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$635+ Cheap flights from Knoxville (TYS) to Manchester (MAN)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/7. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MAN
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Knoxville to Manchester

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Manchester (MAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$635
(Virgin Atlantic)

Popular in

June

Cheapest in

November

Average price

$877
From Knoxville McGhee Tyson to Manchester
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($160 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($43 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Knoxville to Manchester

Cheapest flights from Knoxville to Manchester
Explore the most affordable flight options available from Knoxville to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Virgin Atlantic deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/72:55 pmTYS - MAN
1 stop12h 40mVirgin Atlantic
Tue 10/1412:35 pmMAN - TYS
1 stop15h 32mVirgin Atlantic
Deal found 9/9$635
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/77:11 amTYS - MAN
2 stops19h 24mDelta
Tue 10/142:15 pmMAN - TYS
2 stops23h 45mDelta
Deal found 9/9$640
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/45:52 pmTYS - MAN
2 stops33h 33mUnited Airlines
Sat 10/1111:35 amMAN - TYS
2 stops51h 35mUnited Airlines
Deal found 9/10$769
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/102:00 pmTYS - MAN
2 stops22h 20mUnited Airlines
Sat 10/259:10 amMAN - TYS
2 stops19h 42mUnited Airlines
Deal found 9/11$789
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/258:26 amTYS - MAN
2 stops27h 34mUnited Airlines
Sun 11/3012:50 pmMAN - TYS
2 stops54h 53mUnited Airlines
Deal found 9/9$819
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/255:25 amTYS - MAN
1 stop24h 05mDelta
Sun 11/309:05 amMAN - TYS
1 stop16h 01mDelta
Deal found 9/9$856
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/102:27 pmTYS - MAN
1 stop13h 08mDelta
Sat 10/255:55 amMAN - TYS
2 stops20h 18mDelta
Deal found 9/10$879
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/18:04 pmTYS - MAN
2 stops15h 26mAmerican Airlines
Wed 12/318:55 amMAN - TYS
2 stops17h 19mAmerican Airlines
Deal found 9/10$937
This Air Canada deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/109:55 amTYS - MAN
3 stops19h 30mAir Canada
Sat 10/256:05 amMAN - TYS
3 stops20h 06mAir Canada
Deal found 9/9$980
This Mytrip deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/102:00 pmTYS - MAN
2 stops15h 40mMultiple Airlines
Sun 9/1411:50 amMAN - TYS
2 stops41h 07mMultiple Airlines
Deal found 9/9$994

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Knoxville to Manchester that are best for you.

Fly from

Knoxville

Fly to

Manchester

Route

Depart

Return

Price

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Tue 10/7

2:55 pm-8:35 am

1 stop12h 40m

Manchester

Tue 10/14

12:35 pm-11:07 pm

1 stop15h 32m

$635

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Tue 10/7

7:11 am-7:35 am

2 stops19h 24m

Manchester

Tue 10/14

2:15 pm-9:00 am

2 stops23h 45m

$640

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Sat 10/4

5:52 pm-8:25 am

2 stops33h 33m

Manchester

Sat 10/11

11:35 am-10:10 am

2 stops51h 35m

$769

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Fri 10/10

2:16 pm-5:20 pm

2 stops22h 04m

Manchester

Sat 10/25

6:05 am-11:52 pm

2 stops22h 47m

$789

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Tue 11/25

8:26 am-5:00 pm

2 stops27h 34m

Manchester

Sun 11/30

12:50 pm-2:43 pm

2 stops54h 53m

$819

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Tue 11/25

5:25 am-10:30 am

1 stop24h 05m

Manchester

Sun 11/30

9:05 am-8:06 pm

1 stop16h 01m

$856

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Fri 10/10

2:27 pm-8:35 am

1 stop13h 08m

Manchester

Sat 10/25

5:55 am-9:13 pm

2 stops20h 18m

$879

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Mon 12/1

4:15 pm-2:00 pm

2 stops16h 45m

Manchester

Wed 12/31

8:55 am-7:41 pm

2 stops15h 46m

$937

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Best time to book a flight from Knoxville to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Manchester

What is the cheapest month to book a flight from Knoxville to Manchester?

Currently, January is the cheapest month in which you can book a flight from Knoxville to Manchester (average of $645). Flying from Knoxville to Manchester in June is currently the most expensive (average of $1,010). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to MAN?

Find hourly flight availability from Knoxville to Manchester. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

A simple way to save on the total cost of your ticket is to fly from Knoxville to Manchester in the evening. If you’re flexible enough to do this you can expect to save up to 32% on your trip compared to booking a flight in the afternoon.

Reviews of airlines servicing Manchester

Get insights into the airlines that provide service to Manchester. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Manchester. Reviews last updated September 11, 2025.
See what other customers who have flown with Delta, Virgin Atlantic, and American Airlines from Knoxville to Manchester have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Virgin Atlantic
7.4
Good
664 reviews
Delta
8.0
Very good
7,960 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Manchester?

    There are many flights that can get you from Knoxville to Manchester in 12h 40m. Fly via Virgin Atlantic, Delta, or United Airlines to get the fastest option. The distance between Knoxville and Manchester is about 3961 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Knoxville to Manchester round-trip?

    Delta, at $702, was found to be the cheapest airline from Knoxville to Manchester.Alternate airlines to your destination round-trip include Virgin Atlantic and American Airlines. Delta is currently priced 24% below the average price you’ll pay for this route.

  • Can I find deals for flights from Knoxville to Manchester that include hotel bookings?

    Yes. In addition to deals on Knoxville to Manchester flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Manchester.

  • Can I find deals for business class flights from Knoxville to Manchester?

    Yes. Cheapflights offers flight deals from Knoxville to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Manchester?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to Manchester (average of $645). Flying from Knoxville to Manchester in June is currently the most expensive (average of $1,010). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
Bury
Salford
Southport
Bolton
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Preston
Crewe
Buxton
Huddersfield
Wakefield
Stockport
Derby
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Bradford
Llandudno
Conwy
Morecambe
Ambleside

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Alternative routes for Knoxville to Manchester

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Top 3 airlines flying from Knoxville to Manchester

Discover the top 3 airlines that operate flights from Knoxville to Manchester. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$702Average$858FlexibilityNo cancel feeOn-timeN/A
Virgin AtlanticCheapest$730Average$1,267FlexibilityNo cancel feeOn-time72%
American AirlinesCheapest$798Average$1,062FlexibilityNo cancel feeOn-time71%

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