How long is the flight from Florida Keys to Louisville?

American Airlines, Delta, and United Airlines can get you from Florida Keys to Louisville in just under 2h 47m. Your travel time can differ by up to 4h 34m. The distance from Florida Keys to Louisville is about 912 mi. This flight may include one or multiple stops.

What are the cheapest airlines to fly from Florida Keys to Louisville one-way?

To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $43. Allegiant Air flights start at $48 while deals on Southwest start at $89 one-way.

In terms of precipitation, rainfall in Louisville ranges from 3.1 - 5.3 inches per month. May is typically the wettest month, when rainfall can reach 5.3 in. September is typically the driest time to visit Louisville when rainfall is around 3.1 in.

If weather is an important factor for your trip to Louisville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 35.6 F).

What are the most popular airlines that fly from Florida Keys to Louisville?

American Airlines, Southwest and Delta are the most popular airlines when flying from Florida Keys to Louisville.

What is the cheapest time of day to fly from EOA to SDF?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Florida Keys to Louisville as you normally would.

What airport do you fly into for flights to Louisville from Florida Keys?

Louisville Intl (SDF), located 5.3 mi from the city center, is the airport you fly into when you book flights from Florida Keys to Louisville.

Can I find deals for flights from Florida Keys to Louisville that include hotel bookings?

Yes. In addition to deals on Florida Keys to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Florida Keys to Louisville?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florida Keys to Louisville.

Can I find deals for business class flights from Florida Keys to Louisville?

Yes. Cheapflights offers flight deals from Florida Keys to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$86+ Flights from Florida Keys to Louisville

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Cheap flight deals from Florida Keys to Louisville

Cheapest flights from Florida Keys to Louisville
Explore the most affordable flight options available from Florida Keys to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 30, 2025.

Wed 12/319:20 pmMIA - SDF

Nonstop2h 39mAmerican Airlines

Tue 1/66:00 amSDF - MIA

Nonstop2h 55mAmerican Airlines

Deal found 12/28

$273

Wed 12/315:01 pmMIA - SDF

1 stop6h 55mDelta

Tue 1/66:00 amSDF - MIA

1 stop4h 39mDelta

Deal found 12/28

$293

Wed 12/319:20 pmMIA - SDF

Nonstop2h 39mAmerican Airlines

Fri 1/25:00 amSDF - MIA

Nonstop2h 39mAmerican Airlines

Deal found 12/30

$302

Wed 12/312:10 pmMIA - SDF

1 stop8h 20mUnited Airlines

Fri 1/25:40 amSDF - MIA

1 stop6h 30mUnited Airlines

Deal found 12/30

$322

Wed 12/317:10 amMIA - SDF

2 stops9h 25mSouthwest

Fri 1/27:00 pmSDF - MIA

1 stop4h 00mSouthwest

Deal found 12/27

$359

Sun 12/289:20 pmMIA - SDF

Nonstop2h 39mAmerican Airlines

Sun 1/45:00 amSDF - MIA

Nonstop2h 39mAmerican Airlines

Deal found 12/27

$363

Wed 12/318:45 amMIA - SDF

1 stop5h 59mUnited Airlines

Tue 1/68:29 amSDF - MIA

2 stops13h 51mUnited Airlines

Deal found 12/28

$368

Sun 12/2811:56 amMIA - SDF

1 stop8h 03mUnited Airlines

Mon 1/510:50 amSDF - MIA

1 stop7h 45mUnited Airlines

Deal found 12/27

$383

Best flights from Florida Keys to Louisville
Discover carefully curated flight deals from Florida Keys to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 30, 2025.

Fri 2/610:29 amMIA - SDF

1 stop6h 32mDelta

Mon 2/910:41 amSDF - MIA

1 stop7h 04mDelta

Deal found 12/28

$199

Tue 1/279:12 pmMIA - SDF

Nonstop2h 47mAmerican Airlines

Mon 2/212:00 pmSDF - MIA

Nonstop2h 36mAmerican Airlines

Deal found 12/29

$239

Fri 2/66:30 amMIA - SDF

1 stop6h 15mSouthwest

Mon 2/96:25 amSDF - MIA

2 stops10h 45mSouthwest

Deal found 12/28

$254

Sun 1/256:02 amMIA - SDF

2 stops30h 58mSpirit Airlines

Sun 2/13:36 pmSDF - MIA

2 stops20h 20mSpirit Airlines

Deal found 12/28

$274

Thu 1/224:15 pmEYW - SDF

1 stop6h 15mUnited Airlines

Sun 1/259:50 amSDF - EYW

1 stop6h 32mUnited Airlines

Deal found 12/28

$349

Wed 2/47:15 amMIA - SDF

1 stop4h 22mDelta

Sun 2/83:32 pmSDF - MIA

1 stop5h 12mDelta

Deal found 12/27

$199

Fri 1/307:15 amMIA - SDF

1 stop7h 21mDelta

Sun 2/17:51 pmSDF - MIA

1 stop5h 00mDelta

Deal found 12/28

$199

Wed 2/44:30 pmMIA - SDF

1 stop6h 15mSouthwest

Thu 2/56:25 amSDF - MIA

2 stops10h 45mSouthwest

Deal found 12/27

$254

Wed 2/115:30 pmMIA - SDF

1 stop6h 20mDelta

Wed 2/1810:46 amSDF - MIA

1 stop6h 35mDelta

Deal found 12/29

$219

Tue 1/276:55 amMIA - SDF

1 stop4h 15mSouthwest

Mon 2/212:50 pmSDF - MIA

1 stop5h 45mSouthwest

Deal found 12/29

$259

Tue 1/207:15 amMIA - SDF

1 stop6h 20mSouthwest

Tue 1/205:45 pmSDF - MIA

1 stop4h 15mSouthwest

Deal found 12/29

$261

Wed 5/204:20 pmEYW - SDF

1 stop5h 48mAmerican Airlines

Sat 5/237:35 amSDF - EYW

1 stop6h 07mAmerican Airlines

Deal found 12/28

$367

Last-minute flights from Florida Keys to Louisville
Discover last-minute flight deals from Florida Keys to Louisville. Data last updated December 30, 2025 and is based on user searches.

Wed 12/319:20 pmMIA - SDF

Nonstop2h 39mAmerican Airlines

Tue 1/66:00 amSDF - MIA

Nonstop2h 55mAmerican Airlines

Deal found 12/28

$273

Thu 1/86:05 pmEYW - SDF

1 stop25h 38mUnited Airlines

Sun 1/118:29 amSDF - EYW

1 stop6h 48mUnited Airlines

Deal found 12/27

$583

Tue 1/207:15 amMIA - SDF

1 stop6h 20mSouthwest

Tue 1/205:45 pmSDF - MIA

1 stop4h 15mSouthwest

Deal found 12/29

$261

Thu 1/224:15 pmEYW - SDF

1 stop6h 15mUnited Airlines

Sun 1/259:50 amSDF - EYW

1 stop6h 32mUnited Airlines

Deal found 12/29

$349

Sun 1/259:12 pmMIA - SDF

Nonstop2h 47mAmerican Airlines

Sun 2/16:00 amSDF - MIA

Nonstop2h 55mAmerican Airlines

Deal found 12/28

$271

Sun 1/256:02 amMIA - SDF

2 stops30h 58mSpirit Airlines

Sun 2/13:36 pmSDF - MIA

2 stops20h 20mSpirit Airlines

Deal found 12/28

$274

Tue 1/276:04 amMIA - SDF

1 stop7h 39mAmerican Airlines

Mon 2/26:00 amSDF - MIA

Nonstop2h 55mAmerican Airlines

Deal found 12/29

$249

Tue 1/276:55 amMIA - SDF

1 stop4h 15mSouthwest

Mon 2/212:50 pmSDF - MIA

1 stop5h 45mSouthwest

Deal found 12/29

$259

Fri 1/308:25 amMIA - SDF

Nonstop2h 50mAmerican Airlines

Sun 2/16:00 amSDF - MIA

Nonstop2h 55mAmerican Airlines

Deal found 12/30

$179

Fri 1/307:15 amMIA - SDF

1 stop7h 21mDelta

Sun 2/17:51 pmSDF - MIA

1 stop5h 00mDelta

Deal found 12/28

$199

One-way flights from Florida Keys to Louisville
Search for one-way flight options from Florida Keys to Louisville. Find affordable one-way fares based on user searches. Data last updated December 30, 2025.

Sat 2/287:00 amMIA - SDF

1 stop5h 40mSouthwest

Deal found 12/30

$86

Tue 1/275:20 pmMIA - SDF

1 stop4h 30mSouthwest

Deal found 12/28

$100

Thu 3/266:00 amMIA - SDF

1 stop7h 26mMultiple Airlines

Deal found 12/30

$102

Thu 2/267:05 amMIA - SDF

2 stops25h 35mMultiple Airlines

Deal found 12/30

$106

Wed 2/116:59 pmMIA - SDF

2 stops25h 38mMultiple Airlines

Deal found 12/30

$108

Mon 1/267:00 amMIA - SDF

2 stops31h 41mMultiple Airlines

Deal found 12/30

$114

Tue 1/274:01 pmMIA - SDF

2 stops20h 59mSpirit Airlines

Deal found 12/30

$117

Sun 3/15:05 amMIA - SDF

2 stops27h 35mMultiple Airlines

Deal found 12/27

$118

Sat 1/179:12 pmMIA - SDF

Nonstop2h 47mAmerican Airlines

Deal found 12/30

$119

Tue 1/277:00 amMIA - SDF

2 stops30h 00mMultiple Airlines

Deal found 12/30

$120

Mon 1/267:00 amMIA - SDF

2 stops31h 41mSpirit Airlines

Deal found 12/28

$121

Find flight deals from Florida Keys to Louisville

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$179 (American Airlines)
One-way from	$100 (Southwest)

Provider with most accurate pricing for Key West-Louisville Intl flight deals.

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From Florida Keys to Louisville Intl

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One-way flight from Florida Keys to Louisville Intl

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Cheapflights Fare Finder

Use the filters below to find and compare flights from Florida Keys to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MiamiLouisville

MIA - SDF

MIASDF

Miami

Fri 2/6

10:29 am-5:01 pm

1 stop6h 32m

Louisville Intl

Mon 2/9

10:41 am-5:45 pm

1 stop7h 04m

$199

MiamiLouisville

MIA - SDF

MIASDF

Miami

Wed 2/4

7:15 am-11:37 am

1 stop4h 22m

Louisville Intl

Sun 2/8

3:32 pm-8:44 pm

1 stop5h 12m

$199

MiamiLouisville

MIA - SDF

MIASDF

Miami

Fri 1/30

7:15 am-2:36 pm

1 stop7h 21m

Louisville Intl

Sun 2/1

7:51 pm-12:51 am

1 stop5h 00m

$199

MiamiLouisville

MIA - SDF

MIASDF

Miami

Wed 2/11

5:30 pm-11:50 pm

1 stop6h 20m

Louisville Intl

Wed 2/18

10:46 am-5:21 pm

1 stop6h 35m

$219

MiamiLouisville

MIA - SDF

MIASDF

Miami

Tue 1/27

9:12 pm-11:59 pm

Nonstop2h 47m

Louisville Intl

Mon 2/2

12:00 pm-2:36 pm

Nonstop2h 36m

$239

MiamiLouisville

MIA - SDF

MIASDF

Miami

Fri 2/6

6:30 am-12:45 pm

1 stop6h 15m

Louisville Intl

Mon 2/9

6:25 am-5:10 pm

2 stops10h 45m

$254

MiamiLouisville

MIA - SDF

MIASDF

Miami

Wed 2/4

4:30 pm-10:45 pm

1 stop6h 15m

Louisville Intl

Thu 2/5

6:25 am-5:10 pm

2 stops10h 45m

$254

MiamiLouisville

MIA - SDF

MIASDF

Miami

Tue 1/27

6:55 am-11:10 am

1 stop4h 15m

Louisville Intl

Mon 2/2

12:50 pm-6:35 pm

1 stop5h 45m

$259

MiamiLouisville

MIA - SDF

MIASDF

Miami

Tue 1/20

7:15 am-1:35 pm

1 stop6h 20m

Louisville Intl

Tue 1/20

5:45 pm-10:00 pm

1 stop4h 15m

$261

MiamiLouisville

MIA - SDF

MIASDF

Miami

Sun 1/25

6:02 am-1:00 pm

2 stops30h 58m

Louisville Intl

Sun 2/1

3:36 pm-11:56 am

2 stops20h 20m

$274

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/30

Showing 1-10 of 23 results

Best time to book a flight from Florida Keys to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Florida Keys with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florida Keys to Louisville

No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Louisville

See what other customers who have flown with Southwest, Delta, and American Airlines from Florida Keys to Louisville have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,251 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Southwest

8.0

Very good

4,251 reviews

Southwest

8.0

Very good

4,251 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Delta

7.9

Good

8,016 reviews

Southwest

8.0

Very good

4,251 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

American Airlines

7.2

Good

11,074 reviews

Southwest

8.0

Very good

4,251 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Spirit Airlines

6.3

Okay

8,234 reviews

Southwest

8.0

Very good

4,251 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

What airport do you fly into for flights to Louisville from Florida Keys?
Louisville Intl (SDF), located 5.3 mi from the city center, is the airport you fly into when you book flights from Florida Keys to Louisville.
How long is the flight from Florida Keys to Louisville?
American Airlines, Delta, and United Airlines can get you from Florida Keys to Louisville in just under 2h 47m. Your travel time can differ by up to 4h 34m. The distance from Florida Keys to Louisville is about 912 mi. This flight may include one or multiple stops.
What are the cheapest airlines to fly from Florida Keys to Louisville one-way?
To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $43. Allegiant Air flights start at $48 while deals on Southwest start at $89 one-way.
Can I find deals for flights from Florida Keys to Louisville that include hotel bookings?
Yes. In addition to deals on Florida Keys to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Florida Keys to Louisville?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florida Keys to Louisville.
Can I find deals for business class flights from Florida Keys to Louisville?
Yes. Cheapflights offers flight deals from Florida Keys to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Shepherdsville

Jeffersonville

Elizabethtown

Corydon

Bardstown

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$86+ Cheap flights from Florida Keys to Louisville (SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/28. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Florida Keys to Louisville with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Florida Keys to Louisville

Cheapest flights from Florida Keys to LouisvilleExplore the most affordable flight options available from Florida Keys to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 30, 2025.

Explore the most affordable flight options available from Florida Keys to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 30, 2025.

Find flight deals from Florida Keys to Louisville

Keep the following information in mind while searching for Florida Keys to Louisville flight deals. Data was last updated December 30, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Cheapflights Fare Finder

Use the filters below to find and compare flights from Florida Keys to Louisville that are best for you.

Best time to book a flight from Florida Keys to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Florida Keys with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Florida Keys to Louisville

Reviews of airlines servicing Louisville

See what other customers who have flown with Southwest, Delta, and American Airlines from Florida Keys to Louisville have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Florida Keys to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Louisville from Florida Keys?

How long is the flight from Florida Keys to Louisville?

What are the cheapest airlines to fly from Florida Keys to Louisville one-way?

Can I find deals for flights from Florida Keys to Louisville that include hotel bookings?

How can I find direct flights from Florida Keys to Louisville?

Can I find deals for business class flights from Florida Keys to Louisville?

Traveling to a place near Louisville?

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Alternative routes for Florida Keys to Louisville

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Cheapest flights from Florida Keys to Louisville
Explore the most affordable flight options available from Florida Keys to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 30, 2025.