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$119+ Cheap flights from Syracuse to Louisville (SYR - SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/18. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — SDF
Aug 19 — Aug 261
Tue 8/19
Tue 8/26
1 adult, Economy
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Cheap flight deals from Syracuse to Louisville

Discover tips and strategies to find the most affordable flight options for your journey from Syracuse (SYR) to Louisville (SDF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 14, 2025.

Round-trip from

$249
(American Airlines)

One-way from

$119
(Kiwi.com)

Popular in

September

Cheapest in

August

Average price

$248
From Syracuse Hancock Intl to Louisville Intl
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One-way flight from Syracuse Hancock Intl to Louisville Intl
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Highest demand for flights based on searches. 8% potential increase in price ($34 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($20 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Syracuse to Louisville

Cheapest flights from Syracuse to Louisville
Explore the most affordable flight options available from Syracuse to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/106:10 amSYR - SDF
1 stop4h 16mAmerican Airlines
Sun 9/147:35 amSDF - SYR
1 stop4h 58mAmerican Airlines
Deal found 8/12$249
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/306:00 amSYR - SDF
1 stop4h 05mAmerican Airlines
Sun 8/316:44 amSDF - SYR
1 stop4h 56mAmerican Airlines
Deal found 8/14$259
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/294:45 pmSYR - SDF
1 stop6h 18mAmerican Airlines
Sun 11/27:31 pmSDF - SYR
1 stop4h 48mAmerican Airlines
Deal found 8/14$274
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/255:43 pmSYR - SDF
1 stop4h 47mUnited Airlines
Tue 10/282:02 pmSDF - SYR
1 stop7h 00mUnited Airlines
Deal found 8/14$319
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/116:00 amSYR - SDF
1 stop4h 43mAmerican Airlines
Sun 10/125:53 pmSDF - SYR
1 stop5h 36mAmerican Airlines
Deal found 8/13$347
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/105:32 amSYR - SDF
1 stop5h 09mAmerican Airlines
Mon 9/156:30 pmSDF - SYR
1 stop4h 24mAmerican Airlines
Deal found 8/13$367
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/303:01 pmSYR - SDF
2 stops7h 23mUnited Airlines
Sun 8/311:59 pmSDF - SYR
1 stop7h 06mUnited Airlines
Deal found 8/14$374
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/166:44 pmSYR - SDF
1 stop5h 08mDelta
Fri 9/197:33 pmSDF - SYR
1 stop4h 26mDelta
Deal found 8/13$379
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1611:03 amSYR - SDF
2 stops9h 59mUnited Airlines
Fri 9/197:36 pmSDF - SYR
1 stop21h 10mUnited Airlines
Deal found 8/14$404
This Mytrip deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/3012:52 pmSYR - SDF
2 stops23h 00mMultiple Airlines
Sun 8/312:46 pmSDF - SYR
2 stops18h 54mMultiple Airlines
Deal found 8/14$410

Cheapflights Fare Finder

 
Customize your flight search to find flights from Syracuse to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
Use the filters below to find and compare flights from Syracuse to Louisville that are best for you.

Fly from

Syracuse

Fly to

Louisville

Route

Depart

Return

Price

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Wed 9/10

6:10 am-10:26 am

1 stop4h 16m

Louisville Intl

Sun 9/14

7:35 am-12:33 pm

1 stop4h 58m

$249

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Sat 8/30

6:00 am-10:05 am

1 stop4h 05m

Louisville Intl

Sun 8/31

6:44 am-11:40 am

1 stop4h 56m

$259

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Wed 10/29

4:45 pm-11:03 pm

1 stop6h 18m

Louisville Intl

Sun 11/2

7:31 pm-12:19 am

1 stop4h 48m

$274

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Sat 10/25

5:43 pm-10:30 pm

1 stop4h 47m

Louisville Intl

Tue 10/28

2:02 pm-9:02 pm

1 stop7h 00m

$319

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Sat 10/11

6:00 am-10:43 am

1 stop4h 43m

Louisville Intl

Sun 10/12

5:53 pm-11:29 pm

1 stop5h 36m

$347

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Wed 9/10

5:32 am-10:41 am

1 stop5h 09m

Louisville Intl

Mon 9/15

6:30 pm-10:54 pm

1 stop4h 24m

$367

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Sat 8/30

3:01 pm-10:24 pm

2 stops7h 23m

Louisville Intl

Sun 8/31

1:59 pm-9:05 pm

1 stop7h 06m

$374

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Tue 9/16

7:40 am-5:38 pm

1 stop9h 58m

Louisville Intl

Fri 9/19

7:00 am-8:01 pm

1 stop13h 01m

$377

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Thu 9/11

5:28 pm-11:01 pm

1 stop5h 33m

Louisville Intl

Mon 9/15

6:30 pm-10:54 pm

1 stop4h 24m

$377

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Thu 9/18

7:28 pm-8:57 am

1 stop13h 29m

$119

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/14

Showing 1-10 of 13 results
1
2

Best time to book a flight from Syracuse to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Louisville

What is the cheapest month to book a flight from Syracuse to Louisville?

Currently, January is the cheapest month in which you can book a flight from Syracuse to Louisville (average of $299). Flying from Syracuse to Louisville in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SYR to SDF?

Find hourly flight availability from Syracuse to Louisville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 14, 2025.

When flying from Syracuse to Louisville, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 23% versus a flight in the afternoon.

Reviews of airlines servicing Louisville

Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated August 14, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Syracuse to Louisville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,980 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
8.0
Very good
7,980 reviews
Delta
8.0
Very good
7,980 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
8,916 reviews
Delta
8.0
Very good
7,980 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,980 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Syracuse to Louisville round-trip?

    According to our current data, Delta ($232), American Airlines ($248), and United Airlines ($271) offers the cheapest pricing from Syracuse to Louisville. Users have found that Delta is 36% cheaper than the other options available to this destination.

  • Can I find deals for flights from Syracuse to Louisville that include hotel bookings?

    Yes. In addition to deals on Syracuse to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Louisville.

  • Can I find deals for business class flights from Syracuse to Louisville?

    Yes. Cheapflights offers flight deals from Syracuse to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to Louisville?

    Currently, January is the cheapest month in which you can book a flight from Syracuse to Louisville (average of $299). Flying from Syracuse to Louisville in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Jeffersonville
Elizabethtown
Corydon
Bardstown

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Syracuse to Louisville

Discover the top 3 airlines that operate flights from Syracuse to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$232Average$329FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$368FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$271Average$438FlexibilityNo cancel feeOn-time69%

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