$153+ Cheap flights from Syracuse (SYR) to Santo Domingo (SDQ)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/12. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — SDQ
Nov 24 — Dec 11
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Syracuse to Santo Domingo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Syracuse to Santo Domingo
Cheapest
Best
Last-minute
One-way
Cheapest flights from Syracuse to Santo DomingoExplore the most affordable flight options available from Syracuse to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
Explore the most affordable flight options available from Syracuse to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
This JetBlue deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:40 am -
1 stop7h 40m
Sat 12/122:43 pm -
1 stop10h 16m
Deal found 10/21![JetBlue logo]()
$495
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/54:55 pm -
2 stops16h 10m
Sat 12/123:55 pm -
1 stop9h 00m
Deal found 10/21![American Airlines logo]()
$505
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/94:58 pm -
2 stops16h 07m
Wed 12/164:59 pm -
2 stops19h 01m
Deal found 10/24![American Airlines logo]()
$512
This JetBlue deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/97:40 am -
1 stop7h 40m
Wed 12/162:43 pm -
1 stop10h 16m
Deal found 10/24![JetBlue logo]()
$585
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/105:33 pm -
2 stops15h 32m
Wed 12/306:14 pm -
2 stops17h 46m
Deal found 10/22![American Airlines logo]()
$719
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:00 am -
1 stop6h 50m
Fri 11/276:00 am -
2 stops17h 43m
Deal found 10/25![American Airlines logo]()
$726
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/134:58 pm -
2 stops16h 07m
Sun 1/176:00 am -
2 stops18h 19m
Deal found 10/21![American Airlines logo]()
$727
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/217:04 pm -
1 stop17h 46m
Fri 11/276:00 am -
2 stops17h 43m
Deal found 10/25![American Airlines logo]()
$730
This JetBlue deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/109:00 am -
1 stop8h 54m
Wed 12/302:51 pm -
1 stop9h 58m
Deal found 10/22![JetBlue logo]()
$744
This JetBlue deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:40 am -
1 stop7h 40m
Sat 12/53:35 am -
1 stop13h 09m
Deal found 10/21![JetBlue logo]()
$758
Best flights from Syracuse to Santo DomingoDiscover carefully curated flight deals from Syracuse to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
Discover carefully curated flight deals from Syracuse to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
This JetBlue deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/97:40 am -
1 stop7h 40m
Wed 12/162:43 pm -
1 stop10h 16m
Deal found 10/24![JetBlue logo]()
$585
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/257:25 pm -
2 stops18h 41m
Fri 1/292:53 pm -
2 stops24h 26m
Deal found 10/22![United Airlines logo]()
$589
This JetBlue deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/257:35 am -
1 stop7h 44m
Fri 1/292:46 pm -
1 stop10h 13m
Deal found 10/20![JetBlue logo]()
$674
This JetBlue deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/109:00 am -
1 stop8h 54m
Wed 12/302:51 pm -
1 stop9h 58m
Deal found 10/22![JetBlue logo]()
$744
This JetBlue deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/227:30 am -
1 stop7h 49m
Sat 11/284:15 pm -
1 stop8h 44m
Deal found 10/21![JetBlue logo]()
$793
This Justfly.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/137:40 am -
1 stop7h 40m
Sun 1/175:34 pm -
1 stop7h 25m
Deal found 10/25![JetBlue logo]()
$1,071
Last-minute flights from Syracuse to Santo DomingoDiscover last-minute flight deals from Syracuse to Santo Domingo. Data last updated October 25, 2026 and is based on user searches.
Discover last-minute flight deals from Syracuse to Santo Domingo. Data last updated October 25, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:00 am -
1 stop6h 50m
Fri 11/276:00 am -
2 stops17h 43m
Deal found 10/25![American Airlines logo]()
$726
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:40 am -
2 stops17h 06m
Fri 11/272:53 pm -
2 stops9h 50m
Deal found 10/25![United Airlines logo]()
$1,093
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/217:04 pm -
1 stop17h 46m
Fri 11/276:00 am -
2 stops17h 43m
Deal found 10/25![American Airlines logo]()
$730
This Cheapflightsfares deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/217:30 am -
1 stop7h 49m
Fri 11/278:10 am -
1 stop12h 50m
Deal found 10/25![JetBlue logo]()
$849
This JetBlue deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:00 am -
1 stop8h 04m
Sat 11/2812:10 pm -
1 stop12h 49m
Deal found 10/24![JetBlue logo]()
$873
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:21 pm -
2 stops15h 44m
Sat 11/286:00 am -
2 stops17h 43m
Deal found 10/24![American Airlines logo]()
$915
This JetBlue deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/227:30 am -
1 stop7h 49m
Sat 11/284:15 pm -
1 stop8h 44m
Deal found 10/21![JetBlue logo]()
$793
One-way flights from Syracuse to Santo DomingoSearch for one-way flight options from Syracuse to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
Search for one-way flight options from Syracuse to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/124:25 pm -
2 stops16h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![American Airlines logo]()
$153
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/135:11 pm -
2 stops15h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![American Airlines logo]()
$158
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/117:25 pm -
2 stops17h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![United Airlines logo]()
$159
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/1111:19 am -
1 stop25h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![American Airlines logo]()
$174
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/124:35 pm -
1 stop6h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Delta logo]()
$183
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/144:40 pm -
1 stop8h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Delta logo]()
$233
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:35 pm -
2 stops17h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![United Airlines logo]()
$239
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:00 am -
1 stop6h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![American Airlines logo]()
$254
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/127:25 pm -
3 stops18h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![United Airlines logo]()
$270
Find flight deals from Syracuse to Santo Domingo
Discover tips and strategies to find the most affordable flight options for your journey from Syracuse (SYR) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 25, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $495 (JetBlue) |
One-way from | $153 (American Airlines) |
Popular in | February |
Cheapest in | June |
Average price | $456 |
Cheapflights Fare Finder
Customize your flight search to find flights from Syracuse to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
Use the filters below to find and compare flights from Syracuse to Santo Domingo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
SyracuseSanto Domingo
SYR Syracuse Hancock Intl - SDQ Santo Domingo Las Americas
SYRSDQ
Syracuse Hancock Intl
Mon 1/11
7:25 pm-1:41 pm
2 stops17h 16m
Santo Domingo Las Americas
Wed 12/31
12:00 am-11:30 pm
Nonstop0h 00m
$159
SyracuseSanto Domingo
SYR Syracuse Hancock Intl - SDQ Santo Domingo Las Americas
SYRSDQ
Syracuse Hancock Intl
Tue 1/12
4:35 pm-12:30 am
1 stop6h 55m
Santo Domingo Las Americas
Wed 12/31
12:00 am-11:30 pm
Nonstop0h 00m
$183
SyracuseSanto Domingo
SYR Syracuse Hancock Intl - SDQ Santo Domingo Las Americas
SYRSDQ
Syracuse Hancock Intl
Fri 11/13
5:29 am-7:30 pm
1 stop13h 01m
Santo Domingo Las Americas
Wed 12/31
12:00 am-11:30 pm
Nonstop0h 00m
$233
SyracuseSanto Domingo
SYR Syracuse Hancock Intl - SDQ Santo Domingo Las Americas
SYRSDQ
Syracuse Hancock Intl
Sat 11/14
4:40 pm-2:14 am
1 stop8h 34m
Santo Domingo Las Americas
Wed 12/31
12:00 am-11:30 pm
Nonstop0h 00m
$233
SyracuseSanto Domingo
SYR Syracuse Hancock Intl - SDQ Santo Domingo Las Americas
SYRSDQ
Syracuse Hancock Intl
Fri 11/13
7:35 pm-1:41 pm
2 stops17h 06m
Santo Domingo Las Americas
Wed 12/31
12:00 am-11:30 pm
Nonstop0h 00m
$239
Quickest round-trip
SyracuseSanto Domingo
SYR Syracuse Hancock Intl - SDQ Santo Domingo Las Americas
SYRSDQ
Syracuse Hancock Intl
Tue 12/1
6:00 am-1:50 pm
1 stop6h 50m
Santo Domingo Las Americas
Wed 12/31
12:00 am-11:30 pm
Nonstop0h 00m
$254
SyracuseSanto Domingo
SYR Syracuse Hancock Intl - SDQ Santo Domingo Las Americas
SYRSDQ
Syracuse Hancock Intl
Tue 1/12
7:25 pm-3:06 pm
3 stops18h 41m
Santo Domingo Las Americas
Wed 12/31
12:00 am-11:30 pm
Nonstop0h 00m
$270
SyracuseSanto Domingo
SYR Syracuse Hancock Intl - SDQ Santo Domingo Las Americas
SYRSDQ
Syracuse Hancock Intl
Fri 12/11
7:50 pm-1:41 pm
2 stops16h 51m
Santo Domingo Las Americas
Wed 12/31
12:00 am-11:30 pm
Nonstop0h 00m
$435
SyracuseSanto Domingo
SYR Syracuse Hancock Intl - SDQ Santo Domingo Las Americas
SYRSDQ
Syracuse Hancock Intl
Tue 12/15
9:00 am-6:54 pm
1 stop8h 54m
Santo Domingo Las Americas
Wed 12/31
12:00 am-11:30 pm
Nonstop0h 00m
$462
SyracuseSanto Domingo
SYR Syracuse Hancock Intl - SDQ Santo Domingo Las Americas
SYRSDQ
Syracuse Hancock Intl
Tue 12/15
7:00 am-7:53 pm
2 stops11h 53m
Santo Domingo Las Americas
Wed 12/31
12:00 am-11:30 pm
Nonstop0h 00m
$474
Showing 1-10 of 16 resultsSorted by cheapest first
Compare providers for flights from Syracuse to Santo Domingo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Syracuse to Santo Domingo in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Syracuse-Santo Domingo flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Syracuse-Santo Domingo flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Syracuse-Santo Domingo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Syracuse-Santo Domingo flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Syracuse-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Syracuse to Santo Domingo
Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Syracuse with our price prediction graph.
SYR-SDQ
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Syracuse to Santo Domingo
What is the cheapest month to book a flight from Syracuse to Santo Domingo?
Currently, June is the cheapest month in which you can book a flight from Syracuse to Santo Domingo (average of $433). Flying from Syracuse to Santo Domingo in February is currently the most expensive (average of $837). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Syracuse to Santo Domingo?
Airfare is below average for this route at the moment.
Syracuse to Santo Domingo flights typically cost between $507 and $631 in December.The cheapest round-trip price found within the last 5 days was $495 on JetBlue (Dec 5-Dec 12).
Reviews of airlines servicing Santo Domingo
Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated October 25, 2026.
Read through reviews of airlines operating flights from Syracuse to Santo Domingo, such as Delta,JetBlue, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Food
7.2
Overall
7.8
Entertainment
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Comfort
7.8
Food
7.2
Overall
7.8
Entertainment
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Comfort
7.8
Food
7.2
Overall
7.8
Entertainment
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Comfort
7.8
Food
7.2
Overall
7.8
Entertainment
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Related info for your journey
Find useful and relevant information for your journey from Syracuse to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Santo Domingo?
Book flights to Santo Domingo if you plan to visit one of these locationsJuan Dolio
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Syracuse
Popular flights
Santo Domingo flight routes
Alternative routes for Syracuse to Santo Domingo
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Santo Domingo by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Syracuse to Santo Domingo by cabin class
Find flights from Syracuse to Santo Domingo, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Syracuse and Santo Domingo flights
Browse other Syracuse and Santo Domingo flight options. Last updated on October 25, 2026.
Other flights from Syracuse
Browse through other flights departing from Syracuse. Flights are based on user searches made on Cheapflights and were last updated on October 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santo Domingo
Explore flights to Santo Domingo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 25, 2026.
Top 3 airlines flying from Syracuse to Santo Domingo
Discover the top 3 airlines that operate flights from Syracuse to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$376 | Average$467 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$443 | Average$687 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$532 | Average$827 | FlexibilityNo cancel fee | On-time71% |