$203+ Cheap flights from Syracuse to Louisville (SYR - SDF)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/5. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — SDF
Nov 6 — Nov 131
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Syracuse to Louisville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Syracuse to Louisville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Syracuse to LouisvilleExplore the most affordable flight options available from Syracuse to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 7, 2026.
Explore the most affordable flight options available from Syracuse to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 7, 2026.
This Delta deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am -
1 stop5h 56m
Sun 11/155:40 pm -
1 stop5h 14m
Deal found 10/5![Delta logo]()
$334
This Delta deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:09 am -
1 stop7h 50m
Sun 11/17:55 am -
1 stop4h 17m
Deal found 10/5![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/272:55 pm -
1 stop4h 35m
Sun 11/15:10 am -
2 stops9h 02m
Deal found 10/5![United Airlines logo]()
$344
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:07 am -
1 stop7h 08m
Sun 10/256:00 am -
1 stop3h 42m
Deal found 10/5![United Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:00 am -
2 stops11h 40m
Tue 10/2010:00 am -
1 stop4h 19m
Deal found 10/2![United Airlines logo]()
$374
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2211:57 am -
1 stop5h 26m
Sun 10/256:00 am -
1 stop5h 27m
Deal found 10/4![American Airlines logo]()
$394
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1610:29 am -
1 stop4h 10m
Mon 10/1910:00 am -
1 stop4h 19m
Deal found 10/4![United Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2812:12 pm -
1 stop4h 48m
Thu 12/35:59 pm -
1 stop5h 53m
Deal found 10/7![Delta logo]()
$409
Best flights from Syracuse to LouisvilleDiscover carefully curated flight deals from Syracuse to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 7, 2026.
Discover carefully curated flight deals from Syracuse to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 7, 2026.
This Delta deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:07 am -
1 stop7h 56m
Tue 11/171:01 pm -
1 stop5h 02m
Deal found 10/3![Delta logo]()
$334
This United Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/135:40 am -
1 stop4h 54m
Tue 11/172:10 pm -
2 stops9h 33m
Deal found 10/3![United Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2211:57 am -
1 stop5h 26m
Sun 10/256:00 am -
1 stop5h 27m
Deal found 10/4![American Airlines logo]()
$394
This Delta deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am -
1 stop5h 56m
Sun 11/155:40 pm -
1 stop5h 14m
Deal found 10/5![Delta logo]()
$334
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/272:55 pm -
1 stop4h 35m
Sun 11/15:10 am -
2 stops9h 02m
Deal found 10/5![United Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:22 am -
1 stop3h 37m
Sun 11/86:00 am -
1 stop5h 06m
Deal found 10/5![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:17 am -
2 stops12h 13m
Sun 11/155:10 am -
1 stop5h 35m
Deal found 10/7![United Airlines logo]()
$439
Last-minute flights from Syracuse to LouisvilleDiscover last-minute flight deals from Syracuse to Louisville. Data last updated October 7, 2026 and is based on user searches.
Discover last-minute flight deals from Syracuse to Louisville. Data last updated October 7, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1610:29 am -
1 stop4h 10m
Mon 10/1910:00 am -
1 stop4h 19m
Deal found 10/4![United Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:00 am -
2 stops11h 40m
Tue 10/2010:00 am -
1 stop4h 19m
Deal found 10/2![United Airlines logo]()
$374
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:07 am -
1 stop7h 08m
Sun 10/256:00 am -
1 stop3h 42m
Deal found 10/5![United Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2211:57 am -
1 stop5h 26m
Sun 10/256:00 am -
1 stop5h 27m
Deal found 10/4![American Airlines logo]()
$394
This Delta deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:09 am -
1 stop7h 50m
Sun 11/17:55 am -
1 stop4h 17m
Deal found 10/5![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/272:55 pm -
1 stop4h 35m
Sun 11/15:10 am -
2 stops9h 02m
Deal found 10/5![United Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am -
1 stop5h 56m
Sun 11/155:40 pm -
1 stop5h 14m
Deal found 10/5![Delta logo]()
$334
This Delta deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2812:12 pm -
1 stop4h 48m
Thu 12/35:59 pm -
1 stop5h 53m
Deal found 10/7![Delta logo]()
$409
One-way flights from Syracuse to LouisvilleSearch for one-way flight options from Syracuse to Louisville. Find affordable one-way fares based on user searches. Data last updated October 7, 2026.
Search for one-way flight options from Syracuse to Louisville. Find affordable one-way fares based on user searches. Data last updated October 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/512:02 pm -
1 stop8h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/4![Breeze Airways logo]()
$203
This Kiwi.com deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:31 pm -
2 stops40h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![Multiple Airlines logo]()
$233
This Kiwi.com deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:21 pm -
3 stops36h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![Breeze Airways logo]()
$336
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/52:10 pm -
2 stops8h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/4![American Airlines logo]()
$355
This Delta deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/261:41 pm -
1 stop3h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![Delta logo]()
$369
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/52:15 pm -
3 stops24h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/4![United Airlines logo]()
$446
Find flight deals from Syracuse to Louisville
Discover tips and strategies to find the most affordable flight options for your journey from Syracuse (SYR) to Louisville (SDF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $334 (Delta) |
One-way from | $203 (Kiwi.com) |
Popular in | April |
Cheapest in | February |
Average price | $488 |
Cheapflights Fare Finder
Customize your flight search to find flights from Syracuse to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 7, 2026.
Use the filters below to find and compare flights from Syracuse to Louisville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
SyracuseLouisville
SYR Syracuse Hancock Intl - SDF Louisville Intl
SYRSDF
Syracuse Hancock Intl
Sat 12/5
12:02 pm-8:47 pm
1 stop8h 45m
Louisville Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$203
SyracuseLouisville
SYR Syracuse Hancock Intl - SDF Louisville Intl
SYRSDF
Syracuse Hancock Intl
Mon 10/26
5:31 pm-10:11 am
2 stops40h 40m
Louisville Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$233
SyracuseLouisville
SYR Syracuse Hancock Intl - SDF Louisville Intl
SYRSDF
Syracuse Hancock Intl
Fri 11/13
6:07 am-2:03 pm
1 stop7h 56m
Louisville Intl
Tue 11/17
1:01 pm-6:03 pm
1 stop5h 02m
$334
SyracuseLouisville
SYR Syracuse Hancock Intl - SDF Louisville Intl
SYRSDF
Syracuse Hancock Intl
Wed 11/11
6:00 am-11:56 am
1 stop5h 56m
Louisville Intl
Sun 11/15
5:40 pm-10:54 pm
1 stop5h 14m
$334
SyracuseLouisville
SYR Syracuse Hancock Intl - SDF Louisville Intl
SYRSDF
Syracuse Hancock Intl
Fri 11/13
5:40 am-10:34 am
1 stop4h 54m
Louisville Intl
Tue 11/17
2:10 pm-11:43 pm
2 stops9h 33m
$339
SyracuseLouisville
SYR Syracuse Hancock Intl - SDF Louisville Intl
SYRSDF
Syracuse Hancock Intl
Fri 11/6
6:22 am-9:59 am
1 stop3h 37m
Louisville Intl
Sun 11/8
6:00 am-11:06 am
1 stop5h 06m
$339
SyracuseLouisville
SYR Syracuse Hancock Intl - SDF Louisville Intl
SYRSDF
Syracuse Hancock Intl
Tue 10/27
2:55 pm-7:30 pm
1 stop4h 35m
Louisville Intl
Sun 11/1
5:10 am-2:12 pm
2 stops9h 02m
$344
SyracuseLouisville
SYR Syracuse Hancock Intl - SDF Louisville Intl
SYRSDF
Syracuse Hancock Intl
Sat 12/5
2:10 pm-10:59 pm
2 stops8h 49m
Louisville Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$355
Quickest round-trip
SyracuseLouisville
SYR Syracuse Hancock Intl - SDF Louisville Intl
SYRSDF
Syracuse Hancock Intl
Mon 10/26
1:41 pm-5:18 pm
1 stop3h 37m
Louisville Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$369
SyracuseLouisville
SYR Syracuse Hancock Intl - SDF Louisville Intl
SYRSDF
Syracuse Hancock Intl
Thu 10/22
11:57 am-5:23 pm
1 stop5h 26m
Louisville Intl
Sun 10/25
6:00 am-11:27 am
1 stop5h 27m
$394
Showing 1-10 of 12 resultsSorted by cheapest first
Compare providers for flights from Syracuse to Louisville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Syracuse to Louisville in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Syracuse-Louisville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Syracuse-Louisville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Syracuse-Louisville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Syracuse-Louisville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Syracuse-Louisville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Syracuse to Louisville
Have a flexible travel schedule? Discover the best time to fly to Louisville from Syracuse with our price prediction graph.
SYR-SDF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Syracuse to Louisville
What is the cheapest month to book a flight from Syracuse to Louisville?
Currently, February is the cheapest month in which you can book a flight from Syracuse to Louisville (average of $288). Flying from Syracuse to Louisville in April is currently the most expensive (average of $653). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Syracuse to Louisville?
Airfare is below average for this route at the moment.
Syracuse to Louisville flights typically cost between $433 and $600 in November.The cheapest round-trip price found within the last 5 days was $334 on Delta (Nov 11-Nov 15).
Reviews of airlines servicing Louisville
Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated October 7, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from Syracuse to Louisville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Crew
8.5
Boarding
8.1
Comfort
7.8
Overall
7.8
Food
7.2
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Entertainment
7.8
Crew
8.5
Boarding
8.1
Comfort
7.8
Overall
7.8
Food
7.2
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Entertainment
7.8
Crew
8.5
Boarding
8.1
Comfort
7.8
Overall
7.8
Food
7.2
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Entertainment
7.8
Crew
8.5
Boarding
8.1
Comfort
7.8
Overall
7.8
Food
7.2
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Related info for your journey
Find useful and relevant information for your journey from Syracuse to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Louisville?
Book flights to Louisville if you plan to visit one of these locationsShepherdsville
Elizabethtown
Jeffersonville
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Louisville flight routes
Other flight options
Other flights from Syracuse
Popular flights
Alternative routes for Syracuse to Louisville
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Louisville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Syracuse to Louisville by cabin class
Find flights from Syracuse to Louisville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Louisville
Explore flights to Louisville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 7, 2026.
Syracuse and Louisville flights
Browse other Syracuse and Louisville flight options. Last updated on October 7, 2026.
Other flights from Syracuse
Browse through other flights departing from Syracuse. Flights are based on user searches made on Cheapflights and were last updated on October 7, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Syracuse to Louisville
Discover the top 3 airlines that operate flights from Syracuse to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$193 | Average$393 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$248 | Average$400 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$308 | Average$383 | FlexibilityNo cancel fee | On-time69% |