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McAllen

$300+ Cheap flights from Knoxville to McAllen (TYS - MFE)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/16. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MFE
Apr 12 — Apr 191
Sun 4/12
Sun 4/19
1 adult, Economy
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Cheap flight deals from Knoxville to McAllen

Cheapest flights from Knoxville to McAllen
Explore the most affordable flight options available from Knoxville to McAllen. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 13, 2026.

This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:00 am
TYS
-
MFE
1 stop7h 29m
American Airlines
Wed 4/291:10 pm
MFE
-
TYS
2 stops9h 49m
American Airlines
Deal found 3/8$300
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/115:30 am
TYS
-
MFE
2 stops7h 53m
Delta
Mon 6/1512:48 pm
MFE
-
TYS
2 stops9h 58m
Delta
Deal found 3/10$329
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/228:15 pm
TYS
-
MFE
1 stop5h 07m
American Airlines
Tue 6/27:00 am
MFE
-
TYS
1 stop5h 02m
American Airlines
Deal found 3/10$406
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/105:15 pm
TYS
-
MFE
1 stop6h 44m
United Airlines
Tue 4/145:17 am
MFE
-
TYS
1 stop13h 39m
United Airlines
Deal found 3/7$493
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1010:05 pm
TYS
-
MFE
1 stop12h 48m
Allegiant Air
Thu 7/168:44 pm
MFE
-
TYS
1 stop16h 13m
Allegiant Air
Deal found 3/11$503

Find flight deals from Knoxville to McAllen

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to McAllen (MFE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 13, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$300
(American Airlines)

Popular in

July

Cheapest in

April

Average price

$398
Provider with most accurate pricing for Knoxville McGhee Tyson-McAllen Miller Intl flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-McAllen Miller Intl flights.
Search Deals
From Knoxville McGhee Tyson to McAllen Miller Intl
Search Deals
Highest demand for flights based on searches. 23% potential increase in price ($154 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($37 potential savings vs. average RT price).
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Average for round-trip flights in March 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to McAllen that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 13, 2026.
Use the filters below to find and compare flights from Knoxville to McAllen that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleMcAllen

TYS - MFE

TYSMFE

Knoxville McGhee Tyson

Thu 4/16

6:00 am-12:29 pm

1 stop7h 29m

McAllen Miller Intl

Wed 4/29

1:10 pm-11:59 pm

2 stops9h 49m

$300
Quickest round-trip

KnoxvilleMcAllen

TYS - MFE

TYSMFE

Knoxville McGhee Tyson

Fri 5/22

8:15 pm-12:22 am

1 stop5h 07m

McAllen Miller Intl

Tue 6/2

7:00 am-1:02 pm

1 stop5h 02m

$406

KnoxvilleMcAllen

TYS - MFE

TYSMFE

Knoxville McGhee Tyson

Fri 4/10

5:15 pm-10:59 pm

1 stop6h 44m

McAllen Miller Intl

Tue 4/14

5:17 am-7:56 pm

1 stop13h 39m

$493

KnoxvilleMcAllen

TYS - MFE

TYSMFE

Knoxville McGhee Tyson

Fri 7/10

10:05 pm-9:53 am

1 stop12h 48m

McAllen Miller Intl

Thu 7/16

8:44 pm-7:13 pm

2 stops21h 29m

$521
Cheapest one-way
Quickest one-way

KnoxvilleMcAllen

TYS - MFE

TYSMFE

Knoxville McGhee Tyson

Mon 3/23

4:29 pm-11:06 pm

1 stop7h 37m

$324

KnoxvilleMcAllen

TYS - MFE

TYSMFE

Knoxville McGhee Tyson

Mon 3/23

1:53 pm-10:59 pm

2 stops10h 06m

$329

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/12

Sorted by cheapest first

Compare providers for flights from Knoxville to McAllen

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to McAllen in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-McAllen flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-McAllen flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-McAllen flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-McAllen flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-McAllen flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to McAllen

Have a flexible travel schedule? Discover the best time to fly to McAllen from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing McAllen

Get insights into the airlines that provide service to McAllen. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to McAllen. Reviews last updated March 13, 2026.
Get a feel of what it's like to fly with American Airlines from Knoxville to McAllen by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,446 reviews

Food

6.4

Crew

7.9

Boarding

7.5

Entertainment

6.9

Comfort

7.2

Overall

7.1

Reviews

1 / 20
8.0
Excellent

Monica,Nov 2025

JAC - DFW

At least there was an option of entertainment on this flight.
American Airlines
7.1
Good
11,446 reviews
American Airlines
7.1
Good
11,446 reviews

Food

6.4

Crew

7.9

Boarding

7.5

Entertainment

6.9

Comfort

7.2

Overall

7.1

Reviews

1 / 20
8.0
Excellent

Monica,Nov 2025

JAC - DFW

At least there was an option of entertainment on this flight.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to McAllen. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to McAllen?

    For as low as $300, American Airlines can have you in McAllen from Knoxville in 7h 29m. There are 1072 mi between Knoxville and McAllen.

  • What is the cheapest airline to fly from Knoxville to McAllen round-trip?

    Our cheapest airline available from Knoxville to McAllen is American Airlines. Our recent data shows that you can find tickets from as low as $278 on this airline. American Airlines is 44% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Knoxville to McAllen that include hotel bookings?

    Yes. In addition to deals on Knoxville to McAllen flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to McAllen?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to McAllen.

  • Can I find deals for business class flights from Knoxville to McAllen?

    Yes. Cheapflights offers flight deals from Knoxville to McAllen by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near McAllen?

Book flights to McAllen if you plan to visit one of these locations
Pharr
Weslaco
Mission
Edinburg

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Top airline flying from Knoxville to McAllen

Discover the top airline that operate flights from Knoxville to McAllen. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 13, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$278Average$414FlexibilityNo cancel feeOn-time71%

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