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$149+ Cheap flights from Syracuse to Louisville (SYR - SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/3. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — SDF
Aug 28 — Sep 41
Fri 8/28
Fri 9/4
1 adult, Economy
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Cheap flight deals from Syracuse to Louisville

Cheapest flights from Syracuse to Louisville
Explore the most affordable flight options available from Syracuse to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2026.

This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/125:00 pm
SYR
-
SDF
1 stop5h 33m
American Airlines
Sat 9/196:00 am
SDF
-
SYR
1 stop4h 09m
American Airlines
Deal found 7/29$308
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/131:00 pm
SYR
-
SDF
1 stop4h 31m
American Airlines
Wed 10/216:14 pm
SDF
-
SYR
1 stop5h 43m
American Airlines
Deal found 7/26$309
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:07 am
SYR
-
SDF
1 stop4h 40m
American Airlines
Sun 11/156:00 am
SDF
-
SYR
1 stop5h 05m
American Airlines
Deal found 7/26$314
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2710:18 am
SYR
-
SDF
1 stop6h 22m
American Airlines
Thu 9/36:18 pm
SDF
-
SYR
1 stop5h 27m
American Airlines
Deal found 7/26$319
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/289:12 am
SYR
-
SDF
1 stop5h 02m
Delta
Thu 12/35:40 pm
SDF
-
SYR
1 stop5h 16m
Delta
Deal found 7/28$328
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:00 am
SYR
-
SDF
1 stop5h 05m
Delta
Sun 10/47:55 am
SDF
-
SYR
1 stop5h 00m
Delta
Deal found 7/25$329
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2212:10 pm
SYR
-
SDF
1 stop4h 46m
Delta
Sun 10/255:59 pm
SDF
-
SYR
1 stop5h 56m
Delta
Deal found 7/26$333
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/35:48 pm
SYR
-
SDF
1 stop6h 11m
United Airlines
Sun 9/67:10 am
SDF
-
SYR
2 stops7h 04m
United Airlines
Deal found 7/28$344
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/288:02 pm
SYR
-
SDF
2 stops24h 04m
Breeze Airways
Fri 9/49:28 pm
SDF
-
SYR
1 stop13h 49m
Breeze Airways
Deal found 7/28$345
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/117:58 am
SYR
-
SDF
1 stop4h 09m
American Airlines
Sat 8/156:18 pm
SDF
-
SYR
1 stop5h 27m
American Airlines
Deal found 7/26$349
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:59 pm
SYR
-
SDF
1 stop5h 00m
Delta
Sun 10/116:00 am
SDF
-
SYR
1 stop5h 09m
Delta
Deal found 7/27$366

Find flight deals from Syracuse to Louisville

Discover tips and strategies to find the most affordable flight options for your journey from Syracuse (SYR) to Louisville (SDF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$308
(American Airlines)

One-way from

$149
(Kiwi.com)

Popular in

April

Cheapest in

February

Average price

$298
Provider with most accurate pricing for Syracuse Hancock Intl-Louisville Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Syracuse Hancock Intl-Louisville Intl flights.
Search Deals
From Syracuse Hancock Intl to Louisville Intl
Search Deals
One-way flight from Syracuse Hancock Intl to Louisville Intl
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($66 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($25 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Syracuse to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2026.
Use the filters below to find and compare flights from Syracuse to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Wed 11/11

6:07 am-10:47 am

1 stop4h 40m

Louisville Intl

Sun 11/15

6:00 am-11:05 am

1 stop5h 05m

$314

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Fri 10/2

6:00 am-11:05 am

1 stop5h 05m

Louisville Intl

Sun 10/4

7:55 am-12:55 pm

1 stop5h 00m

$329
Quickest round-trip

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Sat 11/28

9:30 am-1:39 pm

1 stop4h 09m

Louisville Intl

Thu 12/3

7:30 pm-11:55 pm

1 stop4h 25m

$369

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Sun 8/23

10:25 am-2:37 pm

1 stop4h 12m

Louisville Intl

Sun 8/30

7:10 am-2:14 pm

2 stops7h 04m

$395

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Thu 10/8

6:20 am-9:57 am

1 stop3h 37m

Louisville Intl

Sun 10/11

6:00 am-11:09 am

1 stop5h 09m

$406

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Sat 11/14

10:17 am-2:47 pm

1 stop4h 30m

Louisville Intl

Wed 11/18

2:10 pm-9:29 pm

1 stop7h 19m

$409

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Wed 11/11

10:17 am-10:30 pm

2 stops12h 13m

Louisville Intl

Sun 11/15

7:00 am-2:12 pm

2 stops7h 12m

$439
Cheapest one-way

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Sun 8/23

10:56 am-9:49 am

1 stop22h 53m

$226

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Sat 10/3

3:20 pm-8:29 pm

3 stops29h 09m

$240
Quickest one-way

SyracuseLouisville

SYR - SDF

SYRSDF

Syracuse Hancock Intl

Thu 10/22

6:00 am-10:43 am

1 stop4h 43m

$274

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/27

Showing 1-10 of 16 resultsSorted by cheapest first
1
2

Compare providers for flights from Syracuse to Louisville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Syracuse to Louisville in July.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Syracuse-Louisville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Syracuse-Louisville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Syracuse-Louisville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Syracuse-Louisville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Syracuse-Louisville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Syracuse to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Louisville

What is the cheapest month to book a flight from Syracuse to Louisville?

Currently, February is the cheapest month in which you can book a flight from Syracuse to Louisville (average of $288). Flying from Syracuse to Louisville in April is currently the most expensive (average of $653). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Syracuse to Louisville?

Airfare is typical for this route at the moment.

Syracuse to Louisville flights typically cost between $308 and $536 in September.
The cheapest round-trip price found within the last 5 days was $308 on American Airlines (Sep 12-Sep 19).

Reviews of airlines servicing Louisville

Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated July 29, 2026.
Peruse reviews from past customers who have flown with Delta and American Airlines from Syracuse to Louisville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.8
Good
8,486 reviews

Entertainment

7.8

Overall

7.8

Boarding

8.1

Crew

8.5

Comfort

7.8

Food

7.2

Reviews

1 / 20
2.0
Mediocre

Barney,May 2026

JFK - ATL

Terrible flight. Late, reduced beverage service, lack of headphones, entertainment service didn't work
Delta
7.8
Good
8,486 reviews
Delta
7.8
Good
8,486 reviews

Entertainment

7.8

Overall

7.8

Boarding

8.1

Crew

8.5

Comfort

7.8

Food

7.2

Reviews

1 / 20
2.0
Mediocre

Barney,May 2026

JFK - ATL

Terrible flight. Late, reduced beverage service, lack of headphones, entertainment service didn't work
American Airlines
7.1
Good
11,839 reviews
Delta
7.8
Good
8,486 reviews

Entertainment

7.8

Overall

7.8

Boarding

8.1

Crew

8.5

Comfort

7.8

Food

7.2

Reviews

1 / 20
2.0
Mediocre

Barney,May 2026

JFK - ATL

Terrible flight. Late, reduced beverage service, lack of headphones, entertainment service didn't work

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Syracuse to Louisville?

    A quick flight from Syracuse to Louisville can take about 4h 12m. American Airlines provides one of the quickest options available for as low as $395. The distance between Syracuse and Louisville is about 608 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Syracuse to Louisville round-trip?

    According to our current data, Delta ($193), and American Airlines ($248) offers the cheapest pricing from Syracuse to Louisville. Users have found that Delta is 49% cheaper than the other options available to this destination.

  • Can I find deals for flights from Syracuse to Louisville that include hotel bookings?

    Yes. In addition to deals on Syracuse to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Louisville.

  • Can I find deals for business class flights from Syracuse to Louisville?

    Yes. Cheapflights offers flight deals from Syracuse to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to Louisville?

    Currently, February is the cheapest month in which you can book a flight from Syracuse to Louisville (average of $288). Flying from Syracuse to Louisville in April is currently the most expensive (average of $653). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Corydon
Shepherdsville
Elizabethtown
Jeffersonville
Bardstown

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Syracuse to Louisville

Discover the top 2 airlines that operate flights from Syracuse to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$193Average$386FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$376FlexibilityNo cancel feeOn-time71%

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