HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Louisville

$182+ Cheap flights from Syracuse to Louisville (SYR - SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/23. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — SDF
Apr 9 — Apr 161
Thu 4/9
Thu 4/16
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Syracuse to Louisville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Syracuse to Louisville

Cheapest flights from Syracuse to Louisville
Explore the most affordable flight options available from Syracuse to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.

This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/265:40 am
SYR
-
SDF
1 stop5h 06m
American Airlines
Tue 5/58:03 am
SDF
-
SYR
1 stop6h 01m
American Airlines
Deal found 3/6$289
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/275:47 pm
SYR
-
SDF
1 stop4h 43m
United Airlines
Wed 5/67:15 am
SDF
-
SYR
2 stops6h 59m
United Airlines
Deal found 3/6$294
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/216:25 am
SYR
-
SDF
1 stop6h 52m
United Airlines
Wed 3/251:58 pm
SDF
-
SYR
1 stop6h 44m
United Airlines
Deal found 3/6$299
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/176:18 am
SYR
-
SDF
1 stop6h 38m
Delta
Thu 7/236:05 am
SDF
-
SYR
1 stop5h 04m
Delta
Deal found 3/5$311
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:18 am
SYR
-
SDF
1 stop6h 43m
Delta
Sun 10/116:05 am
SDF
-
SYR
1 stop5h 04m
Delta
Deal found 3/8$314
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/266:15 am
SYR
-
SDF
2 stops10h 26m
United Airlines
Tue 5/55:54 am
SDF
-
SYR
1 stop3h 45m
United Airlines
Deal found 3/6$324
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:00 am
SYR
-
SDF
2 stops7h 01m
United Airlines
Sat 9/127:22 am
SDF
-
SYR
2 stops6h 47m
United Airlines
Deal found 3/5$327
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:00 am
SYR
-
SDF
2 stops7h 17m
United Airlines
Sat 3/285:35 am
SDF
-
SYR
1 stop4h 20m
United Airlines
Deal found 3/9$334
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/196:18 am
SYR
-
SDF
1 stop4h 37m
Delta
Sat 7/256:26 pm
SDF
-
SYR
1 stop4h 30m
Delta
Deal found 3/5$335
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/275:47 pm
SYR
-
SDF
1 stop4h 43m
United Airlines
Mon 5/45:54 am
SDF
-
SYR
1 stop3h 45m
United Airlines
Deal found 3/10$344
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/55:45 pm
SYR
-
SDF
1 stop4h 45m
United Airlines
Sat 5/93:36 pm
SDF
-
SYR
2 stops7h 54m
United Airlines
Deal found 3/5$364

Find flight deals from Syracuse to Louisville

Discover tips and strategies to find the most affordable flight options for your journey from Syracuse (SYR) to Louisville (SDF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 10, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$289
(American Airlines)

One-way from

$182
(Kiwi.com)

Popular in

September

Cheapest in

August

Average price

$384
Provider with most accurate pricing for Syracuse Hancock Intl-Louisville Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Syracuse Hancock Intl-Louisville Intl flights.
Search Deals
From Syracuse Hancock Intl to Louisville Intl
Search Deals
One-way flight from Syracuse Hancock Intl to Louisville Intl
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($14 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Syracuse to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
Use the filters below to find and compare flights from Syracuse to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Sun 4/26

5:40 am-10:46 am

1 stop5h 06m

Louisville Intl

Tue 5/5

6:00 am-11:00 am

1 stop5h 00m

$289

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Mon 4/27

5:13 pm-9:20 pm

1 stop4h 07m

Louisville Intl

Wed 5/6

11:27 am-4:50 pm

1 stop5h 23m

$289

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Sat 3/21

6:25 am-1:17 pm

1 stop6h 52m

Louisville Intl

Wed 3/25

1:58 pm-8:42 pm

1 stop6h 44m

$299

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Tue 5/5

10:35 am-10:30 pm

2 stops11h 55m

Louisville Intl

Sat 5/9

9:10 am-1:25 pm

1 stop4h 15m

$364

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Sun 4/26

5:47 pm-11:59 pm

1 stop6h 12m

Louisville Intl

Tue 5/5

2:55 pm-11:30 pm

2 stops8h 35m

$367

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Fri 4/17

6:00 am-4:41 pm

2 stops10h 41m

Louisville Intl

Sun 4/19

5:00 am-9:40 am

1 stop4h 40m

$382

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Fri 4/17

6:30 am-1:31 pm

1 stop7h 01m

Louisville Intl

Mon 4/20

6:08 pm-11:10 pm

1 stop5h 02m

$394
Quickest round-trip

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Fri 3/20

5:29 pm-10:13 pm

1 stop4h 44m

Louisville Intl

Tue 3/24

9:55 am-2:08 pm

1 stop4h 13m

$399
Cheapest one-way

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Mon 3/23

11:37 am-11:47 am

1 stop24h 10m

$182

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Sun 3/22

9:22 pm-11:47 am

2 stops38h 25m

$230

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/8

Showing 1-10 of 17 resultsSorted by cheapest first
1
2

Compare providers for flights from Syracuse to Louisville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Syracuse to Louisville in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Syracuse-Louisville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Syracuse-Louisville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Syracuse-Louisville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Syracuse-Louisville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Syracuse-Louisville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Syracuse to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Louisville

What is the cheapest month to book a flight from Syracuse to Louisville?

Currently, April is the cheapest month in which you can book a flight from Syracuse to Louisville (average of $108). Flying from Syracuse to Louisville in March is currently the most expensive (average of $249). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Louisville

Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated March 10, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from Syracuse to Louisville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,276 reviews

Overall

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.8

Food

7.2

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
7.9
Good
8,276 reviews
Delta
7.9
Good
8,276 reviews

Overall

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.8

Food

7.2

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
9,409 reviews
Delta
7.9
Good
8,276 reviews

Overall

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.8

Food

7.2

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.1
Good
11,413 reviews
Delta
7.9
Good
8,276 reviews

Overall

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.8

Food

7.2

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Syracuse to Louisville?

    A quick flight from Syracuse to Louisville can take about 4h 07m. American Airlines provides one of the quickest options available for as low as $289. The distance between Syracuse and Louisville is about 608 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Syracuse to Louisville round-trip?

    According to our current data, Delta ($194), American Airlines ($248), and United Airlines ($271) offers the cheapest pricing from Syracuse to Louisville. Users have found that Delta is 45% cheaper than the other options available to this destination.

  • Can I find deals for flights from Syracuse to Louisville that include hotel bookings?

    Yes. In addition to deals on Syracuse to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Louisville.

  • Can I find deals for business class flights from Syracuse to Louisville?

    Yes. Cheapflights offers flight deals from Syracuse to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to Louisville?

    Currently, April is the cheapest month in which you can book a flight from Syracuse to Louisville (average of $108). Flying from Syracuse to Louisville in March is currently the most expensive (average of $249). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Jeffersonville
Elizabethtown
Corydon
Bardstown

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Syracuse to Louisville

See prices for flight routes from nearby airports that may be better suited for you.
Newark to Nashville flights
John F Kennedy Intl to Nashville flights
LaGuardia to Nashville flights
LaGuardia to Cincinnati flights
John F Kennedy Intl to Cincinnati flights
Newark to Cincinnati flights
LaGuardia to Knoxville flights
LaGuardia to Louisville flights
Newark to Louisville flights
John F Kennedy Intl to Knoxville flights
John F Kennedy Intl to Louisville flights
Albany to Nashville flights
Buffalo to Nashville flights
Newark to Knoxville flights
LaGuardia to Lexington flights
Newark to Lexington flights
Syracuse to Nashville flights
John F Kennedy Intl to Lexington flights
Stewart to Nashville flights
White Plains to Nashville flights
Stewart to Cincinnati flights
Syracuse to Knoxville flights
Rochester to Nashville flights
Syracuse to Cincinnati flights
Albany to Knoxville flights
Rochester to Knoxville flights
Rochester to Louisville flights
Stewart to Louisville flights
Islip to Nashville flights
Buffalo to Knoxville flights
White Plains to Cincinnati flights
Albany to Louisville flights
Newark to Blountville flights
Rochester to Lexington flights
Syracuse to Lexington flights
White Plains to Knoxville flights
White Plains to Louisville flights
Buffalo to Lexington flights
John F Kennedy Intl to Blountville flights
Albany to Lexington flights
Buffalo to Louisville flights
LaGuardia to Blountville flights
Albany to Cincinnati flights
Ithaca to Nashville flights
Buffalo to Cincinnati flights
Rochester to Cincinnati flights
Islip to Knoxville flights

Top 3 airlines flying from Syracuse to Louisville

Discover the top 3 airlines that operate flights from Syracuse to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$194Average$339FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$308FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$271Average$344FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.