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$207+ Cheap flights from Syracuse to Louisville (SYR - SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/21. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — SDF
Dec 6 — Dec 131
Sat 12/6
Sat 12/13
1 adult, Economy
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Find flight deals from Syracuse to Louisville

Cheapest flights from Syracuse to Louisville
Explore the most affordable flight options available from Syracuse to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:01 pmSYR - SDF
1 stop4h 58mDelta
Sat 12/137:15 amSDF - SYR
1 stop6h 08mDelta
Deal found 11/5$249
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1411:34 amSYR - SDF
1 stop28h 02mAllegiant Air
Fri 12/199:54 amSDF - SYR
1 stop24h 00mAllegiant Air
Deal found 11/5$262
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1411:34 amSYR - SDF
1 stop28h 02mAllegiant Air
Thu 12/189:21 pmSDF - SYR
1 stop20h 39mAllegiant Air
Deal found 11/5$263
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/128:20 pmSYR - SDF
2 stops38h 40mMultiple Airlines
Fri 12/199:54 amSDF - SYR
1 stop24h 00mMultiple Airlines
Deal found 11/5$287
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/128:20 pmSYR - SDF
2 stops38h 40mMultiple Airlines
Thu 12/189:21 pmSDF - SYR
1 stop20h 39mMultiple Airlines
Deal found 11/5$289
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1410:15 amSYR - SDF
2 stops22h 43mMultiple Airlines
Fri 12/199:54 amSDF - SYR
1 stop24h 00mMultiple Airlines
Deal found 11/5$318
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1410:15 amSYR - SDF
2 stops22h 43mMultiple Airlines
Thu 12/189:21 pmSDF - SYR
1 stop20h 39mMultiple Airlines
Deal found 11/5$319
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/136:00 amSYR - SDF
2 stops11h 16mUnited Airlines
Tue 12/1612:20 pmSDF - SYR
1 stop4h 22mUnited Airlines
Deal found 11/5$324
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/136:00 amSYR - SDF
2 stops11h 16mUnited Airlines
Wed 12/171:50 pmSDF - SYR
2 stops9h 29mUnited Airlines
Deal found 11/5$329
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/157:21 pmSYR - SDF
1 stop21h 34mMultiple Airlines
Fri 12/195:05 amSDF - SYR
2 stops14h 12mMultiple Airlines
Deal found 11/5$359
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2110:26 amSYR - SDF
1 stop4h 19mUnited Airlines
Sun 11/239:55 amSDF - SYR
1 stop4h 16mUnited Airlines
Deal found 11/5$369
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1212:18 pmSYR - SDF
1 stop6h 34mDelta
Tue 12/1610:44 amSDF - SYR
2 stops12h 22mDelta
Deal found 11/5$372

Cheap flight deals from Syracuse to Louisville

Discover tips and strategies to find the most affordable flight options for your journey from Syracuse (SYR) to Louisville (SDF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$249
(Delta)

One-way from

$207
(Kiwi.com)

Popular in

September

Cheapest in

August

Average price

$326
Provider with most accurate pricing for Syracuse Hancock Intl-Louisville Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Syracuse Hancock Intl-Louisville Intl flights.
Search Deals
From Syracuse Hancock Intl to Louisville Intl
Search Deals
One-way flight from Syracuse Hancock Intl to Louisville Intl
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($23 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Syracuse to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Syracuse to Louisville that are best for you.

Fly from

Syracuse

Fly to

Louisville

Route

Depart

Return

Price

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Sat 2/21

3:00 pm-8:25 pm

1 stop5h 25m

Louisville Intl

Wed 2/25

6:00 am-11:37 am

1 stop5h 37m

$249

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Fri 12/12

7:01 pm-11:59 pm

1 stop4h 58m

Louisville Intl

Tue 12/16

10:44 am-4:00 pm

1 stop5h 16m

$249

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Sat 12/13

2:18 pm-7:12 pm

1 stop4h 54m

Louisville Intl

Fri 12/19

6:16 pm-11:20 pm

1 stop5h 04m

$249

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Sat 12/13

2:18 pm-7:12 pm

1 stop4h 54m

Louisville Intl

Mon 12/15

7:50 am-12:08 pm

1 stop4h 18m

$249

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Fri 12/12

7:01 pm-11:59 pm

1 stop4h 58m

Louisville Intl

Fri 12/19

6:16 pm-11:20 pm

1 stop5h 04m

$249

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Sat 12/13

2:18 pm-7:12 pm

1 stop4h 54m

Louisville Intl

Tue 12/16

12:58 pm-5:56 pm

1 stop4h 58m

$249

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Sat 12/13

2:18 pm-7:12 pm

1 stop4h 54m

Louisville Intl

Wed 12/17

10:44 am-4:00 pm

1 stop5h 16m

$249

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Fri 12/12

12:18 pm-6:52 pm

1 stop6h 34m

Louisville Intl

Wed 12/17

10:44 am-4:00 pm

1 stop5h 16m

$249

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Fri 12/12

8:20 pm-11:00 am

2 stops38h 40m

Louisville Intl

Fri 12/19

9:54 am-9:54 am

1 stop24h 00m

$287

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Sat 2/21

3:25 pm-12:25 am

2 stops9h 00m

Louisville Intl

Wed 2/25

6:00 am-11:34 am

1 stop5h 34m

$324

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/6

Showing 1-10 of 19 results
1
2

Compare providers for flights from Syracuse to Louisville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Syracuse to Louisville in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Syracuse-Louisville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Syracuse-Louisville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Syracuse-Louisville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Syracuse-Louisville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Syracuse-Louisville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Syracuse to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Louisville

What is the cheapest month to book a flight from Syracuse to Louisville?

Currently, April is the cheapest month in which you can book a flight from Syracuse to Louisville (average of $117). Flying from Syracuse to Louisville in February is currently the most expensive (average of $262). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SYR to SDF?

Find hourly flight availability from Syracuse to Louisville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 6, 2025.

When flying from Syracuse to Louisville, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 45% versus a flight in the evening.

Reviews of airlines servicing Louisville

Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated November 6, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Syracuse to Louisville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,001 reviews

Overall

7.9

Entertainment

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
7.9
Good
8,001 reviews
Delta
7.9
Good
8,001 reviews

Overall

7.9

Entertainment

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
9,007 reviews
Delta
7.9
Good
8,001 reviews

Overall

7.9

Entertainment

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
11,040 reviews
Delta
7.9
Good
8,001 reviews

Overall

7.9

Entertainment

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Syracuse to Louisville?

    A quick flight from Syracuse to Louisville can take about 5h 25m. Delta provides one of the quickest options available for as low as $249. The distance between Syracuse and Louisville is about 608 mi.

  • What are the cheapest airlines flying from Syracuse to Louisville round-trip?

    According to our current data, Delta ($232), American Airlines ($244), and United Airlines ($271) offers the cheapest pricing from Syracuse to Louisville. Users have found that Delta is 35% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Syracuse to Louisville one-way?

    $233 is the cheapest one-way deal found within the past few days, from Allegiant Air. You may also be able to find cheap deals on American Airlines and Delta, with prices starting from $239 and $239, respectively.

  • Can I find deals for flights from Syracuse to Louisville that include hotel bookings?

    Yes. In addition to deals on Syracuse to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Louisville.

  • Can I find deals for business class flights from Syracuse to Louisville?

    Yes. Cheapflights offers flight deals from Syracuse to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to Louisville?

    Currently, April is the cheapest month in which you can book a flight from Syracuse to Louisville (average of $117). Flying from Syracuse to Louisville in February is currently the most expensive (average of $262). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Jeffersonville
Elizabethtown
Corydon
Bardstown

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Top 3 airlines flying from Syracuse to Louisville

Discover the top 3 airlines that operate flights from Syracuse to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$232Average$308FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$244Average$333FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$271Average$387FlexibilityNo cancel feeOn-time69%

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