HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Louisville

$119+ Cheap flights from Panama City, FL to Louisville (ECP - SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/22. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — SDF
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Panama City to Louisville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Panama City to Louisville

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Louisville (SDF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 31, 2025.

Round-trip from

$237
(United Airlines)

One-way from

$119
(Delta)

Popular in

July

Cheapest in

August

Average price

$683
From Panama City NW Florida Beaches to Louisville Intl
Search Deals
One-way flight from Panama City NW Florida Beaches to Louisville Intl
Search Deals
Highest demand for flights based on searches. 0% potential increase in price ($1 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($26 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2025
Search Deals

Find flight deals from Panama City to Louisville

Cheapest flights from Panama City to Louisville
Explore the most affordable flight options available from Panama City to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/211:44 pmECP - SDF
1 stop7h 40mUnited Airlines
Wed 8/277:00 amSDF - ECP
1 stop7h 03mUnited Airlines
Deal found 7/30$237
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/213:22 pmECP - SDF
1 stop5h 29mAmerican Airlines
Wed 8/273:09 pmSDF - ECP
2 stops8h 00mAmerican Airlines
Deal found 7/30$242
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/269:24 amECP - SDF
1 stop4h 02mDelta
Thu 8/286:00 amSDF - ECP
1 stop3h 19mDelta
Deal found 7/29$292
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/156:35 amECP - SDF
1 stop7h 15mSouthwest
Mon 8/186:25 amSDF - ECP
1 stop4h 30mSouthwest
Deal found 7/29$407

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Panama City to Louisville that are best for you.

Fly from

Panama City

Fly to

Louisville

Route

Depart

Return

Price

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

Thu 8/21

1:44 pm-10:24 pm

1 stop7h 40m

Louisville Intl

Wed 8/27

7:00 am-1:03 pm

1 stop7h 03m

$237

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

Thu 8/21

3:22 pm-9:51 pm

1 stop5h 29m

Louisville Intl

Wed 8/27

3:09 pm-10:09 pm

2 stops8h 00m

$242

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

Tue 8/26

9:24 am-2:26 pm

1 stop4h 02m

Louisville Intl

Thu 8/28

6:00 am-8:19 am

1 stop3h 19m

$292

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

Fri 8/15

6:35 am-2:50 pm

1 stop7h 15m

Louisville Intl

Mon 8/18

6:25 am-9:55 am

1 stop4h 30m

$407

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

Fri 8/22

9:24 am-2:26 pm

1 stop4h 02m

$119

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

Sat 8/23

5:30 am-2:19 pm

2 stops7h 49m

$124

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

Fri 8/22

1:35 pm-10:50 pm

2 stops8h 15m

$199

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Best time to book a flight from Panama City to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Louisville

What is the cheapest month to book a flight from Panama City, Florida to Louisville?

Currently, January is the cheapest month in which you can book a flight from Panama City, Florida to Louisville (average of $299). Flying from Panama City, Florida to Louisville in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to SDF?

Find hourly flight availability from Panama City to Louisville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

A simple way to save on the total cost of your ticket is to fly from Panama City, Florida to Louisville at noon. If you’re flexible enough to do this you can expect to save up to 31% on your trip compared to booking a flight in the afternoon.

Reviews of airlines servicing Louisville

Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated July 31, 2025.
Read through reviews of airlines operating flights from Panama City to Louisville, such as Southwest, Delta, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,246 reviews

Food

7.0

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Southwest
8.0
Very good
4,246 reviews
Southwest
8.0
Very good
4,246 reviews

Food

7.0

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Delta
8.0
Very good
7,981 reviews
Southwest
8.0
Very good
4,246 reviews

Food

7.0

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
United Airlines
7.4
Good
8,900 reviews
Southwest
8.0
Very good
4,246 reviews

Food

7.0

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,246 reviews

Food

7.0

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Panama City, Florida to Louisville round-trip?

    United Airlines, at $237, was found to be the cheapest airline from Panama City, Florida to Louisville.Alternate airlines to your destination round-trip include American Airlines and Delta. These flights start at 42% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Panama City, Florida to Louisville one-way?

    The cheapest airlines for a one-way flight from Panama City, Florida to Louisville are Delta ($119), American Airlines ($124), and Southwest ($199).

  • Can I find deals for flights from Panama City to Louisville that include hotel bookings?

    Yes. In addition to deals on Panama City to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Louisville.

  • Can I find deals for business class flights from Panama City to Louisville?

    Yes. Cheapflights offers flight deals from Panama City to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Louisville?

    Currently, January is the cheapest month in which you can book a flight from Panama City, Florida to Louisville (average of $299). Flying from Panama City, Florida to Louisville in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Jeffersonville
Elizabethtown
Corydon
Bardstown

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama City to Louisville

See prices for flight routes from nearby airports that may be better suited for you.
Fort Lauderdale to Nashville flights
Orlando to Nashville flights
Tampa to Nashville flights
Miami to Nashville flights
Pensacola to Nashville flights
West Palm Beach to Nashville flights
Panama City to Nashville flights
Tampa to Cincinnati flights
Fort Lauderdale to Knoxville flights
Fort Myers to Nashville flights
Orlando to Cincinnati flights
Miami to Louisville flights
Miami to Knoxville flights
Jacksonville to Nashville flights
Orlando to Louisville flights
Miami to Cincinnati flights
Orlando Sanford Intl to Knoxville flights
Fort Myers to Cincinnati flights
Tampa to Louisville flights
Fort Lauderdale to Cincinnati flights
Jacksonville to Louisville flights
Orlando to Knoxville flights
Fort Lauderdale to Louisville flights
West Palm Beach to Knoxville flights
Sarasota to Nashville flights
Tampa to Knoxville flights
Orlando to Lexington flights
St Petersburg to Cincinnati flights
Orlando Sanford Intl to Cincinnati flights
Tampa to Lexington flights
West Palm Beach to Cincinnati flights
Sarasota to Lexington flights
St Petersburg to Knoxville flights
Jacksonville to Cincinnati flights
Fort Myers to Knoxville flights
Fort Lauderdale to Lexington flights
West Palm Beach to Louisville flights
Sarasota to Knoxville flights
Tallahassee to Nashville flights
West Palm Beach to Lexington flights
Pensacola to Knoxville flights
Jacksonville to Lexington flights
Sarasota to Cincinnati flights
Miami to Lexington flights
Pensacola to Cincinnati flights
Fort Lauderdale to Blountville flights
Gainesville to Nashville flights
Tampa to Blountville flights
Daytona Beach to Louisville flights
Key West to Nashville flights

Top 2 airlines flying from Panama City to Louisville

Discover the top 2 airlines that operate flights from Panama City to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$227Average$517FlexibilityNo cancel feeOn-time71%
DeltaCheapest$236Average$348FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.