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$204+ Cheap flights from Myrtle Beach to Lexington (MYR - LEX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/28. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — LEX
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Lexington

Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Lexington (LEX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2025.

Round-trip from

$259
(Delta)

One-way from

$204
(Delta)

Popular in

August

Cheapest in

June

Average price

$258
From Myrtle Beach Intl to Lexington Blue Grass
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One-way flight from Myrtle Beach Intl to Lexington Blue Grass
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Highest demand for flights based on searches. 14% potential increase in price ($55 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Myrtle Beach to Lexington

Cheapest flights from Myrtle Beach to Lexington
Explore the most affordable flight options available from Myrtle Beach to Lexington. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/254:00 pmMYR - LEX
1 stop3h 14mDelta
Tue 10/281:14 pmLEX - MYR
1 stop4h 49mDelta
Deal found 9/14$259
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/115:00 amMYR - LEX
1 stop5h 54mAmerican Airlines
Sat 12/136:10 pmLEX - MYR
1 stop3h 55mAmerican Airlines
Deal found 9/15$293
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/255:21 amMYR - LEX
2 stops8h 30mAmerican Airlines
Tue 10/286:50 amLEX - MYR
2 stops8h 07mAmerican Airlines
Deal found 9/14$329
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/305:36 pmMYR - LEX
1 stop3h 38mAmerican Airlines
Sat 10/47:15 pmLEX - MYR
1 stop3h 53mAmerican Airlines
Deal found 9/14$353
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/811:04 amMYR - LEX
2 stops8h 03mAmerican Airlines
Mon 11/1011:04 amLEX - MYR
2 stops7h 51mAmerican Airlines
Deal found 9/16$362
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/249:25 pmMYR - LEX
2 stops41h 37mMultiple Airlines
Sun 10/269:41 pmLEX - MYR
1 stop20h 03mMultiple Airlines
Deal found 9/15$389

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Lexington that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Lexington that are best for you.

Fly from

Myrtle Beach

Fly to

Lexington

Route

Depart

Return

Price

Myrtle BeachLexington

MYR - LEX

MYRLEX

Myrtle Beach Intl

Sat 10/25

4:00 pm-7:14 pm

1 stop3h 14m

Lexington Blue Grass

Tue 10/28

1:14 pm-6:03 pm

1 stop4h 49m

$259

Myrtle BeachLexington

MYR - LEX

MYRLEX

Myrtle Beach Intl

Thu 12/11

5:00 am-10:54 am

1 stop5h 54m

Lexington Blue Grass

Sat 12/13

6:10 pm-10:05 pm

1 stop3h 55m

$293

Myrtle BeachLexington

MYR - LEX

MYRLEX

Myrtle Beach Intl

Sat 11/8

2:45 pm-7:44 pm

1 stop4h 59m

Lexington Blue Grass

Mon 11/10

4:35 pm-10:36 pm

1 stop6h 01m

$293

Myrtle BeachLexington

MYR - LEX

MYRLEX

Myrtle Beach Intl

Fri 11/28

6:00 am-9:27 am

1 stop3h 27m

$204

Myrtle BeachLexington

MYR - LEX

MYRLEX

Myrtle Beach Intl

Sat 11/29

8:15 pm-11:59 pm

1 stop3h 44m

$289

Myrtle BeachLexington

MYR - LEX

MYRLEX

Myrtle Beach Intl

Sun 9/28

5:15 am-10:32 am

1 stop5h 17m

$304

Myrtle BeachLexington

MYR - LEX

MYRLEX

Myrtle Beach Intl

Sun 9/28

6:00 am-9:21 am

1 stop3h 21m

$304

Myrtle BeachLexington

MYR - LEX

MYRLEX

Myrtle Beach Intl

Fri 11/28

2:45 pm-11:21 pm

2 stops8h 36m

$467

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/17

Best time to book a flight from Myrtle Beach to Lexington

Have a flexible travel schedule? Discover the best time to fly to Lexington from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Lexington

What is the cheapest month to book a flight from Myrtle Beach to Lexington?

Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to Lexington (average of $303). Flying from Myrtle Beach to Lexington in April is currently the most expensive (average of $390). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to LEX?

Find hourly flight availability from Myrtle Beach to Lexington. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

It’s typically best to fly out from Myrtle Beach to Lexington in the morning. Doing so could potentially save you 79% on the flight price compared to flying in the afternoon, which is usually more expensive.

Reviews of airlines servicing Lexington

Get insights into the airlines that provide service to Lexington. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Lexington. Reviews last updated September 17, 2025.
Read through reviews of airlines operating flights from Myrtle Beach to Lexington, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,961 reviews

Boarding

8.2

Crew

8.5

Overall

8.0

Food

7.3

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,961 reviews
Delta
8.0
Very good
7,961 reviews

Boarding

8.2

Crew

8.5

Overall

8.0

Food

7.3

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,961 reviews

Boarding

8.2

Crew

8.5

Overall

8.0

Food

7.3

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Lexington. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Myrtle Beach to Lexington?

    For as low as $259, Delta can have you in Lexington from Myrtle Beach in 3h 14m. There are 437 mi between Myrtle Beach and Lexington. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Myrtle Beach to Lexington round-trip?

    According to our current data, Delta ($185), and American Airlines ($238) offers the cheapest pricing from Myrtle Beach to Lexington. Delta is currently priced 42% below the average price you’ll pay for this route.

  • Can I find deals for flights from Myrtle Beach to Lexington that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Lexington flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Lexington?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Lexington.

  • Can I find deals for business class flights from Myrtle Beach to Lexington?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Lexington by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Lexington?

    Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to Lexington (average of $303). Flying from Myrtle Beach to Lexington in April is currently the most expensive (average of $390). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Lexington?

Book flights to Lexington if you plan to visit one of these locations
Georgetown
Berea
Frankfort

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Top 2 airlines flying from Myrtle Beach to Lexington

Discover the top 2 airlines that operate flights from Myrtle Beach to Lexington. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$185Average$293FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$238Average$322FlexibilityNo cancel feeOn-time71%

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