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$322+ Cheap flights from Knoxville (TYS) to Manchester (MAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/26. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MAN
Feb 26 — Mar 51
Thu 2/26
Thu 3/5
1 adult, Economy
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Cheap flight deals from Knoxville to Manchester

Cheapest flights from Knoxville to Manchester
Explore the most affordable flight options available from Knoxville to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.

This Delta deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1110:04 am
TYS
-
MAN
1 stop20h 26m
Delta
Wed 3/181:30 pm
MAN
-
TYS
1 stop14h 27m
Delta
Deal found 1/24$624
This oojo deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/96:10 am
TYS
-
MAN
2 stops27h 50m
British Airways
Mon 3/168:05 pm
MAN
-
TYS
2 stops28h 52m
British Airways
Deal found 1/25$626
This Virgin Atlantic deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1112:03 pm
TYS
-
MAN
2 stops15h 52m
Virgin Atlantic
Wed 3/181:30 pm
MAN
-
TYS
1 stop14h 27m
Virgin Atlantic
Deal found 1/24$629
This United Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2510:53 am
TYS
-
MAN
2 stops18h 27m
United Airlines
Sun 3/16:00 am
MAN
-
TYS
2 stops33h 12m
United Airlines
Deal found 1/25$653
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/205:54 pm
TYS
-
MAN
2 stops15h 06m
Delta
Tue 5/121:00 pm
MAN
-
TYS
1 stop32h 53m
Delta
Deal found 1/26$656
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/205:54 pm
TYS
-
MAN
2 stops15h 06m
Delta
Wed 5/133:20 pm
MAN
-
TYS
2 stops24h 46m
Delta
Deal found 1/26$660
This United Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/92:21 pm
TYS
-
MAN
2 stops15h 59m
United Airlines
Mon 3/166:00 am
MAN
-
TYS
3 stops42h 47m
United Airlines
Deal found 1/25$663
This Air France deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/205:54 pm
TYS
-
MAN
2 stops15h 06m
Multiple Airlines
Tue 5/125:55 am
MAN
-
TYS
2 stops15h 58m
Multiple Airlines
Deal found 1/26$664
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/187:20 pm
TYS
-
MAN
2 stops34h 05m
United Airlines
Wed 5/137:00 am
MAN
-
TYS
2 stops21h 44m
United Airlines
Deal found 1/26$668
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1510:05 am
TYS
-
MAN
1 stop15h 50m
Delta
Thu 12/31:30 pm
MAN
-
TYS
1 stop15h 16m
Delta
Deal found 1/27$682
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1510:05 am
TYS
-
MAN
2 stops17h 15m
Delta
Fri 12/41:25 pm
MAN
-
TYS
1 stop15h 21m
Delta
Deal found 1/27$691
This United Airlines deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/111:53 pm
TYS
-
MAN
2 stops16h 27m
United Airlines
Wed 3/186:10 am
MAN
-
TYS
3 stops18h 37m
United Airlines
Deal found 1/24$699

Find flight deals from Knoxville to Manchester

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Manchester (MAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$624
(Delta)

One-way from

$322
(Kiwi.com)

Popular in

September

Cheapest in

January

Average price

$622
Provider with most accurate pricing for Knoxville McGhee Tyson-Manchester flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Manchester flights.
Search Deals
From Knoxville McGhee Tyson to Manchester
Search Deals
One-way flight from Knoxville McGhee Tyson to Manchester
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($70 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($44 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from Knoxville to Manchester that are best for you.

Fly from

Knoxville

Fly to

Manchester

Route

Depart

Return

Price

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Wed 3/11

10:04 am-10:30 am

1 stop20h 26m

Manchester

Wed 3/18

1:30 pm-11:57 pm

1 stop14h 27m

$624

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Wed 3/11

12:03 pm-7:55 am

2 stops15h 52m

Manchester

Wed 3/18

1:30 pm-11:57 pm

1 stop14h 27m

$629

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Wed 2/25

9:40 am-10:20 am

2 stops19h 40m

Manchester

Sun 3/1

6:00 am-8:37 pm

2 stops19h 37m

$653

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Mon 3/9

2:21 pm-10:20 am

2 stops15h 59m

Manchester

Mon 3/16

6:00 am-8:47 pm

3 stops42h 47m

$663

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Sat 4/18

7:20 pm-10:25 am

2 stops34h 05m

Manchester

Fri 5/8

6:05 am-5:11 pm

2 stops16h 06m

$668

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Wed 4/22

9:40 am-10:25 am

2 stops19h 45m

Manchester

Wed 5/13

6:05 am-10:49 am

2 stops33h 44m

$668

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Wed 4/22

2:25 pm-10:25 am

2 stops15h 00m

Manchester

Thu 5/14

6:05 am-10:49 am

2 stops33h 44m

$668

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Sun 4/19

9:40 am-10:25 am

2 stops19h 45m

Manchester

Tue 5/12

6:05 am-8:12 pm

2 stops19h 07m

$668

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Wed 4/22

2:25 pm-10:25 am

2 stops15h 00m

Manchester

Mon 5/11

11:10 am-10:49 am

2 stops52h 39m

$700

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Thu 3/26

7:30 am-9:15 am

3 stops45h 45m

$322

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Showing 1-10 of 15 results
1
2

Compare providers for flights from Knoxville to Manchester

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Manchester in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Manchester flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Manchester flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Manchester flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Manchester flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Manchester flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Manchester

What is the cheapest month to book a flight from Knoxville to Manchester?

Currently, January is the cheapest month in which you can book a flight from Knoxville to Manchester (average of $573). Flying from Knoxville to Manchester in June is currently the most expensive (average of $992). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Manchester

Get insights into the airlines that provide service to Manchester. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Manchester. Reviews last updated January 27, 2026.
See what other customers who have flown with Delta, Virgin Atlantic, and American Airlines from Knoxville to Manchester have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,121 reviews

Crew

8.5

Comfort

7.9

Food

7.2

Overall

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,121 reviews
Delta
7.9
Good
8,121 reviews

Crew

8.5

Comfort

7.9

Food

7.2

Overall

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Virgin Atlantic
7.5
Good
678 reviews
Delta
7.9
Good
8,121 reviews

Crew

8.5

Comfort

7.9

Food

7.2

Overall

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,198 reviews
Delta
7.9
Good
8,121 reviews

Crew

8.5

Comfort

7.9

Food

7.2

Overall

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Manchester?

    There are many flights that can get you from Knoxville to Manchester in 15h 52m. Fly via Delta, Virgin Atlantic, or United Airlines to get the fastest option. The distance between Knoxville and Manchester is about 3961 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Knoxville to Manchester round-trip?

    Delta, at $622, was found to be the cheapest airline from Knoxville to Manchester.Alternate airlines to your destination round-trip include Virgin Atlantic and American Airlines. Delta is currently priced 29% below the average price you’ll pay for this route.

  • Can I find deals for flights from Knoxville to Manchester that include hotel bookings?

    Yes. In addition to deals on Knoxville to Manchester flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Manchester.

  • Can I find deals for business class flights from Knoxville to Manchester?

    Yes. Cheapflights offers flight deals from Knoxville to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Manchester?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to Manchester (average of $573). Flying from Knoxville to Manchester in June is currently the most expensive (average of $992). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
Bury
Salford
Bolton
Barrow-in-Furness
Buxton
Huddersfield
Southport
Wakefield
Stockport
Derby
Bromborough
Lancaster
Llandudno
Conwy
Morecambe

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Alternative routes for Knoxville to Manchester

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Knoxville to Manchester

Discover the top 3 airlines that operate flights from Knoxville to Manchester. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$622Average$776FlexibilityNo cancel feeOn-timeN/A
Virgin AtlanticCheapest$730Average$1,342FlexibilityNo cancel feeOn-time72%
American AirlinesCheapest$747Average$1,062FlexibilityNo cancel feeOn-time71%

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