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$249+ Cheap flights from Syracuse to Louisville (SYR - SDF)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/14. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — SDF
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Syracuse to Louisville

Discover tips and strategies to find the most affordable flight options for your journey from Syracuse (SYR) to Louisville (SDF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2025.

Round-trip from

$249
(Delta)

Popular in

September

Cheapest in

August

Average price

$578
From Syracuse Hancock Intl to Louisville Intl
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($55 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
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Find flight deals from Syracuse to Louisville

Cheapest flights from Syracuse to Louisville
Explore the most affordable flight options available from Syracuse to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/146:39 pmSYR - SDF
1 stop5h 22mDelta
Tue 10/2110:15 amSDF - SYR
1 stop6h 45mDelta
Deal found 9/15$249
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/306:15 amSYR - SDF
1 stop6h 35mDelta
Sat 10/45:56 pmSDF - SYR
1 stop6h 03mDelta
Deal found 9/15$259
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/3010:28 amSYR - SDF
1 stop4h 23mUnited Airlines
Sat 10/41:58 pmSDF - SYR
2 stops9h 44mUnited Airlines
Deal found 9/15$264
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/235:45 pmSYR - SDF
1 stop3h 31mDelta
Tue 10/216:00 amSDF - SYR
1 stop5h 37mDelta
Deal found 9/15$279
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/257:38 pmSYR - SDF
1 stop4h 21mAmerican Airlines
Thu 10/211:15 amSDF - SYR
1 stop5h 54mAmerican Airlines
Deal found 9/15$284
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2612:39 pmSYR - SDF
1 stop7h 54mUnited Airlines
Tue 9/301:58 pmSDF - SYR
2 stops9h 17mUnited Airlines
Deal found 9/15$289
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/137:46 pmSYR - SDF
1 stop13h 18mMultiple Airlines
Sun 11/168:53 pmSDF - SYR
2 stops14h 15mMultiple Airlines
Deal found 9/15$291
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/206:00 amSYR - SDF
1 stop3h 46mDelta
Tue 10/216:00 amSDF - SYR
1 stop5h 37mDelta
Deal found 9/15$294
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2512:39 pmSYR - SDF
1 stop5h 54mUnited Airlines
Thu 10/27:00 amSDF - SYR
2 stops7h 14mUnited Airlines
Deal found 9/15$308

Cheapflights Fare Finder

 
Customize your flight search to find flights from Syracuse to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Syracuse to Louisville that are best for you.

Fly from

Syracuse

Fly to

Louisville

Route

Depart

Return

Price

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Sat 2/21

7:30 am-1:05 pm

1 stop5h 35m

Louisville Intl

Wed 2/25

6:05 am-11:11 am

1 stop5h 06m

$249

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Tue 10/14

6:39 pm-12:01 am

1 stop5h 22m

Louisville Intl

Tue 10/21

10:15 am-5:00 pm

1 stop6h 45m

$249

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Tue 9/30

6:15 am-12:50 pm

1 stop6h 35m

Louisville Intl

Sat 10/4

5:56 pm-11:59 pm

1 stop6h 03m

$259

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Tue 9/30

10:28 am-2:51 pm

1 stop4h 23m

Louisville Intl

Sat 10/4

1:58 pm-11:42 pm

2 stops9h 44m

$264

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Sat 11/1

11:28 am-5:23 pm

1 stop5h 55m

Louisville Intl

Sun 11/2

5:25 am-11:52 am

1 stop6h 27m

$279

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Fri 11/14

5:47 pm-10:55 pm

1 stop5h 08m

Louisville Intl

Sun 11/16

6:50 am-11:40 am

1 stop4h 50m

$279

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Fri 9/26

12:15 pm-6:28 pm

1 stop6h 13m

Louisville Intl

Tue 9/30

6:00 am-11:20 am

1 stop5h 20m

$284

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Thu 11/13

7:46 pm-9:04 am

1 stop13h 18m

Louisville Intl

Sun 11/16

10:55 am-6:56 pm

1 stop8h 01m

$305

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Best time to book a flight from Syracuse to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Louisville

What is the cheapest month to book a flight from Syracuse to Louisville?

Currently, January is the cheapest month in which you can book a flight from Syracuse to Louisville (average of $299). Flying from Syracuse to Louisville in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SYR to SDF?

Find hourly flight availability from Syracuse to Louisville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

When flying from Syracuse to Louisville, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 23% versus a flight in the afternoon.

Reviews of airlines servicing Louisville

Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated September 16, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Syracuse to Louisville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,954 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Overall

8.0

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
8.0
Very good
7,954 reviews
Delta
8.0
Very good
7,954 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Overall

8.0

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
8,929 reviews
Delta
8.0
Very good
7,954 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Overall

8.0

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,954 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Overall

8.0

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Syracuse to Louisville?

    A quick flight from Syracuse to Louisville can take about 5h 35m. Delta provides one of the quickest options available for as low as $249. The distance between Syracuse and Louisville is about 608 mi.

  • What are the cheapest airlines flying from Syracuse to Louisville round-trip?

    According to our current data, Delta ($232), American Airlines ($244), and United Airlines ($318) offers the cheapest pricing from Syracuse to Louisville. Users have found that Delta is 37% cheaper than the other options available to this destination.

  • Can I find deals for flights from Syracuse to Louisville that include hotel bookings?

    Yes. In addition to deals on Syracuse to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Louisville.

  • Can I find deals for business class flights from Syracuse to Louisville?

    Yes. Cheapflights offers flight deals from Syracuse to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to Louisville?

    Currently, January is the cheapest month in which you can book a flight from Syracuse to Louisville (average of $299). Flying from Syracuse to Louisville in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Jeffersonville
Elizabethtown
Corydon
Bardstown

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Top 3 airlines flying from Syracuse to Louisville

Discover the top 3 airlines that operate flights from Syracuse to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$232Average$322FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$244Average$343FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$318Average$438FlexibilityNo cancel feeOn-time69%

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