$198+ Cheap flights from Syracuse to Louisville (SYR - SDF)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/19. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — SDF
Jun 12 — Jun 191
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Syracuse to Louisville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Syracuse to Louisville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Syracuse to LouisvilleExplore the most affordable flight options available from Syracuse to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 13, 2026.
Explore the most affordable flight options available from Syracuse to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 13, 2026.
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:05 am
SYR
- SDF
1 stop5h 48m
Delta
Sat 7/47:55 am
SDF
- SYR
1 stop4h 34m
Delta
Deal found 5/11![Delta logo]()
$299
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1810:18 am
SYR
- SDF
2 stops7h 29m
American Airlines
Tue 8/252:36 pm
SDF
- SYR
1 stop7h 18m
American Airlines
Deal found 5/10![American Airlines logo]()
$304
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:11 am
SYR
- SDF
1 stop3h 44m
Delta
Tue 6/306:34 pm
SDF
- SYR
1 stop5h 25m
Delta
Deal found 5/11![Delta logo]()
$309
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:05 am
SYR
- SDF
1 stop5h 48m
Delta
Fri 7/35:26 pm
SDF
- SYR
1 stop5h 31m
Delta
Deal found 5/11![Delta logo]()
$319
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/276:11 am
SYR
- SDF
1 stop3h 44m
Delta
Sat 7/47:55 am
SDF
- SYR
1 stop4h 34m
Delta
Deal found 5/11![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/276:11 am
SYR
- SDF
1 stop3h 44m
Delta
Sun 6/284:40 pm
SDF
- SYR
1 stop7h 19m
Delta
Deal found 5/11![Delta logo]()
$349
This Delta deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:00 am
SYR
- SDF
1 stop6h 21m
Delta
Thu 9/36:00 am
SDF
- SYR
1 stop5h 12m
Delta
Deal found 5/7![Delta logo]()
$354
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:00 am
SYR
- SDF
2 stops7h 11m
United Airlines
Tue 8/255:15 am
SDF
- SYR
2 stops8h 59m
United Airlines
Deal found 5/10![United Airlines logo]()
$359
This United Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:49 pm
SYR
- SDF
1 stop6h 00m
United Airlines
Wed 5/276:00 am
SDF
- SYR
2 stops8h 15m
United Airlines
Deal found 5/8![United Airlines logo]()
$360
This United Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/225:49 pm
SYR
- SDF
1 stop6h 00m
United Airlines
Mon 5/256:00 am
SDF
- SYR
1 stop4h 48m
United Airlines
Deal found 5/11![United Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/37:34 pm
SYR
- SDF
1 stop5h 00m
American Airlines
Sat 8/156:17 pm
SDF
- SYR
1 stop5h 28m
American Airlines
Deal found 5/11![American Airlines logo]()
$374
This United Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:00 am
SYR
- SDF
2 stops7h 35m
United Airlines
Sun 5/316:00 am
SDF
- SYR
1 stop4h 48m
United Airlines
Deal found 5/9![United Airlines logo]()
$375
Best flights from Syracuse to LouisvilleDiscover carefully curated flight deals from Syracuse to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 13, 2026.
Discover carefully curated flight deals from Syracuse to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 13, 2026.
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:00 am
SYR
- SDF
1 stop4h 58m
Delta
Wed 6/176:34 pm
SDF
- SYR
1 stop5h 25m
Delta
Deal found 5/9![Delta logo]()
$299
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:07 pm
SYR
- SDF
1 stop4h 57m
American Airlines
Fri 6/126:25 pm
SDF
- SYR
1 stop5h 22m
American Airlines
Deal found 5/7![American Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:00 am
SYR
- SDF
2 stops10h 38m
United Airlines
Thu 9/35:15 am
SDF
- SYR
2 stops8h 59m
United Airlines
Deal found 5/12![United Airlines logo]()
$533
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:05 am
SYR
- SDF
1 stop5h 48m
Delta
Tue 6/306:00 am
SDF
- SYR
1 stop5h 42m
Delta
Deal found 5/9![Delta logo]()
$309
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/266:00 am
SYR
- SDF
1 stop7h 32m
Delta
Tue 6/306:34 pm
SDF
- SYR
1 stop5h 25m
Delta
Deal found 5/11![Delta logo]()
$309
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/176:00 am
SYR
- SDF
1 stop4h 29m
Delta
Fri 7/246:45 pm
SDF
- SYR
1 stop5h 13m
Delta
Deal found 5/10![Delta logo]()
$319
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:00 am
SYR
- SDF
1 stop6h 10m
Delta
Mon 6/15:52 pm
SDF
- SYR
1 stop5h 57m
Delta
Deal found 5/9![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1010:18 am
SYR
- SDF
2 stops7h 41m
American Airlines
Mon 8/172:36 pm
SDF
- SYR
1 stop7h 18m
American Airlines
Deal found 5/12![American Airlines logo]()
$531
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/276:11 am
SYR
- SDF
1 stop3h 44m
Delta
Mon 6/294:40 pm
SDF
- SYR
1 stop7h 19m
Delta
Deal found 5/11![Delta logo]()
$379
This Delta deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/183:11 pm
SYR
- SDF
1 stop7h 25m
Delta
Sun 9/206:05 am
SDF
- SYR
1 stop5h 04m
Delta
Deal found 5/12![Delta logo]()
$439
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:05 am
SYR
- SDF
1 stop5h 48m
Delta
Sun 6/281:02 pm
SDF
- SYR
2 stops11h 41m
Delta
Deal found 5/9![Delta logo]()
$482
Last-minute flights from Syracuse to LouisvilleDiscover last-minute flight deals from Syracuse to Louisville. Data last updated May 13, 2026 and is based on user searches.
Discover last-minute flight deals from Syracuse to Louisville. Data last updated May 13, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/225:49 pm
SYR
- SDF
1 stop6h 00m
United Airlines
Mon 5/256:00 am
SDF
- SYR
1 stop4h 48m
United Airlines
Deal found 5/11![United Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:49 pm
SYR
- SDF
1 stop6h 00m
United Airlines
Wed 5/276:00 am
SDF
- SYR
2 stops8h 15m
United Airlines
Deal found 5/8![United Airlines logo]()
$360
This United Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:00 am
SYR
- SDF
2 stops7h 35m
United Airlines
Sun 5/316:00 am
SDF
- SYR
1 stop4h 48m
United Airlines
Deal found 5/9![United Airlines logo]()
$375
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/611:15 am
SYR
- SDF
2 stops7h 22m
American Airlines
Fri 6/127:18 pm
SDF
- SYR
1 stop4h 41m
American Airlines
Deal found 5/11![American Airlines logo]()
$400
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:11 am
SYR
- SDF
1 stop3h 44m
Delta
Tue 6/306:34 pm
SDF
- SYR
1 stop5h 25m
Delta
Deal found 5/11![Delta logo]()
$309
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:05 am
SYR
- SDF
1 stop5h 48m
Delta
Fri 7/35:26 pm
SDF
- SYR
1 stop5h 31m
Delta
Deal found 5/11![Delta logo]()
$319
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:05 am
SYR
- SDF
1 stop5h 48m
Delta
Thu 7/25:26 pm
SDF
- SYR
1 stop5h 31m
Delta
Deal found 5/11![Delta logo]()
$399
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/276:11 am
SYR
- SDF
1 stop3h 44m
Delta
Sat 7/47:55 am
SDF
- SYR
1 stop4h 34m
Delta
Deal found 5/11![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/276:11 am
SYR
- SDF
1 stop3h 44m
Delta
Fri 7/35:26 pm
SDF
- SYR
1 stop5h 31m
Delta
Deal found 5/11![Delta logo]()
$349
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/276:11 am
SYR
- SDF
1 stop3h 44m
Delta
Mon 6/294:40 pm
SDF
- SYR
1 stop7h 19m
Delta
Deal found 5/11![Delta logo]()
$379
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/286:00 am
SYR
- SDF
1 stop7h 32m
Delta
Sat 7/45:26 pm
SDF
- SYR
1 stop5h 31m
Delta
Deal found 5/11![Delta logo]()
$389
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:11 am
SYR
- SDF
1 stop3h 44m
Delta
Sat 7/47:55 am
SDF
- SYR
1 stop4h 34m
Delta
Deal found 5/11![Delta logo]()
$299
One-way flights from Syracuse to LouisvilleSearch for one-way flight options from Syracuse to Louisville. Find affordable one-way fares based on user searches. Data last updated May 13, 2026.
Search for one-way flight options from Syracuse to Louisville. Find affordable one-way fares based on user searches. Data last updated May 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/1910:38 am
SYR
- SDF
1 stop27h 29m
Allegiant Air
Deal found 5/10![Allegiant Air logo]()
$198
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/197:26 pm
SYR
- SDF
2 stops18h 41m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$255
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/56:11 am
SYR
- SDF
1 stop3h 44m
Delta
Deal found 5/11![Delta logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/57:26 pm
SYR
- SDF
2 stops18h 41m
Multiple Airlines
Deal found 5/11![Multiple Airlines logo]()
$342
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2410:36 am
SYR
- SDF
1 stop27h 25m
Allegiant Air
Deal found 5/9![Allegiant Air logo]()
$344
This American Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/242:00 pm
SYR
- SDF
2 stops7h 41m
American Airlines
Deal found 5/9![American Airlines logo]()
$369
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/52:36 pm
SYR
- SDF
3 stops23h 31m
Allegiant Air
Deal found 5/11![Allegiant Air logo]()
$490
Find flight deals from Syracuse to Louisville
Discover tips and strategies to find the most affordable flight options for your journey from Syracuse (SYR) to Louisville (SDF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $299 (Delta) |
One-way from | $198 (Kiwi.com) |
Popular in | April |
Cheapest in | August |
Average price | $311 |
Cheapflights Fare Finder
Customize your flight search to find flights from Syracuse to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 13, 2026.
Use the filters below to find and compare flights from Syracuse to Louisville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
SyracuseLouisville
SYR - SDF
SYRSDF
Syracuse Hancock Intl
Wed 6/10
6:00 am-10:58 am
1 stop4h 58m
Louisville Intl
Wed 6/17
6:34 pm-11:59 pm
1 stop5h 25m
$299
SyracuseLouisville
SYR - SDF
SYRSDF
Syracuse Hancock Intl
Sat 6/6
5:07 pm-10:04 pm
1 stop4h 57m
Louisville Intl
Fri 6/12
6:25 pm-11:47 pm
1 stop5h 22m
$309
SyracuseLouisville
SYR - SDF
SYRSDF
Syracuse Hancock Intl
Thu 6/25
6:05 am-11:53 am
1 stop5h 48m
Louisville Intl
Tue 6/30
6:00 am-11:42 am
1 stop5h 42m
$309
SyracuseLouisville
SYR - SDF
SYRSDF
Syracuse Hancock Intl
Fri 6/26
6:00 am-1:32 pm
1 stop7h 32m
Louisville Intl
Tue 6/30
6:34 pm-11:59 pm
1 stop5h 25m
$309
Quickest round-trip
SyracuseLouisville
SYR - SDF
SYRSDF
Syracuse Hancock Intl
Fri 7/17
6:00 am-10:29 am
1 stop4h 29m
Louisville Intl
Fri 7/24
6:45 pm-11:58 pm
1 stop5h 13m
$319
SyracuseLouisville
SYR - SDF
SYRSDF
Syracuse Hancock Intl
Wed 5/27
6:00 am-12:10 pm
1 stop6h 10m
Louisville Intl
Mon 6/1
5:52 pm-11:49 pm
1 stop5h 57m
$339
SyracuseLouisville
SYR - SDF
SYRSDF
Syracuse Hancock Intl
Sat 6/27
6:11 am-9:55 am
1 stop3h 44m
Louisville Intl
Mon 6/29
4:40 pm-11:59 pm
1 stop7h 19m
$379
SyracuseLouisville
SYR - SDF
SYRSDF
Syracuse Hancock Intl
Fri 9/18
3:11 pm-10:36 pm
1 stop7h 25m
Louisville Intl
Sun 9/20
6:05 am-11:09 am
1 stop5h 04m
$439
SyracuseLouisville
SYR - SDF
SYRSDF
Syracuse Hancock Intl
Thu 6/25
6:05 am-11:53 am
1 stop5h 48m
Louisville Intl
Sun 6/28
1:02 pm-12:43 am
2 stops11h 41m
$482
SyracuseLouisville
SYR - SDF
SYRSDF
Syracuse Hancock Intl
Mon 8/10
10:18 am-5:59 pm
2 stops7h 41m
Louisville Intl
Mon 8/17
2:36 pm-9:54 pm
1 stop7h 18m
$531
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Syracuse to Louisville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Syracuse to Louisville in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Syracuse-Louisville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Syracuse-Louisville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Syracuse-Louisville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Syracuse-Louisville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Syracuse-Louisville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Syracuse to Louisville
Have a flexible travel schedule? Discover the best time to fly to Louisville from Syracuse with our price prediction graph.
SYR-SDF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Syracuse to Louisville
What is the cheapest month to book a flight from Syracuse to Louisville?
Currently, August is the cheapest month in which you can book a flight from Syracuse to Louisville (average of $248). Flying from Syracuse to Louisville in April is currently the most expensive (average of $653). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Syracuse to Louisville?
Reviews of airlines servicing Louisville
Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated May 13, 2026.
Peruse reviews from past customers who have flown with Delta and American Airlines from Syracuse to Louisville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Overall
7.9
Entertainment
7.8
Food
7.2
Crew
8.5
Boarding
8.1
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Comfort
7.8
Overall
7.9
Entertainment
7.8
Food
7.2
Crew
8.5
Boarding
8.1
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Comfort
7.8
Overall
7.9
Entertainment
7.8
Food
7.2
Crew
8.5
Boarding
8.1
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Related info for your journey
Find useful and relevant information for your journey from Syracuse to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Louisville?
Book flights to Louisville if you plan to visit one of these locationsShepherdsville
Elizabethtown
Corydon
Jeffersonville
Bardstown
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Louisville flight routes
Other flight options
Other flights from Syracuse
Popular flights
Alternative routes for Syracuse to Louisville
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Louisville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Syracuse to Louisville by cabin class
Find flights from Syracuse to Louisville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Louisville
Explore flights to Louisville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 13, 2026.
Syracuse and Louisville flights
Browse other Syracuse and Louisville flight options. Last updated on May 13, 2026.
Other flights from Syracuse
Browse through other flights departing from Syracuse. Flights are based on user searches made on Cheapflights and were last updated on May 13, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Syracuse to Louisville
Discover the top 2 airlines that operate flights from Syracuse to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$193 | Average$386 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$248 | Average$363 | FlexibilityNo cancel fee | On-time71% |