How long is the flight from Syracuse to Louisville?

A quick flight from Syracuse to Louisville can take about 5h 29m. American Airlines provides one of the quickest options available for as low as $249. The distance between Syracuse and Louisville is about 608 mi. This flight may include one or multiple stops.

What are the cheapest airlines flying from Syracuse to Louisville round-trip?

According to our current data, Delta ($182), American Airlines ($248), and United Airlines ($271) offers the cheapest pricing from Syracuse to Louisville. Users have found that Delta is 50% cheaper than the other options available to this destination.

What are the cheapest airlines to fly from Syracuse to Louisville one-way?

$125 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on American Airlines and United Airlines, with prices starting from $168 and $168, respectively.

In terms of precipitation, rainfall in Louisville ranges from 3.1 - 5.3 inches per month. May is typically the wettest month, when rainfall can reach 5.3 in. September is typically the driest time to visit Louisville when rainfall is around 3.1 in.

If weather is an important factor for your trip to Louisville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 35.6 F).

What are the most popular airlines that fly from Syracuse to Louisville?

Consider American Airlines, Delta or United Airlines when booking your flight. These represent the most popular airlines when flying from Syracuse to Louisville.

Most accurate provider : When it comes to deals on Syracuse-Louisville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Syracuse-Louisville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Syracuse-Louisville flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Syracuse-Louisville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Syracuse-Louisville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Syracuse to Louisville that include hotel bookings?

Yes. In addition to deals on Syracuse to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Syracuse to Louisville?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Louisville.

Can I find deals for business class flights from Syracuse to Louisville?

Yes. Cheapflights offers flight deals from Syracuse to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$226+ Flights from Syracuse to Louisville

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Cheap flight deals from Syracuse to Louisville

Cheapest flights from Syracuse to Louisville
Explore the most affordable flight options available from Syracuse to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 12, 2025.

vie. 12/266:15 amSYR - SDF

1 stop6h 58mUnited Airlines

mar. 12/302:00 pmSDF - SYR

1 stop7h 09mUnited Airlines

Deal found 12/10

$359

sáb. 12/136:00 amSYR - SDF

1 stop4h 04mDelta

lun. 12/156:16 pmSDF - SYR

1 stop5h 17mDelta

Deal found 12/10

$369

sáb. 12/136:15 amSYR - SDF

1 stop6h 57mUnited Airlines

mié. 12/1712:20 pmSDF - SYR

2 stops10h 59mUnited Airlines

Deal found 12/11

$374

sáb. 12/1310:29 amSYR - SDF

1 stop4h 16mUnited Airlines

sáb. 12/202:00 pmSDF - SYR

1 stop7h 09mUnited Airlines

Deal found 12/11

$382

sáb. 12/131:05 pmSYR - SDF

1 stop7h 23mUnited Airlines

lun. 12/151:50 pmSDF - SYR

2 stops9h 29mUnited Airlines

Deal found 12/10

$444

Best flights from Syracuse to Louisville
Discover carefully curated flight deals from Syracuse to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated diciembre 12, 2025.

vie. 1/95:09 amSYR - SDF

1 stop5h 29mAmerican Airlines

vie. 1/167:00 amSDF - SYR

1 stop5h 00mAmerican Airlines

Deal found 12/9

$249

sáb. 4/2511:55 amSYR - SDF

1 stop7h 06mDelta

mar. 4/285:00 pmSDF - SYR

1 stop6h 17mDelta

Deal found 12/10

$249

vie. 1/98:00 amSYR - SDF

1 stop5h 24mUnited Airlines

vie. 1/306:28 amSDF - SYR

1 stop6h 42mUnited Airlines

Deal found 12/10

$269

jue. 1/87:08 amSYR - SDF

1 stop5h 17mAmerican Airlines

jue. 1/157:00 amSDF - SYR

2 stops7h 38mAmerican Airlines

Deal found 12/11

$254

jue. 2/126:09 pmSYR - SDF

1 stop6h 15mAmerican Airlines

dom. 2/1510:00 amSDF - SYR

1 stop7h 19mAmerican Airlines

Deal found 12/11

$289

sáb. 1/318:00 amSYR - SDF

1 stop5h 28mUnited Airlines

mié. 2/49:50 amSDF - SYR

1 stop4h 17mUnited Airlines

Deal found 12/9

$319

vie. 1/92:15 pmSYR - SDF

2 stops7h 50mAmerican Airlines

vie. 1/306:00 amSDF - SYR

2 stops8h 38mAmerican Airlines

Deal found 12/10

$299

Last-minute flights from Syracuse to Louisville
Discover last-minute flight deals from Syracuse to Louisville. Data last updated diciembre 12, 2025 and is based on user searches.

jue. 1/86:15 amSYR - SDF

1 stop5h 29mDelta

jue. 1/156:00 amSDF - SYR

1 stop5h 37mDelta

Deal found 12/11

$249

jue. 1/87:08 amSYR - SDF

1 stop5h 17mAmerican Airlines

jue. 1/157:00 amSDF - SYR

2 stops7h 38mAmerican Airlines

Deal found 12/11

$254

vie. 1/98:00 amSYR - SDF

1 stop5h 24mUnited Airlines

vie. 1/306:28 amSDF - SYR

1 stop6h 42mUnited Airlines

Deal found 12/10

$269

vie. 1/97:00 amSYR - SDF

1 stop5h 32mAmerican Airlines

vie. 1/307:20 pmSDF - SYR

1 stop4h 07mAmerican Airlines

Deal found 12/10

$289

sáb. 1/318:00 amSYR - SDF

1 stop5h 28mUnited Airlines

mié. 2/49:50 amSDF - SYR

1 stop4h 17mUnited Airlines

Deal found 12/9

$319

One-way flights from Syracuse to Louisville
Search for one-way flight options from Syracuse to Louisville. Find affordable one-way fares based on user searches. Data last updated diciembre 12, 2025.

mié. 4/1511:49 amSYR - SDF

2 stops25h 37mBreeze Airways

Deal found 12/11

$226

jue. 1/15:26 pmSYR - SDF

1 stop4h 48mAmerican Airlines

Deal found 12/10

$239

jue. 1/15:45 amSYR - SDF

2 stops7h 28mUnited Airlines

Deal found 12/11

$254

mié. 3/253:25 pmSYR - SDF

2 stops7h 15mAmerican Airlines

Deal found 12/10

$324

mié. 3/253:48 pmSYR - SDF

3 stops21h 38mMultiple Airlines

Deal found 12/10

$411

vie. 12/1910:20 amSYR - SDF

1 stop7h 08mUnited Airlines

Deal found 12/11

$428

jue. 1/17:58 pmSYR - SDF

3 stops43h 09mMultiple Airlines

Deal found 12/11

$632

Find flight deals from Syracuse to Louisville

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$249 (Delta)
One-way from	$226 (Kiwi.com)
Popular in	September
Cheapest in	August
Average price	$441

Provider with most accurate pricing for Syracuse Hancock Intl-Louisville Intl flight deals.

Search Deals

Provider most trusted by Cheapflights users for Syracuse Hancock Intl-Louisville Intl flights.

Search Deals

From Syracuse Hancock Intl to Louisville Intl

Search Deals

One-way flight from Syracuse Hancock Intl to Louisville Intl

Search Deals

Highest demand for flights based on searches. 2% potential increase in price ($10 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 4% potential price decrease ($18 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Syracuse to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

vie. 1/9

5:09 am-10:38 am

1 stop5h 29m

Louisville Intl

vie. 1/16

7:00 am-12:00 pm

1 stop5h 00m

$249

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

sáb. 4/25

11:55 am-7:01 pm

1 stop7h 06m

Louisville Intl

mar. 4/28

5:00 pm-11:17 pm

1 stop6h 17m

$249

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

jue. 1/8

7:08 am-12:25 pm

1 stop5h 17m

Louisville Intl

jue. 1/15

7:00 am-2:38 pm

2 stops7h 38m

$254

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

vie. 1/9

8:00 am-1:24 pm

1 stop5h 24m

Louisville Intl

vie. 1/30

6:28 am-1:10 pm

1 stop6h 42m

$269

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

jue. 2/12

6:09 pm-12:24 am

1 stop6h 15m

Louisville Intl

dom. 2/15

10:00 am-5:19 pm

1 stop7h 19m

$289

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

vie. 1/9

2:15 pm-10:05 pm

2 stops7h 50m

Louisville Intl

vie. 1/30

6:00 am-2:38 pm

2 stops8h 38m

$299

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

sáb. 1/31

8:00 am-1:28 pm

1 stop5h 28m

Louisville Intl

mié. 2/4

9:50 am-2:07 pm

1 stop4h 17m

$319

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

mié. 4/15

11:49 am-1:26 pm

2 stops25h 37m

$226

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

jue. 1/1

5:26 pm-10:14 pm

1 stop4h 48m

$239

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

mié. 3/25

6:15 pm-11:57 pm

1 stop5h 42m

$239

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/11

Showing 1-10 of 15 results

Compare providers for flights from Syracuse to Louisville

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Syracuse to Louisville in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars
Priceline	Price Accuracy1 star	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Syracuse-Louisville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Syracuse-Louisville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Syracuse-Louisville flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Syracuse-Louisville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Syracuse-Louisville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Syracuse to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Syracuse with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Louisville

What is the cheapest month to book a flight from Syracuse to Louisville?

Currently, April is the cheapest month in which you can book a flight from Syracuse to Louisville (average of $117). Flying from Syracuse to Louisville in February is currently the most expensive (average of $262). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SYR to SDF?

When flying from Syracuse to Louisville, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 45% versus a flight in the evening.

Reviews of airlines servicing Louisville

Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Syracuse to Louisville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.9

Good

8,007 reviews

Reviews

1 / 20

10.0

Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Delta

7.9

Good

8,007 reviews

Delta

7.9

Good

8,007 reviews

Reviews

1 / 20

10.0

Excellent

Kymberlee,Oct 2024

JFK - ATL

United Airlines

7.4

Good

9,095 reviews

Delta

7.9

Good

8,007 reviews

Reviews

1 / 20

10.0

Excellent

Kymberlee,Oct 2024

JFK - ATL

American Airlines

7.2

Good

11,050 reviews

Delta

7.9

Good

8,007 reviews

Reviews

1 / 20

10.0

Excellent

Kymberlee,Oct 2024

JFK - ATL

Related info for your journey

How long is the flight from Syracuse to Louisville?
A quick flight from Syracuse to Louisville can take about 5h 29m. American Airlines provides one of the quickest options available for as low as $249. The distance between Syracuse and Louisville is about 608 mi. This flight may include one or multiple stops.
What are the cheapest airlines flying from Syracuse to Louisville round-trip?
According to our current data, Delta ($182), American Airlines ($248), and United Airlines ($271) offers the cheapest pricing from Syracuse to Louisville. Users have found that Delta is 50% cheaper than the other options available to this destination.
What are the cheapest airlines to fly from Syracuse to Louisville one-way?
$125 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on American Airlines and United Airlines, with prices starting from $168 and $168, respectively.
Can I find deals for flights from Syracuse to Louisville that include hotel bookings?
Yes. In addition to deals on Syracuse to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Syracuse to Louisville?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Louisville.
Can I find deals for business class flights from Syracuse to Louisville?
Yes. Cheapflights offers flight deals from Syracuse to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Syracuse to Louisville?
Currently, April is the cheapest month in which you can book a flight from Syracuse to Louisville (average of $117). Flying from Syracuse to Louisville in February is currently the most expensive (average of $262). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Shepherdsville

Jeffersonville

Elizabethtown

Corydon

Bardstown

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Top 3 airlines flying from Syracuse to Louisville

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$200	Average$338	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$248	Average$338	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$271	Average$387	FlexibilityNo cancel fee	On-time69%

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$226+ Cheap flights from Syracuse to Louisville (SYR - SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Syracuse to Louisville with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Syracuse to Louisville

Cheapest flights from Syracuse to LouisvilleExplore the most affordable flight options available from Syracuse to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 12, 2025.

Explore the most affordable flight options available from Syracuse to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 12, 2025.

Find flight deals from Syracuse to Louisville

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Syracuse to Louisville that are best for you.

Compare providers for flights from Syracuse to Louisville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Syracuse to Louisville in December.

Best time to book a flight from Syracuse to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Syracuse with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Louisville

What is the cheapest month to book a flight from Syracuse to Louisville?

What is the cheapest time of day to fly from SYR to SDF?

Reviews of airlines servicing Louisville

Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Syracuse to Louisville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Syracuse to Louisville?

What are the cheapest airlines flying from Syracuse to Louisville round-trip?

What are the cheapest airlines to fly from Syracuse to Louisville one-way?

Can I find deals for flights from Syracuse to Louisville that include hotel bookings?

How can I find direct flights from Syracuse to Louisville?

Can I find deals for business class flights from Syracuse to Louisville?

What is the cheapest month to book a flight from Syracuse to Louisville?

Traveling to a place near Louisville?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Syracuse to Louisville

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Syracuse to Louisville

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Cheapest flights from Syracuse to Louisville
Explore the most affordable flight options available from Syracuse to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 12, 2025.