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$119+ Cheap flights from Panama City, FL to Louisville (ECP - SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/24. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — SDF
out 15 — out 221
qua 10/15
qua 10/22
1 adult, Economy
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Cheap flight deals from Panama City to Louisville

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Louisville (SDF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated setembro 15, 2025.

Round-trip from

$217
(Delta)

One-way from

$119
(United Airlines)

Popular in

January

Cheapest in

August

Average price

$558
From Panama City NW Florida Beaches to Louisville Intl
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One-way flight from Panama City NW Florida Beaches to Louisville Intl
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Highest demand for flights based on searches. 27% potential increase in price ($153 potential increase over avg. RT price).
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Cheapest flight prices on average. 9% potential price decrease ($38 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Panama City to Louisville

Cheapest flights from Panama City to Louisville
Explore the most affordable flight options available from Panama City to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on setembro 15, 2025.

This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 12/27:02 amECP - SDF
1 stop6h 11mDelta
qua 12/103:18 pmSDF - ECP
1 stop4h 43mDelta
Deal found 9/14$217
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 12/27:02 amECP - SDF
1 stop6h 11mDelta
seg 12/83:18 pmSDF - ECP
1 stop6h 14mDelta
Deal found 9/14$227
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 11/275:09 pmECP - SDF
1 stop4h 39mDelta
seg 12/87:59 pmSDF - ECP
1 stop3h 59mDelta
Deal found 9/14$237
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 12/25:00 pmECP - SDF
1 stop6h 05mDelta
sex 12/127:59 pmSDF - ECP
1 stop3h 59mDelta
Deal found 9/14$244
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 11/275:09 pmECP - SDF
1 stop4h 39mDelta
sex 12/127:59 pmSDF - ECP
1 stop3h 59mDelta
Deal found 9/14$254
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 11/267:02 amECP - SDF
1 stop6h 02mDelta
qua 12/1012:57 pmSDF - ECP
1 stop3h 34mDelta
Deal found 9/14$292
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 11/266:40 pmECP - SDF
1 stop4h 26mDelta
qui 12/117:59 pmSDF - ECP
1 stop3h 59mDelta
Deal found 9/14$302
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 11/277:15 amECP - SDF
1 stop5h 08mAmerican Airlines
seg 12/81:02 pmSDF - ECP
2 stops11h 08mAmerican Airlines
Deal found 9/14$312
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sex 11/284:26 pmECP - SDF
1 stop5h 22mDelta
qua 12/106:00 amSDF - ECP
1 stop4h 13mDelta
Deal found 9/14$317
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 11/265:00 pmECP - SDF
1 stop6h 06mDelta
sex 12/127:59 pmSDF - ECP
1 stop3h 59mDelta
Deal found 9/14$319
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sex 11/284:26 pmECP - SDF
1 stop5h 22mDelta
sáb 12/66:11 pmSDF - ECP
1 stop5h 27mDelta
Deal found 9/14$327
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 11/276:47 amECP - SDF
1 stop5h 15mAmerican Airlines
sex 12/126:30 amSDF - ECP
2 stops11h 48mAmerican Airlines
Deal found 9/14$329

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated setembro 15, 2025.
Use the filters below to find and compare flights from Panama City to Louisville that are best for you.

Fly from

Panama City

Fly to

Louisville

Route

Depart

Return

Price

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

ter 12/2

5:00 pm-9:30 pm

1 stop3h 30m

Louisville Intl

qui 12/11

3:18 pm-8:32 pm

1 stop6h 14m

$227

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

ter 12/2

5:00 pm-9:30 pm

1 stop3h 30m

Louisville Intl

sáb 12/6

6:11 pm-10:38 pm

1 stop5h 27m

$227

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

ter 12/2

7:02 am-2:13 pm

1 stop6h 11m

Louisville Intl

seg 12/8

3:18 pm-8:32 pm

1 stop6h 14m

$227

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

qui 11/27

5:09 pm-10:48 pm

1 stop4h 39m

Louisville Intl

qua 12/10

6:00 am-9:13 am

1 stop4h 13m

$227

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

qui 11/27

5:09 pm-10:48 pm

1 stop4h 39m

Louisville Intl

qui 12/11

7:59 pm-10:58 pm

1 stop3h 59m

$237

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

qui 11/27

5:09 pm-10:48 pm

1 stop4h 39m

Louisville Intl

sáb 12/6

6:00 am-9:13 am

1 stop4h 13m

$237

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

ter 12/2

5:00 pm-12:05 am

1 stop6h 05m

Louisville Intl

sex 12/12

7:59 pm-10:58 pm

1 stop3h 59m

$244

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

ter 12/2

5:00 pm-9:30 pm

1 stop3h 30m

Louisville Intl

dom 12/7

6:00 am-9:13 am

1 stop4h 13m

$292

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

seg 12/1

7:02 am-2:04 pm

1 stop6h 02m

Louisville Intl

ter 12/9

12:57 pm-3:53 pm

1 stop3h 56m

$292

Panama CityLouisville

ECP - SDF

ECPSDF

Panama City NW Florida Beaches

seg 12/1

6:40 pm-12:06 am

1 stop4h 26m

Louisville Intl

qua 12/10

6:00 am-9:13 am

1 stop4h 13m

$292

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 22 results
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2
3

Best time to book a flight from Panama City to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Louisville

What is the cheapest month to book a flight from Panama City, Florida to Louisville?

Currently, January is the cheapest month in which you can book a flight from Panama City, Florida to Louisville (average of $299). Flying from Panama City, Florida to Louisville in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to SDF?

Find hourly flight availability from Panama City to Louisville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated setembro 15, 2025.

A simple way to save on the total cost of your ticket is to fly from Panama City, Florida to Louisville at noon. If you’re flexible enough to do this you can expect to save up to 31% on your trip compared to booking a flight in the afternoon.

Reviews of airlines servicing Louisville

Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated setembro 15, 2025.
Read through reviews of airlines operating flights from Panama City to Louisville, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,954 reviews

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
8.0
Very good
7,954 reviews
Delta
8.0
Very good
7,954 reviews

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,954 reviews

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City, Florida to Louisville?

    Delta can get you from Panama City, Florida to Louisville in just under 3h 30m. Your travel time can differ by up to . The distance from Panama City, Florida to Louisville is about 540 mi.

  • What are the cheapest airlines flying from Panama City, Florida to Louisville round-trip?

    American Airlines, at $236, was found to be the cheapest airline from Panama City, Florida to Louisville. An alternate airline flying to your destination would be Delta. These flights start at 42% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Panama City, Florida to Louisville one-way?

    The cheapest airlines for a one-way flight from Panama City, Florida to Louisville are United Airlines ($119), Delta ($136), and American Airlines ($170).

  • Can I find deals for flights from Panama City to Louisville that include hotel bookings?

    Yes. In addition to deals on Panama City to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Louisville.

  • Can I find deals for business class flights from Panama City to Louisville?

    Yes. Cheapflights offers flight deals from Panama City to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Louisville?

    Currently, January is the cheapest month in which you can book a flight from Panama City, Florida to Louisville (average of $299). Flying from Panama City, Florida to Louisville in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Jeffersonville
Elizabethtown
Corydon
Bardstown

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Alternative routes for Panama City to Louisville

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Top 2 airlines flying from Panama City to Louisville

Discover the top 2 airlines that operate flights from Panama City to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated setembro 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$236Average$371FlexibilityNo cancel feeOn-time71%
DeltaCheapest$236Average$374FlexibilityNo cancel feeOn-timeN/A

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