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$90+ Cheap flights from Florida Keys to Louisville (SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — SDF
Dec 12 — Dec 191
Fri 12/12
Fri 12/19
1 adult, Economy
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Find flight deals from Florida Keys to Louisville

Cheapest flights from Florida Keys to Louisville
Explore the most affordable flight options available from Florida Keys to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 12, 2025.

This Delta deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/105:00 pmMIA - SDF
1 stop4h 31mDelta
Mon 12/153:16 pmSDF - MIA
1 stop6h 58mDelta
Deal found 11/10$197
This Delta deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/28:10 amMIA - SDF
1 stop5h 39mDelta
Sat 12/66:11 pmSDF - MIA
1 stop6h 35mDelta
Deal found 11/10$199
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/109:16 pmMIA - SDF
Nonstop2h 38mAmerican Airlines
Mon 12/154:18 pmSDF - MIA
1 stop6h 00mAmerican Airlines
Deal found 11/10$207
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/109:16 pmMIA - SDF
Nonstop2h 38mAmerican Airlines
Sun 12/147:00 amSDF - MIA
1 stop6h 20mAmerican Airlines
Deal found 11/10$218
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/29:02 pmMIA - SDF
Nonstop2h 41mAmerican Airlines
Sat 12/65:58 pmSDF - MIA
1 stop6h 54mAmerican Airlines
Deal found 11/10$224
This Kiwi.com deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/266:19 pmMIA - SDF
1 stop19h 56mMultiple Airlines
Tue 12/26:48 pmSDF - MIA
2 stops43h 19mMultiple Airlines
Deal found 11/10$226
This Southwest deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/107:10 amMIA - SDF
1 stop6h 05mSouthwest
Sun 12/1412:55 pmSDF - MIA
1 stop10h 30mSouthwest
Deal found 11/10$229
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/119:16 pmMIA - SDF
Nonstop2h 38mAmerican Airlines
Thu 12/181:50 pmSDF - MIA
1 stop7h 10mAmerican Airlines
Deal found 11/11$241
This Kiwi.com deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/266:19 pmMIA - SDF
1 stop19h 56mMultiple Airlines
Mon 12/18:52 pmSDF - MIA
2 stops22h 55mMultiple Airlines
Deal found 11/10$247
This Mytrip deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:28 pmMIA - SDF
2 stops22h 32mSpirit Airlines
Fri 12/511:55 amSDF - MIA
2 stops23h 17mSpirit Airlines
Deal found 11/12$257
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/47:40 amEYW - SDF
1 stop6h 31mDelta
Wed 12/1012:58 pmSDF - EYW
1 stop7h 08mDelta
Deal found 11/11$311
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/52:47 pmEYW - SDF
1 stop8h 45mUnited Airlines
Sun 12/79:00 amSDF - EYW
1 stop6h 24mUnited Airlines
Deal found 11/10$329

Cheap flight deals from Florida Keys to Louisville

Keep the following information in mind while searching for Florida Keys to Louisville flight deals. Data was last updated November 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$179
(American Airlines)

One-way from

$90
(Southwest)
Provider with most accurate pricing for Key West-Louisville Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Key West-Louisville Intl flights.
Search Deals
From Florida Keys to Louisville Intl
Search Deals
One-way flight from Florida Keys to Louisville Intl
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Florida Keys to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 12, 2025.
Use the filters below to find and compare flights from Florida Keys to Louisville that are best for you.

Fly from

Florida Keys

Fly to

Louisville

Route

Depart

Return

Price

MiamiLouisville

MIA - SDF

MIASDF

Miami

Wed 12/10

5:00 pm-9:31 pm

1 stop4h 31m

Louisville Intl

Mon 12/15

3:16 pm-10:14 pm

1 stop6h 58m

$197

MiamiLouisville

MIA - SDF

MIASDF

Miami

Fri 12/12

7:00 am-12:13 pm

1 stop5h 13m

Louisville Intl

Mon 12/15

3:16 pm-10:14 pm

1 stop6h 58m

$197

MiamiLouisville

MIA - SDF

MIASDF

Miami

Tue 12/2

2:11 pm-7:12 pm

1 stop5h 01m

Louisville Intl

Sat 12/6

3:05 pm-9:50 pm

1 stop6h 45m

$199

MiamiLouisville

MIA - SDF

MIASDF

Miami

Thu 12/4

7:00 am-12:13 pm

1 stop5h 13m

Louisville Intl

Sat 12/6

6:11 pm-12:46 am

1 stop6h 35m

$199

MiamiLouisville

MIA - SDF

MIASDF

Miami

Thu 1/22

8:15 am-2:36 pm

1 stop6h 21m

Louisville Intl

Tue 2/3

7:00 am-2:18 pm

1 stop7h 18m

$199

MiamiLouisville

MIA - SDF

MIASDF

Miami

Thu 12/4

9:16 pm-11:54 pm

Nonstop2h 38m

Louisville Intl

Sat 12/6

5:58 pm-12:52 am

1 stop6h 54m

$224

MiamiLouisville

MIA - SDF

MIASDF

Miami

Wed 12/10

7:10 am-1:15 pm

1 stop6h 05m

Louisville Intl

Sun 12/14

12:55 pm-11:25 pm

1 stop10h 30m

$229

MiamiLouisville

MIA - SDF

MIASDF

Miami

Fri 1/9

7:15 am-1:35 pm

1 stop6h 20m

Louisville Intl

Sun 1/11

7:25 am-11:50 am

1 stop4h 25m

$244

MiamiLouisville

MIA - SDF

MIASDF

Miami

Sat 1/17

7:15 am-11:35 am

1 stop4h 20m

Louisville Intl

Thu 1/22

3:32 pm-10:48 pm

1 stop7h 16m

$257

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Thu 12/4

7:40 am-2:11 pm

1 stop6h 31m

Louisville Intl

Wed 12/10

12:58 pm-8:06 pm

1 stop7h 08m

$311

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/12

Showing 1-10 of 31 results
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Best time to book a flight from Florida Keys to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Florida Keys with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florida Keys to Louisville

What is the cheapest time of day to fly from EOA to SDF?

Find hourly flight availability from Florida Keys to Louisville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 12, 2025.

It’s optimal to fly from Florida Keys to Louisville in the afternoon. By choosing this option you can save up to 54% on the cost of your flight, compared to a flight in the evening.

Reviews of airlines servicing Louisville

Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated November 12, 2025.
See what other customers who have flown with Southwest, Delta, and American Airlines from Florida Keys to Louisville have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,235 reviews

Comfort

8.0

Food

7.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,235 reviews
Southwest
8.0
Very good
4,235 reviews

Comfort

8.0

Food

7.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
8,009 reviews
Southwest
8.0
Very good
4,235 reviews

Comfort

8.0

Food

7.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,050 reviews
Southwest
8.0
Very good
4,235 reviews

Comfort

8.0

Food

7.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Spirit Airlines
6.3
Okay
8,139 reviews
Southwest
8.0
Very good
4,235 reviews

Comfort

8.0

Food

7.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Florida Keys to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Louisville from Florida Keys?

    Louisville Intl (SDF), located 5.3 mi from the city center, is the airport you fly into when you book flights from Florida Keys to Louisville.

  • How long is the flight from Florida Keys to Louisville?

    Delta, United Airlines, and American Airlines can get you from Florida Keys to Louisville in just under 4h 31m. Your travel time can differ by up to 4h 14m. The distance from Florida Keys to Louisville is about 912 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Florida Keys to Louisville that include hotel bookings?

    Yes. In addition to deals on Florida Keys to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florida Keys to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florida Keys to Louisville.

  • Can I find deals for business class flights from Florida Keys to Louisville?

    Yes. Cheapflights offers flight deals from Florida Keys to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Jeffersonville
Elizabethtown
Corydon
Bardstown

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