSPHX
Knoxville McGhee Tyson
Mon 5/18
8:32 pm-10:05 am
1 stop16h 33m
Phoenix Sky Harbor Intl
Thu 5/21
4:17 pm-7:24 pm
1 stop24h 07m
$422
KnoxvillePhoenix
TYS - PHX
TYSPHX
Knoxville McGhee Tyson
Sat 9/12
6:50 am-1:20 pm
2 stops9h 30m
Phoenix Sky Harbor Intl
Sat 9/19
6:00 am-7:20 pm
1 stop10h 20m
$439
KnoxvillePhoenix
TYS - PHX
TYSPHX
Knoxville McGhee Tyson
Mon 10/5
4:00 pm-10:00 pm
1 stop9h 00m
Phoenix Sky Harbor Intl
Fri 10/9
11:50 pm-11:55 am
1 stop9h 05m
$439
KnoxvillePhoenix
TYS - PHX
TYSPHX
Knoxville McGhee Tyson
Thu 5/14
2:45 pm-10:05 pm
2 stops10h 20m
Phoenix Sky Harbor Intl
Tue 5/19
8:55 am-7:40 pm
2 stops7h 45m
$451
KnoxvillePhoenix
TYS - PHX
TYSPHX
Knoxville McGhee Tyson
Wed 5/13
8:15 am-3:15 pm
2 stops10h 00m
Phoenix Sky Harbor Intl
Wed 5/20
8:10 am-7:40 pm
2 stops8h 30m
$464
KnoxvillePhoenix
TYS - PHX
TYSPHX
Knoxville McGhee Tyson
Thu 5/7
6:01 pm-10:01 pm
1 stop7h 00m
Phoenix Sky Harbor Intl
Mon 5/11
11:30 pm-10:06 am
1 stop7h 36m
$467
Cheapest one-way
KnoxvillePhoenix
TYS - PHX
TYSPHX
Knoxville McGhee Tyson
Mon 6/8
5:30 pm-12:42 pm
1 stop22h 12m
$109
Showing 1-10 of 20 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Mesa
Have a flexible travel schedule? Discover the best time to fly to Mesa from Knoxville with our price prediction graph.
TYS-PHX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Mesa
TYS-MS9
TYS-PHX
How far ahead should I book a flight from Knoxville to Mesa?
Use this chart to determine the optimal time to book a round-trip flight from Knoxville to Mesa. Price data was last updated on April 10, 2026.
Booking 36 days in advance of your planned departure date is, on average, the best time to get cheap flights from Knoxville to Mesa. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest time of day to fly from TYS to MS9?
Find hourly flight availability from Knoxville to Mesa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 18, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Knoxville to Mesa as you normally would.
How much does it cost to fly round-trip from Knoxville to Mesa?
Reviews of airlines servicing Mesa
Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated April 18, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAllegiant Air from Knoxville to Mesa to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Boarding
8.1
Entertainment
7.8
Overall
7.9
Comfort
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Boarding
8.1
Entertainment
7.8
Overall
7.9
Comfort
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Boarding
8.1
Entertainment
7.8
Overall
7.9
Comfort
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Boarding
8.1
Entertainment
7.8
Overall
7.9
Comfort
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Boarding
8.1
Entertainment
7.8
Overall
7.9
Comfort
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Boarding
8.1
Entertainment
7.8
Overall
7.9
Comfort
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
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Knoxville and Mesa flights
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| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$70 | Average$324 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$115 | Average$237 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$128 | Average$323 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$170 | Average$424 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$260 | Average$404 | FlexibilityNo cancel fee | On-time71% |