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$98+ Cheap flights from Florida Keys to Louisville (SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/25. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — SDF
Mar 15 — Mar 221
Sun 3/15
Sun 3/22
1 adult, Economy
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Cheap flight deals from Florida Keys to Louisville

Cheapest flights from Florida Keys to Louisville
Explore the most affordable flight options available from Florida Keys to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 13, 2026.

This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/85:15 am
MIA
-
SDF
1 stop27h 21m
Multiple Airlines
Sat 5/168:06 pm
SDF
-
MIA
1 stop14h 26m
Multiple Airlines
Deal found 2/11$193
This Southwest deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/115:45 pm
MIA
-
SDF
1 stop5h 45m
Southwest
Wed 3/184:30 pm
SDF
-
MIA
1 stop5h 15m
Southwest
Deal found 2/9$197
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/75:15 am
MIA
-
SDF
1 stop8h 12m
Multiple Airlines
Sat 5/168:06 pm
SDF
-
MIA
1 stop14h 26m
Multiple Airlines
Deal found 2/11$198
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/119:07 pm
MIA
-
SDF
Nonstop2h 52m
American Airlines
Wed 3/186:07 am
SDF
-
MIA
Nonstop2h 43m
American Airlines
Deal found 2/9$199
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:10 am
MIA
-
SDF
2 stops9h 45m
Southwest
Wed 3/2511:25 am
SDF
-
MIA
1 stop6h 35m
Southwest
Deal found 2/10$202
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/105:35 pm
MIA
-
SDF
1 stop4h 25m
Southwest
Wed 3/115:50 pm
SDF
-
MIA
1 stop4h 25m
Southwest
Deal found 2/10$205
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/145:15 am
MIA
-
SDF
1 stop8h 12m
Multiple Airlines
Sun 5/172:27 pm
SDF
-
MIA
1 stop20h 05m
Multiple Airlines
Deal found 2/10$206
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:04 am
MIA
-
SDF
1 stop5h 07m
Delta
Tue 5/126:00 am
SDF
-
MIA
1 stop4h 53m
Delta
Deal found 2/11$209
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/257:15 am
MIA
-
SDF
1 stop6h 20m
Southwest
Sun 3/11:40 pm
SDF
-
MIA
1 stop9h 55m
Southwest
Deal found 2/10$210
This Southwest deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/196:15 am
MIA
-
SDF
1 stop4h 20m
Southwest
Mon 3/236:35 am
SDF
-
MIA
1 stop6h 45m
Southwest
Deal found 2/11$217
This Southwest deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:20 am
MIA
-
SDF
1 stop5h 20m
Southwest
Thu 5/142:40 pm
SDF
-
MIA
1 stop8h 10m
Southwest
Deal found 2/11$227
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/193:56 pm
EYW
-
SDF
1 stop6h 17m
United Airlines
Sun 2/229:00 am
SDF
-
EYW
1 stop6h 00m
United Airlines
Deal found 2/11$469

Find flight deals from Florida Keys to Louisville

Keep the following information in mind while searching for Florida Keys to Louisville flight deals. Data was last updated February 13, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$193
(Kiwi.com)

One-way from

$98
(Southwest)
Provider with most accurate pricing for Key West-Louisville Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Key West-Louisville Intl flights.
Search Deals
From Florida Keys to Louisville Intl
Search Deals
One-way flight from Florida Keys to Louisville Intl
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florida Keys to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 13, 2026.
Use the filters below to find and compare flights from Florida Keys to Louisville that are best for you.

Fly from

Florida Keys

Fly to

Louisville

Route

Depart

Return

Price

MiamiLouisville

MIA - SDF

MIASDF

Miami

Wed 3/11

5:45 pm-11:30 pm

1 stop5h 45m

Louisville Intl

Wed 3/18

4:30 pm-9:45 pm

1 stop5h 15m

$197

MiamiLouisville

MIA - SDF

MIASDF

Miami

Wed 3/11

9:07 pm-11:59 pm

Nonstop2h 52m

Louisville Intl

Wed 3/18

6:07 am-8:50 am

Nonstop2h 43m

$199

MiamiLouisville

MIA - SDF

MIASDF

Miami

Tue 3/10

5:35 pm-10:00 pm

1 stop4h 25m

Louisville Intl

Wed 3/11

5:50 pm-10:15 pm

1 stop4h 25m

$205

MiamiLouisville

MIA - SDF

MIASDF

Miami

Wed 5/6

4:44 pm-9:31 pm

1 stop4h 47m

Louisville Intl

Tue 5/12

3:39 pm-9:16 pm

1 stop5h 37m

$209

MiamiLouisville

MIA - SDF

MIASDF

Miami

Wed 2/25

7:15 am-1:35 pm

1 stop6h 20m

Louisville Intl

Sun 3/1

1:40 pm-11:35 pm

1 stop9h 55m

$210

MiamiLouisville

MIA - SDF

MIASDF

Miami

Thu 5/14

5:15 am-1:27 pm

1 stop8h 12m

Louisville Intl

Sun 5/17

6:55 pm-10:32 am

2 stops15h 37m

$218

MiamiLouisville

MIA - SDF

MIASDF

Miami

Tue 5/5

4:44 pm-9:31 pm

1 stop4h 47m

Louisville Intl

Sat 5/16

5:52 pm-11:41 pm

1 stop5h 49m

$249

MiamiLouisville

MIA - SDF

MIASDF

Miami

Tue 4/7

4:44 pm-9:16 pm

1 stop4h 32m

Louisville Intl

Sat 4/11

5:58 pm-10:26 pm

1 stop4h 28m

$250

MiamiLouisville

MIA - SDF

MIASDF

Miami

Tue 4/7

9:14 pm-11:59 pm

Nonstop2h 45m

Louisville Intl

Sun 4/12

6:01 am-8:38 am

Nonstop2h 37m

$257

MiamiLouisville

MIA - SDF

MIASDF

Miami

Fri 2/20

7:05 am-1:25 pm

1 stop6h 20m

Louisville Intl

Sat 2/21

4:50 pm-10:15 pm

1 stop5h 25m

$257

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/11

Showing 1-10 of 22 results
1
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Best time to book a flight from Florida Keys to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Florida Keys with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florida Keys to Louisville
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Louisville

Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated February 13, 2026.
See what other customers who have flown with Southwest, Delta, and American Airlines from Florida Keys to Louisville have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,284 reviews

Boarding

8.1

Entertainment

7.5

Food

7.0

Comfort

8.0

Overall

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,284 reviews
Southwest
8.0
Very good
4,284 reviews

Boarding

8.1

Entertainment

7.5

Food

7.0

Comfort

8.0

Overall

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,200 reviews
Southwest
8.0
Very good
4,284 reviews

Boarding

8.1

Entertainment

7.5

Food

7.0

Comfort

8.0

Overall

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,288 reviews
Southwest
8.0
Very good
4,284 reviews

Boarding

8.1

Entertainment

7.5

Food

7.0

Comfort

8.0

Overall

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Spirit Airlines
6.3
Okay
8,451 reviews
Southwest
8.0
Very good
4,284 reviews

Boarding

8.1

Entertainment

7.5

Food

7.0

Comfort

8.0

Overall

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Florida Keys to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Louisville from Florida Keys?

    Louisville Intl (SDF), located 5.3 mi from the city center, is the airport you fly into when you book flights from Florida Keys to Louisville.

  • How long is the flight from Florida Keys to Louisville?

    Southwest, American Airlines, and Delta can get you from Florida Keys to Louisville in just under 2h 52m. Your travel time can differ by up to 2h 53m. The distance from Florida Keys to Louisville is about 912 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Florida Keys to Louisville one-way?

    To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $43. Allegiant Air flights start at $48 while deals on Southwest start at $89 one-way.

  • Can I find deals for flights from Florida Keys to Louisville that include hotel bookings?

    Yes. In addition to deals on Florida Keys to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florida Keys to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florida Keys to Louisville.

  • Can I find deals for business class flights from Florida Keys to Louisville?

    Yes. Cheapflights offers flight deals from Florida Keys to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Jeffersonville
Elizabethtown
Corydon
Bardstown

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