What are the cheapest airlines to fly from Florida Keys to Louisville one-way?

To fly one-way, consider booking your trip with Southwest, which is currently one of the cheapest options available, starting at $89. Spirit Airlines flights start at $102 while deals on Delta start at $170 one-way.

What is the cheapest month to book a flight from Florida Keys to Louisville?

Currently, January is the cheapest month in which you can book a flight from Florida Keys to Louisville (average of $299). Flying from Florida Keys to Louisville in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

In terms of precipitation, rainfall in Louisville ranges from 3.1 - 5.3 inches per month. May is typically the wettest month, when rainfall can reach 5.3 in. September is typically the driest time to visit Louisville when rainfall is around 3.1 in.

If weather is an important factor for your trip to Louisville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 35.6 F).

How far in advance should I book a flight from Florida Keys to Louisville?

Travelers have found it’s best to book a flight 53 days in advance to save up to 163% compared to booking the same week of travel. As your travel date approaches, the cost of this flight route may potentially increase. While opting to book 53 days out may not be an option for all, there are still additional ways to secure a deal in the near future. You might find a flight from Florida Keys to Louisville 1-2 weeks in advance for as low as $288, or $354 for flights within the next 24 hours.

What is the cheapest month to fly from Florida Keys to Louisville?

Our data shows that January tends to be the cheapest month to fly to Louisville from Florida Keys. Users have commonly found prices around $305 for the month, but tickets can be as low as $158. Due to multiple factors, prepare for potentially higher prices in December.

What airport do you fly into for flights to Louisville from Florida Keys?

Louisville Intl (SDF), located 5.3 mi from the city center, is the airport you fly into when you book flights from Florida Keys to Louisville.

Can I find deals for flights from Florida Keys to Louisville that include hotel bookings?

Yes. In addition to deals on Florida Keys to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Florida Keys to Louisville?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florida Keys to Louisville.

Can I find deals for business class flights from Florida Keys to Louisville?

Yes. Cheapflights offers flight deals from Florida Keys to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$89+ Flights from Florida Keys to Louisville

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Cheap flight deals from Florida Keys to Louisville

Round-trip from	$159 (American Airlines)
One-way from	$89 (Southwest)

From Florida Keys to Louisville Intl

Search Deals

One-way flight from Florida Keys to Louisville Intl

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Find flight deals from Florida Keys to Louisville

Cheapest flights from Florida Keys to Louisville
Explore the most affordable flight options available from Florida Keys to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 1, 2025.

Wed 9/109:20 pmMIA - SDF

Nonstop2h 36mAmerican Airlines

Mon 9/156:31 amSDF - MIA

Nonstop2h 37mAmerican Airlines

Deal found 6/30

$159

Fri 8/226:05 amMIA - SDF

1 stop6h 25mSouthwest

Mon 8/257:00 amSDF - MIA

1 stop4h 50mSouthwest

Deal found 6/30

$178

Wed 8/208:10 amMIA - SDF

1 stop6h 06mDelta

Sun 8/248:10 amSDF - MIA

1 stop7h 10mDelta

Deal found 6/30

$197

Wed 9/174:48 pmMIA - SDF

1 stop21h 03mSpirit Airlines

Sun 9/212:46 pmSDF - MIA

1 stop18h 22mSpirit Airlines

Deal found 7/1

$233

Fri 8/228:01 pmMIA - SDF

2 stops22h 52mMultiple Airlines

Mon 8/2510:24 amSDF - MIA

2 stops28h 07mMultiple Airlines

Deal found 6/30

$291

Sat 7/262:08 pmEYW - SDF

1 stop6h 51mUnited Airlines

Wed 7/306:30 amSDF - EYW

1 stop6h 42mUnited Airlines

Deal found 6/30

$299

Fri 7/257:00 amEYW - SDF

1 stop7h 16mDelta

Wed 7/3012:50 pmSDF - EYW

1 stop4h 42mDelta

Deal found 6/30

$311

Fri 7/257:51 pmEYW - SDF

1 stop4h 22mAmerican Airlines

Wed 7/307:00 amSDF - EYW

2 stops9h 18mAmerican Airlines

Deal found 6/30

$316

Fri 7/2510:02 amEYW - SDF

3 stops28h 44mMultiple Airlines

Wed 7/309:46 amSDF - EYW

2 stops25h 55mMultiple Airlines

Deal found 6/30

$428

Best flights from Florida Keys to Louisville
Discover carefully curated flight deals from Florida Keys to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 1, 2025.

Wed 9/109:20 pmMIA - SDF

Nonstop2h 36mAmerican Airlines

Mon 9/156:31 amSDF - MIA

Nonstop2h 37mAmerican Airlines

Deal found 6/29

$159

Fri 8/226:05 amMIA - SDF

1 stop6h 25mSouthwest

Mon 8/257:00 amSDF - MIA

1 stop4h 50mSouthwest

Deal found 6/30

$178

Thu 9/256:00 amMIA - SDF

1 stop4h 00mDelta

Sun 9/288:10 amSDF - MIA

1 stop5h 18mDelta

Deal found 6/30

$197

Wed 11/58:41 pmMIA - SDF

2 stops20h 33mSpirit Airlines

Sun 11/96:40 pmSDF - MIA

1 stop15h 05mSpirit Airlines

Deal found 6/28

$239

Fri 8/14:51 pmMIA - SDF

2 stops21h 55mMultiple Airlines

Fri 8/1512:24 pmSDF - MIA

2 stops20h 40mMultiple Airlines

Deal found 6/29

$298

Sat 7/262:08 pmEYW - SDF

1 stop6h 51mUnited Airlines

Wed 7/306:30 amSDF - EYW

1 stop6h 42mUnited Airlines

Deal found 6/30

$299

Fri 7/257:00 amEYW - SDF

1 stop7h 16mDelta

Wed 7/3012:50 pmSDF - EYW

1 stop4h 42mDelta

Deal found 6/30

$311

Fri 7/257:51 pmEYW - SDF

1 stop4h 22mAmerican Airlines

Wed 7/307:00 amSDF - EYW

2 stops9h 18mAmerican Airlines

Deal found 6/30

$316

Fri 7/2510:02 amEYW - SDF

3 stops28h 44mMultiple Airlines

Wed 7/309:46 amSDF - EYW

2 stops25h 55mMultiple Airlines

Deal found 6/30

$428

Last-minute flights from Florida Keys to Louisville
Discover last-minute flight deals from Florida Keys to Louisville. Data last updated July 1, 2025 and is based on user searches.

Sun 7/610:11 amMIA - SDF

3 stops26h 20mMultiple Airlines

Thu 7/103:59 pmSDF - MIA

3 stops18h 50mMultiple Airlines

Deal found 6/30

$694

Thu 7/107:00 amMIA - SDF

3 stops26h 04mSpirit Airlines

Mon 7/146:26 pmSDF - MIA

2 stops19h 17mSpirit Airlines

Deal found 7/1

$389

Thu 7/109:34 pmMIA - SDF

Nonstop2h 39mAmerican Airlines

Mon 7/146:32 amSDF - MIA

Nonstop2h 32mAmerican Airlines

Deal found 7/1

$393

Thu 7/105:10 pmMIA - SDF

1 stop7h 05mSouthwest

Mon 7/145:40 pmSDF - MIA

1 stop5h 10mSouthwest

Deal found 7/1

$412

Fri 7/116:55 amMIA - SDF

1 stop4h 50mDelta

Mon 7/148:14 pmSDF - MIA

1 stop4h 41mDelta

Deal found 6/30

$341

Thu 7/245:48 pmMIA - SDF

1 stop15h 16mSpirit Airlines

Mon 7/286:26 pmSDF - MIA

3 stops17h 57mSpirit Airlines

Deal found 7/1

$300

Fri 7/257:00 amEYW - SDF

1 stop7h 16mDelta

Wed 7/3012:50 pmSDF - EYW

1 stop4h 42mDelta

Deal found 6/30

$311

Fri 7/257:51 pmEYW - SDF

1 stop4h 22mAmerican Airlines

Wed 7/307:00 amSDF - EYW

2 stops9h 18mAmerican Airlines

Deal found 6/30

$316

Fri 7/2510:02 amEYW - SDF

3 stops28h 44mMultiple Airlines

Wed 7/309:46 amSDF - EYW

2 stops25h 55mMultiple Airlines

Deal found 6/30

$428

Sat 7/262:08 pmEYW - SDF

1 stop6h 51mUnited Airlines

Wed 7/306:30 amSDF - EYW

1 stop6h 42mUnited Airlines

Deal found 6/30

$299

Wed 8/206:00 amMIA - SDF

1 stop5h 45mDelta

Sun 8/248:10 amSDF - MIA

1 stop7h 10mDelta

Deal found 6/30

$197

Fri 8/229:52 pmMIA - SDF

Nonstop2h 33mAmerican Airlines

Mon 8/255:57 pmSDF - MIA

Nonstop2h 33mAmerican Airlines

Deal found 6/30

$160

One-way flights from Florida Keys to Louisville
Search for one-way flight options from Florida Keys to Louisville. Find affordable one-way fares based on user searches. Data last updated July 1, 2025.

Thu 8/76:05 amMIA - SDF

1 stop6h 25mSouthwest

Deal found 6/30

$89

Sat 8/96:51 pmMIA - SDF

1 stop14h 13mSpirit Airlines

Deal found 7/1

$102

Thu 8/711:10 amMIA - SDF

3 stops24h 16mMultiple Airlines

Deal found 6/28

$163

Fri 8/87:00 amEYW - SDF

1 stop4h 45mDelta

Deal found 7/1

$170

Thu 9/189:20 pmMIA - SDF

Nonstop2h 36mAmerican Airlines

Deal found 6/30

$195

Fri 8/810:02 amEYW - SDF

3 stops28h 48mMultiple Airlines

Deal found 7/1

$282

Fri 8/81:13 pmEYW - SDF

2 stops9h 39mAmerican Airlines

Deal found 7/1

$324

Cheapflights Fare Finder

Use the filters below to find and compare flights from Florida Keys to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MiamiLouisville

MIA - SDF

MIASDF

Miami

Wed 9/10

9:20 pm-11:56 pm

Nonstop2h 36m

Louisville Intl

Mon 9/15

6:31 am-9:08 am

Nonstop2h 37m

$159

MiamiLouisville

MIA - SDF

MIASDF

Miami

Fri 8/22

6:05 am-12:30 pm

1 stop6h 25m

Louisville Intl

Mon 8/25

7:00 am-11:50 am

1 stop4h 50m

$178

MiamiLouisville

MIA - SDF

MIASDF

Miami

Wed 8/20

8:10 am-2:16 pm

1 stop6h 06m

Louisville Intl

Sun 8/24

8:10 am-3:20 pm

1 stop7h 10m

$197

MiamiLouisville

MIA - SDF

MIASDF

Miami

Wed 9/17

4:48 pm-1:51 pm

1 stop21h 03m

Louisville Intl

Sun 9/21

2:46 pm-9:08 am

1 stop18h 22m

$233

MiamiLouisville

MIA - SDF

MIASDF

Miami

Fri 8/22

8:01 pm-6:53 pm

2 stops22h 52m

Louisville Intl

Mon 8/25

10:24 am-2:31 pm

2 stops28h 07m

$291

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Sat 7/26

2:08 pm-8:59 pm

1 stop6h 51m

Louisville Intl

Wed 7/30

6:30 am-1:12 pm

1 stop6h 42m

$299

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Fri 7/25

7:00 am-2:16 pm

1 stop7h 16m

Louisville Intl

Wed 7/30

12:50 pm-5:32 pm

1 stop4h 42m

$311

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Fri 7/25

7:51 pm-12:13 am

1 stop4h 22m

Louisville Intl

Wed 7/30

7:00 am-4:18 pm

2 stops9h 18m

$316

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Fri 7/25

10:02 am-2:46 pm

3 stops28h 44m

Louisville Intl

Wed 7/30

9:46 am-11:41 am

2 stops25h 55m

$428

MiamiLouisville

MIA - SDF

MIASDF

Miami

Wed 8/6

7:10 am-12:35 pm

1 stop5h 25m

$89

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Showing 1-10 of 18 results

Best time to book a flight from Florida Keys to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Florida Keys with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florida Keys to Louisville

What is the cheapest time of day to fly from EOA to SDF?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Florida Keys to Louisville as you normally would.

Reviews of airlines servicing Louisville

See what other customers who have flown with Southwest, Delta, and United Airlines from Florida Keys to Louisville have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,275 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Southwest

8.0

Very good

4,275 reviews

Southwest

8.0

Very good

4,275 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Delta

8.0

Very good

7,974 reviews

Southwest

8.0

Very good

4,275 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

United Airlines

7.4

Good

8,858 reviews

Southwest

8.0

Very good

4,275 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

American Airlines

7.2

Good

10,000 reviews

Southwest

8.0

Very good

4,275 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Spirit Airlines

6.3

Okay

8,100 reviews

Southwest

8.0

Very good

4,275 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

What airport do you fly into for flights to Louisville from Florida Keys?
Louisville Intl (SDF), located 5.3 mi from the city center, is the airport you fly into when you book flights from Florida Keys to Louisville.
What are the cheapest airlines to fly from Florida Keys to Louisville one-way?
To fly one-way, consider booking your trip with Southwest, which is currently one of the cheapest options available, starting at $89. Spirit Airlines flights start at $102 while deals on Delta start at $170 one-way.
Can I find deals for flights from Florida Keys to Louisville that include hotel bookings?
Yes. In addition to deals on Florida Keys to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Florida Keys to Louisville?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florida Keys to Louisville.
Can I find deals for business class flights from Florida Keys to Louisville?
Yes. Cheapflights offers flight deals from Florida Keys to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Florida Keys to Louisville?
Currently, January is the cheapest month in which you can book a flight from Florida Keys to Louisville (average of $299). Flying from Florida Keys to Louisville in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Shepherdsville

Jeffersonville

Elizabethtown

Corydon

Bardstown

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$89+ Cheap flights from Florida Keys to Louisville (SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/7. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Florida Keys to Louisville with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Florida Keys to Louisville

Keep the following information in mind while searching for Florida Keys to Louisville flight deals. Data was last updated July 1, 2025.

Round-trip from

One-way from

Find flight deals from Florida Keys to Louisville

Cheapest flights from Florida Keys to LouisvilleExplore the most affordable flight options available from Florida Keys to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 1, 2025.

Explore the most affordable flight options available from Florida Keys to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 1, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Florida Keys to Louisville that are best for you.

Best time to book a flight from Florida Keys to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Florida Keys with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Florida Keys to Louisville

What is the cheapest time of day to fly from EOA to SDF?

Find hourly flight availability from Florida Keys to Louisville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 1, 2025.

Reviews of airlines servicing Louisville

See what other customers who have flown with Southwest, Delta, and United Airlines from Florida Keys to Louisville have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Florida Keys to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Louisville from Florida Keys?

What are the cheapest airlines to fly from Florida Keys to Louisville one-way?

Can I find deals for flights from Florida Keys to Louisville that include hotel bookings?

How can I find direct flights from Florida Keys to Louisville?

Can I find deals for business class flights from Florida Keys to Louisville?

What is the cheapest month to book a flight from Florida Keys to Louisville?

Traveling to a place near Florida Keys?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Florida Keys to Louisville

See prices for flight routes from nearby airports that may be better suited for you.

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Travel Smart

Cheapest flights from Florida Keys to Louisville
Explore the most affordable flight options available from Florida Keys to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 1, 2025.